Laboratory for Macromolecules and BioimagingLSB
Highlights
Nanoworlds in 3-D
Tomographic images from the interior of fossils, brain cells, or computer chips are yielding new insights into the finest of structures. These 3-D images are made possible by the X-ray beams of the Swiss Light Source SLS, together with detectors and sophisticated computer algorithms developed at PSI.
Short film of a magnetic nano-vortex
Using a newly developed imaging method, researchers were able to visualise the magnetic structure inside a material with nanoscale resolution. They succeeded in creating a short "film" consisting of seven movie frames that shows, for the first time in 3D, how tiny vortices of the magnetisation deep within a material change over time.
Innovation Award on Synchrotron Radiation 2019 for the development of XFEL detectors using the adaptive gain principle
The Innovation Award on Synchrotron Radiation 2019 was given to the researchers Prof. Heinz Graafsma from Desy and Dr. Aldo Mozzanica and Dr. Bernd Schmitt both from the Paul Scherrer Institute. The three physicists were honored for their contributions to the development of detectors for XFEL applications based on the dynamic gain switching principle enabling simultaneously single photon resolution and a large dynamic range. The laudation was held by Prof. Edgar Weckert from Desy. The Synchrotron Radiation Innovation Award is sponsored by SPECS GmbH and BESTEC GmbH.
Animal embryos evolved before animals
Detailed characterization of cellular structure and development of exceptionally preserved ancient tiny fossils from South China by synchrotron based X-ray tomographic microscopy at TOMCAT led an international team of researchers from the University of Bristol and Nanjing Institute of Geology and Palaeontology to the discovery that animal-like embryos evolved long before the first animals appear in the fossil record.
A fast and precise look into fibre-reinforced composites
Researchers at the Paul Scherrer Institute PSI have developed a new process with which fibre-reinforced composite materials can be precisely X-rayed. This could help to develop better materials with novel properties.
3D imaging for planar samples with zooming
Researchers of the Paul Scherrer Institut have previously generated 3-D images of a commercially available computer chip. This was achieved using a high-resolution tomography method. Now they extended their imaging approach to a so-called laminography geometry to remove the requirement of preparing isolated samples, also enabling imaging at various magnification. For ptychographic X-ray laminography (PyXL) a new instrument was developed and built, and new data reconstruction algorithms were implemented to align the projections and reconstruct a 3D dataset. The new capabilities were demonstrated by imaging a 16 nm FinFET integrated circuit at 18.9 nm 3D resolution at the Swiss Light Source. The results are reported in the latest edition of the journal Nature Electronics. The imaging technique is not limited to integrated circuits, but can be used for high-resolution 3D imaging of flat extended samples. Thus the researchers start now to exploit other areas of science ranging from biology to magnetism.
Preventing tumour metastasis
Researchers at the Paul Scherrer Institute PSI, together with colleagues from the pharmaceutical company F. Hoffmann-La Roche AG, have taken an important step towards the development of an active substance against the metastasis of certain cancers. Using the Swiss Light Source SLS, they deciphered the structure of a receptor that plays a crucial role in the migration of cancer cells.
World record in time-resolved tomography
Researchers from the Helmholtz Zentrum Berlin (HZB) and the TOMCAT beamline have achieved a new world record in time-resolved tomography by measuring over 200 tomographies per second during heating of an evolving aluminium metal foam.
Observing solid-state batteries during deformation
PSI researchers have observed mechanical processes in solid-state batteries with unprecedented precision. Using X-ray tomography at the Swiss Light Source SLS, they discovered how fissures inside the batteries propagate. These insights can help to make batteries for electric cars or smartphones safer and more efficient.