Publications

PDB structures measured at X06DA

Recent publications are listed below. For an extensive overview we kindly refer you to our publication repository DORA

  • Arnold FM, Weber MS, Gonda I, Gallenito MJ, Adenau S, Egloff P, et al.
    The ABC exporter IrtAB imports and reduces mycobacterial siderophores
    Nature. 2020; 580(7803): 413-417. https://doi.org/10.1038/s41586-020-2136-9
    DORA PSI
  • Bedi RK, Huang D, Wiedmer L, Li Y, Dolbois A, Wojdyla JA, et al.
    Selectively disrupting m6A-dependent protein-RNA interactions with fragments
    ACS Chemical Biology. 2020; 15(3): 618-625. https://doi.org/10.1021/acschembio.9b00894
    DORA PSI
  • Binas O, Tants J-N, Peter SA, Janowski R, Davydova E, Braun J, et al.
    Structural basis for the recognition of transiently structured AU-rich elements by Roquin
    Nucleic Acids Research. 2020. https://doi.org/10.1093/nar/gkaa465
    DORA PSI
  • Boon M, De Zitter E, De Smet J, Wagemans J, Voet M, Pennemann FL, et al.
    'Drc', a structurally novel ssDNA-binding transcription regulator of N4-related bacterial viruses
    Nucleic Acids Research. 2020; 48(1): 445-459. https://doi.org/10.1093/nar/gkz1048
    DORA PSI
  • Brams M, Govaerts C, Kambara K, Price KL, Spurny R, Gharpure A, et al.
    Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT3 receptor via a common vestibule site
    eLife. 2020; 9: e51511 (19 pp.). https://doi.org/10.7554/eLife.51511
    DORA PSI
  • Busetto V, Barbosa I, Basquin J, Marquenet É, Hocq R, Hennion M, et al.
    Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes
    Nucleic Acids Research. 2020. https://doi.org/10.1093/nar/gkaa267
    DORA PSI
  • Chiniadis L, Bratsos I, Bethanis K, Karpusas M, Giastas P, Papakyriakou A
    High-resolution crystal structures of a "half sandwich"-type Ru(II) coordination compound bound to hen egg-white lysozyme and proteinase K
    Journal of Biological Inorganic Chemistry. 2020. https://doi.org/10.1007/s00775-020-01786-z
    DORA PSI
  • Cinquino M, Polimeno L, Lerario G, De Giorgi M, Moliterni A, Olieric V, et al.
    One-step synthesis at room temperature of low dimensional perovskite single crystals with high optical quality
    Journal of Luminescence. 2020; 221: 117079 (8 pp.). https://doi.org/10.1016/j.jlumin.2020.117079
    DORA PSI
  • Cottee MA, Letham SC, Young GR, Stoye JP, Taylor IA
    Structure of Drosophila melanogaster ARC1 reveals a repurposed molecule with characteristics of retroviral Gag
    Science Advances. 2020; 6(1): eaay6354 (12 pp.). https://doi.org/10.1126/sciadv.aay6354
    DORA PSI
  • Draxler SW, Bauer M, Eickmeier C, Nadal S, Nar H, Rangel Rojas D, et al.
    Hybrid screening approach for very small fragments: X-ray and computational screening on FKBP51
    Journal of Medicinal Chemistry. 2020; 63(11): 5856-5864. https://doi.org/10.1021/acs.jmedchem.0c00120
    DORA PSI
  • Duarte DP, Lamontanara AJ, La Sala G, Jeong S, Sohn Y-K, Panjkovich A, et al.
    Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms
    Nature Communications. 2020; 11(1): 2319 (15 pp.). https://doi.org/10.1038/s41467-020-16128-5
    DORA PSI
  • Dubey BN, Agustoni E, Böhm R, Kaczmarczyk A, Mangia F, von Arx C, et al.
    Hybrid histidine kinase activation by cyclic di-GMP-mediated domain liberation
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2020; 117(2): 1000-1008. https://doi.org/10.1073/pnas.1911427117
    DORA PSI
  • Ecsédi P, Gógl G, Hóf H, Kiss B, Harmat V, Nyitray L
    Structure determination of the transactivation domain of p53 in complex with S100A4 using annexin A2 as a crystallization chaperone
    Structure. 2020. https://doi.org/10.1016/j.str.2020.05.001
    DORA PSI
  • Ernst P, Zosel F, Reichen C, Nettels D, Schuler B, Plückthun A
    Structure-guided design of a peptide lock for modular peptide binders
    ACS Chemical Biology. 2020; 15(2): 457-468. https://doi.org/10.1021/acschembio.9b00928
    DORA PSI
  • Gao X, Zhu K, Wojdyl JA, Chen P, Qin B, Li Z, et al.
    Crystal structure of the NS3-like helicase from Alongshan virus
    IUCrJ. 2020; 7(3): 375-382. https://doi.org/10.1107/S2052252520003632
    DORA PSI
  • Garcia-Doval C, Schwede F, Berk C, Rostøl JT, Niewoehner O, Tejero O, et al.
    Activation and self-inactivation mechanisms of the cyclic oligoadenylate-dependent CRISPR ribonuclease Csm6
    Nature Communications. 2020; 11(1): 1596 (9 pp.). https://doi.org/10.1038/s41467-020-15334-5
    DORA PSI
  • Gogl G, Jane P, Caillet-Saguy C, Kostmann C, Bich G, Cousido-Siah A, et al.
    Dual specificity PDZ- and 14-3-3-binding motifs: a structural and interactomics study
    Structure. 2020. https://doi.org/10.1016/j.str.2020.03.010
    DORA PSI
  • Hanke T, Cheung S-Y, Kilu W, Heering J, Ni X, Planz V, et al.
    A selective modulator of peroxisome proliferator-activated receptor γ with an unprecedented binding mode
    Journal of Medicinal Chemistry. 2020; 63(9): 4555-4561. https://doi.org/10.1021/acs.jmedchem.9b01786
    DORA PSI
  • Heddi B, Cheong VV, Schmitt E, Mechulam Y, Phan AT
    Recognition of different base tetrads by RHAU (DHX36): X-ray crystal structure of the G4 recognition motif bound to the 3′-end tetrad of a DNA G-quadruplex
    Journal of Structural Biology. 2020; 209(1): 107399 (8 pp.). https://doi.org/10.1016/j.jsb.2019.10.001
    DORA PSI
  • Hochstrasser R, Hutter CAJ, Arnold FM, Bärlocher K, Seeger MA, Hilbi H
    The structure of the Legionella response regulator LqsR reveals amino acids critical for phosphorylation and dimerization
    Molecular Microbiology. 2020. https://doi.org/10.1111/mmi.14477
    DORA PSI
  • Johansson E, Nielsen AD, Demuth H, Wiberg C, Schjødt CB, Huang T, et al.
    Identification of binding sites on human serum albumin for somapacitan, a long-acting growth hormone derivative
    Biochemistry. 2020; 59(14): 1410-1419. https://doi.org/10.1021/acs.biochem.0c00019
    DORA PSI
  • Juroszek R, Krüger B, Galuskina I, Krüger H, Vapnik Y, Galuskin E
    Siwaqaite, Ca6Al2(CrO4)3(OH)12·26H2O, a new mineral of the ettringite group from the pyrometamorphic Daba-Siwaqa complex, Jordan
    American Mineralogist. 2020; 105(3): 409-421. https://doi.org/10.2138/am-2020-7208
    DORA PSI
  • Koiwai K, Inaba K, Morohashi K, Enya S, Arai R, Kojima H, et al.
    An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo
    Journal of Biological Chemistry. 2020; 295(20): 7154-7167. https://doi.org/10.1074/jbc.RA119.011463
    DORA PSI
  • Kong X-D, Moriya J, Carle V, Pojer F, Abriata LA, Deyle K, et al.
    De novo development of proteolytically resistant therapeutic peptides for oral administration
    Nature Biomedical Engineering. 2020; 4(5): 560-571. https://doi.org/10.1038/s41551-020-0556-3
    DORA PSI
  • Kries H, Bloch JS, Bunzel HA, Pinkas DM, Hilvert D
    Contribution of oxyanion stabilization to kemp eliminase efficiency
    ACS Catalysis. 2020; 10(8): 4460-4464. https://doi.org/10.1021/acscatal.0c00575
    DORA PSI
  • Larson ET, Brennan DL, Hickey ER, Ganesan R, Kroe‐Barrett R, Farrow NA
    X-ray crystal structure localizes the mechanism of inhibition of an IL-36R antagonist monoclonal antibody to interaction with Ig1 and Ig2 extra cellular domains
    Protein Science. 2020. https://doi.org/10.1002/pro.3862
    DORA PSI
  • Ma B, Lucas B, Capacci A, Lin EY-S, Jones JH, Dechantsreiter M, et al.
    Design, synthesis and identification of novel, orally bioavailable non-covalent Nrf2 activators
    Bioorganic and Medicinal Chemistry Letters. 2020; 30(4): 126852 (8 pp.). https://doi.org/10.1016/j.bmcl.2019.126852
    DORA PSI
  • Marasco M, Berteotti A, Weyershaeuser J, Thorausch N, Sikorska J, Krausze J, et al.
    Molecular mechanism of SHP2 activation by PD-1 stimulation
    Science Advances. 2020; 6(5): eaay4458 (15 pp.). https://doi.org/10.1126/sciadv.aay4458
    DORA PSI
  • Marcotte DJ, Spilker KA, Wen D, Hesson T, Patterson TA, Rajesh Kumar P, et al.
    The crystal structure of the catalytic domain of tau tubulin kinase 2 in complex with a small-molecule inhibitor
    Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 2020; 76: 103-108. https://doi.org/10.1107/S2053230X2000031X
    DORA PSI
  • Martiel I, Buntschu D, Meier N, Gobbo A, Panepucci E, Schneider R, et al.
    The TELL automatic sample changer for macromolecular crystallography
    Journal of Synchrotron Radiation. 2020; 27: 860-863. https://doi.org/10.1107/S1600577520002416
    DORA PSI
  • Moussu S, Broyart C, Santos-Fernandez G, Augustin S, Wehrle S, Grossniklaus U, et al.
    Structural basis for recognition of RALF peptides by LRX proteins during pollen tube growth
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2020; 117(13): 7494-7503. https://doi.org/10.1073/pnas.2000100117
    DORA PSI
  • Nakamura R, Hikita M, Ogawa S, Takahashi Y, Fujishiro T
    Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes
    FEBS Journal. 2020; 287(6): 1138-1154. https://doi.org/10.1111/febs.15081
    DORA PSI
  • Nicoll CR, Bailleul G, Fiorentini F, Mascotti ML, Fraaije MW, Mattevi A
    Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs
    Nature Structural and Molecular Biology. 2020; 27(1): 14-24. https://doi.org/10.1038/s41594-019-0347-2
    DORA PSI
  • Okuda S, Fujita S, Moretti A, Hohmann U, Doblas VG, Ma Y, et al.
    Molecular mechanism for the recognition of sequencedivergent CIF peptides by the plant receptor kinases GSO1/SGN3 and GSO2
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2020; 117(5): 2693-2703. https://doi.org/10.1073/pnas.1911553117
    DORA PSI
  • Parker BW, Gogl G, Bálint M, Hetényi C, Reményi A, Weiss EL
    Ndr/Lats kinases bind specific mob-family coactivators through a conserved and modular interface
    Biochemistry. 2020; 59(17): 1688-1700. https://doi.org/10.1021/acs.biochem.9b01096
    DORA PSI
  • Pietsch M, Viht K, Schnitzler A, Ekambaram R, Steinkrüger M, Enkvist E, et al.
    Unexpected CK2β-antagonistic functionality of bisubstrate inhibitors targeting protein kinase CK2
    Bioorganic Chemistry. 2020; 96: 103608 (8 pp.). https://doi.org/10.1016/j.bioorg.2020.103608
    DORA PSI
  • Rajan S, Jang Y, Kim C-H, Kim W, Toh HT, Jeon J, et al.
    PGE1 and PGA1 bind to Nurr1 and activate its transcriptional function
    Nature Chemical Biology. 2020. https://doi.org/10.1038/s41589-020-0553-6
    DORA PSI
  • Romussi A, Cappa A, Vianello P, Brambillasca S, Cera MR, Dal Zuffo R, et al.
    Discovery of reversible inhibitors of KDM1A efficacious in acute myeloid leukemia models
    ACS Medicinal Chemistry Letters. 2020; 11(5): 754-759. https://doi.org/10.1021/acsmedchemlett.9b00604
    DORA PSI
  • Ruegenberg S, Horn M, Pichlo C, Allmeroth K, Baumann U, Denzel MS
    Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis
    Nature Communications. 2020; 11(1): 687 (16 pp.). https://doi.org/10.1038/s41467-020-14524-5
    DORA PSI
  • Sabath K, Stäubli ML, Marti S, Leitner A, Moes M, Jonas S
    INTS10-INTS13-INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module
    Nature Communications. 2020; 11(1): 3422 (16 pp.). https://doi.org/10.1038/s41467-020-17232-2
    DORA PSI
  • Savino S, Jensen S, Terwisscha van Scheltinga A, Fraaije MW
    Analysis of the structure and substrate scope of chitooligosaccharide oxidase reveals high affinity for C2-modified glucosamines
    FEBS Letters. 2020. https://doi.org/10.1002/1873-3468.13854
    DORA PSI
  • Sesterhenn F, Yang C, Bonet J, Cramer JT, Wen X, Wang Y, et al.
    De novo protein design enables the precise induction of RSV-neutralizing antibodies
    Science. 2020; 368(6492): eaay5051 (10 pp.). https://doi.org/10.1126/science.aay5051
    DORA PSI
  • Softley CA, Zak KM, Bostock MJ, Fino R, Zhou RX, Kolonko M, et al.
    Structure and molecular recognition mechanism of IMP-13 metallo-β-lactamase
    Antimicrobial Agents and Chemotherapy. 2020; 64(6): e00123-20 (20 pp.). https://doi.org/10.1128/AAC.00123-20
    DORA PSI
  • Soman A, Liew CW, Teo HL, Berezhnoy NV, Olieric V, Korolev N, et al.
    The human telomeric nucleosome displays distinct structural and dynamic properties
    Nucleic Acids Research. 2020; 48(10): 5383-5396. https://doi.org/10.1093/nar/gkaa289
    DORA PSI
  • Studer MK, Ivanovic L, Weber ME, Marti S, Jonas S
    Structural basis for DEAH-helicase activation by G-patch proteins
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2020; 117(13): 7159-7170. https://doi.org/10.1073/pnas.1913880117
    DORA PSI
  • Surivet J-P, Panchaud P, Specklin J-L, Diethelm S, Blumstein A-C, Gauvin J-C, et al.
    Discovery of novel inhibitors of LpxC displaying potent in vitro activity against Gram-negative bacteria
    Journal of Medicinal Chemistry. 2020; 63(1): 66-87. https://doi.org/10.1021/acs.jmedchem.9b01604
    DORA PSI
  • Tomassi S, Pfahler J, Mautone N, Rovere A, Esposito C, Passeri D, et al.
    From PARP1 to TNKS2 inhibition: a structure-based approach
    ACS Medicinal Chemistry Letters. 2020; 11(5): 862-868. https://doi.org/10.1021/acsmedchemlett.9b00654
    DORA PSI
  • Traczyk A, Liew CW, Gill DJ, Rhodes D
    Structural basis of G-quadruplex DNA recognition by the yeast telomeric protein Rap1
    Nucleic Acids Research. 2020; 48(8): 4562-4571. https://doi.org/10.1093/nar/gkaa171
    DORA PSI
  • Vettraino C, Peracchi A, Donini S, Parisinia E
    Structural characterization of human O-phosphoethanolamine phospho-lyase
    Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 2020; 76: 160-167. https://doi.org/10.1107/S2053230X20002988
    DORA PSI
  • Welte H, Zhou T, Mihajlenko X, Mayans O, Kovermann M
    What does fluorine do to a protein? Thermodynamic, and highly-resolved structural insights into fluorine-labelled variants of the cold shock protein
    Scientific Reports. 2020; 10(1): 2640 (12 pp.). https://doi.org/10.1038/s41598-020-59446-w
    DORA PSI
  • Wenskowsky L, Wagner M, Reusch J, Schreuder H, Matter H, Opatz T, et al.
    Resolving binding events on the multifunctional human serum albumin
    ChemMedChem. 2020; 15(9): 738-743. https://doi.org/10.1002/cmdc.202000069
    DORA PSI
  • White C, McGowan MA, Zhou H, Sciammetta N, Fradera X, Lim J, et al.
    Strategic incorporation of polarity in heme-displacing inhibitors of indoleamine-2,3-dioxygenase-1 (IDO1)
    ACS Medicinal Chemistry Letters. 2020; 11(4): 550-557. https://doi.org/10.1021/acsmedchemlett.0c00010
    DORA PSI
  • Xin Z, Himmelbauer MK, Jones JH, Enyedy I, Gilfillan R, Hesson T, et al.
    Discovery of CNS-penetrant apoptosis signal-regulating kinase 1 (ASK1) inhibitors
    ACS Medicinal Chemistry Letters. 2020; 11(4): 485-490. https://doi.org/10.1021/acsmedchemlett.9b00611
    DORA PSI
  • Yu X, Gao X, Zhu K, Yin H, Mao X, Wojdyla JA, et al.
    Characterization of a toxin-antitoxin system in Mycobacterium tuberculosis suggests neutralization by phosphorylation as the antitoxicity mechanism
    Communications Biology. 2020; 3(1): 216 (15 pp.). https://doi.org/10.1038/s42003-020-0941-1
    DORA PSI
  • Zender M, Witzgall F, Kiefer A, Kirsch B, Maurer CK, Kany AM, et al.
    Flexible fragment growing boosts potency of quorum-sensing inhibitors against Pseudomonas aeruginosa virulence
    ChemMedChem. 2020; 15(2): 188-194. https://doi.org/10.1002/cmdc.201900621
    DORA PSI
  • Abskharon R, Wang F, Wohlkonig A, Ruan J, Soror S, Giachin G, et al.
    Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion
    PLoS Pathogens. 2019; 15(12): e1008139 (21 pp.). https://doi.org/10.1371/journal.ppat.1008139
    DORA PSI
  • Akichika S, Hirano S, Shichino Y, Suzuki T, Nishimasu H, Ishitani R, et al.
    Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase
    Science. 2019; 363(6423): eaav0080 (7 pp.). https://doi.org/10.1126/science.aav0080
    DORA PSI
  • Andreou A, Giastas P, Arnaouteli S, Tzanodaskalaki M, Tzartos SJ, Bethanis K, et al.
    The putative polysaccharide deacetylase Ba0331: cloning, expression, crystallization and structure determination
    Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 2019; 75(4): 312-320. https://doi.org/10.1107/S2053230X19001766
    DORA PSI
  • André C, Martiel I, Wolff P, Landolfo M, Lorber B, Silva da Veiga C, et al.
    Interaction of a model peptide on gram negative and gram positive bacterial sliding clamps
    ACS Infectious Diseases. 2019; 5: 1022-1034. https://doi.org/10.1021/acsinfecdis.9b00089
    DORA PSI
  • Apel A-K, Cheng RKY, Tautermann CS, Brauchle M, Huang C-Y, Pautsch A, et al.
    Crystal structure of CC chemokine receptor 2A in complex with an orthosteric antagonist provides insights for the design of selective antagonists
    Structure. 2019; 27(3): 427-438.e5. https://doi.org/10.1016/j.str.2018.10.027
    DORA PSI
  • Bachmaier S, Volpato Santos Y, Kramer S, Githure GB, Klöckner T, Pepperl J, et al.
    Nucleoside analogue activators of cyclic AMP-independent protein kinase A of Trypanosoma
    Nature Communications. 2019; 10(1): 1421 (14 pp.). https://doi.org/10.1038/s41467-019-09338-z
    DORA PSI
  • Baeriswyl S, Javor S, Stocker A, Darbre T, Reymond J-L
    X-Ray crystal structure of a second-generation peptide dendrimer in complex with Pseudomonas aeruginosa lectin LecB
    Helvetica Chimica Acta. 2019; 102(9): e1900178 (10 pp.). https://doi.org/10.1002/hlca.201900178
    DORA PSI
  • Baeriswyl S, Gan B-H, Siriwardena TN, Visini R, Robadey M, Javor S, et al.
    X-ray crystal structures of short antimicrobial peptides as Pseudomonas aeruginosa lectin B complexes
    ACS Chemical Biology. 2019; 14(4): 758-766. https://doi.org/10.1021/acschembio.9b00047
    DORA PSI
  • Baier M, Rustmeier NH, Harr J, Cyrus N, Reiss GJ, Grafmüller A, et al.
    Divalent sialylated precision glycooligomers binding to polyomaviruses and the effect of different linkers
    Macromolecular Bioscience. 2019; 19(5): 1800426 (7 pp.). https://doi.org/10.1002/mabi.201800426
    DORA PSI
  • Basu S, Olieric V, Leonarski F, Matsugaki N, Kawano Y, Takashi T, et al.
    Long-wavelength native-SAD phasing: opportunities and challenges
    IUCrJ. 2019; 6(3): 1-14. https://doi.org/10.1107/S2052252519002756
    DORA PSI
  • Basu S, Finke A, Vera L, Wang M, Olieric V
    Making routine native SAD a reality: lessons from beamline X06DA at the Swiss Light Source
    Acta Crystallographica Section D: Structural Biology. 2019; 75(3): 262-271. https://doi.org/10.1107/S2059798319003103
    DORA PSI
  • Batchelor LK, De Falco L, von Erlach T, Sharma D, Adhireksan Z, Roethlisberger U, et al.
    Crosslinking allosteric sites on the nucleosome
    Angewandte Chemie International Edition. 2019; 58(44): 15660-15664. https://doi.org/10.1002/anie.201906423
    DORA PSI
  • Belorusova AY, Evertsson E, Hovdal D, Sandmark J, Bratt E, Maxvall I, et al.
    Structural analysis identifies an escape route from the adverse lipogenic effects of liver X receptor ligands
    Communications Biology. 2019; 2(1): 431 (13 pp.). https://doi.org/10.1038/s42003-019-0675-0
    DORA PSI
  • Bergner A, Cockcroft X, Fischer G, Gollner A, Hela W, Kousek R, et al.
    KRAS binders hidden in nature
    Chemistry: A European Journal. 2019; 25(52): 12037-12041. https://doi.org/10.1002/chem.201902810
    DORA PSI
  • Boneberg FM, Brandmann T, Kobel L, van den Heuvel J, Bargsten K, Bammert L, et al.
    Molecular mechanism of the RNA helicase DHX37 and its activation by UTP14A in ribosome biogenesis
    RNA. 2019; 25(6): 685-701. https://doi.org/10.1261/rna.069609.118
    DORA PSI
  • Brindisi M, Ulivieri C, Alfano G, Gemma S, de Asís Balaguer F, Khan T, et al.
    Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents
    European Journal of Medicinal Chemistry. 2019; 162: 290-320. https://doi.org/10.1016/j.ejmech.2018.11.004
    DORA PSI
  • Bunzel HA, Kries H, Marchetti L, Zeymer C, Mittl PRE, Mulholland AJ, et al.
    Emergence of a negative activation heat capacity during evolution of a designed enzyme
    Journal of the American Chemical Society. 2019; 141(30): 11745-11748. https://doi.org/10.1021/jacs.9b02731
    DORA PSI
  • Böttcher J, Dilworth D, Reiser U, Neumüller RA, Schleicher M, Petronczki M, et al.
    Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3
    Nature Chemical Biology. 2019; 15(8): 822-829. https://doi.org/10.1038/s41589-019-0310-x
    DORA PSI
  • Castagna R, Donini S, Colnago P, Serafini A, Parisini E, Bertarelli C
    Biohybrid electrospun membrane for the filtration of ketoprofen drug from water
    ACS Omega. 2019; 4(8): 13270-13278. https://doi.org/10.1021/acsomega.9b01442
    DORA PSI
  • Chaikuad A, Koschade SE, Stolz A, Zivkovic K, Pohl C, Shaid S, et al.
    Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2)
    Biochemical Journal. 2019; 476(5): 875-887. https://doi.org/10.1042/BCJ20190038
    DORA PSI
  • Chen F, Lukat P, Iqbal AA, Saile K, Kaever V, van den Heuvel J, et al.
    Crystal structure of cis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2019; 116(41): 20644-20654. https://doi.org/10.1073/pnas.1908770116
    DORA PSI
  • Clarke DE, Noguchi H, Gryspeerdt J-LAG, De Feyter S, Voet ARD
    Artificial β-propeller protein-based hydrolases
    Chemical Communications. 2019; 55(60): 8880-8883. https://doi.org/10.1039/c9cc04388h
    DORA PSI
  • Costa NL, Hermann B, Fourmond V, Faustino MM, Teixeira M, Einsle O, et al.
    How thermophilic Gram-positive organisms perform extracellular electron transfer: characterization of the cell surface terminal reductase OcwA
    mBio. 2019; 10(4): e01210-19 (13 pp.). https://doi.org/10.1128/mBio.01210-19
    DORA PSI
  • Damm-Ganamet KL, Arora N, Becart S, Edwards JP, Lebsack AD, McAllister HM, et al.
    Accelerating lead identification by high throughput virtual screening: prospective case studies from the pharmaceutical industry
    Journal of Chemical Information and Modeling. 2019; 59(5): 2046-2062. https://doi.org/10.1021/acs.jcim.8b00941
    DORA PSI
  • Deshpande I, Keusch JJ, Challa K, Iesmantavicius V, Gasser SM, Gut H
    The Sir4 H-BRCT domain interacts with phospho-proteins to sequester and repress yeast heterochromatin
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