The Paul Scherrer Institute PSI is the largest research institute for natural and engineering sciences within Switzerland. We perform cutting-edge research in the fields of future technologies, energy and climate, health innovation and fundamentals of nature. By performing fundamental and applied research, we work on sustainable solutions for major challenges facing society, science and economy. PSI is committed to the training of future generations. Therefore, about one quarter of our staff are post-docs, post-graduates or apprentices. Altogether, PSI employs 2300 people. 

For the Center for Proton Therapy we are looking for a

PhD Student in AI-boost multimodality imaging for upright radiotherapy

Your tasks

We are offering a fully funded 3 years PhD position within the Marie Skłodowska-Curie Doctoral Network - UPLIFT, focusing on upright radiotherapy (RT)—a transformative approach to radiation treatment. This position (DC16) will develop a comprehensive multi-modality image-guided workflow for upright radiotherapy, establishing treatment planning, robustness, and margin guidelines based on the gathered upright imaging data and numerical phantom. 

Your main tasks will be: 

  • Develop a versatile image analysis framework (image segmentation, deformable registration, synthesis and reconstruction) for multi-modality multi-posture images used for upright radiotherapy; 
  • Generate anthropomorphic numerical (4D) phantoms for simulating upright anatomy and its possible variations. 
  • Design and validate an efficient multi-modal image guidance workflow for upright radio-/proton therapy. 
 You can find the overview of the UPLIFT consortium here Home - Uplift (uplift-project.eu)

Your profile

  • Master degree in Biomedical Engineering, Computer Science, Electrical Engineering, Physics, or related fields. 
  • Strong interest in radiotherapy, medical imaging, image analysis, and translational research. 
  • Proven experience in medical image analysis (image registration/segmentation, 4D motion modeling) and deep learning frameworks development is highly preferred. 
  • Excellent communication and written skills and ability to work in an interdisciplinary team.  
You will be matriculated at the ETH Zurich. 

You must not have resided or carried out their main activity (work, studies, etc.) in Switzerland for more than 12 months in the 36 months immediately before the recruitment date.

We offer

Our institution is based on an interdisciplinary, innovative and dynamic collaboration. You will profit from a systematic training on the job, in addition to personal development possibilities and our pronounced vocational training culture. If you wish to optimally combine work and family life or other personal interests, we are able to support you with our modern employment conditions and the on-site infrastructure.

For further information, please contact Dr Ye Zhang, phone +41 56 310 58 34. 

Please submit your application online by 16 June 2025 (including addresses of referees) for the position as a PhD (Index no.1723-03).

Paul Scherrer Institute, Human Resources Management, Serdal Varol, 5232 Villigen PSI, Switzerland