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Production route of 44Sc

Promises of cyclotron-produced 44Sc as a diagnostic match for trivalent beta - emitters: In vitro and in vivo study of a 44Sc-DOTA-folate conjugate

Research Division Biology and Chemistry (BIO), Folate Receptor Targeting Group, Head Cristina Müller. In recent years, implementation of 68Ga-radiometalated peptides for PET imaging of cancer has attracted the attention of clinicians. Herein, we propose the use of 44Sc (half-life = 3.97 h, average β+ energy [Eβ+av] = 632 keV) as a valuable alternative to 68Ga (half-life = 68 min, Eβ+av = 830 keV) for imaging and dosimetry before 177Lu-based radionuclide therapy.

Material samples from the beam entrance window

MEGAPIE samples delivered to partners for post irradiation investigation

The MEGAWatt Pilot Experiment was operated for neutron generation with the PSI high intensity proton beam in 2006. The experiment utilized liquid target material, a lead bismuth eutectic. This marked a major milestone towards Accelerator Driven Systems (ADS), which are intended to be used for the incineration of nuclear waste.