Publications

2022

2021

2020

2019

2018

  • CLASP Suppresses Microtubule Catastrophes through a Single TOG Domain. Aher A, Kok M, Sharma A, Rai A, Olieric N, Rodriguez-Garcia R, Katrukha EA, Weinert T, Olieric V, Kapitein LC, Steinmetz MO, Dogterom M, Akhmanova A
    DEVELOPMENTAL CELL 46, 40 (2018).
  • Cep120 promotes microtubule formation through a unique tubulin binding C2 domain Sharma A, Gerard Samuel F, Olieric N, Steinmetz Michel O
    JOURNAL OF STRUCTURAL BIOLOGY -, S1047847718300248 (2018).
    DOI: 10.1016/j.jsb.2018.01.009
  • Combinatorial use of disulfide bridges and native sulfur-SAD phasing for rapid structure determination of coiled-coils Kraatz Sebastian HW, Bianchi S, Steinmetz Michel O
    BIOSCIENCE REPORTS 38, BSR20181073 (2018).
    DOI: 10.1042/BSR20181073
  • Crystal structure of rhodopsin in complex with a mini-G o sheds light on the principles of G protein selectivity Tsai C, Pamula F, Nehmé R, Mühle J, Weinert T, Flock T, Nogly P, Edwards Patricia C, Carpenter B, Gruhl T, Ma P, Deupi X, Standfuss J, Tate Christopher G, Schertler Gebhard FX
    Science Advances 4, eaat7052 (2018).
    DOI: 10.1126/sciadv.aat7052
  • Development of Smart Optical Gels with Highly Magnetically Responsive Bicelles Isabettini S, Stucki S, Massabni S, Baumgartner ME, Reckey PQ, Kohlbrecher J, Ishikawa T, Windhab Erich J, Fischer P, Kuster S
    ACS APPLIED MATERIALS & INTERFACES 10, 8926 (2018).
    DOI: 10.1021/acsami.7b17134
  • Electron crystallography with the EIGER detector Tinti G, Fröjdh E, van Genderen E, Gruene T, Schmitt B, de Winter MDA, Weckhuysen BM, Abrahams J
    IUCRJ 5, 190 (2018).
    DOI: 10.1107/S2052252518000945
  • Expression and purification of the mammalian translocator protein for structural studies Graeber E, Korkhov Volodymyr M
    PLOS ONE 13, e0198832 (2018).
    DOI: 10.1371/journal.pone.0198832
  • Frontispiece: Characterization at the Level of Individual Crystals: Single-Crystal MFI Type Zeolite Grains Gruene T, Li T, van Genderen E, Pinar Ana B, van Bokhoven JA
    CHEMISTRY - A EUROPEAN JOURNAL 24, 2384 (2018).
    DOI: 10.1002/chem.201881065
  • In situ serial crystallography for rapid de novo membrane protein structure determination. Huang CY, Olieric V, Howe N, Warshamanage R, Weinert T, Panepucci E, Vogeley L, Basu S, Diederichs K, Caffrey M, Wang M
    Communications Biology 1, 124 (2018).
    DOI: 10.1038/S42003-018-0123-6
  • Ligand channel in pharmacologically stabilized rhodopsin. Mattle D, Kuhn B, Aebi J, Bedoucha M, Kekilli D, Grozinger N, Alker A, Rudolph MG, Schmid G, Schertler GFX, Hennig M, Standfuss J, Dawson RJP
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 115, 3640 (2018).
  • Microtubule-Targeting Agents: Strategies To Hijack the Cytoskeleton Steinmetz Michel O, Prota Andrea E
    TRENDS IN CELL BIOLOGY 28, 776 (2018).
    DOI: 10.1016/j.tcb.2018.05.001
  • Quinazolinone-Based Anticancer Agents: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Tubulin Co-crystal Structure Dohle W, Jourdan Fabrice L, Menchon G, Prota Andrea E, Foster Paul A, Mannion P, Hamel E, Thomas Mark P, Kasprzyk Philip G, Ferrandis E, Steinmetz Michel O, Leese Mathew P, Potter Barry VL
    JOURNAL OF MEDICINAL CHEMISTRY , acs.jmedchem.7b01474 (2018).
    DOI: 10.1021/acs.jmedchem.7b01474
  • Resolution extension by image summing in serial femtosecond crystallography of two-dimensional membrane-protein crystals Casadei Cecilia M, Tsai C, Barty A, Hunter Mark S, Zatsepin Nadia A, Padeste C, Capitani G, Benner WHenry, Boutet S, Hau-Riege Stefan P, Kupitz C, Messerschmidt M, Ogren John I, Pardini T, Rothschild Kenneth J, Sala L, Segelke B, Williams Garth J, Evans James E, Li X, Coleman M, Pedrini B, Frank M
    IUCRJ 5, 103 (2018).
    DOI: 10.1107/S2052252517017043
  • Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser Nogly P, Weinert T, James D, Carbajo S, Ozerov D, Furrer A, Gashi D, Borin V, Skopintsev P, Jaeger K, Nass K, Båth P, Bosman R, Koglin J, Seaberg M, Lane T, Kekilli D, Brünle S, Tanaka T, Wu W, Milne C, White T, Barty A, Weierstall U, Panneels V, Nango E, Iwata S, Hunter M, Schapiro I, Schertler G, Neutze R, Standfuss J
    SCIENCE 361, 145 (2018).
    DOI: 10.1126/science.aat0094
  • Structural Basis of Formation of the Microtubule Minus-End-Regulating CAMSAP-Katanin Complex Jiang K, Faltova L, Hua S, Capitani G, Prota Andrea E, Landgraf C, Volkmer R, Kammerer Richard A, Steinmetz Michel O, Akhmanova A
    STRUCTURE -, S0969212617304422 (2018).
    DOI: 10.1016/j.str.2017.12.017
  • Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents. Brindisi M, Ulivieri C, Alfano G, Gemma S, de Asis Balaguer F, Khan T, Grillo A, Chemi G, Menchon G, Prota AE, Olieric N, Lucena-Agell D, Barasoain I, Diaz JF, Nebbioso A, Conte M, Lopresti L, Magnano S, Amet R, Kinsella P, Zisterer DM, Ibrahim O, OSullivan J, Morbidelli L, Spaccapelo R, Baldari C, Butini S, Novellino E, Campiani G, Altucci L, Steinmetz MO, Brogi S
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 162, 290 (2018).
  • Sustainable Syntheses of (-)-Jerantinines A & E and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site Smedley Christopher J, Stanley Paul A, Qazzaz Mohannad E, Prota Andrea E, Olieric N, Collins H, Eastman H, Barrow Andrew S, Lim K, Kam T, Smith Brian J, Duivenvoorden Hendrika M, Parker Belinda S, Bradshaw Tracey D, Steinmetz Michel O, Moses John E
    Scientific Reports 8, 10617 (2018).
    DOI: 10.1038/s41598-018-28880-2

2017

  • A new inhibitor of the beta-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling Beautrait A, Paradis Justine S, Zimmerman B, Giubilaro J, Nikolajev L, Armando S, Kobayashi H, Yamani L, Namkung Y, Heydenreich Franziska M, Khoury E, Audet M, Roux Philippe P, Veprintsev Dmitry B, Laporte Stéphane A, Bouvier M
    NATURE COMMUNICATIONS 8, 15054 (2017).
    DOI: 10.1038/ncomms15054
  • A structural model for microtubule minus-end recognition and protection by CAMSAP proteins Atherton J, Jiang K, Stangier M, Luo Y, Hua S, Houben K, van Hooff J, Joseph A, Scarabelli G, Grant B, Roberts A, Topf M, Steinmetz M, Baldus M, Moores C, Akhmanova A
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 24, 931 (2017).
    DOI: 10.1038/nsmb.3483
  • Antivascular and antitumor properties of the tubulin-binding chalcone TUB091 Canela M, Noppen S, Bueno O, Prota A, Bargsten K, Sáez-Calvo G, Jimeno M, Benkheil M, Ribatti D, Velázquez S, Camarasa M, Díaz JFernando, Steinmetz MO, Priego E, Pérez-Pérez M, Liekens S
    ONCOTARGET 8, 14325 (2017).
    DOI: 10.18632/oncotarget.9527
  • Baculovirus-based genome editing in primary cells Mansouri M, Ehsaei Z, Taylor V, Berger P
    PLASMID 90, 5 (2017).
    DOI: 10.1016/j.plasmid.2017.01.003
  • Characterization at the level of individual crystals: single crystal MFI type zeolite grains Gruene T, Li T, van Genderen E, Pinar AB, van Bokhoven JA
    CHEMISTRY - A EUROPEAN JOURNAL 24, 2384 (2017).
    DOI: 10.1002/chem.201704213
  • Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent. Jost M, Chen Y, Gilbert LA, Horlbeck MA, Krenning L, Menchon G, Rai A, Cho MY, Stern JJ, Prota AE, Kampmann M, Akhmanova A, Steinmetz MO, Tanenbaum ME, Weissman JS
    MOLECULAR CELL Oct 5;68(1), 210 (2017).
    DOI: 10.1016/j.molcel.2017.09.012
  • Comprehensive Analysis of the Role of Arrestin Residues in Receptor Binding Haider Raphael S, Rizk A, Schertler G, Ostermaier M
    Springer International Publishing -, 83 (2017).
    DOI: 10.1007/978-3-319-57553-7_7
  • Crystal structure of the BoNT/A2 receptor-binding domain in complex with the luminal domain of its neuronal receptor SV2C Benoit RM, Schaerer MA, Wieser MM, Li X, Frey D, Kammerer RA
    Scientific Reports 7, 43588 (2017).
    DOI: 10.1038/srep43588
  • Deconvolution of Buparlisib?s mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention Bohnacker T, Prota AE, Beaufils F, Burke John E, Melone A, Inglis Alison J, Rageot D, Sele Alexander M, Cmiljanovic V, Cmiljanovic N, Bargsten K, Aher A, Akhmanova A, Díaz JFernando, Fabbro D, Zvelebil M, Williams Roger L, Steinmetz MO, Wymann Matthias P
    NATURE COMMUNICATIONS 8, 14683 (2017).
    DOI: 10.1038/ncomms14683
  • Identification of Chlamydomonas Central Core Centriolar Proteins Reveals a Role for Human WDR90 in Ciliogenesis Hamel V, Steib E, Hamelin R, Armand F, Borgers S, Flückiger I, Busso C, Olieric N, Sorzano Carlos Oscar S, Steinmetz Michel O, Guichard P, Gönczy P
    CURRENT BIOLOGY 27, 2486 (2017).
    DOI: 10.1016/j.cub.2017.07.011
  • Kinesin-4 KIF21B is a potent microtubule pausing factor van Riel W, Rai A, Bianchi S, Katrukha E, Liu Q, Heck A, Hoogenraad C, Steinmetz M, Kapitein L, Akhmanova A
    ELIFE 6, - (2017).
    DOI: 10.7554/eLife.24746
  • Mastering the magnetic susceptibility of magnetically responsive bicelles with 3?-amino-5-cholestene and complexed lanthanide ions Isabettini S, Liebi M, Kohlbrecher J, Ishikawa T, Fischer P, Windhab Erich J, Walde P, Kuster S
    PHYSICAL CHEMISTRY CHEMICAL PHYSICS 19, 10820 (2017).
    DOI: 10.1039/C7CP01025G
  • Methods for Generating Highly Magnetically Responsive Lanthanide-Chelating Phospholipid Polymolecular Assemblies Isabettini S, Baumgartner Mirjam E, Reckey Pernille Q, Kohlbrecher J, Ishikawa T, Fischer P, Windhab Erich J, Kuster S
    LANGMUIR 33, 6363 (2017).
    DOI: 10.1021/acs.langmuir.7b00725
  • Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex. Jiang K, Rezabkova L, Hua S, Liu Q, Capitani G, Maarten Altelaar AF, Heck AJR, Kammerer RA, Steinmetz MO, Akhmanova A
    NATURE CELL BIOLOGY 19, 480 (2017).
    DOI: 10.1038/NCB3511
  • Molecular engineering of lanthanide ion chelating phospholipids generating assemblies with a switched magnetic susceptibility Isabettini S, Massabni S, Hodzic A, Durovic D, Kohlbrecher J, Ishikawa T, Fischer P, Windhab Erich J, Walde P, Kuster S
    Phys. Chem. Chem. Phys. 19, 20991 (2017).
    DOI: 10.1039/C7CP03994H
  • OMNY PIN - A versatile sample holder for tomographic measurements at room and cryogenic temperatures Holler M, Raabe J, Wepf R, Shahmoradian SH, Diaz A, Sarafimov B, Lachat T, Walther H, Vitins M
    REVIEW OF SCIENTIFIC INSTRUMENTS 88, 113701 (2017).
    DOI: 10.1063/1.4996092
  • Perspective: Opportunities for ultrafast science at SwissFEL Abela Rafael, Beaud Paul, van Bokhoven Jeroen A, Chergui Majed, Feurer Thomas, Haase Johannes, Ingold Gerhard, Johnson Steven L, Knopp Gregor, Lemke Henrik, Milne Chris J, Pedrini Bill, Radi Peter, Schertler Gebhard, Standfuss Jorg, Staub Urs, Patthey Luc
    STRUCTURAL DYNAMICS 4, 061602 (2017).
    DOI: 10.1063/1.4997222
  • Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. Lindner R, Hartmann E, Tarnawski M, Winkler A, Frey D, Reinstein J, Meinhart A, Schlichting I
    JOURNAL OF MOLECULAR BIOLOGY 429, 1336 (2017).
    DOI: 10.1016/J.JMB.2017.03.020
  • Production and purification of human Hsp90? in Escherichia coli Radli M, Veprintsev Dmitry B, Rüdiger Stefan GD
    PLOS ONE 12, e0180047 (2017).
    DOI: 10.1371/journal.pone.0180047
  • Protein structure determination by electron diffraction using a single three-dimensional nanocrystal Clabbers MTB, van Genderen E, Wan W, Wiegers EL, Gruene T, Abrahams JP
    Acta Crystallographica Section D Structural Biology 73, 738 (2017).
    DOI: 10.1107/S2059798317010348
  • Quinolin-6-Yloxyacetamides Are Microtubule Destabilizing Agents That Bind to the Colchicine Site of Tubulin Sharma A, Sáez-Calvo G, Olieric N, de Asís Balaguer F, Barasoain I, Lamberth C, Díaz J, Steinmetz M
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 18, 1336 (2017).
    DOI: 10.3390/ijms18071336
  • Role of the nucleotidyl cyclase helical domain in catalytically active dimer formation. Vercellino I, Rezabkova L, Olieric V, Polyhach Y, Weinert T, Kammerer RA, Jeschke G, Korkhov VM
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 114, E9821 (2017).
    DOI: 10.1073/PNAS.1712621114
  • Selectivity determinants of GPCR?G-protein binding Flock T, Hauser Alexander S, Lund N, Gloriam David E, Balaji S, Babu M Madan
    NATURE 545, 317 (2017).
    DOI: 10.1038/nature22070
  • Self-assembled alpha-Tocopherol Transfer Protein Nanoparticles Promote Vitamin E Delivery Across an Endothelial Barrier. Aeschimann W, Staats S, Kammer S, Olieric N, Jeckelmann JM, Fotiadis D, Netscher T, Rimbach G, Cascella M, Stocker A
    Scientific Reports 7, 4970 (2017).
    DOI: 10.1038/S41598-017-05148-9
  • Serial crystallography at synchrotrons and X-ray lasers Standfuss J, Spence J
    IUCRJ 4, 100 (2017).
  • Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons Weinert T, Olieric N, Cheng R, Brünle S, James D, Ozerov D, Gashi D, Vera L, Marsh M, Jaeger K, Dworkowski F, Panepucci E, Basu S, Skopintsev P, Doré Andrew S, Geng T, Cooke Robert M, Liang M, Prota Andrea E, Panneels V, Nogly P, Ermler U, Schertler G, Hennig M, Steinmetz Michel O, Wang M, Standfuss J
    NATURE COMMUNICATIONS 8, 542 (2017).
    DOI: 10.1038/s41467-017-00630-4
  • Short Linear Sequence Motif LxxPTPh Targets Diverse Proteins to Growing Microtubule Ends. Kumar A, Manatschal C, Rai A, Grigoriev I, Degen MS, Jaussi R, Kretzschmar I, Prota AE, Volkmer R, Kammerer RA, Akhmanova A, Steinmetz MO
    STRUCTURE 25, 924 (2017).
    DOI: 10.1016/J.STR.2017.04.010
  • Structural Basis of Microtubule Stabilization by Discodermolide Prota Andrea E, Bargsten K, Redondo M, Smith III Amos B, Yang ChiaPing H, McDaid Hayley M, Paterson I, Horwitz Susan B, Díaz J, Steinmetz Michel O
    CHEMBIOCHEM , (2017).
    DOI: 10.1002/cbic.201600696
  • Structural Basis of cis- and trans-Combretastatin Binding to Tubulin Gaspari R, Prota Andrea E, Bargsten K, Cavalli A, Steinmetz Michel O
    Chem 2, 102 (2017).
    DOI: 10.1016/j.chempr.2016.12.005
  • Structural basis of katanin p60:p80 complex formation Rezabkova L, Jiang K, Capitani G, Prota Andrea E, Akhmanova A, Steinmetz Michel O, Kammerer Richard A
    Scientific Reports 7, 14893 (2017).
    DOI: 10.1038/s41598-017-14194-2
  • Structural biology Signalling under the microscope Tsai ChingJu, Standfuss Joerg, Glaeser Robert M
    NATURE 546, 36-37 (2017).
    DOI: 10.1038/nature22491
  • Structure of the Full-length VEGFR-1 Extracellular Domain in Complex with VEGF-A. Markovic-Mueller S, Stuttfeld E, Asthana M, Weinert T, Bliven S, Goldie KN, Kisko K, Capitani G, Ballmer-Hofer K
    STRUCTURE 25, 341 (2017).
    DOI: 10.1016/J.STR.2016.12.012
  • The DRF motif of CXCR6 as chemokine receptor adaptation to adhesion Eugenin Eliseo A, Koenen A, Babendreyer A, Schumacher J, Pasqualon T, Schwarz N, Seifert A, Deupi X, Ludwig A, Dreymueller D
    PLOS ONE 12, e0173486 (2017).
    DOI: 10.1371/journal.pone.0173486
  • Three-Dimensional Imaging of Biological Tissue by Cryo X-Ray Ptychography Shahmoradian SH, Tsai EHR, Diaz A, Guizar-Sicairos M, Raabe J, Spycher L, Britschgi M, Ruf A, Stahlberg H, Holler M
    Scientific Reports 7, 6291 (2017).
    DOI: 10.1038/s41598-017-05587-4
  • Triazolopyrimidines Are Microtubule-Stabilizing Agents that Bind the Vinca Inhibitor Site of Tubulin. Saez-Calvo G, Sharma A, Balaguer FA, Barasoain I, Rodriguez-Salarichs J, Olieric N, Munoz-Hernandez H, Berbis MA, Wendeborn S, Penalva MA, Matesanz R, Canales A, Prota AE, Jimenez-Barbero J, Andreu JM, Lamberth C, Steinmetz MO, Diaz JF
    CELL CHEMICAL BIOLOGY 24, 737 (2017).
    DOI: 10.1016/J.CHEMBIOL.2017.05.016
  • Zampanolide Binding to Tubulin Indicates Cross-Talk of Taxane Site with Colchicine and Nucleotide Sites. Field JJ, Pera B, Gallego JE, Calvo E, Rodriguez-Salarichs J, Saez-Calvo G, Zuwerra D, Jordi M, Andreu JM, Prota AE, Menchon G, Miller JH, Altmann KH, Diaz JF
    JOURNAL OF NATURAL PRODUCTS , (2017).
    DOI: 10.1021/acs.jnatprod.7b00704

2016

  • A simple and fast approach for missing-wedge invariant classification of subtomograms extracted from filamentous structures Obbineni J, Yamamoto R, Ishikawa T
    JOURNAL OF STRUCTURAL BIOLOGY , (2016).
    DOI: 10.1016/j.jsb.2016.08.003
  • A three-dimensional movie of structural changes in bacteriorhodopsin Nango Eriko, Royant Antoine, Kubo Minoru, Nakane Takanori, Wickstrand Cecilia, Kimura Tetsunari, Tanaka Tomoyuki, Tono Kensuke, Song Changyong, Tanaka Rie, Arima Toshi, Yamashita Ayumi, Kobayashi Jun, Hosaka Toshiaki, Mizohata Eiichi, Nogly Przemyslaw, Sugahara Michihiro, Nam Daewoong, Nomura Takashi, Shimamura Tatsuro, Im Dohyun, Fujiwara Takaaki, Yamanaka Yasuaki, Jeon Byeonghyun, Nishizawa Tomohiro, Oda Kazumasa, Fukuda Masahiro, Andersson Rebecka, Bath Petra, Dods Robert, Davidsson Jan, Matsuoka Shigeru, Kawatake Satoshi, Murata Michio, Nureki Osamu, Owada Shigeki, Kameshima Takashi, Hatsui Takaki, Joti Yasumasa, Schertler Gebhard, Yabashi Makina, Bondar AnaNicoleta, Standfuss Jorg, Neutze Richard, Iwata So
    SCIENCE 354, 1552-1557 (2016).
    DOI: 10.1126/science.aah3497
  • Ab initio structure determination of nanocrystals of organic pharmaceutical compounds by electron diffraction at room temperature using a Timepix quantum area direct electron detector van Genderen E, Clabbers MTB, Das PP, Stewart A, Nederlof I, Barentsen KC, Portillo Q, Pannu NS, Nicolopoulos S, Gruene T, Abrahams JP
    Acta Crystallographica Section A Foundations and Advances 72, 236 (2016).
    DOI: 10.1107/S2053273315022500
  • Accelerating the Association of the Most Stable Protein-Ligand Complex by more than Two Orders of Magnitude Giese C, Eras J, Kern A, Schärer Martin A, Capitani G, Glockshuber R
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION , (2016).
    DOI: 10.1002/anie.201603652
  • Addendum to Three-dimensional mass density mapping of cellular ultrastructure by ptychographic X-ray nanotomography [J. Struct. Biol. 192 (2015) 461-469] Diaz A, Malkova B, Holler M, Guizar-Sicairos M, Lima E, Panneels V, Pigino G, Bittermann A, Wettstein L, Tomizaki T, Bunk O, Schertler G, Ishikawa T, Wepf R, Menzel A
    JOURNAL OF STRUCTURAL BIOLOGY 193, 83 (2016).
    DOI: 10.1016/j.jsb.2015.12.003
  • Backbone NMR reveals allosteric signal transduction networks in the beta1-adrenergic receptor Isogai S, Deupi X, Opitz C, Heydenreich Franziska M, Tsai C, Brueckner F, Schertler Gebhard FX, Veprintsev Dmitry B, Grzesiek S
    NATURE 530, 237 (2016).
    DOI: 10.1038/nature16577
  • Biochemie und Molekularbiologie Christen P, Jaussi R, Benoit R
    Springer Verlag Berlin Heidelberg , (2016).
    DOI: 10.1007/978-3-662-46430-4_1
  • Biophysical and Structural Characterization of the Centriolar Protein Cep104 Interaction Network. Rezabkova L, Kraatz SH, Akhmanova A, Steinmetz MO, Kammerer RA
    JOURNAL OF BIOLOGICAL CHEMISTRY 291, 18496 (2016).
    DOI: 10.1074/JBC.M116.739771
  • Centriolar CPAP/SAS-4 Imparts Slow Processive Microtubule Growth Sharma Ashwani, Aher Amol, Dynes Nicola J, Frey Daniel, Katrukha Eugene A, Jaussi Rolf, Grigoriev Ilya, Croisier Marie, Kammerer Richard A, Akhmanova Anna, Gonczy Pierre, Steinmetz Michel O
    DEVELOPMENTAL CELL 37, 362-376 (2016).
    DOI: 10.1016/j.devcel.2016.04.024
  • Characterization of Mn(II) ion binding to the amyloid-? peptide in Alzheimer?s disease Wallin C, Kulkarni Yashraj S, Abelein A, Jarvet J, Liao Q, Strodel B, Olsson L, Luo J, Abrahams J, Sholts Sabrina B, Roos Per M, Kamerlin Shina CL, Gräslund A, Wärmländer Sebastian KTS
    JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY , (2016).
    DOI: 10.1016/j.jtemb.2016.03.009
  • Control of the structural landscape and neuronal proteotoxicity of mutant Huntingtin by domains flanking the polyQ tract Shen K, Calamini B, Fauerbach J, Ma B, Shahmoradian S, Serrano Lachapel I, Chiu W, Lo D, Frydman J
    ELIFE 5, (2016).
    DOI: 10.7554/eLife.18065
  • Cross-interactions between the Alzheimer Disease Amyloid-? Peptide and Other Amyloid Proteins: A Further Aspect of the Amyloid Cascade Hypothesis Luo J, Wärmländer Sebastian KTS, Gräslund A, Abrahams J
    JOURNAL OF BIOLOGICAL CHEMISTRY 291, 16485 (2016).
    DOI: 10.1074/jbc.R116.714576
  • Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies Burger Dominique, Stihle Martine, Sharma Ashwani, Di Lello Paola, Benz Jorg, D'Arcy Brigitte, Debulpaep Maja, Fry David, Huber Walter, Kremer Thomas, Laeremans Toon, Matile Hugues, Ross Alfred, Rufer Arne C, Schoch Guillaume, Steinmetz Michel O, Steyaert Jan, Rudolph Markus G, Thoma Ralf, Ruf Armin
    JOURNAL OF BIOLOGICAL CHEMISTRY 291, 16292-16306 (2016).
    DOI: 10.1074/jbc.M116.726547
  • Data-collection strategy for challenging native SAD phasing Olieric V, Weinert T, Finke Aaron D, Anders C, Li D, Olieric N, Borca Camelia N, Steinmetz Michel O, Caffrey M, Jinek M, Wang M
    ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY 72, 421 (2016).
    DOI: 10.1107/S2059798315024110
  • Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region Venkatakrishnan AJ, Deupi X, Lebon G, Heydenreich Franziska M, Flock T, Miljus T, Balaji S, Bouvier M, Veprintsev Dmitry B, Tate Christopher G, Schertler G FX, Babu MMadan
    NATURE 536, 484 (2016).
    DOI: 10.1038/nature19107
  • EB1 interacts with outwardly curved and straight regions of the microtubule lattice Guesdon A, Bazile F, Buey RM, Mohan R, Monier S, García R, Angevin M, Heichette C, Wieneke R, Tampé R, Duchesne L, Akhmanova A, Steinmetz MO, Chrétien D
    NATURE CELL BIOLOGY 18, 1102 (2016).
    DOI: 10.1038/ncb3412
  • Functional map of arrestin binding to phosphorylated opsin, with and without agonist Peterhans C, Lally Ciara CM, Ostermaier Martin K, Sommer Martha E, Standfuss J
    Scientific Reports 6, 28686 (2016).
    DOI: 10.1038/srep28686
  • Functional map of arrestin binding to phosphorylated opsin, with and without agonist (vol 6, 28686, 2016) Peterhans Christian, Lally Ciara C M, Ostermaier Martin K, Sommer Martha E, Standfuss Jorg
    Scientific Reports 6, 30224 (2016).
    DOI: 10.1038/srep30224
  • Highly efficient baculovirus-mediated multigene delivery in primary cells Mansouri M, Bellon-Echeverria I, Rizk A, Ehsaei Z, Cianciolo Cosentino C, Silva Catarina S, Xie Y, Boyce Frederick M, Davis MWayne, Neuhauss Stephan CF, Taylor V, Ballmer-Hofer K, Berger I, Berger P
    NATURE COMMUNICATIONS 7, 11529 (2016).
    DOI: 10.1038/ncomms11529
  • In meso in situ In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures Huang ChiaYing, Olieric Vincent, Ma Pikyee, Howe Nicole, Vogeley Lutz, Liu Xiangyu, Warshamanage Rangana, Weinert Tobias, Panepucci Ezequiel, Kobilka Brian, Diederichs Kay, Wang Meitian, Caffrey Martin
    ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY 72, 93-112 (2016).
    DOI: 10.1107/S2059798315021683
  • In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures. Huang CY, Olieric V, Ma P, Howe N, Vogeley L, Liu X, Warshamanage R, Weinert T, Panepucci E, Kobilka B, Diederichs K, Wang M, Caffrey M
    ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 72, 93 (2016).
    DOI: 10.1107/S2059798315021683
  • Kinesin-Binding Protein Controls Microtubule Dynamics and Cargo Trafficking by Regulating Kinesin Motor Activity Kevenaar Josta T, Bianchi S, van Spronsen M, Olieric N, Lipka J, Frias Cátia P, Mikhaylova M, Harterink M, Keijzer N, Wulf Phebe S, Hilbert M, Kapitein Lukas C, de Graaff E, Ahkmanova A, Steinmetz Michel O, Hoogenraad Casper C
    CURRENT BIOLOGY 26, 849 (2016).
    DOI: 10.1016/j.cub.2016.01.048
  • Lattice filter for processing image data of three-dimensional protein nanocrystals van Genderen E, Li YW, Nederlof I, Abrahams JP
    ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY 72, 34 (2016).
    DOI: 10.1107/S205979831502149X
  • Lipidic cubic phase injector is a viable crystal delivery system for time-resolved serial crystallography Nogly P, Panneels V, Nelson G, Gati C, Kimura T, Milne C, Milathianaki D, Kubo M, Wu W, Conrad C, Coe J, Bean R, Zhao Y, Båth P, Dods R, Harimoorthy R, Beyerlein Kenneth R, Rheinberger J, James D, DePonte D, Li C, Sala L, Williams Garth J, Hunter Mark S, Koglin Jason E, Berntsen P, Nango E, Iwata S, Chapman Henry N, Fromme P, Frank M, Abela R, Boutet S, Barty A, White Thomas A, Weierstall U, Spence J, Neutze R, Schertler G, Standfuss J
    NATURE COMMUNICATIONS 7, 12314 (2016).
    DOI: 10.1038/ncomms12314
  • Modern X-ray analysis on single crystals - a practical guide Gruene T
    Crystallography Reviews 22, 287 (2016).
    DOI: 10.1080/0889311X.2016.1237508
  • Molecular basis of Kar9-Bim1 complex function during mating and spindle positioning Manatschal C, Farcas AM, Degen MS, Bayer M, Kumar A, Landgraf C, Volkmer R, Barral Y, Steinmetz MO
    MOLECULAR BIOLOGY OF THE CELL 27, 3729 (2016).
    DOI: 10.1091/mbc.E16-07-0552
  • Pironetin Binds Covalently to alpha Cys316 and Perturbs a Major Loop and Helix of alpha-Tubulin to Inhibit Microtubule Formation. Prota AE, Setter J, Waight AB, Bargsten K, Murga J, Diaz JF, Steinmetz MO
    JOURNAL OF MOLECULAR BIOLOGY 428, 2981 (2016).
    DOI: 10.1016/J.JMB.2016.06.023
  • Reciprocal Molecular Interactions between the A? Peptide Linked to Alzheimer?s Disease and Insulin Linked to Diabetes Mellitus Type II Luo J, Wärmländer Sebastian KTS, Gräslund A, Abrahams J
    ACS Chemical Neuroscience 7, 269 (2016).
    DOI: 10.1021/acschemneuro.5b00325
  • Recreating the synthesis of starch granules in yeast Pfister B, Sánchez-Ferrer A, Diaz A, Lu K, Otto C, Holler M, Shaik F, Meier F, Mezzenga R, Zeeman S
    ELIFE 5, e15552 (2016).
    DOI: 10.7554/eLife.15552
  • SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture Hilbert Manuel, Noga Akira, Frey Daniel, Hamel Virginie, Guichard Paul, Kraatz Sebastian H W, Pfreundschuh Moritz, Hosner Sarah, Flueckiger Isabelle, Jaussi Rolf, Wieser Mara M, Thieltges Katherine M, Deupi Xavier, Mueller Daniel J, Kammerer Richard A, Goenczy Pierre, Hirono Masafumi, Steinmetz Michel O
    NATURE CELL BIOLOGY 18, 393-+ (2016).
    DOI: 10.1038/ncb3329
  • Seamless Insert-Plasmid Assembly at High Efficiency and Low Cost Benoit RM, Ostermeier C, Geiser M, Li JSZ, Widmer H, Auer M
    PLOS ONE 11, e0153158 (2016).
    DOI: 10.1371/journal.pone.0153158
  • Serial Millisecond Crystallography of Membrane Proteins Jaeger K, Dworkowski F, Nogly P, Milne C, Wang M, Standfuss J
    ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY 922, 137 (2016).
    DOI: 10.1007/978-3-319-35072-1_10
  • Structural Basis of Microtubule Destabilization by Potent Auristatin Anti-Mitotics Waight AB, Bargsten K, Doronina S, Steinmetz MO, Sussman D, Prota AE
    PLOS ONE 11, e0160890 (2016).
    DOI: 10.1371/journal.pone.0160890
  • Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells Trigili C, Barasoain I, Sánchez-Murcia Pedro A, Bargsten K, Redondo-Horcajo M, Nogales A, Gardner Nicola M, Meyer A, Naylor Guy J, Gómez-Rubio E, Gago F, Steinmetz Michel O, Paterson I, Prota Andrea E, Díaz JFernando
    ACS Omega 1, 1192 (2016).
    DOI: 10.1021/acsomega.6b00317
  • Structural basis for misregulation of kinesin KIF21A autoinhibition by CFEOM1 disease mutations Bianchi S, van Riel Wilhelmina E, Kraatz Sebastian HW, Olieric N, Frey D, Katrukha Eugene A, Jaussi R, Missimer J, Grigoriev I, Olieric V, Benoit Roger M, Steinmetz Michel O, Akhmanova A, Kammerer Richard A
    Scientific Reports 6, 30668 (2016).
    DOI: 10.1038/srep30668
  • Structural role of the T94I rhodopsin mutation in congenital stationary night blindness Singhal Ankita, Guo Ying, Matkovic Milos, Schertler Gebhard, Deupi Xavier, Yan Elsa C Y, Standfuss Joerg
    EMBO REPORTS 17, 1431-1440 (2016).
    DOI: 10.15252/embr.201642671
  • Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family (vol 22, pg 303, 2015) Geertsma Eric R, Chang YungNing, Shaik Farooque R, Neldner Yvonne, Pardon Els, Steyaert Jan, Dutzler Raimund
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 23, 462-462 (2016).
  • TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington?s disease Zhao X, Chen X, Han E, Hu Y, Paik P, Ding Z, Overman J, Lau Alice L, Shahmoradian SH, Chiu W, Thompson Leslie M, Wu C, Mobley William C
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 113, E5655 (2016).
    DOI: 10.1073/pnas.1603020113
  • Tailoring Bicelle Morphology and Thermal Stability with Lanthanide-Chelating Cholesterol Conjugates Isabettini S, Liebi M, Kohlbrecher J, Ishikawa T, Windhab Erich J, Fischer P, Walde P, Kuster S
    LANGMUIR 32 (35), 9005 (2016).
    DOI: 10.1021/acs.langmuir.6b01968
  • Termination of Protofilament Elongation by Eribulin Induces Lattice Defects that Promote Microtubule Catastrophes Doodhi Harinath, Prota Andrea E, Rodriguez-Garcia Ruddi, Xiao Hui, Custar Daniel W, Bargsten Katja, Katrukha Eugene A, Hilbert Manuel, Hua Shasha, Jiang Kai, Grigoriev Ilya, Yang ChiaPing H, Cox David, Horwitz Susan Band, Kapitein Lukas C, Akhmanova Anna, Steinmetz Michel O
    CURRENT BIOLOGY 26, 1713-1721 (2016).
    DOI: 10.1016/j.cub.2016.04.053
  • The Human Centriolar Protein CEP135 Contains a Two-Stranded Coiled-Coil Domain Critical for Microtubule Binding Kraatz S, Guichard P, Obbineni Jagan M, Olieric N, Hatzopoulos Georgios N, Hilbert M, Sen I, Missimer J, Gönczy P, Steinmetz Michel O
    STRUCTURE 24, 1358 (2016).
    DOI: 10.1016/j.str.2016.06.011
  • The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity Wieczorek Michal, Tcherkezian Joseph, Bernier Cynthia, Prota AE, Chaaban Sami, Rolland Yanneve, Godbout Claude, Hancock Mark A, Arezzo Joseph C, Ocal Ozhan, Rocha Cecilia, Olieric N, Hall Anita, Ding Hui, Bramoulle Alexandre, Annis Matthew G, Zogopoulos George, Harran Patrick G, Wilkie Thomas M, Brekken Rolf A, Siegel Peter M, Steinmetz MO, Shore Gordon C, Brouhard Gary J, Roulston Anne
    SCIENCE TRANSLATIONAL MEDICINE 8, 365ra159 (2016).
    DOI: 10.1126/scitranslmed.aag1093
  • Three-dimensional mass density mapping of cellular ultrastructure by ptychographic X-ray nanotomography (vol 192, pg 461, 2015) Diaz Ana, Malkova Barbora, Holler Mirko, Guizar-Sicairos Manuel, Lima Enju, Panneels Valerie, Pigino Gaia, Bittermann Anne Greet, Wettstein Larissa, Tomizaki Takashi, Bunk Oliver, Schertler Gebhard, Ishikawa Takashi, Wepf Roger, Menzel Andreas
    JOURNAL OF STRUCTURAL BIOLOGY 193, 83-83 (2016).
    DOI: 10.1016/j.jsb.2015.12.003
  • Understanding the fabric of protein crystals: computational classification of biological interfaces and crystal contacts Capitani G, Duarte Jose M, Baskaran K, Bliven S, Somody Joseph C
    BIOINFORMATICS 32, 481 (2016).
    DOI: 10.1093/bioinformatics/btv622

2015

  • A Molecular Pharmacologist's Guide to G Protein-Coupled Receptor Crystallography Piscitelli CL, Kean J, de Graaf C, Deupi X
    MOLECULAR PHARMACOLOGY 88, 536 (2015).
    DOI: 10.1124/mol.115.099663
  • A posteriori correction of camera characteristics from large image data sets Afanasyev P, Ravelli Raimond BG, Matadeen R, De Carlo S, van Duinen G, Alewijnse B, Peters Peter J, Abrahams J, Portugal Rodrigo V, Schatz M, van Heel M
    Scientific Reports 5, 10317 (2015).
    DOI: 10.1038/srep10317
  • Batch crystallization of rhodopsin for structural dynamics using an X-ray free-electron laser Wu W, Nogly P, Rheinberger J, M Kick L, Gati C, Nelson G, Deupi X, Standfuss J, Schertler G, Panneels V
    ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS 71, 856 (2015).
    DOI: 10.1107/S2053230X15009966
  • Bilayer Properties of 1,3-Diamidophospholipids Weinberger A, Tanasescu R, Stefaniu C, Fedotenko lllya A, Favarger F, Ishikawa T, Brezesinski G, Marques Carlos M, Zumbuehl A
    LANGMUIR 31, 1879 (2015).
    DOI: 10.1021/la5041745
  • Control of microtubule organization and dynamics: two ends in the limelight Akhmanova A, Steinmetz Michel O
    NATURE REVIEWS MOLECULAR CELL BIOLOGY 16, 711 (2015).
    DOI: 10.1038/nrm4084
  • Cryo-electron tomography of motile cilia and flagella Ishikawa T
    Cilia 4, 3 (2015).
    DOI: 10.1186/s13630-014-0012-7
  • Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser Kang Y, Zhou XEdward, Gao X, He Y, Liu W, Ishchenko A, Barty A, White Thomas A, Yefanov O, Han G, Xu Q, de Waal Parker W, Ke J, Tan MHEileen, Zhang C, Moeller A, West Graham M, Pascal Bruce D, Van Eps N, Caro Lydia N, Vishnivetskiy Sergey A, Lee Regina J, Suino-Powell Kelly M, Gu X, Pal K, Ma J, Zhi X, Boutet S, Williams Garth J, Messerschmidt M, Gati C, Zatsepin Nadia A, Wang D, James D, Basu S, Roy-Chowdhury S, Conrad Chelsie E, Coe J, Liu H, Lisova S, Kupitz C, Grotjohann I, Fromme R, Jiang Y, Tan M, Yang H, Li J, Wang M, Zheng Z, Li D, Howe N, Zhao Y, Standfuss J, Diederichs K, Dong Y, Potter Clinton S, Carragher B, Caffrey M, Jiang H, Chapman Henry N, Spence John CH, Fromme P, Weierstall U, Ernst Oliver P, Katritch V, Gurevich Vsevolod V, Griffin Patrick R, Hubbell Wayne L, Stevens Raymond C, Cherezov V, Melcher K, Xu HEric
    NATURE 523, 561 (2015).
    DOI: 10.1038/nature14656
  • Design of magnetically responsive phospholipid bicelles towards switchable optical hydrogels Liebi M, Kuster S, Kohlbrecher J, Ishikawa T, Walde P, Windhab EJ, Fischer P
    Swiss Neutron News 45, 4 (2015).
  • Electron crystallography of 3D nano-crystals Clabbers Max TB, van Genderen E, Nederlof I, Li Y, Abrahams J
    Acta Crystallographica Section A Foundations and Advances 71, s405 (2015).
    DOI: 10.1107/S2053273315093985
  • Electron diffraction and imaging of 3D nanocrystals of pharmaceuticals, peptides and proteins Abrahams J, van Genderen E, Nederlof I, Clabbers M, Li Y
    Acta Crystallographica Section A Foundations and Advances 71, s103 (2015).
    DOI: 10.1107/S2053273315098496
  • Fast native-SAD phasing for routine macromolecular structure determination Weinert Tobias, Olieric Vincent, Waltersperger Sandro, Panepucci Ezequiel, Chen Lirong, Zhang Hua, Zhou Dayong, Rose John, Ebihara Akio, Kuramitsu Seiki, Li Dianfan, Howe Nicole, Schnapp Gisela, Pautsch Alexander, Bargsten Katja, Prota Andrea E, Surana Parag, Kottur Jithesh, Nair Deepak T, Basilico Federica, Cecatiello Valentina, Pasqualato Sebastiano, Boland Andreas, Weichenrieder Oliver, Wang Bi-Cheng, Steinmetz Michel O, Caffrey Martin, Wang Meitian
    NATURE METHODS 12, 131-U163 (2015).
    DOI: 10.1038/nmeth.3211
  • Fast native-SAD phasing for routine macromolecular structure determination (vol 12, pg 131, 2015) Weinert Tobias, Olieric Vincent, Waltersperger Sandro, Panepucci Ezequiel, Chen Lirong, Zhang Hua, Zhou Dayong, Rose John, Ebihara Akio, Kuramitsu Seiki, Li Dianfan, Howe Nicole, Schnapp Gisela, Pautsch Alexander, Bargsten Katja, Prota Andrea E, Surana Parag, Kottur Jithesh, Nair Deepak T, Basilico Federica, Cecatiello Valentina, Pasqualato Sebastiano, Boland Andreas, Weichenrieder Oliver, Wang BiCheng, Steinmetz Michel O, Caffrey Martin, Wang Meitian
    NATURE METHODS 12, 692-692 (2015).
  • Functional roles of the hexamer organization of plant glutamate decarboxylase Astegno A, Capitani G, Dominici P
    BIOCHIMICA ET BIOPHYSICA ACTA (BBA) - PROTEINS AND PROTEOMICS 1854, 1229 (2015).
    DOI: 10.1016/j.bbapap.2015.01.001
  • In meso in situ serial X-ray crystallography of soluble and membrane proteins Huang Chia-Ying, Olieric Vincent, Ma Pikyee, Panepucci Ezequiel, Diederichs Kay, Wang Meitian, Caffrey Martin
    ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 71, 1238-1256 (2015).
    DOI: 10.1107/S1399004715005210
  • Large scale expression and purification of the rat 5-HT2c receptor He X, Robertson N, Jazayeri A, Gasperina A, Schertler G, Li X
    PROTEIN EXPRESSION AND PURIFICATION 106, 1 (2015).
    DOI: 10.1016/j.pep.2014.10.010
  • Large-scale production and protein engineering of G protein-coupled receptors for structural studies Milic D, Veprintsev Dmitry B
    Frontiers in Pharmacology 6, 66 (2015).
    DOI: 10.3389/fphar.2015.00066
  • Light-driven Na+ pumps as next-generation inhibitory optogenetic tools Nogly P, Standfuss J
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 22, 351 (2015).
    DOI: 10.1038/nsmb.3017
  • Lipidic cubic phase serial millisecond crystallography using synchrotron radiation Nogly Przemyslaw, James Daniel, Wang Dingjie, White Thomas A, Zatsepin Nadia, Shilova Anastasya, Nelson Garrett, Liu Haiguang, Johansson Linda, Heymann Michael, Jaeger Kathrin, Metz Markus, Wickstrand Cecilia, Wu Wenting, Bath Petra, Berntsen Peter, Oberthuer Dominik, Panneels Valerie, Cherezov Vadim, Chapman Henry, Schertler Gebhard, Neutze Richard, Spence John, Moraes Isabel, Burghammer Manfred, Standfuss Joerg, Weierstall Uwe
    IUCRJ 2, 168-176 (2015).
    DOI: 10.1107/S2052252514026487
  • Low-Z polymer sample supports for fixed-target serial femtosecond X-ray crystallography Feld Geoffrey K, Heymann Michael, Benner W Henry, Pardini Tommaso, Tsai ChingJu, Boutet Sebastien, Coleman Matthew A, Hunter Mark S, Li Xiaodan, Messerschmidt Marc, Opathalage Achini, Pedrini Bill, Williams Garth J, Krantz Bryan A, Fraden Seth, Hau-Riege Stefan, Evans James E, Segelke Brent W, Frank Matthias
    JOURNAL OF APPLIED CRYSTALLOGRAPHY 48, 1072-1079 (2015).
    DOI: 10.1107/S1600576715010493
  • Mammalian Expression, Purification, and Crystallization of Rhodopsin Variants Mattle D, Singhal A, Schmid G, Dawson R, Standfuss J
    Methods in Molecular Biology 1271, 39 (2015).
    DOI: 10.1007/978-1-4939-2330-4_3
  • Optochemistry to control the microtubule cytoskeleton Janke C, Steinmetz MO
    The EMBO Journal 34, 2114 (2015).
    DOI: 10.15252/embj.201592415
  • Probing Galpha_i1 protein activation at single?amino acid resolution Sun D, Flock T, Deupi X, Maeda S, Matkovic M, Mendieta S, Mayer D, Dawson R, Schertler G, Babu M, Veprintsev D
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 22, 686 (2015).
    DOI: 10.1038/nsmb.3070
  • RAFT synthesis of poly(vinylpyrrolidone) amine and preparation of a water-soluble C 60 -PVP conjugate Aroua S, Tiu Elisha Gabrielle V, Ayer M, Ishikawa T, Yamakoshi Y
    Polym. Chem. 6, 2616 (2015).
    DOI: 10.1039/C4PY01333F
  • Stabilization of G protein-coupled receptors by point mutations Heydenreich Franziska M, Vuckovic Z, Matkovic M, Veprintsev Dmitry B
    Frontiers in Pharmacology 6, 82 (2015).
    DOI: 10.3389/fphar.2015.00082
  • Structural basis of enzymatic benzene ring reduction Weinert Tobias, Huwiler Simona G, Kung Johannes W, Weidenweber Sina, Hellwig Petra, Staerk HansJoachim, Biskup Till, Weber Stefan, Cotelesage Julien J H, George Graham N, Ermler Ulrich, Boll Matthias
    NATURE CHEMICAL BIOLOGY 11, 586-U123 (2015).
    DOI: 10.1038/NCHEMBIO.1849
  • Structural basis of enzymatic benzene ring reduction (vol 11, pg 586, 2015) Weinert Tobias, Huwiler Simona G, Kung Johannes W, Weidenweber Sina, Hellwig Petra, Staerk HansJoachim, Biskup Till, Weber Stefan, Cotelesage Julien J H, George Graham N, Ermler Ulrich, Boll Matthias
    NATURE CHEMICAL BIOLOGY 11, 741-741 (2015).
  • Structural basis of enzymatic benzene ring reduction (vol 18, pg 586, 2015) Weinert Tobias, Huwiler Simona G, Kung Johannes W, Weidenweber Sina, Hellwig Petra, Staerk HansJoachim, Biskup Till, Weber Stefan, Cotelesage Julien J H, George Graham N, Ermler Ulrich, Boll Matthias
    NATURE CHEMICAL BIOLOGY 11, 815-815 (2015).
  • Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family Geertsma Eric R, Chang YungNing, Shaik Farooque R, Neldner Yvonne, Pardon Els, Steyaert Jan, Dutzler Raimund
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 22, 803-808 (2015).
    DOI: 10.1038/nsmb.3091
  • Structure of the BoNT/A1 - receptor complex Benoit Roger M, Frey D, Wieser Mara M, Thieltges Katherine M, Jaussi R, Capitani G, Kammerer Richard A
    TOXICON 107, 25 (2015).
    DOI: 10.1016/j.toxicon.2015.08.002
  • Subcellular object quantification with Squassh3C and SquasshAnalyst Rizk A, Mansouri M, Ballmer-Hofer K, Berger P
    BIOTECHNIQUES 59, (2015).
    DOI: 10.2144/000114352
  • Synthesis of Single Crystal Nanoreactor Materials with Multiple Catalytic Functions by Incipient Wetness Impregnation and Ion Exchange Fodor D, Ishikawa T, Krumeich F, van Bokhoven Jeroen A
    ADVANCED MATERIALS 27, 1919 (2015).
    DOI: 10.1002/adma.201404628
  • TMalphaDB and TMbetaDB: web servers to study the structural role of sequence motifs in alpha-helix and beta-barrel domains of membrane proteins Perea M, Lugtenburg I, Mayol E, Cordomí A, Deupí X, Pardo L, Olivella M
    BMC BIOINFORMATICS 16, 266 (2015).
    DOI: 10.1186/s12859-015-0699-5
  • The use of ene adducts to study and engineer enoyl-thioester reductases. Rosenthal RG, Vogeli B, Quade N, Capitani G, Kiefer P, Vorholt JA, Ebert MO, Erb TJ
    NATURE CHEMICAL BIOLOGY 11, 398 (2015).
    DOI: 10.1038/NCHEMBIO.1794
  • Three-dimensional mass density mapping of cellular ultrastructure by ptychographic X-ray nanotomography Diaz A, Malkova B, Holler M, Guizar-Sicairos M, Lima E, Panneels V, Pigino G, Bittermann A, Wettstein L, Tomizaki T, Bunk O, Schertler G, Ishikawa T, Wepf R, Menzel A
    JOURNAL OF STRUCTURAL BIOLOGY 192, 461 (2015).
    DOI: 10.1016/j.jsb.2015.10.008
  • Time-resolved structural studies with serial crystallography: A new light on retinal proteins Panneels Valerie, Wu Wenting, Tsai ChingJu, Nogly Przemek, Rheinberger Jan, Jaeger Kathrin, Cicchetti Gregor, Gati Cornelius, Kick Leonhard M, Sala Leonardo, Capitani Guido, Milne Chris, Padeste Celestino, Pedrini Bill, Li XiaoDan, Standfuss Joerg, Abela Rafael, Schertler Gebhard
    STRUCTURAL DYNAMICS 2, 041718 (2015).
    DOI: 10.1063/1.4922774
  • Universal allosteric mechanism for Galpha activation by GPCRs Flock T, Ravarani Charles NJ, Sun D, Venkatakrishnan AJ, Kayikci M, Tate Christopher G, Veprintsev Dmitry B, Babu MMadan
    NATURE 524, 173 (2015).
    DOI: 10.1038/nature14663
  • Viral chemokine mimicry Standfuss J
    SCIENCE 347, 1071 (2015).
    DOI: 10.1126/science.aaa7998
  • alpha- and beta-Tubulin Lattice of the Axonemal Microtubule Doublet and Binding Proteins Revealed by Single Particle Cryo-Electron Microscopy and Tomography Maheshwari A, Obbineni J, Bui K, Shibata K, Toyoshima Yoko Y, Ishikawa T
    STRUCTURE 23, 1584 (2015).
    DOI: 10.1016/j.str.2015.06.017

2014

  • 7 angstrom resolution in protein two-dimensional-crystal X-ray diffraction at Linac Coherent Light Source Pedrini Bill, Tsai Ching-Ju, Capitani Guido, Padeste Celestino, Hunter Mark S, Zatsepin Nadia A, Barty Anton, Benner W Henry, Boutet Sebastien, Feld Geoffrey K, Hau-Riege Stefan P, Kirian Richard A, Kupitz Christopher, Messerschmitt Marc, Ogren John I, Pardini Tommaso, Segelke Brent, Williams Garth J, Spence John C H, Abela Rafael, Coleman Matthew, Evans James E, Schertler Gebhard F X, Frank Matthias, Li Xiao-Dan
    PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES 369, UNSP 20130500 (2014).
    DOI: 10.1098/rstb.2013.0500
  • A Type IV Translocated Legionella Cysteine Phytase Counteracts Intracellular Growth Restriction by Phytate Weber Stephen, Stirnimann Christian U, Wieser Mara, Frey Daniel, Meier Roger, Engelhardt Sabrina, Li Xiaodan, Capitani Guido, Kammerer Richard A, Hilbi Hubert
    JOURNAL OF BIOLOGICAL CHEMISTRY 289, 34175-34188 (2014).
    DOI: 10.1074/jbc.M114.592568
  • A missense mutation in the PISA domain of HsSAS-6 causes autosomal recessive primary microcephaly in a large consanguineous Pakistani family Khan MA, Rupp VM, Orpinell M, Hussain MS, Altmuller J, Steinmetz MO, Enzinger C, Thiele H, Hohne W, Nurnberg G, Baig SM, Ansar M, Nurnberg P, Vincent JB, Speicher MR, Gonczy P, Windpassinger C
    HUMAN MOLECULAR GENETICS 23, 5940 (2014).
    DOI: 10.1093/hmg/ddu318
  • A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs Prota Andrea E, Bargsten Katja, Fernando Diaz J, Marsh May, Cuevas Carmen, Liniger Marc, Neuhaus Christian, Andreu Jose M, Altmann Karl-Heinz, Steinmetz Michel O
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111, 13817-13821 (2014).
    DOI: 10.1073/pnas.1408124111
  • Actin?microtubule coordination at growing microtubule ends López M, Huber F, Grigoriev I, Steinmetz Michel O, Akhmanova A, Koenderink Gijsje H, Dogterom M
    NATURE COMMUNICATIONS 5, 4778 (2014).
    DOI: 10.1038/ncomms5778
  • Alzheimer Peptides Aggregate into Transient Nanoglobules That Nucleate Fibrils Luo J, Wärmländer Sebastian KTS, Gräslund A, Abrahams J
    BIOCHEMISTRY 53, 6302 (2014).
    DOI: 10.1021/bi5003579
  • ChemInform Abstract: Cyclic Peptides as Inhibitors of Amyloid Fibrillation Luo J, Abrahams J
    ChemInform 45, no (2014).
    DOI: 10.1002/chin.201422265
  • Conformational transitions driven by pyridoxal-5 '-phosphate uptake in the psychrophilic Serine hydroxymethyltransferase from Psychromonas ingrahamii Angelaccio Sebastiana, Dworkowski Florian, Di Bello Angela, Milano Teresa, Capitani Guido, Pascarella Stefano
    PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 82, 2831-2841 (2014).
    DOI: 10.1002/prot.24646
  • Copper-transporting P-type ATPases use a unique ion-release pathway Andersson Magnus, Mattle Daniel, Sitsel Oleg, Klymchuk Tetyana, Nielsen Anna Marie, Moller Lisbeth Birk, White Stephen H, Nissen Poul, Gourdon Pontus
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 21, 43-+ (2014).
    DOI: 10.1038/nsmb.2721
  • Coronin 1 Regulates Cognition and Behavior through Modulation of cAMP/Protein Kinase A Signaling Dalva M, Jayachandran R, Liu X, BoseDasgupta S, Müller P, Zhang C, Moshous D, Studer V, Schneider J, Genoud C, Fossoud C, Gambino F, Khelfaoui M, Müller C, Bartholdi D, Rossez H, Stiess M, Houbaert X, Jaussi R, Frey D, Kammerer Richard A, Deupi X, de Villartay J, Lüthi A, Humeau Y, Pieters J
    PLOS BIOLOGY 12, e1001820 (2014).
    DOI: 10.1371/journal.pbio.1001820
  • Crystallization Scale Preparation of a Stable GPCR Signaling Complex between Constitutively Active Rhodopsin and G-Protein Garriga P, Maeda S, Sun D, Singhal A, Foggetta M, Schmid G, Standfuss J, Hennig M, Dawson Roger JP, Veprintsev Dmitry B, Schertler Gebhard FX
    PLOS ONE 9, e98714 (2014).
    DOI: 10.1371/journal.pone.0098714
  • Cyclic Peptides as Inhibitors of Amyloid Fibrillation Luo J, Abrahams J
    CHEMISTRY - A EUROPEAN JOURNAL 20, 2410 (2014).
    DOI: 10.1002/chem.201304253
  • Endogenous Polyamines Reduce the Toxicity of Soluble A? Peptide Aggregates Associated with Alzheimer?s Disease Luo J, Mohammed I, Wärmländer Sebastian KTS, Hiruma Y, Gräslund A, Abrahams J
    BIOMACROMOLECULES 15, 1985 (2014).
    DOI: 10.1021/bm401874j
  • Femtosecond X-ray diffraction from two-dimensional protein crystals Frank Matthias, Carlson David B, Hunter Mark S, Williams Garth J, Messerschmidt Marc, Zatsepin Nadia A, Barty Anton, Benner W Henry, Chu Kaiqin, Graf Alexander T, Hau-Riege Stefan P, Kirian Richard A, Padeste Celestino, Pardini Tommaso, Pedrini Bill, Segelke Brent, Seibert M Marvin, Spence John C H, Tsai ChingJu, Lane Stephen M, Li XiaoDan, Schertler Gebhard, Boutet Sebastien, Coleman Matthew, Evans James E
    IUCRJ 1, 95-100 (2014).
    DOI: 10.1107/S2052252514001444
  • Functional and structural characterization of the kinase insert and the carboxy terminal domain in VEGF receptor 2 activation Manni Sandro, Kisko Kaisa, Schleier Thomas, Missimer Jack, Ballmer-Hofer Kurt
    FASEB JOURNAL 28, 4914-4923 (2014).
    DOI: 10.1096/fj.14-256206
  • Functional map of arrestin-1 at single amino acid resolution Ostermaier Martin K, Peterhans Christian, Jaussi Rolf, Deupi Xavier, Standfuss Joerg
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111, 1825-1830 (2014).
    DOI: 10.1073/pnas.1319402111
  • How Periplasmic Thioredoxin TlpA Reduces Bacterial Copper Chaperone ScoI and Cytochrome Oxidase Subunit II (CoxB) Prior to Metallation Abicht Helge K, Schaerer Martin A, Quade Nick, Ledermann Raphael, Mohorko Elisabeth, Capitani Guido, Hennecke Hauke, Glockshuber Rudi
    JOURNAL OF BIOLOGICAL CHEMISTRY 289, (2014).
    DOI: 10.1074/jbc.M114.607127
  • Hsp90-Tau Complex Reveals Molecular Basis for Specificity in Chaperone Action Karagöz G Elif, Duarte Afonso MS, Akoury E, Ippel H, Biernat J, Morán Luengo T, Radli M, Didenko T, Nordhues Bryce A, Veprintsev Dmitry B, Dickey Chad A, Mandelkow E, Zweckstetter M, Boelens R, Madl T, Rüdiger Stefan GD
    CELL 156, 963 (2014).
    DOI: 10.1016/j.cell.2014.01.037
  • Influence of Fluorination and Molecular Weight on the Morphology and Performance of PTB7:PC71BM Solar Cells He X, Mukherjee S, Watkins S, Chen M, Qin T, Thomsen L, Ade H, Mcneill C
    JOURNAL OF PHYSICAL CHEMISTRY C 118, 9918 (2014).
    DOI: 10.1021/jp501222w
  • Localizing Chemical Groups while Imaging Single Native Proteins by High-Resolution Atomic Force Microscopy Pfreundschuh Moritz, Alsteens David, Hilbert Manuel, Steinmetz Michel O, Mueller Daniel J
    NANO LETTERS 14, 2957-2964 (2014).
    DOI: 10.1021/nl5012905
  • Magnetically Enhanced Bicelles Delivering Switchable Anisotropy in Optical Gels Liebi M, Kuster S, Kohlbrecher J, Ishikawa T, Fischer P, Walde P, Windhab EJ
    ACS APPLIED MATERIALS & INTERFACES 6, 1100-1105 (2014).
    DOI: 10.1021/am4046469
  • Molecular mechanism of phosphorylation-dependent arrestin activation Ostermaier M, Schertler G, Standfuss J
    CURRENT OPINION IN STRUCTURAL BIOLOGY 29, 143 (2014).
    DOI: 10.1016/j.sbi.2014.07.006
  • NRP1 Presented in trans to the Endothelium Arrests VEGFR2 Endocytosis, Preventing Angiogenic Signaling and Tumor Initiation Koch S, van Meeteren Laurens A, Morin E, Testini C, Weström S, Björkelund H, Le Jan S, Adler J, Berger P, Claesson-Welsh L
    DEVELOPMENTAL CELL 28, 633 (2014).
    DOI: 10.1016/j.devcel.2014.02.010
  • Non-chaperone Proteins Can Inhibit Aggregation and Cytotoxicity of Alzheimer Amyloid ? Peptide Luo J, Wärmländer Sebastian KTS, Gräslund A, Abrahams J
    JOURNAL OF BIOLOGICAL CHEMISTRY 289, 27766 (2014).
    DOI: 10.1074/jbc.M114.574947
  • Preparation of Primary Neurons for Visualizing Neurites in a Frozen-hydrated State Using Cryo-Electron Tomography Shahmoradian SH, Galiano Mauricio R, Wu C, Chen S, Rasband Matthew N, Mobley William C, Chiu W
    Journal of Visualized Experiments -, - (2014).
    DOI: 10.3791/50783
  • Protein tagging reveals new insights into signaling in flagella Ishikawa T
    The Journal of Cell Biology 204, 631 (2014).
    DOI: 10.1083/jcb.201401142
  • Reconstitution of a hierarchical +TIP interaction network controlling microtubule end tracking of dynein Duellberg C, Trokter M, Jha R, Sen I, Steinmetz Michel O, Surrey T
    NATURE CELL BIOLOGY 16, 804 (2014).
    DOI: 10.1038/ncb2999
  • Reconstitution of a hierarchical plus TIP interaction network controlling microtubule end tracking of dynein Duellberg Christian, Trokter Martina, Jha Rupam, Sen Indrani, Steinmetz Michel O, Surrey Thomas
    NATURE CELL BIOLOGY 16, 804-U314 (2014).
    DOI: 10.1038/ncb2999
  • Regulation of alternative VEGF-A mRNA splicing is a therapeutic target for analgesia Hulse R P, Beazley-Long N, Hua J, Kennedy H, Prager J, Bevan H, Qiu Y, Fernandes E S, Gammons M V, Ballmer-Hofer K, de Groot A C Gittenberger, Churchill A J, Harper S J, Brain S D, Bates D O, Donaldson L F
    NEUROBIOLOGY OF DISEASE 71, 245-259 (2014).
    DOI: 10.1016/j.nbd.2014.08.012
  • Segmentation and quantification of subcellular structures in fluorescence microscopy images using Squassh Rizk A, Paul G, Incardona P, Bugarski M, Mansouri M, Niemann A, Ziegler U, Berger P, Sbalzarini I
    NATURE PROTOCOLS 9, 586 (2014).
    DOI: 10.1038/nprot.2014.037
  • Strategies for multigene expression in eukaryotic cells Mansouri M, Berger P
    PLASMID 75, 12 (2014).
    DOI: 10.1016/j.plasmid.2014.07.001
  • Structural Basis of Microtubule Stabilization by Laulimalide and Peloruside A Prota Andrea E, Bargsten Katja, Northcote Peter T, Marsh May, Altmann Karl-Heinz, Miller John H, Fernando Diaz Jose, Steinmetz Michel O
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 53, 1621-1625 (2014).
    DOI: 10.1002/anie.201307749
  • Structural and Functional Characterization of Alternative Transmembrane Domain Conformations in VEGF Receptor 2 Activation Manni Sandro, Mineev Konstantin S, Usmanova Dinara, Lyukmanova Ekaterina N, Shulepko Mikhail A, Kirpichnikov Mikhail P, Winter Jonas, Matkovic Milos, Deupi Xavier, Arseniev Alexander S, Ballmer-Hofer Kurt
    STRUCTURE 22, 1077-1089 (2014).
    DOI: 10.1016/j.str.2014.05.010
  • Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A Benoit Roger M, Frey Daniel, Hilbert Manuel, Kevenaar Josta T, Wieser Mara M, Stirnimann Christian U, McMillan David, Ceska Tom, Lebon Florence, Jaussi Rolf, Steinmetz Michel O, Schertler Gebhard F X, Hoogenraad Casper C, Capitani Guido, Kammerer Richard A
    NATURE 505, 108-+ (2014).
    DOI: 10.1038/nature12732
  • Structural basis for-10 promoter element melting by environmentally induced sigma factors Campagne Sebastien, Marsh May E, Capitani Guido, Vorholt Julia A, Allain Frederic H-T
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 21, 269-276 (2014).
    DOI: 10.1038/nsmb.2777
  • Structure of AMP-PNP-bound BtuCD and mechanism of ATP-powered vitamin B12 transport by BtuCD-F Korkhov Vladimir M, Mireku Samantha A, Veprintsev Dmitry B, Locher Kaspar P
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 21, 1097-1099 (2014).
    DOI: 10.1038/nsmb.2918
  • Structure of dimeric axonemal dynein in cilia suggests an alternative mechanism of force generation Ueno H, Bui K, Ishikawa T, Imai Y, Yamaguchi T, Ishikawa T
    Cytoskeleton 71, 412 (2014).
    DOI: 10.1002/cm.21180
  • Structure, Activity, and Stability of Atomically Dispersed Rh in Methane Steam Reforming Duarte RB, Krumeich F, van Bokhoven JA
    ACS CATALYSIS 4, 1279 (2014).
    DOI: 10.1021/cs400979q
  • The A- peptide forms non-amyloid fibrils in the presence of carbon nanotubes Luo J, Waermlaender Sebastian KTS, Yu C, Muhammad K, Graeslund A, Abrahams JP
    NANOSCALE 6, 6720 (2014).
    DOI: 10.1039/c4nr00291a
  • The Novel Microtubule-Destabilizing Drug BAL27862 Binds to the Colchicine Site of Tubulin with Distinct Effects on Microtubule Organization Prota Andrea E, Danel Franck, Bachmann Felix, Bargsten Katja, Buey Ruben M, Pohlmann Jens, Reinelt Stefan, Lane Heidi, Steinmetz Michel O
    JOURNAL OF MOLECULAR BIOLOGY 426, 1848-1860 (2014).
    DOI: 10.1016/j.jmb.2014.02.005
  • The hairpin conformation of the amyloid ? peptide is an important structural motif along the aggregation pathway Abelein A, Abrahams J, Danielsson J, Gräslund A, Jarvet J, Luo J, Tiiman A, Wärmländer Sebastian KTS
    JBIC JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 19, 623 (2014).
    DOI: 10.1007/s00775-014-1131-8
  • Transient Mechanistic Studies of Methane Steam Reforming over Ceria-Promoted Rh/Al2O3 Catalysts Duarte RB, Olea M, Iro E, Sasaki T, Itako K, van Bokhoven JA
    CHEMCATCHEM 6, 2898 (2014).
    DOI: 10.1002/cctc.201402388
  • Transport Pathway in Cu+ P-Type ATPases Andersson Magnus, Mattle Daniel, Sitsel Oleg, Nielsen Anna Marie, Lindahl Erik, White Stephen H, Nissen Poul, Gourdon Pontus
    BIOPHYSICAL JOURNAL 106, 427A-427A (2014).
    DOI: 10.1016/j.bpj.2013.11.2406

2013

  • (4R)- and (4S)-Fluoroproline in the Conserved cis-Prolyl Peptide Bond of the Thioredoxin Fold: Tertiary Structure Context Dictates Ring Puckering Rubini Marina, Schaerer Martin A, Capitani Guido, Glockshuber Rudi
    CHEMBIOCHEM 14, 1053-1057 (2013).
    DOI: 10.1002/cbic.201300178
  • A Medipix quantum area detector allows rotation electron diffraction data collection from submicrometre three-dimensional protein crystals Nederlof I, van Genderen E, Li Y, Abrahams J
    ACTA CRYSTALLOGRAPHICA SECTION D - BIOLOGICAL CRYSTALLOGRAPHY 69, 1223 (2013).
    DOI: 10.1107/S0907444913009700
  • AAscan, PCRdesign and MutantChecker: A Suite of Programs for Primer Design and Sequence Analysis for High-Throughput Scanning Mutagenesis Sun D, Ostermaier Martin K, Heydenreich Franziska M, Mayer D, Jaussi R, Standfuss J, Veprintsev Dmitry B
    PLOS ONE 8, e78878 (2013).
    DOI: 10.1371/journal.pone.0078878
  • An efficient nanolitre-volume multi-channel device for highly viscous materials used in membrane protein crystallization Luo J, Zwier R, Abrahams J
    JOURNAL OF APPLIED CRYSTALLOGRAPHY 46, 829 (2013).
    DOI: 10.1107/S0021889813006742
  • Anomalous signal from S atoms in protein crystallographic data from an X-ray free-electron laser Barends Thomas R M, Foucar Lutz, Shoeman Robert L, Bari Sadia, Epp Sascha W, Hartmann Robert, Hauser Gunter, Huth Martin, Kieser Christian, Lomb Lukas, Motomura Koji, Nagaya Kiyonobu, Schmidt Carlo, Strecker Rafael, Anielski Denis, Boll Rebecca, Erk Benjamin, Fukuzawa Hironobu, Hartmann Elisabeth, Hatsui Takaki, Holl Peter, Inubushi Yuichi, Ishikawa Tetsuya, Kassemeyer Stephan, Kaiser Christian, Koeck Frank, Kunishima Naoki, Kurka Moritz, Rolles Daniel, Rudek Benedikt, Rudenko Artem, Sato Takahiro, Schroeter Claus-Dieter, Soltau Heike, Strueder Lothar, Tanaka Tomoyuki, Togashi Tadashi, Tono Kensuke, Ullrich Joachim, Yase Satoshi, Wada Shin-ichi, Yao Makoto, Yabashi Makina, Ueda Kiyoshi, Schlichting Ilme
    ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 69, 838-842 (2013).
    DOI: 10.1107/S0907444913002448
  • Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry Hilbert M, Erat MC, Hachet V, Guichard P, Blank ID, Fluckiger I, Slater L, Lowe ED, Hatzopoulos GN, Steinmetz MO, Gonczy P, Vakonakis I
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110, 11373 (2013).
    DOI: 10.1073/pnas.1302721110
  • Capture of unstable protein complex on the streptavidin-coated single-walled carbon nanotubes Liu Z, Voskamp P, Zhang Y, Chu F, Abrahams J
    JOURNAL OF NANOPARTICLE RESEARCH 15, (2013).
    DOI: 10.1007/s11051-013-1582-9
  • Cellular Polyamines Promote Amyloid-Beta (A?) Peptide Fibrillation and Modulate the Aggregation Pathways Luo J, Yu C, Yu H, Borstnar R, Kamerlin Shina CL, Gräslund A, Abrahams J, Wärmländer Sebastian KTS
    ACS Chemical Neuroscience 4, 454 (2013).
    DOI: 10.1021/cn300170x
  • Cholesterol-Diethylenetriaminepentaacetate Complexed with Thulium Ions Integrated into Bicelles To Increase Their Magnetic Alignability Liebi M, Kuster S, Kohlbrecher J, Ishikawa T, Fischer P, Walde P, Windhab Erich J
    JOURNAL OF PHYSICAL CHEMISTRY B 117, 14743 (2013).
    DOI: 10.1021/jp406599c
  • Constitutively active rhodopsin mutants causing night blindness are effectively phosphorylated by GRKs but differ in arrestin-1 binding Vishnivetskiy SergeyA, Ostermaier Martin K, Singhal A, Panneels V, Homan Kristoff T, Glukhova A, Sligar Stephen G, Tesmer John JG, Schertler Gebhard FX, Standfuss J, Gurevich Vsevolod V
    CELLULAR SIGNALLING 25, 2155 (2013).
    DOI: 10.1016/j.cellsig.2013.07.009
  • Coordination of VEGF receptor trafficking and signaling by coreceptors Nakayama M, Berger P
    EXPERIMENTAL CELL RESEARCH 319, 1340 (2013).
    DOI: 10.1016/j.yexcr.2013.03.008
  • Cryo-scanning x-ray diffraction microscopy of frozen-hydrated yeast Lima E, Diaz A, Guizar-Sicairos M, Gorelick S, Pernot P, Schleier T, Menzel A
    JOURNAL OF MICROSCOPY 249, 1-7 (2013).
    DOI: 10.1111/j.1365-2818.2012.03682.x
  • End Binding Proteins Are Obligatory Dimers Wiche G, Sen I, Veprintsev D, Akhmanova A, Steinmetz Michel O
    PLOS ONE 8, e74448 (2013).
    DOI: 10.1371/journal.pone.0074448
  • End-binding proteins sensitize microtubules to the action of microtubule-targeting agents Mohan Renu, Katrukha Eugene A, Doodhi Harinath, Smal Ihor, Meijering Erik, Kapitein Lukas C, Steinmetz Michel O, Akhmanova Anna
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110, 8900-8905 (2013).
    DOI: 10.1073/pnas.1300395110
  • Human lysozyme inhibits the in vitro aggregation of A? peptides, which in vivo are associated with Alzheimer's disease Luo J, Wärmländer Sebastian KTS, Gräslund A, Abrahams J
    CHEMICAL COMMUNICATIONS 49, 6507 (2013).
    DOI: 10.1039/c3cc42325e
  • Imaging protein three-dimensional nanocrystals with cryo-EM Nederlof I, Li Y, van Heel M, Abrahams J
    ACTA CRYSTALLOGRAPHICA SECTION D - BIOLOGICAL CRYSTALLOGRAPHY 69, 852 (2013).
    DOI: 10.1107/S0907444913002734
  • Insights into congenital stationary night blindness based on the structure of G90D rhodopsin Singhal Ankita, Ostermaier Martin K, Vishnivetskiy Sergey A, Panneels Valerie, Homan Kristoff T, Tesmer John J G, Veprintsev Dmitry, Deupi Xavier, Gurevich Vsevolod V, Schertler Gebhard F X, Standfuss Joerg
    EMBO REPORTS 14, 520-526 (2013).
    DOI: 10.1038/embor.2013.44
  • Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents Prota Andrea E, Bargsten Katja, Zurwerra Didier, Field Jessica J, Fernando Diaz Jose, Altmann Karl-Heinz, Steinmetz Michel O
    SCIENCE 339, 587-590 (2013).
    DOI: 10.1126/science.1230582
  • Molecular signatures of G-protein-coupled receptors Venkatakrishnan A J, Deupi Xavier, Lebon Guillaume, Tate Christopher G, Schertler Gebhard F, Babu M Madan
    NATURE 494, 185-194 (2013).
    DOI: 10.1038/nature11896
  • Native Architecture of the Centriole Proximal Region Reveals Features Underlying Its 9-Fold Radial Symmetry Guichard P, Hachet V, Majubu N, Neves A, Demurtas D, Olieric N, Fluckiger I, Yamada A, Kihara K, Nishida Y, Moriya S, Steinmetz Michel O, Hongoh Y, Gönczy P
    CURRENT BIOLOGY 23, 1620 (2013).
    DOI: 10.1016/j.cub.2013.06.061
  • Quaternary Dynamics of the SecA Motor Drive Translocase Catalysis Gouridis G, Karamanou S, Sardis MF, Schaerer MA, Capitani G, Economou A
    MOLECULAR CELL 52, 655-666 (2013).
    DOI: 10.1016/j.molcel.2013.10.036
  • Relation between sequence and structure in membrane proteins Olivella Mireia, Gonzalez Angel, Pardo Leonardo, Deupi Xavier
    BIOINFORMATICS 29, 1589-1592 (2013).
    DOI: 10.1093/bioinformatics/btt249
  • Structural Basis for Universal Corrinoid Recognition by the Cobalamin Transport Protein Haptocorrin Furger E, Frei DC, Schibli R, Fischer E, Prota AE
    JOURNAL OF BIOLOGICAL CHEMISTRY 288, 25466 (2013).
  • Structural Basis for the Oligomerization-State Switch from a Dimer to a Trimer of an Engineered Cortexillin-1 Coiled-Coil Variant Bjelic Sasa, Wieser Mara, Frey Daniel, Stirnimann Christian U, Chance Mark R, Jaussi Rolf, Steinmetz Michel O, Kammerer Richard A
    PLOS ONE 8, e63370 (2013).
    DOI: 10.1371/journal.pone.0063370
  • Structural and mechanistic insights into VEGF receptor 3 ligand binding and activation Leppanen Veli-Matti, Tvorogov Denis, Kisko Kaisa, Prota Andrea E, Jeltsch Michael, Anisimov Andrey, Markovic-Mueller Sandra, Stuttfeld Edward, Goldie Kenneth N, Ballmer-Hofer Kurt, Alitalo Kari
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110, 12960-12965 (2013).
    DOI: 10.1073/pnas.1301415110
  • Structural basis of tubulin tyrosination by tubulin tyrosine ligase Prota Andrea E, Magiera Maria M, Kuijpers Marijn, Bargsten Katja, Frey Daniel, Wieser Mara, Jaussi Rolf, Hoogenraad Casper C, Kammerer Richard A, Janke Carsten, Steinmetz Michel O
    JOURNAL OF CELL BIOLOGY 200, 259-270 (2013).
    DOI: 10.1083/jcb.201211017
  • Structure of beta-Adrenergic Receptors Brueckner Florian, Piscitelli Chayne L, Tsai Ching-Ju, Standfuss Joerg, Deupi Xavier, Schertler Gebhard F X
    G PROTEIN COUPLED RECEPTORS: STRUCTURE 520, 117-151 (2013).
    DOI: 10.1016/B978-0-12-391861-1.00006-X
  • TRiC?s tricks inhibit huntingtin aggregation Shahmoradian S, Galaz-Montoya J, Schmid M, Cong Y, Ma B, Spiess C, Frydman J, Ludtke S, Chiu W
    ELIFE 2, - (2013).
    DOI: 10.7554/eLife.00710
  • Two Alternative Conformations of a Voltage-Gated Sodium Channel Tsai C, Tani K, Irie K, Hiroaki Y, Shimomura T, McMillan Duncan G, Cook Gregory M, Schertler Gebhard FX, Fujiyoshi Y, Li X
    JOURNAL OF MOLECULAR BIOLOGY 425, 4074 (2013).
    DOI: 10.1016/j.jmb.2013.06.036
  • Visualizing the localization of transfection complexes during graphene nanoparticle-based transfection Bruggencate F, Laroche F, Zhang Y, Song G, Yin S, Abrahams J, Liu Z
    JOURNAL OF MATERIALS CHEMISTRY B 1, 6353 (2013).
    DOI: 10.1039/C3TB21349H

2012

  • A Proteome-wide Screen for Mammalian SxIP Motif-Containing Microtubule Plus-End Tracking Proteins Jiang K, Toedt G, Montenegro Gouveia S, Davey Norman E, Hua S, van der Vaart B, Grigoriev I, Larsen J, Pedersen Lotte B, Bezstarosti K, Lince-Faria M, Demmers J, Steinmetz Michel O, Gibson Toby J, Akhmanova A
    CURRENT BIOLOGY 22, 1800 (2012).
    DOI: 10.1016/j.cub.2012.07.047
  • An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid de la Roche Marc, Rutherford Trevor J, Gupta Deepti, Veprintsev Dmitry B, Saxty Barbara, Freund Stefan M, Bienz Mariann
    NATURE COMMUNICATIONS 3, 680 (2012).
    DOI: 10.1038/ncomms1680
  • Bin2 Is a Membrane Sculpting N-BAR Protein That Influences Leucocyte Podosomes, Motility and Phagocytosis Soldati T, Sánchez-Barrena M, Vallis Y, Clatworthy Menna R, Doherty Gary J, Veprintsev Dmitry B, Evans Philip R, McMahon Harvey T
    PLOS ONE 7, e52401 (2012).
    DOI: 10.1371/journal.pone.0052401
  • Characterisation of a counting imaging detector for electron detection in the energy range 10?20keV Moldovan G, Sikharulidze I, Matheson J, Derbyshire G, Kirkland AI, Abrahams JP
    Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Dectectors and Associated Equipment 681, 21 (2012).
    DOI: 10.1016/j.nima.2012.03.033
  • Comparative structural analysis of eukaryotic flagella and cilia from Chlamydomonas, Tetrahymena, and sea urchins Pigino G, Maheshwari A, Bui K, Shingyoji C, Kamimura S, Ishikawa T
    JOURNAL OF STRUCTURAL BIOLOGY 178, 199 (2012).
    DOI: 10.1016/j.jsb.2012.02.012
  • Conformation Effects of CpG Methylation on Single-Stranded DNA Oligonucleotides: Analysis of the Opioid Peptide Dynorphin-Coding Sequences Taqi M, Wärmländer Sebastian KTS, Yamskova O, Madani F, Bazov I, Luo J, Zubarev R, Verbeek D, Gräslund A, Bakalkin G
    PLOS ONE 7, e39605 (2012).
    DOI: 10.1371/journal.pone.0039605
  • Conserved activation pathways in G-protein-coupled receptors Deupi X, Standfuss J, Schertler G
    BIOCHEMICAL SOCIETY TRANSACTIONS 40, 383-388 (2012).
    DOI: 10.1042/BST20120001
  • Cooperative Stabilization of Microtubule Dynamics by EB1 and CLIP-170 Involves Displacement of Stably Bound P i at Microtubule Ends Lopus M, Manatschal C, Buey Ruben M, Bjelic S, Miller Herbert P, Steinmetz Michel O, Wilson L
    BIOCHEMISTRY 51, 3021 (2012).
    DOI: 10.1021/bi300038t
  • Functionalized Low-Density Lipoprotein Nanoparticles for in Vivo Enhancement of Atherosclerosis on Magnetic Resonance Images Lowell Andrew N, Qiao H, Liu T, Ishikawa T, Zhang H, Oriana S, Wang M, Ricciotti E, FitzGerald Garret A, Zhou R, Yamakoshi Y
    BIOCONJUGATE CHEMISTRY 23, 2313 (2012).
    DOI: 10.1021/bc300561e
  • Influence of 63Ser Phosphorylation and Dephosphorylation on the Structure of the Stathmin Helical Nucleation Sequence: A Molecular Dynamics Study Missimer John H, Steinmetz Michel O, van Gunsteren Wilfred F, Dolenc Jozica
    BIOCHEMISTRY 51, 8455-8463 (2012).
    DOI: 10.1021/bi300885y
  • Interaction of mammalian end binding proteins with CAP-Gly domains of CLIP-170 and p150(glued) Bjelic S, De Groot CO, Scharer MA, Jaussi R, Bargsten K, Salzmann M, Frey D, Capitani G, Kammerer RA, Steinmetz MO
    JOURNAL OF STRUCTURAL BIOLOGY 177, 160 (2012).
    DOI: 10.1016/j.jsb.2011.11.010
  • Lithocholic acid is an endogenous inhibitor of MDM4 and MDM2 Vogel SM, Bauer MR, Joerger AC, Wilcken R, Brandt T, Veprintsev DB, Rutherford TJ, Fersht AR, Boeckler FM
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109, 16906 (2012).
    DOI: 10.1073/pnas.1215060109
  • Molecular Basis for Modulation of the p53 Target Selectivity by KLF4 Mayer C, Brandt T, Townsley Fiona M, Teufel Daniel P, Freund Stefan MV, Veprintsev Dmitry B
    PLOS ONE 7, e48252 (2012).
    DOI: 10.1371/journal.pone.0048252
  • Mouse respiratory cilia with the asymmetric axonemal structure on sparsely distributed ciliary cells can generate overall directional flow Ueno H, Ishikawa T, Bui K, Gonda K, Ishikawa T, Yamaguchi T
    Nanomedicine: Nanotechnology, Biology and Medicine 8, 1081 (2012).
    DOI: 10.1016/j.nano.2012.01.004
  • Polarity and asymmetry in the arrangement of dynein and related structures in the Chlamydomonas axoneme Bui K, Yagi T, Yamamoto R, Kamiya R, Ishikawa T
    The Journal of Cell Biology 198, 913 (2012).
    DOI: 10.1083/jcb.201201120
  • Practical Aspects in Expression and Purification of Membrane Proteins for Structural Analysis Vinothkumar Kutti R, Edwards Patricia C, Standfuss J
    Methods in Molecular Biology 955, 17 (2012).
    DOI: 10.1007/978-1-62703-176-9_2
  • Probing the Structure and Dynamics of Proteins by Combining Molecular Dynamics Simulations and Experimental NMR Data Allison Jane R, Hertig S, Missimer John H, Smith Lorna J, Steinmetz Michel O, Dolenc J
    JOURNAL OF CHEMICAL THEORY AND COMPUTATION 8, 3430 (2012).
    DOI: 10.1021/ct300393b
  • Protein interface classification by evolutionary analysis Duarte JM, Srebniak A, Scharer MA, Capitani G
    BMC BIOINFORMATICS 13, 334 (2012).
    DOI: 10.1186/1471-2105-13-334
  • Quality control of disulfide bond formation in pilus subunits by the chaperone FimC Crespo MD, Puorger C, Scharer MA, Eidam O, Grutter MG, Capitani G, Glockshuber R
    NATURE CHEMICAL BIOLOGY 8, 707-713 (2012).
    DOI: 10.1038/NCHEMBIO.1019
  • Revisiting the Supramolecular Organization of Photosystem II in Chlamydomonas reinhardtii Tokutsu R, Kato N, Bui KH, Ishikawa T, Minagawa J
    JOURNAL OF BIOLOGICAL CHEMISTRY 287, 31574 (2012).
    DOI: 10.1074/jbc.M111.331991
  • Sequence Determinants of a Microtubule Tip Localization Signal (MtLS) Buey RM, Sen I, Kortt O, Mohan R, Gfeller D, Veprintsev D, Kretzschmar I, Scheuermann J, Neri D, Zoete V, Michielin O, de Pereda JM, Akhmanova A, Volkmer R, Steinmetz MO
    JOURNAL OF BIOLOGICAL CHEMISTRY 287, 28227 (2012).
    DOI: 10.1074/jbc.M112.373928
  • Single-Walled Carbon Nanotubes as Scaffolds to Concentrate DNA for the Study of DNA-Protein Interactions Liu Z, Galli F, Waterreus W, Meulenbroek E, Koning Roman I, Lamers Gerda EM, Olsthoorn René CL, Pannu N, Oosterkamp TjerkH, Koster Abraham J, Dame Remus T, Abrahams J
    CHEMPHYSCHEM 13, 1569 (2012).
    DOI: 10.1002/cphc.201100896
  • Specific Recognition of p53 Tetramers by Peptides Derived from p53 Interacting Proteins Jones D, Gabizon R, Brandt T, Sukenik S, Lahav N, Lebendiker M, Shalev Deborah E, Veprintsev D, Friedler A
    PLOS ONE 7, e38060 (2012).
    DOI: 10.1371/journal.pone.0038060
  • Stability of p53 Homologs Jones DDafydd, Brandt T, Kaar Joel L, Fersht Alan R, Veprintsev Dmitry B
    PLOS ONE 7, e47889 (2012).
    DOI: 10.1371/journal.pone.0047889
  • Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II Deupi X, Edwards P, Singhal A, Nickle B, Oprian D, Schertler G, Standfuss J
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109, 119 (2012).
    DOI: 10.1073/pnas.1114089108
  • Structural insights into biased G protein-coupled receptor signaling revealed by fluorescence spectroscopy Rahmeh R, Damian M, Cottet M, Orcel H, Mendre C, Durroux T, Sharma KS, Durand G, Pucci B, Trinquet E, Zwier JM, Deupi X, Bron P, Baneres JL, Mouillac B, Granier S
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109, 6733-6738 (2012).
    DOI: 10.1073/pnas.1201093109
  • Structure of a post-translationally processed heterodimeric double-headed Kunitz-type serine protease inhibitor from potato Meulenbroek Elisabeth M, Thomassen Ellen AJ, Pouvreau L, Abrahams J, Gruppen H, Pannu Navraj S
    ACTA CRYSTALLOGRAPHICA SECTION D - BIOLOGICAL CRYSTALLOGRAPHY 68, 794 (2012).
    DOI: 10.1107/S090744491201222X
  • Supramolecular Non-Amyloid Intermediates in the Early Stages of ?-Synuclein Aggregation Fauerbach Jonathan A, Yushchenko Dmytro A, Shahmoradian Sarah H, Chiu W, Jovin Thomas M, Jares-Erijman Elizabeth A
    BIOPHYSICAL JOURNAL 102, 1127 (2012).
    DOI: 10.1016/j.bpj.2012.01.051
  • Thermodynamic and structural description of allosterically regulated VEGFR-2 dimerization Brozzo MS, Bjelic S, Kisko K, Schleier T, Leppanen VM, Alitalo K, Winkler FK, Ballmer-Hofer K
    BLOOD 119, 1781 (2012).
    DOI: 10.1182/blood-2011-11-390922
  • Tyrosine-dependent capture of CAP-Gly domain-containing proteins in complex mixture by EB1 C-terminal peptidic probes Calligaris D, Manatschal C, Marcellin M, Villard C, Monsarrat B, Burlet-Schiltz O, Steinmetz Michel O, Braguer D, Lafitte D, Verdier-Pinard P
    Journal of Proteomics 75, 3605 (2012).
    DOI: 10.1016/j.jprot.2012.04.006
  • Ultra-small graphene oxide functionalized with polyethylenimine (PEI) for very efficient gene delivery in cell and zebrafish embryos Zhou X, Laroche F, Lamers Gerda EM, Torraca V, Voskamp P, Lu T, Chu F, Spaink Herman P, Abrahams J, Liu Z
    Nano Research 5, 703 (2012).
    DOI: 10.1007/s12274-012-0254-x

2011

  • A Prokaryotic S1P Lyase Degrades Extracellular S1P In Vitro and In Vivo: Implication for Treating Hyperproliferative Disorders Ho P, Huwiler A, Bourquin F, Kotelevets N, Pastukhov O, Capitani G, Grütter Markus G, Zangemeister-Wittke U
    PLOS ONE 6, e22436 (2011).
    DOI: 10.1371/journal.pone.0022436
  • A Straightforward and Robust Method for Introducing Human Hair as a Nucleant into High Throughput Crystallization Trials Nederlof I, Hosseini R, Georgieva D, Luo J, Li D, Abrahams J
    CRYSTAL GROWTH & DESIGN 11, 1170 (2011).
    DOI: 10.1021/cg101374r
  • A direct way of redox sensing Benoit Roger M, Auer Manfred
    RNA BIOLOGY 8, 18-23 (2011).
    DOI: 10.4161/rna.8.1.13555
  • Acetylation of lysine 120 of p53 endows DNA-binding specificity at effective physiological salt concentration Arbely E, Natan E, Brandt T, Allen MD, Veprintsev DB, Robinson CV, Chin JW, Joerger AC, Fersht AR
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 108, 8251 (2011).
    DOI: 10.1073/pnas.1105028108
  • Advances in the CRANK software suite for automated crystal structure solution Waterreus WJ, Skubák P, Sikharulidze I, Abrahams JP, de Graaff RAG, Pannu NS
    Acta Crystallographica Section A Foundations of Crystallography 67, C659 (2011).
    DOI: 10.1107/S0108767311083346
  • CMView: Interactive contact map visualization and analysis Vehlow C, Stehr H, Winkelmann M, Duarte JM, Petzold L, Dinse J, Lappe M
    BIOINFORMATICS 27, 1573 (2011).
    DOI: 10.1093/bioinformatics/btr163
  • Cholesterol attenuates and prevents bilayer damage and breakdown in lipoperoxidized model membranes. A spin labeling EPR study Megli Francesco M, Conte E, Ishikawa T
    Biochimica et Biophysica Acta (BBA) - Biomembranes 1808, 2267 (2011).
    DOI: 10.1016/j.bbamem.2011.04.016
  • Cryoelectron tomography of radial spokes in cilia and flagella Pigino G, Bui K, Maheshwari A, Lupetti P, Diener D, Ishikawa T
    The Journal of Cell Biology 195, 673 (2011).
    DOI: 10.1083/jcb.201106125
  • Crystal structure of the GlnZ-DraG complex reveals a different form of P-II-target interaction Rajendran C, Gerhardt ECM, Bjelic S, Gasperina A, Scarduelli M, Pedrosa FO, Chubatsu LS, Merrick M, Souza EM, Winkler FK, Huergo LF, Li XD
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 108, 18972 (2011).
    DOI: 10.1073/pnas.1108038108
  • EDIFF : a program for automated unit-cell determination and indexing of electron diffraction data Jiang L, Georgieva D, Abrahams J
    JOURNAL OF APPLIED CRYSTALLOGRAPHY 44, 1132 (2011).
    DOI: 10.1107/S0021889811030731
  • ELM--the database of eukaryotic linear motifs Dinkel H, Michael S, Weatheritt RJ, Davey NE, Van Roey K, Altenberg B, Toedt G, Uyar B, Seiler M, Budd A, Jodicke L, Dammert MA, Schroeter C, Hammer M, Schmidt T, Jehl P, McGuigan C, Dymecka M, Chica C, Luck K, Via A, Chatr-aryamontri A, Haslam N, Grebnev G, Edwards RJ, Steinmetz MO, Meiselbach H, Diella F, Gibson TJ
    NUCLEIC ACIDS RESEARCH 40, D242 (2011).
    DOI: 10.1093/nar/gkr1064
  • Electron diffraction of submicron three-dimensional protein crystals Nederlof I, Georgieva D, Abrahams JP
    Acta Crystallographica Section A Foundations of Crystallography 67, C228 (2011).
    DOI: 10.1107/S010876731109430X
  • Evaluation of Medipix2 detector for recording electron diffraction data in low dose conditions Georgieva D, Jansen J, Sikharulidze I, Jiang L, Zandbergen H, Abrahams J
    JOURNAL OF INSTRUMENTATION 6, C01033 (2011).
    DOI: 10.1088/1748-0221/6/01/C01033
  • IMPROVED IMAGING IN LOW ENERGY ELECTRON MICROSCOPY AND PHOTO EMISSION ELECTRON MICROSCOPY USING MEDIPIX2 PIXEL DETECTOR SIKHARULIDZE I, van GASTEL R, SCHRAMM S, ABRAHAMS JP, POELSEMA B, TROM RM, van der MOLEN SJ
    Astroparticle, Particle and Space Physics, Detectors and Medical Physics Applications , (2011).
    DOI: 10.1142/9789814307529_0023
  • Image Processing and Lattice Determination for Three-Dimensional Nanocrystals Jiang L, Georgieva D, Nederlof I, Liu Z, Abrahams J
    MICROSCOPY AND MICROANALYSIS 17, 879 (2011).
    DOI: 10.1017/S1431927611012244
  • Insights into EB1 structure and the role of its C-terminal domain for discriminating microtubule tips from the lattice Buey RM, Mohan R, Leslie K, Walzthoeni T, Missimer JH, Menzel A, Bjelic S, Bargsten K, Grigoriev I, Smal I, Meijering E, Aebersold R, Akhmanova A, Steinmetz MO
    MOLECULAR BIOLOGY OF THE CELL 22, 2912 (2011).
    DOI: 10.1091/mbc.E11-01-0017
  • Integration of multiple expression cassettes into mammalian genomes in a single step Kriz A, Schmid K, Ballmer K, Berger P
    Protocol Exchange , (2011).
    DOI: 10.1038/protex.2011.249
  • Low energy electron microscopy imaging using Medipix2 detector Sikharulidze I, van Gastel R, Schramm S, Abrahams JP, Poelsema B, Tromp RM, van der Molen SJ
    Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Dectectors and Associated Equipment 633, S239 (2011).
    DOI: 10.1016/j.nima.2010.06.177
  • Low-resolution electron crystallography challenges in organic and inorganic crystals with transmission electron microscope (TEM) Nicolopoulos S, Rauch E, Georgieva D, Abrahams JP
    Acta Crystallographica Section A Foundations of Crystallography 67, C188 (2011).
    DOI: 10.1107/S0108767311095304
  • Microtubule End Binding: EBs Sense the Guanine Nucleotide State Akhmanova A, Steinmetz MO
    CURRENT BIOLOGY 21, R283 (2011).
    DOI: 10.1016/j.cub.2011.03.023
  • Neuropilin-1 promotes VEGFR-2 trafficking through Rab11 vesicles thereby specifying signal output Ballmer-Hofer K, Andersson AE, Ratcliffe LE, Berger P
    BLOOD 118, 816 (2011).
    DOI: 10.1182/blood-2011-01-328773
  • Preparation of an Activated Rhodopsin/Transducin Complex Using a Constitutively Active Mutant of Rhodopsin Xie G, D?Antona Aaron M, Edwards Patricia C, Fransen M, Standfuss J, Schertler Gebhard FX, Oprian Daniel D
    BIOCHEMISTRY 50, 10399 (2011).
    DOI: 10.1021/bi201126r
  • Quaternary Structure of the Oxaloacetate Decarboxylase Membrane Complex and Mechanistic Relationships to Pyruvate Carboxylases Balsera M, Buey RM, Li XD
    JOURNAL OF BIOLOGICAL CHEMISTRY 286, 9457 (2011).
    DOI: 10.1074/jbc.M110.197442
  • RNA polymerase I?specific subunits promote polymerase clustering to enhance the rRNA gene transcription cycle Albert B, Léger-Silvestre I, Normand C, Ostermaier M, Pérez-Fernández J, Panov Kostya I, Zomerdijk Joost CBM, Schultz P, Gadal O
    The Journal of Cell Biology 192, 277 (2011).
    DOI: 10.1083/jcb.201006040
  • Recent advances in the CRANK software suite for experimental phasing Pannu Navraj S, Waterreus W, Skubák P, Sikharulidze I, Abrahams J, de Graaff Rudolf AG
    ACTA CRYSTALLOGRAPHICA SECTION D - BIOLOGICAL CRYSTALLOGRAPHY 67, 331 (2011).
    DOI: 10.1107/S0907444910052224
  • SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase van der Vaart B, Manatschal C, Grigoriev I, Olieric V, Gouveia SM, Bjelic S, Demmers J, Vorobjev I, Hoogenraad CC, Steinmetz MO, Akhmanova A
    JOURNAL OF CELL BIOLOGY 193, 1083 (2011).
    DOI: 10.1083/jcb.201012179
  • Structural Basis of the 9-Fold Symmetry of Centrioles Kitagawa D, Vakonakis I, Olieric N, Hilbert M, Keller D, Olieric V, Bortfeld M, Erat MC, Fluckiger I, Gonczy P, Steinmetz MO
    CELL 144, 364 (2011).
    DOI: 10.1016/j.cell.2011.01.008
  • Structural analysis of vascular endothelial growth factor receptor-2/ligand complexes by small-angle X-ray solution scattering Kisko K, Brozzo MS, Missimer J, Schleier T, Menzel A, Leppanen VM, Alitalo K, Walzthoeni T, Aebersold R, Ballmer-Hofer K
    FASEB JOURNAL 25, 2980 (2011).
    DOI: 10.1096/fj.11-185397
  • Structural basis for reduced activity of 1-aminocyclopropane-1-carboxylate synthase affected by a mutation linked to andromonoecy Scharer MA, Eliot AC, Grutter MG, Capitani G
    FEBS LETTERS 585, 111 (2011).
    DOI: 10.1016/j.febslet.2010.11.013
  • Structural determinants of vascular endothelial growth factor-D receptor binding and specificity Leppanen VM, Jeltsch M, Anisimov A, Tvorogov D, Aho K, Kalkkinen N, Toivanen P, Yla-Herttuala S, Ballmer-Hofer K, Alitalo K
    BLOOD 117, 1507 (2011).
    DOI: 10.1182/blood-2010-08-301549
  • Structural insights into agonist-induced activation of G-protein-coupled receptors Deupi X, Standfuss J
    CURRENT OPINION IN STRUCTURAL BIOLOGY 21, 541 (2011).
    DOI: 10.1016/j.sbi.2011.06.002
  • Structures of SAS-6 Suggest Its Organization in Centrioles van Breugel M, Hirono M, Andreeva A, Yanagisawa Ha, Yamaguchi S, Nakazawa Y, Morgner N, Petrovich M, Ebong IO, Robinson CV, Johnson CM, Veprintsev D, Zuber B
    SCIENCE 331, 1196 (2011).
    DOI: 10.1126/science.1199325
  • Subunit-selective N-terminal domain associations organize the formation of AMPA receptor heteromers Rossmann M, Sukumaran M, Penn A, Veprintsev D, Babu M, Greger I
    The EMBO Journal 30, 959 (2011).
    DOI: 10.1038/emboj.2011.16
  • The CMT4B disease-causing proteins MTMR2 and MTMR13/SBF2 regulate AKT signalling Berger P, Tersar K, Ballmer-Hofer K, Suter U
    JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 15, 307 (2011).
    DOI: 10.1111/j.1582-4934.2009.00967.x
  • The DNA-Binding Domain of Human PARP-1 Interacts with DNA Single-Strand Breaks as a Monomer through Its Second Zinc Finger Eustermann S, Videler H, Yang J, Cole Paul T, Gruszka D, Veprintsev D, Neuhaus D
    JOURNAL OF MOLECULAR BIOLOGY 407, 149 (2011).
    DOI: 10.1016/j.jmb.2011.01.034
  • The structural basis for agonist and partial agonist action on a beta(1)-adrenergic receptor Warne T, Moukhametzianov R, Baker JG, Nehme R, Edwards PC, Leslie AGW, Schertler GFX, Tate CG
    NATURE 469, 241 (2011).
    DOI: 10.1038/nature09746
  • The structural basis of agonist-induced activation in constitutively active rhodopsin Standfuss J, Edwards PC, D'Antona A, Fransen M, Xie GF, Oprian DD, Schertler GFX
    NATURE 471, 656 (2011).
    DOI: 10.1038/nature09795
  • The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors Stehr H, Jang S, Duarte J, Wierling C, Lehrach H, Lappe M, Lange B
    Molecular Cancer 10, 54 (2011).
    DOI: 10.1186/1476-4598-10-54
  • Two distinct conformations of helix 6 observed in antagonist-bound structures of a beta(1)-adrenergic receptor Moukhametzianov R, Warne T, Edwards PC, Serrano-Vega MJ, Leslie AGW, Tate CG, Schertler GFX
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 108, 8228 (2011).
    DOI: 10.1073/pnas.1100185108

2010

  • A Graphene Oxide?Streptavidin Complex for Biorecognition - Towards Affinity Purification Liu Z, Jiang L, Galli F, Nederlof I, Olsthoorn René CL, Lamers Gerda EM, Oosterkamp TjerkH, Abrahams J
    ADVANCED FUNCTIONAL MATERIALS 20, 2857 (2010).
    DOI: 10.1002/adfm.201000761
  • A New P-II Protein Structure Identifies the 2-Oxoglutarate Binding Site Truan D, Huergo LF, Chubatsu LS, Merrick M, Li XD, Winkler FK
    JOURNAL OF MOLECULAR BIOLOGY 400, 531 (2010).
    DOI: 10.1016/j.jmb.2010.05.036
  • A novel approximation method of CTF amplitude correction for 3D single particle reconstruction Jiang L, Liu Z, Georgieva D, Kuil Maxim E, Abrahams J
    ULTRAMICROSCOPY 110, 350 (2010).
    DOI: 10.1016/j.ultramic.2010.01.011
  • A plasmid-based multigene expression system for mammalian cells Kriz A, Schmid K, Baumgartner N, Ziegler U, Berger I, Ballmer-Hofer K, Berger P
    NATURE COMMUNICATIONS 1, 120 (2010).
    DOI: 10.1038/ncomms1120
  • Automated seamless DNA co-transformation cloning with direct expression vectors applying positive or negative insert selection Olieric N, Kuchen M, Wagen S, Sauter M, Crone S, Edmondson S, Frey D, Ostermeier C, Steinmetz M, Jaussi R
    BMC BIOTECHNOLOGY 10, 56 (2010).
    DOI: 10.1186/1472-6750-10-56
  • CRK: An evolutionary approach for distinguishing biologically relevant interfaces from crystal contacts Scharer MA, Grutter MG, Capitani G
    PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 78, 2707 (2010).
    DOI: 10.1002/prot.22787
  • Dissecting the Relation between a Nuclear Receptor and GATA: Binding Affinity Studies of Thyroid Hormone Receptor and GATA2 on TSH? Promoter Pazin Michael J, Figueira A, Polikarpov I, Veprintsev D, Santos G
    PLOS ONE 5, e12628 (2010).
    DOI: 10.1371/journal.pone.0012628
  • Drosophila Stathmins Bind Tubulin Heterodimers with High and Variable Stoichiometries Lachkar S, Lebois M, Steinmetz MO, Guichet A, Lal N, Curmi PA, Sobel A, Ozon S
    JOURNAL OF BIOLOGICAL CHEMISTRY 285, 11667 (2010).
    DOI: 10.1074/jbc.M109.096727
  • Electron microscopy studies on the quaternary structure of p53 reveal different binding modes for p53 tetramers in complex with DNA Melero R, Rajagopalan S, Lazaro M, Joerger AC, Brandt T, Veprintsev DB, Lasso G, Gil D, Scheres SHW, Carazo JM, Fersht AR, Valle M
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 108, 557 (2010).
    DOI: 10.1073/pnas.1015520107
  • Exploring the trigger sequence of the GCN4 coiled-coil: Biased molecular dynamics resolves apparent inconsistencies in NMR measurements Missimer JH, Dolenc J, Steinmetz MO, van Gunsteren WF
    PROTEIN SCIENCE 19, 2462 (2010).
    DOI: 10.1002/pro.528
  • Features critical for membrane binding revealed by DivIVA crystal structure Oliva M, Halbedel S, Freund S, Dutow P, Leonard T, Veprintsev D, Hamoen L, Löwe J
    The EMBO Journal 29, 1988 (2010).
    DOI: 10.1038/emboj.2010.99
  • Gremlin is a novel agonist of the major proangiogenic receptor VEGFR2 Mitola S, Ravelli C, Moroni E, Salvi V, Leali D, Ballmer-Hofer K, Zammataro L, Presta M
    BLOOD 116, 3677 (2010).
    DOI: 10.1182/blood-2010-06-291930
  • In Vitro Reconstitution of the Functional Interplay between MCAK and EB3 at Microtubule Plus Ends Gouveia SM, Leslie K, Kapitein LC, Buey RM, Grigoriev I, Wagenbach M, Smal I, Meijering E, Hoogenraad CC, Wordeman L, Steinmetz MO, Akhmanova A
    CURRENT BIOLOGY 20, 1717 (2010).
    DOI: 10.1016/j.cub.2010.08.020
  • Insights into Peroxisome Function from the Structure of PEX3 in Complex with a Soluble Fragment of PEX19 Schmidt F, Treiber N, Zocher G, Bjelic S, Steinmetz MO, Kalbacher H, Stehle T, Dodt G
    JOURNAL OF BIOLOGICAL CHEMISTRY 285, 25410 (2010).
    DOI: 10.1074/jbc.M110.138503
  • Laminin chain assembly is regulated by specific coiled-coil interactions Macdonald PR, Lustig A, Steinmetz MO, Kammerer RA
    JOURNAL OF STRUCTURAL BIOLOGY 170, 398 (2010).
    DOI: 10.1016/j.jsb.2010.02.004
  • Methods of NMR structure refinement: molecular dynamics simulations improve the agreement with measured NMR data of a C-terminal peptide of GCN4-p1 Dolenc J, Missimer John H, Steinmetz Michel O, van Gunsteren Wilfred F
    JOURNAL OF BIOMOLECULAR NMR 47, 221 (2010).
    DOI: 10.1007/s10858-010-9425-9
  • Microtubule plus TIPs at a glance Akhmanova A, Steinmetz MO
    JOURNAL OF CELL SCIENCE 123, 3415 (2010).
    DOI: 10.1242/jcs.062414
  • Molecular Insights into Mammalian End-binding Protein Heterodimerization De Groot CO, Jelesarov I, Damberger FF, Bjelic S, Scharer MA, Bhavesh NS, Grigoriev I, Buey RM, Wuthrich K, Capitani G, Akhmanova A, Steinmetz MO
    JOURNAL OF BIOLOGICAL CHEMISTRY 285, 5802 (2010).
    DOI: 10.1074/jbc.M109.068130
  • Molecular basis of coiled-coil oligomerization-state specificity Ciani B, Bjelic S, Honnappa S, Jawhari H, Jaussi R, Payapilly A, Jowitt T, Steinmetz MO, Kammerer RA
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 107, 19850 (2010).
    DOI: 10.1073/pnas.1008502107
  • Nucleotide-induced global conformational changes of flagellar dynein arms revealed by in situ analysis Movassagh T, Bui K, Sakakibara H, Oiwa K, Ishikawa T
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 17, 761 (2010).
    DOI: 10.1038/nsmb.1832
  • Optimal contact definition for reconstruction of Contact Maps Duarte J, Sathyapriya R, Stehr H, Filippis I, Lappe M
    BMC BIOINFORMATICS 11, 283 (2010).
    DOI: 10.1186/1471-2105-11-283
  • PDBWiki: added value through community annotation of the Protein Data Bank Stehr H, Duarte JM, Lappe M, Bhak J, Bolser DM
    Database 2010, baq009 (2010).
    DOI: 10.1093/database/baq009
  • Phage-Derived Fully Human Monoclonal Antibody Fragments to Human Vascular Endothelial Growth Factor-C Block Its Interaction with VEGF Receptor-2 and 3 Rinderknecht M, Villa A, Ballmer-Hofer K, Neri D, Detmar M
    PLOS ONE 5, e11941 (2010).
    DOI: 10.1371/journal.pone.0011941
  • Spial: analysis of subtype-specific features in multiple sequence alignments of proteins Wuster A, Venkatakrishnan AJ, Schertler GFX, Babu MM
    BIOINFORMATICS 26, 2906 (2010).
    DOI: 10.1093/bioinformatics/btq552
  • Stable Single-Walled Carbon Nanotube-Streptavidin Complex for Biorecognition Liu Z, Galli F, Janssen Kjeld GH, Jiang L, van der Linden Heiko J, de Geus Daniel C, Voskamp P, Kuil Maxim E, Olsthoorn Rene CL, Oosterkamp TjerkH, Hankemeier T, Abrahams J
    JOURNAL OF PHYSICAL CHEMISTRY C 114, 4345 (2010).
    DOI: 10.1021/jp911441d
  • Structural determinants of growth factor binding and specificity by VEGF receptor 2 Leppanen VM, Prota AE, Jeltsch M, Anisimov A, Kalkkinen N, Strandin T, Lankinen H, Goldman A, Ballmer-Hofer K, Alitalo K
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 107, 2425 (2010).
    DOI: 10.1073/pnas.0914318107
  • Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism Bourquin F, Riezman H, Capitani G, Grutter MG
    STRUCTURE 18, 1054 (2010).
    DOI: 10.1016/j.str.2010.05.011
  • Structure of full-length arrestin2 in a dimeric crystal form Zhou H G, Standfuss J, Watson K A, Krasel C
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 381, 13-13 (2010).
  • Structure-function analysis of VEGF receptor activation and the role of coreceptors in angiogenic signaling Grunewald FS, Prota AE, Giese A, Ballmer-Hofer K
    BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS 1804, 567 (2010).
    DOI: 10.1016/j.bbapap.2009.09.002
  • The strong phase object approximation may allow extending crystallographic phases of dynamical electron diffraction patterns of 3D protein nano-crystals Abrahams J
    ZEITSCHRIFT FUR KRISTALLOGRAPHIE 225, (2010).
    DOI: 10.1524/zkri.2010.1216
  • Three-dimensional structural analysis of eukaryotic flagella/cilia by electron cryo-tomography Bui K, Pigino G, Ishikawa T
    JOURNAL OF SYNCHROTRON RADIATION 18, 2 (2010).
    DOI: 10.1107/s0909049510036812
  • Transmembrane domain-mediated orientation of receptor monomers in active VEGFR-2 dimers Dosch DD, Ballmer-Hofer K
    FASEB JOURNAL 24, 32 (2010).
    DOI: 10.1096/fj.09-132670

2009

  • A Common Structural Basis for pH- and Calmodulin-mediated Regulation in Plant Glutamate Decarboxylase Gut H, Dominici P, Pilati S, Astegno A, Petoukhov MV, Svergun DI, Grutter MG, Capitani G
    JOURNAL OF MOLECULAR BIOLOGY 392, 334 (2009).
    DOI: 10.1016/j.jmb.2009.06.080
  • An EB1-Binding Motif Acts as a Microtubule Tip Localization Signal Honnappa S, Gouveia SM, Weisbrich A, Damberger FF, Bhavesh NS, Jawhari H, Grigoriev I, van Rijssel FJA, Buey RM, Lawera A, Jelesarov I, Winkler FK, Wuthrich K, Akhmanova A, Steinmetz MO
    CELL 138, 366 (2009).
    DOI: 10.1016/j.cell.2009.04.065
  • An Intelligent Peak Search Program for Digital Electron Diffraction Images of 3D Nano-Crystals Jiang L, Georgieva D, IJspeert K, Abrahams J
    2009 2nd International Congress on Image and Signal Processing , (2009).
    DOI: 10.1109/CISP.2009.5301421
  • Asymmetry of inner dynein arms and inter-doublet links in Chlamydomonas flagella Bui K, Sakakibara H, Movassagh T, Oiwa K, Ishikawa T
    The Journal of Cell Biology 186, 437 (2009).
    DOI: 10.1083/jcb.200903082
  • Automated unrestricted multigene recombineering for multiprotein complex production Bieniossek C, Nie Y, Frey D, Olieric N, Schaffitzel C, Collinson I, Romier C, Berger P, Richmond T, Steinmetz M, Berger I
    NATURE METHODS 6, 447 (2009).
    DOI: 10.1038/nmeth.1326
  • Characterization of a diagnostic Fab fragment binding trimeric Lewis X de Geus Daniël C, van Roon AnneMarie M, Thomassen Ellen AJ, Hokke Cornelis H, Deelder André M, Abrahams J
    PROTEINS: STRUCTURE, FUNCTION, AND BIOINFORMATICS 76, 439 (2009).
    DOI: 10.1002/prot.22356
  • Crystal Structure of Chlorite Dismutase, a Detoxifying Enzyme Producing Molecular Oxygen de Geus Daniël C, Thomassen Ellen AJ, Hagedoorn P, Pannu Navraj S, van Duijn E, Abrahams J
    JOURNAL OF MOLECULAR BIOLOGY 387, 192 (2009).
    DOI: 10.1016/j.jmb.2009.01.036
  • Engineering G protein-coupled receptors to facilitate their structure determination Tate CG, Schertler GFX
    CURRENT OPINION IN STRUCTURAL BIOLOGY 19, 386 (2009).
    DOI: 10.1016/j.sbi.2009.07.004
  • Identification and structural analysis of type I collagen sites in complex with fibronectin fragments Erat MC, Slatter DA, Lowe ED, Millard CJ, Farndale RW, Campbell ID, Vakonakis I
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106, 4195 (2009).
    DOI: 10.1073/pnas.0812516106
  • Identification of the variant Ala335Val of MED25 as responsible for CMT2B2: molecular data, functional studies of the SH3 recognition motif and correlation between wild-type MED25 and PMP22 RNA levels in CMT1A animal models Leal A, Huehne K, Bauer F, Sticht H, Berger P, Suter U, Morera B, Del Valle G, Lupski James R, Ekici A, Pasutto F, Endele S, Barrantes R, Berghoff C, Berghoff M, Neundörfer B, Heuss D, Dorn T, Young P, Santolin L, Uhlmann T, Meisterernst M, Sereda M, zu Horste G, Nave K, Reis A, Rautenstrauss B
    NEUROGENETICS 10, 275 (2009).
    DOI: 10.1007/s10048-009-0183-3
  • Involvement of a carboxylated lysine in UV damage endonuclease Meulenbroek Elisabeth M, Paspaleva K, Thomassen Ellen AJ, Abrahams J, Goosen N, Pannu Navraj S
    PROTEIN SCIENCE 18, 549 (2009).
    DOI: 10.1002/pro.54
  • Latrophilin Signaling Links Anterior-Posterior Tissue Polarity and Oriented Cell Divisions in the C. elegans Embryo Langenhan T, Promel S, Mestek L, Esmaeili B, Waller-Evans H, Hennig C, Kohara Y, Avery L, Vakonakis I, Schnabel R, Russ AP
    DEVELOPMENTAL CELL 17, 494 (2009).
    DOI: 10.1016/j.devcel.2009.08.008
  • Macromolecular electron crystallography Abrahams J, Jiang L, Sikhuralidze I, Nederloff I, Zandbergen H, Georgieva D
    Acta Crystallographica Section A Foundations of Crystallography 65, s7 (2009).
    DOI: 10.1107/S0108767309099875
  • Mammalian Navigators are microtubule plus-end tracking proteins that can reorganize the cytoskeleton to induce neurite-like extensions van Haren J, Draegestein K, Keijzer N, Abrahams J, Grosveld F, Peeters P, Moechars D, Galjart N
    Cell Motility and the Cytoskeleton 66, 824 (2009).
    DOI: 10.1002/cm.20370
  • Mammalian end binding proteins control persistent microtubule growth Komarova Y, De Groot CO, Grigoriev I, Gouveia SM, Munteanu EL, Schober JM, Honnappa S, Buey RM, Hoogenraad CC, Dogterom M, Borisy GG, Steinmetz MO, Akhmanova A
    JOURNAL OF CELL BIOLOGY 184, 691 (2009).
    DOI: 10.1083/jcb.200807179
  • Medipix 2 detector applied to low energy electron microscopy van Gastel R, Sikharulidze I, Schramm S, Abrahams JP, Poelsema B, Tromp RM, van der Molen SJ
    ULTRAMICROSCOPY 110, 33 (2009).
    DOI: 10.1016/j.ultramic.2009.09.002
  • Motogenic Sites in Human Fibronectin Are Masked by Long Range Interactions Vakonakis I, Staunton D, Ellis IR, Sarkies P, Flanagan A, Schor AM, Schor SL, Campbell ID
    JOURNAL OF BIOLOGICAL CHEMISTRY 284, 15668 (2009).
    DOI: 10.1074/jbc.M109.003673
  • Mutation of His465 Alters the pH-dependent Spectroscopic Properties of Escherichia coli Glutamate Decarboxylase and Broadens the Range of Its Activity toward More Alkaline pH Pennacchietti E, Lammens TM, Capitani G, Franssen MCR, John RA, Bossa F, De Biase D
    JOURNAL OF BIOLOGICAL CHEMISTRY 284, 31587 (2009).
    DOI: 10.1074/jbc.M109.049577
  • Mutational studies of Pa-AGOG DNA glycosylase from the hyperthermophilic crenarchaeon Pyrobaculum aerophilum Lingaraju Gondichatnahalli M, Prota AE, Winkler FK
    DNA REPAIR 8, 857 (2009).
    DOI: 10.1016/j.dnarep.2009.03.009
  • Oxidoreductase activity of oligosaccharyltransferase subunits Ost3p and Ost6p defines site-specific glycosylation efficiency Schulz BL, Stirnimann CU, Grimshaw JPA, Brozzo MS, Fritsch F, Mohorko E, Capitani G, Glockshuber R, Grutter MG, Aebi M
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106, 11061 (2009).
    DOI: 10.1073/pnas.0812515106
  • Recent advances in CRANK Waterreus W, Pannu N, Skubák P, Sikharulidze I, Abrahams J, de Graaff RAG
    Acta Crystallographica Section A Foundations of Crystallography 65, s160 (2009).
    DOI: 10.1107/S0108767309096743
  • Recycling of Aborted Ribosomal 50S Subunit-Nascent Chain-tRNA Complexes by the Heat Shock Protein Hsp15 Jiang L, Schaffitzel C, Bingel-Erlenmeyer R, Ban N, Korber P, Koning Roman I, de Geus Daniël C, Plaisier Jasper R, Abrahams J
    JOURNAL OF MOLECULAR BIOLOGY 386, 1357 (2009).
    DOI: 10.1016/j.jmb.2008.10.079
  • Regulation of Microtubule Dynamic Instability in Vitro by Differentially Phosphorylated Stathmin Manna T, Thrower DA, Honnappa S, Steinmetz MO, Wilson L
    JOURNAL OF BIOLOGICAL CHEMISTRY 284, 15640 (2009).
    DOI: 10.1074/jbc.M900343200
  • Solid-State NMR Spectroscopy Reveals that E. coli Inclusion Bodies of HET-s(218 - 289) are Amyloids Wasmer C, Benkemoun L, Sabaté R, Steinmetz Michel O, Coulary-Salin B, Wang L, Riek R, Saupe Sven J, Meier Beat H
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 48, 4858 (2009).
    DOI: 10.1002/anie.200806100
  • Terminal Adenosyl Transferase Activity of Posttranscriptional Regulator HuR Revealed by Confocal On-Bead Screening Meisner N, Hintersteiner M, Seifert J, Bauer R, Benoit R, Widmer A, Schindler T, Uhl V, Lang M, Gstach H, Auer M
    JOURNAL OF MOLECULAR BIOLOGY 386, 435 (2009).
    DOI: 10.1016/j.jmb.2008.12.020
  • The Max-Inf2/Lorentz Center workshop on New algorithms in macromolecular crystallography and electron microscopy Pannu Navraj S, Ravelli Raimond BG, Abrahams J
    ACTA CRYSTALLOGRAPHICA SECTION D - BIOLOGICAL CRYSTALLOGRAPHY 65, 623 (2009).
    DOI: 10.1107/S0907444909020861
  • The second level trigger system of FAST Martinez G, Barcyzk A, Berdugo J, Casaus J, Casella C, De Laere S, Deiters K, Dick P, Kirkby J, Malgeri L, Mana C, Marin J, Pohl M, Petitjean C, Sanchez E, Willmott C
    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT 609, 235 (2009).
    DOI: 10.1016/j.nima.2009.07.097
  • The structure of an integrin/talin complex reveals the basis of inside-out signal transduction Anthis NJ, Wegener KL, Ye F, Kim C, Goult BT, Lowe ED, Vakonakis I, Bate N, Critchley DR, Ginsberg MH, Campbell ID
    EMBO JOURNAL 28, 3623 (2009).
    DOI: 10.1038/emboj.2009.287
  • Unit-cell determination from randomly oriented electron-diffraction patterns Jiang L, Georgieva D, Zandbergen Henny W, Abrahams J
    ACTA CRYSTALLOGRAPHICA SECTION D - BIOLOGICAL CRYSTALLOGRAPHY 65, 625 (2009).
    DOI: 10.1107/S0907444909003163

2008

  • A proangiogenic peptide derived from vascular endothelial growth factor receptor-1 acts through alpha 5 beta 1 integrin Soro S, Orecchia A, Morbidelli L, Lacal PM, Morea V, Ballmer-Hofer K, Ruffini F, Ziche M, D'Atri S, Zambruno G, Tramontano A, Failla CM
    BLOOD 111, 3479 (2008).
    DOI: 10.1182/blood-2007-03-077537
  • Anti-Mullerian-hormone-dependent regulation of the brain serine-protease inhibitor neuroserpin Lebeurrier N, Launay S, Macrez R, Maubert E, Legros H, Leclerc A, Jamin SP, Picard JY, Marret S, Laudenbach V, Berger P, Sonderegger P, Ali C, di Clemente N, Vivien D
    JOURNAL OF CELL SCIENCE 121, 3357 (2008).
    DOI: 10.1242/jcs.031872
  • Atomic models of de novo designed cc beta-met amyloid-like fibrils Steinmetz MO, Gattin Z, Verel R, Ciani B, Stromer T, Green JM, Tittmann P, Schulze-Bdese C, Gross H, van Gunsteren WF, Meier BH, Serpell LC, Muller SA, Kammerer RA
    JOURNAL OF MOLECULAR BIOLOGY 376, 898 (2008).
    DOI: 10.1016/j.jmb.2007.11.100
  • Capturing protein tails by CAP-Gly domains Steinmetz Michel O, Akhmanova A
    TRENDS IN BIOCHEMICAL SCIENCES 33, 535 (2008).
    DOI: 10.1016/j.tibs.2008.08.006
  • Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of chlorite dismutase: a detoxifying enzyme producing molecular oxygen de Geus Daniël C, Thomassen Ellen AJ, van der Feltz Clarisse L, Abrahams J
    Acta Crystallographica Section F Structural Biology and Crystallization Communications 64, 730 (2008).
    DOI: 10.1107/S1744309108020551
  • Crystal structure of the ternary FimC-FimF(t)-FimD(N) complex indicates conserved pilus chaperone-subunit complex recognition by the usher FimD Eidam O, Dworkowski FSN, Glockshuber R, Grutter MG, Capitani G
    FEBS LETTERS 582, 651 (2008).
    DOI: 10.1016/j.febslet.2008.01.030
  • DsbL and DsbI form a specific dithiol oxidase system for periplasmic arylsulfate sulfotransferase in uropathogenic Escherichia coli Grimshaw JPA, Stirnimann CU, Brozzo MS, Malojcic G, Gruetter MG, Capitani G, Glockshuber R
    JOURNAL OF MOLECULAR BIOLOGY 380, 667 (2008).
    DOI: 10.1016/j.jmb.2008.05.031
  • Evidence for proton shuffling in a thioredoxin-like protein during catalysis Narzi D, Siu SWI, Stirnimann CU, Grimshaw JPA, Glockshuber R, Capitani G, Bockmann RA
    JOURNAL OF MOLECULAR BIOLOGY 382, 978 (2008).
    DOI: 10.1016/j.jmb.2008.07.061
  • Exploring the Conserved Water Site and Hydration of a Coiled-Coil Trimerisation Motif: A MD Simulation Study Dolenc J, Baron R, Missimer John H, Steinmetz Michel O, van Gunsteren Wilfred F
    CHEMBIOCHEM 9, 1749 (2008).
    DOI: 10.1002/cbic.200800096
  • High-level Expression and Purification of a Designed Angiopoietin-1 Chimeric Protein, COMP-Ang1, Produced in Chinese Hamster Ovary Cells Hwang S, Kim S, Kim H, Steinmetz Michel O, Koh G, Lee G
    THE PROTEIN JOURNAL 27, 319 (2008).
    DOI: 10.1007/s10930-008-9140-5
  • Identifying key residues of sphinganine-1-phosphate lyase for function in vivo and in vitro Mukhopadhyay D, Howell KS, Riezman H, Capitani G
    JOURNAL OF BIOLOGICAL CHEMISTRY 283, 20159 (2008).
    DOI: 10.1074/jbc.M709753200
  • Infinite kinetic stability against dissociation of supramolecular protein complexes through donor strand complementation Puorger C, Eidam O, Capitani G, Erilov D, Grutter MG, Glockshuber R
    STRUCTURE 16, 631 (2008).
    DOI: 10.1016/j.str.2008.01.013
  • Microtubule Plus-End Conformations and Dynamics in the Periphery of Interphase Mouse Fibroblasts Zovko S, Abrahams JP, Koster AJ, Galjart N, Mommaas AM
    MOLECULAR BIOLOGY OF THE CELL 19, 3138 (2008).
    DOI: 10.1091/mbc.E07-07-0681
  • Molecular architecture of inner dynein arms in situ in Chlamydomonas reinhardtii flagella Bui K, Sakakibara H, Movassagh T, Oiwa K, Ishikawa T
    The Journal of Cell Biology 183, 923 (2008).
    DOI: 10.1083/jcb.200808050
  • Molecular evolution of B6 enzymes: Binding of pyridoxal-5'-phosphate and Lys41Arg substitution turn ribonuclease A into a model B6 protoenzyme Vacca R, Giannattasio S, Capitani G, Marra E, Christen P
    BMC BIOCHEMISTRY 9, 17 (2008).
    DOI: 10.1186/1471-2091-9-17
  • Neuropilin-1 in regulation of VEGF-induced activation of p38MAPK and endothelial cell organization Kawamura H, Li XJ, Goishi K, van Meeteren LA, Jakobsson L, Cebe-Suarez S, Shimizu A, Edholm D, Ballmer-Hofer K, Kjellen L, Klagsbrun M, Claesson-Welsh L
    BLOOD 112, 3638 (2008).
    DOI: 10.1182/blood-2007-12-125856
  • Orf virus VEGF-E NZ2 promotes paracellular NRP-1/VEGFR-2 coreceptor assembly via the peptide RPPR Cebe-Suarez P, Grunewald FS, Jaussi R, Li XJ, Claesson-Welsh L, Spillmann D, Mercer AA, Prota AE, Ballmer-Hofer K
    FASEB JOURNAL 22, 3078 (2008).
    DOI: 10.1096/fj.08-107219
  • Polymorphism in an Amyloid-Like Fibril-Forming Model Peptide Verel R, Tomka Ivan T, Bertozzi C, Cadalbert R, Kammerer Richard A, Steinmetz MO, Meier Beat H
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 47, 5842 (2008).
    DOI: 10.1002/anie.200800021
  • Prospects for structure solution by electron diffraction of three-dimensional protein crystals Abrahams JP, Georgieva D, Jiang L, Zandbergen HW
    Acta Crystallographica Section A Foundations of Crystallography 64, C75 (2008).
    DOI: 10.1107/S0108767308097584
  • STIM1 is a MT-plus-end-tracking protein involved in remodeling of the ER Grigoriev I, Gouveia S, Van der Vaart B, Demmers J, Smyth JT, Honnappa S, Splinter D, Steinmetz MO, Putney JW, Hoogenraad CC, Akhmanova A
    CURRENT BIOLOGY 18, 177 (2008).
    DOI: 10.1016/j.cub.2007.12.050
  • Suppression of Microtubule Dynamic Instability by the +TIP Protein EB1 and Its Modulation by the CAP-Gly Domain of p150 Glued ? Manna T, Honnappa S, Steinmetz Michel O, Wilson L
    BIOCHEMISTRY 47, 779 (2008).
    DOI: 10.1021/bi701912g
  • Suppression of microtubule dynamic instability by the plus TIP protein EB1 and its modulation by the CAP-Gly domain of p150(Glued) Manna Tapas, Honnappa Srinivas, Steinmetz Michel O, Wilson Leslie
    BIOCHEMISTRY 47, 779-786 (2008).
    DOI: 10.1021/bi701912g
  • Tracking the ends: a dynamic protein network controls the fate of microtubule tips Akhmanova A, Steinmetz Michel O
    NATURE REVIEWS MOLECULAR CELL BIOLOGY 9, 309 (2008).
    DOI: 10.1038/nrm2369

2007

  • Announcement of the editor-in-chief Cebe-Suarez S, Zehnder-Fjallman A, Ballmer-Hofer K
    CELLULAR AND MOLECULAR LIFE SCIENCES 64, I (2007).
    DOI: 10.1007/s00018-007-7003-4
  • Configurational entropy elucidates the role of salt-bridge networks in protein thermostability Missimer JH, Steinmetz MO, Baron R, Winkler FK, Kammerer Richard A, Daura X, van Gunsteren Wilfred F
    PROTEIN SCIENCE 16, 1349 (2007).
    DOI: 10.1110/ps.062542907
  • Crystal Structure of the DNA Repair Enzyme Ultraviolet Damage Endonuclease Paspaleva K, Thomassen E, Pannu Navraj S, Iwai S, Moolenaar Geri F, Goosen N, Abrahams J
    STRUCTURE 15, 1316 (2007).
    DOI: 10.1016/j.str.2007.05.010
  • Cyclops: New modular software suite for cryo-EM Plaisier JR, Jiang L, Abrahams JP
    JOURNAL OF STRUCTURAL BIOLOGY 157, 19 (2007).
    DOI: 10.1016/j.jsb.2006.07.002
  • Early segregation of layered projections from the lateral superior olivary nucleus to the central nucleus of the inferior colliculus in the neonatal cat Gabriele Mark L, Shahmoradian SH, French Christopher C, Henkel Craig K, McHaffie John G
    BRAIN RESEARCH 1173, 66 (2007).
    DOI: 10.1016/j.brainres.2007.07.055
  • Heterogeneous nucleation of three-dimensional protein nanocrystals Georgieva Dilyana G, Kuil Maxim E, Oosterkamp Tjerk H, Zandbergen Henny W, Abrahams J
    ACTA CRYSTALLOGRAPHICA SECTION D - BIOLOGICAL CRYSTALLOGRAPHY 63, 564 (2007).
    DOI: 10.1107/S0907444907007810
  • Molecular basis of coiled-coil formation Steinmetz MO, Jelesarov I, Matousek WM, Honnappa S, Jahnke W, Missimer JH, Frank S, Alexandrescu AT, Kammerer RA
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 104, 7062 (2007).
    DOI: 10.1073/pnas.0700321104
  • Motor Neuron Disease-Associated Mutant Vesicle-Associated Membrane Protein-Associated Protein (VAP) B Recruits Wild-Type VAPs into Endoplasmic Reticulum-Derived Tubular Aggregates Teuling E, Ahmed S, Haasdijk E, Demmers J, Steinmetz MO, Akhmanova A, Jaarsma D, Hoogenraad CC
    JOURNAL OF NEUROSCIENCE 27, 9801 (2007).
    DOI: 10.1523/jneurosci.2661-07.2007
  • Mtmr13/Sbf2-deficient mice: an animal model for CMT4B2 Tersar K, Boentert M, Berger P, Bonneick S, Wessig C, Toyka KV, Young P, Suter U
    HUMAN MOLECULAR GENETICS 16, 2991 (2007).
    DOI: 10.1093/hmg/ddm257
  • Multiprotein Expression Strategy for Structural Biology of Eukaryotic Complexes Fitzgerald Daniel J, Schaffitzel C, Berger P, Wellinger R, Bieniossek C, Richmond Timothy J, Berger I
    STRUCTURE 15, 275 (2007).
    DOI: 10.1016/j.str.2007.01.016
  • Production of in vitro amplified DNA pseudolibraries and high-throughput cDNA target amplification Frey D, Kambach C, Steinmetz M, Jaussi R
    BMC BIOTECHNOLOGY 7, 31 (2007).
    DOI: 10.1186/1472-6750-7-31
  • Recent advances in the CRANK automated structure solution suite Pannu NS, Skubak P, Sikharulidze I, Abrahams JP, de Graaff RAG
    Acta Crystallographica Section A Foundations of Crystallography 63, s116 (2007).
    DOI: 10.1107/S0108767307097516
  • Solving Ab-initio Protein and Nanostructures with Precession Electron Diffraction Georgieva D, Abrahams J, Zandbergen H, Nikolopoulos S, Boulahya K
    MICROSCOPY AND MICROANALYSIS 13, (2007).
    DOI: 10.1017/S1431927607072698
  • Structural and mechanistic aspects of Amt/Rh proteins Javelle A, Lupo D, Li X, Merrick M, Chami M, Ripoche P, Winkler FK
    JOURNAL OF STRUCTURAL BIOLOGY 158, 472 (2007).
    DOI: 10.1016/j.jsb.2007.01.004
  • Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis (vol 104, July, pg 12151, 2007) Scherr N, Hormappa S, Kunz GR, Mueller P, Jayachandran R, Winkler F, Pieters J, Steinmetz MO
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 104, 16388 (2007).
    DOI: 10.1073/pnas.0708192104
  • Structure and thermodynamics of the tubulin?stathmin interaction Steinmetz Michel O
    JOURNAL OF STRUCTURAL BIOLOGY 158, 137 (2007).
    DOI: 10.1016/j.jsb.2006.07.018
  • Structure of a VEGF-VEGF receptor complex determined by electron microscopy Ruch C, Skiniotis G, Steinmetz MO, Walz T, Ballmer-Hofer K
    NATURE STRUCTURAL AND MOLECULAR BIOLOGY 14, 249 (2007).
    DOI: 10.1038/nsmb1202
  • Structure of the E. coli signal recognition particle bound to a translating ribosome Schaffitzel C, Oswald M, Berger I, Ishikawa T, Abrahams J, Koerten Henk K, Koning Roman I, Ban N
    NATURE 448, 1076 (2007).
    DOI: 10.1038/nature06169
  • Structure-function relationship of CAP-Gly domains Weisbrich A, Honnappa S, Jaussi R, Okhrimenko O, Frey D, Jelesarov I, Akhmanova A, Steinmetz MO
    NATURE STRUCTURAL AND MOLECULAR BIOLOGY 14, 959 (2007).
    DOI: 10.1038/nsmb1291
  • The 1.3-A resolution structure of nitrosomas erropea Rh50 and mechanistic implications for NH3 transport by Rhesus family proteins Lupo D, Li XD, Durand A, Tomizaki T, Cherif-zahar B, Matassi G, Merrik M, Winkler FK
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 50, 577 (2007).
  • The Caenorhabditis elegans septin complex is nonpolar John C, Hite R, Weirich C, Fitzgerald D, Jawhari H, Faty M, Schläpfer D, Kroschewski R, Winkler F, Walz T, Barral Y, Steinmetz M
    The EMBO Journal 26, 3296 (2007).
    DOI: 10.1038/sj.emboj.7601775
  • The crystal structure of the Escherichia coli AmtB-GlnK complex reveals how GlnK regulates the ammonia channel Conroy MJ, Durand A, Lupo D, Li XD, Bullough PA, Winkler FK, Merrick M
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 104, 1213 (2007).
    DOI: 10.1073/pnas.0610348104

2006

  • 13C, 15N Resonance Assignment of Parts of the HET-s Prion Protein in its Amyloid Form Siemer Ansgar B, Ritter C, Steinmetz Michel O, Ernst M, Riek R, Meier Beat H
    JOURNAL OF BIOMOLECULAR NMR 34, 75 (2006).
    DOI: 10.1007/s10858-005-5582-7
  • An improved method for fast, robust, and seamless integration of DNA fragments into multiple plasmids Benoit RM, Wilhelm RN, Scherer-Becker D, Ostermeier C
    PROTEIN EXPRESSION AND PURIFICATION 45, 66-71 (2006).
    DOI: 10.1016/j.pep.2005.09.022
  • C-13, N-15 resonance assignment of parts of the HET-s prion protein in its amyloid form Siemer AB, Ritter C, Steinmetz MO, Ernst M, Riek R, Meier BH
    JOURNAL OF BIOMOLECULAR NMR 34, 75-87 (2006).
    DOI: 10.1007/s10858-005-5582-7
  • Control of Intrinsically Disordered Stathmin by Multisite Phosphorylation Honnappa S, Jahnke W, Seelig J, Steinmetz MO
    JOURNAL OF BIOLOGICAL CHEMISTRY 281, 16078 (2006).
    DOI: 10.1074/jbc.M513524200
  • De novo design of a two-stranded coiled-coil switch peptide Kammerer Richard A, Steinmetz MO
    JOURNAL OF STRUCTURAL BIOLOGY 155, 146 (2006).
    DOI: 10.1016/j.jsb.2006.01.017
  • Evidence for a novel domain of bacterial outer membrane ushers Capitani G, Eidam O, Grutter MG
    PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 65, 816 (2006).
    DOI: 10.1002/prot.21147
  • Multi-level regulation of myotubularin-related protein-2 phosphatase activity by myotubularin-related protein-13/set-binding factor-2 Berger P, Berger I, Schaffitzel C, Tersar K, Volkmer B, Suter U
    HUMAN MOLECULAR GENETICS 15, 569 (2006).
    DOI: 10.1093/hmg/ddi473
  • Nano-dispensing by electrospray for biotechnology Kuil Maxim E, Abrahams J, Marijnissen Jan CM
    Biotechnology Journal 1, 969 (2006).
    DOI: 10.1002/biot.200600062
  • Pathomechanisms of mutant proteins in Charcot-Marie-Tooth disease Niemann A, Berger P, Suter U
    NEUROMOLECULAR MEDICINE 8, 217 (2006).
    DOI: 10.1385/NMM:8:1:217
  • Protein complex expression by using multigene baculoviral vectors Fitzgerald D, Berger P, Schaffitzel C, Yamada K, Richmond T, Berger I
    NATURE METHODS 3, 1021 (2006).
    DOI: 10.1038/nmeth983
  • Schwann cells and the pathogenesis of inherited motor and sensory neuropathies (Charcot-Marie-Tooth disease) Berger P, Niemann A, Suter U
    GLIA 54, 243 (2006).
    DOI: 10.1002/glia.20386
  • Structural and functional insights into the AmtB/Mep/Rh protein family Li XD, Lupo D, Zheng L, Winkler F
    TRANSFUSION CLINIQUE ET BIOLOGIQUE 13, 65 (2006).
    DOI: 10.1016/j.tracli.2006.02.014
  • Structure of the E. coli signal recognition particle bound to a translating ribosome Schaffitzel C, Oswald M, Berger I, Ishikawa T, Abrahams J, Koerten Henk K, Koning Roman I, Ban N
    NATURE 444, 503 (2006).
    DOI: 10.1038/nature05182
  • Structure of the Extracellular Domain of Tie Receptor Tyrosine Kinases and Localization of the Angiopoietin-binding Epitope Macdonald PR, Progias P, Ciani B, Patel S, Mayer U, Steinmetz MO, Kammerer RA
    JOURNAL OF BIOLOGICAL CHEMISTRY 281, 28408 (2006).
    DOI: 10.1074/jbc.M605219200
  • The Impact of Single Amino Acid Substitutions in CD3? on the CD3?? Interaction and T-Cell Receptor?CD3 Complex Formation Thomassen EAJ, Dekking EHA, Thompson A, Franken KL, Sanal Ö, Abrahams JP, van Tol MJD, Koning F
    HUMAN IMMUNOLOGY 67, 579 (2006).
    DOI: 10.1016/j.humimm.2006.04.015

2005

  • A conserved trimerization motif controls the topology of short coiled coils Kammerer RA, Kostrewa D, Progias P, Honnappa S, Avila D, Lustig A, Winkler FK, Pieters J, Steinmetz MO
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102, 13891-13896 (2005).
    DOI: 10.1073/pnas.0502390102
  • Association of the leukocyte plasma membrane with the actin cytoskeleton through coiled coil-mediated trimeric coronin 1 molecules Gatfield J, Albrecht I, Zanolari B, Steinmetz MO, Pieters J
    MOLECULAR BIOLOGY OF THE CELL 16, 2786-2798 (2005).
  • Design of a coiled-coil-based model peptide system to explore the fundamentals of amyloid fibril formation Steinmetz MO, Garcia-Echeverria C, Kammerer RA
    International Journal of Peptide Research and Therapeutics 11, 43-52 (2005).
    DOI: 10.1007/s10989-004-1720-4
  • Molecular-dynamics simulations of C- and N-terminal peptide derivatives of GCN4-p1 in aqueous solution Missimer JH, Steinmetz MO, Jahnke W, Winkler FK, van Gunsteren WF, Daura X
    Chemistry & Biodiversity 2, 1086-1104 (2005).
  • Oligomerization and multimerization are critical for angiopoietin-1 to bind and phosphorylate Tie2 Kim KT, Choi HH, Steinmetz MO, Maco B, Kammerer RA, Ahn SY, Kim HZ, Lee GM, Koh GY
    JOURNAL OF BIOLOGICAL CHEMISTRY 280, 20126-20131 (2005).
    DOI: 10.1074/jbc.M500292200
  • Structural and functional analysis of coronin 1 Albrecht I, Gatfield J, Zanolari B, Steinmetz MO, Pieters J
    FEBS JOURNAL 272, 320-321 (2005).
  • Structural basis for the regulation of tubulin by vinblastine Gigant B, Wang CG, Ravelli RBG, Roussi F, Steinmetz MO, Curmi PA, Sobel A, Knossow M
    NATURE 435, 519-522 (2005).
    DOI: 10.1038/nature03566
  • Structural insights into the EB1-APC interaction Honnappa S, John CM, Kostrewa D, Winkler FK, Steinmetz MO
    EMBO JOURNAL 24, 261 (2005).
    DOI: 10.1038/sj.emboj.7600529
  • Structural insights into the EB1-APC interaction (vol 24, pg 261, 2005) Honnappa S, John CM, Kostrewa D, Winkler FK, Steinmetz MO
    EMBO JOURNAL 24, 872-872 (2005).
    DOI: 10.1038/sj.emboj.7600590

2004

  • A Molecular Dynamics Study of Reovirus Attachment Protein ?1 Reveals Conformational Changes in ?1 Structure Cavalli A, Prota AE, Stehle T, Dermody Terence S, Recanatini M, Folkers G, Scapozza L
    BIOPHYSICAL JOURNAL 86, 3423 (2004).
    DOI: 10.1529/biophysj.103.030825
  • COMP-Ang1: A designed angiopoietin-1 variant with nonleaky angiogenic activity Cho CH, Kammerer RA, Lee HJ, Steinmetz MO, Ryu YS, Lee SH, Yasunaga K, Kim KT, Kim I, Choi HH, Kim W, Kim SH, Park SK, Lee GM, Koh GY
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101, 5547-5552 (2004).
    DOI: 10.1073/pnas.0307574101
  • Exploring amyloid formation by a de novo design Kammerer RA, Kostrewa D, Zurdo J, Detken A, Garcia-Echeverria C, Green JD, Muller SA, Meier BH, Winkler FK, Dobson CM, Steinmetz MO
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101, 4435-4440 (2004).
    DOI: 10.1073/pnas.0306786101

2003

  • Crystal structure of human junctional adhesion molecule 1: Implications for reovirus binding Prota AE, Campbell JA, Schelling P, Forrest JC, Watson MJ, Peters TR, Aurrand-Lions M, Imhof BA, Dermody TS, Stehle T
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100, 5366 (2003).
    DOI: 10.1073/pnas.0937718100
  • Thermodynamics of the Op18/stathmin-tubulin interaction Honnappa S, Cutting B, Jahnke W, Seelig J, Steinmetz MO
    JOURNAL OF BIOLOGICAL CHEMISTRY 278, 38926-38934 (2003).
    DOI: 10.1074/jbc.M305546200

2002

  • The crystal structure of human CD21: Implications for Epstein-Barr virus and C3d binding Prota AE, Sage DR, Stehle T, Fingeroth JD
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99, 10641 (2002).
    DOI: 10.1073/pnas.162360499

Laboratory of Biomolecular Research

Secretariat

Anita Strittmatter
Secretary

Paul Scherrer Institut
Department of Biology and Chemistry
OFLC/108
Forschungsstrasse 111
CH-5232 Villigen PSI
Switzerland

Telephone: +41 56 310 20 35
Fax: +41 56 310 21 99
E-mail: anita.strittmatter@psi.ch

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