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Biology

12 April 2022
Tobias Mühlethaler

How to find anti-cancer agents

Media Releases Research Using Synchrotron Light Biology Health Innovation

PSI researchers have developed a new substance that disables a vital protein in the cell skeleton.

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21 March 2022
Emiliya Poghosyan

Cool newcomer

Biology

Cryo-electron microscopy can help resolve many open questions about light-sensitive proteins, rapidly and with high precision.

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7 March 2022
Proteine

The wondrous world of light antennas

Biology

How light receptors can be used to specifically switch processes in cells on and off.

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27 January 2022
Imad El Haddad

Asthma: diagnosis in a single breath

Biology Health Innovation Medical Science

PSI is involved in the development of a breath test that can be used to diagnose asthma. Imad El Haddad explains why such a test could be extremely useful – especially for children.

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10 January 2022
SLS 3D

Millions in funding for brain and quantum research

Research Using Synchrotron Light Materials Research Biology Health Innovation Future Technologies Quantum Research

The European Research Council approves PSI projects for the development of a quantum computer and brain research worth about 5 million euros.

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3 January 2022
Diane Barret

More insight into how vision works

Media Releases Biology Health Innovation

PSI scientists have shed light on the structure of an important component of the eye: CNG ion channels whose job is to relay optical signals to the brain.

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18 October 2021
(Photo:Shutterstock.com/1051483496)

New active agent against parasites

Media Releases Research Using Synchrotron Light Biology Health Innovation Medical Science

PSI researchers identify potential active agent against several unicellular parasites – including the pathogens that cause malaria and toxoplasmosis.

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28 September 2021
Roger Benoit

Protein distancing

Media Releases Biology Health Innovation

PSI researchers have developed a new method to attach proteins to the surface of virus-like particles.

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5 July 2021
Corona Dunkelziffer

Tracking down unreported Coronavirus cases

Research Using Synchrotron Light Biology Health Innovation Medical Science Research on Covid-19

The University Hospital of Zurich uses proteins made at PSI for Europe’s first large-scale serology study on coronavirus prevalence in Switzerland.

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16 June 2021
Teaser Xavier Deupi

How immune cells are activated

Biology Health Innovation Medical Science

A research consortium has deciphered the mechanism of CCR5 receptor activation, providing insights for the development of CCR5 drug antagonists for AIDS, cancer, and inflammatory diseases.

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6 May 2021
Teaser Tubulin

Cell cytoskeleton as target for new active agents

Media Releases Research Using Synchrotron Light Biology Health Innovation

Using a combination of computer simulations and laboratory experiments, PSI researchers have identified new binding sites for active agents on the vital protein tubulin.

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2 March 2021
teaser

Watching receptor proteins changing shape

Research Using Synchrotron Light SwissFEL Biology Health Innovation

In our bodies, G protein-coupled receptors mediate countless processes. PSI researcher Ramon Guixà talks about how he brings those receptor molecules to life on the computer screen.

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4 February 2021
teaser

"Ultimately, we aim to understand how diseases start in single cells"

Biology Health Innovation Medical Science Proton Therapy

Imaging and sequencing techniques combined with machine learning offer researchers countless opportunities to look inside cells with greater precision than ever before. G.V. Shivashankar, lab head at PSI, describes how such information can be used to find answers to pressing questions.

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26 November 2020
20-11-25_zlotnikov_copyright-ronald-seidel-igor-zlotnikov_teaser.jpg

Scientists determine the structure of glass-shaping protein in sponges

Research Using Synchrotron Light Biology Future Technologies

Measurements at the Swiss Light Source SLS have helped to understand how the only known natural protein-mineral crystal is formed. It is part of the fascinating glass skeleton of sponges.

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5 November 2020
Teaser ERC Grant

A new generation of optogenetic tools for research and medicine

Media Releases Biology

The European Research Council (ERC) is funding an interdisciplinary collaborative project with 10 million euros for the structural and biophysical analysis of selected photoreceptors and their development into "OptoGPCRs", light-controlled molecular switches with a wide range of applications in biology and medicine.

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19 October 2020
Teaser Proteinkristalle

Wait and see, and grow crystals

Research Using Synchrotron Light Biology Health Innovation Medical Science

At PSI, researchers decipher the structure of the proteins in bacteria and viruses. This knowledge can aid, for example, in the development of drugs against infectious diseases. But before the investigation can begin, an extremely tricky problem has to be solved: the crystallisation of the molecules.

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12 October 2020
Strahllinien-Wissenschaftler Vincent Olieric montiert eine Proteinkristallprobe, um sie an der SLS zu vermessen.

Measurements at PSI enabled detailed understanding of genetic scissors

Research Using Synchrotron Light Biology User experiments

PSI congratulates Emmanuelle Charpentier and Jennifer Doudna on winning this year's Nobel Prize in Chemistry. Experiments at the Swiss Light Source SLS in 2013 made it possible to elucidate the structure of the protein complex CRISPR-Cas9.

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30 September 2020
Teaser 5232 3/2020

Mites in the spotlight

Biology Health Innovation Medical Science

The world of microbes and viruses is extremely old and exceedingly diverse. With the large research facilities at PSI, researchers are peering deep inside this alien cosmos and investigating, above all, the proteins of these exotic beings.

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31 August 2020
May Sharpe

A question of binding

Research Using Synchrotron Light Large Research Facilities Biology Health Innovation Research on Covid-19

At PSI, researchers are screening molecule fragments to see if these bind to important proteins of the coronavirus SARS-CoV-2 and thus have the potential to disable it. They are hoping the many individual pieces of information will yield an answer as to what an effective drug might look like.

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6 August 2020
Prevot

Coronavirus advice: Ventilate, ventilate, ventilate!

Biology Health Innovation Research on Covid-19

SARS-CoV-2 might be transmitted via aerosols, that is, through the air. Researchers point this out in the journal Clinical Infectious Diseases. André Prévôt from PSI co-signed the publication. In this interview, he explains which precautionary measures he recommends.

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01/2023

5232 — The magazine of the Paul Scherrer Institute

01/2023
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