With its globally unique research infrastructure, PSI offers unrivalled opportunities for cutting-edge national and international research.
The main areas of research at PSI
Recent highlights from our research
Using AI to identify genetic perturbations from cell images
New AI identifies genetic perturbations in chromatin – a potential approach in diagnostics and drug development.
Pollutants often originate in the air
In the CLOUD experiment at CERN, PSI researchers have measured with unprecedented precision how harmful organic air pollutants are formed and dispersed.
A superlative milestone
PSI spin-off Araris Biotech AG achieves valuation at unicorn-level!
Interested in doing research at PSI? Do you want to use our infrastructure for cutting-edge research?
Find out more about our large-scale research facilities and other research centres.
Research Centers & Labs
Our research and service centres conduct internationally recognised cutting-edge research in the natural and engineering sciences and make highly complex large research facilities available to science and industry for their own research projects.
Scientific Highlights from our Centers
From coral berries to new therapies: uncovering the molecular glue mechanism of natural compounds
Researchers at the Center for Life Sciences and the Center for Scientific Computing, Theory, and Data at the Paul Scherrer Institute have identified the mechanism by which certain natural compounds interfere with cellular signaling. These ‘molecular glues’ have a therapeutic potential for the treatment of specific cancer types. Their latest study on this topic has been published in the journal Proceedings of the National Academy of Sciences of the United States of America.
Dr. Yingfang He has been honored with the Alavi-Mandell Award 2025
We congratulate Dr. Yingfang He for the excellent research work she did during her time at the Center for Radiopharmaceutical Sciences.
Nanostructure orientation in 3D with visible light by Tomographic Müller-Polarimetric Microscopy
We developed a new method, tomographic Müller-polarimetric microscopy (TMPM), that allows to retrieve at three-dimensional microscopic resolution the nanoscale structural information of the ultrastructure probed with polarized light in a non-destructive manner using a low cost and experimentally simple optical setup.