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Medicine

19 October 2020
Teaser Proteinkristalle

Wait and see, and grow crystals

Research Using Synchrotron Light Biology Human Health Medical Science

At PSI, researchers decipher the structure of the proteins in bacteria and viruses. This knowledge can aid, for example, in the development of drugs against infectious diseases. But before the investigation can begin, an extremely tricky problem has to be solved: the crystallisation of the molecules.

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14 October 2020
Doming

A protein's unexpected "doming"

Human Health Medical Science Radiopharmacy

Researchers have coaxed a secret out of the vital protein cytochrome c that it kept well-hidden up to now. Measurements at the X-ray free-electron laser SwissFEL reveal structural changes that science had previously ruled out for this kind of biomolecule.

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5 October 2020
teaser

More effective treatment of thyroid cancer

Human Health Medical Science Radiopharmacy

PSI researchers have found a more effective treatment for a form of thyroid cancer – and with fewer side effects – by increasing the uptake of the cancer drug in tumour cells. The results have been published in the medical journal Theranostics.

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30 September 2020
Teaser 5232 3/2020

Mites in the spotlight

Biology Human Health Medical Science

The world of microbes and viruses is extremely old and exceedingly diverse. With the large research facilities at PSI, researchers are peering deep inside this alien cosmos and investigating, above all, the proteins of these exotic beings.

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28 September 2020
Serena Psoroulas mit der Versuchsanordnung in der Gantry 1

New technique for ultrafast tumour therapy

Media Releases Human Health Medical Science Proton Therapy

For the first time, researchers at the Centre for Proton Therapy at PSI have tested ultrafast, high-dose irradiation with protons. The new, experimental FLASH technique could revolutionise radiation therapy for cancer.

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26 November 2019
Teaser Medikamente mit Strahlkraft

Brilliant medicines

Biology Human Health Radiopharmacy Medical Science

In the service of health, scientists at the Paul Scherrer Institute PSI work with radionuclides and develop agents to treat cancer and to detect tumours. Their research provides support to hospitals and is of great interest to Swiss industry.

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31 October 2019
Teaser zur Infografik Feuer frei auf Tumore

Open fire on tumours

Biology Human Health Proton Therapy Medical Science

At the treatment stations of the Centre for Proton Therapy at PSI, tumours can be precisely irradiated from any direction. An interactive graphic explains how the protons get from the source to the body in order to trigger the elimination of tumour tissue.

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3 October 2019
Damien Weber

"It's important to keep doing research"

Human Health Proton Therapy Medical Science

Proton therapy is time-consuming and more costly than conventional radiation therapy, but its accuracy in targeting tumours is unsurpassed. An interview with Damien Weber, head of the Centre for Proton Therapy at PSI.

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26 September 2019
Bestrahlung

Cancer cells under attack

Human Health Proton Therapy Medical Science

At PSI, cancer patients receive a therapy that is unique in Switzerland. Bombardment with protons wipes out cancer cells  –  and does so more precisely than with any other form of irradiation.

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22 August 2019
Teaser Chemokin-Rezeptor

Preventing tumour metastasis

Media Releases Biology Human Health Medical Science Research Using Synchrotron Light

Researchers at the Paul Scherrer Institute PSI, together with colleagues from the pharmaceutical company F. Hoffmann-La Roche AG, have taken an important step towards the development of an active substance against the metastasis of certain cancers. Using the Swiss Light Source SLS, they deciphered the structure of a receptor that plays a crucial role in the migration of cancer cells.

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24 June 2019
Teaser Choi Steinmetz

Molecular scissors stabilise the cell's cytoskeleton

Media Releases Biology Human Health Medical Science

Researchers at the Paul Scherrer Institute PSI have an important part of the regulatory cycle that is involved in the formation and degradation of the cytoskeleton. Among other things, they have watched molecular scissors at work.

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26 April 2019
teaser adenylate cyclase

Bringing information into the cell

Media Releases Biology Human Health Medical Science

Researchers at the Paul Scherrer Institute PSI have elucidated an important part of a siganalling pathway that transmits information through the cell membrane into the interior of a cell. This exists in all mammals and plays an important role, among other things, in the regulation of the heartbeat. The new findings could lead to new therapies.

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28 February 2019
Professor Beate Timmermann(Photo: West German Proton Therapy Centre Essen)

Children are her passion

Media Releases Medical Science Human Health Proton Therapy

At PSI, Beate Timmermann built up a programme providing proton therapy for children with cancer at the same time she was raising her own son. Today she is head of the Clinic for Particle Therapy at the West German Proton Therapy Centre in Essen (WPE) and is considered one of the most accomplished experts in this field.

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11 October 2018

Licence agreement with Swiss pharma firm for development of a cancer drug

Medical Science Human Health Radiopharmacy Industrial co-operation

A radioactive agent, developed at the Paul Scherrer Institute PSI to fight an especially malignant form of thyroid cancer, has the potential to become a blockbuster drug. Due to its structure, it might also be able to dock onto cells of other tumours and destroy them with its radiation. The Lausanne-based biopharmaceutical company Debiopharm wants to further develop the PSI agent to the point where it is approved as a drug. Debiopharm and PSI have now created the contractual basis for this.

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22 August 2018

A biotechnological revolution

Biology Medical Science Human Health Radiopharmacy

Gebhard Schertler is head of the research division Biology and Chemistry at the Paul Scherrer Institute PSI and professor for Structural Biology at ETH Zurich. In this interview he talks about biological research at PSI and the future of drug development.

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16 May 2018
teaser picture

Light for biomolecules and super-fast processes

Media Releases Biology Human Health SwissFEL Medical Science Matter and Material Materials Research Industrial co-operation Research Using Synchrotron Light

The 16th of May is the International Day of Light. The research carried out with light at PSI enables advances in biology and pharmacology and also promotes the development of new materials for data storage and new technologies for personalised medicine.

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14 May 2018
teaser picture

Opening: Advanced technology against cancer

Media Releases Medical Science Human Health Proton Therapy

With proton therapy, certain tumours can be irradiated with exceptional precision – while, the surrounding healthy tissue is optimally protected. In Switzerland, this kind of radiation therapy is only possible at PSI. In a joint project with the University Hospital Zurich and the University of Zurich, PSI has expanded its capacity with a state-of-the-art treatment facility: the new, 270-ton Gantry 3.

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3 August 2017
teaser picture

Testing the Limits for the Patients' Benefit

Human Health Medical Science Proton Therapy

Proton therapy is already a success story at the Paul Scherrer Institute PSI but researchers remain dedicated to making treatment faster and safer.

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7 June 2017

Big help for small children

Human Health Medical Science Proton Therapy

When small children develop cancer, the whole family is affected. Staff at the Paul Scherrer Institute PSI’s Centre for Proton Therapy combine target-oriented proton beam irradiation and a caring, warm-hearted atmosphere to help these children.

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27 April 2017

Getting a Handle on Safety

Medical Science Human Health Proton Therapy

Proton beams don’t just cure cancer. They can also damage healthy tissue. To make sure that this doesn’t happen, PSI’s Centre for Proton Therapy carries out over 350 safety tests a year. The results speak for themselves: several thousand patients have undergone proton irradiation treatment here in Villigen. There’s never been an accident.

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5232 01/2021

5232 — Das Magazin des Paul Scherrer Instituts

01/2021
in German
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