Publications

Recent publications are listed below. For an extensive overview we kindly refer you to our publication repository DORA

  • Pedrini B, Finke AD, Marsh M, Luporini P, Vallesi A, Alimenti C
    Crystal structure of the pheromone Er-13 from the ciliate Euplotes raikovi, with implications for a protein-protein association model in pheromone/receptor interactions
    Journal of Structural Biology. 2022; 214(1): 107812 (10 pp.). https://doi.org/10.1016/j.jsb.2021.107812
    DORA PSI
  • Ashton A, Augustin S, Babic A, Celcer T, Ebner SG, Egli S, et al.
    Conceptual design report on controls and science IT for the SLS 2.0 upgrade project
    Villigen PSI, Switzerland: Paul Scherrer Institut; 2021. PSI Bericht: 21-03.
    DORA PSI
  • Beale JH, Marsh ME
    Optimizing the growth of endothiapepsin crystals for serial crystallography experiments
    Journal of Visualized Experiments. 2021; 168: e61896 (30 pp.). https://doi.org/10.3791/61896
    DORA PSI
  • Braun H, Garvey T, Jörg M, Ashton A, Willmott P, Kobler R, et al.
    SLS 2.0 storage ring. Technical design report
    Villigen PSI, Switzerland: Paul Scherrer Institut; 2021. PSI Bericht: 21-02.
    DORA PSI
  • Butryn A, Simon PS, Aller P, Hinchliffe P, Massad RN, Leen G, et al.
    An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography
    Nature Communications. 2021; 12(1): 4461 (7 pp.). https://doi.org/10.1038/s41467-021-24757-7
    DORA PSI
  • Cinquino M, Fieramosca A, Mastria R, Polimeno L, Moliterni A, Olieric V, et al.
    Managing growth and dimensionality of quasi 2D perovskite single-crystalline flakes for tunable excitons orientation
    Advanced Materials. 2021; 33(48): 2102326 (9 pp.). https://doi.org/10.1002/adma.202102326
    DORA PSI
  • Collu G, Bierig T, Krebs A-S, Engilberge S, Varma N, Guixà-González R, et al.
    Chimeric single α-helical domains as rigid fusion protein connections for protein nanotechnology and structural biology
    Structure. 2021. https://doi.org/10.1016/j.str.2021.09.002
    DORA PSI
  • Dhanabalan B, Biffi G, Moliterni A, Olieric V, Giannini C, Saleh G, et al.
    Engineering the optical emission and robustness of metal-halide layered perovskites through ligand accommodation
    Advanced Materials. 2021. https://doi.org/10.1002/adma.202008004
    DORA PSI
  • Gao X, Zhu K, Qin B, Olieric V, Wang M, Cui S
    Crystal structure of SARS-CoV-2 Orf9b in complex with human TOM70 suggests unusual virus-host interactions
    Nature Communications. 2021; 12(1): 2843 (9 pp.). https://doi.org/10.1038/s41467-021-23118-8
    DORA PSI
  • Gao X, Qin B, Chen P, Zhu K, Hou P, Wojdyla JA, et al.
    Crystal structure of SARS-CoV-2 papain-like protease
    Acta Pharmaceutica Sinica B. 2021; 11(1): 237-245. https://doi.org/10.1016/j.apsb.2020.08.014
    DORA PSI
  • Gao C, Stavenhagen K, Eckmair B, McKitrick TR, Mehta AY, Matsumoto Y, et al.
    Differential recognition of oligomannose isomers by glycan-binding proteins involved in innate and adaptive immunity
    Science Advances. 2021; 7(24): eabf6834 (12 pp.). https://doi.org/10.1126/sciadv.abf6834
    DORA PSI
  • Hahn CJ, Lemaire ON, Kahnt J, Engilberge S, Wegener G, Wagner T
    Crystal structure of a key enzyme for anaerobic ethane activation
    Science. 2021; 373(6550): 118-121. https://doi.org/10.1126/science.abg1765
    DORA PSI
  • Iorio A, Roche J, Engilberge S, Coquelle N, Girard E, Sterpone F, et al.
    Biochemical, structural and dynamical studies reveal strong differences in the thermal-dependent allosteric behavior of two extremophilic lactate dehydrogenases
    Journal of Structural Biology. 2021; 213(3): 107769 (11 pp.). https://doi.org/10.1016/j.jsb.2021.107769
    DORA PSI
  • Li H, Huang C-Y, Govorunova EG, Sineshchekov OA, Yi A, Rothschild KJ, et al.
    The crystal structure of bromide-bound GtACR1 reveals a pre-activated state in the transmembrane anion tunnel
    eLife. 2021; 10: e65903 (14 pp.). https://doi.org/10.7554/eLife.65903
    DORA PSI
  • Martiel I, Beale JH, Karpik A, Huang C-Y, Vera L, Olieric N, et al.
    Versatile microporous polymer-based supports for serial macromolecular crystallography
    Acta Crystallographica Section D: Structural Biology. 2021; 77(9): 1153-1167. https://doi.org/10.1107/S2059798321007324
    DORA PSI
  • Monsarrat C, Compain G, André C, Engilberge S, Martiel I, Oliéric V, et al.
    Iterative structure-based optimization of short peptides targeting the bacterial sliding clamp
    Journal of Medicinal Chemistry. 2021; 64(23): 17063-17078. https://doi.org/10.1021/acs.jmedchem.1c00918
    DORA PSI
  • Mühlethaler T, Gioia D, Prota AE, Sharpe ME, Cavalli A, Steinmetz MO
    Comprehensive analysis of binding sites in tubulin
    Angewandte Chemie International Edition. 2021; 60(24): 13331-13342. https://doi.org/10.1002/anie.202100273
    DORA PSI
  • Nasrallah C, Cannone G, Briot J, Rottier K, Berizzi AE, Huang CY, et al.
    Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations
    Cell Reports. 2021; 36(9): 109648. https://doi.org/10.1016/j.celrep.2021.109648
    DORA PSI
  • Nass K, Bacellar C, Cirelli C, Dworkowski F, Gevorkov Y, James D, et al.
    Pink-beam serial femtosecond crystallography for accurate structure-factor determination at an X-ray free-electron laser
    IUCrJ. 2021; 8: 905-920. https://doi.org/10.1107/S2052252521008046
    DORA PSI
  • Ni X, Schröder M, Olieric V, Sharpe ME, Hernandez-Olmos V, Proschak E, et al.
    Structural insights into plasticity and discovery of remdesivir metabolite GS-441524 binding in SARS-CoV-2 macrodomain
    ACS Medicinal Chemistry Letters. 2021; 12(4): 603-609. https://doi.org/10.1021/acsmedchemlett.0c00684
    DORA PSI
  • Olatunji S, Bowen K, Huang CY, Weichert D, Singh W, Tikhonova IG, et al.
    Structural basis of the membrane intramolecular transacylase reaction responsible for lyso-form lipoprotein synthesis
    Nature Communications. 2021; 12(1): 4254 (14 pp.). https://doi.org/10.1038/s41467-021-24475-0
    DORA PSI
  • Palmerini V, Monzani S, Laurichesse Q, Loudhaief R, Mari S, Cecatiello V, et al.
    Drosophila TNFRs Grindelwald and Wengen bind Eiger with different affinities and promote distinct cellular functions
    Nature Communications. 2021; 12(1): 2070 (12 pp.). https://doi.org/10.1038/s41467-021-22080-9
    DORA PSI
  • Polimeno L, Lerario G, De Giorgi M, De Marco L, Dominici L, Todisco F, et al.
    Tuning of the Berry curvature in 2D perovskite polaritons
    Nature Nanotechnology. 2021; 16: 1349-1354. https://doi.org/10.1038/s41565-021-00977-2
    DORA PSI
  • Ramberg KO, Engilberge S, Skorek T, Crowley PB
    Facile fabrication of protein-macrocycle frameworks
    Journal of the American Chemical Society. 2021; 143(4): 1896-1907. https://doi.org/10.1021/jacs.0c10697
    DORA PSI
  • Ramos J, Laux V, Haertlein M, Boeri Erba E, McAuley KE, Forsyth VT, et al.
    Structural insights into protein folding, stability and activity using in vivo perdeuteration of hen egg-white lysozyme
    IUCrJ. 2021; 8: 372-386. https://doi.org/10.1107/S2052252521001299
    DORA PSI
  • Scott DE, Francis-Newton NJ, Marsh ME, Coyne AG, Fischer G, Moschetti T, et al.
    A small-molecule inhibitor of the BRCA2-RAD51 interaction modulates RAD51 assembly and potentiates DNA damage-induced cell death
    Cell Chemical Biology. 2021; 28(6): 835-847.e5. https://doi.org/10.1016/j.chembiol.2021.02.006
    DORA PSI
  • Sutanto F, Shaabani S, Oerlemans R, Eris D, Patil P, Hadian M, et al.
    Combining high-throughput synthesis and high-throughput protein crystallography for accelerated hit identification
    Angewandte Chemie International Edition. 2021; 60(33): 18231-18239. https://doi.org/10.1002/anie.202105584
    DORA PSI
  • Toomey B, Han X, Dong CD, Edward V, Kaminski JW, Shankar S
    Characterization of phases and orientations of micro-structured materials Using computational crystallography
    In: Shankar S, Muller R, Dunning T, Chen GH, eds. Computational materials, chemistry, and biochemistry: from bold initiatives to the last mile. In honor of William A. Goddard’s contributions to science and engineering. Springer series in materials science. Cham: Springer; 2021:213-231. https://doi.org/10.1007/978-3-030-18778-1_11
    DORA PSI
  • de Wijn R, Rollet K, Olieric V, Hennig O, Thome N, Noûs C, et al.
    Crystallization and structural determination of an enzyme: substrate complex by serial crystallography in a versatile microfluidic chip
    Journal of Visualized Experiments. 2021;(169): e61972 (15 pp.). https://doi.org/10.3791/61972
    DORA PSI
  • Assmann GM, Wang M, Diederichs K
    Making a difference in multi-data-set crystallography: simple and deterministic data-scaling/selection methods
    Acta Crystallographica Section D: Structural Biology. 2020; 76: 636-652. https://doi.org/10.1107/S2059798320006348
    DORA PSI
  • Beale JH
    Macromolecular X-ray crystallography: soon to be a road less travelled?
    Acta Crystallographica Section D: Structural Biology. 2020; 76(5): 400-405. https://doi.org/10.1107/S2059798320004660
    DORA PSI
  • Bedi RK, Huang D, Wiedmer L, Li Y, Dolbois A, Wojdyla JA, et al.
    Selectively disrupting m6A-dependent protein-RNA interactions with fragments
    ACS Chemical Biology. 2020; 15(3): 618-625. https://doi.org/10.1021/acschembio.9b00894
    DORA PSI
  • Bernstein HJ, Förster A, Bhowmick A, Brewster AS, Brockhauser S, Gelisio L, et al.
    Gold standard for macromolecular crystallography diffraction data
    IUCrJ. 2020; 7(5): 784-792. https://doi.org/10.1107/S2052252520008672
    DORA PSI
  • Bu W, Levitskaya Z, Loh ZY, Jin S, Basu S, Ero R, et al.
    Structural basis of human full-length kindlin-3 homotrimer in an auto-inhibited state
    PLoS Biology. 2020; 18(7): e3000755 (24 pp.). https://doi.org/10.1371/journal.pbio.3000755
    DORA PSI
  • Cheng R, Huang C-Y, Hennig M, Nar H, Schnapp G
    In situ crystallography as an emerging method for structure solution of membrane proteins: the case of CCR2A
    FEBS Journal. 2020; 287(5): 866-873. https://doi.org/10.1111/febs.15098
    DORA PSI
  • Cinquino M, Polimeno L, Lerario G, De Giorgi M, Moliterni A, Olieric V, et al.
    One-step synthesis at room temperature of low dimensional perovskite single crystals with high optical quality
    Journal of Luminescence. 2020; 221: 117079 (8 pp.). https://doi.org/10.1016/j.jlumin.2020.117079
    DORA PSI
  • Crack JC, Amara P, Volbeda A, Mouesca J-M, Rohac R, Pellicer Martinez MT, et al.
    Electron and proton transfers modulate DNA binding by the transcription regulator RsrR
    Journal of the American Chemical Society. 2020; 142(11): 5104-5116. https://doi.org/10.1021/jacs.9b12250
    DORA PSI
  • Engilberge S, Wagner T, Carpentier P, Girard E, Shima S
    Krypton-derivatization highlights O2-channeling in a four-electron reducing oxidase
    Chemical Communications. 2020; 56(74): 10863-10866. https://doi.org/10.1039/d0cc04557h
    DORA PSI
  • Fadini A, Reiche S, Nass K, van Thor JJ
    Applications and limits of time-to-energy mapping of protein crystal diffraction using energy-chirped polychromatic XFEL pulses
    Applied Sciences. 2020; 10(7): 2599 (18 pp.). https://doi.org/10.3390/app10072599
    DORA PSI
  • Gao X, Zhu K, Wojdyl JA, Chen P, Qin B, Li Z, et al.
    Crystal structure of the NS3-like helicase from Alongshan virus
    IUCrJ. 2020; 7(3): 375-382. https://doi.org/10.1107/S2052252520003632
    DORA PSI
  • Görlich S, Samuel AJ, Best RJ, Seidel R, Vacelet J, Leonarski FK, et al.
    Natural hybrid silica/protein superstructure at atomic resolution
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2020; 117(49): 31088-31093. https://doi.org/10.1073/pnas.2019140117
    DORA PSI
  • Huang C-Y, Meier N, Caffrey M, Wang M, Olieric V
    3D-printed holders for in meso in situ fixed-target serial X-ray crystallography
    Journal of Applied Crystallography. 2020; 53: 854-859. https://doi.org/10.1107/S1600576720002897
    DORA PSI
  • Huang C-Y, Olieric V, Caffrey M, Wang M
    In meso in situ serial X-Ray crystallography (IMISX): a protocol for membrane protein structure determination at the Swiss Light Source
    In: Perez C, Maier T, eds. Expression, purification, and structural biology of membrane proteins. Methods in molecular biology. New York: Humana; 2020:293-319. https://doi.org/10.1007/978-1-0716-0373-4_20
    DORA PSI
  • Huwald D, Duda S, Gasper R, Olieric V, Hofmann E, Hemschemeier A
    Distinctive structural properties of THB11, a pentacoordinate Chlamydomonas reinhardtii truncated hemoglobin with N- and C-terminal extensions
    Journal of Biological Inorganic Chemistry. 2020; 25: 267-283. https://doi.org/10.1007/s00775-020-01759-2
    DORA PSI
  • Karpik A, Martiel I, Kristiansen PM, Padeste C
    Fabrication of ultrathin suspended polymer membranes as supports for serial protein crystallography
    Micro and Nano Engineering. 2020; 7: 100053 (6 pp.). https://doi.org/10.1016/j.mne.2020.100053
    DORA PSI
  • Leonarski F, Mozzanica A, Brückner M, Lopez-Cuenca C, Redford S, Sala L, et al.
    JUNGFRAU detector for brighter x-ray sources: solutions for IT and data science challenges in macromolecular crystallography
    Structural Dynamics. 2020; 7(1): 014305 (13 pp.). https://doi.org/10.1063/1.5143480
    DORA PSI
  • Lučić M, Chaplin AK, Moreno-Chicano T, Dworkowski FSN, Wilson MT, Svistunenko DA, et al.
    A subtle structural change in the distal haem pocket has a remarkable effect on tuning hydrogen peroxide reactivity in dye decolourising peroxidases from Streptomyces lividans
    Dalton Transactions. 2020; 49(5): 1620-1636. https://doi.org/10.1039/c9dt04583j
    DORA PSI
  • Lučić M, Svistunenko DA, Wilson MT, Chaplin AK, Davy B, Ebrahim A, et al.
    Serial femtosecond zero dose crystallography captures a water-free distal heme site in a dye‐decolourising peroxidase to reveal a catalytic role for an arginine in FeIV=O formation
    Angewandte Chemie International Edition. 2020; 59(48): 21656-21662. https://doi.org/10.1002/anie.202008622
    DORA PSI
  • Martiel I, Huang C-Y, Villanueva-Perez P, Panepucci E, Basu S, Caffrey M, et al.
    Low-dose in situ prelocation of protein microcrystals by 2D X-ray phase-contrast imaging for serial crystallography
    IUCrJ. 2020; 7(6): 1131-1141. https://doi.org/10.1107/S2052252520013238
    DORA PSI
  • Martiel I, Buntschu D, Meier N, Gobbo A, Panepucci E, Schneider R, et al.
    The TELL automatic sample changer for macromolecular crystallography
    Journal of Synchrotron Radiation. 2020; 27: 860-863. https://doi.org/10.1107/S1600577520002416
    DORA PSI
  • Martiel I, Mozzanica A, Opara NL, Panepucci E, Leonarski F, Redford S, et al.
    X-ray fluorescence detection for serial macromolecular crystallography using a JUNGFRAU pixel detector
    Journal of Synchrotron Radiation. 2020; 27: 329-339. https://doi.org/10.1107/S1600577519016758
    DORA PSI
  • Moliterni A, Altamura D, Lassandro R, Olieric V, Ferri G, Cardarelli F, et al.
    Synthesis, crystal structure, polymorphism and microscopic luminescence properties of anthracene derivative compounds
    Acta Crystallographica Section B: Structural Science, Crystal Engineering and Materials. 2020; B76: 427-435. https://doi.org/10.1107/S2052520620004424
    DORA PSI
  • Nass K, Cheng R, Vera L, Mozzanica A, Redford S, Ozerov D, et al.
    Advances in long-wavelength native phasing at X-ray free-electron lasers
    IUCrJ. 2020; 7: 965-975. https://doi.org/10.1107/S2052252520011379
    DORA PSI
  • Nass K, Redecke L, Perbandt M, Yefanov O, Klinge M, Koopmann R, et al.
    In cellulo crystallization of Trypanosoma brucei IMP dehydrogenase enables the identification of genuine co-factors
    Nature Communications. 2020; 11(1): 620 (13 pp.). https://doi.org/10.1038/s41467-020-14484-w
    DORA PSI
  • Nass K
    Pixel modelling - a new age in SFX data analysis
    IUCrJ. 2020; 7: 949-950. https://doi.org/10.1107/S2052252520014281
    DORA PSI
  • Olatunji S, Yu X, Bailey J, Huang C-Y, Zapotoczna M, Bowen K, et al.
    Structures of lipoprotein signal peptidase II from Staphylococcus aureus complexed with antibiotics globomycin and myxovirescin
    Nature Communications. 2020; 11(1): 140 (11 pp.). https://doi.org/10.1038/s41467-019-13724-y
    DORA PSI
  • Pfanzagl V, Beale JH, Michlits H, Schmidt D, Gabler T, Obinger C, et al.
    X-ray-induced photoreduction of heme metal centers rapidly induces active-site perturbations in a protein-independent manner
    Journal of Biological Chemistry. 2020; 295(39): 13488-13501. https://doi.org/10.1074/jbc.ra120.014087
    DORA PSI
  • Prat E, Abela R, Aiba M, Alarcon A, Alex J, Arbelo Y, et al.
    A compact and cost-effective hard X-ray free-electron laser driven by a high-brightness and low-energy electron beam
    Nature Photonics. 2020; 14: 748-754. https://doi.org/10.1038/s41566-020-00712-8
    DORA PSI
  • Skopintsev P, Ehrenberg D, Weinert T, James D, Kar RK, Johnson PJM, et al.
    Femtosecond-to-millisecond structural changes in a light-driven sodium pump
    Nature. 2020; 583: 314-318. https://doi.org/10.1038/s41586-020-2307-8
    DORA PSI
  • Soman A, Liew CW, Teo HL, Berezhnoy NV, Olieric V, Korolev N, et al.
    The human telomeric nucleosome displays distinct structural and dynamic properties
    Nucleic Acids Research. 2020; 48(10): 5383-5396. https://doi.org/10.1093/nar/gkaa289
    DORA PSI
  • Steib E, Laporte MH, Gambarotto D, Olieric N, Zheng C, Borgers S, et al.
    WDR90 is a centriolar microtubule wall protein important for centriole architecture integrity
    eLife. 2020; 9: e57205 (28 pp.). https://doi.org/10.7554/ELIFE.57205
    DORA PSI
  • Tsujino S, Tomizaki T
    Applications of acoustic levitation in chemical analysis and biochemistry
    In: Zang D, ed. Acoustic levitation. From physics to applications. Singapore: Springer; 2020:151-179. https://doi.org/10.1007/978-981-32-9065-5_9
    DORA PSI
  • Tsujino S, Tomizaki T, Kepa MW
    On-demand droplet loading of ultrasonic acoustic levitator with small droplets for protein crystallography application
    In: Proceedings of the 2020 IEEE international ultrasonics symposium (IUS). IEEE symposium (IUS) ultrasonics. sine loco: IEEE; 2020:9251627 (3 pp.). https://doi.org/10.1109/IUS46767.2020.9251627
    DORA PSI
  • Ye F, Wang C, Fu Q, Yan X-F, Bharath SR, Casanas A, et al.
    Structural basis of a novel repressor, SghR, controlling Agrobacterium infection by cross-talking to plants
    Journal of Biological Chemistry. 2020; 295(34): 12290-12304. https://doi.org/10.1074/jbc.RA120.012908
    DORA PSI
  • Yu X, Gao X, Zhu K, Yin H, Mao X, Wojdyla JA, et al.
    Characterization of a toxin-antitoxin system in Mycobacterium tuberculosis suggests neutralization by phosphorylation as the antitoxicity mechanism
    Communications Biology. 2020; 3(1): 216 (15 pp.). https://doi.org/10.1038/s42003-020-0941-1
    DORA PSI
  • André C, Martiel I, Wolff P, Landolfo M, Lorber B, Silva da Veiga C, et al.
    Interaction of a model peptide on gram negative and gram positive bacterial sliding clamps
    ACS Infectious Diseases. 2019; 5: 1022-1034. https://doi.org/10.1021/acsinfecdis.9b00089
    DORA PSI
  • Apel A-K, Cheng RKY, Tautermann CS, Brauchle M, Huang C-Y, Pautsch A, et al.
    Crystal structure of CC chemokine receptor 2A in complex with an orthosteric antagonist provides insights for the design of selective antagonists
    Structure. 2019; 27(3): 427-438.e5. https://doi.org/10.1016/j.str.2018.10.027
    DORA PSI
  • Basu S, Kaminski JW, Panepucci E, Huang C-Y, Warshamanage R, Wang M, et al.
    Automated data collection and real-time data analysis suite for serial synchrotron crystallography
    Journal of Synchrotron Radiation. 2019; 26(1): 244-252. https://doi.org/10.1107/S1600577518016570
    DORA PSI
  • Basu S, Olieric V, Leonarski F, Matsugaki N, Kawano Y, Takashi T, et al.
    Long-wavelength native-SAD phasing: opportunities and challenges
    IUCrJ. 2019; 6(3): 1-14. https://doi.org/10.1107/S2052252519002756
    DORA PSI
  • Basu S, Finke A, Vera L, Wang M, Olieric V
    Making routine native SAD a reality: lessons from beamline X06DA at the Swiss Light Source
    Acta Crystallographica Section D: Structural Biology. 2019; 75(3): 262-271. https://doi.org/10.1107/S2059798319003103
    DORA PSI
  • Casadei CM, Nass K, Barty A, Hunter MS, Padeste C, Tsai C-J, et al.
    Structure-factor amplitude reconstruction from serial femtosecond crystallography of two-dimensional membrane-protein crystals
    IUCrJ. 2019; 6: 34-45. https://doi.org/10.1107/S2052252518014641
    DORA PSI
  • Galuskin EV, Krüger B, Galuskina IO, Krüger H, Vapnik Y, Pauluhn A, et al.
    Levantite, KCa3(Al2Si3)O11(PO4), a new latiumite group mineral from pyrometamorphic rock of the Hatrurim Basin, Negev Desert, Israel
    Mineralogical Magazine. 2019; 83(5): 713-721. https://doi.org/10.1180/mgm.2019.37
    DORA PSI
  • Jaeger K, Bruenle S, Weinert T, Guba W, Muehle J, Miyazaki T, et al.
    Structural basis for allosteric ligand recognition in the human CC chemokine receptor 7
    Cell. 2019; 178(5): 1222-1230. https://doi.org/10.1016/j.cell.2019.07.028
    DORA PSI
  • Jensen SC, Sullivan B, Hartzler DA, Aguilar JM, Awel S, Bajt S, et al.
    X-ray emission spectroscopy at X-ray free electron lasers: limits to observation of the classical spectroscopic response for electronic structure analysis
    Journal of Physical Chemistry Letters. 2019; 10(3): 441-446. https://doi.org/10.1021/acs.jpclett.8b03595
    DORA PSI
  • Kahlenberg V, Galuskina I, Krüger B, Pauluhn A, Galuskin E
    Structural investigations on bredigite from the Hatrurim Complex
    Mineralogy and Petrology. 2019; 113(2): 261-272. https://doi.org/10.1007/s00710-018-0646-z
    DORA PSI
  • Kahlenberg V, Albrecht R, Schmidmair D, Krüger H, Krüger B, Tribus M, et al.
    Structural studies on Ca3Al4MgO10 (C3A2M) - a ternary phase in the system CaO-Al2O3-MgO
    Journal of the American Ceramic Society. 2019; 102(4): 2084-2093. https://doi.org/10.1111/jace.16001
    DORA PSI
  • Leonarski F, D’Ascenzo L, Auffinger P
    Nucleobase carbonyl groups are poor Mg2+ inner-sphere binders but excellent monovalent ion binders - a critical PDB survey
    RNA. 2019; 25(11): 173-192. https://doi.org/10.1261/rna.068437.118
    DORA PSI
  • Li H, Huang C-Y, Govorunova EG, Schafer CT, Sineshchekov OA, Wang M, et al.
    Crystal structure of a natural light-gated anion channelrhodopsin
    eLife. 2019; 8: e41741 (21 pp.). https://doi.org/10.7554/eLife.41741
    DORA PSI
  • Liu X, An T, Li D, Fan Z, Xiang P, Li C, et al.
    Structure of the heterophilic interaction between the nectin-like 4 and nectin-like 1 molecules
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2019; 116(6): 2068-2077. https://doi.org/10.1073/pnas.1810969116
    DORA PSI
  • Makita M, Vartiainen I, Mohacsi I, Caleman C, Diaz A, Jönsson HO, et al.
    Femtosecond phase-transition in hard x-ray excited bismuth
    Scientific Reports. 2019; 9(1): 602 (7 pp.). https://doi.org/10.1038/s41598-018-36216-3
    DORA PSI
  • Martiel I, Müller-Werkmeister HM, Cohen AE
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  • Dworkowski FSN, Hough MA, Pompidor G, Fuchs MR
    Challenges and solutions for the analysis of in situ, in crystallo micro-spectrophotometric data
    Acta Crystallographica Section D: Structural Biology. 2015; 71: 27-35. https://doi.org/10.1107/S1399004714015107
    DORA PSI
  • Ghafoor DD, Kekilli D, Abdullah GH, Dworkowski FSN, Hassan HG, Wilson MT, et al.
    Hydrogen bonding of the dissociated histidine ligand is not required for formation of a proximal NO adduct in cytochrome c'
    Journal of Biological Inorganic Chemistry. 2015; 20(6): 949-956. https://doi.org/10.1007/s00775-015-1278-y
    DORA PSI
  • Grøftehauge MK, Truan D, Vasil A, Denny PW, Vasil ML, Pohl E
    Crystal structure of a hidden protein, YcaC, a putative cysteine hydrolase from Pseudomonas aeruginosa, with and without an acrylamide adduct
    International Journal of Molecular Sciences. 2015; 16(7): 15971-15984. https://doi.org/10.3390/ijms160715971
    DORA PSI
  • Huang C-Y, Olieric V, Ma P, Panepucci E, Diederichs K, Wang M, et al.
    In meso in situ serial X-ray crystallography of soluble and membrane proteins
    Acta Crystallographica Section D: Structural Biology. 2015; 71(6): 1238-1256. https://doi.org/10.1107/S1399004715005210
    DORA PSI
  • Kang Y, Zhou XE, Gao X, He Y, Liu W, Ishchenko A, et al.
    Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
    Nature. 2015; 523: 561-567. https://doi.org/10.1038/nature14656
    DORA PSI
  • Krüger H, Többens DM, Tropper P, Haefeker U, Kahlenberg V, Fuchs MR, et al.
    Single-crystal structure and Raman spectroscopy of synthetic titanite analog CaAlSiO4F
    Mineralogy and Petrology. 2015; 109(5): 631-641. https://doi.org/10.1007/s00710-015-0393-3
    DORA PSI
  • Waltersperger S, Olieric V, Pradervand C, Glettig W, Salathe M, Fuchs MR, et al.
    PRIGo: a new multi-axis goniometer for macromolecular crystallography
    Journal of Synchrotron Radiation. 2015; 22: 895-900. https://doi.org/10.1107/S1600577515005354
    DORA PSI
  • Weinert T, Olieric V, Waltersperger S, Panepucci E, Chen L, Zhang H, et al.
    Fast native-SAD phasing for routine macromolecular structure determination
    Nature Methods. 2015; 12(2): 131-133. https://doi.org/10.1038/nmeth.3211
    DORA PSI
  • Xia L, Lin H, Staniek A, Panjikar S, Ruppert M, Hilgers P, et al.
    Ligand structures of synthetic deoxa-pyranosylamines with raucaffricine and strictosidine glucosidases provide structural insights into their binding and inhibitory behaviours
    Journal of Enzyme Inhibition and Medicinal Chemistry. 2015; 30(3): 472-478. https://doi.org/10.3109/14756366.2014.949252
    DORA PSI
  • Zhu H, Kerčmar P, Wu F, Rajendran C, Sun L, Wang M, et al.
    Using strictosidine synthase to prepare novel alkaloids
    Current Medicinal Chemistry. 2015; 22(15): (9 pp.). https://doi.org/10.2174/0929867322666150408110919
    DORA PSI
  • Angelaccio S, Dworkowski F, Di Bello A, Milano T, Capitani G, Pascarella S
    Conformational transitions driven by pyridoxal-5′-phosphate uptake in the psychrophilic serine hydroxymethyltransferase from Psychromonas ingrahamii
    Proteins. 2014; 82(10): 2831-2841. https://doi.org/10.1002/prot.24646
    DORA PSI
  • Bartoloni M, Waltersperger S, Bumann M, Stocker A, Darbre T, Reymond J-L
    Stereoselective synthesis and structure determination of a bicyclo[3.3.2]decapeptide
    Arkivoc. 2014; 2014(3): 113-123. https://doi.org/10.3998/ark.5550190.p008.500
    DORA PSI
  • Benoit RM, Frey D, Hilbert M, Kevenaar JT, Wieser MM, Stirnimann CU, et al.
    Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A
    Nature. 2014; 505(7481): 108-111. https://doi.org/10.1038/nature12732
    DORA PSI
  • Bolze CS, Helbling RE, Owen RL, Pearson AR, Pompidor G, Dworkowski F, et al.
    Human cellular retinaldehyde-binding protein has secondary thermal 9-cis-retinal isomerase activity
    Journal of the American Chemical Society. 2014; 136(1): 137-146. https://doi.org/10.1021/ja411366w
    DORA PSI
  • Campagne S, Marsh ME, Capitani G, Vorholt JA, Allain FH-T
    Structural basis for -10 promoter element melting by environmentally induced sigma factors
    Nature Structural and Molecular Biology. 2014; 21(3): 269-276. https://doi.org/10.1038/nsmb.2777
    DORA PSI
  • Chong H, Yao X, Qiu Z, Sun J, Qiao Y, Zhang M, et al.
    The M-T hook structure increases the potency of HIV-1 fusion inhibitor sifuvirtide and overcomes drug resistance
    Journal of Antimicrobial Chemotherapy. 2014; 69(10): 2759-2769. https://doi.org/10.1093/jac/dku183
    DORA PSI
  • D'Arcy A, Bergfors T, Cowan-Jacob SW, Marsh M
    Microseed matrix screening for optimization in protein crystallization: What have we learned?
    Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 2014; 70: 1117-1126. https://doi.org/10.1107/S2053230X14015507
    DORA PSI
  • Fuchs MR, Pradervand C, Thominet V, Schneider R, Panepucci E, Grunder M, et al.
    D3, the new diffractometer for the macromolecular crystallography beamlines of the Swiss Light Source
    Journal of Synchrotron Radiation. 2014; 21(2): 340-351. https://doi.org/10.1107/S160057751400006X
    DORA PSI
  • Hassaine G, Deluz C, Grasso L, Wyss R, Tol MB, Hovius R, et al.
    X-ray structure of the mouse serotonin 5-HT3 receptor
    Nature. 2014; 512(7514): 276-281. https://doi.org/10.1038/nature13552
    DORA PSI
  • Kekilli D, Dworkowski FSN, Pompidor G, Fuchs MR, Andrew CR, Antonyuk S, et al.
    Fingerprinting redox and ligand states in haemprotein crystal structures using resonance Raman spectroscopy
    Acta Crystallographica Section D: Structural Biology. 2014; 70(5): 1289-1296. https://doi.org/10.1107/S1399004714004039
    DORA PSI
  • Krüger H, Tropper P, Haefeker U, Kaindl R, Tribus M, Kahlenberg V, et al.
    Innsbruckite, Mn33(Si2O5)14(OH)38 – a new mineral from the Tyrol, Austria
    Mineralogical Magazine. 2014; 78(7): 1613-1627. https://doi.org/10.1180/minmag.2014.078.7.06
    DORA PSI
  • Li D, Howe N, Dukkipati A, Shah STA, Bax BD, Edge C, et al.
    Crystallizing membrane proteins in the lipidic mesophase. Experience with human prostaglandin E2 synthase 1 and an evolving strategy
    Crystal Growth and Design. 2014; 14(4): 2034-2047. https://doi.org/10.1021/cg500157x
    DORA PSI
  • Meyer M, Nielsen H, Oliéric V, Roblin P, Johansen SD, Westhof E, et al.
    Speciation of a group I intron into a lariat capping ribozyme
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2014; 111(21): 7659-7664. https://doi.org/10.1073/pnas.1322248111
    DORA PSI
  • Prota AE, Bargsten K, Diaz JF, Marsh M, Cuevas C, Liniger M, et al.
    A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2014; 111(38): 13817-13821. https://doi.org/10.1073/pnas.1408124111
    DORA PSI
  • Prota AE, Bargsten K, Northcote PT, Marsh M, Altmann K-H, Miller JH, et al.
    Structural basis of microtubule stabilization by laulimalide and peloruside A
    Angewandte Chemie International Edition. 2014; 53(6): 1621-1625. https://doi.org/10.1002/anie.201307749
    DORA PSI
  • Weber S, Stirnimann CU, Wieser M, Frey D, Meier R, Engelhardt S, et al.
    A type IV translocated Legionella cysteine phytase counteracts intracellular growth restriction by phytate
    Journal of Biological Chemistry. 2014; 289(49): 34175-34188. https://doi.org/10.1074/jbc.M114.592568
    DORA PSI
  • Wolff P, Amal I, Oliéric V, Chaloin O, Gygli G, Ennifar E, et al.
    Differential modes of peptide binding onto replicative sliding clamps from various bacterial origins
    Journal of Medicinal Chemistry. 2014; 57(18): 7565-7576. https://doi.org/10.1021/jm500467a
    DORA PSI
  • Bjelić S, Wieser M, Frey D, Stirnimann CU, Chance MR, Jaussi R, et al.
    Structural basis for the oligomerization-state switch from a dimer to a trimer of an engineered cortexillin-1 coiled-coil variant
    PLoS One. 2013; 8(5): e63370 (7 pp.). https://doi.org/10.1371/journal.pone.0063370
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  • Bousset L, Pieri L, Ruiz-Arlandis G, Gath J, Jensen PH, Habenstein B, et al.
    Structural and functional characterization of two alpha-synuclein strains
    Nature Communications. 2013; 4: 2575 (13 pp.). https://doi.org/10.1038/ncomms3575
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  • Chong H, Yao X, Qiu Z, Sun J, Zhang M, Waltersperger S, et al.
    Short-peptide fusion inhibitors with high potency against wild-type and enfuvirtide-resistant HIV-1
    FASEB Journal. 2013; 27(3): 1203-1213. https://doi.org/10.1096/fj.12-222547
    DORA PSI
  • Feng S, Chen Y, Kamada K, Wang H, Tang K, Wang M, et al.
    YoeB-ribosome structure: a canonical RNase that requires the ribosome for its specific activity
    Nucleic Acids Research. 2013; 41(20): 9549-9556. https://doi.org/10.1093/nar/gkt742
    DORA PSI
  • Gao Y, Ran T, Marsh M, Zhu W, Wang M, Mao X, et al.
    Crystal structures of Cg1458 reveal a catalytic lid domain and a common catalytic mechanism for the FAH family
    Biochemical Journal. 2013; 449(1): 51-60. https://doi.org/10.1042/BJ20120913
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  • Gao X, Zou T, Mu Z, Qin B, Yang J, Waltersperger S, et al.
    Structural insights into VirB-DNA complexes reveal mechanism of transcriptional activation of virulence genes
    Nucleic Acids Research. 2013; 41(22): 10529-10541. https://doi.org/10.1093/nar/gkt748
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  • Merlino A, Fuchs MR, Pica A, Balsamo A, Dworkowski FSN, Pompidor G, et al.
    Selective X-ray-induced NO photodissociation in haemoglobin crystals: evidence from a Raman-assisted crystallographic study
    Acta Crystallographica Section D: Structural Biology. 2013; 69(1): 137-140. https://doi.org/10.1107/S0907444912042229
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  • Pinker F, Brun M, Morin P, Deman A-L, Chateaux J-F, Oliéric V, et al.
    ChipX: a novel microfluidic chip for counter-diffusion crystallization of biomolecules and in situ crystal analysis at room temperature
    Crystal Growth and Design. 2013; 13(8): 3333-3340. https://doi.org/10.1021/CG301757G
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  • Pompidor G, Dworkowski FSN, Thominet V, Schulze-Briese C, Fuchs MR
    A new on-axis micro-spectrophotometer for combining Raman, fluorescence and UV/Vis absorption spectroscopy with macromolecular crystallography at the Swiss Light Source
    Journal of Synchrotron Radiation. 2013; 20(5): 765-776. https://doi.org/10.1107/S0909049513016063
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  • Schacherl M, Waltersperger S, Baumann U
    Structural characterization of the ribonuclease H-like type ASKHA superfamily kinase MK0840 from Methanopyrus kandleri
    Acta Crystallographica Section D: Structural Biology. 2013; 69(12): 2440-2450. https://doi.org/10.1107/S0907444913022683
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  • Truan D, Vasil A, Stonehouse M, Vasil ML, Pohl E
    High-level over-expression, purification, and crystallization of a novel phospholipase C/sphingomyelinase from Pseudomonas aeruginosa
    Protein Expression and Purification. 2013; 90(1): 40-46. https://doi.org/10.1016/j.pep.2012.11.005
    DORA PSI
  • Wu M, Tong S, Waltersperger S, Diederichs K, Wang M, Zheng L
    Crystal structure of Ca2+/H+ antiporter protein YfkE reveals the mechanisms of Ca2+ efflux and its pH regulation
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2013; 110(28): 11367-11372. https://doi.org/10.1073/pnas.1302515110
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  • Xia L, Rajendran C, Ruppert M, Panjikar S, Wang M, Stoeckigt J
    High speed X-ray analysis of plant enzymes at room temperature
    Phytochemistry. 2013; 91: 88-92. https://doi.org/10.1016/j.phytochem.2012.05.009
    DORA PSI

Associated Beamlines

Contact

Head of MX
and Group Leader
Dr. Meitian Wang
Telephone: +41 56 310 4175
E-mail: meitian.wang@psi.ch

Group Leader MX
Application
Katherine McAuley
Telephone: +41 56 310 3979
E-mail: katherine.mcauley@psi.ch

Group Leader MX Instrumentation
Wayne Glettig
Telephone: +41 56 310 5823
E-mail: wayne.glettig@psi.ch

Group Leader MX Samples
Dr. May Sharpe née Marsh
Telephone: +41 56 310 5437
E-mail: may.sharpe@psi.ch

Group Leader MX Data
Dr. Justyna Aleksandra Wojdyla
Telephone: +41 56 310 5428
E-mail: justyna.wojdyla@psi.ch