Dr. Emma Victoria Beale

Postdoctoral Researcher at SwissFEL
Forschungsstrasse 111
5232 Villigen PSI
Switzerland
Biography
Emma Beale is currently a postdoctoral researcher in the Alvra group at SwissFEL. She gained a First Class BSc (Hons) degree in Biochemistry at the University of Otago, New Zealand and then completed her DPhil in Structural Biology at the University of Oxford, U.K.. Her thesis 'Mechanisms of immunoglobulin deactivation by Streptococcus pyogenes' was carried out under the supervision of Prof. Nicole Zitzmann and Prof. Max Crispin.
Emma then continued into a post-doctoral research position at Diamond Light Source, U.K. on the new microfocus macromolecular crystallography beamline VMXm. She is now a post-doctoral researcher within the SwissFEL Alvra group with support from the PSI Career Return Program.
Peer reviewed publications
Crawshaw, A. D., Beale, E. V., Warren, A. J., Stallwood, A., Duller, G., Trincao, J., Evans, G. A Sample Preparation Pipeline for Microcrystals at the VMXm Beamline. Journal of Visualized Experiments (2021) doi: 10.3791/62306.
Beale, E. V., Waterman, D. G., Hecksel, C., van Rooyen, J., Gilchrist, J. B., Parkhurst, J. M., de Hass, F., Buijsse, B., Evans, G., Zhang, P. A Workflow for Protein Structure Determination from Thin Crystal Lamella by Micro-Electron Diffraction. Frontiers in Molecular Biosciences (2020) doi: 10.3389/fmolb.2020.00179.
Beale, E. V., Warren, A. J., Trincaõ, J., Beilsten-Edmands, J., Crawshaw, A. D., Sutton, G., Stuart, D. & Evans, G. Scanning electron microscopy as a method for sample visualization in protein X-ray crystallography. IUCrJ (2020) doi.org/10.1107/S2052252520003875.
Beale, H. J., Bolton, R., Marshall, S. A., Beale, E. V., Carr, S. B., Ebrahim, A., Moreno-Chicano, T., Hough, M. A., Worrall, J. A. R., Tews, I., Owen, R. I. Successful sample preparation for serial crystallography experiments. Journal of Applied Crystallography (2019) doi: 10.1107/S1600576719013517.
Duyvesteyn, H. M. E., Kotecha, A., Ginn, H. M., Hecksel, C. W., Beale, E. V., de Haas, F., Evans, G., Zhang, P., Chiu, W., Stuart, D. I. Machining protein microcrystals for structure determination by electron diffraction. PNAS (2018) doi: 10.1073/pnas.1809978115.
Warren, A., Evans, G., Trincao, J., Beale, E., Crawshaw, A., Duller, G., Stallwood, A., Lunnon, M., Butler, D. VMXm: a new micro/nanofocus protein crystallography beamline at Diamond. Acta Cryst. A (2018) doi: 10.1107/S2053273318095086.
Vasiljevic, S., Beale, E. V., Bonomelli, C., Easthope, I. S., Pritchard, L. K., Seabright, G. E., Caputo, A. T., Scanlan, C. N., Dalziel, M., Crispin, M. Redirecting adenoviruses to tumour cells using therapeutic antibodies: Generation of a versatile human bispecific adaptor. Molecular Immunology (2015) doi:10.1016/j.molimm.2015.08.014.
Dixon, E. V., Claridge, J. K., Harvey, D. J., Baruah, K., Yu, X., Vesiljevic, S., Mattick, S., Pritchard, L. K., Krishna, B., Scanlan, C. N., Schnell, J. R., Higgins, M. K., Zitzmann, N., Crispin, M. Fragments of Bacterial Endoglycosidase S and Immunoglobulin G Reveal Subdomains of each that Contribute to Deglycosylation. Journal of Biological Chemistry (2014) doi:10.1074/jbc.M113.532812.