Laboratory of Multiscale Bioimaging (LMB)

The Laboratory of Multiscale Bioimaging (LMB) investigates the molecular structure and dynamics of complex molecular machines and cascades in the context of the living cell.

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Research and Technology Innovation

Lab News & Scientific Highlights

22.07.2024

•Health Innovation

•6 min

Brustkrebs-Charakterisierung mit KI

Medizin Diagnostik KI

Forschende des PSI und des MIT entwickeln einen neuen Ansatz aufgrund einer Kombination aus Bildgebung und künstlicher Intelligenz, um das Staging bei Brustkrebs zu verbessern.

Within the cell, some proteins can condense into droplets: a concept known as liquid-liquid phase separation. While this enables important cellular functions, there has been speculation that it can also be a precursor to pathological protein aggregation. (Image: Adobe Stock)

15.07.2024

•Health Innovation

•7 min

Protein droplets likely don’t cause Parkinson’s

Medical Science

Study deepens our understanding of neurodegenerative diseases linked to protein aggregation.

02.05.2024

EMBO workshop on Nuclear Mechano-Genomics

The EMBO-workshop on Nuclear Mechano-Genomics taking place from April 16 to April 19, 2024 in Sardinia, Italy, was a great success.

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Publications

Aidukas T, Phillips NW, Diaz A, Poghosyan E, Müller E, Levi AFJ, et al.
High-performance 4-nm-resolution X-ray tomography using burst ptychography
Nature. 2024; 632(8023): 81-88. https://doi.org/10.1038/s41586-024-07615-6
DORA PSI
Asmara TC, Green RJ, Suter A, Wei Y, Zhang W, Knez D, et al.
Emergence of interfacial magnetism in strongly‐correlated nickelate‐titanate superlattices
Advanced Materials. 2024; 36(38): 2310668 (14 pp.). https://doi.org/10.1002/adma.202310668
DORA PSI
Braunger JM, Cammarata LV, Sornapudi TR, Uhler C, Shivashankar GV
Transcriptional changes are tightly coupled to chromatin reorganization during cellular aging
Aging cell. 2024; 23(3): e14056 (18 pp.). https://doi.org/10.1111/acel.14056
DORA PSI
Cellini A, Shankar MK, Nimmrich A, Hunt LA, Monrroy L, Mutisya J, et al.
Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography
Nature Chemistry. 2024; 16: 624-632. https://doi.org/10.1038/s41557-023-01413-9
DORA PSI
Cen T, Zhang Z, Torrent L, Müller E, Ludwig C, Testino A
Airborne metal nanoparticles released by azides detonation: determination and potential public exposure
Scientific Reports. 2024; 14(1): 17312 (11 pp.). https://doi.org/10.1038/s41598-024-67540-6
DORA PSI