Publications

PDB structures measured at X06DA

Recent publications are listed below. For an extensive overview we kindly refer you to our publication repository DORA

  • Margreiter MA, Witzenberger M, Wasser Y, Davydova E, Janowski R, Metz J, et al.
    Small-molecule modulators of TRMT2A decrease PolyQ aggregation and PolyQ-induced cell death
    Computational and Structural Biotechnology Journal. 2022; 20: 443-458. https://doi.org/10.1016/j.csbj.2021.12.029
    DORA PSI
  • Abraham ET, Oecal S, Mörgelin M, Schmid PWN, Buchner J, Baumann U, et al.
    Collagen's primary structure determines collagen:HSP47 complex stoichiometry
    Journal of Biological Chemistry. 2021; 297(6): 101169 (13 pp.). https://doi.org/10.1016/j.jbc.2021.101169
    DORA PSI
  • Abrami L, Audagnotto M, Ho S, Marcaida MJ, Mesquita FS, Anwar MU, et al.
    Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains
    Nature Chemical Biology. 2021; 17(4): 438-447. https://doi.org/10.1038/s41589-021-00753-2
    DORA PSI
  • Adhireksan Z, Sharma D, Lee PL, Bao Q, Padavattan S, Shum WK, et al.
    Engineering nucleosomes for generating diverse chromatin assemblies
    Nucleic Acids Research. 2021; 49(9): E52 (12 pp.). https://doi.org/10.1093/nar/gkab070
    DORA PSI
  • Aeschimann W, Kammer S, Staats S, Schneider P, Schneider G, Rimbach G, et al.
    Engineering of a functional γ-tocopherol transfer protein
    Redox Biology. 2021; 38: 101773 (11 pp.). https://doi.org/10.1016/j.redox.2020.101773
    DORA PSI
  • Alali A, Zhang L, Li J, Zuo C, Wassouf D, Yan X, et al.
    Biosynthesis of the tricyclic aromatic type II polyketide rishirilide: new potential third ring oxygenation after three cyclization steps
    Molecular Biotechnology. 2021; 23: 502-514. https://doi.org/10.1007/s12033-021-00314-x
    DORA PSI
  • Alvigini L, Gran-Scheuch A, Guo Y, Trajkovic M, Saifuddin M, Fraaije MW, et al.
    Discovery, biocatalytic exploration and structural analysis of a 4-ethylphenol oxidase from Gulosibacter chungangensis
    ChemBioChem. 2021; 22(22): 3225-3233. https://doi.org/10.1002/cbic.202100457
    DORA PSI
  • Axer A, Jumde RP, Adam S, Faust A, Schäfers M, Fobker M, et al.
    Enhancing glycan stability via site-selective fluorination: modulating substrate orientation by molecular design
    Chemical Science. 2021; 12(4): 1286-1294. https://doi.org/10.1039/D0SC04297H
    DORA PSI
  • Bailleul G, Nicoll CR, Mascotti ML, Mattevi A, Fraaije MW
    Ancestral reconstruction of mammalian FMO1 enables structural determination, revealing unique features that explain its catalytic properties
    Journal of Biological Chemistry. 2021; 296: 100221 (13 pp.). https://doi.org/10.1074/jbc.RA120.016297
    DORA PSI
  • Banaś AM, Bocian-Ostrzycka KM, Dunin-Horkawicz S, Ludwiczak J, Wilk P, Orlikowska M, et al.
    Interplay between DsbA1, DsbA2 and C8J_1298 periplasmic oxidoreductases of Campylobacter jejuni and their impact on bacterial physiology and pathogenesis
    International Journal of Molecular Sciences. 2021; 22(24): 13451 (37 pp.). https://doi.org/10.3390/ijms222413451
    DORA PSI
  • Basler S, Studer S, Zou Y, Mori T, Ota Y, Camus A, et al.
    Efficient Lewis acid catalysis of an abiological reaction in a de novo protein scaffold
    Nature Chemistry. 2021; 13(3): 231-235. https://doi.org/10.1038/s41557-020-00628-4
    DORA PSI
  • Bauer V, Schmidtgall B, Gógl G, Dolenc J, Osz J, Nominé Y, et al.
    Conformational editing of intrinsically disordered protein by α-methylation
    Chemical Science. 2021; 12(3): 1080-1089. https://doi.org/10.1039/D0SC04482B
    DORA PSI
  • Brullo C, Rapetti F, Abbate S, Prosdocimi T, Torretta A, Semrau M, et al.
    Design, synthesis, biological evaluation and structural characterization of novel GEBR library PDE4D inhibitors
    European Journal of Medicinal Chemistry. 2021; 223: 113638 (13 pp.). https://doi.org/10.1016/j.ejmech.2021.113638
    DORA PSI
  • Chaoprasid P, Lukat P, Mühlen S, Heidler T, Gazdag E-M, Dong S, et al.
    Crystal structure of bacterial cytotoxic necrotizing factor CNFY reveals molecular building blocks for intoxication
    EMBO Journal. 2021; 40(4): e105202 (21 pp.). https://doi.org/10.15252/embj.2020105202
    DORA PSI
  • Collu G, Bierig T, Krebs A-S, Engilberge S, Varma N, Guixà-González R, et al.
    Chimeric single α-helical domains as rigid fusion protein connections for protein nanotechnology and structural biology
    Structure. 2021. https://doi.org/10.1016/j.str.2021.09.002
    DORA PSI
  • Conrady MC, Suarez I, Gogl G, Frecot DI, Bonhoure A, Kostmann C, et al.
    Structure of high-risk papillomavirus 31 E6 oncogenic protein and characterization of E6/E6AP/p53 complex formation
    Journal of Virology. 2021; 95(2): e00730-20 (15 pp.). https://doi.org/10.1128/JVI.00730-20
    DORA PSI
  • De Zitter E, Hugelier S, Duwé S, Vandenberg W, Tebo AG, Van Meervelt L, et al.
    Structure–function dataset reveals environment effects within a fluorescent protein model system
    Angewandte Chemie International Edition. 2021; 60(18): 10073-10081. https://doi.org/10.1002/anie.202015201
    DORA PSI
  • Diwo M, Michel W, Aurass P, Kuhle-Keindorf K, Pippel J, Krausze J, et al.
    NAD(H)-mediated tetramerization controls the activity of Legionella pneumophila phospholipase PlaB
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2021; 118(23): e2017046118 (10 pp.). https://doi.org/10.1073/pnas.2017046118
    DORA PSI
  • Dolbois A, Bedi RK, Bochenkova E, Müller A, Moroz-Omori EV, Huang D, et al.
    1,4,9-triazaspiro[5.5]undecan-2-one derivatives as potent and selective METTL3 inhibitors
    Journal of Medicinal Chemistry. 2021; 64(17): 12738-12760. https://doi.org/10.1021/acs.jmedchem.1c00773
    DORA PSI
  • Donohoue PD, Pacesa M, Lau E, Vidal B, Irby MJ, Nyer DB, et al.
    Conformational control of Cas9 by CRISPR hybrid RNA-DNA guides mitigates off-target activity in T cells
    Molecular Cell. 2021; 81(17): 3637-3649.e5. https://doi.org/10.1016/j.molcel.2021.07.035
    DORA PSI
  • Friedrich N, Stiegeler E, Glögl M, Lemmin T, Hansen S, Kadelka C, et al.
    Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization
    Nature Communications. 2021; 12(1): 6705 (18 pp.). https://doi.org/10.1038/s41467-021-27075-0
    DORA PSI
  • Hahn CJ, Lemaire ON, Kahnt J, Engilberge S, Wegener G, Wagner T
    Crystal structure of a key enzyme for anaerobic ethane activation
    Science. 2021; 373(6550): 118-121. https://doi.org/10.1126/science.abg1765
    DORA PSI
  • Hartmann M, Bibli S-I, Tews D, Ni X, Kircher T, Kramer JS, et al.
    Combined cardioprotective and adipocyte browning effects promoted by the eutomer of dual sEH/PPARγ modulator
    Journal of Medicinal Chemistry. 2021; 64(5): 2815-2828. https://doi.org/10.1021/acs.jmedchem.0c02063
    DORA PSI
  • Hassan M, Baussière F, Guzelj S, Sundin AP, Håkansson M, Kovačič R, et al.
    Structure-guided design of d-galactal derivatives with high affinity and selectivity for the galectin-8 N-terminal domain
    ACS Medicinal Chemistry Letters. 2021; 12(11): 1745-1752. https://doi.org/10.1021/acsmedchemlett.1c00371
    DORA PSI
  • Hatzopoulos GN, Kükenshöner T, Banterle N, Favez T, Flückiger I, Hamel V, et al.
    Tuning SAS-6 architecture with monobodies impairs distinct steps of centriole assembly
    Nature Communications. 2021; 12(1): 3805 (14 pp.). https://doi.org/10.1038/s41467-021-23897-0
    DORA PSI
  • Hermann J, Bischoff D, Grob P, Janowski R, Hekmat D, Niessing D, et al.
    Controlling protein crystallization by free energy guided design of interactions at crystal contacts
    Crystals. 2021; 11(6): 588 (18 pp.). https://doi.org/10.3390/cryst11060588
    DORA PSI
  • Iacovino LG, Pinzi L, Facchetti G, Bortolini B, Christodoulou MS, Binda C, et al.
    Promising non-cytotoxic monosubstituted chalcones to target monoamine oxidase-B
    ACS Medicinal Chemistry Letters. 2021; 12(7): 1151-1158. https://doi.org/10.1021/acsmedchemlett.1c00238
    DORA PSI
  • Johansson E, Wu X, Yu B, Yang Z, Cao Z, Wiberg C, et al.
    Insulin binding to the analytical antibody sandwich pair OXI‐005 and HUI‐018: epitope mapping and binding properties
    Protein Science. 2021; 30(2): 485-496. https://doi.org/10.1002/pro.4009
    DORA PSI
  • Kannt A, Rajagopal S, Hallur MS, Swamy I, Kristam R, Dhakshinamoorthy S, et al.
    Novel inhibitors of nicotinamide-N-methyltransferase for the treatment of metabolic disorders
    Molecules. 2021; 26(4): 991 (22 pp.). https://doi.org/10.3390/molecules26040991
    DORA PSI
  • Kitagawa H, Kikuchi M, Sato S, Watanabe H, Umezawa N, Kato M, et al.
    Structure-based identification of potent lysine-specific demethylase 1 inhibitor peptides and temporary cyclization to enhance proteolytic stability and cell growth-inhibitory activity
    Journal of Medicinal Chemistry. 2021; 64(7): 3707-3719. https://doi.org/10.1021/acs.jmedchem.0c01371
    DORA PSI
  • Kroupova A, Ackle F, Asanović I, Weitzer S, Boneberg FM, Faini M, et al.
    Molecular architecture of the human tRNA ligase complex
    eLife. 2021; 10: e71656 (28 pp.). https://doi.org/10.7554/eLife.71656
    DORA PSI
  • Kröger P, Shanmugaratnam S, Ferruz N, Schweimer K, Höcker B
    A comprehensive binding study illustrates ligand recognition in the periplasmic binding protein PotF
    Structure. 2021; 29(5): 433-443. https://doi.org/10.1016/j.str.2020.12.005
    DORA PSI
  • Krüger B, Galuskin EV, Galuskina IO, Krüger H, Vapnik Y
    Kahlenbergite KAl11O17, a new β-alumina mineral and Fe-rich hibonite from the Hatrurim Basin, the Negev desert, Israel
    European Journal of Mineralogy. 2021; 33(4): 341-355. https://doi.org/10.5194/ejm-33-341-2021
    DORA PSI
  • Lemaire ON, Wagner T
    Gas channel rerouting in a primordial enzyme: structural insights of the carbon-monoxide dehydrogenase/acetyl-CoA synthase complex from the acetogen Clostridium autoethanogenum
    Biochimica et Biophysica Acta: Bioenergetics. 2021; 1862(1): 148330 (14 pp.). https://doi.org/10.1016/j.bbabio.2020.148330
    DORA PSI
  • Li Y, Bedi RK, Wiedmer L, Sun X, Huang D, Caflisch A
    Atomistic and thermodynamic analysis of N6-methyladenosine (m6A) recognition by the reader domain of YTHDC1
    Journal of Chemical Theory and Computation. 2021; 17(2): 1240-1249. https://doi.org/10.1021/acs.jctc.0c01136
    DORA PSI
  • Marzullo P, Boiarska Z, Pérez-Peña H, Abel AC, Álvarez-Bernad B, Lucena-Agell D, et al.
    Maytansinol derivatives: side reactions as a chance for new tubulin binders
    Chemistry: A European Journal. 2021. https://doi.org/10.1002/chem.202103520
    DORA PSI
  • Miró-Vinyals C, Stein A, Fischer S, Ward TR, Deliz Liang A
    HaloTag engineering for enhanced fluorogenicity and kinetics with a styrylpyridium dye
    ChemBioChem. 2021. https://doi.org/10.1002/cbic.202100424
    DORA PSI
  • Mishra K, Fuenzalida-Werner JP, Pennacchietti F, Janowski R, Chmyrov A, Huang Y, et al.
    Genetically encoded photo-switchable molecular sensors for optoacoustic and super-resolution imaging
    Nature Biotechnology. 2021. https://doi.org/10.1038/s41587-021-01100-5
    DORA PSI
  • Monsarrat C, Compain G, André C, Engilberge S, Martiel I, Oliéric V, et al.
    Iterative structure-based optimization of short peptides targeting the bacterial sliding clamp
    Journal of Medicinal Chemistry. 2021; 64(23): 17063-17078. https://doi.org/10.1021/acs.jmedchem.1c00918
    DORA PSI
  • Moroz‐Omori EV, Huang D, Kumar Bedi R, Cheriyamkunnel SJ, Bochenkova E, Dolbois A, et al.
    METTL3 inhibitors for epitranscriptomic modulation of cellular processes
    ChemMedChem. 2021. https://doi.org/10.1002/cmdc.202100291
    DORA PSI
  • Müller MC, Wagner T
    The oxoglutarate binding site and regulatory mechanism are conserved in ammonium transporter inhibitors glnks from Methanococcales
    International Journal of Molecular Sciences. 2021; 22(16): 8631 (16 pp.). https://doi.org/10.3390/ijms22168631
    DORA PSI
  • Nielsen AL, Rajabi N, Kudo N, Lundø K, Moreno-Yruela C, Bæk M, et al.
    Mechanism-based inhibitors of SIRT2: structure-activity relationship, X-ray structures, target engagement, regulation of α-tubulin acetylation and inhibition of breast cancer cell migration
    RSC Chemical Biology. 2021; 2(2): 612-626. https://doi.org/10.1039/d0cb00036a
    DORA PSI
  • Nilvebrant J, Ereño-Orbea J, Gorelik M, Julian MC, Tessier PM, Julien JP, et al.
    Systematic engineering of optimized autonomous heavy-chain variable domains
    Journal of Molecular Biology. 2021; 433(21): 167241 (18 pp.). https://doi.org/10.1016/j.jmb.2021.167241
    DORA PSI
  • Ostertag E, Zheng L, Broger K, Stehle T, Li S-M, Zocher G
    Reprogramming substrate and catalytic promiscuity of tryptophan prenyltransferases
    Journal of Molecular Biology. 2021; 433(2): 166726 (14 pp.). https://doi.org/10.1016/j.jmb.2020.11.025
    DORA PSI
  • Palmerini V, Monzani S, Laurichesse Q, Loudhaief R, Mari S, Cecatiello V, et al.
    Drosophila TNFRs Grindelwald and Wengen bind Eiger with different affinities and promote distinct cellular functions
    Nature Communications. 2021; 12(1): 2070 (12 pp.). https://doi.org/10.1038/s41467-021-22080-9
    DORA PSI
  • Persson BD, John L, Rafie K, Strebl M, Frängsmyr L, Ballmann MZ, et al.
    Human species D adenovirus hexon capsid protein mediates cell entry through a direct interaction with CD46
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2021; 118(3): e2020732118 (8 pp.). https://doi.org/10.1073/pnas.2020732118
    DORA PSI
  • Pipercevic J, Jakob RP, Righetto RD, Goldie KN, Stahlberg H, Maier T, et al.
    Identification of a Dps contamination in Mitomycin-C–induced expression of Colicin Ia
    Biochimica et Biophysica Acta: Biomembranes. 2021; 1863(7): 183607 (9 pp.). https://doi.org/10.1016/j.bbamem.2021.183607
    DORA PSI
  • Podolec R, Lau K, Wagnon TB, Hothorn M, Ulm R
    A constitutively monomeric UVR8 photoreceptor confers enhanced UV-B photomorphogenesis
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2021; 118(6): e2017284118 (10 pp.). https://doi.org/10.1073/pnas.2017284118
    DORA PSI
  • Polimeno L, Lerario G, De Giorgi M, De Marco L, Dominici L, Todisco F, et al.
    Tuning of the Berry curvature in 2D perovskite polaritons
    Nature Nanotechnology. 2021; 16: 1349-1354. https://doi.org/10.1038/s41565-021-00977-2
    DORA PSI
  • Pott M, Tinzl M, Hayashi T, Ota Y, Dunkelmann D, Mittl PRE, et al.
    Noncanonical heme ligands steer carbene transfer reactivity in an artificial metalloenzyme
    Angewandte Chemie International Edition. 2021; 60(27): 15063-15068. https://doi.org/10.1002/anie.202103437
    DORA PSI
  • Qiu H, Ali Z, Bowlan J, Caldwell R, Gardberg A, Glaser N, et al.
    Discovery of covalent bruton's tyrosine kinase inhibitors with decreased CYP2C8 inhibitory activity
    ChemMedChem. 2021; 16(24): 3653-3662. https://doi.org/10.1002/cmdc.202100453
    DORA PSI
  • Querques I, Schmitz M, Oberli S, Chanez C, Jinek M
    Target site selection and remodelling by type V CRISPR-transposon systems
    Nature. 2021; 599(7885): 497-502. https://doi.org/10.1038/s41586-021-04030-z
    DORA PSI
  • Ramharter J, Kessler D, Ettmayer P, Hofmann MH, Gerstberger T, Gmachl M, et al.
    One atom makes all the difference: Getting a foot in the door between SOS1 and KRAS
    Journal of Medicinal Chemistry. 2021; 64(10): 6569-6580. https://doi.org/10.1021/acs.jmedchem.0c01949
    DORA PSI
  • Ramos-Morales E, Bayam E, Del-Pozo-Rodríguez J, Salinas-Giegé T, Marek M, Tilly P, et al.
    The structure of the mouse ADAT2/ADAT3 complex reveals the molecular basis for mammalian tRNA wobble adenosine-to-inosine deamination
    Nucleic Acids Research. 2021; 49(11): 6529-6548. https://doi.org/10.1093/nar/gkab436
    DORA PSI
  • Ried MK, Wild R, Zhu J, Pipercevic J, Sturm K, Broger L, et al.
    Inositol pyrophosphates promote the interaction of SPX domains with the coiled-coil motif of PHR transcription factors to regulate plant phosphate homeostasis
    Nature Communications. 2021; 12: 348 (13 pp.). https://doi.org/10.1038/s41467-020-20681-4
    DORA PSI
  • Rohde M, Laun K, Zebger I, Stripp ST, Einsle O
    Two ligand-binding sites in CO-reducing V nitrogenase reveal a general mechanistic principle
    Science Advances. 2021; 7(22): eabg4474 (8 pp.). https://doi.org/10.1126/sciadv.abg4474
    DORA PSI
  • Romero-Romero S, Costas M, Silva Manzano D-A, Kordes S, Rojas-Ortega E, Tapia C, et al.
    The stability landscape of de novo TIM barrels explored by a modular design approach
    Journal of Molecular Biology. 2021; 433(18): 167153 (20 pp.). https://doi.org/10.1016/j.jmb.2021.167153
    DORA PSI
  • Ruegenberg S, Mayr FAMC, Atanassov I, Baumann U, Denzel MS
    Protein kinase A controls the hexosamine pathway by tuning the feedback inhibition of GFAT-1
    Nature Communications. 2021; 12: 2176 (14 pp.). https://doi.org/10.1038/s41467-021-22320-y
    DORA PSI
  • Ryan MD, Parkes AL, Corbett D, Dickie AP, Southey M, Andersen OA, et al.
    Discovery of novel UDP-N-acetylglucosamine acyltransferase (LpxA) inhibitors with activity against Pseudomonas aeruginosa
    Journal of Medicinal Chemistry. 2021; 64(19): 14377-14425. https://doi.org/10.1021/acs.jmedchem.1c00888
    DORA PSI
  • Röhrig UF, Majjigapu SR, Reynaud A, Pojer F, Dilek N, Reichenbach P, et al.
    Azole-based indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors
    Journal of Medicinal Chemistry. 2021; 64(4): 2205-2227. https://doi.org/10.1021/acs.jmedchem.0c01968
    DORA PSI
  • Sartor P, Denkhaus L, Gerhardt S, Einsle O, Fetzner S
    Structural basis of O-methylation of (2-heptyl-)1-hydroxyquinolin-4(1H)-one and related compounds by the heterocyclic toxin methyltransferase Rv0560c of Mycobacterium tuberculosis
    Journal of Structural Biology. 2021; 213(4): 107794 (10 pp.). https://doi.org/10.1016/j.jsb.2021.107794
    DORA PSI
  • Schenkmayerova A, Pinto GP, Toul M, Marek M, Hernychova L, Planas-Iglesias J, et al.
    Engineering the protein dynamics of an ancestral luciferase
    Nature Communications. 2021; 12(1): 3616 (16 pp.). https://doi.org/10.1038/s41467-021-23450-z
    DORA PSI
  • Schmitz RA, Picone N, Singer H, Dietl A, Seifert K-A, Pol A, et al.
    Neodymium as metal cofactor for biological methanol oxidation: structure and kinetics of an XoxF1-Type methanol dehydrogenase
    mBio. 2021; 12(5): e01708 (14 pp.). https://doi.org/10.1128/mBio.01708-21
    DORA PSI
  • Schnitzler A, Niefind K
    Structural basis for the design of bisubstrate inhibitors of protein kinase CK2 provided by complex structures with the substrate-competitive inhibitor heparin
    European Journal of Medicinal Chemistry. 2021; 214: 113223 (9 pp.). https://doi.org/10.1016/j.ejmech.2021.113223
    DORA PSI
  • Schultenkämper K, Gütle DD, López MG, Keller LB, Zhang L, Einsle O, et al.
    Interrogating the role of the two distinct fructose-bisphosphate aldolases of Bacillus methanolicus by site-directed mutagenesis of key amino acids and gene repression by CRISPR interference
    Frontiers in Microbiology. 2021; 12: 669220 (15 pp.). https://doi.org/10.3389/fmicb.2021.669220
    DORA PSI
  • Schäker-Hübner L, Warstat R, Ahlert H, Mishra P, Kraft FB, Schliehe-Diecks J, et al.
    4-acyl pyrrole capped HDAC inhibitors: a new scaffold for hybrid inhibitors of BET proteins and histone deacetylases as antileukemia drug leads
    Journal of Medicinal Chemistry. 2021; 64(19): 14620-14646. https://doi.org/10.1021/acs.jmedchem.1c01119
    DORA PSI
  • Shui S, Gainza P, Scheller L, Yang C, Kurumida Y, Rosset S, et al.
    A rational blueprint for the design of chemically-controlled protein switches
    Nature Communications. 2021; 12(1): 5754 (12 pp.). https://doi.org/10.1038/s41467-021-25735-9
    DORA PSI
  • Shyp V, Dubey BN, Böhm R, Hartl J, Nesper J, Vorholt JA, et al.
    Reciprocal growth control by competitive binding of nucleotide second messengers to a metabolic switch in Caulobacter crescentus
    Nature Microbiology. 2021; 6(1): 59-72. https://doi.org/10.1038/s41564-020-00809-4
    DORA PSI
  • Signor L, Paris T, Mas C, Picard A, Lutfalla G, Boeri Erba E, et al.
    Divalent cations influence the dimerization mode of murine S100A9 protein by modulating its disulfide bond pattern
    Journal of Structural Biology. 2021; 213(1): 107689 (16 pp.). https://doi.org/10.1016/j.jsb.2020.107689
    DORA PSI
  • Simeth NA, Kinateder T, Rajendran C, Nazet J, Merkl R, Sterner R, et al.
    Towards photochromic azobenzene-based inhibitors for tryptophan synthase
    Chemistry: A European Journal. 2021; 27(7): 2439-2451. https://doi.org/10.1002/chem.202004061
    DORA PSI
  • Soh Y-M, Basquin J, Gruber S
    A rod conformation of the Pyrococcus furiosus Rad50 coiled coil
    Proteins. 2021; 89(2): 251-255. https://doi.org/10.1002/prot.26005
    DORA PSI
  • Stein A, Chen D, Igareta NV, Cotelle Y, Rebelein JG, Ward TR
    A dual anchoring strategy for the directed evolution of improved artificial transfer hydrogenases based on carbonic anhydrase
    ACS Central Science. 2021; 7(11): 1874-1884. https://doi.org/10.1021/acscentsci.1c00825
    DORA PSI
  • Stronczek C, Lange S, Bullard B, Wolniak S, Börgeson E, Mayans O, et al.
    The N2A region of titin has a unique structural configuration
    Journal of General Physiology. 2021; 153(7): e202012766 (11 pp.). https://doi.org/10.1085/jgp.202012766
    DORA PSI
  • Stöger B, Krüger H, Weil M
    Mg(H2O)2[TeO2(OH)4]: a polytypic structure with a two-mode disordered stacking arrangement
    Acta Crystallographica Section B: Structural Science, Crystal Engineering and Materials. 2021; 77: (19 pp.). https://doi.org/10.1107/S2052520621006223
    DORA PSI
  • Sutanto F, Shaabani S, Oerlemans R, Eris D, Patil P, Hadian M, et al.
    Combining high-throughput synthesis and high-throughput protein crystallography for accelerated hit identification
    Angewandte Chemie International Edition. 2021; 60(33): 18231-18239. https://doi.org/10.1002/anie.202105584
    DORA PSI
  • Tam H-K, Foong WE, Oswald C, Herrmann A, Zeng H, Pos KM
    Allosteric drug transport mechanism of multidrug transporter AcrB
    Nature Communications. 2021; 12(1): 3889 (10 pp.). https://doi.org/10.1038/s41467-021-24151-3
    DORA PSI
  • Teixeira RD, Holzschuh F, Schirmer T
    Activation mechanism of a small prototypic Rec-GGDEF diguanylate cyclase
    Nature Communications. 2021; 12(1): 2162 (15 pp.). https://doi.org/10.1038/s41467-021-22492-7
    DORA PSI
  • Tesch R, Rak M, Raab M, Berger LM, Kronenberger T, Joerger AC, et al.
    Structure-based design of selective salt-inducible kinase inhibitors
    Journal of Medicinal Chemistry. 2021; 64(12): 8142-8160. https://doi.org/10.1021/acs.jmedchem.0c02144
    DORA PSI
  • Wagner TR, Ostertag E, Kaiser PD, Gramlich M, Ruetalo N, Junker D, et al.
    NeutrobodyPlex—monitoring SARS-CoV-2 neutralizing immune responses using nanobodies
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