Publications

Recent publications are listed below. For an extensive overview we kindly refer you to our publication repository DORA

  • Alsarraf HMAB, Ung KL, Johansen MD, Dimon J, Olieric V, Kremer L, et al.
    Biochemical, structural, and functional studies reveal that MAB_4324c from Mycobacterium abscessus is an active tandem repeat N‐acetyltransferase
    FEBS Letters. 2022; 596(12): 1516-1532. https://doi.org/10.1002/1873-3468.14360
    DORA PSI
  • Bleuler-Martinez S, Varrot A, Olieric V, Schubert M, Vogt E, Fetz C, et al.
    Structure–function relationship of a novel fucoside-binding fruiting body lectin from Coprinopsis cinerea exhibiting nematotoxic activity
    Glycobiology. 2022; 32(7): 600-615. https://doi.org/10.1093/glycob/cwac020
    DORA PSI
  • Cellini A, Shankar MK, Wahlgren WY, Nimmrich A, Furrer A, James D, et al.
    Structural basis of the radical pair state in photolyases and cryptochromes
    Chemical Communications. 2022; 58(31): 4889-4892. https://doi.org/10.1039/D2CC00376G
    DORA PSI
  • Collu G, Bierig T, Krebs A-S, Engilberge S, Varma N, Guixà-González R, et al.
    Chimeric single α-helical domains as rigid fusion protein connections for protein nanotechnology and structural biology
    Structure. 2022; 30(1): 95-106. https://doi.org/10.1016/j.str.2021.09.002
    DORA PSI
  • Kaminski JW, Vera L, Stegmann DP, Vering J, Eris D, Smith KML, et al.
    Fast fragment- and compound-screening pipeline at the Swiss Light Source
    Acta Crystallographica Section D: Structural Biology. 2022; 78: 328-336. https://doi.org/10.1107/S2059798322000705
    DORA PSI
  • Kepa MW, Tomizaki T, Sato Y, Ozerov D, Sekiguchi H, Yasuda N, et al.
    Acoustic levitation and rotation of thin films and their application for room temperature protein crystallography
    Scientific Reports. 2022; 12: 5349 (14 pp.). https://doi.org/10.1038/s41598-022-09167-z
    DORA PSI
  • Mertens V, Abi Saad MJ, Coudevylle N, Wälti MA, Finke A, Marsh M, et al.
    Elucidation of a nutlin-derivative-HDM2 complex structure at the interaction site by NMR molecular replacement: a straightforward derivation
    Journal of Magnetic Resonance Open. 2022; 10-11: 100032 (5 pp.). https://doi.org/10.1016/j.jmro.2022.100032
    DORA PSI
  • Mous S, Gotthard G, Ehrenberg D, Sen S, Weinert T, Johnson PJM, et al.
    Dynamics and mechanism of a light-driven chloride pump
    Science. 2022; 375(6583): 845-851. https://doi.org/10.1126/science.abj6663
    DORA PSI
  • Pedrini B, Finke AD, Marsh M, Luporini P, Vallesi A, Alimenti C
    Crystal structure of the pheromone Er-13 from the ciliate Euplotes raikovi, with implications for a protein-protein association model in pheromone/receptor interactions
    Journal of Structural Biology. 2022; 214(1): 107812 (10 pp.). https://doi.org/10.1016/j.jsb.2021.107812
    DORA PSI
  • Xu Q, Sun N, Xiao Q, Huang C-ying, Xu M, Zhang W, et al.
    The crystal structure of MreC provides insights into polymer formation
    FEBS Open Bio. 2022; 12(2): 340-348. https://doi.org/10.1002/2211-5463.13296
    DORA PSI
  • Ashton A, Augustin S, Babic A, Celcer T, Ebner SG, Egli S, et al.
    Conceptual design report on controls and science IT for the SLS 2.0 upgrade project
    Villigen PSI, Switzerland: Paul Scherrer Institut; 2021. PSI Bericht: 21-03.
    DORA PSI
  • Beale JH, Marsh ME
    Optimizing the growth of endothiapepsin crystals for serial crystallography experiments
    Journal of Visualized Experiments. 2021; 168: e61896 (30 pp.). https://doi.org/10.3791/61896
    DORA PSI
  • Braun H, Garvey T, Jörg M, Ashton A, Willmott P, Kobler R, et al.
    SLS 2.0 storage ring. Technical design report
    Villigen PSI, Switzerland: Paul Scherrer Institut; 2021. PSI Bericht: 21-02.
    DORA PSI
  • Butryn A, Simon PS, Aller P, Hinchliffe P, Massad RN, Leen G, et al.
    An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography
    Nature Communications. 2021; 12(1): 4461 (7 pp.). https://doi.org/10.1038/s41467-021-24757-7
    DORA PSI
  • Cinquino M, Fieramosca A, Mastria R, Polimeno L, Moliterni A, Olieric V, et al.
    Managing growth and dimensionality of quasi 2D perovskite single-crystalline flakes for tunable excitons orientation
    Advanced Materials. 2021; 33(48): 2102326 (9 pp.). https://doi.org/10.1002/adma.202102326
    DORA PSI
  • Dhanabalan B, Biffi G, Moliterni A, Olieric V, Giannini C, Saleh G, et al.
    Engineering the optical emission and robustness of metal-halide layered perovskites through ligand accommodation
    Advanced Materials. 2021; 33(13): 2008004 (11 pp.). https://doi.org/10.1002/adma.202008004
    DORA PSI
  • Gao X, Zhu K, Qin B, Olieric V, Wang M, Cui S
    Crystal structure of SARS-CoV-2 Orf9b in complex with human TOM70 suggests unusual virus-host interactions
    Nature Communications. 2021; 12(1): 2843 (9 pp.). https://doi.org/10.1038/s41467-021-23118-8
    DORA PSI
  • Gao X, Qin B, Chen P, Zhu K, Hou P, Wojdyla JA, et al.
    Crystal structure of SARS-CoV-2 papain-like protease
    Acta Pharmaceutica Sinica B. 2021; 11(1): 237-245. https://doi.org/10.1016/j.apsb.2020.08.014
    DORA PSI
  • Gao C, Stavenhagen K, Eckmair B, McKitrick TR, Mehta AY, Matsumoto Y, et al.
    Differential recognition of oligomannose isomers by glycan-binding proteins involved in innate and adaptive immunity
    Science Advances. 2021; 7(24): eabf6834 (12 pp.). https://doi.org/10.1126/sciadv.abf6834
    DORA PSI
  • Hahn CJ, Lemaire ON, Kahnt J, Engilberge S, Wegener G, Wagner T
    Crystal structure of a key enzyme for anaerobic ethane activation
    Science. 2021; 373(6550): 118-121. https://doi.org/10.1126/science.abg1765
    DORA PSI
  • Iorio A, Roche J, Engilberge S, Coquelle N, Girard E, Sterpone F, et al.
    Biochemical, structural and dynamical studies reveal strong differences in the thermal-dependent allosteric behavior of two extremophilic lactate dehydrogenases
    Journal of Structural Biology. 2021; 213(3): 107769 (11 pp.). https://doi.org/10.1016/j.jsb.2021.107769
    DORA PSI
  • Kepa MW, Tomizaki T, Tsujino S
    Development of on-demand sample loading of ultrasound acoustic levitators by focused acoustic radiation
    In: IEEE international ultrasonics symposium (IUS 2021). Danvers, MA: IEEE; 2021. https://doi.org/10.1109/IUS52206.2021.9593735
    DORA PSI
  • Li H, Huang C-Y, Govorunova EG, Sineshchekov OA, Yi A, Rothschild KJ, et al.
    The crystal structure of bromide-bound GtACR1 reveals a pre-activated state in the transmembrane anion tunnel
    eLife. 2021; 10: e65903 (14 pp.). https://doi.org/10.7554/eLife.65903
    DORA PSI
  • Martiel I, Beale JH, Karpik A, Huang C-Y, Vera L, Olieric N, et al.
    Versatile microporous polymer-based supports for serial macromolecular crystallography
    Acta Crystallographica Section D: Structural Biology. 2021; 77(9): 1153-1167. https://doi.org/10.1107/S2059798321007324
    DORA PSI
  • Monsarrat C, Compain G, André C, Engilberge S, Martiel I, Oliéric V, et al.
    Iterative structure-based optimization of short peptides targeting the bacterial sliding clamp
    Journal of Medicinal Chemistry. 2021; 64(23): 17063-17078. https://doi.org/10.1021/acs.jmedchem.1c00918
    DORA PSI
  • Mühlethaler T, Gioia D, Prota AE, Sharpe ME, Cavalli A, Steinmetz MO
    Comprehensive analysis of binding sites in tubulin
    Angewandte Chemie International Edition. 2021; 60(24): 13331-13342. https://doi.org/10.1002/anie.202100273
    DORA PSI
  • Nasrallah C, Cannone G, Briot J, Rottier K, Berizzi AE, Huang CY, et al.
    Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations
    Cell Reports. 2021; 36(9): 109648. https://doi.org/10.1016/j.celrep.2021.109648
    DORA PSI
  • Nass K, Bacellar C, Cirelli C, Dworkowski F, Gevorkov Y, James D, et al.
    Pink-beam serial femtosecond crystallography for accurate structure-factor determination at an X-ray free-electron laser
    IUCrJ. 2021; 8: 905-920. https://doi.org/10.1107/S2052252521008046
    DORA PSI
  • Ni X, Schröder M, Olieric V, Sharpe ME, Hernandez-Olmos V, Proschak E, et al.
    Structural insights into plasticity and discovery of remdesivir metabolite GS-441524 binding in SARS-CoV-2 macrodomain
    ACS Medicinal Chemistry Letters. 2021; 12(4): 603-609. https://doi.org/10.1021/acsmedchemlett.0c00684
    DORA PSI
  • Olatunji S, Bowen K, Huang CY, Weichert D, Singh W, Tikhonova IG, et al.
    Structural basis of the membrane intramolecular transacylase reaction responsible for lyso-form lipoprotein synthesis
    Nature Communications. 2021; 12(1): 4254 (14 pp.). https://doi.org/10.1038/s41467-021-24475-0
    DORA PSI
  • Palmerini V, Monzani S, Laurichesse Q, Loudhaief R, Mari S, Cecatiello V, et al.
    Drosophila TNFRs Grindelwald and Wengen bind Eiger with different affinities and promote distinct cellular functions
    Nature Communications. 2021; 12(1): 2070 (12 pp.). https://doi.org/10.1038/s41467-021-22080-9
    DORA PSI
  • Polimeno L, Lerario G, De Giorgi M, De Marco L, Dominici L, Todisco F, et al.
    Tuning of the Berry curvature in 2D perovskite polaritons
    Nature Nanotechnology. 2021; 16: 1349-1354. https://doi.org/10.1038/s41565-021-00977-2
    DORA PSI
  • Ramberg KO, Engilberge S, Skorek T, Crowley PB
    Facile fabrication of protein-macrocycle frameworks
    Journal of the American Chemical Society. 2021; 143(4): 1896-1907. https://doi.org/10.1021/jacs.0c10697
    DORA PSI
  • Ramos J, Laux V, Haertlein M, Boeri Erba E, McAuley KE, Forsyth VT, et al.
    Structural insights into protein folding, stability and activity using in vivo perdeuteration of hen egg-white lysozyme
    IUCrJ. 2021; 8: 372-386. https://doi.org/10.1107/S2052252521001299
    DORA PSI
  • Scott DE, Francis-Newton NJ, Marsh ME, Coyne AG, Fischer G, Moschetti T, et al.
    A small-molecule inhibitor of the BRCA2-RAD51 interaction modulates RAD51 assembly and potentiates DNA damage-induced cell death
    Cell Chemical Biology. 2021; 28(6): 835-847.e5. https://doi.org/10.1016/j.chembiol.2021.02.006
    DORA PSI
  • Sharpe ME, Wojdyla JA
    Fragment-screening and automation at the Swiss Light Source macromolecular crystallography beamlines
    Nihon Kessho Gakkaishi. 2021; 63(3): 232-235. https://doi.org/10.5940/jcrsj.63.232
    DORA PSI
  • Sutanto F, Shaabani S, Oerlemans R, Eris D, Patil P, Hadian M, et al.
    Combining high-throughput synthesis and high-throughput protein crystallography for accelerated hit identification
    Angewandte Chemie International Edition. 2021; 60(33): 18231-18239. https://doi.org/10.1002/anie.202105584
    DORA PSI
  • Toomey B, Han X, Dong CD, Edward V, Kaminski JW, Shankar S
    Characterization of phases and orientations of micro-structured materials Using computational crystallography
    In: Shankar S, Muller R, Dunning T, Chen GH, eds. Computational materials, chemistry, and biochemistry: from bold initiatives to the last mile. In honor of William A. Goddard’s contributions to science and engineering. Springer series in materials science. Cham: Springer; 2021:213-231. https://doi.org/10.1007/978-3-030-18778-1_11
    DORA PSI
  • de Wijn R, Rollet K, Olieric V, Hennig O, Thome N, Noûs C, et al.
    Crystallization and structural determination of an enzyme: substrate complex by serial crystallography in a versatile microfluidic chip
    Journal of Visualized Experiments. 2021; 2021(169): e61972 (15 pp.). https://doi.org/10.3791/61972
    DORA PSI
  • Assmann GM, Wang M, Diederichs K
    Making a difference in multi-data-set crystallography: simple and deterministic data-scaling/selection methods
    Acta Crystallographica Section D: Structural Biology. 2020; 76: 636-652. https://doi.org/10.1107/S2059798320006348
    DORA PSI
  • Beale JH
    Macromolecular X-ray crystallography: soon to be a road less travelled?
    Acta Crystallographica Section D: Structural Biology. 2020; 76(5): 400-405. https://doi.org/10.1107/S2059798320004660
    DORA PSI
  • Bedi RK, Huang D, Wiedmer L, Li Y, Dolbois A, Wojdyla JA, et al.
    Selectively disrupting m6A-dependent protein-RNA interactions with fragments
    ACS Chemical Biology. 2020; 15(3): 618-625. https://doi.org/10.1021/acschembio.9b00894
    DORA PSI
  • Bernstein HJ, Förster A, Bhowmick A, Brewster AS, Brockhauser S, Gelisio L, et al.
    Gold standard for macromolecular crystallography diffraction data
    IUCrJ. 2020; 7(5): 784-792. https://doi.org/10.1107/S2052252520008672
    DORA PSI
  • Bu W, Levitskaya Z, Loh ZY, Jin S, Basu S, Ero R, et al.
    Structural basis of human full-length kindlin-3 homotrimer in an auto-inhibited state
    PLoS Biology. 2020; 18(7): e3000755 (24 pp.). https://doi.org/10.1371/journal.pbio.3000755
    DORA PSI
  • Cheng R, Huang C-Y, Hennig M, Nar H, Schnapp G
    In situ crystallography as an emerging method for structure solution of membrane proteins: the case of CCR2A
    FEBS Journal. 2020; 287(5): 866-873. https://doi.org/10.1111/febs.15098
    DORA PSI
  • Cinquino M, Polimeno L, Lerario G, De Giorgi M, Moliterni A, Olieric V, et al.
    One-step synthesis at room temperature of low dimensional perovskite single crystals with high optical quality
    Journal of Luminescence. 2020; 221: 117079 (8 pp.). https://doi.org/10.1016/j.jlumin.2020.117079
    DORA PSI
  • Crack JC, Amara P, Volbeda A, Mouesca J-M, Rohac R, Pellicer Martinez MT, et al.
    Electron and proton transfers modulate DNA binding by the transcription regulator RsrR
    Journal of the American Chemical Society. 2020; 142(11): 5104-5116. https://doi.org/10.1021/jacs.9b12250
    DORA PSI
  • Engilberge S, Wagner T, Carpentier P, Girard E, Shima S
    Krypton-derivatization highlights O2-channeling in a four-electron reducing oxidase
    Chemical Communications. 2020; 56(74): 10863-10866. https://doi.org/10.1039/d0cc04557h
    DORA PSI
  • Fadini A, Reiche S, Nass K, van Thor JJ
    Applications and limits of time-to-energy mapping of protein crystal diffraction using energy-chirped polychromatic XFEL pulses
    Applied Sciences. 2020; 10(7): 2599 (18 pp.). https://doi.org/10.3390/app10072599
    DORA PSI
  • Gao X, Zhu K, Wojdyl JA, Chen P, Qin B, Li Z, et al.
    Crystal structure of the NS3-like helicase from Alongshan virus
    IUCrJ. 2020; 7(3): 375-382. https://doi.org/10.1107/S2052252520003632
    DORA PSI
  • Görlich S, Samuel AJ, Best RJ, Seidel R, Vacelet J, Leonarski FK, et al.
    Natural hybrid silica/protein superstructure at atomic resolution
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2020; 117(49): 31088-31093. https://doi.org/10.1073/pnas.2019140117
    DORA PSI
  • Huang C-Y, Meier N, Caffrey M, Wang M, Olieric V
    3D-printed holders for in meso in situ fixed-target serial X-ray crystallography
    Journal of Applied Crystallography. 2020; 53: 854-859. https://doi.org/10.1107/S1600576720002897
    DORA PSI
  • Huang C-Y, Olieric V, Caffrey M, Wang M
    In meso in situ serial X-Ray crystallography (IMISX): a protocol for membrane protein structure determination at the Swiss Light Source
    In: Perez C, Maier T, eds. Expression, purification, and structural biology of membrane proteins. Methods in molecular biology. New York: Humana; 2020:293-319. https://doi.org/10.1007/978-1-0716-0373-4_20
    DORA PSI
  • Huwald D, Duda S, Gasper R, Olieric V, Hofmann E, Hemschemeier A
    Distinctive structural properties of THB11, a pentacoordinate Chlamydomonas reinhardtii truncated hemoglobin with N- and C-terminal extensions
    Journal of Biological Inorganic Chemistry. 2020; 25: 267-283. https://doi.org/10.1007/s00775-020-01759-2
    DORA PSI
  • Karpik A, Martiel I, Kristiansen PM, Padeste C
    Fabrication of ultrathin suspended polymer membranes as supports for serial protein crystallography
    Micro and Nano Engineering. 2020; 7: 100053 (6 pp.). https://doi.org/10.1016/j.mne.2020.100053
    DORA PSI
  • Leonarski F, Mozzanica A, Brückner M, Lopez-Cuenca C, Redford S, Sala L, et al.
    JUNGFRAU detector for brighter x-ray sources: solutions for IT and data science challenges in macromolecular crystallography
    Structural Dynamics. 2020; 7(1): 014305 (13 pp.). https://doi.org/10.1063/1.5143480
    DORA PSI
  • Lučić M, Chaplin AK, Moreno-Chicano T, Dworkowski FSN, Wilson MT, Svistunenko DA, et al.
    A subtle structural change in the distal haem pocket has a remarkable effect on tuning hydrogen peroxide reactivity in dye decolourising peroxidases from Streptomyces lividans
    Dalton Transactions. 2020; 49(5): 1620-1636. https://doi.org/10.1039/c9dt04583j
    DORA PSI
  • Lučić M, Svistunenko DA, Wilson MT, Chaplin AK, Davy B, Ebrahim A, et al.
    Serial femtosecond zero dose crystallography captures a water-free distal heme site in a dye‐decolourising peroxidase to reveal a catalytic role for an arginine in FeIV=O formation
    Angewandte Chemie International Edition. 2020; 59(48): 21656-21662. https://doi.org/10.1002/anie.202008622
    DORA PSI
  • Martiel I, Huang C-Y, Villanueva-Perez P, Panepucci E, Basu S, Caffrey M, et al.
    Low-dose in situ prelocation of protein microcrystals by 2D X-ray phase-contrast imaging for serial crystallography
    IUCrJ. 2020; 7(6): 1131-1141. https://doi.org/10.1107/S2052252520013238
    DORA PSI
  • Martiel I, Buntschu D, Meier N, Gobbo A, Panepucci E, Schneider R, et al.
    The TELL automatic sample changer for macromolecular crystallography
    Journal of Synchrotron Radiation. 2020; 27: 860-863. https://doi.org/10.1107/S1600577520002416
    DORA PSI
  • Martiel I, Mozzanica A, Opara NL, Panepucci E, Leonarski F, Redford S, et al.
    X-ray fluorescence detection for serial macromolecular crystallography using a JUNGFRAU pixel detector
    Journal of Synchrotron Radiation. 2020; 27: 329-339. https://doi.org/10.1107/S1600577519016758
    DORA PSI
  • Moliterni A, Altamura D, Lassandro R, Olieric V, Ferri G, Cardarelli F, et al.
    Synthesis, crystal structure, polymorphism and microscopic luminescence properties of anthracene derivative compounds
    Acta Crystallographica Section B: Structural Science, Crystal Engineering and Materials. 2020; B76: 427-435. https://doi.org/10.1107/S2052520620004424
    DORA PSI
  • Nass K, Cheng R, Vera L, Mozzanica A, Redford S, Ozerov D, et al.
    Advances in long-wavelength native phasing at X-ray free-electron lasers
    IUCrJ. 2020; 7: 965-975. https://doi.org/10.1107/S2052252520011379
    DORA PSI
  • Nass K, Redecke L, Perbandt M, Yefanov O, Klinge M, Koopmann R, et al.
    In cellulo crystallization of Trypanosoma brucei IMP dehydrogenase enables the identification of genuine co-factors
    Nature Communications. 2020; 11(1): 620 (13 pp.). https://doi.org/10.1038/s41467-020-14484-w
    DORA PSI
  • Nass K
    Pixel modelling - a new age in SFX data analysis
    IUCrJ. 2020; 7: 949-950. https://doi.org/10.1107/S2052252520014281
    DORA PSI
  • Olatunji S, Yu X, Bailey J, Huang C-Y, Zapotoczna M, Bowen K, et al.
    Structures of lipoprotein signal peptidase II from Staphylococcus aureus complexed with antibiotics globomycin and myxovirescin
    Nature Communications. 2020; 11(1): 140 (11 pp.). https://doi.org/10.1038/s41467-019-13724-y
    DORA PSI
  • Pfanzagl V, Beale JH, Michlits H, Schmidt D, Gabler T, Obinger C, et al.
    X-ray-induced photoreduction of heme metal centers rapidly induces active-site perturbations in a protein-independent manner
    Journal of Biological Chemistry. 2020; 295(39): 13488-13501. https://doi.org/10.1074/jbc.ra120.014087
    DORA PSI
  • Prat E, Abela R, Aiba M, Alarcon A, Alex J, Arbelo Y, et al.
    A compact and cost-effective hard X-ray free-electron laser driven by a high-brightness and low-energy electron beam
    Nature Photonics. 2020; 14: 748-754. https://doi.org/10.1038/s41566-020-00712-8
    DORA PSI
  • Skopintsev P, Ehrenberg D, Weinert T, James D, Kar RK, Johnson PJM, et al.
    Femtosecond-to-millisecond structural changes in a light-driven sodium pump
    Nature. 2020; 583: 314-318. https://doi.org/10.1038/s41586-020-2307-8
    DORA PSI
  • Soman A, Liew CW, Teo HL, Berezhnoy NV, Olieric V, Korolev N, et al.
    The human telomeric nucleosome displays distinct structural and dynamic properties
    Nucleic Acids Research. 2020; 48(10): 5383-5396. https://doi.org/10.1093/nar/gkaa289
    DORA PSI
  • Steib E, Laporte MH, Gambarotto D, Olieric N, Zheng C, Borgers S, et al.
    WDR90 is a centriolar microtubule wall protein important for centriole architecture integrity
    eLife. 2020; 9: e57205 (28 pp.). https://doi.org/10.7554/ELIFE.57205
    DORA PSI
  • Tsujino S, Tomizaki T
    Applications of acoustic levitation in chemical analysis and biochemistry
    In: Zang D, ed. Acoustic levitation. From physics to applications. Singapore: Springer; 2020:151-179. https://doi.org/10.1007/978-981-32-9065-5_9
    DORA PSI
  • Tsujino S, Tomizaki T, Kepa MW
    On-demand droplet loading of ultrasonic acoustic levitator with small droplets for protein crystallography application
    In: Proceedings of the 2020 IEEE international ultrasonics symposium (IUS). IEEE symposium (IUS) ultrasonics. sine loco: IEEE; 2020:9251627 (3 pp.). https://doi.org/10.1109/IUS46767.2020.9251627
    DORA PSI
  • Ye F, Wang C, Fu Q, Yan X-F, Bharath SR, Casanas A, et al.
    Structural basis of a novel repressor, SghR, controlling Agrobacterium infection by cross-talking to plants
    Journal of Biological Chemistry. 2020; 295(34): 12290-12304. https://doi.org/10.1074/jbc.RA120.012908
    DORA PSI
  • Yu X, Gao X, Zhu K, Yin H, Mao X, Wojdyla JA, et al.
    Characterization of a toxin-antitoxin system in Mycobacterium tuberculosis suggests neutralization by phosphorylation as the antitoxicity mechanism
    Communications Biology. 2020; 3(1): 216 (15 pp.). https://doi.org/10.1038/s42003-020-0941-1
    DORA PSI
  • André C, Martiel I, Wolff P, Landolfo M, Lorber B, Silva da Veiga C, et al.
    Interaction of a model peptide on gram negative and gram positive bacterial sliding clamps
    ACS Infectious Diseases. 2019; 5: 1022-1034. https://doi.org/10.1021/acsinfecdis.9b00089
    DORA PSI
  • Apel A-K, Cheng RKY, Tautermann CS, Brauchle M, Huang C-Y, Pautsch A, et al.
    Crystal structure of CC chemokine receptor 2A in complex with an orthosteric antagonist provides insights for the design of selective antagonists
    Structure. 2019; 27(3): 427-438.e5. https://doi.org/10.1016/j.str.2018.10.027
    DORA PSI
  • Basu S, Kaminski JW, Panepucci E, Huang C-Y, Warshamanage R, Wang M, et al.
    Automated data collection and real-time data analysis suite for serial synchrotron crystallography
    Journal of Synchrotron Radiation. 2019; 26(1): 244-252. https://doi.org/10.1107/S1600577518016570
    DORA PSI
  • Basu S, Olieric V, Leonarski F, Matsugaki N, Kawano Y, Takashi T, et al.
    Long-wavelength native-SAD phasing: opportunities and challenges
    IUCrJ. 2019; 6(3): 1-14. https://doi.org/10.1107/S2052252519002756
    DORA PSI
  • Basu S, Finke A, Vera L, Wang M, Olieric V
    Making routine native SAD a reality: lessons from beamline X06DA at the Swiss Light Source
    Acta Crystallographica Section D: Structural Biology. 2019; 75(3): 262-271. https://doi.org/10.1107/S2059798319003103
    DORA PSI
  • Casadei CM, Nass K, Barty A, Hunter MS, Padeste C, Tsai C-J, et al.
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    Tridecacyclene: a cyclic tetramer of acenaphthylene
    Chemistry: A European Journal. 2016; 22(14): 4709-4712. https://doi.org/10.1002/chem.201600165
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  • Tong S, Lin Y, Lu S, Wang M, Bogdanov M, Zheng L
    Structural insight into substrate selection and catalysis of lipid phosphate phosphatase PgpB in the cell membrane
    Journal of Biological Chemistry. 2016; 291(35): 18342-18352. https://doi.org/10.1074/jbc.M116.737874
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    Ultrasonic acoustic levitation for fast frame rate X-ray protein crystallography at room temperature
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    Fast two-dimensional grid and transmission X-ray microscopy scanning methods for visualizing and characterizing protein crystals
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    X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex
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    Stabilizing pentacene by cyclopentannulation
    Angewandte Chemie International Edition. 2015; 54(52): 15762-15766. https://doi.org/10.1002/anie.201508650
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    Room-temperature serial crystallography at synchrotron X-ray sources using slowly flowing free-standing high-viscosity microstreams
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    Cryo-EM structure of influenza Virus RNA polymerase complex at 4.3Å resolution
    Molecular Cell. 2015; 57(5): 925-935. https://doi.org/10.1016/j.molcel.2014.12.031
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    Structural basis for the enhancement of virulence by viral spindles and their in vivo crystallization
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2015; 112(13): 3973-3978. https://doi.org/10.1073/pnas.1418798112
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    Three-dimensional mass density mapping of cellular ultrastructure by ptychographic X-ray nanotomography
    Journal of Structural Biology. 2015; 192(3): 461-469. https://doi.org/10.1016/j.jsb.2015.10.008
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    Structural analysis of the binding of type I, I1/2, and II inhibitors to Eph tyrosine kinases
    ACS Medicinal Chemistry Letters. 2015; 6(1): 79-83. https://doi.org/10.1021/ml500355x
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    Challenges and solutions for the analysis of in situ, in crystallo micro-spectrophotometric data
    Acta Crystallographica Section D: Structural Biology. 2015; 71: 27-35. https://doi.org/10.1107/S1399004714015107
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    Hydrogen bonding of the dissociated histidine ligand is not required for formation of a proximal NO adduct in cytochrome c'
    Journal of Biological Inorganic Chemistry. 2015; 20(6): 949-956. https://doi.org/10.1007/s00775-015-1278-y
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  • Grøftehauge MK, Truan D, Vasil A, Denny PW, Vasil ML, Pohl E
    Crystal structure of a hidden protein, YcaC, a putative cysteine hydrolase from Pseudomonas aeruginosa, with and without an acrylamide adduct
    International Journal of Molecular Sciences. 2015; 16(7): 15971-15984. https://doi.org/10.3390/ijms160715971
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    In meso in situ serial X-ray crystallography of soluble and membrane proteins
    Acta Crystallographica Section D: Structural Biology. 2015; 71(6): 1238-1256. https://doi.org/10.1107/S1399004715005210
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    Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
    Nature. 2015; 523: 561-567. https://doi.org/10.1038/nature14656
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    Single-crystal structure and Raman spectroscopy of synthetic titanite analog CaAlSiO4F
    Mineralogy and Petrology. 2015; 109(5): 631-641. https://doi.org/10.1007/s00710-015-0393-3
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    PRIGo: a new multi-axis goniometer for macromolecular crystallography
    Journal of Synchrotron Radiation. 2015; 22: 895-900. https://doi.org/10.1107/S1600577515005354
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    Fast native-SAD phasing for routine macromolecular structure determination
    Nature Methods. 2015; 12(2): 131-133. https://doi.org/10.1038/nmeth.3211
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    Ligand structures of synthetic deoxa-pyranosylamines with raucaffricine and strictosidine glucosidases provide structural insights into their binding and inhibitory behaviours
    Journal of Enzyme Inhibition and Medicinal Chemistry. 2015; 30(3): 472-478. https://doi.org/10.3109/14756366.2014.949252
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    Using strictosidine synthase to prepare novel alkaloids
    Current Medicinal Chemistry. 2015; 22(15): (9 pp.). https://doi.org/10.2174/0929867322666150408110919
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  • Angelaccio S, Dworkowski F, Di Bello A, Milano T, Capitani G, Pascarella S
    Conformational transitions driven by pyridoxal-5′-phosphate uptake in the psychrophilic serine hydroxymethyltransferase from Psychromonas ingrahamii
    Proteins. 2014; 82(10): 2831-2841. https://doi.org/10.1002/prot.24646
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  • Bartoloni M, Waltersperger S, Bumann M, Stocker A, Darbre T, Reymond J-L
    Stereoselective synthesis and structure determination of a bicyclo[3.3.2]decapeptide
    Arkivoc. 2014; 2014(3): 113-123. https://doi.org/10.3998/ark.5550190.p008.500
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    Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A
    Nature. 2014; 505(7481): 108-111. https://doi.org/10.1038/nature12732
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    Human cellular retinaldehyde-binding protein has secondary thermal 9-cis-retinal isomerase activity
    Journal of the American Chemical Society. 2014; 136(1): 137-146. https://doi.org/10.1021/ja411366w
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  • Campagne S, Marsh ME, Capitani G, Vorholt JA, Allain FH-T
    Structural basis for -10 promoter element melting by environmentally induced sigma factors
    Nature Structural and Molecular Biology. 2014; 21(3): 269-276. https://doi.org/10.1038/nsmb.2777
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    The M-T hook structure increases the potency of HIV-1 fusion inhibitor sifuvirtide and overcomes drug resistance
    Journal of Antimicrobial Chemotherapy. 2014; 69(10): 2759-2769. https://doi.org/10.1093/jac/dku183
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  • D'Arcy A, Bergfors T, Cowan-Jacob SW, Marsh M
    Microseed matrix screening for optimization in protein crystallization: What have we learned?
    Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 2014; 70: 1117-1126. https://doi.org/10.1107/S2053230X14015507
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    D3, the new diffractometer for the macromolecular crystallography beamlines of the Swiss Light Source
    Journal of Synchrotron Radiation. 2014; 21(2): 340-351. https://doi.org/10.1107/S160057751400006X
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    X-ray structure of the mouse serotonin 5-HT3 receptor
    Nature. 2014; 512(7514): 276-281. https://doi.org/10.1038/nature13552
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    Fingerprinting redox and ligand states in haemprotein crystal structures using resonance Raman spectroscopy
    Acta Crystallographica Section D: Structural Biology. 2014; 70(5): 1289-1296. https://doi.org/10.1107/S1399004714004039
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    Innsbruckite, Mn33(Si2O5)14(OH)38 – a new mineral from the Tyrol, Austria
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    Crystallizing membrane proteins in the lipidic mesophase. Experience with human prostaglandin E2 synthase 1 and an evolving strategy
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    Speciation of a group I intron into a lariat capping ribozyme
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    A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs
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    Structural basis of microtubule stabilization by laulimalide and peloruside A
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    A type IV translocated Legionella cysteine phytase counteracts intracellular growth restriction by phytate
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    Differential modes of peptide binding onto replicative sliding clamps from various bacterial origins
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    Structural basis for the oligomerization-state switch from a dimer to a trimer of an engineered cortexillin-1 coiled-coil variant
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    Structural and functional characterization of two alpha-synuclein strains
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    Short-peptide fusion inhibitors with high potency against wild-type and enfuvirtide-resistant HIV-1
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Associated Beamlines

Contact

Head of MX
and Group Leader
Dr. Meitian Wang
Telephone: +41 56 310 4175
E-mail: meitian.wang@psi.ch

Group Leader MX
Application
Katherine McAuley
Telephone: +41 56 310 3979
E-mail: katherine.mcauley@psi.ch

Group Leader MX Instrumentation
Wayne Glettig
Telephone: +41 56 310 5823
E-mail: wayne.glettig@psi.ch

Group Leader MX Samples
Dr. May Sharpe née Marsh
Telephone: +41 56 310 5437
E-mail: may.sharpe@psi.ch

Group Leader MX Data
Dr. Justyna Aleksandra Wojdyla
Telephone: +41 56 310 5428
E-mail: justyna.wojdyla@psi.ch