Publications

Recent publications are listed below. For an extensive overview we kindly refer you to our publication repository DORA

  • André C, Martiel I, Wolff P, Landolfo M, Lorber B, Silva da Veiga C, et al.
    Interaction of a model peptide on gram negative and gram positive bacterial sliding clamps
    ACS Infectious Diseases. 2019; 5: 1022-1034. https://doi.org/10.1021/acsinfecdis.9b00089
    DORA PSI
  • Apel A-K, Cheng RKY, Tautermann CS, Brauchle M, Huang C-Y, Pautsch A, et al.
    Crystal structure of CC chemokine receptor 2A in complex with an orthosteric antagonist provides insights for the design of selective antagonists
    Structure. 2019; 27(3): 427-438.e5. https://doi.org/10.1016/j.str.2018.10.027
    DORA PSI
  • Basu S, Kaminski JW, Panepucci E, Huang C-Y, Warshamanage R, Wang M, et al.
    Automated data collection and real-time data analysis suite for serial synchrotron crystallography
    Journal of Synchrotron Radiation. 2019; 26(1): 244-252. https://doi.org/10.1107/S1600577518016570
    DORA PSI
  • Basu S, Olieric V, Leonarski F, Matsugaki N, Kawano Y, Takashi T, et al.
    Long-wavelength native-SAD phasing: opportunities and challenges
    IUCrJ. 2019; 6(3): 1-14. https://doi.org/10.1107/S2052252519002756
    DORA PSI
  • Basu S, Finke A, Vera L, Wang M, Olieric V
    Making routine native SAD a reality: lessons from beamline X06DA at the Swiss Light Source
    Acta Crystallographica Section D: Structural Biology. 2019; 75(3): 262-271. https://doi.org/10.1107/S2059798319003103
    DORA PSI
  • Galuskin EV, Krüger B, Galuskina IO, Krüger H, Vapnik Y, Pauluhn A, et al.
    Levantite, KCa3(Al2Si3)O11(PO4), a new latiumite group mineral from pyrometamorphic rock of the Hatrurim Basin, Negev Desert, Israel
    Mineralogical Magazine. 2019. https://doi.org/10.1180/mgm.2019.37
    DORA PSI
  • Kahlenberg V, Schmidmair D, Krüger H, Krüger B, Pauluhn A
    Structural studies on Ca3Al4MgO10 (C3A2M) - a ternary phase in the system CaO-Al2O3-MgO
    Journal of the American Ceramic Society. 2019; 102: 2084. https://doi.org/10.1111/jace.16001
    DORA PSI
  • Li H, Huang C-Y, Govorunova EG, Schafer CT, Sineshchekov OA, Wang M, et al.
    Crystal structure of a natural light-gated anion channelrhodopsin
    eLife. 2019; 8: e41741 (21 pp.). https://doi.org/10.7554/eLife.41741
    DORA PSI
  • Liu X, An T, Li D, Fan Z, Xiang P, Li C, et al.
    Structure of the heterophilic interaction between the nectin-like 4 and nectin-like 1 molecules
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2019; 116(6): 2068-2077. https://doi.org/10.1073/pnas.1810969116
    DORA PSI
  • Makita M, Vartiainen I, Mohacsi I, Caleman C, Diaz A, Jönsson HO, et al.
    Femtosecond phase-transition in hard x-ray excited bismuth
    Scientific Reports. 2019; 9(1): 602 (7 pp.). https://doi.org/10.1038/s41598-018-36216-3
    DORA PSI
  • Martiel I, Müller-Werkmeister HM, Cohen AE
    Strategies for sample delivery for femtosecond crystallography
    Acta Crystallographica Section D: Structural Biology. 2019; 75(2): 160-177. https://doi.org/10.1107/S2059798318017953
    DORA PSI
  • Tomizaki T, Shinoda A, Tsujino S
    Single crystal time-lapse measurement using ultrasonic acoustic levitation
    In: Gwo S, Chuang T-H, Lee Y-C, Chainani AA, Chuang Y-C, Wang C-C, et al., eds. PROCEEDINGS OF THE 13TH INTERNATIONAL CONFERENCE ON SYNCHROTRON RADIATION INSTRUMENTATION – SRI2018. Vol. 2054. AIP conference proceedings. American Institute of Physics Inc.; 2019. https://doi.org/10.1063/1.5084703
    DORA PSI
  • Tsujino S, Shinoda A, Tomizaki T
    On-demand droplet loading of ultrasonic acoustic levitator and its application for protein crystallography experiments
    Applied Physics Letters. 2019; 114(21): 213702 (5 pp.). https://doi.org/10.1063/1.5095574
    DORA PSI
  • de Wijn R, Hennig O, Roche J, Engilberge S, Rollet K, Fernandez-Millan P, et al.
    A simple and versatile microfluidic device for efficient biomacromolecule crystallization and structural analysis by serial crystallography
    IUCrJ. 2019; 6(3): 454-464. https://doi.org/10.1107/S2052252519003622
    DORA PSI
  • Aher A, Kok M, Sharma A, Rai A, Olieric N, Rodriguez-Garcia R, et al.
    CLASP Suppresses Microtubule Catastrophes through a Single TOG Domain
    Developmental Cell. 2018; 46(1): 40-58. https://doi.org/10.1016/j.devcel.2018.05.032
    DORA PSI
  • El Ghachi M, Howe N, Huang C-Y, Olieric V, Warshamanage R, Touzé T, et al.
    Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis
    Nature Communications. 2018; 9(1): 1078 (13 pp.). https://doi.org/10.1038/s41467-018-03477-5
    DORA PSI
  • Galuskin EV, Krüger B, Galuskina IO, Krüger H, Vapnik Y, Wojdyla JA, et al.
    New mineral with modular structure derived from hatruritefrom the pyrometamorphic rocks of the hatrurim complex: Ariegilatite, BaCa12(SiO4)4(PO4)2F2O, from Negev desert, Israel
    Minerals. 2018; 8(3): 109. https://doi.org/10.3390/min8030109
    DORA PSI
  • Galuskin EV, Krüger B, Galuskina IO, Krüger H, Vapnik Y, Pauluhn A, et al.
    Stracherite, BaCa6(SiO4)2[(PO4)(CO3)]F, the first CO3-bearing intercalated hexagonal antiperovskite from Negev Desert, Israel
    American Mineralogist. 2018; 103(10): 1699-1706. https://doi.org/10.2138/am-2018-6493
    DORA PSI
  • Gao X, Mu Z, Yu X, Qin B, Wojdyla J, Wang M, et al.
    Structural insight into conformational changes induced by ATP binding in a type III secretion-associated ATPase from Shigella flexneri
    Frontiers in Microbiology. 2018; 9(JUL): 1468. https://doi.org/10.3389/fmicb.2018.01468
    DORA PSI
  • Horrell S, Kekilli D, Sen K, Owen RL, Dworkowski FSN, Antonyuk SV, et al.
    Enzyme catalysis captured using multiple structures from one crystal at varying temperatures
    IUCrJ. 2018; 5: 283-292. https://doi.org/10.1107/S205225251800386X
    DORA PSI
  • Huang C-Y, Olieric V, Howe N, Warshamanage R, Weinert T, Panepucci E, et al.
    In situ serial crystallography for rapid de novo membrane protein structure determination.
    Communications Biology. 2018; 1: 124 (8 pp.). https://doi.org/10.1038/S42003-018-0123-6
    DORA PSI
  • Juroszek R, Krüger H, Galuskina I, Krüger B, Jeżak L, Ternes B, et al.
    Sharyginite, Ca3TiFe2O8a new mineral from the Bellerberg volcano, Germany
    Minerals. 2018; 8(7): 308. https://doi.org/10.3390/min8070308
    DORA PSI
  • Kahlenberg V, Galuskina I, Krüger B, Pauluhn A, Galuskin E
    Structural investigations on bredigite from the Hatrurim Complex
    Mineralogy and Petrology. 2018. https://doi.org/10.1007/s00710-018-0646-z
    DORA PSI
  • Krüger B, Krüger H, Galuskin EV, Galuskina IO, Vapnik Y, Olieric V, et al.
    Aravaite, Ba2Ca18(SiO4)6(PO4)3(CO3)F3O: modular structure and disorder of a new mineral with single and triple antiperovskite layers
    Acta Crystallographica Section B: Structural Science, Crystal Engineering and Materials. 2018; 74(6): 492-501. https://doi.org/10.1107/S2052520618012271
    DORA PSI
  • Küssau T, Flipo M, Van Wyk N, Viljoen A, Olieric V, Kremer L, et al.
    Structural rearrangements occurring upon cofactor binding in the Mycobacterium smegmatis β-ketoacyl-acyl carrier protein reductase MabA
    Acta Crystallographica Section D: Structural Biology. 2018; D74(Part 5): 383-393. https://doi.org/10.1107/S2059798318002917
    DORA PSI
  • Lebugle M, Dworkowski F, Pauluhn A, Guzenko VA, Romano L, Meier N, et al.
    High-intensity x-ray microbeam for macromolecular crystallography using silicon kinoform diffractive lenses
    Applied Optics. 2018; 57(30): 9032-9039. https://doi.org/10.1364/AO.57.009032
    DORA PSI
  • Leonarski F, Redford S, Mozzanica A, Lopez-Cuenca C, Panepucci E, Nass K, et al.
    Fast and accurate data collection for macromolecular crystallography using the JUNGFRAU detector
    Nature Methods. 2018; 15(10): 799-804. https://doi.org/10.1038/s41592-018-0143-7
    DORA PSI
  • Martiel I, Olieric V, Caffrey M, Wang M
    Practical approaches for in situ X-ray crystallography: from high-throughput screening to serial data collection
    In: Beis K, Evans G, eds. Protein crystallography: challenges and practical solutions. Chemical biology. Cambridge: Royal Society of Chemistry; 2018. https://doi.org/10.1039/9781788010504-00001
    DORA PSI
  • Mozzanica A, Andrä M, Barten R, Bergamaschi A, Chiriotti S, Brückner M, et al.
    The JUNGFRAU detector for applications at synchrotron light sources and XFELs
    Synchrotron Radiat. News. 2018:16-20.
    DORA PSI
  • Nogly P, Weinert T, James D, Carbajo S, Ozerov D, Furrer A, et al.
    Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser
    Science. 2018; 361(6398): eaat0094. https://doi.org/10.1126/science.aat0094
    DORA PSI
  • Opara NL, Mohacsi I, Makita M, Castano-Diez D, Diaz A, Juranić P, et al.
    Demonstration of femtosecond X-ray pump X-ray probe diffraction on protein crystals
    Structural Dynamics. 2018; 5(5): 054303 (15 pp.). https://doi.org/10.1063/1.5050618
    DORA PSI
  • Pande K, Donatelli JJ, Malmerberg E, Foucar L, Poon BK, Sutter M, et al.
    Free-electron laser data for multiple-particle fluctuation scattering analysis
    Scientific Data. 2018; 5: 180201. https://doi.org/10.1038/sdata.2018.201
    DORA PSI
  • Redford S, Andrä M, Barten R, Bergamaschi A, Brückner M, Chiriotti S, et al.
    Operation and performance of the JUNGFRAU photon detector during first FEL and synchrotron experiments
    Journal of Instrumentation. 2018; 13(11): C11006 (9 pp.). https://doi.org/10.1088/1748-0221/13/11/C11006
    DORA PSI
  • Scietti L, Chiapparino A, De Giorgi F, Fumagalli M, Khoriauli L, Nergadze S, et al.
    Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3
    Nature Communications. 2018; 9(1): 3163. https://doi.org/10.1038/s41467-018-05631-5
    DORA PSI
  • Sommer R, Makshakova ON, Wohlschlager T, Hutin S, Marsh M, Titz A, et al.
    Crystal structures of fungal tectonin in complex with O-methylated glycans suggest key role in innate immune defense
    Structure. 2018; 26(3): 391-402. https://doi.org/10.1016/j.str.2018.01.003
    DORA PSI
  • Wang W, Qin B, Wojdyla JA, Wang M, Gao X, Cui S
    Structural characterization of free-state and product-state Mycobacterium tuberculosis methionyl-tRNA synthetase reveals an induced-fit ligand-recognition mechanism
    IUCrJ. 2018; 5: 478-490. https://doi.org/10.1107/S2052252518008217
    DORA PSI
  • Wojdyla JA, Kaminski JW, Panepucci E, Ebner S, Wang X, Gabadinho J, et al.
    DA+ data acquisition and analysis software at the Swiss Light Source macromolecular crystallography beamlines
    Journal of Synchrotron Radiation. 2018; 25(1): 293-303. https://doi.org/10.1107/S1600577517014503
    DORA PSI
  • Yin W, Zhou XE, Yang D, de Waal PW, Wang M, Dai A, et al.
    Crystal structure of the human 5-HT1B serotonin receptor bound to an inverse agonist
    Cell Discovery. 2018; 4: 12 (13 pp.). https://doi.org/10.1038/s41421-018-0009-2
    DORA PSI
  • Zabara A, Chong JTY, Martiel I, Stark L, Cromer BA, Speziale C, et al.
    Design of ultra-swollen lipidic mesophases for the crystallization of membrane proteins with large extracellular domains
    Nature Communications. 2018; 9(1): 544. https://doi.org/10.1038/s41467-018-02996-5
    DORA PSI
  • Gati C, Oberthuer D, Yefanov O, Bunker RD, Stellato F, Chiu E, et al.
    Atomic structure of granulin determined from native nanocrystalline granulovirus using an X-ray free-electron laser
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2017; 114(9): 2247-2252. https://doi.org/10.1073/pnas.1609243114
    DORA PSI
  • Guan H, Tian J, Qin B, Wojdyla JA, Wang B, Zhao Z, et al.
    Crystal structure of 2C helicase from enterovirus 71
    Science Advances. 2017; 3(4). https://doi.org/10.1126/sciadv.1602573
    DORA PSI
  • Hao W, Wojdyla JA, Zhao R, Han R, Das R, Zlatev I, et al.
    Crystal structure of Middle East respiratory syndrome coronavirus helicase
    PLoS Pathogens. 2017; 13(6): e1006474. https://doi.org/10.1371/journal.ppat.1006474
    DORA PSI
  • Kekilli D, Petersen CA, Pixton DA, Ghafoor DD, Abdullah GH, Dworkowski FSN, et al.
    Engineering proximal vs. distal heme-NO coordination via dinitrosyl dynamics: implications for NO sensor design
    Chemical Science. 2017; 8(3): 1986-1994. https://doi.org/10.1039/c6sc04190f
    DORA PSI
  • Kekilli D, Moreno-Chicano T, Chaplin AK, Horrell S, Dworkowski FSN, Worrall JAR, et al.
    Photoreduction and validation of haem-ligand intermediate states in protein crystals by in situ single-crystal spectroscopy and diffraction
    IUCrJ. 2017; 4: 263-270. https://doi.org/10.1107/S2052252517002159
    DORA PSI
  • Kenel C, Grolimund D, Li X, Panepucci E, Samson VA, Sanchez DF, et al.
    In situ investigation of phase transformations in Ti-6Al-4V under additive manufacturing conditions combining laser melting and high-speed micro-X-ray diffraction
    Scientific Reports. 2017; 7(1): 16358. https://doi.org/10.1038/s41598-017-16760-0
    DORA PSI
  • Krüger B, Krüger H, Pauluhn A, Olieric V
    Zoharite, IMA2017-049, in CNMNC Newsletter No. 39
    Mineralogical Magazine. 2017; 81: 1281.
    DORA PSI
  • Milne CJ, Schietinger T, Aiba M, Alarcon A, Alex J, Anghel A, et al.
    SwissFEL: the Swiss X-ray free electron laser
    Applied Sciences. 2017; 7(7): 720 (57 pp.). https://doi.org/10.3390/app7070720
    DORA PSI
  • Nöll A, Thomas C, Herbring V, Zollmann T, Barth K, Mehdipour AR, et al.
    Crystal structure and mechanistic basis of a functional homolog of the antigen transporter TAP
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2017; 114(4): E438-E447. https://doi.org/10.1073/pnas.1620009114
    DORA PSI
  • Opara N, Martiel I, Arnold SA, Braun T, Stahlberg H, Makita M, et al.
    Direct protein crystallization on ultrathin membranes for diffraction measurements at X-ray free-electron lasers
    Journal of Applied Crystallography. 2017; 50(3): 909-918. https://doi.org/10.1107/S1600576717005799
    DORA PSI
  • Ou X, Guan H, Qin B, Mu Z, Wojdyla JA, Wang M, et al.
    Crystal structure of the receptor binding domain of the spike glycoprotein of human betacoronavirus HKU1
    Nature Communications. 2017; 8: 15216. https://doi.org/10.1038/ncomms15216
    DORA PSI
  • Peng G, McEwen AG, Olieric V, Schmitt C, Albrecht S, Cavarelli J, et al.
    Insight into the remarkable affinity and selectivity of the aminobenzosuberone scaffold for the M1 aminopeptidases family based on structure analysis
    Proteins. 2017; 85(8): 1413-1421. https://doi.org/10.1002/prot.25301
    DORA PSI
  • Vercellino I, Rezabkova L, Olieric V, Polyhach Y, Weinert T, Kammerer RA, et al.
    Role of the nucleotidyl cyclase helical domain in catalytically active dimer formation
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2017; 114(46): E9821-E9828. https://doi.org/10.1073/pnas.1712621114
    DORA PSI
  • Weinert T, Olieric N, Cheng R, Brünle S, James D, Ozerov D, et al.
    Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons
    Nature Communications. 2017; 8(1): 542 (11 pp.). https://doi.org/10.1038/s41467-017-00630-4
    DORA PSI
  • Wiktor MI, Weichert D, Howe N, Huang C-Y, Olieric V, Boland C, et al.
    Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis
    Nature Communications. 2017; 8: 15952. https://doi.org/10.1038/ncomms15952
    DORA PSI
  • Bheemireddy SR, Ubaldo PC, Finke AD, Wang L, Plunkett KN
    Contorted aromatics: Via a palladium-catalyzed cyclopentannulation strategy
    Journal of Materials Chemistry C. 2016; 4(18): 3963-3969. https://doi.org/10.1039/c5tc02305j
    DORA PSI
  • Bianchi S, Van Riel WE, Kraatz SHW, Olieric N, Frey D, Katrukha EA, et al.
    Structural basis for misregulation of kinesin KIF21A autoinhibition by CFEOM1 disease mutations
    Scientific Reports. 2016; 6: 30668. https://doi.org/10.1038/srep30668
    DORA PSI
  • Casanas A, Warshamanage R, Finke AD, Panepucci E, Olieric V, Nöll A, et al.
    EIGER detector: Application in macromolecular crystallography:
    Acta Crystallographica Section D: Structural Biology. 2016; 72(9): 1036-1048. https://doi.org/10.1107/S2059798316012304
    DORA PSI
  • Chatterjee A, Mallin H, Klehr J, Vallapurackal J, Finke AD, Vera L, et al.
    An enantioselective artificial Suzukiase based on the biotin-streptavidin technology
    Chemical Science. 2016; 7(1): 673-677. https://doi.org/10.1039/c5sc03116h
    DORA PSI
  • Finke AD, Panepucci E, Vonrhein C, Wang M, Bricogne G, Oliéric V
    Advanced crystallographic data collection protocols for experimental phasing
    In: Ennifar E, ed. Nucleic acid crystallography. Methods and protocols. Methods in molecular biology. New York: Humana Press; 2016. https://doi.org/10.1007%2F978-1-4939-2763-0_11
    DORA PSI
  • Howard EI, Guillot B, Blakeley MP, Haertlein M, Moulin M, Mitschler A, et al.
    High-resolution neutron and X-ray diffraction room-temperature studies of an H-FABP-oleic acid complex: Study of the internal water cluster and ligand binding by a transferred multipolar electron-density distribution
    IUCrJ. 2016; 3: 115-126. https://doi.org/10.1107/S2052252515024161
    DORA PSI
  • Huang C-Y, Olieric V, Ma P, Howe N, Vogeley L, Liu X, et al.
    In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures
    Acta Crystallographica Section D: Structural Biology. 2016; 72(1): 93-112. https://doi.org/10.1107/S2059798315021683
    DORA PSI
  • Jaeger K, Dworkowski F, Nogly P, Milne C, Wang M, Standfuss J
    Serial millisecond crystallography of membrane proteins
    In: Moraes I, ed. The next generation in membrane protein structure determination. Advances in experimental medicine and biology. Cham: Springer; 2016. https://doi.org/10.1007/978-3-319-35072-1_10
    DORA PSI
  • Lampart S, Roch LM, Dutta AK, Wang Y, Warshamanage R, Finke AD, et al.
    Pentaindenocorannulene: Properties, Assemblies, and C60Complex
    Angewandte Chemie International Edition. 2016; 55(47): 14648-14652. https://doi.org/10.1002/anie.201608337
    DORA PSI
  • Mallinger A, Schiemann K, Rink C, Sejberg J, Honey MA, Czodrowski P, et al.
    2,8-Disubstituted-1,6-Naphthyridines and 4,6-Disubstituted-Isoquinolines with Potent, Selective Affinity for CDK8/19
    ACS Medicinal Chemistry Letters. 2016; 7(6): 573-578. https://doi.org/10.1021/acsmedchemlett.6b00022
    DORA PSI
  • Marsh ME, Scott DE, Ehebauer MT, Abell C, Blundell TL, Hyvönen M
    ATP half-sites in RadA and RAD51 recombinases bind nucleotides
    FEBS Open Bio. 2016; 6(5): 372-385. https://doi.org/10.1002/2211-5463.12052
    DORA PSI
  • Olieric V, Weinert T, Finke AD, Anders C, Li D, Olieric N, et al.
    Data-collection strategy for challenging native SAD phasing
    Acta Crystallographica Section D: Structural Biology. 2016; 72(3): 421-429. https://doi.org/10.1107/S2059798315024110
    DORA PSI
  • Orts J, Wälti MA, Marsh M, Vera L, Gossert AD, Güntert P, et al.
    NMR-based determination of the 3D structure of the ligand-protein interaction site without protein resonance assignment
    Journal of the American Chemical Society. 2016; 138(13): 4393-4400. https://doi.org/10.1021/jacs.5b12391
    DORA PSI
  • Schaffer MF, Peng G, Spingler B, Schnabl J, Wang M, Olieric V, et al.
    The x-ray structures of six octameric RNA duplexes in the presence of different di- and trivalent cations
    International Journal of Molecular Sciences. 2016; 17(7): 988. https://doi.org/10.3390/ijms17070988
    DORA PSI
  • Scott DE, Marsh M, Blundell TL, Abell C, Hyvönen M
    Structure-activity relationship of the peptide binding-motif mediating the BRCA2:RAD51 protein-protein interaction
    FEBS Letters. 2016; 590(8): 1094-1102. https://doi.org/10.1002/1873-3468.12139
    DORA PSI
  • Sumy DP, Finke AD, Whalley AC
    The reductive aromatization of tridecacyclene
    Chemical Communications. 2016; 52(83): 12368-12371. https://doi.org/10.1039/c6cc06078a
    DORA PSI
  • Sumy DP, Dodge NJ, Harrison CM, Finke AD, Whalley AC
    Tridecacyclene: A Cyclic Tetramer of Acenaphthylene
    Chemistry: A European Journal. 2016; 22(14): 4709-4712. https://doi.org/10.1002/chem.201600165
    DORA PSI
  • Tong S, Lin Y, Lu S, Wang M, Bogdanov M, Zheng L
    Structural insight into substrate selection and catalysis of lipid phosphate phosphatase PgpB in the cell membrane
    Journal of Biological Chemistry. 2016; 291(35): 18342-18352. https://doi.org/10.1074/jbc.M116.737874
    DORA PSI
  • Tsujino S, Tomizaki T
    Ultrasonic acoustic levitation for fast frame rate X-ray protein crystallography at room temperature
    Scientific Reports. 2016; 6: 25558. https://doi.org/10.1038/srep25558
    DORA PSI
  • Wojdyla JA, Panepucci E, Martiel I, Ebner S, Huang C-Y, Caffrey M, et al.
    Fast two-dimensional grid and transmission X-ray microscopy scanning methods for visualizing and characterizing protein crystals
    Journal of Applied Crystallography. 2016; 49: 944-952. https://doi.org/10.1107/S1600576716006233
    DORA PSI
  • Zhou XE, Gao X, Barty A, Kang Y, He Y, Liu W, et al.
    X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex
    Scientific Data. 2016; 3: 201621. https://doi.org/10.1038/sdata.2016.21
    DORA PSI
  • Bheemireddy SR, Ubaldo PC, Rose PW, Finke AD, Zhuang J, Wang L, et al.
    Stabilizing Pentacene by Cyclopentannulation
    Angewandte Chemie International Edition. 2015; 54(52): 15762-15766. https://doi.org/10.1002/anie.201508650
    DORA PSI
  • Botha S, Nass K, Barends T, Kabsch W, Latz B, Dworkowski F, et al.
    Room-temperature serial crystallography at synchrotron X-ray sources using slowly flowing free-standing high-viscosity microstreams
    Acta Crystallographica Section D: Structural Biology. 2015; 71: 387-397. https://doi.org/10.1107/S1399004714026327
    DORA PSI
  • Chang S, Sun D, Liang H, Wang J, Li J, Guo L, et al.
    Cryo-EM Structure of Influenza Virus RNA Polymerase Complex at 4.3Å Resolution
    Molecular Cell. 2015; 57(5): 925-935. https://doi.org/10.1016/j.molcel.2014.12.031
    DORA PSI
  • Chiu E, Hijnen M, Bunker R, Boudes M, Rajendran C, Olieric V, et al.
    Structural basis for the enhancement of virulence by viral spindles and their in vivo crystallization
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2015; 112(13): 3973-3978. https://doi.org/10.1073/pnas.1418798112
    DORA PSI
  • Demurtas D, Guichard P, Martiel I, Mezzenga R, Hébert C, Sagalowicz L
    Direct visualization of dispersed lipid bicontinuous cubic phases by cryo-electron tomography
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  • Koch M, Chitayat S, Dattilo BM, Schiefner A, Diez J, Chazin WJ, et al.
    Structural Basis for Ligand Recognition and Activation of RAGE
    Structure. 2010; 18(10): 1342-1352. https://doi.org/10.1016/j.str.2010.05.017
    DORA PSI
  • Lack NA, Yam KC, Lowe EE, Horsman GP, Owen RL, Sim E, et al.
    Characterization of a carbon-carbon hydrolase from Mycobacterium tuberculosis involved in cholesterol metabolism
    Journal of Biological Chemistry. 2010; 285(1): 434-443. https://doi.org/10.1074/jbc.M109.058081
    DORA PSI
  • Lanz VA, Pŕev̂ot ASH, Alfarra MR, Weimer S, Mohr C, Decarlo PF, et al.
    Characterization of aerosol chemical composition with aerosol mass spectrometry in Central Europe: An overview
    Atmospheric Chemistry and Physics. 2010; 10(21): 10453-10471. https://doi.org/10.5194/acp-10-10453-2010
    DORA PSI
  • Oberti S, Möller D, Neild A, Dual J, Beyeler F, Nelson BJ, et al.
    Strategies for single particle manipulation using acoustic and flow fields
    Ultrasonics. 2010; 50(2): 247-257. https://doi.org/10.1016/j.ultras.2009.09.004
    DORA PSI
  • Quaroni L, Schneider J, Armstrong D, Wambach J, Lerch P
    The Infrared Beamline at the Swiss Light Source: a Tool for Chemical Microanalysis
    Chimia. 2010; 64.
    DORA PSI
  • Truan D, Huergo LF, Chubatsu LS, Merrick M, Li X-D, Winkler FK
    A new PII protein structure identifies the 2-oxoglutarate binding site
    Journal of Molecular Biology. 2010; 400(3): 531-539. https://doi.org/10.1016/j.jmb.2010.05.036
    DORA PSI
  • Waltersperger S, Widmer C, Wang M, Baumann U
    Crystal structure of archaemetzincin AmzA from methanopyrus kandleri at 1.5 Å resolution
    Proteins. 2010; 78(12): 2720-2723. https://doi.org/10.1002/prot.22777
    DORA PSI
  • Wang M
    Crystal Structures of Progressive Ca2+ Binding States of the Ca2+ Sensor CBD1 from the CALX Na+/Ca2+ Exchanger Reveal Incremental Conformational Transitions
    Journal of Biological Chemistry. 2010; 285. https://doi.org/10.1074/jbc.M109.059162
    DORA PSI
  • Yeh JI, Pohl E, Truan D, He W, Sheldrick GM, Du S, et al.
    The crystal structure of non-modified and bipyridine-modified PNA duplexes
    Chemistry: A European Journal. 2010; 16(39): 11867-11875. https://doi.org/10.1002/chem.201000392
    DORA PSI
  • Bullock AN, Russo S, Amos A, Pagano N, Bregman H, Debreczeni JÉ, et al.
    Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor
    PLoS One. 2009; 4(10): e7112. https://doi.org/10.1371/journal.pone.0007112
    DORA PSI
  • Coulibaly F, Chiu E, Gutmann S, Rajendran C, Haebel PW, Ikeda K, et al.
    The atomic structure of baculovirus polyhedra reveals the independent emergence of infectious crystals in DNA and RNA viruses
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2009; 106(52): 22205-22210. https://doi.org/10.1073/pnas.0910686106
    DORA PSI
  • Langenhan T, Prömel S, Mestek L, Esmaeili B, Waller-Evans H, Hennig C, et al.
    Latrophilin signaling links anterior-posterior tissue polarity and oriented cell divisions in the C. elegans embryo
    Developmental Cell. 2009; 17(4): 494-504. https://doi.org/10.1016/j.devcel.2009.08.008
    DORA PSI
  • Meents A, Dittrich B, Gutmann S
    A new aspect of specific radiation damage: Hydrogen abstraction from organic molecules
    Journal of Synchrotron Radiation. 2009; 16(2): 183-190. https://doi.org/10.1107/S0909049509002192
    DORA PSI
  • Mueller M, Grauschopf U, Maier T, Glockshuber R, Ban N
    The structure of a cytolytic α-helical toxin pore reveals its assembly mechanism
    Nature. 2009; 459(7247): 726-730. https://doi.org/10.1038/nature08026
    DORA PSI
  • Oberholzer AE, Bumann M, Hege T, Russo S, Baumann U
    Metzincin's canonical methionine is responsible for the structural integrity of the zinc-binding site
    Biological Chemistry. 2009; 390(9): 875-881. https://doi.org/10.1515/BC.2009.100
    DORA PSI
  • Oberti S, Möller D, Gutmann S, Neild A, Dual J
    Novel sample preparation technique for protein crystal X-ray crystallographic analysis combining microfluidics and acoustic manipulation
    Journal of Applied Crystallography. 2009; 42(4): 636-641. https://doi.org/10.1107/S0021889809019177
    DORA PSI
  • Olieric V, Rieder U, Lang K, Serganov A, Schulze-Briese C, Micura R, et al.
    A fast selenium derivatization strategy for crystallization and phasing of RNA structures
    RNA. 2009; 15(4): 707-715. https://doi.org/10.1261/rna.1499309
    DORA PSI
  • Oliéric V, Wolff P, Takeuchi A, Bec G, Birck C, Vitorino M, et al.
    SECIS-binding protein 2, a key player in selenoprotein synthesis, is an intrinsically disordered protein
    Biochimie. 2009; 91(8): 1003-1009. https://doi.org/10.1016/j.biochi.2009.05.004
    DORA PSI
  • Owen RL, Pearson AR, Meents A, Boehler P, Thominet V, Schulze-Briese C
    A new on-axis multimode spectrometer for the macromolecular crystallography beamlines of the Swiss Light Source
    Journal of Synchrotron Radiation. 2009; 16(2): 173-182. https://doi.org/10.1107/S0909049508040120
    DORA PSI
  • Owen RL, Holton JM, Schulze-Briese C, Garman EF
    Determination of X-ray flux using silicon pin diodes
    Journal of Synchrotron Radiation. 2009; 16(2): 143-151. https://doi.org/10.1107/S0909049508040429
    DORA PSI
  • Owen RL, Holton JM, Schulze-Briese C, Garman EF
    Response to Krumreys Comments on Determination of X-ray flux using silicon pin diodes by R. L. Owen et al. (2009). J. Synchrotron Rad. 16, 143-153
    Journal of Synchrotron Radiation. 2009; 16(5): 691-692. https://doi.org/10.1107/S0909049509023644
    DORA PSI
  • Russo S, Schweitzer J-E, Polen T, Bott M, Pohl E
    Crystal structure of the caseinolytic protease gene regulator, a transcriptional activator in actinomycetes
    Journal of Biological Chemistry. 2009; 284(8): 5208-5216. https://doi.org/10.1074/jbc.M806591200
    DORA PSI
  • Wagner A, Diez J, Schulze-Briese C, Schluckebier G
    Crystal structure of Ultralente - A microcrystalline insulin suspension
    Proteins. 2009; 74(4): 1018-1027. https://doi.org/10.1002/prot.22213
    DORA PSI
  • Wu M, Wang M, Nix J, Hryshko LV, Zheng L
    Crystal Structure of CBD2 from the Drosophila Na+/Ca2+ Exchanger: Diversity of Ca2+ Regulation and Its Alternative Splicing Modification
    Journal of Molecular Biology. 2009; 387(1): 104-112. https://doi.org/10.1016/j.jmb.2009.01.045
    DORA PSI
  • Yang L, Wang M, Stoeckigt J
    Structural Basis and Enzymatic Mechanism of the Biosynthesis of C9- from C10-Monoterpenoid Indole Alkaloids
    Angewandte Chemie International Edition. 2009; 48.
    DORA PSI
  • Blaise M, Olieric V, Sauter C, Lorber B, Roy B, Karmakar S, et al.
    Crystal Structure of Glutamyl-Queuosine tRNAAsp Synthetase Complexed with l-Glutamate: Structural Elements Mediating tRNA-Independent Activation of Glutamate and Glutamylation of tRNAAsp Anticodon
    Journal of Molecular Biology. 2008; 381(5): 1224-1237. https://doi.org/10.1016/j.jmb.2008.06.053
    DORA PSI
  • Felderer K, Groves M, Diez J, Pohl E, Witt S
    Crystallization and preliminary X-ray analysis of the Thermoplasma acidophilum 20S proteasome in complex with protein substrates
    Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 2008; 64(10): 899-902. https://doi.org/10.1107/S1744309108026791
    DORA PSI
  • Koch M, Diez J, Fritz G
    Crystal structure of Ca2+-free S100A2 at 1.6-Å resolution
    Journal of Molecular Biology. 2008; 378(4): 933-942. https://doi.org/10.1016/j.jmb.2008.03.019
    DORA PSI
  • Malo GD, Wang M, Wu D, Stelling AL, Tonge PJ, Wachter RM
    Crystal Structure and Raman Studies of dsFP483, a Cyan Fluorescent Protein from Discosoma striata
    Journal of Molecular Biology. 2008; 378(4): 869-884. https://doi.org/10.1016/j.jmb.2008.02.069
    DORA PSI
  • Malojčić G, Owen RL, Grimshaw JPA, Brozzo MS, Dreher-Teo H, Glockshuber R
    A structural and biochemical basis for PAPS-independent sulfuryl transfer by aryl sulfotransferase from uropathogenic Escherichia coli
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2008; 105(49): 19217-19222. https://doi.org/10.1073/pnas.0806997105
    DORA PSI
  • Malojčić G, Owen RL, Grimshaw JPA, Glockshuber R
    Preparation and structure of the charge-transfer intermediate of the transmembrane redox catalyst DsbB
    FEBS Letters. 2008; 582(23-24): 3301-3307. https://doi.org/10.1016/j.febslet.2008.07.063
    DORA PSI
  • Pauluhn A, Ahmed H, Lorentzen E, Buchinger S, Schomburg D, Siebers B, et al.
    Crystal structure and stereochemical studies of KD(P)G aldolase from Thermoproteus tenax
    Proteins. 2008; 72(1): 35-43. https://doi.org/10.1002/prot.21890
    DORA PSI
  • Steinmetz MO, Gattin Z, Verel R, Ciani B, Stromer T, Green JM, et al.
    Atomic Models of De Novo Designed ccβ-Met Amyloid-Like Fibrils
    Journal of Molecular Biology. 2008; 376(3): 898-912. https://doi.org/10.1016/j.jmb.2007.11.100
    DORA PSI
  • Varco-Merth B, Fromme R, Wang M, Fromme P
    Crystallization of the c14-rotor of the chloroplast ATP synthase reveals that it contains pigments
    Biochimica et Biophysica Acta: Bioenergetics. 2008; 1777(7-8): 605-612. https://doi.org/10.1016/j.bbabio.2008.05.009
    DORA PSI
  • Chen Q, Bächli H, Höchli C, Wullschleger R, Abela R, Ingold G, et al.
    Current status of the front ends at the SLS
    In: Synchrotron radiation instrumentation, Pts 1 and 2. Vol. 879. AIP conference proceedings. ; 2007. https://doi.org/10.1063/1.2436238
    DORA PSI
  • Coulibaly F, Chiu E, Ikeda K, Gutmann S, Haebel PW, Schulze-Briese C, et al.
    The molecular organization of cypovirus polyhedra
    Nature. 2007; 446(7131): 97-101. https://doi.org/10.1038/nature05628
    DORA PSI
  • Dhagat U, Carbone V, Chung RP-T, Schulze-Briese C, Endo S, Hara A, et al.
    Structure of 3(17)α-hydroxysteroid dehydrogenase (AKR1C21) holoenzyme from an orthorhombic crystal form: An insight into the bifunctionality of the enzyme
    Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 2007; 63(10): 825-830. https://doi.org/10.1107/S1744309107040985
    DORA PSI
  • Diez J, Wang M, Pohl E, Tomizaki T, Bertrand A, Chen Q, et al.
    Industrial use of the SLS-MX beamlines
    Synchrotron Radiation News. 2007; 20(4): 19-22. https://doi.org/10.1080/08940880701510787
    DORA PSI
  • Lucarelli D, Russo S, Garman E, Milano A, Meyer-Klaucke W, Pohl E
    Crystal structure and function of the zinc uptake regulator FurB from Mycobacterium tuberculosis
    Journal of Biological Chemistry. 2007; 282(13): 9914-9922. https://doi.org/10.1074/jbc.M609974200
    DORA PSI
  • Lupo D, Tomizaki T, Winkler FK
    The 1.3-A resolution structure of Nitrosomonas europaea Rh50 and mechanistic implications for NH3 transport by Rhesus family proteins
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2007; 104.
    DORA PSI

Associated Beamlines

Contact

Head of MX
and Group Leader (i.p.) MX Applications
Dr. Meitian Wang
Telephone:
+41 56 310 4175
E-mail:
meitian.wang@psi.ch

Group Leader MX Instrumentation
Wayne Glettig
Telephone:
+41 56 310 5823
E-mail:
wayne.glettig@psi.ch

Group Leader MX Samples
Dr. May Marsh
Telephone:
+41 56 310 5437
E-mail:
may.marsh@psi.ch