Publications
X10SA PDB Structure Gallery from BioSync
PXII Publications
Recent publications are listed below. For an extensive overview we kindly refer you to our publication repository DORA
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Johansson E, Wu X, Yu B, Yang Z, Cao Z, Wiberg C, et al.
Insulin binding to the analytical antibody sandwich pair OXI‐005 and HUI‐018: epitope mapping and binding properties
Protein Science. 2021; 30(2): 485-496. https://doi.org/10.1002/pro.4009
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Schutzius G, Kolter C, Bergling S, Tortelli F, Fuchs F, Renner S, et al.
BET bromodomain inhibitors regulate keratinocyte plasticity
Nature Chemical Biology. 2021. https://doi.org/10.1038/s41589-020-00716-z
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Thomson CG, Le Grand D, Dowling M, Beattie D, Elphick L, Faller M, et al.
Development of autotaxin inhibitors: a series of tetrazole cinnamides
Bioorganic and Medicinal Chemistry Letters. 2021; 31: 127663 (7 pp.). https://doi.org/10.1016/j.bmcl.2020.127663
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't Hart P, Hommen P, Noisier A, Krzyzanowski A, Schüler D, Porfetye AT, et al.
Structure based design of bicyclic Peptide inhibitors of RbAp48
Angewandte Chemie International Edition. 2020. https://doi.org/10.1002/anie.202009749
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Ajam T, De I, Petkau N, Whelan G, Pena V, Eichele G
Alternative catalytic residues in the active site of Esco acetyltransferases
Scientific Reports. 2020; 10(1): 9828 (13 pp.). https://doi.org/10.1038/s41598-020-66795-z
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Angst D, Gessier F, Janser P, Vulpetti A, Wälchli R, Beerli C, et al.
Discovery of LOU064 (remibrutinib), a potent and highly selective covalent inhibitor of Bruton's tyrosine kinase
Journal of Medicinal Chemistry. 2020; 63(10): 5102-5118. https://doi.org/10.1021/acs.jmedchem.9b01916
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Bokhovchuk F, Mesrouze Y, Delaunay C, Martin T, Villard F, Meyerhofer M, et al.
Identification of FAM181A and FAM181B as new interactors with the TEAD transcription factors
Protein Science. 2020; 29(2): 509-520. https://doi.org/10.1002/pro.3775
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Borreschmidt Hansen B, Jepsen TH, Larsen M, Sindet R, Vifian T, Nørreskov Burhardt M, et al.
Fragment-based discovery of pyrazolopyridones as JAK1 inhibitors with excellent subtype selectivity
Journal of Medicinal Chemistry. 2020; 63(3): 7008-7032. https://doi.org/10.1021/acs.jmedchem.0c00359
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Buonfiglio R, Prati F, Bischetti M, Cavarischia C, Furlotti G, Ombrato R
Discovery of novel imidazopyridine GSK-3β inhibitors supported by cmputational approaches
Molecules. 2020; 25(9): 2163 (29 pp.). https://doi.org/10.3390/molecules25092163
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Cheng R, Huang C-Y, Hennig M, Nar H, Schnapp G
In situ crystallography as an emerging method for structure solution of membrane proteins: the case of CCR2A
FEBS Journal. 2020; 287(5): 866-873. https://doi.org/10.1111/febs.15098
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Cuozzo JW, Clark MA, Keefe AD, Kohlmann A, Mulvihill M, Ni H, et al.
Novel autotaxin inhibitor for the treatment of idiopathic pulmonary fibrosis: a clinical candidate discovered using DNA-encoded chemistry
Journal of Medicinal Chemistry. 2020; 63(14): 7840-7856. https://doi.org/10.1021/acs.jmedchem.0c00688
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DeRatt LG, Pietsch EC, Tanner A, Shaffer P, Jacoby E, Wang W, et al.
A carboxylic acid isostere screen of the DHODH inhibitor Brequinar
Bioorganic and Medicinal Chemistry Letters. 2020; 30(22): 127589 (5 pp.). https://doi.org/10.1016/j.bmcl.2020.127589
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Dengl S, Mayer K, Bormann F, Duerr H, Hoffmann E, Nussbaum B, et al.
Format chain exchange (FORCE) for high-throughput generation of bispecific antibodies in combinatorial binder-format matrices
Nature Communications. 2020; 11(1): 4974 (11 pp.). https://doi.org/10.1038/s41467-020-18477-7
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Dodonova SO, Zhu F, Dienemann C, Taipale J, Cramer P
Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function
Nature. 2020; 580(7805): 669-672. https://doi.org/10.1038/s41586-020-2195-y
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Drew SL, Thomas-Tran R, Beatty JW, Fournier J, Lawson KV, Miles DH, et al.
Discovery of potent and selective PI3Kγ inhibitors
Journal of Medicinal Chemistry. 2020; 63(19): 11235-11257. https://doi.org/10.1021/acs.jmedchem.0c01203
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Du X, Moore J, Blank BR, Eksterowicz J, Sutimantanapi D, Yuen N, et al.
Orally bioavailable small-molecule CD73 inhibitor (OP-5244) reverses immunosuppression through blockade of adenosine production
Journal of Medicinal Chemistry. 2020; 63(18): 10433-10459. https://doi.org/10.1021/acs.jmedchem.0c01086
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Ebenhoch R, Prinz S, Kaltwasser S, Mills DJ, Meinecke R, Rübbelke M, et al.
A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2020; 117(50): 31838-31849. https://doi.org/10.1073/pnas.2013473117
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Erdogan M, Fabritius A, Basquin J, Griesbeck O
Targeted in situ protein diversification and intra-organelle validation in mammalian cells
Cell Chemical Biology. 2020; 27(5): 610-621. https://doi.org/10.1016/j.chembiol.2020.02.004
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Ernst C, Kayastha K, Koch T, Venceslau SS, Pereira IAC, Demmer U, et al.
Structural and spectroscopic characterization of a HdrA-like subunit from Hyphomicrobium denitrificans
FEBS Journal. 2020. https://doi.org/10.1111/febs.15505
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Farrants H, Tarnawski M, Müller TG, Otsuka S, Hiblot J, Koch B, et al.
Chemogenetic control of nanobodies
Nature Methods. 2020; 17(3): 279-282. https://doi.org/10.1038/s41592-020-0746-7
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Favretto F, Baker JD, Strohäker T, Andreas LB, Blair LJ, Becker S, et al.
The molecular basis of the interaction of cyclophilin A with α-synuclein
Angewandte Chemie International Edition. 2020; 59(14): 5692-5695. https://doi.org/10.1002/anie.201914878
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Fuchs A-L, Wurm JP, Neu A, Sprangers R
Molecular basis of the selective processing of short mRNA substrates by the DcpS mRNA decapping enzyme
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2020; 117(32): 19237-19244. https://doi.org/10.1073/pnas.2009362117
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Gasser C, Delazer I, Neuner E, Pascher K, Brillet K, Klotz S, et al.
Thioguanosine conversion enables mRNA-lifetime evaluation by RNA sequencing using double metabolic labeling (TUC-seq DUAL)
Angewandte Chemie International Edition. 2020; 59(17): 6881-6886. https://doi.org/10.1002/anie.201916272
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Goepfert A, Lehmann S, Blank J, Kolbinger F, Rondeau JM
Structural analysis reveals that the cytokine IL-17F forms a homodimeric complex with receptor IL-17RC to drive IL-17RA-independent signaling
Immunity. 2020; 52(3): 499-512. https://doi.org/10.1016/j.immuni.2020.02.004
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Haltenhof T, Kotte A, De Bortoli F, Schiefer S, Meinke S, Emmerichs A-K, et al.
A conserved kinase-based body-temperature sensor globally controls alternative splicing and gene expression
Molecular Cell. 2020; 78(1): 57-69.e4. https://doi.org/10.1016/j.molcel.2020.01.028
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He Q, Toh JD, Ero R, Qiao Z, Kumar V, Serra A, et al.
The unusual di-domain structure of Dunaliella salina glycerol-3-phosphate dehydrogenase enables direct conversion of dihydroxyacetone phosphate to glycerol
Plant Journal. 2020; 102(1): 153-164. https://doi.org/10.1111/tpj.14619
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Hu Z, Wang C, Glunz PW, Li J, Cheadle NL, Chen AY, et al.
Discovery of a phenylpyrazole amide ROCK inhibitor as a tool molecule for in vivo studies
Bioorganic and Medicinal Chemistry Letters. 2020; 30(21): 127495 (4 pp.). https://doi.org/10.1016/j.bmcl.2020.127495
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Huang C-Y, Olieric V, Caffrey M, Wang M
In meso in situ serial X-Ray crystallography (IMISX): a protocol for membrane protein structure determination at the Swiss Light Source
In: Perez C, Maier T, eds. Expression, purification, and structural biology of membrane proteins. Methods in molecular biology. New York: Humana; 2020:293-319. https://doi.org/10.1007/978-1-0716-0373-4_20
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Huang G, Wagner T, Demmer U, Warkentin E, Ermler U, Shima S
The hydride transfer process in NADP-dependent methylene-tetrahydromethanopterin dehydrogenase
Journal of Molecular Biology. 2020; 432(7): 2042-2054. https://doi.org/10.1016/j.jmb.2020.01.042
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Hughes N, Erbel P, Bornancin F, Wiesmann C, Schiering N, Villard F, et al.
Stabilizing inactive conformations of MALT1 as an effective approach to inhibit its protease activity
Advanced Therapeutics. 2020; 3(9): 2000078 (8 pp.). https://doi.org/10.1002/adtp.202000078
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Huwald D, Duda S, Gasper R, Olieric V, Hofmann E, Hemschemeier A
Distinctive structural properties of THB11, a pentacoordinate Chlamydomonas reinhardtii truncated hemoglobin with N- and C-terminal extensions
Journal of Biological Inorganic Chemistry. 2020; 25: 267-283. https://doi.org/10.1007/s00775-020-01759-2
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Kalliokoski T, Rummakko P, Rantanen M, Blaesse M, Augustin M, Ummenthala GR, et al.
Discovery of sulfonamides and 9-oxo-2,8-diazaspiro[5,5]undecane-2-carboxamides as human kynurenine aminotransferase 2 (KAT2) inhibitors
Bioorganic and Medicinal Chemistry Letters. 2020; 30(8): 127060 (6 pp.). https://doi.org/10.1016/j.bmcl.2020.127060
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Katayama K, Ishii K, Tsuda E, Yotsumoto K, Hiramoto K, Suzuki M, et al.
Discovery of novel histone lysine methyltransferase G9a/GLP (EHMT2/1) inhibitors: Design, synthesis, and structure-activity relationships of 2,4-diamino-6-methylpyrimidines
Bioorganic and Medicinal Chemistry Letters. 2020; 30(20): 127475 (5 pp.). https://doi.org/10.1016/j.bmcl.2020.127475
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Kawanami T, Karki RG, Cody E, Liu Q, Liang G, Ksander GM, et al.
Structure-guided design of substituted biphenyl butanoic acid derivatives as neprilysin inhibitors
ACS Medicinal Chemistry Letters. 2020; 11(2): 188-194. https://doi.org/10.1021/acsmedchemlett.9b00578
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Knoepfel T, Nimsgern P, Jacquier S, Bourrel M, Vangrevelinghe E, Glatthar R, et al.
Target-based identification and optimization of 5-indazol-5-yl pyridones as Toll-like receptor 7 and 8 antagonists using a biochemical TLR8 antagonist competition assay
Journal of Medicinal Chemistry. 2020; 63(15): 8276-8295. https://doi.org/10.1021/acs.jmedchem.0c00130
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Lampret O, Duan J, Hofmann E, Winkler M, Armstrong FA, Happe T
The roles of long-range proton-coupled electron transfer in the directionality and efficiency of [FeFe]-hydrogenases
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2020; 117(34): 20520-20529. https://doi.org/10.1073/pnas.2007090117
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Lategahn J, Hardick J, Grabe T, Niggenaber J, Jeyakumar K, Keul M, et al.
Targeting Her2-insYVMA with covalent inhibitors - a focused compound screening and structure-based design approach
Journal of Medicinal Chemistry. 2020; 63(20): 11725-11755. https://doi.org/10.1021/acs.jmedchem.0c00870
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Leger PR, Hu DX, Biannic B, Bui M, Han X, Karbarz E, et al.
Discovery of potent, selective, and orally bioavailable inhibitors of USP7 with in vivo antitumor activity
Journal of Medicinal Chemistry. 2020; 63(10): 5398-5420. https://doi.org/10.1021/acs.jmedchem.0c00245
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Liu Y, Wu J, Zhou M, Chen W, Li D, Wang Z, et al.
Discovery of 3-pyridyl isoindolin-1-one derivatives as potent, selective, and orally active aldosterone synthase (CYP11B2) inhibitors
Journal of Medicinal Chemistry. 2020; 63(13): 6876-6897. https://doi.org/10.1021/acs.jmedchem.0c00233
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Lorthiois E, Roache J, Barnes-Seeman D, Altmann E, Hassiepen U, Turner G, et al.
Structure-based design and preclinical characterization of selective and orally bioavailable factor XIa inhibitors: demonstrating the power of an integrated S1 protease family approach
Journal of Medicinal Chemistry. 2020; 63(15): 8088-8113. https://doi.org/10.1021/acs.jmedchem.0c00279
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Lunk I, Litty FA, Hennig S, Vetter IR, Kotthaus J, Altmann KS, et al.
Discovery of N-(4-Aminobutyl)-N′-(2-methoxyethyl)guanidine as the first selective, nonamino acid, catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1)
Journal of Medicinal Chemistry. 2020; 63(1): 425-432. https://doi.org/10.1021/acs.jmedchem.9b01230
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Lučić M, Svistunenko DA, Wilson MT, Chaplin AK, Davy B, Ebrahim A, et al.
Serial femtosecond zero dose crystallography captures a water-free distal heme site in a dye‐decolourising peroxidase to reveal a catalytic role for an arginine in FeIV=O formation
Angewandte Chemie International Edition. 2020. https://doi.org/10.1002/anie.202008622
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Mainolfi N, Ehara T, Karki RG, Anderson K, Mac Sweeney A, Liao SM, et al.
Discovery of 4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic acid (LNP023), a factor B inhibitor specifically designed to be applicable to treating a diverse array of complement mediated diseases
Journal of Medicinal Chemistry. 2020; 63: 5697-5722. https://doi.org/10.1021/acs.jmedchem.9b01870
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Martiel I, Buntschu D, Meier N, Gobbo A, Panepucci E, Schneider R, et al.
The TELL automatic sample changer for macromolecular crystallography
Journal of Synchrotron Radiation. 2020; 27: 860-863. https://doi.org/10.1107/S1600577520002416
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Mehr A, Henneberg F, Chari A, Görlich D, Huyton T
The copper(II)-binding tripeptide GHK, a valuable crystallization and phasing tag for macromolecular crystallography
Acta Crystallographica Section D: Structural Biology. 2020; 76(12): 1222-1232. https://doi.org/10.1107/S2059798320013741
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Mesrouze Y, Aguilar G, Bokhovchuk F, Martin T, Delaunay C, Villard F, et al.
A new perspective on the interaction between the Vg/VGLL1-3 proteins and the TEAD transcription factors
Scientific Reports. 2020; 10: 17442 (12 pp.). https://doi.org/10.1038/s41598-020-74584-x
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Metrick CM, Peterson EA, Santoro JC, Enyedy IJ, Murugan P, Chen TY, et al.
Human PLD structures enable drug design and characterization of isoenzyme selectivity
Nature Chemical Biology. 2020; 16: 391-399. https://doi.org/10.1038/s41589-019-0458-4
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Mishra A, Castañeda TR, Bader E, Elshorst B, Cummings S, Scherer P, et al.
Triantennary GalNAc molecular imaging probes for monitoring hepatocyte function in a rat model of nonalcoholic steatohepatitis
Advanced Science. 2020; 7(24): 2002997 (9 pp.). https://doi.org/10.1002/advs.202002997
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Niggenaber J, Heyden L, Grabe T, Muller MP, Lategahn J, Rauh D
Complex crystal structures of EGFR with third-generation kinase inhibitors and simultaneously bound allosteric ligands
ACS Medicinal Chemistry Letters. 2020; 11(12): 2484-2490. https://doi.org/10.1021/acsmedchemlett.0c00472
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Overdijk MB, Strumane K, Beurskens FJ, Ortiz Buijsse A, Vermot-Desroches C, Vuillermoz BS, et al.
Dual epitope targeting and enhanced hexamerization by DR5 antibodies as a novel approach to induce potent antitumor activity through DR5 agonism
Molecular Cancer Therapeutics. 2020; 19(10): 2126-2138. https://doi.org/10.1158/1535-7163.MCT-20-0044
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Pantoom S, Konstantinidis G, Voss S, Han H, Hofnagel O, Li Z, et al.
RAB33B recruits the ATG16L1 complex to the phagophore via a noncanonical RAB binding protein
Autophagy. 2020. https://doi.org/10.1080/15548627.2020.1822629
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Parks CD, Gaieb Z, Chiu M, Yang H, Shao C, Walters WP, et al.
D3R grand challenge 4: blind prediction of protein-ligand poses, affinity rankings, and relative binding free energies
Journal of Computer-Aided Molecular Design. 2020; 34(2): 99-119. https://doi.org/10.1007/s10822-020-00289-y
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Pissot Soldermann C, Simic O, Renatus M, Erbel P, Melkko S, Wartmann M, et al.
Discovery of potent, highly selective, and in vivo efficacious, allosteric MALT1 inhibitors by iterative scaffold morphing
Journal of Medicinal Chemistry. 2020; 63(23): 14576-14593. https://doi.org/10.1021/acs.jmedchem.0c01245
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Prati F, Buonfiglio R, Furlotti G, Cavarischia C, Mangano G, Picollo R, et al.
Optimization of indazole-based GSK-3 inhibitors with mitigated hERG issue and in vivo activity in a mood disorder model
ACS Medicinal Chemistry Letters. 2020; 11(5): 825-831. https://doi.org/10.1021/acsmedchemlett.9b00633
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Pu Q, Zhang H, Guo L, Cheng M, Doty AC, Ferguson H, et al.
Discovery of potent and orally available bicyclo[1.1.1]pentane-derived indoleamine-2,3-dioxygenase 1 (IDO1) inhibitors
ACS Medicinal Chemistry Letters. 2020; 11(8): 1548-1554. https://doi.org/10.1021/acsmedchemlett.0c00195
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Rai A, Bleimling N, Vetter IR, Goody RS
The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members
Nature Communications. 2020; 11(1): 4187 (16 pp.). https://doi.org/10.1038/s41467-020-17792-3
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Rondelet A, Lin Y-C, Singh D, Porfetye AT, Thakur HC, Hecker A, et al.
Clathrin's adaptor interaction sites are repurposed to stabilize microtubules during mitosis
Journal of Cell Biology. 2020; 219(2): e201907083 (29 pp.). https://doi.org/10.1083/jcb.201907083
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Rübbelke M, Fiegen D, Bauer M, Binder F, Hamilton J, King J, et al.
Locking mixed-lineage kinase domain-like protein in its auto-inhibited state prevents necroptosis
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2020; 117(52): 33272-33281. https://doi.org/10.1073/pnas.2017406117
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Schmitz RA, Dietl A, Müller M, Berben T, Op Den Camp HJM, Barends TRM
Structure of the 4-hydroxy-tetrahydrodipicolinate synthase from the thermoacidophilic methanotroph Methylacidiphilum fumariolicum SolV and the phylogeny of the aminotransferase pathway
Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 2020; 76: 199-208. https://doi.org/10.1107/S2053230X20005294
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Selim KA, Tremiño L, Marco-Marín C, Alva V, Espinosa J, Contreras A, et al.
Functional and structural characterization of PII-like protein CutA does not support involvement in heavy metal tolerance and hints at a small-molecule carrying/signaling role
FEBS Journal. 2020. https://doi.org/10.1111/febs.15464
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Solomon I, Amann M, Goubier A, Arce Vargas F, Zervas D, Qing C, et al.
CD25-Treg-depleting antibodies preserving IL-2 signaling on effector T cells enhance effector activation and antitumor immunity
Nature Cancer. 2020; 1: 1153-1166. https://doi.org/10.1038/s43018-020-00133-0
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Spinck M, Neumann-Staubitz P, Ecke M, Gasper R, Neumann H
Evolved, selective erasers of distinct lysine acylations
Angewandte Chemie International Edition. 2020; 59(27): 11142-11149. https://doi.org/10.1002/anie.202002899
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Subramanian G, Vairagoundar R, Bowen SJ, Roush N, Zachary T, Javens C, et al.
Synthetic inhibitor leads of human tropomyosin receptor kinase A (hTrkA)
RSC Medicinal Chemistry. 2020; 11(3): 370-377. https://doi.org/10.1039/c9md00554d
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Tortorici MA, Beltramello M, Lempp FA, Pinto D, Dang HV, Rosen LE, et al.
Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms
Science. 2020; 370(6519): 950-957. https://doi.org/10.1126/science.abe3354
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Velcicky J, Wilcken R, Cotesta S, Janser P, Schlapbach A, Wagner T, et al.
Discovery and optimization of novel SUCNR1 inhibitors: design of zwitterionic derivatives with a salt bridge for the improvement of oral exposure
Journal of Medicinal Chemistry. 2020; 63(17): 9856-9875. https://doi.org/10.1021/acs.jmedchem.0c01020
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Wiseman B, Högbom M
Conformational changes in apolipoprotein N-acyltransferase (Lnt)
Scientific Reports. 2020; 10(1): 639 (11 pp.). https://doi.org/10.1038/s41598-020-57419-7
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Zyla D, Echeverria B, Glockshuber R
Donor strand sequence, rather than donor strand orientation, determines the stability and non-equilibrium folding of the type 1 pilus subunit FimA
Journal of Biological Chemistry. 2020; 295(35): 12437-12448. https://doi.org/10.1074/jbc.ra120.014324
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Adlakha J, Karamichali I, Sangwallek J, Deiss S, Bär K, Coles M, et al.
Characterization of MCU-binding proteins MCUR1 and CCDC90B — representatives of a protein family conserved in prokaryotes and eukaryotic organelles
Structure. 2019; 27(3): 464-475.e6. https://doi.org/10.1016/j.str.2018.11.004
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Afanasieva E, Chaudhuri I, Martin J, Hertle E, Ursinus A, Alva V, et al.
Structural diversity of oligomeric β-propellers with different numbers of identical blades
eLife. 2019; 8: e49853 (15 pp.). https://doi.org/10.7554/eLife.49853
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Akram M, Dietl A, Mersdorf U, Prinz S, Maalcke W, Keltjens J, et al.
A 192-heme electron transfer network in the hydrazine dehydrogenase complex
Science Advances. 2019; 5(4): eaav4310 (7 pp.). https://doi.org/10.1126/sciadv.aav4310
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Akram M, Reimann J, Dietl A, Menzel A, Versantvoort W, Kartal B, et al.
A nitric oxide-binding heterodimeric cytochrome c complex from the anammox bacterium Kuenenia stuttgartiensis binds to hydrazine synthase
Journal of Biological Chemistry. 2019; 294(45): 16712-16728. https://doi.org/10.1074/jbc.RA119.008788
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Aksu M, Trakhanov S, Vera Rodriguez A, Görlich D
Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122
Journal of Cell Biology. 2019; 218(6): 1839-1852. https://doi.org/10.1083/jcb.201812093
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Apel A-K, Cheng RKY, Tautermann CS, Brauchle M, Huang C-Y, Pautsch A, et al.
Crystal structure of CC chemokine receptor 2A in complex with an orthosteric antagonist provides insights for the design of selective antagonists
Structure. 2019; 27(3): 427-438.e5. https://doi.org/10.1016/j.str.2018.10.027
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Bartolini D, Bührmann M, Barreca ML, Manfroni G, Cecchetti V, Rauh D, et al.
Co-crystal structure determination and cellular evaluation of 1,4-dihydropyrazolo[4,3-c] [1,2] benzothiazine 5,5-dioxide p38α MAPK inhibitors
Biochemical and Biophysical Research Communications. 2019; 511(3): 579-586. https://doi.org/10.1016/j.bbrc.2019.02.063
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Basu S, Kaminski JW, Panepucci E, Huang C-Y, Warshamanage R, Wang M, et al.
Automated data collection and real-time data analysis suite for serial synchrotron crystallography
Journal of Synchrotron Radiation. 2019; 26(1): 244-252. https://doi.org/10.1107/S1600577518016570
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Bokhovchuk F, Mesrouze Y, Izaac A, Meyerhofer M, Zimmermann C, Fontana P, et al.
Molecular and structural characterization of a TEAD mutation at the origin of Sveinsson's chorioretinal atrophy
FEBS Journal. 2019; 286(12): 2381-2398. https://doi.org/10.1111/febs.14817
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Brünle S, Eisinger ML, Poppe J, Mills DJ, Langer JD, Vonck J, et al.
Molybdate pumping into the molybdenum storage protein via an ATP-powered piercing mechanism
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2019; 116(52): 26497-26504. https://doi.org/10.1073/pnas.1913031116
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Chaikuad A, Thangaratnarajah C, von Delft F, Bullock AN
Structural consequences of BMPR2 kinase domain mutations causing pulmonary arterial hypertension
Scientific Reports. 2019; 9(1): 18351 (10 pp.). https://doi.org/10.1038/s41598-019-54830-7
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Chen Y, Cramer P
Structure of the super-elongation complex subunit AFF4 C-terminal homology domain reveals requirements for AFF homo-and heterodimerization
Journal of Biological Chemistry. 2019; 294(27): 10663-10673. https://doi.org/10.1074/jbc.RA119.008577
DORA PSI -
Claus C, Ferrara C, Xu W, Sam J, Lang S, Uhlenbrock F, et al.
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