X06DA PDB Structure Gallery from BioSync
PXIII Publications
Recent publications are listed below. For an extensive overview we kindly refer you to our publication repository DORA
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Atkinson SJ, Bagal SK, Argyrou A, Askin S, Cheung T, Chiarparin E, et al.
Development of a series of pyrrolopyridone MAT2A inhibitors
Journal of Medicinal Chemistry. 2024; 67(6): 4541-4559. https://doi.org/10.1021/acs.jmedchem.3c01860
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Batchelor LK, De Falco L, Dyson PJ, Davey CA
Viral peptide conjugates for metal-warhead delivery to chromatin
RSC Advances. 2024; 14(13): 8718-8725. https://doi.org/10.1039/d4ra01617c
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Bauer N, Balourdas DI, Schneider JR, Zhang X, Berger LM, Berger BT, et al.
Development of potent dual BET/HDAC inhibitors via pharmacophore merging and structure-guided optimization
ACS Chemical Biology. 2024; 19(2): 266-279. https://doi.org/10.1021/acschembio.3c00427
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Compain G, Monsarrat C, Blagojevic J, Brillet K, Dumas P, Hammann P, et al.
Peptide-based covalent inhibitors bearing mild electrophiles to target a conserved his residue of the bacterial sliding clamp
JACS Au. 2024; 4(2): 432-440. https://doi.org/10.1021/jacsau.3c00572
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Corbeski I, Vargas-Rosales PA, Bedi RK, Deng J, Coelho D, Braud E, et al.
The catalytic mechanism of the RNA methyltransferase METTL3
eLife. 2024; 12: RP92537 (27 pp.). https://doi.org/10.7554/eLife.92537
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D'Agostino M, Simonetti A, Motta S, Wolff P, Romagnoli A, Piccinini A, et al.
Crystal structure of archaeal IF5A-DHS complex reveals insights into the hypusination mechanism
Structure. 2024; 32(7): 878-888.e4. https://doi.org/10.1016/j.str.2024.03.008
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Fu C, Liu Y, Walt C, Rasheed S, Bader CD, Lukat P, et al.
Elucidation of unusual biosynthesis and DnaN-targeting mode of action of potent anti-tuberculosis antibiotics Mycoplanecins
Nature Communications. 2024; 15(1): 791 (13 pp.). https://doi.org/10.1038/s41467-024-44953-5
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Galuskin EV, Krüger B, Galuskina IO, Krüger H, Nejbert K, Vapnik Y
Gorerite, CaAlFe11O19, a new mineral of the magnetoplumbite group from the Negev Desert, Israel
Mineralogical Magazine. 2024. https://doi.org/10.1180/mgm.2024.30
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Greco FA, Krämer A, Wahl L, Elson L, Ehret TAL, Gerninghaus J, et al.
Synthesis and evaluation of chemical linchpins for highly selective CK2α targeting
European Journal of Medicinal Chemistry. 2024; 276: 116672 (22 pp.). https://doi.org/10.1016/j.ejmech.2024.116672
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Hazemann J, Kimmerlin T, Lange R, Sweeney AM, Bourquin G, Ritz D, et al.
Identification of SARS-CoV-2 Mpro inhibitors through deep reinforcement learning for de novo drug design and computational chemistry approaches
RSC Medicinal Chemistry. 2024; 15(6): 2146-2159. https://doi.org/10.1039/d4md00106k
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Heine N, Weber A, Pautsch A, Gottschling D, Uphues I, Bauer M, et al.
Discovery of BI-9787, a potent zwitterionic ketohexokinase inhibitor with oral bioavailability
Bioorganic and Medicinal Chemistry Letters. 2024; 112: 129930 (9 pp.). https://doi.org/10.1016/j.bmcl.2024.129930
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Hiller M, Diwo M, Wamp S, Gutsmann T, Lang C, Blankenfeldt W, et al.
Structure–function relationships underpin disulfide loop cleavage-dependent activation of Legionella pneumophila lysophospholipase A PlaA
Molecular Microbiology. 2024; 121(3): 497-512. https://doi.org/10.1111/mmi.15201
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Jungfer K, Sigg A, Jinek M
Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2
Nucleic Acids Research. 2024; 52(1): 462-473. https://doi.org/10.1093/nar/gkad1102
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Kjeldsen T, Andersen AS, Hubálek F, Johansson E, Kreiner FF, Schluckebier G, et al.
Molecular engineering of insulin for recombinant expression in yeast
Trends in Biotechnology. 2024; 42(4): 464-478. https://doi.org/10.1016/j.tibtech.2023.09.012
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Kuhn BT, Zöller J, Zimmermann I, Gemeinhardt T, Özkul DH, Langer JD, et al.
Interdomain-linkers control conformational transitions in the SLC23 elevator transporter UraA
Nature Communications. 2024; 15(1): 7518 (12 pp.). https://doi.org/10.1038/s41467-024-51814-8
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Maslać N, Cadoux C, Bolte P, Murken F, Gu W, Milton RD, et al.
Structural comparison of (hyper-)thermophilic nitrogenase reductases from three marine Methanococcales
FEBS Journal. 2024; 291(15): 3454-3480. https://doi.org/10.1111/febs.17148
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Mastria R, Riisnaes KJ, Bacon A, Leontis I, Lam HT, Alshehri MAS, et al.
Real time and highly sensitive sub-wavelength 2D hybrid perovskite photodetectors
Advanced Functional Materials. 2024. https://doi.org/10.1002/adfm.202401903
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Meinhold S, Zdanowicz R, Giese C, Glockshuber R
Dimerization of a 5-kDa domain defines the architecture of the 5-MDa gammaproteobacterial pyruvate dehydrogenase complex
Science Advances. 2024; 10(6): eadj6358 (17 pp.). https://doi.org/10.1126/sciadv.adj6358
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Montserrat-Gomez M, Gogl G, Carrasco K, Betzi S, Durbesson F, Cousido-Siah A, et al.
PDZome-wide and structural characterization of the PDZ-binding motif of VANGL2
Biochimica et Biophysica Acta: Proteins and Proteomics. 2024; 1872(3): 140989 (17 pp.). https://doi.org/10.1016/j.bbapap.2023.140989
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Mukherjee M, Day PJ, Laverty D, Bueren-Calabuig JA, Woodhead AJ, Griffiths-Jones C, et al.
Protein engineering enables a soakable crystal form of human CDK7 primed for high-throughput crystallography and structure-based drug design
Structure. 2024; 32(8): 1040-1048.e3. https://doi.org/10.1016/j.str.2024.05.011
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Müller MC, Lemaire ON, Kurth JM, Welte CU, Wagner T
Differences in regulation mechanisms of glutamine synthetases from methanogenic archaea unveiled by structural investigations
Communications Biology. 2024; 7(1): 111. https://doi.org/10.1038/s42003-023-05726-w
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Münzker L, Kimani SW, Fowkes MM, Dong A, Zheng H, Li Y, et al.
A ligand discovery toolbox for the WWE domain family of human E3 ligases
Communications Biology. 2024; 7(1): 901 (15 pp.). https://doi.org/10.1038/s42003-024-06584-w
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Nalivaiko EY, Vasseur CM, Seebeck FP
Enzyme-catalyzed oxidative degradation of ergothioneine
Angewandte Chemie International Edition. 2024; 63(8): e202318445 (8 pp.). https://doi.org/10.1002/anie.202318445
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Ober VT, Githure GB, Volpato Santos Y, Becker S, Moya Munoz G, Basquin J, et al.
Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens
eLife. 2024; 12: RP91040 (33 pp.). https://doi.org/10.7554/eLife.91040
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Obergfell E, Hohmann U, Moretti A, Chen H, Hothorn M
Mechanistic insights into the function of 14-3-3 proteins as negative regulators of Brassinosteroid signaling in Arabidopsis
Plant and Cell Physiology. 2024. https://doi.org/10.1093/pcp/pcae056
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Palmer N, Agnew C, Benn C, Buffham WJ, Castro JN, Chessari G, et al.
Fragment-based discovery of a series of allosteric-binding site modulators of β-glucocerebrosidase
Journal of Medicinal Chemistry. 2024; 67(13): 11168-11181. https://doi.org/10.1021/acs.jmedchem.4c00702
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Proske M, Janowski R, Bacher S, Kang HS, Monecke T, Koehler T, et al.
PURA syndrome-causing mutations impair PUR-domain integrity and affect P-body association
eLife. 2024; 13: RP93561 (27 pp.). https://doi.org/10.7554/eLife.93561
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Rak M, Menge A, Tesch R, Berger LM, Balourdas DI, Shevchenko E, et al.
Development of selective pyrido[2,3-d]pyrimidin-7(8H)-one-based Mammalian STE20-like (MST3/4) kinase inhibitors
Journal of Medicinal Chemistry. 2024; 67(5): 3813-3842. https://doi.org/10.1021/acs.jmedchem.3c02217
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Vitoria Gomes M, Landwerlin P, Diebold-Durand M-L, Shaik TB, Durand A, Troesch E, et al.
The cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains
Cell Reports. 2024; 43(9): 114656 (24 pp.). https://doi.org/10.1016/j.celrep.2024.114656
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Wohlwend D, Mérono L, Bucka S, Ritter K, Jessen HJ, Friedrich T
Structures of 3-acetylpyridine adenine dinucleotide and ADP-ribose bound to the electron input module of respiratory complex I
Structure. 2024; 32(6): 715-724.e3. https://doi.org/10.1016/j.str.2024.02.013
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Zálešák F, Nai F, Herok M, Bochenkova E, Bedi RK, Li Y, et al.
Structure-based design of a potent and selective YTHDC1 ligand
Journal of Medicinal Chemistry. 2024; 67: 9516-9535. https://doi.org/10.1021/acs.jmedchem.4c00599
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Adam S, Zheng D, Klein A, Volz C, Mullen W, Shirran SL, et al.
Unusual peptide-binding proteins guide pyrroloindoline alkaloid formation in crocagin biosynthesis
Nature Chemistry. 2023; 15(4): 560-568. https://doi.org/10.1038/s41557-023-01153-w
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Alvarez HA, Cousido-Siah A, Espinosa YR, Podjarny A, Carlevaro CM, Howard E
Lipid exchange in crystal-confined fatty acid binding proteins: X-ray evidence and molecular dynamics explanation
Proteins. 2023; 91(11): 1525-1534. https://doi.org/10.1002/prot.26546
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Anso I, Naegeli A, Cifuente JO, Orrantia A, Andersson E, Zenarruzabeitia O, et al.
Turning universal O into rare Bombay type blood
Nature Communications. 2023; 14(1): 1765 (16 pp.). https://doi.org/10.1038/s41467-023-37324-z
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Arifi S, Marschner JA, Pollinger J, Isigkeit L, Heitel P, Kaiser A, et al.
Targeting the alternative vitamin E metabolite binding site enables noncanonical PPARγ modulation
Journal of the American Chemical Society. 2023; 145(27): 14802-14810. https://doi.org/10.1021/jacs.3c03417
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Bashore FM, Marquez AB, Chaikuad A, Howell S, Dunn AS, Beltran AA, et al.
Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis
Scientific Reports. 2023; 13(1): 6118 (17 pp.). https://doi.org/10.1038/s41598-023-32854-4
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Bedi RK, Huang D, Li Y, Caflisch A
Structure-based design of inhibitors of the m6A-RNA writer enzyme METTL3
ACS Bio & Med Chem Au. 2023; 3(4): 359-370. https://doi.org/10.1021/acsbiomedchemau.3c00023
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Billiald P, Slater A, Welin M, Clark JC, Loyau S, Pugnière M, et al.
Targeting platelet GPVI with glenzocimab: a novel mechanism for inhibition
Blood Advances. 2023; 7(7): 1258-1268. https://doi.org/10.1182/bloodadvances.2022007863
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Boiarska Z, Pérez-Peña H, Abel A-C, Marzullo P, Álvarez-Bernad B, Bonato F, et al.
Maytansinol functionalization: towards useful probes for studying microtubule dynamics
Chemistry: A European Journal. 2023; 29(5): e202203431 (12 pp.). https://doi.org/10.1002/chem.202203431
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Brkic A, Leibundgut M, Jablonska J, Zanki V, Car Z, Petrovic Perokovic V, et al.
Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif
Nature Communications. 2023; 14(1): 5498 (12 pp.). https://doi.org/10.1038/s41467-023-41244-3
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Bui TYH, De Zitter E, Moeyaert B, Pecqueur L, Srinivasu BY, Economou A, et al.
Oxygen-induced chromophore degradation in the photoswitchable red fluorescent protein rsCherry
International Journal of Biological Macromolecules. 2023; 239: 124179 (9 pp.). https://doi.org/10.1016/j.ijbiomac.2023.124179
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Busch MR, Rajendran C, Sterner R
Structural and functional characterization of the ureidoacrylate amidohydrolase RutB from Escherichia coli
Biochemistry. 2023; 62(3): 863-872. https://doi.org/10.1021/acs.biochem.2c00640
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Cadoux C, Ratcliff D, Maslać N, Gu W, Tsakoumagkos I, Hoogendoorn S, et al.
Nitrogen fixation and hydrogen evolution by sterically encumbered Mo-nitrogenase
JACS Au. 2023; 3(5): 1521-1533. https://doi.org/10.1021/jacsau.3c00165
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Cadoux C, Maslać N, Di Luzio L, Ratcliff D, Gu W, Wagner T, et al.
The mononuclear metal-binding site of Mo-nitrogenase is not required for activity
JACS Au. 2023; 3(11): 2993-2999. https://doi.org/10.1021/jacsau.3c00567
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Chandra M, Đaković S, Foti K, Zeelen JP, van Straaten M, Aresta-Branco F, et al.
Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome
PLoS Neglected Tropical Diseases. 2023; 17(2): e0011093 (18 pp.). https://doi.org/10.1371/journal.pntd.0011093
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Chmelova K, Gao T, Polak M, Schenkmayerova A, Croll TI, Shaikh TR, et al.
Multimeric structure of a subfamily III haloalkane dehalogenase‐like enzyme solved by combination of cryo‐EM and x‐ray crystallography
Protein Science. 2023; 32(10): e4751 (22 pp.). https://doi.org/10.1002/pro.4751
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De Simone M, Alvigini L, Alonso-Cotchico L, Brissos V, Caroli J, Lucas MF, et al.
Rationally guided improvement of NOV1 dioxygenase for the conversion of lignin-derived isoeugenol to vanillin
Biochemistry. 2023; 62(2): 419-428. https://doi.org/10.1021/acs.biochem.2c00168
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Denkhaus L, Siffert F, Einsle O
An unusual active site architecture in cytochrome c nitrite reductase NrfA-1 from Geobacter metallireducens
FEMS Microbiology Letters. 2023; 370: 1-8. https://doi.org/10.1093/femsle/fnad068
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Dubey BN, Shyp V, Fucile G, Sondermann H, Jenal U, Schirmer T
Mutant structure of metabolic switch protein in complex with monomeric c-di-GMP reveals a potential mechanism of protein-mediated ligand dimerization
Scientific Reports. 2023; 13(1): 2727 (13 pp.). https://doi.org/10.1038/s41598-023-29110-0
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Díaz-Perlas C, Ricken B, Farrera-Soler L, Guschin D, Pojer F, Lau K, et al.
High-affinity peptides developed against calprotectin and their application as synthetic ligands in diagnostic assays
Nature Communications. 2023; 14(1): 2774 (14 pp.). https://doi.org/10.1038/s41467-023-38075-7
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Dürvanger Z, Juhász T, Liliom K, Harmat V
Structures of calmodulin–melittin complexes show multiple binding modes lacking classical anchoring interactions
Journal of Biological Chemistry. 2023; 299(4): 104596 (15 pp.). https://doi.org/10.1016/j.jbc.2023.104596
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Ebenhoch R, Bauer M, Romig H, Gottschling D, Kley JT, Heine N, et al.
Crystal structures of human and mouse ketohexokinase provide a structural basis for species- and isoform-selective inhibitor design
Acta Crystallographica Section D: Structural Biology. 2023; 79(10): 871-880. https://doi.org/10.1107/S2059798323006137
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Eichenberger M, Schwander T, Hüppi S, Kreuzer J, Mittl PRE, Peccati F, et al.
The catalytic role of glutathione transferases in heterologous anthocyanin biosynthesis
Nature Catalysis. 2023; 6(10): 927-938. https://doi.org/10.1038/s41929-023-01018-y
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Emmert S, Quargnali G, Thallmair S, Rivera-Fuentes P
A locally activatable sensor for robust quantification of organellar glutathione
Nature Chemistry. 2023; 15: 1415-1421. https://doi.org/10.1038/s41557-023-01249-3
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Engrola F, Correia MAS, Watson C, Romão CC, Veiros LF, Romão MJ, et al.
Arsenite oxidase in complex with antimonite and arsenite oxyanions: insights into the catalytic mechanism
Journal of Biological Chemistry. 2023; 299(8): 105036 (9 pp.). https://doi.org/10.1016/j.jbc.2023.105036
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Estiri H, Bhattacharya S, Buitrago JAR, Castagna R, Legzdiņa L, Casucci G, et al.
Tailoring FPOX enzymes for enhanced stability and expanded substrate recognition
Scientific Reports. 2023; 13(1): 18610 (12 pp.). https://doi.org/10.1038/s41598-023-45428-1
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Estévez-Gallego J, Álvarez-Bernad B, Pera B, Wullschleger C, Raes O, Menche D, et al.
Chemical modulation of microtubule structure through the laulimalide/peloruside site
Structure. 2023; 31(1): 88-99.e5. https://doi.org/10.1016/j.str.2022.11.006
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Farnung J, Muhar M, Liang JR, Tolmachova KA, Benoit RM, Corn JE, et al.
Semisynthetic LC3 probes for autophagy pathways reveal a noncanonical LC3 interacting region motif crucial for the enzymatic activity of human ATG3
ACS Central Science. 2023; 9(5): 1025-1034. https://doi.org/10.1021/acscentsci.3c00009
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Gkeka A, Aresta-Branco F, Triller G, Vlachou EP, van Straaten M, Lilic M, et al.
Immunodominant surface epitopes power immune evasion in the African trypanosome
Cell Reports. 2023; 42(3): 112262 (21 pp.). https://doi.org/10.1016/j.celrep.2023.112262
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Glögl M, Friedrich N, Cerutti G, Lemmin T, Kwon YD, Gorman J, et al.
Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization
Nature Structural and Molecular Biology. 2023; 30: 1323-1336. https://doi.org/10.1038/s41594-023-01062-z
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Greisen PJ, Yi L, Zhou R, Zhou J, Johansson E, Dong T, et al.
Computational design of N‐linked glycans for high throughput epitope profiling
Protein Science. 2023; 32(10): e4726 (11 pp.). https://doi.org/10.1002/pro.4726
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Guo Y, Du X, Krusche J, Beck C, Ali S, Walter A, et al.
Invasive Staphylococcus epidermidis uses a unique processive wall teichoic acid glycosyltransferase to evade immune recognition
Science Advances. 2023; 9(47): eadj2641 (15 pp.). https://doi.org/10.1126/sciadv.adj2641
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Guo Y, Alvigini L, Saifuddin M, Ashley B, Trajkovic M, Alonso-Cotchico L, et al.
One-pot biocatalytic synthesis of rac-syringaresinol from a lignin-derived phenol
ACS Catalysis. 2023; 13(22): 14639-14649. https://doi.org/10.1021/acscatal.3c04399
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Hamed MM, Abdelsamie AS, Rox K, Schütz C, Kany AM, Röhrig T, et al.
Towards translation of PqsR inverse agonists: from in vitro efficacy optimization to In vivo proof-of-principle
Advanced Science. 2023; 10(5): 2204443 (14 pp.). https://doi.org/10.1002/advs.202204443
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Hamid R, Adam S, Lacour A, Monjas L, Köhnke J, Hirsch AKH
1-deoxy-D-xylulose-5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding
Journal of Biological Chemistry. 2023; 299(9): 105152 (11 pp.). https://doi.org/10.1016/j.jbc.2023.105152
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Hasyeoui M, Lassagne F, Erb W, Nael M, Elokely KM, Chaikuad A, et al.
Oxazolo[5,4-f]quinoxaline-type selective inhibitors of glycogen synthase kinase-3α (GSK-3α): Development and impact on temozolomide treatment of glioblastoma cells
Bioorganic Chemistry. 2023; 134: 106456 (18 pp.). https://doi.org/10.1016/j.bioorg.2023.106456
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Igareta NV, Tachibana R, Spiess DC, Peterson RL, Ward TR
Spiers memorial lecture: shielding the active site: a streptavidin superoxide-dismutase chimera as a host protein for asymmetric transfer hydrogenation
Faraday Discussions. 2023; 244: 9-20. https://doi.org/10.1039/d3fd00034f
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Isaikina P, Petrovic I, Jakob RP, Sarma P, Ranjan A, Baruah M, et al.
A key GPCR phosphorylation motif discovered in arrestin2⋅CCR5 phosphopeptide complexes
Molecular Cell. 2023; 83(12): 2108-2121.e7. https://doi.org/10.1016/j.molcel.2023.05.002
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Jespersen M, Wagner T
Assimilatory sulfate reduction in the marine methanogen Methanothermococcus thermolithotrophicus
Nature Microbiology. 2023; 8(7): 1227-1239. https://doi.org/10.1038/s41564-023-01398-8
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Jespersen M, Pierik AJ, Wagner T
Structures of the sulfite detoxifying F420-dependent enzyme from Methanococcales
Nature Chemical Biology. 2023; 19: 695-702. https://doi.org/10.1038/s41589-022-01232-y
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Juroszek R, Galuskina I, Krüger B, Krüger H, Vapnik Y, Kahlenberg V, et al.
Minerals with a palmierite-type structure. Part I. Mazorite Ba3(PO4)2, a new mineral from the Hatrurim Complex in Israel
Mineralogical Magazine. 2023; 87(5): 679-689. https://doi.org/10.1180/mgm.2023.57
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Kirchgäßner S, Braun MB, Bartlick N, Koç C, Reinkemeier CD, Lemke EA, et al.
Synthesis, biochemical characterization, and genetic encoding of a 1,2,4-triazole amino acid as an acetyllysine mimic for bromodomains of the BET Family
Angewandte Chemie International Edition. 2023; 62(12): e202215460 (7 pp.). https://doi.org/10.1002/anie.202215460
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Krüger B, Galuskina IO, Galuskin EV, Vapnik Y, Murashko MN
Khurayyimite Ca7Zn4(Si2O7)2(OH)10·4H2O: a mineral with unusual loop-branched sechser single chains
Mineralogy and Petrology. 2023; 117(2): 191-200. https://doi.org/10.1007/s00710-022-00804-z
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Lemaire ON, Belhamri M, Wagner T
Structural and biochemical elucidation of class I hybrid cluster protein natively extracted from a marine methanogenic archaeon
Frontiers in Microbiology. 2023; 14: 1179204 (16 pp.). https://doi.org/10.3389/fmicb.2023.1179204
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Lenza MP, Egia-Mendikute L, Antoñana-Vildosola A, Soares CO, Coelho H, Corzana F, et al.
Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b
Nature Communications. 2023; 14(1): 3496 (14 pp.). https://doi.org/10.1038/s41467-023-39119-8
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Lenza MP, Atxabal U, Nycholat C, Oyenarte I, Franconetti A, Quintana JI, et al.
Structures of the inhibitory receptor siglec-8 in complex with a high-affinity sialoside analogue and a therapeutic antibody
JACS Au. 2023; 3(1): 204-215. https://doi.org/10.1021/jacsau.2c00592
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Maurer SK, Mayer MP, Ward SJ, Boudjema S, Halawa M, Zhang J, et al.
Ubiquitin-specific protease 11 structure in complex with an engineered substrate mimetic reveals a molecular feature for deubiquitination selectivity
Journal of Biological Chemistry. 2023; 299(11): 105300 (15 pp.). https://doi.org/10.1016/j.jbc.2023.105300
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Nai F, Flores Espinoza MP, Invernizzi A, Vargas-Rosales PA, Bobileva O, Herok M, et al.
Small-molecule inhibitors of the m7G-RNA writer METTL1
ACS Bio & Med Chem Au. 2023; 4(2): 100-110. https://doi.org/10.1021/acsbiomedchemau.3c00030
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Nemergut M, Marques SM, Uhrik L, Vanova T, Nezvedova M, Gadara DC, et al.
Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer’s disease drug candidate
Molecular Neurodegeneration. 2023; 18(1): 38 (25 pp.). https://doi.org/10.1186/s13024-023-00620-9
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Nóbrega CS, Carvalho AL, Romão MJ, Pauleta SR
Structural characterization of Neisseria gonorrhoeae bacterial peroxidase-insights into the catalytic cycle of bacterial peroxidases
International Journal of Molecular Sciences. 2023; 24(7): 6246 (21 pp.). https://doi.org/10.3390/ijms24076246
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Němec V, Khirsariya P, Janovská P, Moyano PM, Maier L, Procházková P, et al.
Discovery of potent and exquisitely selective inhibitors of kinase CK1 with tunable isoform selectivity
Angewandte Chemie International Edition. 2023; 62(11): e202217532 (7 pp.). https://doi.org/10.1002/anie.202217532
DORA PSI -
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