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Human Health

Teaser Gantry 3
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In the field of Human Health, several research groups at the PSI are involved in research into fundamental questions in biology and the treatment of cancer. To this end, they are studying the structure of proteins – highly complex biomolecules that are responsible for countless processes in living organisms. Patients with specific types of cancer are treated with proton therapy at the institute. The radio pharmacy is developing drugs aimed at very small tumours that have spread throughout the body.

Read more at: Human Health
2 March 2021
teaser

Watching receptor proteins changing shape

Research Using Synchrotron Light SwissFEL Biology Human Health

In our bodies, G protein-coupled receptors mediate countless processes. PSI researcher Ramon Guixà talks about how he brings those receptor molecules to life on the computer screen.

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4 February 2021
teaser

"Ultimately, we aim to understand how diseases start in single cells"

Biology Human Health Medical Science Proton Therapy

Imaging and sequencing techniques combined with machine learning offer researchers countless opportunities to look inside cells with greater precision than ever before. G.V. Shivashankar, lab head at PSI, describes how such information can be used to find answers to pressing questions.

Read more
18 November 2020
Kaspar Dällenbach

Which particulate air pollution poses the greatest health risk?

Media Releases Energy and Environment Human Health Enviroment

The composition of particulate matter can influence its harmfulness to human health just as much as the amount, PSI researchers show in a newly published study. Experiments and computational modelling showed that in Europe high concentrations of particulate matter harmful to human health occur mainly in metropolitan areas.

Read more
19 October 2020
Teaser Proteinkristalle

Wait and see, and grow crystals

Research Using Synchrotron Light Biology Human Health Medical Science

At PSI, researchers decipher the structure of the proteins in bacteria and viruses. This knowledge can aid, for example, in the development of drugs against infectious diseases. But before the investigation can begin, an extremely tricky problem has to be solved: the crystallisation of the molecules.

Read more
14 October 2020
Doming

A protein's unexpected "doming"

Human Health Medical Science Radiopharmacy

Researchers have coaxed a secret out of the vital protein cytochrome c that it kept well-hidden up to now. Measurements at the X-ray free-electron laser SwissFEL reveal structural changes that science had previously ruled out for this kind of biomolecule.

Read more
5 October 2020
teaser

More effective treatment of thyroid cancer

Human Health Medical Science Radiopharmacy

PSI researchers have found a more effective treatment for a form of thyroid cancer – and with fewer side effects – by increasing the uptake of the cancer drug in tumour cells. The results have been published in the medical journal Theranostics.

Read more
30 September 2020
Teaser 5232 3/2020

Mites in the spotlight

Biology Human Health Medical Science

The world of microbes and viruses is extremely old and exceedingly diverse. With the large research facilities at PSI, researchers are peering deep inside this alien cosmos and investigating, above all, the proteins of these exotic beings.

Read more
28 September 2020
Serena Psoroulas mit der Versuchsanordnung in der Gantry 1

New technique for ultrafast tumour therapy

Media Releases Human Health Medical Science Proton Therapy

For the first time, researchers at the Centre for Proton Therapy at PSI have tested ultrafast, high-dose irradiation with protons. The new, experimental FLASH technique could revolutionise radiation therapy for cancer.

Read more
31 August 2020
May Sharpe

A question of binding

Research Using Synchrotron Light Large Research Facilities Biology Human Health

At PSI, researchers are screening molecule fragments to see if these bind to important proteins of the coronavirus SARS-CoV-2 and thus have the potential to disable it. They are hoping the many individual pieces of information will yield an answer as to what an effective drug might look like.

Read more
6 August 2020
Prevot

Coronavirus advice: Ventilate, ventilate, ventilate!

Biology Human Health

SARS-CoV-2 might be transmitted via aerosols, that is, through the air. Researchers point this out in the journal Clinical Infectious Diseases. André Prévôt from PSI co-signed the publication. In this interview, he explains which precautionary measures he recommends.

Read more
30 July 2020
Dr. May Elizabeth Sharpe

Covid-19 research: Anti-viral strategy with double effect

Research Using Synchrotron Light Biology Human Health

Frankfurt scientists identify a possible weakness of the SARS-CoV-2 virus. They carried out part of their measurements at PSI's Swiss Light Source SLS. The research results are published this week in the scientific journal Nature.

Read more
26 November 2019
Teaser Medikamente mit Strahlkraft

Brilliant medicines

Biology Human Health Radiopharmacy Medical Science

In the service of health, scientists at the Paul Scherrer Institute PSI work with radionuclides and develop agents to treat cancer and to detect tumours. Their research provides support to hospitals and is of great interest to Swiss industry.

Read more
22 November 2019
Christian Rüegg

Radionuclides for cancer therapy are in great demand

Human Health Research Using Neutrons

Radionuclides open up new options for treating cancer. Christian Rüegg, head of the Research with Neutrons and Muons Division at PSI, explains the significance of the Swiss Spallation Neutron Source SINQ at PSI.

Read more
21 November 2019
Teaser Krebsmedikament aus der Neutronenquelle

Cancer medicine using PSI’s neutron source

Human Health Research Using Neutrons

At the neutron source SINQ, PSI researchers are producing special radionuclides that aid in the development of new and more effectively targeted cancer therapies. In this they collaborate closely with the clinics in the surrounding area.

Read more
31 October 2019
Teaser zur Infografik Feuer frei auf Tumore

Open fire on tumours

Biology Human Health Proton Therapy Medical Science

At the treatment stations of the Centre for Proton Therapy at PSI, tumours can be precisely irradiated from any direction. An interactive graphic explains how the protons get from the source to the body in order to trigger the elimination of tumour tissue.

Read more
3 October 2019
Damien Weber

"It's important to keep doing research"

Human Health Proton Therapy Medical Science

Proton therapy is time-consuming and more costly than conventional radiation therapy, but its accuracy in targeting tumours is unsurpassed. An interview with Damien Weber, head of the Centre for Proton Therapy at PSI.

Read more
26 September 2019
Bestrahlung

Cancer cells under attack

Human Health Proton Therapy Medical Science

At PSI, cancer patients receive a therapy that is unique in Switzerland. Bombardment with protons wipes out cancer cells  –  and does so more precisely than with any other form of irradiation.

Read more
22 August 2019
Teaser Chemokin-Rezeptor

Preventing tumour metastasis

Media Releases Biology Human Health Medical Science Research Using Synchrotron Light

Researchers at the Paul Scherrer Institute PSI, together with colleagues from the pharmaceutical company F. Hoffmann-La Roche AG, have taken an important step towards the development of an active substance against the metastasis of certain cancers. Using the Swiss Light Source SLS, they deciphered the structure of a receptor that plays a crucial role in the migration of cancer cells.

Read more
24 June 2019
Teaser Choi Steinmetz

Molecular scissors stabilise the cell's cytoskeleton

Media Releases Biology Human Health Medical Science

Researchers at the Paul Scherrer Institute PSI have an important part of the regulatory cycle that is involved in the formation and degradation of the cytoskeleton. Among other things, they have watched molecular scissors at work.

Read more
26 April 2019
teaser adenylate cyclase

Bringing information into the cell

Media Releases Biology Human Health Medical Science

Researchers at the Paul Scherrer Institute PSI have elucidated an important part of a siganalling pathway that transmits information through the cell membrane into the interior of a cell. This exists in all mammals and plays an important role, among other things, in the regulation of the heartbeat. The new findings could lead to new therapies.

Read more
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5232 01/2021

5232 — Das Magazin des Paul Scherrer Instituts

01/2021
in German
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