Scientific Highlights

Datum
3 June 2021
SARS-CoV-2_orf9b

Crystal structure of SARS-CoV-2 Orf9b in complex with human TOM70 suggests unusual virus-host interactions

In a study published in Nature Communications, researchers at the NHC Key Laboratory of Systems Biology of Pathogens in Beijing, China, in collaboration with the Paul Scherrer Institut characterize the interactions of SARS-CoV-2 orf9b and human TOM70 biochemically, and they determine the 2.2 Å crystal structure of the TOM70 cytosolic domain with a bound SARS-CoV-2 orf9b peptide.

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11 May 2021
Teaser Remdesivir

How remdesivir works against the coronavirus

Health Innovation Medical Science Research on Covid-19

Researchers at Goethe University Frankfurt, in cooperation with the PSI have probably discovered another, previously unknown mechanism of action of the antiviral remdesivir.

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10 May 2021
darobactin

Combating antimicrobial resistance

In a study addressing the global health threat of drug resistance, researchers at the Biozentrum, University of Basel, have revealed how a new antibiotic, Darobactin, binds to the external membrane of gram-negative bacteria.

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30 July 2020
Dr. May Elizabeth Sharpe

Covid-19 research: Anti-viral strategy with double effect

Research Using Synchrotron Light Biology Health Innovation Research on Covid-19

Frankfurt scientists identify a possible weakness of the SARS-CoV-2 virus. They carried out part of their measurements at PSI's Swiss Light Source SLS. The research results are published this week in the scientific journal Nature.

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15 May 2020
Dikic lab

First MX results of the priority COVID-19 call

The Dikic group at the Goethe University in Frankfurt am Main, Germany has published the first results following the opening of the "PRIORITY COVID-19 Call” at SLS. 

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