Cartoon depicting FR as a molecular glue for Gα and Gβγ
Illustration created using Glibatree Art Designer, a custom GPT powered by OpenAI's DALL·E, and refined using ChatGPT with DALL·E image generation.
20.05.2025
•Health Innovation

From coral berries to new therapies: uncovering the molecular glue mechanism of natural compounds

Researchers at the Center for Life Sciences and the Center for Scientific Computing, Theory, and Data at the Paul Scherrer Institute have identified the mechanism by which certain natural compounds interfere with cellular signaling. These ‘molecular glues’ have a therapeutic potential for the treatment of specific cancer types. Their latest study on this topic has been published in the journal Proceedings of the National Academy of Sciences of the United States of America.

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Chromatin
12.05.2025
•Health Innovation
•8 min

Using AI to identify genetic perturbations from cell images

New AI identifies genetic perturbations in chromatin – a potential approach in diagnostics and drug development.

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Araris Team
17.03.2025
•Health Innovation
•5 min

A superlative milestone

PSI spin-off Araris Biotech AG achieves valuation at unicorn-level!

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Volodymyr M. Korkhov (left) and Richard Kammerer of the Center for Life Sciences at PSI have made important advances towards understanding how botulinum neurotoxin, botox for short, enters our nerve cells.
Volodymyr M. Korkhov (left) and Richard Kammerer of the Center for Life Sciences at PSI have made important advances towards understanding how botulinum neurotoxin, botox for short, enters our nerve cells. © Paul Scherrer Institute PSI/Mahir Dzambegovic
11.02.2025
•Health Innovation
•6 min

How botox enters our cells

Researchers at PSI have identified structural changes of the bacterial neurotoxin botox that are important for its uptake into nerve cells. This finding could allow a more targeted use of botox in medicine.

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PSI Center for Life Sciences

Tracing the secrets of life: The PSI Center for Life Sciences is pursuing research in the areas of structural biology, bioimaging and radiopharmacy.

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