Frontpage of the Paul Scherrer Institut (PSI)

PSI Aerial View
The Paul Scherrer Institute, PSI, is the largest research institute for natural and engineering sciences within Switzerland. We perform world-class research in three main subject areas: Matter and Material; Energy and the Environment; and Human Health. By conducting fundamental and applied research, we work on long-term solutions for major challenges facing society, industry and science.
19 October 2020
Teaser Proteinkristalle

Wait and see, and grow crystals

Research Using Synchrotron Light Biology Human Health Medical Science

At PSI, researchers decipher the structure of the proteins in bacteria and viruses. This knowledge can aid, for example, in the development of drugs against infectious diseases. But before the investigation can begin, an extremely tricky problem has to be solved: the crystallisation of the molecules.

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14 October 2020
Doming

A protein's unexpected "doming"

Human Health Medical Science Radiopharmacy

Researchers have coaxed a secret out of the vital protein cytochrome c that it kept well-hidden up to now. Measurements at the X-ray free-electron laser SwissFEL reveal structural changes that science had previously ruled out for this kind of biomolecule.

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12 October 2020
Strahllinien-Wissenschaftler Vincent Olieric montiert eine Proteinkristallprobe, um sie an der SLS zu vermessen.

Messungen am PSI ermöglichten detailliertes Verständnis der Gen-Schere

Research Using Synchrotron Light Biology User experiments

PSI congratulates Emmanuelle Charpentier and Jennifer Doudna on winning this year's Nobel Prize in Chemistry. Experiments at the Swiss Light Source SLS in 2013 made it possible to elucidate the structure of the protein complex CRISPR-Cas9.

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