Publications

Recent publications are listed below. For an extensive overview we kindly refer you to our publication repository DORA

  • André C, Martiel I, Wolff P, Landolfo M, Lorber B, Silva da Veiga C, et al.
    Interaction of a model peptide on gram negative and gram positive bacterial sliding clamps
    ACS Infectious Diseases. 2019; 5: 1022-1034. https://doi.org/10.1021/acsinfecdis.9b00089
    DORA PSI
  • Apel A-K, Cheng RKY, Tautermann CS, Brauchle M, Huang C-Y, Pautsch A, et al.
    Crystal structure of CC chemokine receptor 2A in complex with an orthosteric antagonist provides insights for the design of selective antagonists
    Structure. 2019; 27(3): 427-438.e5. https://doi.org/10.1016/j.str.2018.10.027
    DORA PSI
  • Basu S, Kaminski JW, Panepucci E, Huang C-Y, Warshamanage R, Wang M, et al.
    Automated data collection and real-time data analysis suite for serial synchrotron crystallography
    Journal of Synchrotron Radiation. 2019; 26(1): 244-252. https://doi.org/10.1107/S1600577518016570
    DORA PSI
  • Basu S, Olieric V, Leonarski F, Matsugaki N, Kawano Y, Takashi T, et al.
    Long-wavelength native-SAD phasing: opportunities and challenges
    IUCrJ. 2019; 6(3): 1-14. https://doi.org/10.1107/S2052252519002756
    DORA PSI
  • Basu S, Finke A, Vera L, Wang M, Olieric V
    Making routine native SAD a reality: lessons from beamline X06DA at the Swiss Light Source
    Acta Crystallographica Section D: Structural Biology. 2019; 75(3): 262-271. https://doi.org/10.1107/S2059798319003103
    DORA PSI
  • Galuskin EV, Krüger B, Galuskina IO, Krüger H, Vapnik Y, Pauluhn A, et al.
    Levantite, KCa3(Al2Si3)O11(PO4), a new latiumite group mineral from pyrometamorphic rock of the Hatrurim Basin, Negev Desert, Israel
    Mineralogical Magazine. 2019; 83(5): 713-721. https://doi.org/10.1180/mgm.2019.37
    DORA PSI
  • Jensen SC, Sullivan B, Hartzler DA, Aguilar JM, Awel S, Bajt S, et al.
    X-ray emission spectroscopy at X-ray free electron lasers: limits to observation of the classical spectroscopic response for electronic structure analysis
    Journal of Physical Chemistry Letters. 2019; 10(3): 441-446. https://doi.org/10.1021/acs.jpclett.8b03595
    DORA PSI
  • Kahlenberg V, Schmidmair D, Krüger H, Krüger B, Pauluhn A
    Structural studies on Ca3Al4MgO10 (C3A2M) - a ternary phase in the system CaO-Al2O3-MgO
    Journal of the American Ceramic Society. 2019; 102: 2084. https://doi.org/10.1111/jace.16001
    DORA PSI
  • Leonarski F, D’Ascenzo L, Auffinger P
    Nucleobase carbonyl groups are poor Mg2+ inner-sphere binders but excellent monovalent ion binders - a critical PDB survey
    RNA. 2019; 25(11): 173-192. https://doi.org/10.1261/rna.068437.118
    DORA PSI
  • Li H, Huang C-Y, Govorunova EG, Schafer CT, Sineshchekov OA, Wang M, et al.
    Crystal structure of a natural light-gated anion channelrhodopsin
    eLife. 2019; 8: e41741 (21 pp.). https://doi.org/10.7554/eLife.41741
    DORA PSI
  • Liu X, An T, Li D, Fan Z, Xiang P, Li C, et al.
    Structure of the heterophilic interaction between the nectin-like 4 and nectin-like 1 molecules
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2019; 116(6): 2068-2077. https://doi.org/10.1073/pnas.1810969116
    DORA PSI
  • Makita M, Vartiainen I, Mohacsi I, Caleman C, Diaz A, Jönsson HO, et al.
    Femtosecond phase-transition in hard x-ray excited bismuth
    Scientific Reports. 2019; 9(1): 602 (7 pp.). https://doi.org/10.1038/s41598-018-36216-3
    DORA PSI
  • Martiel I, Müller-Werkmeister HM, Cohen AE
    Strategies for sample delivery for femtosecond crystallography
    Acta Crystallographica Section D: Structural Biology. 2019; 75(2): 160-177. https://doi.org/10.1107/S2059798318017953
    DORA PSI
  • Meyer M, Walbott H, Oliéric V, Kondo J, Costa M, Masquida B
    Conformational adaptation of UNCG loops upon crowding
    RNA. 2019; 25(11): 1522-1531. https://doi.org/10.1261/rna.072694.119
    DORA PSI
  • Tomizaki T, Shinoda A, Tsujino S
    Single crystal time-lapse measurement using ultrasonic acoustic levitation
    In: Gwo S, Huang D-J, Wei D-H, eds. Proceedings of the 13th international conference on synchrotron radiation instrumentation – SRI2018. Vol. 2054. AIP conference proceedings. Melville, New York: AIP Publishing; 2019. https://doi.org/10.1063/1.5084703
    DORA PSI
  • Tsujino S, Shinoda A, Tomizaki T
    On-demand droplet loading of ultrasonic acoustic levitator and its application for protein crystallography experiments
    Applied Physics Letters. 2019; 114(21): 213702 (5 pp.). https://doi.org/10.1063/1.5095574
    DORA PSI
  • Tsujino S, Sato Y, Takeda Y, Tomizaki T
    Oscillation resonances and anisotropic damping of the motion of acoustically levitated droplets in single-axis acoustic levitators
    Applied Physics Letters. 2019; 115: 053702 (5 pp.). https://doi.org/10.1063/1.5112109
    DORA PSI
  • Ung KL, Alsarraf HMAB, Olieric V, Kremer L, Blaise M
    Crystal structure of the aminoglycosides N‐acetyltransferase Eis2 from Mycobacterium abscessus
    FEBS Journal. 2019; 286(21): 4342-4355. https://doi.org/10.1111/febs.14975
    DORA PSI
  • Wang W, Yu L-J, Xu C, Tomizaki T, Zhao S, Umena Y, et al.
    Structural basis for blue-green light harvesting and energy dissipation in diatoms
    Science. 2019; 363(6427): 598 (8 pp.). https://doi.org/10.1126/science.aav0365
    DORA PSI
  • Wang N, Bosc C, Ryul Choi S, Boulan B, Peris L, Olieric N, et al.
    Structural basis of tubulin detyrosination by the vasohibin–SVBP enzyme complex
    Nature Structural and Molecular Biology. 2019; 26(7): 571-582. https://doi.org/10.1038/s41594-019-0241-y
    DORA PSI
  • Weinert T, Skopintsev P, James D, Dworkowski F, Panepucci E, Kekilli D, et al.
    Proton uptake mechanism in bacteriorhodopsin captured by serial synchrotron crystallography
    Science. 2019; 365(6448): 61-65. https://doi.org/10.1126/science.aaw8634
    DORA PSI
  • de Wijn R, Hennig O, Roche J, Engilberge S, Rollet K, Fernandez-Millan P, et al.
    A simple and versatile microfluidic device for efficient biomacromolecule crystallization and structural analysis by serial crystallography
    IUCrJ. 2019; 6(3): 454-464. https://doi.org/10.1107/S2052252519003622
    DORA PSI
  • Aher A, Kok M, Sharma A, Rai A, Olieric N, Rodriguez-Garcia R, et al.
    CLASP Suppresses Microtubule Catastrophes through a Single TOG Domain
    Developmental Cell. 2018; 46(1): 40-58. https://doi.org/10.1016/j.devcel.2018.05.032
    DORA PSI
  • El Ghachi M, Howe N, Huang C-Y, Olieric V, Warshamanage R, Touzé T, et al.
    Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis
    Nature Communications. 2018; 9(1): 1078 (13 pp.). https://doi.org/10.1038/s41467-018-03477-5
    DORA PSI
  • Galuskin EV, Krüger B, Galuskina IO, Krüger H, Vapnik Y, Wojdyla JA, et al.
    New mineral with modular structure derived from hatruritefrom the pyrometamorphic rocks of the hatrurim complex: Ariegilatite, BaCa12(SiO4)4(PO4)2F2O, from Negev desert, Israel
    Minerals. 2018; 8(3): 109. https://doi.org/10.3390/min8030109
    DORA PSI
  • Galuskin EV, Krüger B, Galuskina IO, Krüger H, Vapnik Y, Pauluhn A, et al.
    Stracherite, BaCa6(SiO4)2[(PO4)(CO3)]F, the first CO3-bearing intercalated hexagonal antiperovskite from Negev Desert, Israel
    American Mineralogist. 2018; 103(10): 1699-1706. https://doi.org/10.2138/am-2018-6493
    DORA PSI
  • Gao X, Mu Z, Yu X, Qin B, Wojdyla J, Wang M, et al.
    Structural insight into conformational changes induced by ATP binding in a type III secretion-associated ATPase from Shigella flexneri
    Frontiers in Microbiology. 2018; 9(JUL): 1468. https://doi.org/10.3389/fmicb.2018.01468
    DORA PSI
  • Horrell S, Kekilli D, Sen K, Owen RL, Dworkowski FSN, Antonyuk SV, et al.
    Enzyme catalysis captured using multiple structures from one crystal at varying temperatures
    IUCrJ. 2018; 5: 283-292. https://doi.org/10.1107/S205225251800386X
    DORA PSI
  • Huang C-Y, Olieric V, Howe N, Warshamanage R, Weinert T, Panepucci E, et al.
    In situ serial crystallography for rapid de novo membrane protein structure determination.
    Communications Biology. 2018; 1: 124 (8 pp.). https://doi.org/10.1038/S42003-018-0123-6
    DORA PSI
  • Juroszek R, Krüger H, Galuskina I, Krüger B, Jeżak L, Ternes B, et al.
    Sharyginite, Ca3TiFe2O8a new mineral from the Bellerberg volcano, Germany
    Minerals. 2018; 8(7): 308. https://doi.org/10.3390/min8070308
    DORA PSI
  • Kahlenberg V, Galuskina I, Krüger B, Pauluhn A, Galuskin E
    Structural investigations on bredigite from the Hatrurim Complex
    Mineralogy and Petrology. 2018. https://doi.org/10.1007/s00710-018-0646-z
    DORA PSI
  • Krüger B, Krüger H, Galuskin EV, Galuskina IO, Vapnik Y, Olieric V, et al.
    Aravaite, Ba2Ca18(SiO4)6(PO4)3(CO3)F3O: modular structure and disorder of a new mineral with single and triple antiperovskite layers
    Acta Crystallographica Section B: Structural Science, Crystal Engineering and Materials. 2018; 74(6): 492-501. https://doi.org/10.1107/S2052520618012271
    DORA PSI
  • Küssau T, Flipo M, Van Wyk N, Viljoen A, Olieric V, Kremer L, et al.
    Structural rearrangements occurring upon cofactor binding in the Mycobacterium smegmatis β-ketoacyl-acyl carrier protein reductase MabA
    Acta Crystallographica Section D: Structural Biology. 2018; D74(Part 5): 383-393. https://doi.org/10.1107/S2059798318002917
    DORA PSI
  • Lebugle M, Dworkowski F, Pauluhn A, Guzenko VA, Romano L, Meier N, et al.
    High-intensity x-ray microbeam for macromolecular crystallography using silicon kinoform diffractive lenses
    Applied Optics. 2018; 57(30): 9032-9039. https://doi.org/10.1364/AO.57.009032
    DORA PSI
  • Leonarski F, Redford S, Mozzanica A, Lopez-Cuenca C, Panepucci E, Nass K, et al.
    Fast and accurate data collection for macromolecular crystallography using the JUNGFRAU detector
    Nature Methods. 2018; 15(10): 799-804. https://doi.org/10.1038/s41592-018-0143-7
    DORA PSI
  • Martiel I, Olieric V, Caffrey M, Wang M
    Practical approaches for in situ X-ray crystallography: from high-throughput screening to serial data collection
    In: Beis K, Evans G, eds. Protein crystallography: challenges and practical solutions. Chemical biology. Cambridge: Royal Society of Chemistry; 2018. https://doi.org/10.1039/9781788010504-00001
    DORA PSI
  • Mozzanica A, Andrä M, Barten R, Bergamaschi A, Chiriotti S, Brückner M, et al.
    The JUNGFRAU detector for applications at synchrotron light sources and XFELs
    Synchrotron Radiation News. 2018; 31(6): 16-20. https://doi.org/10.1080/08940886.2018.1528429
    DORA PSI
  • Nogly P, Weinert T, James D, Carbajo S, Ozerov D, Furrer A, et al.
    Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser
    Science. 2018; 361(6398): eaat0094 (7 pp.). https://doi.org/10.1126/science.aat0094
    DORA PSI
  • Opara NL, Mohacsi I, Makita M, Castano-Diez D, Diaz A, Juranić P, et al.
    Demonstration of femtosecond X-ray pump X-ray probe diffraction on protein crystals
    Structural Dynamics. 2018; 5(5): 054303 (15 pp.). https://doi.org/10.1063/1.5050618
    DORA PSI
  • Pande K, Donatelli JJ, Malmerberg E, Foucar L, Poon BK, Sutter M, et al.
    Free-electron laser data for multiple-particle fluctuation scattering analysis
    Scientific Data. 2018; 5: 180201. https://doi.org/10.1038/sdata.2018.201
    DORA PSI
  • Redford S, Andrä M, Barten R, Bergamaschi A, Brückner M, Chiriotti S, et al.
    Operation and performance of the JUNGFRAU photon detector during first FEL and synchrotron experiments
    Journal of Instrumentation. 2018; 13(11): C11006 (9 pp.). https://doi.org/10.1088/1748-0221/13/11/C11006
    DORA PSI
  • Scietti L, Chiapparino A, De Giorgi F, Fumagalli M, Khoriauli L, Nergadze S, et al.
    Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3
    Nature Communications. 2018; 9(1): 3163 (11 pp.). https://doi.org/10.1038/s41467-018-05631-5
    DORA PSI
  • Sommer R, Makshakova ON, Wohlschlager T, Hutin S, Marsh M, Titz A, et al.
    Crystal structures of fungal tectonin in complex with O-methylated glycans suggest key role in innate immune defense
    Structure. 2018; 26(3): 391-402. https://doi.org/10.1016/j.str.2018.01.003
    DORA PSI
  • Vasiliauskaité-Brooks I, Healey RD, Rochaix P, Saint-Paul J, Sounier R, Grison C, et al.
    Structure of a human intramembrane ceramidase explains enzymatic dysfunction found in leukodystrophy
    Nature Communications. 2018; 9(1): 5437 (13 pp.). https://doi.org/10.1038/s41467-018-07864-w
    DORA PSI
  • Wang W, Qin B, Wojdyla JA, Wang M, Gao X, Cui S
    Structural characterization of free-state and product-state Mycobacterium tuberculosis methionyl-tRNA synthetase reveals an induced-fit ligand-recognition mechanism
    IUCrJ. 2018; 5: 478-490. https://doi.org/10.1107/S2052252518008217
    DORA PSI
  • Wojdyla JA, Kaminski JW, Panepucci E, Ebner S, Wang X, Gabadinho J, et al.
    DA+ data acquisition and analysis software at the Swiss Light Source macromolecular crystallography beamlines
    Journal of Synchrotron Radiation. 2018; 25(1): 293-303. https://doi.org/10.1107/S1600577517014503
    DORA PSI
  • Yin W, Zhou XE, Yang D, de Waal PW, Wang M, Dai A, et al.
    Crystal structure of the human 5-HT1B serotonin receptor bound to an inverse agonist
    Cell Discovery. 2018; 4: 12 (13 pp.). https://doi.org/10.1038/s41421-018-0009-2
    DORA PSI
  • Zabara A, Chong JTY, Martiel I, Stark L, Cromer BA, Speziale C, et al.
    Design of ultra-swollen lipidic mesophases for the crystallization of membrane proteins with large extracellular domains
    Nature Communications. 2018; 9(1): 544. https://doi.org/10.1038/s41467-018-02996-5
    DORA PSI
  • Gati C, Oberthuer D, Yefanov O, Bunker RD, Stellato F, Chiu E, et al.
    Atomic structure of granulin determined from native nanocrystalline granulovirus using an X-ray free-electron laser
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2017; 114(9): 2247-2252. https://doi.org/10.1073/pnas.1609243114
    DORA PSI
  • Guan H, Tian J, Qin B, Wojdyla JA, Wang B, Zhao Z, et al.
    Crystal structure of 2C helicase from enterovirus 71
    Science Advances. 2017; 3(4). https://doi.org/10.1126/sciadv.1602573
    DORA PSI
  • Hao W, Wojdyla JA, Zhao R, Han R, Das R, Zlatev I, et al.
    Crystal structure of Middle East respiratory syndrome coronavirus helicase
    PLoS Pathogens. 2017; 13(6): e1006474. https://doi.org/10.1371/journal.ppat.1006474
    DORA PSI
  • Kekilli D, Petersen CA, Pixton DA, Ghafoor DD, Abdullah GH, Dworkowski FSN, et al.
    Engineering proximal vs. distal heme-NO coordination via dinitrosyl dynamics: implications for NO sensor design
    Chemical Science. 2017; 8(3): 1986-1994. https://doi.org/10.1039/c6sc04190f
    DORA PSI
  • Kekilli D, Moreno-Chicano T, Chaplin AK, Horrell S, Dworkowski FSN, Worrall JAR, et al.
    Photoreduction and validation of haem-ligand intermediate states in protein crystals by in situ single-crystal spectroscopy and diffraction
    IUCrJ. 2017; 4: 263-270. https://doi.org/10.1107/S2052252517002159
    DORA PSI
  • Kenel C, Grolimund D, Li X, Panepucci E, Samson VA, Sanchez DF, et al.
    In situ investigation of phase transformations in Ti-6Al-4V under additive manufacturing conditions combining laser melting and high-speed micro-X-ray diffraction
    Scientific Reports. 2017; 7(1): 16358. https://doi.org/10.1038/s41598-017-16760-0
    DORA PSI
  • Milne CJ, Schietinger T, Aiba M, Alarcon A, Alex J, Anghel A, et al.
    SwissFEL: the Swiss X-ray free electron laser
    Applied Sciences. 2017; 7(7): 720 (57 pp.). https://doi.org/10.3390/app7070720
    DORA PSI
  • Nöll A, Thomas C, Herbring V, Zollmann T, Barth K, Mehdipour AR, et al.
    Crystal structure and mechanistic basis of a functional homolog of the antigen transporter TAP
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2017; 114(4): E438-E447. https://doi.org/10.1073/pnas.1620009114
    DORA PSI
  • Opara N, Martiel I, Arnold SA, Braun T, Stahlberg H, Makita M, et al.
    Direct protein crystallization on ultrathin membranes for diffraction measurements at X-ray free-electron lasers
    Journal of Applied Crystallography. 2017; 50(3): 909-918. https://doi.org/10.1107/S1600576717005799
    DORA PSI
  • Ou X, Guan H, Qin B, Mu Z, Wojdyla JA, Wang M, et al.
    Crystal structure of the receptor binding domain of the spike glycoprotein of human betacoronavirus HKU1
    Nature Communications. 2017; 8: 15216. https://doi.org/10.1038/ncomms15216
    DORA PSI
  • Peng G, McEwen AG, Olieric V, Schmitt C, Albrecht S, Cavarelli J, et al.
    Insight into the remarkable affinity and selectivity of the aminobenzosuberone scaffold for the M1 aminopeptidases family based on structure analysis
    Proteins. 2017; 85(8): 1413-1421. https://doi.org/10.1002/prot.25301
    DORA PSI
  • Vercellino I, Rezabkova L, Olieric V, Polyhach Y, Weinert T, Kammerer RA, et al.
    Role of the nucleotidyl cyclase helical domain in catalytically active dimer formation
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2017; 114(46): E9821-E9828. https://doi.org/10.1073/pnas.1712621114
    DORA PSI
  • Weinert T, Olieric N, Cheng R, Brünle S, James D, Ozerov D, et al.
    Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons
    Nature Communications. 2017; 8(1): 542 (11 pp.). https://doi.org/10.1038/s41467-017-00630-4
    DORA PSI
  • Wiktor MI, Weichert D, Howe N, Huang C-Y, Olieric V, Boland C, et al.
    Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis
    Nature Communications. 2017; 8: 15952. https://doi.org/10.1038/ncomms15952
    DORA PSI
  • Bheemireddy SR, Ubaldo PC, Finke AD, Wang L, Plunkett KN
    Contorted aromatics: Via a palladium-catalyzed cyclopentannulation strategy
    Journal of Materials Chemistry C. 2016; 4(18): 3963-3969. https://doi.org/10.1039/c5tc02305j
    DORA PSI
  • Bianchi S, Van Riel WE, Kraatz SHW, Olieric N, Frey D, Katrukha EA, et al.
    Structural basis for misregulation of kinesin KIF21A autoinhibition by CFEOM1 disease mutations
    Scientific Reports. 2016; 6: 30668. https://doi.org/10.1038/srep30668
    DORA PSI
  • Casanas A, Warshamanage R, Finke AD, Panepucci E, Olieric V, Nöll A, et al.
    EIGER detector: Application in macromolecular crystallography:
    Acta Crystallographica Section D: Structural Biology. 2016; 72(9): 1036-1048. https://doi.org/10.1107/S2059798316012304
    DORA PSI
  • Chatterjee A, Mallin H, Klehr J, Vallapurackal J, Finke AD, Vera L, et al.
    An enantioselective artificial Suzukiase based on the biotin-streptavidin technology
    Chemical Science. 2016; 7(1): 673-677. https://doi.org/10.1039/c5sc03116h
    DORA PSI
  • Finke AD, Panepucci E, Vonrhein C, Wang M, Bricogne G, Oliéric V
    Advanced crystallographic data collection protocols for experimental phasing
    In: Ennifar E, ed. Nucleic acid crystallography. Methods and protocols. Methods in molecular biology. New York: Humana Press; 2016. https://doi.org/10.1007%2F978-1-4939-2763-0_11
    DORA PSI
  • Howard EI, Guillot B, Blakeley MP, Haertlein M, Moulin M, Mitschler A, et al.
    High-resolution neutron and X-ray diffraction room-temperature studies of an H-FABP-oleic acid complex: Study of the internal water cluster and ligand binding by a transferred multipolar electron-density distribution
    IUCrJ. 2016; 3: 115-126. https://doi.org/10.1107/S2052252515024161
    DORA PSI
  • Huang C-Y, Olieric V, Ma P, Howe N, Vogeley L, Liu X, et al.
    In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures
    Acta Crystallographica Section D: Structural Biology. 2016; 72(1): 93-112. https://doi.org/10.1107/S2059798315021683
    DORA PSI
  • Jaeger K, Dworkowski F, Nogly P, Milne C, Wang M, Standfuss J
    Serial millisecond crystallography of membrane proteins
    In: Moraes I, ed. The next generation in membrane protein structure determination. Advances in experimental medicine and biology. Cham: Springer; 2016. https://doi.org/10.1007/978-3-319-35072-1_10
    DORA PSI
  • Lampart S, Roch LM, Dutta AK, Wang Y, Warshamanage R, Finke AD, et al.
    Pentaindenocorannulene: Properties, Assemblies, and C60Complex
    Angewandte Chemie International Edition. 2016; 55(47): 14648-14652. https://doi.org/10.1002/anie.201608337
    DORA PSI
  • Mallinger A, Schiemann K, Rink C, Sejberg J, Honey MA, Czodrowski P, et al.
    2,8-Disubstituted-1,6-Naphthyridines and 4,6-Disubstituted-Isoquinolines with Potent, Selective Affinity for CDK8/19
    ACS Medicinal Chemistry Letters. 2016; 7(6): 573-578. https://doi.org/10.1021/acsmedchemlett.6b00022
    DORA PSI
  • Marsh ME, Scott DE, Ehebauer MT, Abell C, Blundell TL, Hyvönen M
    ATP half-sites in RadA and RAD51 recombinases bind nucleotides
    FEBS Open Bio. 2016; 6(5): 372-385. https://doi.org/10.1002/2211-5463.12052
    DORA PSI
  • Moschetti T, Sharpe T, Fischer G, Marsh ME, Ng HK, Morgan M, et al.
    Engineering archeal surrogate systems for the development of protein-protein interaction inhibitors against human RAD51
    Journal of Molecular Biology. 2016; 428(23): 4589-4607. https://doi.org/10.1016/j.jmb.2016.10.009
    DORA PSI
  • Olieric V, Weinert T, Finke AD, Anders C, Li D, Olieric N, et al.
    Data-collection strategy for challenging native SAD phasing
    Acta Crystallographica Section D: Structural Biology. 2016; 72(3): 421-429. https://doi.org/10.1107/S2059798315024110
    DORA PSI
  • Orts J, Wälti MA, Marsh M, Vera L, Gossert AD, Güntert P, et al.
    NMR-based determination of the 3D structure of the ligand-protein interaction site without protein resonance assignment
    Journal of the American Chemical Society. 2016; 138(13): 4393-4400. https://doi.org/10.1021/jacs.5b12391
    DORA PSI
  • Schaffer MF, Peng G, Spingler B, Schnabl J, Wang M, Olieric V, et al.
    The x-ray structures of six octameric RNA duplexes in the presence of different di- and trivalent cations
    International Journal of Molecular Sciences. 2016; 17(7): 988. https://doi.org/10.3390/ijms17070988
    DORA PSI
  • Scott DE, Marsh M, Blundell TL, Abell C, Hyvönen M
    Structure-activity relationship of the peptide binding-motif mediating the BRCA2:RAD51 protein-protein interaction
    FEBS Letters. 2016; 590(8): 1094-1102. https://doi.org/10.1002/1873-3468.12139
    DORA PSI
  • Sumy DP, Finke AD, Whalley AC
    The reductive aromatization of tridecacyclene
    Chemical Communications. 2016; 52(83): 12368-12371. https://doi.org/10.1039/c6cc06078a
    DORA PSI
  • Sumy DP, Dodge NJ, Harrison CM, Finke AD, Whalley AC
    Tridecacyclene: A Cyclic Tetramer of Acenaphthylene
    Chemistry: A European Journal. 2016; 22(14): 4709-4712. https://doi.org/10.1002/chem.201600165
    DORA PSI
  • Tong S, Lin Y, Lu S, Wang M, Bogdanov M, Zheng L
    Structural insight into substrate selection and catalysis of lipid phosphate phosphatase PgpB in the cell membrane
    Journal of Biological Chemistry. 2016; 291(35): 18342-18352. https://doi.org/10.1074/jbc.M116.737874
    DORA PSI
  • Tsujino S, Tomizaki T
    Ultrasonic acoustic levitation for fast frame rate X-ray protein crystallography at room temperature
    Scientific Reports. 2016; 6: 25558. https://doi.org/10.1038/srep25558
    DORA PSI
  • Wojdyla JA, Panepucci E, Martiel I, Ebner S, Huang C-Y, Caffrey M, et al.
    Fast two-dimensional grid and transmission X-ray microscopy scanning methods for visualizing and characterizing protein crystals
    Journal of Applied Crystallography. 2016; 49: 944-952. https://doi.org/10.1107/S1600576716006233
    DORA PSI
  • Zhou XE, Gao X, Barty A, Kang Y, He Y, Liu W, et al.
    X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex
    Scientific Data. 2016; 3: 201621. https://doi.org/10.1038/sdata.2016.21
    DORA PSI
  • Bheemireddy SR, Ubaldo PC, Rose PW, Finke AD, Zhuang J, Wang L, et al.
    Stabilizing Pentacene by Cyclopentannulation
    Angewandte Chemie International Edition. 2015; 54(52): 15762-15766. https://doi.org/10.1002/anie.201508650
    DORA PSI
  • Botha S, Nass K, Barends T, Kabsch W, Latz B, Dworkowski F, et al.
    Room-temperature serial crystallography at synchrotron X-ray sources using slowly flowing free-standing high-viscosity microstreams
    Acta Crystallographica Section D: Structural Biology. 2015; 71: 387-397. https://doi.org/10.1107/S1399004714026327
    DORA PSI
  • Chang S, Sun D, Liang H, Wang J, Li J, Guo L, et al.
    Cryo-EM Structure of Influenza Virus RNA Polymerase Complex at 4.3Å Resolution
    Molecular Cell. 2015; 57(5): 925-935. https://doi.org/10.1016/j.molcel.2014.12.031
    DORA PSI
  • Chiu E, Hijnen M, Bunker R, Boudes M, Rajendran C, Olieric V, et al.
    Structural basis for the enhancement of virulence by viral spindles and their in vivo crystallization
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2015; 112(13): 3973-3978. https://doi.org/10.1073/pnas.1418798112
    DORA PSI
  • Demurtas D, Guichard P, Martiel I, Mezzenga R, Hébert C, Sagalowicz L
    Direct visualization of dispersed lipid bicontinuous cubic phases by cryo-electron tomography
    Nature Communications. 2015; 6: 8915. https://doi.org/10.1038/ncomms9915
    DORA PSI
  • Diaz A, Malkova B, Holler M, Guizar-Sicairos M, Lima E, Panneels V, et al.
    Three-dimensional mass density mapping of cellular ultrastructure by ptychographic X-ray nanotomography
    Journal of Structural Biology. 2015; 192(3): 461-469. https://doi.org/10.1016/j.jsb.2015.10.008
    DORA PSI
  • Dworkowski FSN, Hough MA, Pompidor G, Fuchs MR
    Challenges and solutions for the analysis of in situ, in crystallo micro-spectrophotometric data
    Acta Crystallographica Section D: Structural Biology. 2015; 71: 27-35. https://doi.org/10.1107/S1399004714015107
    DORA PSI
  • Ghafoor DD, Kekilli D, Abdullah GH, Dworkowski FSN, Hassan HG, Wilson MT, et al.
    Hydrogen bonding of the dissociated histidine ligand is not required for formation of a proximal NO adduct in cytochrome c'
    Journal of Biological Inorganic Chemistry. 2015; 20(6): 949-956. https://doi.org/10.1007/s00775-015-1278-y
    DORA PSI
  • Huang C-Y, Olieric V, Ma P, Panepucci E, Diederichs K, Wang M, et al.
    In meso in situ serial X-ray crystallography of soluble and membrane proteins
    Acta Crystallographica Section D: Structural Biology. 2015; 71(6): 1238-1256. https://doi.org/10.1107/S1399004715005210
    DORA PSI
  • Kang Y, Zhou XE, Gao X, He Y, Liu W, Ishchenko A, et al.
    Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
    Nature. 2015; 523(7562): 561-567. https://doi.org/10.1038/nature14656
    DORA PSI
  • Krüger H, Többens DM, Tropper P, Haefeker U, Kahlenberg V, Fuchs MR, et al.
    Single-crystal structure and Raman spectroscopy of synthetic titanite analog CaAlSiO4F
    Mineralogy and Petrology. 2015; 109(5): 631-641. https://doi.org/10.1007/s00710-015-0393-3
    DORA PSI
  • Martiel I, Baumann N, Vallooran JJ, Bergfreund J, Sagalowicz L, Mezzenga R
    Oil and drug control the release rate from lyotropic liquid crystals
    Journal of Controlled Release. 2015; 204: 78-84. https://doi.org/10.1016/j.jconrel.2015.02.034
    DORA PSI
  • Waltersperger S, Olieric V, Pradervand C, Glettig W, Salathe M, Fuchs MR, et al.
    PRIGo: a new multi-axis goniometer for macromolecular crystallography
    Journal of Synchrotron Radiation. 2015; 22: 895-900. https://doi.org/10.1107/S1600577515005354
    DORA PSI
  • Wang M, Zander T, Liu X, Liu C, Raj A, Florian Wieland DC, et al.
    The effect of temperature on supported dipalmitoylphosphatidylcholine (DPPC) bilayers: Structure and lubrication performance
    Journal of Colloid and Interface Science. 2015; 445: 84-92. https://doi.org/10.1016/j.jcis.2014.12.042
    DORA PSI
  • Weinert T, Olieric V, Waltersperger S, Panepucci E, Chen L, Zhang H, et al.
    Fast native-SAD phasing for routine macromolecular structure determination
    Nature Methods. 2015; 12(2): 131-133. https://doi.org/10.1038/nmeth.3211
    DORA PSI
  • Xia L, Lin H, Staniek A, Panjikar S, Ruppert M, Hilgers P, et al.
    Ligand structures of synthetic deoxa-pyranosylamines with raucaffricine and strictosidine glucosidases provide structural insights into their binding and inhibitory behaviours
    Journal of Enzyme Inhibition and Medicinal Chemistry. 2015; 30(3): 472-478. https://doi.org/10.3109/14756366.2014.949252
    DORA PSI
  • Zhu H, Kerčmar P, Wu F, Rajendran C, Sun L, Wang M, et al.
    Using strictosidine synthase to prepare novel alkaloids
    Current Medicinal Chemistry. 2015; 22(15): 1880-1888. https://doi.org/10.2174/0929867322666150408110919
    DORA PSI
  • Angelaccio S, Dworkowski F, Di Bello A, Milano T, Capitani G, Pascarella S
    Conformational transitions driven by pyridoxal-5′-phosphate uptake in the psychrophilic serine hydroxymethyltransferase from Psychromonas ingrahamii
    Proteins. 2014; 82(10): 2831-2841. https://doi.org/10.1002/prot.24646
    DORA PSI
  • Bartoloni M, Waltersperger S, Bumann M, Stocker A, Darbre T, Reymond J-L
    Stereoselective synthesis and structure determination of a bicyclo[3.3.2]decapeptide
    Arkivoc. 2014; 2014(3): 113-123. https://doi.org/10.3998/ark.5550190.p008.500
    DORA PSI
  • Benoit RM, Frey D, Hilbert M, Kevenaar JT, Wieser MM, Stirnimann CU, et al.
    Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A
    Nature. 2014; 505(7481): 108-111. https://doi.org/10.1038/nature12732
    DORA PSI
  • Bolze CS, Helbling RE, Owen RL, Pearson AR, Pompidor G, Dworkowski F, et al.
    Human cellular retinaldehyde-binding protein has secondary thermal 9-cis-retinal isomerase activity
    Journal of the American Chemical Society. 2014; 136(1): 137-146. https://doi.org/10.1021/ja411366w
    DORA PSI
  • Campagne S, Marsh ME, Capitani G, Vorholt JA, Allain FH-T
    Structural basis for -10 promoter element melting by environmentally induced sigma factors
    Nature Structural and Molecular Biology. 2014; 21(3): 269-276. https://doi.org/10.1038/nsmb.2777
    DORA PSI
  • Chong H, Yao X, Qiu Z, Sun J, Qiao Y, Zhang M, et al.
    The M-T hook structure increases the potency of HIV-1 fusion inhibitor sifuvirtide and overcomes drug resistance
    Journal of Antimicrobial Chemotherapy. 2014; 69(10): 2759-2769. https://doi.org/10.1093/jac/dku183
    DORA PSI
  • D'Arcy A, Bergfors T, Cowan-Jacob SW, Marsh M
    Microseed matrix screening for optimization in protein crystallization: What have we learned?
    Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 2014; 70: 1117-1126. https://doi.org/10.1107/S2053230X14015507
    DORA PSI
  • Fuchs MR, Pradervand C, Thominet V, Schneider R, Panepucci E, Grunder M, et al.
    D3, the new diffractometer for the macromolecular crystallography beamlines of the Swiss Light Source
    Journal of Synchrotron Radiation. 2014; 21(2): 340-351. https://doi.org/10.1107/S160057751400006X
    DORA PSI
  • Hassaine G, Deluz C, Grasso L, Wyss R, Tol MB, Hovius R, et al.
    X-ray structure of the mouse serotonin 5-HT3 receptor
    Nature. 2014; 512(7514): 276-281. https://doi.org/10.1038/nature13552
    DORA PSI
  • Kekilli D, Dworkowski FSN, Pompidor G, Fuchs MR, Andrew CR, Antonyuk S, et al.
    Fingerprinting redox and ligand states in haemprotein crystal structures using resonance Raman spectroscopy
    Acta Crystallographica Section D: Structural Biology. 2014; 70(5): 1289-1296. https://doi.org/10.1107/S1399004714004039
    DORA PSI
  • Krüger H, Tropper P, Haefeker U, Kaindl R, Tribus M, Kahlenberg V, et al.
    Innsbruckite, Mn33(Si2O5)14(OH)38 – a new mineral from the Tyrol, Austria
    Mineralogical Magazine. 2014; 78(7): 1613-1627. https://doi.org/10.1180/minmag.2014.078.7.06
    DORA PSI
  • Li D, Howe N, Dukkipati A, Shah STA, Bax BD, Edge C, et al.
    Crystallizing membrane proteins in the lipidic mesophase. Experience with human prostaglandin E2 synthase 1 and an evolving strategy
    Crystal Growth and Design. 2014; 14(4): 2034-2047. https://doi.org/10.1021/cg500157x
    DORA PSI
  • Meyer M, Nielsen H, Oliéric V, Roblin P, Johansen SD, Westhof E, et al.
    Speciation of a group i intron into a lariat capping ribozyme
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2014; 111(21): 7659-7664. https://doi.org/10.1073/pnas.1322248111
    DORA PSI
  • Prota AE, Bargsten K, Diaz JF, Marsh M, Cuevas C, Liniger M, et al.
    A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2014; 111(38): 13817-13821. https://doi.org/10.1073/pnas.1408124111
    DORA PSI
  • Prota AE, Bargsten K, Northcote PT, Marsh M, Altmann K-H, Miller JH, et al.
    Structural basis of microtubule stabilization by laulimalide and peloruside A
    Angewandte Chemie International Edition. 2014; 53(6): 1621-1625. https://doi.org/10.1002/anie.201307749
    DORA PSI
  • Weber S, Stirnimann CU, Wieser M, Frey D, Meier R, Engelhardt S, et al.
    A type IV translocated Legionella cysteine phytase counteracts intracellular growth restriction by phytate
    Journal of Biological Chemistry. 2014; 289(49): 34175-34188. https://doi.org/10.1074/jbc.M114.592568
    DORA PSI
  • Wolff P, Amal I, Oliéric V, Chaloin O, Gygli G, Ennifar E, et al.
    Differential modes of peptide binding onto replicative sliding clamps from various bacterial origins
    Journal of Medicinal Chemistry. 2014; 57(18): 7565-7576. https://doi.org/10.1021/jm500467a
    DORA PSI
  • Bjelić S, Wieser M, Frey D, Stirnimann CU, Chance MR, Jaussi R, et al.
    Structural Basis for the Oligomerization-State Switch from a Dimer to a Trimer of an Engineered Cortexillin-1 Coiled-Coil Variant
    PLoS One. 2013; 8(5): e63370. https://doi.org/10.1371/journal.pone.0063370
    DORA PSI
  • Bousset L, Pieri L, Ruiz-Arlandis G, Gath J, Jensen PH, Habenstein B, et al.
    Structural and functional characterization of two alpha-synuclein strains
    Nature Communications. 2013; 4: 2575 (13 pp.). https://doi.org/10.1038/ncomms3575
    DORA PSI
  • Chong H, Yao X, Qiu Z, Sun J, Zhang M, Waltersperger S, et al.
    Short-peptide fusion inhibitors with high potency against wild-type and enfuvirtide-resistant HIV-1
    FASEB Journal. 2013; 27(3): 1203-1213. https://doi.org/10.1096/fj.12-222547
    DORA PSI
  • Feng S, Chen Y, Kamada K, Wang H, Tang K, Wang M, et al.
    YoeB-ribosome structure: A canonical RNase that requires the ribosome for its specific activity
    Nucleic Acids Research. 2013; 41(20): 9549-9556. https://doi.org/10.1093/nar/gkt742
    DORA PSI
  • Gao X, Zou T, Mu Z, Qin B, Yang J, Waltersperger S, et al.
    Structural insights into VirB-DNA complexes reveal mechanism of transcriptional activation of virulence genes
    Nucleic Acids Research. 2013; 41(22): 10529-10541. https://doi.org/10.1093/nar/gkt748
    DORA PSI
  • Merlino A, Fuchs MR, Pica A, Balsamo A, Dworkowski FSN, Pompidor G, et al.
    Selective X-ray-induced NO photodissociation in haemoglobin crystals: Evidence from a Raman-assisted crystallographic study
    Acta Crystallographica Section D: Structural Biology. 2013; 69(1): 137-140. https://doi.org/10.1107/S0907444912042229
    DORA PSI
  • Pinker F, Brun M, Morin P, Deman A-L, Chateaux J-F, Oliéric V, et al.
    ChipX: A novel microfluidic chip for counter-diffusion crystallization of biomolecules and in situ crystal analysis at room temperature
    Crystal Growth and Design. 2013; 13(8): 3333-3340. https://doi.org/10.1021/cg301757g
    DORA PSI
  • Pompidor G, Dworkowski FSN, Thominet V, Schulze-Briese C, Fuchs MR
    A new on-axis micro-spectrophotometer for combining Raman, fluorescence and UV/Vis absorption spectroscopy with macromolecular crystallography at the Swiss Light Source
    Journal of Synchrotron Radiation. 2013; 20(5): 765-776. https://doi.org/10.1107/S0909049513016063
    DORA PSI
  • Ran T, Gao Y, Marsh M, Zhu W, Wang M, Mao X, et al.
    Crystal structures of Cg1458 reveal a catalytic lid domain and a common catalytic mechanism for the FAH family
    Biochemical Journal. 2013; 449(1): 51-60. https://doi.org/10.1042/BJ20120913
    DORA PSI
  • Richters A, Ketzer J, Getlik M, Grütter C, Schneider R, Heuckmann JM, et al.
    Targeting gain of function and resistance mutations in Abl and KIT by hybrid compound design
    Journal of Medicinal Chemistry. 2013; 56(14): 5757-5772. https://doi.org/10.1021/jm4004076
    DORA PSI
  • Schacherl M, Waltersperger S, Baumann U
    Structural characterization of the ribonuclease H-like type ASKHA superfamily kinase MK0840 from Methanopyrus kandleri
    Acta Crystallographica Section D: Structural Biology. 2013; 69(12): 2440-2450. https://doi.org/10.1107/S0907444913022683
    DORA PSI
  • Truan D, Vasil A, Stonehouse M, Vasil ML, Pohl E
    High-level over-expression, purification, and crystallization of a novel phospholipase C/sphingomyelinase from Pseudomonas aeruginosa
    Protein Expression and Purification. 2013; 90(1): 40-46. https://doi.org/10.1016/j.pep.2012.11.005
    DORA PSI
  • Wu M, Tong S, Waltersperger S, Diederichs K, Wang M, Zheng L
    Crystal structure of Ca2+/H+ antiporter protein YfkE reveals the mechanisms of Ca2+ efflux and its pH regulation
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2013; 110(28): 11367-11372. https://doi.org/10.1073/pnas.1302515110
    DORA PSI
  • Xia L, Rajendran C, Ruppert M, Panjikar S, Wang M, Stoeckigt J
    High speed X-ray analysis of plant enzymes at room temperature
    Phytochemistry. 2013; 91: 88-92. https://doi.org/10.1016/j.phytochem.2012.05.009
    DORA PSI
  • Chong H, Yao X, Qiu Z, Qin B, Han R, Waltersperger S, et al.
    Discovery of critical residues for viral entry and inhibition through structural insight of HIV-1 fusion inhibitor CP621-652
    Journal of Biological Chemistry. 2012; 287(24): 20281-20289. https://doi.org/10.1074/jbc.M112.354126
    DORA PSI
  • Chong H, Yao X, Sun J, Qiu Z, Zhang M, Waltersperger S, et al.
    The M-T hook structure is critical for design of HIV-1 fusion inhibitors
    Journal of Biological Chemistry. 2012; 287(41): 34558-34568. https://doi.org/10.1074/jbc.M112.390393
    DORA PSI
  • Cousido-Siah A, Ayoub D, Berberián G, Bollo M, Van Dorsselaer A, Debaene F, et al.
    Structural and functional studies of ReP1-NCXSQ, a protein regulating the squid nerve Na+/Ca2+ exchanger
    Acta Crystallographica Section D: Structural Biology. 2012; 68(9): 1098-1107. https://doi.org/10.1107/S090744491202094X
    DORA PSI
  • Graef C, Schacherl M, Waltersperger S, Baumann U
    Crystal structures of archaemetzincin reveal a moldable substrate-binding site
    PLoS One. 2012; 7(8): e43863. https://doi.org/10.1371/journal.pone.0043863
    DORA PSI
  • He C, Fuchs MR, Ogata H, Knipp M
    Guanidine-ferroheme coordination in the mutant protein nitrophorin 4(L130R)
    Angewandte Chemie International Edition. 2012; 51(18): 4470-4473. https://doi.org/10.1002/anie.201108691
    DORA PSI
  • Lerch P, Quaroni L, Wambach J, Schneider J, Armstrong DB, Rossetti D, et al.
    IR beamline at the Swiss Light Source
    In: Vol. 359. Journal of physics: conference series. Institute of Physics Publishing; 2012. https://doi.org/10.1088/1742-6596/359/1/012003
    DORA PSI
  • Mueller U, Darowski N, Fuchs MR, Förster R, Hellmig M, Paithankar KS, et al.
    Facilities for macromolecular crystallography at the Helmholtz-Zentrum Berlin
    Journal of Synchrotron Radiation. 2012; 19(3): 442-449. https://doi.org/10.1107/S0909049512006395
    DORA PSI
  • Mueller M, Wang M, Schulze-Briese C
    Optimal fine φ-slicing for single-photon-counting pixel detectors
    Acta Crystallographica Section D: Structural Biology. 2012; 68(1): 42-56. https://doi.org/10.1107/S0907444911049833
    DORA PSI
  • Pham SQ, Pompidor G, Liu J, Li X-D, Li Z
    Evolving P450pyr hydroxylase for highly enantioselective hydroxylation at non-activated carbon atom
    Chemical Communications. 2012; 48(38): 4618-4620. https://doi.org/10.1039/c2cc30779k
    DORA PSI
  • Pradervand C, Bednarzik M, Schmitt B, Mozzanica A, Schulze-Briese C
    A CVD diamond based X-ray beam profile sensor combined with the Gotthard charge integrating readout
    Presented at: 11th International conference on synchrotron radiation instrumentation (SRI2012); July 9-13, 2012; Lyon, France.
    DORA PSI
  • Sun L, Chen Y, Rajendran C, Mueller U, Panjikar S, Wang M, et al.
    Crystal structure of perakine reductase, founding member of a novel Aldo-Keto Reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding
    Journal of Biological Chemistry. 2012; 287(14): 11213-11221. https://doi.org/10.1074/jbc.M111.335521
    DORA PSI
  • Wang N, Wang M, Gao Y, Ran T, Lan Y, Wang J, et al.
    Crystallization and preliminary X-ray crystallographic analysis of a blue-light-absorbing proteorhodopsin
    Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 2012; 68(3): 281-283. https://doi.org/10.1107/S1744309111043612
    DORA PSI
  • Wu F, Zhu H, Sun L, Rajendran C, Wang M, Ren X, et al.
    Scaffold tailoring by a newly detected pictet-spenglerase activity of strictosidine synthase: From the common tryptoline skeleton to the rare piperazino-indole framework
    Journal of the American Chemical Society. 2012; 134(3): 1498-1500. https://doi.org/10.1021/ja211524d
    DORA PSI
  • Xia L, Ruppert M, Wang M, Panjikar S, Lin H, Rajendran C, et al.
    Structures of alkaloid biosynthetic glucosidases decode substrate specificity
    ACS Chemical Biology. 2012; 7(1): 226-234. https://doi.org/10.1021/cb200267w
    DORA PSI
  • Yao X, Chong H, Zhang C, Waltersperger S, Wang M, Cui S, et al.
    Broad antiviral activity and crystal structure of HIV-1 fusion inhibitor sifuvirtide
    Journal of Biological Chemistry. 2012; 287(9): 6788-6796. https://doi.org/10.1074/jbc.M111.317883
    DORA PSI
  • Yao X, Chong H, Zhang C, Qiu Z, Qin B, Han R, et al.
    Structural basis of potent and broad HIV-1 fusion inhibitor CP32M
    Journal of Biological Chemistry. 2012; 287(32): 26618-26629. https://doi.org/10.1074/jbc.M112.381079
    DORA PSI
  • Zarrine-Afsar A, Barends TRM, Müller C, Fuchs MR, Lomb L, Schlichting I, et al.
    Crystallography on a chip
    Acta Crystallographica Section D: Structural Biology. 2012; 68(3): 321-323. https://doi.org/10.1107/S0907444911055296
    DORA PSI
  • Zou T, Yao X, Qin B, Zhang M, Cai L, Shang W, et al.
    Crystal structure of Pseudomonas aeruginosa Tsi2 reveals a stably folded superhelical antitoxin
    Journal of Molecular Biology. 2012; 417(4): 351-361. https://doi.org/10.1016/j.jmb.2012.01.040
    DORA PSI
  • Bingel-Erlenmeyer R, Olieric V, Grimshaw JPA, Gabadinho J, Wang X, Ebner SG, et al.
    SLS crystallization platform at beamline X06DA-A fully automated pipeline enabling in situ X-ray diffraction screening
    Crystal Growth and Design. 2011; 11(4): 916-923. https://doi.org/10.1021/cg101375j
    DORA PSI
  • Blaise M, Fréchin M, Oliéric V, Charron C, Sauter C, Lorber B, et al.
    Crystal structure of the archaeal asparagine synthetase: Interrelation with aspartyl-tRNA and asparaginyl-tRNA synthetases
    Journal of Molecular Biology. 2011; 412(3): 437-452. https://doi.org/10.1016/j.jmb.2011.07.050
    DORA PSI
  • Carroll L, Friedli P, Lerch P, Schneider J, Treyer D, Hunziker S, et al.
    Ultra-broadband infrared pump-probe spectroscopy using synchrotron radiation and a tuneable pump
    Review of Scientific Instruments. 2011; 82(6): 63101. https://doi.org/10.1063/1.3592332
    DORA PSI
  • Cui S, Wang J, Fan T, Qin B, Guo L, Lei X, et al.
    Crystal structure of human enterovirus 71 3C protease
    Journal of Molecular Biology. 2011; 408(3): 449-461. https://doi.org/10.1016/j.jmb.2011.03.007
    DORA PSI
  • Kitagawa D, Vakonakis I, Olieric N, Hilbert M, Keller D, Olieric V, et al.
    Structural basis of the 9-fold symmetry of centrioles
    Cell. 2011; 144(3): 364-375. https://doi.org/10.1016/j.cell.2011.01.008
    DORA PSI
  • Ostendorp T, Diez J, Heizmann CW, Fritz G
    The crystal structures of human S100B in the zinc- and calcium-loaded state at three pH values reveal zinc ligand swapping
    Biochimica et Biophysica Acta: Molecular Cell Research. 2011; 1813(5): 1083-1091. https://doi.org/10.1016/j.bbamcr.2010.10.006
    DORA PSI
  • Pauluhn A, Pradervand C, Rossetti D, Salathe M, Schulze-Briese C
    Automatic loop centring with a high-precision goniometer head at the SLS macromolecular crystallography beamlines
    Journal of Synchrotron Radiation. 2011; 18(4): 595-600. https://doi.org/10.1107/S0909049511011848
    DORA PSI
  • Rajendran C, Gerhardt ECM, Bjelic S, Gasperina A, Scarduelli M, Pedrosa FO, et al.
    Crystal structure of the GlnZ-DraG complex reveals a different form of P II-target interaction
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2011; 108(47): 18972-18976. https://doi.org/10.1073/pnas.1108038108
    DORA PSI
  • Rajendran C, Dworkowski FSN, Wang M, Schulze-Briese C
    Radiation damage in room-temperature data acquisition with the PILATUS 6M pixel detector
    Journal of Synchrotron Radiation. 2011; 18(3): 318-328. https://doi.org/10.1107/S090904951100968X
    DORA PSI
  • Regis Faro A, Carpentier P, Jonasson G, Pompidor G, Arcizet D, Demachy I, et al.
    Low-temperature chromophore isomerization reveals the photoswitching mechanism of the fluorescent protein Padron
    Journal of the American Chemical Society. 2011; 133(41): 16362-16365. https://doi.org/10.1021/ja207001y
    DORA PSI
  • Schellenberger P, Demangeat G, Lemaire O, Ritzenthaler C, Bergdoll M, Oliéric V, et al.
    Strategies for the crystallization of viruses: Using phase diagrams and gels to produce 3D crystals of Grapevine fanleaf virus
    Journal of Structural Biology. 2011; 174(2): 344-351. https://doi.org/10.1016/j.jsb.2011.02.007
    DORA PSI
  • Wang J, Fan T, Yao X, Wu Z, Guo L, Lei X, et al.
    Crystal structures of enterovirus 71 3C protease complexed with rupintrivir reveal the roles of catalytically important residues
    Journal of Virology. 2011; 85(19): 10021-10030. https://doi.org/10.1128/JVI.05107-11
    DORA PSI
  • Wolff P, Oliéric V, Briand JP, Chaloin O, Dejaegere A, Dumas P, et al.
    Structure-based design of short peptide ligands binding onto the E. coli processivity ring
    Journal of Medicinal Chemistry. 2011; 54(13): 4627-4637. https://doi.org/10.1021/jm200311m
    DORA PSI
  • van der Vaart B, Manatschal C, Grigoriev I, Olieric V, Gouveia SM, Bjelić S, et al.
    SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase
    Journal of Cell Biology. 2011; 193(6): 1083-1099. https://doi.org/10.1083/jcb.201012179
    DORA PSI
  • Butschi A, Titz A, Wälti MA, Olieric V, Paschinger K, Nöbauer K, et al.
    Caenorhabditis elegans N-glycan Core β-galactoside confers sensitivity towards nematotoxic fungal galectin CGL2
    PLoS Pathogens. 2010; 6(1): e1000717. https://doi.org/10.1371/journal.ppat.1000717
    DORA PSI
  • Koch M, Diez J, Wagner A, Fritz G
    Crystallization and calcium/sulfur SAD phasing of the human EF-hand protein S100A2
    Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 2010; 66(9): 1032-1036. https://doi.org/10.1107/S1744309110030691
    DORA PSI
  • Koch M, Chitayat S, Dattilo BM, Schiefner A, Diez J, Chazin WJ, et al.
    Structural Basis for Ligand Recognition and Activation of RAGE
    Structure. 2010; 18(10): 1342-1352. https://doi.org/10.1016/j.str.2010.05.017
    DORA PSI
  • Lack NA, Yam KC, Lowe EE, Horsman GP, Owen RL, Sim E, et al.
    Characterization of a carbon-carbon hydrolase from Mycobacterium tuberculosis involved in cholesterol metabolism
    Journal of Biological Chemistry. 2010; 285(1): 434-443. https://doi.org/10.1074/jbc.M109.058081
    DORA PSI
  • Lanz VA, Pŕev̂ot ASH, Alfarra MR, Weimer S, Mohr C, Decarlo PF, et al.
    Characterization of aerosol chemical composition with aerosol mass spectrometry in Central Europe: An overview
    Atmospheric Chemistry and Physics. 2010; 10(21): 10453-10471. https://doi.org/10.5194/acp-10-10453-2010
    DORA PSI
  • Meents A, Gutmann S, Wagner A, Schulze-Briese C
    Origin and temperature dependence of radiation damage in biological samples at cryogenic temperatures
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2010; 107(3): 1094-1099. https://doi.org/10.1073/pnas.0905481107
    DORA PSI
  • Oberti S, Möller D, Neild A, Dual J, Beyeler F, Nelson BJ, et al.
    Strategies for single particle manipulation using acoustic and flow fields
    Ultrasonics. 2010; 50(2): 247-257. https://doi.org/10.1016/j.ultras.2009.09.004
    DORA PSI
  • Truan D, Huergo LF, Chubatsu LS, Merrick M, Li X-D, Winkler FK
    A new PII protein structure identifies the 2-oxoglutarate binding site
    Journal of Molecular Biology. 2010; 400(3): 531-539. https://doi.org/10.1016/j.jmb.2010.05.036
    DORA PSI
  • Waltersperger S, Widmer C, Wang M, Baumann U
    Crystal structure of archaemetzincin AmzA from methanopyrus kandleri at 1.5 Å resolution
    Proteins. 2010; 78(12): 2720-2723. https://doi.org/10.1002/prot.22777
    DORA PSI
  • Wang M
    Crystal Structures of Progressive Ca2+ Binding States of the Ca2+ Sensor CBD1 from the CALX Na+/Ca2+ Exchanger Reveal Incremental Conformational Transitions
    Journal of Biological Chemistry. 2010; 285. https://doi.org/10.1074/jbc.M109.059162
    DORA PSI
  • Yeh JI, Pohl E, Truan D, He W, Sheldrick GM, Du S, et al.
    The crystal structure of non-modified and bipyridine-modified PNA duplexes
    Chemistry: A European Journal. 2010; 16(39): 11867-11875. https://doi.org/10.1002/chem.201000392
    DORA PSI
  • Bullock AN, Russo S, Amos A, Pagano N, Bregman H, Debreczeni JÉ, et al.
    Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor
    PLoS One. 2009; 4(10): e7112 (7 pp.). https://doi.org/10.1371/journal.pone.0007112
    DORA PSI
  • Coulibaly F, Chiu E, Gutmann S, Rajendran C, Haebel PW, Ikeda K, et al.
    The atomic structure of baculovirus polyhedra reveals the independent emergence of infectious crystals in DNA and RNA viruses
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2009; 106(52): 22205-22210. https://doi.org/10.1073/pnas.0910686106
    DORA PSI
  • Langenhan T, Prömel S, Mestek L, Esmaeili B, Waller-Evans H, Hennig C, et al.
    Latrophilin signaling links anterior-posterior tissue polarity and oriented cell divisions in the C. elegans embryo
    Developmental Cell. 2009; 17(4): 494-504. https://doi.org/10.1016/j.devcel.2009.08.008
    DORA PSI
  • Meents A, Dittrich B, Gutmann S
    A new aspect of specific radiation damage: Hydrogen abstraction from organic molecules
    Journal of Synchrotron Radiation. 2009; 16(2): 183-190. https://doi.org/10.1107/S0909049509002192
    DORA PSI
  • Mueller M, Grauschopf U, Maier T, Glockshuber R, Ban N
    The structure of a cytolytic α-helical toxin pore reveals its assembly mechanism
    Nature. 2009; 459(7247): 726-730. https://doi.org/10.1038/nature08026
    DORA PSI
  • Oberholzer AE, Bumann M, Hege T, Russo S, Baumann U
    Metzincin's canonical methionine is responsible for the structural integrity of the zinc-binding site
    Biological Chemistry. 2009; 390(9): 875-881. https://doi.org/10.1515/BC.2009.100
    DORA PSI
  • Oberti S, Möller D, Gutmann S, Neild A, Dual J
    Novel sample preparation technique for protein crystal X-ray crystallographic analysis combining microfluidics and acoustic manipulation
    Journal of Applied Crystallography. 2009; 42(4): 636-641. https://doi.org/10.1107/S0021889809019177
    DORA PSI
  • Olieric V, Rieder U, Lang K, Serganov A, Schulze-Briese C, Micura R, et al.
    A fast selenium derivatization strategy for crystallization and phasing of RNA structures
    RNA. 2009; 15(4): 707-715. https://doi.org/10.1261/rna.1499309
    DORA PSI
  • Oliéric V, Wolff P, Takeuchi A, Bec G, Birck C, Vitorino M, et al.
    SECIS-binding protein 2, a key player in selenoprotein synthesis, is an intrinsically disordered protein
    Biochimie. 2009; 91(8): 1003-1009. https://doi.org/10.1016/j.biochi.2009.05.004
    DORA PSI
  • Owen RL, Pearson AR, Meents A, Boehler P, Thominet V, Schulze-Briese C
    A new on-axis multimode spectrometer for the macromolecular crystallography beamlines of the Swiss Light Source
    Journal of Synchrotron Radiation. 2009; 16(2): 173-182. https://doi.org/10.1107/S0909049508040120
    DORA PSI
  • Owen RL, Holton JM, Schulze-Briese C, Garman EF
    Determination of X-ray flux using silicon pin diodes
    Journal of Synchrotron Radiation. 2009; 16(2): 143-151. https://doi.org/10.1107/S0909049508040429
    DORA PSI
  • Owen RL, Holton JM, Schulze-Briese C, Garman EF
    Response to Krumreys Comments on Determination of X-ray flux using silicon pin diodes by R. L. Owen et al. (2009). J. Synchrotron Rad. 16, 143-153
    Journal of Synchrotron Radiation. 2009; 16(5): 691-692. https://doi.org/10.1107/S0909049509023644
    DORA PSI
  • Russo S, Schweitzer J-E, Polen T, Bott M, Pohl E
    Crystal structure of the caseinolytic protease gene regulator, a transcriptional activator in actinomycetes
    Journal of Biological Chemistry. 2009; 284(8): 5208-5216. https://doi.org/10.1074/jbc.M806591200
    DORA PSI
  • Wagner A, Diez J, Schulze-Briese C, Schluckebier G
    Crystal structure of Ultralente - A microcrystalline insulin suspension
    Proteins. 2009; 74(4): 1018-1027. https://doi.org/10.1002/prot.22213
    DORA PSI
  • Wu M, Wang M, Nix J, Hryshko LV, Zheng L
    Crystal Structure of CBD2 from the Drosophila Na+/Ca2+ Exchanger: Diversity of Ca2+ Regulation and Its Alternative Splicing Modification
    Journal of Molecular Biology. 2009; 387(1): 104-112. https://doi.org/10.1016/j.jmb.2009.01.045
    DORA PSI
  • Yang L, Hill M, Wang M, Panjikar S, Stöckigt J
    Structural basis and enzymatic mechanism of the biosynthesis of C9- from C10-monoterpenoid indole alkaloids
    Angewandte Chemie International Edition. 2009; 48(28): 5211-5213. https://doi.org/10.1002/anie.200900150
    DORA PSI
  • Blaise M, Olieric V, Sauter C, Lorber B, Roy B, Karmakar S, et al.
    Crystal Structure of Glutamyl-Queuosine tRNAAsp Synthetase Complexed with l-Glutamate: Structural Elements Mediating tRNA-Independent Activation of Glutamate and Glutamylation of tRNAAsp Anticodon
    Journal of Molecular Biology. 2008; 381(5): 1224-1237. https://doi.org/10.1016/j.jmb.2008.06.053
    DORA PSI
  • Felderer K, Groves M, Diez J, Pohl E, Witt S
    Crystallization and preliminary X-ray analysis of the Thermoplasma acidophilum 20S proteasome in complex with protein substrates
    Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 2008; 64(10): 899-902. https://doi.org/10.1107/S1744309108026791
    DORA PSI
  • Koch M, Diez J, Fritz G
    Crystal structure of Ca2+-free S100A2 at 1.6-Å resolution
    Journal of Molecular Biology. 2008; 378(4): 933-942. https://doi.org/10.1016/j.jmb.2008.03.019
    DORA PSI
  • Malo GD, Wang M, Wu D, Stelling AL, Tonge PJ, Wachter RM
    Crystal Structure and Raman Studies of dsFP483, a Cyan Fluorescent Protein from Discosoma striata
    Journal of Molecular Biology. 2008; 378(4): 869-884. https://doi.org/10.1016/j.jmb.2008.02.069
    DORA PSI
  • Malojčić G, Owen RL, Grimshaw JPA, Brozzo MS, Dreher-Teo H, Glockshuber R
    A structural and biochemical basis for PAPS-independent sulfuryl transfer by aryl sulfotransferase from uropathogenic Escherichia coli
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2008; 105(49): 19217-19222. https://doi.org/10.1073/pnas.0806997105
    DORA PSI
  • Malojčić G, Owen RL, Grimshaw JPA, Glockshuber R
    Preparation and structure of the charge-transfer intermediate of the transmembrane redox catalyst DsbB
    FEBS Letters. 2008; 582(23-24): 3301-3307. https://doi.org/10.1016/j.febslet.2008.07.063
    DORA PSI
  • Pauluhn A, Ahmed H, Lorentzen E, Buchinger S, Schomburg D, Siebers B, et al.
    Crystal structure and stereochemical studies of KD(P)G aldolase from Thermoproteus tenax
    Proteins. 2008; 72(1): 35-43. https://doi.org/10.1002/prot.21890
    DORA PSI
  • Steinmetz MO, Gattin Z, Verel R, Ciani B, Stromer T, Green JM, et al.
    Atomic Models of De Novo Designed ccβ-Met Amyloid-Like Fibrils
    Journal of Molecular Biology. 2008; 376(3): 898-912. https://doi.org/10.1016/j.jmb.2007.11.100
    DORA PSI
  • Varco-Merth B, Fromme R, Wang M, Fromme P
    Crystallization of the c14-rotor of the chloroplast ATP synthase reveals that it contains pigments
    Biochimica et Biophysica Acta: Bioenergetics. 2008; 1777(7-8): 605-612. https://doi.org/10.1016/j.bbabio.2008.05.009
    DORA PSI

Associated Beamlines

Contact

Head of MX
and Group Leader (i.p.) MX Applications
Dr. Meitian Wang
Telephone:
+41 56 310 4175
E-mail:
meitian.wang@psi.ch

Group Leader MX Instrumentation
Wayne Glettig
Telephone:
+41 56 310 5823
E-mail:
wayne.glettig@psi.ch

Group Leader MX Samples
Dr. May Marsh
Telephone:
+41 56 310 5437
E-mail:
may.marsh@psi.ch