Scientific Highlights

Datum
28. September 2021
Roger Benoit

Protein distancing

Media Releases Biology Human Health

PSI researchers have developed a new method to attach proteins to the surface of virus-like particles.

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7. Juni 2021
cryo-EM

Catching Alzheimer's Toxin

Single-particle cryo-electron microscopy of  a functional Aβ42 pore equivalent, created by fusing Aβ42 to the oligomerizing, soluble domain of the α-hemolysin  toxin, offers new insights into structure and function of proteins forming amyloid aggregates in Alzheimer’s disease.

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6. Mai 2021
Teaser Tubulin

Cell cytoskeleton as target for new active agents

Media Releases Research Using Synchrotron Light Biology Human Health

Using a combination of computer simulations and laboratory experiments, PSI researchers have identified new binding sites for active agents on the vital protein tubulin.

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4. Februar 2021
teaser

"Ultimately, we aim to understand how diseases start in single cells"

Biology Human Health Medical Science Proton Therapy

Imaging and sequencing techniques combined with machine learning offer researchers countless opportunities to look inside cells with greater precision than ever before. G.V. Shivashankar, lab head at PSI, describes how such information can be used to find answers to pressing questions.

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5. November 2020
Teaser ERC Grant

A new generation of optogenetic tools for research and medicine

Media Releases Biology

The European Research Council (ERC) is funding an interdisciplinary collaborative project with 10 million euros for the structural and biophysical analysis of selected photoreceptors and their development into "OptoGPCRs", light-controlled molecular switches with a wide range of applications in biology and medicine.

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