Scientific Highlights and News

Dr. Manuel Guizar-Sicairos, currently Senior Scientist at PSI, was appointed as Associate Professor of Physics in EPF Lausanne and head of the Computational X-ray Imaging group in PSI.

Dr. Manuel Guizar-Sicairos was elected as a 2022 SPIE Fellow Member for his contributions to coherent lensless imaging, including ptychography and X-ray nano-tomography. The distinction was awarded in the SPIE’s Optics & Photonics conference in San Diego, California.

Hard X-ray cryo-tomography scanning of retina from healthy and inherited blindness specimen paves the way for correlative analysis after imaging at the cSAXS beamline.

Dr. Manuel Guizar-Sicairos, beamline scientist at the cSAXS beamline, is the 2019 recipient of the International Commission for Optics (ICO) Prize. The distinction was awarded in the EOSAM conference in Rome.

Myelin 'insulates' our neurons enabling fast signal transduction in our brain. Myelin levels, integrity, and neuron orientations are important determinants of brain development and disease. Small-angle X-ray scattering tensor tomography (SAXS-TT) is a promising technique for non-destructive, stain-free imaging of brain samples, enabling quantitative studies of myelination and neuron orientations, i.e. of nano-scale properties imaged over centimeter-sized samples.

The first experimental observation of three-dimensional magnetic ‘vortex rings’ provides fundamental insight into intricate nanoscale structures inside bulk magnets, and offers fresh perspectives for magnetic devices.

Dr. Manuel Guizar-Sicairos, beamline scientist at the cSAXS beamline, was elected as a Fellow Member of The Optical Society (OSA) for seminal contributions to methods and applications of coherent lensless imaging, ptychography, x-ray nanotomography, and new modalities of x-ray microscopy.

Researchers of the Paul Scherrer Institut have previously generated 3-D images of a commercially available computer chip. This was achieved using a high-resolution tomography method. Now they extended their imaging approach to a so-called laminography geometry to remove the requirement of preparing isolated samples, also enabling imaging at various magnification. For ptychographic X-ray laminography (PyXL) a new instrument was developed and built, and new data reconstruction algorithms were implemented to align the projections and reconstruct a 3D dataset. The new capabilities were demonstrated by imaging a 16 nm FinFET integrated circuit at 18.9 nm 3D resolution at the Swiss Light Source. The results are reported in the latest edition of the journal Nature Electronics. The imaging technique is not limited to integrated circuits, but can be used for high-resolution 3D imaging of flat extended samples. Thus the researchers start now to exploit other areas of science ranging from biology to magnetism.

Lithium ion batteries (LIB) are essential in modern everyday life, with increasing interest in enhancing their performance and lifetime. Secondary particles of Li-rich cathode material were examined with correlated ptychographic X-ray tomography and diffraction microscopy at different stages of cycling to probe the aging mechanism.