Imaging strain in crystalline materials with high resolution can be a challenging task. Researchers demonstrate an original use of X-ray ptychography for this purpose: ptychographic topography.
Scientists decode the structure of the enzyme responsible for the ethane fixation by – beside others – using the SLS.
Crystal structure analysis, computer models, cell cultures – to pursue research on Sars-CoV-2, PSI is exploring many avenues. An overview.
Catalysts used in industry change their material structure over the years. Using a new method, PSI researchers have now studied this on the nanoscale.
Crystal structure of SARS-CoV-2 Orf9b in complex with human TOM70 suggests unusual virus-host interactions
In a study published in Nature Communications, researchers at the NHC Key Laboratory of Systems Biology of Pathogens in Beijing, China, in collaboration with the Paul Scherrer Institut characterize the interactions of SARS-CoV-2 orf9b and human TOM70 biochemically, and they determine the 2.2 Å crystal structure of the TOM70 cytosolic domain with a bound SARS-CoV-2 orf9b peptide.
Myelin 'insulates' our neurons enabling fast signal transduction in our brain. Myelin levels, integrity, and neuron orientations are important determinants of brain development and disease. Small-angle X-ray scattering tensor tomography (SAXS-TT) is a promising technique for non-destructive, stain-free imaging of brain samples, enabling quantitative studies of myelination and neuron orientations, i.e. of nano-scale properties imaged over centimeter-sized samples.
Researchers at Goethe University Frankfurt, in cooperation with the PSI have probably discovered another, previously unknown mechanism of action of the antiviral remdesivir.
In a study addressing the global health threat of drug resistance, researchers at the Biozentrum, University of Basel, have revealed how a new antibiotic, Darobactin, binds to the external membrane of gram-negative bacteria.
Detailed characterization of the tooth and jaw structure and development among shark ancestors by synchrotron based X-ray tomographic microscopy at TOMCAT led an international team of researchers from the Naturalis Biodiversity Center in Leiden and the University of Bristol to the discovery that while teeth evolved once, complex dentitions have been gained and lost many times in evolutionary history.