Division of Biology and Chemistry (BIO)
News and Highlights
PSI is engaging in public outreach at a major event in Zürich, the "Scientifica" Science Days September 4 and 5.
Single-particle cryo-electron microscopy of a functional Aβ42 pore equivalent, created by fusing Aβ42 to the oligomerizing, soluble domain of the α-hemolysin toxin, offers new insights into structure and function of proteins forming amyloid aggregates in Alzheimer’s disease.
Using a combination of computer simulations and laboratory experiments, PSI researchers have identified new binding sites for active agents on the vital protein tubulin.
Imaging and sequencing techniques combined with machine learning offer researchers countless opportunities to look inside cells with greater precision than ever before. G.V. Shivashankar, lab head at PSI, describes how such information can be used to find answers to pressing questions.