The Laboratory of Multiscale Bioimaging (LMB) investigates the molecular structure and dynamics of complex molecular machines and cascades in the context of the living cell.
Lab News & Scientific Highlights
Neue Einsichten in eine seltene Krankheit
PSI-Forschende entschlüsseln, wie genetische Defekte menschliche Flimmerhärchen auf unterschiedliche Weise schädigen – ein Schritt zur besseren Diagnose einer bisher wenig verstandenen Erkrankung: der Primären Ciliären Dyskenie.
Demystifying electron ptychography with the PtychoScopy tool
The open-source PtychoScopy tool guides users towards higher quality and faster electron ptychographic reconstructions.
Gold nanoparticle dynamics on graphene probed by convergent beam electron diffraction.
Dynamics of single Au nanoparticles on graphene were probed simultaneously in real- and diffraction space by time-series convergent beam electron diffraction.
Publications
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Chen Y, Sun X, Tang Y, Tan Y, Guo C, Pan T, et al.
Pathogenic mutation ΔK280 promotes hydrophobic interactions involving microtubule-binding domain and enhances liquid-liquid phase separation of tau
Small. 2025; 21(6): 2406429 (12 pp.). https://doi.org/10.1002/smll.202406429
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Aidukas T, Phillips NW, Diaz A, Poghosyan E, Müller E, Levi AFJ, et al.
High-performance 4-nm-resolution X-ray tomography using burst ptychography
Nature. 2024; 632(8023): 81-88. https://doi.org/10.1038/s41586-024-07615-6
DORA PSI -
Asmara TC, Green RJ, Suter A, Wei Y, Zhang W, Knez D, et al.
Emergence of interfacial magnetism in strongly‐correlated nickelate‐titanate superlattices
Advanced Materials. 2024; 36(38): 2310668 (14 pp.). https://doi.org/10.1002/adma.202310668
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Braunger JM, Cammarata LV, Sornapudi TR, Uhler C, Shivashankar GV
Transcriptional changes are tightly coupled to chromatin reorganization during cellular aging
Aging cell. 2024; 23(3): e14056 (18 pp.). https://doi.org/10.1111/acel.14056
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Cellini A, Shankar MK, Nimmrich A, Hunt LA, Monrroy L, Mutisya J, et al.
Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography
Nature Chemistry. 2024; 16: 624-632. https://doi.org/10.1038/s41557-023-01413-9
DORA PSI