Publications

Recent publications are listed below. For an extensive overview we kindly refer you to our publication repository DORA

  • Atkinson SJ, Bagal SK, Argyrou A, Askin S, Cheung T, Chiarparin E, et al.
    Development of a series of pyrrolopyridone MAT2A inhibitors
    Journal of Medicinal Chemistry. 2024; 67(6): 4541-4559. https://doi.org/10.1021/acs.jmedchem.3c01860
    DORA PSI
  • Batchelor LK, De Falco L, Dyson PJ, Davey CA
    Viral peptide conjugates for metal-warhead delivery to chromatin
    RSC Advances. 2024; 14(13): 8718-8725. https://doi.org/10.1039/d4ra01617c
    DORA PSI
  • Compain G, Monsarrat C, Blagojevic J, Brillet K, Dumas P, Hammann P, et al.
    Peptide-based covalent inhibitors bearing mild electrophiles to target a conserved his residue of the bacterial sliding clamp
    JACS Au. 2024; 4(2): 432-440. https://doi.org/10.1021/jacsau.3c00572
    DORA PSI
  • Corbeski I, Vargas-Rosales PA, Bedi RK, Deng J, Coelho D, Braud E, et al.
    The catalytic mechanism of the RNA methyltransferase METTL3
    eLife. 2024; 12: RP92537 (27 pp.). https://doi.org/10.7554/eLife.92537
    DORA PSI
  • Fu C, Liu Y, Walt C, Rasheed S, Bader CD, Lukat P, et al.
    Elucidation of unusual biosynthesis and DnaN-targeting mode of action of potent anti-tuberculosis antibiotics Mycoplanecins
    Nature Communications. 2024; 15(1): 791 (13 pp.). https://doi.org/10.1038/s41467-024-44953-5
    DORA PSI
  • Hiller M, Diwo M, Wamp S, Gutsmann T, Lang C, Blankenfeldt W, et al.
    Structure–function relationships underpin disulfide loop cleavage-dependent activation of Legionella pneumophila lysophospholipase A PlaA
    Molecular Microbiology. 2024; 121(3): 497-512. https://doi.org/10.1111/mmi.15201
    DORA PSI
  • Jungfer K, Sigg A, Jinek M
    Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2
    Nucleic Acids Research. 2024; 52(1): 462-473. https://doi.org/10.1093/nar/gkad1102
    DORA PSI
  • Kjeldsen T, Andersen AS, Hubálek F, Johansson E, Kreiner FF, Schluckebier G, et al.
    Molecular engineering of insulin for recombinant expression in yeast
    Trends in Biotechnology. 2024; 42(4): 464-478. https://doi.org/10.1016/j.tibtech.2023.09.012
    DORA PSI
  • Mastria R, Riisnaes KJ, Bacon A, Leontis I, Lam HT, Alshehri MAS, et al.
    Real time and highly sensitive sub-wavelength 2D hybrid perovskite photodetectors
    Advanced Functional Materials. 2024. https://doi.org/10.1002/adfm.202401903
    DORA PSI
  • Meinhold S, Zdanowicz R, Giese C, Glockshuber R
    Dimerization of a 5-kDa domain defines the architecture of the 5-MDa gammaproteobacterial pyruvate dehydrogenase complex
    Science Advances. 2024; 10(6): eadj6358 (17 pp.). https://doi.org/10.1126/sciadv.adj6358
    DORA PSI
  • Müller MC, Lemaire ON, Kurth JM, Welte CU, Wagner T
    Differences in regulation mechanisms of glutamine synthetases from methanogenic archaea unveiled by structural investigations
    Communications Biology. 2024; 7(1): 111. https://doi.org/10.1038/s42003-023-05726-w
    DORA PSI
  • Nalivaiko EY, Vasseur CM, Seebeck FP
    Enzyme-catalyzed oxidative degradation of ergothioneine
    Angewandte Chemie International Edition. 2024; 63(8): e202318445 (8 pp.). https://doi.org/10.1002/anie.202318445
    DORA PSI
  • Ober VT, Githure GB, Volpato Santos Y, Becker S, Moya Munoz G, Basquin J, et al.
    Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens
    eLife. 2024; 12: RP91040 (33 pp.). https://doi.org/10.7554/eLife.91040
    DORA PSI
  • Adam S, Zheng D, Klein A, Volz C, Mullen W, Shirran SL, et al.
    Unusual peptide-binding proteins guide pyrroloindoline alkaloid formation in crocagin biosynthesis
    Nature Chemistry. 2023; 15(4): 560-568. https://doi.org/10.1038/s41557-023-01153-w
    DORA PSI
  • Alvarez HA, Cousido-Siah A, Espinosa YR, Podjarny A, Carlevaro CM, Howard E
    Lipid exchange in crystal-confined fatty acid binding proteins: X-ray evidence and molecular dynamics explanation
    Proteins. 2023; 91(11): 1525-1534. https://doi.org/10.1002/prot.26546
    DORA PSI
  • Anso I, Naegeli A, Cifuente JO, Orrantia A, Andersson E, Zenarruzabeitia O, et al.
    Turning universal O into rare Bombay type blood
    Nature Communications. 2023; 14(1): 1765 (16 pp.). https://doi.org/10.1038/s41467-023-37324-z
    DORA PSI
  • Arifi S, Marschner JA, Pollinger J, Isigkeit L, Heitel P, Kaiser A, et al.
    Targeting the alternative vitamin E metabolite binding site enables noncanonical PPARγ modulation
    Journal of the American Chemical Society. 2023; 145(27): 14802-14810. https://doi.org/10.1021/jacs.3c03417
    DORA PSI
  • Bashore FM, Marquez AB, Chaikuad A, Howell S, Dunn AS, Beltran AA, et al.
    Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis
    Scientific Reports. 2023; 13(1): 6118 (17 pp.). https://doi.org/10.1038/s41598-023-32854-4
    DORA PSI
  • Bedi RK, Huang D, Li Y, Caflisch A
    Structure-based design of inhibitors of the m6A-RNA writer enzyme METTL3
    ACS Bio & Med Chem Au. 2023; 3(4): 359-370. https://doi.org/10.1021/acsbiomedchemau.3c00023
    DORA PSI
  • Billiald P, Slater A, Welin M, Clark JC, Loyau S, Pugnière M, et al.
    Targeting platelet GPVI with glenzocimab: a novel mechanism for inhibition
    Blood Advances. 2023; 7(7): 1258-1268. https://doi.org/10.1182/bloodadvances.2022007863
    DORA PSI
  • Boiarska Z, Pérez-Peña H, Abel A-C, Marzullo P, Álvarez-Bernad B, Bonato F, et al.
    Maytansinol functionalization: towards useful probes for studying microtubule dynamics
    Chemistry: A European Journal. 2023; 29(5): e202203431 (12 pp.). https://doi.org/10.1002/chem.202203431
    DORA PSI
  • Brkic A, Leibundgut M, Jablonska J, Zanki V, Car Z, Petrovic Perokovic V, et al.
    Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif
    Nature Communications. 2023; 14(1): 5498 (12 pp.). https://doi.org/10.1038/s41467-023-41244-3
    DORA PSI
  • Bui TYH, De Zitter E, Moeyaert B, Pecqueur L, Srinivasu BY, Economou A, et al.
    Oxygen-induced chromophore degradation in the photoswitchable red fluorescent protein rsCherry
    International Journal of Biological Macromolecules. 2023; 239: 124179 (9 pp.). https://doi.org/10.1016/j.ijbiomac.2023.124179
    DORA PSI
  • Busch MR, Rajendran C, Sterner R
    Structural and functional characterization of the ureidoacrylate amidohydrolase RutB from Escherichia coli
    Biochemistry. 2023; 62(3): 863-872. https://doi.org/10.1021/acs.biochem.2c00640
    DORA PSI
  • Cadoux C, Ratcliff D, Maslać N, Gu W, Tsakoumagkos I, Hoogendoorn S, et al.
    Nitrogen fixation and hydrogen evolution by sterically encumbered Mo-nitrogenase
    JACS Au. 2023; 3(5): 1521-1533. https://doi.org/10.1021/jacsau.3c00165
    DORA PSI
  • Cadoux C, Maslać N, Di Luzio L, Ratcliff D, Gu W, Wagner T, et al.
    The mononuclear metal-binding site of Mo-nitrogenase is not required for activity
    JACS Au. 2023; 3(11): 2993-2999. https://doi.org/10.1021/jacsau.3c00567
    DORA PSI
  • Chandra M, Đaković S, Foti K, Zeelen JP, van Straaten M, Aresta-Branco F, et al.
    Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome
    PLoS Neglected Tropical Diseases. 2023; 17(2): e0011093 (18 pp.). https://doi.org/10.1371/journal.pntd.0011093
    DORA PSI
  • Chmelova K, Gao T, Polak M, Schenkmayerova A, Croll TI, Shaikh TR, et al.
    Multimeric structure of a subfamily III haloalkane dehalogenase‐like enzyme solved by combination of cryo‐EM and x‐ray crystallography
    Protein Science. 2023; 32(10): e4751 (22 pp.). https://doi.org/10.1002/pro.4751
    DORA PSI
  • De Simone M, Alvigini L, Alonso-Cotchico L, Brissos V, Caroli J, Lucas MF, et al.
    Rationally guided improvement of NOV1 dioxygenase for the conversion of lignin-derived isoeugenol to vanillin
    Biochemistry. 2023; 62(2): 419-428. https://doi.org/10.1021/acs.biochem.2c00168
    DORA PSI
  • Denkhaus L, Siffert F, Einsle O
    An unusual active site architecture in cytochrome c nitrite reductase NrfA-1 from Geobacter metallireducens
    FEMS Microbiology Letters. 2023; 370: 1-8. https://doi.org/10.1093/femsle/fnad068
    DORA PSI
  • Dubey BN, Shyp V, Fucile G, Sondermann H, Jenal U, Schirmer T
    Mutant structure of metabolic switch protein in complex with monomeric c-di-GMP reveals a potential mechanism of protein-mediated ligand dimerization
    Scientific Reports. 2023; 13(1): 2727 (13 pp.). https://doi.org/10.1038/s41598-023-29110-0
    DORA PSI
  • Díaz-Perlas C, Ricken B, Farrera-Soler L, Guschin D, Pojer F, Lau K, et al.
    High-affinity peptides developed against calprotectin and their application as synthetic ligands in diagnostic assays
    Nature Communications. 2023; 14(1): 2774 (14 pp.). https://doi.org/10.1038/s41467-023-38075-7
    DORA PSI
  • Dürvanger Z, Juhász T, Liliom K, Harmat V
    Structures of calmodulin–melittin complexes show multiple binding modes lacking classical anchoring interactions
    Journal of Biological Chemistry. 2023; 299(4): 104596 (15 pp.). https://doi.org/10.1016/j.jbc.2023.104596
    DORA PSI
  • Ebenhoch R, Bauer M, Romig H, Gottschling D, Kley JT, Heine N, et al.
    Crystal structures of human and mouse ketohexokinase provide a structural basis for species- and isoform-selective inhibitor design
    Acta Crystallographica Section D: Structural Biology. 2023; 79(10): 871-880. https://doi.org/10.1107/S2059798323006137
    DORA PSI
  • Eichenberger M, Schwander T, Hüppi S, Kreuzer J, Mittl PRE, Peccati F, et al.
    The catalytic role of glutathione transferases in heterologous anthocyanin biosynthesis
    Nature Catalysis. 2023; 6(10): 927-938. https://doi.org/10.1038/s41929-023-01018-y
    DORA PSI
  • Emmert S, Quargnali G, Thallmair S, Rivera-Fuentes P
    A locally activatable sensor for robust quantification of organellar glutathione
    Nature Chemistry. 2023; 15: 1415-1421. https://doi.org/10.1038/s41557-023-01249-3
    DORA PSI
  • Engrola F, Correia MAS, Watson C, Romão CC, Veiros LF, Romão MJ, et al.
    Arsenite oxidase in complex with antimonite and arsenite oxyanions: insights into the catalytic mechanism
    Journal of Biological Chemistry. 2023; 299(8): 105036 (9 pp.). https://doi.org/10.1016/j.jbc.2023.105036
    DORA PSI
  • Estévez-Gallego J, Álvarez-Bernad B, Pera B, Wullschleger C, Raes O, Menche D, et al.
    Chemical modulation of microtubule structure through the laulimalide/peloruside site
    Structure. 2023; 31(1): 88-99.e5. https://doi.org/10.1016/j.str.2022.11.006
    DORA PSI
  • Farnung J, Muhar M, Liang JR, Tolmachova KA, Benoit RM, Corn JE, et al.
    Semisynthetic LC3 probes for autophagy pathways reveal a noncanonical LC3 interacting region motif crucial for the enzymatic activity of human ATG3
    ACS Central Science. 2023; 9(5): 1025-1034. https://doi.org/10.1021/acscentsci.3c00009
    DORA PSI
  • Gkeka A, Aresta-Branco F, Triller G, Vlachou EP, van Straaten M, Lilic M, et al.
    Immunodominant surface epitopes power immune evasion in the African trypanosome
    Cell Reports. 2023; 42(3): 112262 (21 pp.). https://doi.org/10.1016/j.celrep.2023.112262
    DORA PSI
  • Glögl M, Friedrich N, Cerutti G, Lemmin T, Kwon YD, Gorman J, et al.
    Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization
    Nature Structural and Molecular Biology. 2023; 30: 1323-1336. https://doi.org/10.1038/s41594-023-01062-z
    DORA PSI
  • Greisen PJ, Yi L, Zhou R, Zhou J, Johansson E, Dong T, et al.
    Computational design of N‐linked glycans for high throughput epitope profiling
    Protein Science. 2023; 32(10): e4726 (11 pp.). https://doi.org/10.1002/pro.4726
    DORA PSI
  • Guo Y, Du X, Krusche J, Beck C, Ali S, Walter A, et al.
    Invasive Staphylococcus epidermidis uses a unique processive wall teichoic acid glycosyltransferase to evade immune recognition
    Science Advances. 2023; 9(47): eadj2641 (15 pp.). https://doi.org/10.1126/sciadv.adj2641
    DORA PSI
  • Guo Y, Alvigini L, Saifuddin M, Ashley B, Trajkovic M, Alonso-Cotchico L, et al.
    One-pot biocatalytic synthesis of rac-syringaresinol from a lignin-derived phenol
    ACS Catalysis. 2023; 13(22): 14639-14649. https://doi.org/10.1021/acscatal.3c04399
    DORA PSI
  • Hamed MM, Abdelsamie AS, Rox K, Schütz C, Kany AM, Röhrig T, et al.
    Towards translation of PqsR inverse agonists: from in vitro efficacy optimization to In vivo proof-of-principle
    Advanced Science. 2023; 10(5): 2204443 (14 pp.). https://doi.org/10.1002/advs.202204443
    DORA PSI
  • Hamid R, Adam S, Lacour A, Monjas L, Köhnke J, Hirsch AKH
    1-deoxy-D-xylulose-5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding
    Journal of Biological Chemistry. 2023; 299(9): 105152 (11 pp.). https://doi.org/10.1016/j.jbc.2023.105152
    DORA PSI
  • Hasyeoui M, Lassagne F, Erb W, Nael M, Elokely KM, Chaikuad A, et al.
    Oxazolo[5,4-f]quinoxaline-type selective inhibitors of glycogen synthase kinase-3α (GSK-3α): Development and impact on temozolomide treatment of glioblastoma cells
    Bioorganic Chemistry. 2023; 134: 106456 (18 pp.). https://doi.org/10.1016/j.bioorg.2023.106456
    DORA PSI
  • Igareta NV, Tachibana R, Spiess DC, Peterson RL, Ward TR
    Spiers memorial lecture: shielding the active site: a streptavidin superoxide-dismutase chimera as a host protein for asymmetric transfer hydrogenation
    Faraday Discussions. 2023; 244: 9-20. https://doi.org/10.1039/d3fd00034f
    DORA PSI
  • Isaikina P, Petrovic I, Jakob RP, Sarma P, Ranjan A, Baruah M, et al.
    A key GPCR phosphorylation motif discovered in arrestin2⋅CCR5 phosphopeptide complexes
    Molecular Cell. 2023; 83(12): 2108-2121.e7. https://doi.org/10.1016/j.molcel.2023.05.002
    DORA PSI
  • Jespersen M, Wagner T
    Assimilatory sulfate reduction in the marine methanogen Methanothermococcus thermolithotrophicus
    Nature Microbiology. 2023; 8(7): 1227-1239. https://doi.org/10.1038/s41564-023-01398-8
    DORA PSI
  • Jespersen M, Pierik AJ, Wagner T
    Structures of the sulfite detoxifying F420-dependent enzyme from Methanococcales
    Nature Chemical Biology. 2023; 19: 695-702. https://doi.org/10.1038/s41589-022-01232-y
    DORA PSI
  • Juroszek R, Galuskina I, Krüger B, Krüger H, Vapnik Y, Kahlenberg V, et al.
    Minerals with a palmierite-type structure. Part I. Mazorite Ba3(PO4)2, a new mineral from the Hatrurim Complex in Israel
    Mineralogical Magazine. 2023; 87(5): 679-689. https://doi.org/10.1180/mgm.2023.57
    DORA PSI
  • Kirchgäßner S, Braun MB, Bartlick N, Koç C, Reinkemeier CD, Lemke EA, et al.
    Synthesis, biochemical characterization, and genetic encoding of a 1,2,4-triazole amino acid as an acetyllysine mimic for bromodomains of the BET Family
    Angewandte Chemie International Edition. 2023; 62(12): e202215460 (7 pp.). https://doi.org/10.1002/anie.202215460
    DORA PSI
  • Krüger B, Galuskina IO, Galuskin EV, Vapnik Y, Murashko MN
    Khurayyimite Ca7Zn4(Si2O7)2(OH)10·4H2O: a mineral with unusual loop-branched sechser single chains
    Mineralogy and Petrology. 2023; 117(2): 191-200. https://doi.org/10.1007/s00710-022-00804-z
    DORA PSI
  • Lemaire ON, Belhamri M, Wagner T
    Structural and biochemical elucidation of class I hybrid cluster protein natively extracted from a marine methanogenic archaeon
    Frontiers in Microbiology. 2023; 14: 1179204 (16 pp.). https://doi.org/10.3389/fmicb.2023.1179204
    DORA PSI
  • Lenza MP, Egia-Mendikute L, Antoñana-Vildosola A, Soares CO, Coelho H, Corzana F, et al.
    Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b
    Nature Communications. 2023; 14(1): 3496 (14 pp.). https://doi.org/10.1038/s41467-023-39119-8
    DORA PSI
  • Lenza MP, Atxabal U, Nycholat C, Oyenarte I, Franconetti A, Quintana JI, et al.
    Structures of the inhibitory receptor siglec-8 in complex with a high-affinity sialoside analogue and a therapeutic antibody
    JACS Au. 2023; 3(1): 204-215. https://doi.org/10.1021/jacsau.2c00592
    DORA PSI
  • Maurer SK, Mayer MP, Ward SJ, Boudjema S, Halawa M, Zhang J, et al.
    Ubiquitin-specific protease 11 structure in complex with an engineered substrate mimetic reveals a molecular feature for deubiquitination selectivity
    Journal of Biological Chemistry. 2023; 299(11): 105300 (15 pp.). https://doi.org/10.1016/j.jbc.2023.105300
    DORA PSI
  • Nai F, Flores Espinoza MP, Invernizzi A, Vargas-Rosales PA, Bobileva O, Herok M, et al.
    Small-molecule inhibitors of the m7G-RNA writer METTL1
    ACS Bio & Med Chem Au. 2023. https://doi.org/10.1021/acsbiomedchemau.3c00030
    DORA PSI
  • Nemergut M, Marques SM, Uhrik L, Vanova T, Nezvedova M, Gadara DC, et al.
    Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer’s disease drug candidate
    Molecular Neurodegeneration. 2023; 18(1): 38 (25 pp.). https://doi.org/10.1186/s13024-023-00620-9
    DORA PSI
  • Nóbrega CS, Carvalho AL, Romão MJ, Pauleta SR
    Structural characterization of Neisseria gonorrhoeae bacterial peroxidase-insights into the catalytic cycle of bacterial peroxidases
    International Journal of Molecular Sciences. 2023; 24(7): 6246 (21 pp.). https://doi.org/10.3390/ijms24076246
    DORA PSI
  • Němec V, Khirsariya P, Janovská P, Moyano PM, Maier L, Procházková P, et al.
    Discovery of potent and exquisitely selective inhibitors of kinase CK1 with tunable isoform selectivity
    Angewandte Chemie International Edition. 2023; 62(11): e202217532 (7 pp.). https://doi.org/10.1002/anie.202217532
    DORA PSI
  • Personne H, Paschoud T, Fulgencio S, Baeriswyl S, Köhler T, van Delden C, et al.
    To fold or not to fold: diastereomeric optimization of an α-helical antimicrobial peptide
    Journal of Medicinal Chemistry. 2023; 66(11): 7570-7583. https://doi.org/10.1021/acs.jmedchem.3c00460
    DORA PSI
  • Prota AE, Lucena-Agell D, Ma Y, Estevez-Gallego J, Li S, Bargsten K, et al.
    Structural insight into the stabilization of microtubules by taxanes
    eLife. 2023; 12: e84791 (35 pp.). https://doi.org/10.7554/elife.84791
    DORA PSI
  • Qin B, Li Z, Tang K, Wang T, Xie Y, Aumonier S, et al.
    Identification of the SARS-unique domain of SARS-CoV-2 as an antiviral target
    Nature Communications. 2023; 14(1): 3999 (13 pp.). https://doi.org/10.1038/s41467-023-39709-6
    DORA PSI
  • Racle J, Guillaume P, Schmidt J, Michaux J, Larabi A, Lau K, et al.
    Machine learning predictions of MHC-II specificities reveal alternative binding mode of class II epitopes
    Immunity. 2023; 56(6): 1359-1375.e13. https://doi.org/10.1016/j.immuni.2023.03.009
    DORA PSI
  • Rahimova R, Nogaret P, Huteau V, Gelin M, Clément DA, Labesse G, et al.
    Structure-based design, synthesis and biological evaluation of a NAD+ analogue targeting Pseudomonas aeruginosa NAD kinase
    FEBS Journal. 2023; 290(2): 482-501. https://doi.org/10.1111/febs.16604
    DORA PSI
  • Rodriguez I, Kocik-Krol J, Skalniak L, Musielak B, Wisniewska A, Ciesiołkiewicz A, et al.
    Structural and biological characterization of pAC65, a macrocyclic peptide that blocks PD-L1 with equivalent potency to the FDA-approved antibodies
    Molecular Cancer. 2023; 22(1): 150 (8 pp.). https://doi.org/10.1186/s12943-023-01853-4
    DORA PSI
  • Sahoo PK, Sheenu, Jain D
    REC domain stabilizes the active heptamer of σ54-dependent transcription factor, FleR from Pseudomonas aeruginosa
    iScience. 2023; 26(12): 108397 (20 pp.). https://doi.org/10.1016/j.isci.2023.108397
    DORA PSI
  • Sahu S, Ekundayo BE, Kumar A, Bleichert F
    A dual role for the chromatin reader ORCA/LRWD1 in targeting the origin recognition complex to chromatin
    EMBO Journal. 2023; 42(18): e114654 (24 pp.). https://doi.org/10.15252/embj.2023114654
    DORA PSI
  • Salgado-Polo F, Borza R, Matsoukas M-T, Marsais F, Jagerschmidt C, Waeckel L, et al.
    Autotaxin facilitates selective LPA receptor signaling
    Cell Chemical Biology. 2023; 30(1): 69-84.e14. https://doi.org/10.1016/j.chembiol.2022.12.006
    DORA PSI
  • Schenkmayerova A, Toul M, Pluskal D, Baatallah R, Gagnot G, Pinto GP, et al.
    Catalytic mechanism for Renilla-type luciferases
    Nature Catalysis. 2023; 6(1): 23-38. https://doi.org/10.1038/s41929-022-00895-z
    DORA PSI
  • Schwalm MP, Krämer A, Dölle A, Weckesser J, Yu X, Jin J, et al.
    Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization
    Cell Chemical Biology. 2023; 30(7): 753-765.e8. https://doi.org/10.1016/j.chembiol.2023.06.002
    DORA PSI
  • Smith KML, Panepucci E, Kaminski JW, Aumonier S, Huang C-Y, Eris D, et al.
    SDU - software for high-throughput automated data collection at the Swiss Light Source
    Journal of Synchrotron Radiation. 2023; 30: 538-545. https://doi.org/10.1107/S1600577523002631
    DORA PSI
  • Snajdarova K, Marques SM, Damborsky J, Bednar D, Marek M
    Atypical homodimerization revealed by the structure of the (S)-enantioselective haloalkane dehalogenase DmmarA from Mycobacterium marinum
    Acta Crystallographica Section D: Structural Biology. 2023; 79(Pt 11): 956-970. https://doi.org/10.1107/S2059798323006642
    DORA PSI
  • Sorin MN, Di Maio A, Silva LM, Ebert D, Delannoy CP, Nguyen N-K, et al.
    Structural and functional analysis of natural capsid variants suggests sialic acid-independent entry of BK polyomavirus
    Cell Reports. 2023; 42(2): 112114 (18 pp.). https://doi.org/10.1016/j.celrep.2023.112114
    DORA PSI
  • Stasiak AC, Gogler K, Borisova M, Fink P, Mayer C, Stehle T, et al.
    N-acetylmuramic acid recognition by MurK kinase from the MurNAc auxotrophic oral pathogen Tannerella forsythia
    Journal of Biological Chemistry. 2023; 299(9): 105076 (13 pp.). https://doi.org/10.1016/j.jbc.2023.105076
    DORA PSI
  • Stegmann DP, Steuber J, Fritz G, Wojdyla JA, Sharpe ME
    Fast fragment and compound screening pipeline at the Swiss Light Source
    In: Methods in enzymology. sine loco: Elsevier; 2023:235-284. https://doi.org/10.1016/bs.mie.2023.08.005
    DORA PSI
  • Takase S, Hiroyama T, Shirai F, Maemoto Y, Nakata A, Arata M, et al.
    A specific G9a inhibitor unveils BGLT3 lncRNA as a universal mediator of chemically induced fetal globin gene expression
    Nature Communications. 2023; 14(1): 23 (18 pp.). https://doi.org/10.1038/s41467-022-35404-0
    DORA PSI
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