At PSI, researchers decipher the structure of the proteins in bacteria and viruses. This knowledge can aid, for example, in the development of drugs against infectious diseases. But before the investigation can begin, an extremely tricky problem has to be solved: the crystallisation of the molecules.
Researchers have coaxed a secret out of the vital protein cytochrome c that it kept well-hidden up to now. Measurements at the X-ray free-electron laser SwissFEL reveal structural changes that science had previously ruled out for this kind of biomolecule.
PSI congratulates Emmanuelle Charpentier and Jennifer Doudna on winning this year's Nobel Prize in Chemistry. Experiments at the Swiss Light Source SLS in 2013 made it possible to elucidate the structure of the protein complex CRISPR-Cas9.
PSI researchers have found a more effective treatment for a form of thyroid cancer – and with fewer side effects – by increasing the uptake of the cancer drug in tumour cells. The results have been published in the medical journal Theranostics.
An international team of scientists has identified a novel driver of new aerosol particle formation in the Arctic: iodic acid, a chemical compound, which had not previously been observed in the region.
An international expedition with the participation of the Paul Scherrer Institute PSI discovers advanced glacial melting at an elevation of more than 4,000 metres on the Grand Combin in Valais. In the Alps, it may almost be too late for the Ice Memory project, which aims to save ice cores as a climate archive for future generations of researchers.
The world of microbes and viruses is extremely old and exceedingly diverse. With the large research facilities at PSI, researchers are peering deep inside this alien cosmos and investigating, above all, the proteins of these exotic beings.
For the first time, researchers at the Centre for Proton Therapy at PSI have tested ultrafast, high-dose irradiation with protons. The new, experimental FLASH technique could revolutionise radiation therapy for cancer.
Future batteries need to store more energy, have longer life, and be safer and more environmentally friendly than today's batteries. The European initiative BATTERY 2030+, in which PSI is participating, is intended to help achieve these goals.
Researchers at the Paul Scherrer Institute PSI have for the first time identified special nano-vortices in a material: antiferromagnetic skyrmions.
PSI scientists have investigated a material that could be suitable for future data storage applications. They have manipulated the crystalline structure of their sample while measuring how this affects the material’s magnetic and electronic properties.
Zeolites are already indispensable additives in the chemical industry – researchers from PSI and ETH Zurich suggest ways to make them still more efficient.
Within the framework of an international project, researchers from the Paul Scherrer Institute PSI are helping to save a valuable environmental and climatic archive. During an expedition 4,000 metres above sea level on Grand Combin in the Alps, they are drilling ice cores from melting glaciers to preserve them in Antarctica.
Erstmals Live-Rundgang durch eine Grossforschungsanlage per Video-Stream. Am 9. September haben Interessierte exklusiv die Möglichkeit, sich von Experten des PSI durch den neuen Freie-Elektronen-Röntgenlaser SwissFEL führen zu lassen und zu erfahren, welche Rätsel der Materie und der Natur sich damit lösen lassen.
At PSI, researchers are screening molecule fragments to see if these bind to important proteins of the coronavirus SARS-CoV-2 and thus have the potential to disable it. They are hoping the many individual pieces of information will yield an answer as to what an effective drug might look like.
The Swiss Light Source SLS is set to get an upgrade to make excellent research possible in the coming decades as well. Hans Braun, SLS 2.0 project leader, talks about this undertaking in an interview.
SARS-CoV-2 might be transmitted via aerosols, that is, through the air. Researchers point this out in the journal Clinical Infectious Diseases. André Prévôt from PSI co-signed the publication. In this interview, he explains which precautionary measures he recommends.
Frankfurt scientists identify a possible weakness of the SARS-CoV-2 virus. They carried out part of their measurements at PSI's Swiss Light Source SLS. The research results are published this week in the scientific journal Nature.
With the high-intensity proton accelerator HIPA, the Paul Scherrer Institute generates elementary particles to clarify how the universe is structured. Using pions, muons, and neutrons, the researchers conduct experiments to test the standard model of particle physics.
PSI takes part in space research projects. This not only expands knowledge about our astronomical home, but also reinforces Switzerland's reputation as a reliable developer of sophisticated space equipment.