Optis 2

OPTIS2 is a facility dedicated for treatment of ocular tumors. It operates clinically since 2010 and has treated already over 1000 patients. OPTIS2 was built based on many years of experience with the ancestor facility, OPTIS (operated 1984 - 2010). Unlike gantries, OPTIS2 has a fixed horizontal beam line. Instead of moving with a beam around patient, the optimal direction for the beam to enter into patient is achieved by moving and rotating with patient in front of the fixed beam.

More than 99 % of the original protons extracted from the cyclotron is lost during the process of energy degradation from 230 MeV to 70 MeV (energy providing sufficient range for any human eye). In order to achieve short treatment times (~1 minute), a double-scattering process was applied in OPTIS2 nozzle to ensure high efficiency of transport of 70 MeV proton beam. The range shifter set the range and ensures pre-scattering of proton pencil beam. In the next step, the beam passes through a scatter foil which broadens the beam and ensures homogeneous field at the isocentric plane. OPTIS2 uses in total 9 scatter foils, each dedicated to a specific interval of ranges. Spread-out Bragg peak (SOBP) is realized using dedicated modulator wheels. OPTIS2 can deliver a homogeneous circular field of maximal 35 mm diameter. However, this field is reduced for each patient, using individually milled cupper collimator aperture.

Achieved dose distribution is characterized by a steep distal and lateral fall-off. On average, the lateral and distal penumbras are 1.4 mm and 1.5 mm, respectively. OPTIS2 allows precise delivery of the requested range (2SD = 0.13 mm) and dose in the SOBP (2SD = 1.9%).

For an accurate patient positioning in respect to the treatment beam, OPTIS2 areal is equipped with two x-rays units aligned with the treatment isocenter providing orthogonal imaging of patient’s eye. Patient is seated in a treatment chair facing the nozzle with his head immobilized using individual mask and bite block. The chair is mounted on a hexapod robot allowing a 6-degrees-of-freedom positioning of patient. Position of an eye (gazing angle) is defined through the fixation light – a small LED that can be placed to any point in the proximity of the nozzle and patient has to watch. Intrafractional motion of patient eye is monitored using compact surveillance cameras.