Scientific Highlights

Datum
3 June 2021
SARS-CoV-2_orf9b

Crystal structure of SARS-CoV-2 Orf9b in complex with human TOM70 suggests unusual virus-host interactions

In a study published in Nature Communications, researchers at the NHC Key Laboratory of Systems Biology of Pathogens in Beijing, China, in collaboration with the Paul Scherrer Institut characterize the interactions of SARS-CoV-2 orf9b and human TOM70 biochemically, and they determine the 2.2 Å crystal structure of the TOM70 cytosolic domain with a bound SARS-CoV-2 orf9b peptide.

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11 May 2021
Teaser Remdesivir

How remdesivir works against the coronavirus

Human Health Medical Science Research on Covid-19

Researchers at Goethe University Frankfurt, in cooperation with the PSI have probably discovered another, previously unknown mechanism of action of the antiviral remdesivir.

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10 May 2021
darobactin

Combating antimicrobial resistance

In a study addressing the global health threat of drug resistance, researchers at the Biozentrum, University of Basel, have revealed how a new antibiotic, Darobactin, binds to the external membrane of gram-negative bacteria.

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15 May 2020
Dikic lab

First MX results of the priority COVID-19 call

The Dikic group at the Goethe University in Frankfurt am Main, Germany has published the first results following the opening of the "PRIORITY COVID-19 Call” at SLS. 

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1 April 2019
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HERCULES school 2019 at SLS

In the week of April 1-5 PSI welcomes 20 PhD students and postdocs taking part in the European HERCULES 2019 school on Neutron and Synchrotron Radiation. They will attend lectures and perform two days of practical courses at several beam lines of the Swiss Light Source.

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12 November 2018
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A crystal-clear picture

Fast and accurate data collection for macromolecular crystallography using the JUNGFRAU detector.

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12 August 2018

First serial femtosecond crystallography (SFX) pilot user experiment at SwissFEL

On the 7th to 12th of August 2018, a collaborative group of scientists from the Paul Scherrer Institute and members of the LeadXpro and Heptares pharmaceutical companies led by Karol Nass (PSI macromolecular crystallography MX-SLS group) performed the first serial femtosecond crystallography (SFX) pilot user experiment at the SwissFEL X-ray free electron laser (XFEL).

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5 June 2018
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Rhine-Knee Regiomeeting 2018

Since it was first established in 1987, the annual Regio-Meeting has been instrumental in facilitating interactions in the structural biology community in southwestern Germany, the eastern region of France and an expanding area of Switzerland. It is set as an informal event to foster young scientists to discuss their research results in an international context. The 2018 edition will take place in the heart of Switzerland in Emmetten from September 26 to 28, 2018. Registration and abstract submission deadline: September 7, 2018.

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9 August 2017
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In Situ Serial Crystallography 2 Workshop at the SLS

A workshop dedicated to the presentation of the in meso in situ serial crystallography (IMISX) method (Huang et al. 2015, 2016 ActaD) for the X-ray structure determination of membrane proteins is organised at the Swiss Light Source at PSI for the second time. It will be held between November 27 and 29, 2017.

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