Publications

Recent publications are listed below. For an extensive overview we kindly refer you to our publication repository DORA

  • Assmann GM, Wang M, Diederichs K
    Making a difference in multi-data-set crystallography: simple and deterministic data-scaling/selection methods
    Acta Crystallographica Section D: Structural Biology. 2020; 76: 636-652. https://doi.org/10.1107/S2059798320006348
    DORA PSI
  • Beale JH
    Macromolecular X-ray crystallography: soon to be a road less travelled?
    Acta Crystallographica Section D: Structural Biology. 2020; 76(5): 400-405. https://doi.org/10.1107/S2059798320004660
    DORA PSI
  • Bedi RK, Huang D, Wiedmer L, Li Y, Dolbois A, Wojdyla JA, et al.
    Selectively disrupting m6A-dependent protein-RNA interactions with fragments
    ACS Chemical Biology. 2020; 15(3): 618-625. https://doi.org/10.1021/acschembio.9b00894
    DORA PSI
  • Bernstein HJ, Förster A, Bhowmick A, Brewster AS, Brockhauser S, Gelisio L, et al.
    Gold standard for macromolecular crystallography diffraction data
    IUCrJ. 2020; 7(5): 784-792. https://doi.org/10.1107/S2052252520008672
    DORA PSI
  • Bu W, Levitskaya Z, Loh ZY, Jin S, Basu S, Ero R, et al.
    Structural basis of human full-length kindlin-3 homotrimer in an auto-inhibited state
    PLoS Biology. 2020; 18(7): e3000755 (24 pp.). https://doi.org/10.1371/journal.pbio.3000755
    DORA PSI
  • Cheng R, Huang C-Y, Hennig M, Nar H, Schnapp G
    In situ crystallography as an emerging method for structure solution of membrane proteins: the case of CCR2A
    FEBS Journal. 2020; 287(5): 866-873. https://doi.org/10.1111/febs.15098
    DORA PSI
  • Cinquino M, Polimeno L, Lerario G, De Giorgi M, Moliterni A, Olieric V, et al.
    One-step synthesis at room temperature of low dimensional perovskite single crystals with high optical quality
    Journal of Luminescence. 2020; 221: 117079 (8 pp.). https://doi.org/10.1016/j.jlumin.2020.117079
    DORA PSI
  • Crack JC, Amara P, Volbeda A, Mouesca J-M, Rohac R, Pellicer Martinez MT, et al.
    Electron and proton transfers modulate DNA binding by the transcription regulator RsrR
    Journal of the American Chemical Society. 2020; 142(11): 5104-5116. https://doi.org/10.1021/jacs.9b12250
    DORA PSI
  • Engilberge S, Wagner T, Carpentier P, Girard E, Shima S
    Krypton-derivatization highlights O2-channeling in a four-electron reducing oxidase
    Chemical Communications. 2020; 56(74): 10863-10866. https://doi.org/10.1039/d0cc04557h
    DORA PSI
  • Fadini A, Reiche S, Nass K, van Thor JJ
    Applications and limits of time-to-energy mapping of protein crystal diffraction using energy-chirped polychromatic XFEL pulses
    Applied Sciences. 2020; 10(7): 2599 (18 pp.). https://doi.org/10.3390/app10072599
    DORA PSI
  • Gao X, Qin B, Chen P, Zhu K, Hou P, Wojdyla JA, et al.
    Crystal structure of SARS-CoV-2 papain-like protease
    Acta Pharmaceutica Sinica B. 2020: (9 pp.). https://doi.org/10.1016/j.apsb.2020.08.014
    DORA PSI
  • Gao X, Zhu K, Wojdyl JA, Chen P, Qin B, Li Z, et al.
    Crystal structure of the NS3-like helicase from Alongshan virus
    IUCrJ. 2020; 7(3): 375-382. https://doi.org/10.1107/S2052252520003632
    DORA PSI
  • Görlich S, Samuel AJ, Best RJ, Seidel R, Vacelet J, Leonarski FK, et al.
    Natural hybrid silica/protein superstructure at atomic resolution
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2020; 117(49): 31088-31093. https://doi.org/10.1073/pnas.2019140117
    DORA PSI
  • Huang C-Y, Meier N, Caffrey M, Wang M, Olieric V
    3D-printed holders for in meso in situ fixed-target serial X-ray crystallography
    Journal of Applied Crystallography. 2020; 53: 854-859. https://doi.org/10.1107/S1600576720002897
    DORA PSI
  • Huang C-Y, Olieric V, Caffrey M, Wang M
    In meso in situ serial X-Ray crystallography (IMISX): a protocol for membrane protein structure determination at the Swiss Light Source
    In: Perez C, Maier T, eds. Expression, purification, and structural biology of membrane proteins. Methods in molecular biology. New York: Humana; 2020:293-319. https://doi.org/10.1007/978-1-0716-0373-4_20
    DORA PSI
  • Huwald D, Duda S, Gasper R, Olieric V, Hofmann E, Hemschemeier A
    Distinctive structural properties of THB11, a pentacoordinate Chlamydomonas reinhardtii truncated hemoglobin with N- and C-terminal extensions
    Journal of Biological Inorganic Chemistry. 2020; 25: 267-283. https://doi.org/10.1007/s00775-020-01759-2
    DORA PSI
  • Karpik A, Martiel I, Kristiansen PM, Padeste C
    Fabrication of ultrathin suspended polymer membranes as supports for serial protein crystallography
    Micro and Nano Engineering. 2020; 7: 100053 (6 pp.). https://doi.org/10.1016/j.mne.2020.100053
    DORA PSI
  • Leonarski F, Mozzanica A, Brückner M, Lopez-Cuenca C, Redford S, Sala L, et al.
    JUNGFRAU detector for brighter x-ray sources: solutions for IT and data science challenges in macromolecular crystallography
    Structural Dynamics. 2020; 7(1): 014305 (13 pp.). https://doi.org/10.1063/1.5143480
    DORA PSI
  • Lučić M, Chaplin AK, Moreno-Chicano T, Dworkowski FSN, Wilson MT, Svistunenko DA, et al.
    A subtle structural change in the distal haem pocket has a remarkable effect on tuning hydrogen peroxide reactivity in dye decolourising peroxidases from Streptomyces lividans
    Dalton Transactions. 2020; 49(5): 1620-1636. https://doi.org/10.1039/c9dt04583j
    DORA PSI
  • Lučić M, Svistunenko DA, Wilson MT, Chaplin AK, Davy B, Ebrahim A, et al.
    Serial femtosecond zero dose crystallography captures a water-free distal heme site in a dye‐decolourising peroxidase to reveal a catalytic role for an arginine in FeIV=O formation
    Angewandte Chemie International Edition. 2020. https://doi.org/10.1002/anie.202008622
    DORA PSI
  • Martiel I, Huang C-Y, Villanueva-Perez P, Panepucci E, Basu S, Caffrey M, et al.
    Low-dose in situ prelocation of protein microcrystals by 2D X-ray phase-contrast imaging for serial crystallography
    IUCrJ. 2020; 7(6): 1131-1141. https://doi.org/10.1107/S2052252520013238
    DORA PSI
  • Martiel I, Buntschu D, Meier N, Gobbo A, Panepucci E, Schneider R, et al.
    The TELL automatic sample changer for macromolecular crystallography
    Journal of Synchrotron Radiation. 2020; 27: 860-863. https://doi.org/10.1107/S1600577520002416
    DORA PSI
  • Martiel I, Mozzanica A, Opara NL, Panepucci E, Leonarski F, Redford S, et al.
    X-ray fluorescence detection for serial macromolecular crystallography using a JUNGFRAU pixel detector
    Journal of Synchrotron Radiation. 2020; 27: 329-339. https://doi.org/10.1107/S1600577519016758
    DORA PSI
  • Moliterni A, Altamura D, Lassandro R, Olieric V, Ferri G, Cardarelli F, et al.
    Synthesis, crystal structure, polymorphism and microscopic luminescence properties of anthracene derivative compounds
    Acta Crystallographica Section B: Structural Science, Crystal Engineering and Materials. 2020; B76: 427-435. https://doi.org/10.1107/S2052520620004424
    DORA PSI
  • Nass K, Cheng R, Vera L, Mozzanica A, Redford S, Ozerov D, et al.
    Advances in long-wavelength native phasing at X-ray free-electron lasers
    IUCrJ. 2020; 7: 965-975. https://doi.org/10.1107/S2052252520011379
    DORA PSI
  • Nass K, Redecke L, Perbandt M, Yefanov O, Klinge M, Koopmann R, et al.
    In cellulo crystallization of Trypanosoma brucei IMP dehydrogenase enables the identification of genuine co-factors
    Nature Communications. 2020; 11(1): 620 (13 pp.). https://doi.org/10.1038/s41467-020-14484-w
    DORA PSI
  • Nass K
    Pixel modelling - a new age in SFX data analysis
    IUCrJ. 2020; 7: 949-950. https://doi.org/10.1107/S2052252520014281
    DORA PSI
  • Olatunji S, Yu X, Bailey J, Huang C-Y, Zapotoczna M, Bowen K, et al.
    Structures of lipoprotein signal peptidase II from Staphylococcus aureus complexed with antibiotics globomycin and myxovirescin
    Nature Communications. 2020; 11(1): 140 (11 pp.). https://doi.org/10.1038/s41467-019-13724-y
    DORA PSI
  • Pfanzagl V, Beale JH, Michlits H, Schmidt D, Gabler T, Obinger C, et al.
    X-ray-induced photoreduction of heme metal centers rapidly induces active-site perturbations in a protein-independent manner
    Journal of Biological Chemistry. 2020; 295(39): 13488-13501. https://doi.org/10.1074/jbc.ra120.014087
    DORA PSI
  • Prat E, Abela R, Aiba M, Alarcon A, Alex J, Arbelo Y, et al.
    A compact and cost-effective hard X-ray free-electron laser driven by a high-brightness and low-energy electron beam
    Nature Photonics. 2020; 14: 748-754. https://doi.org/10.1038/s41566-020-00712-8
    DORA PSI
  • Skopintsev P, Ehrenberg D, Weinert T, James D, Kar RK, Johnson PJM, et al.
    Femtosecond-to-millisecond structural changes in a light-driven sodium pump
    Nature. 2020; 583: 314-318. https://doi.org/10.1038/s41586-020-2307-8
    DORA PSI
  • Soman A, Liew CW, Teo HL, Berezhnoy NV, Olieric V, Korolev N, et al.
    The human telomeric nucleosome displays distinct structural and dynamic properties
    Nucleic Acids Research. 2020; 48(10): 5383-5396. https://doi.org/10.1093/nar/gkaa289
    DORA PSI
  • Steib E, Laporte MH, Gambarotto D, Olieric N, Zheng C, Borgers S, et al.
    WDR90 is a centriolar microtubule wall protein important for centriole architecture integrity
    eLife. 2020; 9: e57205 (28 pp.). https://doi.org/10.7554/ELIFE.57205
    DORA PSI
  • Tsujino S, Tomizaki T
    Applications of acoustic levitation in chemical analysis and biochemistry
    In: Zang D, ed. Acoustic levitation. From physics to applications. Singapore: Springer; 2020:151-179. https://doi.org/10.1007/978-981-32-9065-5_9
    DORA PSI
  • Ye F, Wang C, Fu Q, Yan X-F, Bharath SR, Casanas A, et al.
    Structural basis of a novel repressor, SghR, controlling Agrobacterium infection by cross-talking to plants
    Journal of Biological Chemistry. 2020; 295(34): 12290-12304. https://doi.org/10.1074/jbc.RA120.012908
    DORA PSI
  • Yu X, Gao X, Zhu K, Yin H, Mao X, Wojdyla JA, et al.
    Characterization of a toxin-antitoxin system in Mycobacterium tuberculosis suggests neutralization by phosphorylation as the antitoxicity mechanism
    Communications Biology. 2020; 3(1): 216 (15 pp.). https://doi.org/10.1038/s42003-020-0941-1
    DORA PSI
  • André C, Martiel I, Wolff P, Landolfo M, Lorber B, Silva da Veiga C, et al.
    Interaction of a model peptide on gram negative and gram positive bacterial sliding clamps
    ACS Infectious Diseases. 2019; 5: 1022-1034. https://doi.org/10.1021/acsinfecdis.9b00089
    DORA PSI
  • Apel A-K, Cheng RKY, Tautermann CS, Brauchle M, Huang C-Y, Pautsch A, et al.
    Crystal structure of CC chemokine receptor 2A in complex with an orthosteric antagonist provides insights for the design of selective antagonists
    Structure. 2019; 27(3): 427-438.e5. https://doi.org/10.1016/j.str.2018.10.027
    DORA PSI
  • Basu S, Kaminski JW, Panepucci E, Huang C-Y, Warshamanage R, Wang M, et al.
    Automated data collection and real-time data analysis suite for serial synchrotron crystallography
    Journal of Synchrotron Radiation. 2019; 26(1): 244-252. https://doi.org/10.1107/S1600577518016570
    DORA PSI
  • Basu S, Olieric V, Leonarski F, Matsugaki N, Kawano Y, Takashi T, et al.
    Long-wavelength native-SAD phasing: opportunities and challenges
    IUCrJ. 2019; 6(3): 1-14. https://doi.org/10.1107/S2052252519002756
    DORA PSI
  • Basu S, Finke A, Vera L, Wang M, Olieric V
    Making routine native SAD a reality: lessons from beamline X06DA at the Swiss Light Source
    Acta Crystallographica Section D: Structural Biology. 2019; 75(3): 262-271. https://doi.org/10.1107/S2059798319003103
    DORA PSI
  • Casadei CM, Nass K, Barty A, Hunter MS, Padeste C, Tsai C-J, et al.
    Structure-factor amplitude reconstruction from serial femtosecond crystallography of two-dimensional membrane-protein crystals
    IUCrJ. 2019; 6: 34-45. https://doi.org/10.1107/S2052252518014641
    DORA PSI
  • Galuskin EV, Krüger B, Galuskina IO, Krüger H, Vapnik Y, Pauluhn A, et al.
    Levantite, KCa3(Al2Si3)O11(PO4), a new latiumite group mineral from pyrometamorphic rock of the Hatrurim Basin, Negev Desert, Israel
    Mineralogical Magazine. 2019; 83(5): 713-721. https://doi.org/10.1180/mgm.2019.37
    DORA PSI
  • Jaeger K, Bruenle S, Weinert T, Guba W, Muehle J, Miyazaki T, et al.
    Structural basis for allosteric ligand recognition in the human CC chemokine receptor 7
    Cell. 2019; 178(5): 1222-1230. https://doi.org/10.1016/j.cell.2019.07.028
    DORA PSI
  • Jensen SC, Sullivan B, Hartzler DA, Aguilar JM, Awel S, Bajt S, et al.
    X-ray emission spectroscopy at X-ray free electron lasers: limits to observation of the classical spectroscopic response for electronic structure analysis
    Journal of Physical Chemistry Letters. 2019; 10(3): 441-446. https://doi.org/10.1021/acs.jpclett.8b03595
    DORA PSI
  • Kahlenberg V, Galuskina I, Krüger B, Pauluhn A, Galuskin E
    Structural investigations on bredigite from the Hatrurim Complex
    Mineralogy and Petrology. 2019; 113(2): 261-272. https://doi.org/10.1007/s00710-018-0646-z
    DORA PSI
  • Kahlenberg V, Albrecht R, Schmidmair D, Krüger H, Krüger B, Tribus M, et al.
    Structural studies on Ca3Al4MgO10 (C3A2M) - a ternary phase in the system CaO-Al2O3-MgO
    Journal of the American Ceramic Society. 2019; 102(4): 2084-2093. https://doi.org/10.1111/jace.16001
    DORA PSI
  • Leonarski F, D’Ascenzo L, Auffinger P
    Nucleobase carbonyl groups are poor Mg2+ inner-sphere binders but excellent monovalent ion binders - a critical PDB survey
    RNA. 2019; 25(11): 173-192. https://doi.org/10.1261/rna.068437.118
    DORA PSI
  • Li H, Huang C-Y, Govorunova EG, Schafer CT, Sineshchekov OA, Wang M, et al.
    Crystal structure of a natural light-gated anion channelrhodopsin
    eLife. 2019; 8: e41741 (21 pp.). https://doi.org/10.7554/eLife.41741
    DORA PSI
  • Liu X, An T, Li D, Fan Z, Xiang P, Li C, et al.
    Structure of the heterophilic interaction between the nectin-like 4 and nectin-like 1 molecules
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2019; 116(6): 2068-2077. https://doi.org/10.1073/pnas.1810969116
    DORA PSI
  • Makita M, Vartiainen I, Mohacsi I, Caleman C, Diaz A, Jönsson HO, et al.
    Femtosecond phase-transition in hard x-ray excited bismuth
    Scientific Reports. 2019; 9(1): 602 (7 pp.). https://doi.org/10.1038/s41598-018-36216-3
    DORA PSI
  • Martiel I, Müller-Werkmeister HM, Cohen AE
    Strategies for sample delivery for femtosecond crystallography
    Acta Crystallographica Section D: Structural Biology. 2019; 75(2): 160-177. https://doi.org/10.1107/S2059798318017953
    DORA PSI
  • Meyer M, Walbott H, Oliéric V, Kondo J, Costa M, Masquida B
    Conformational adaptation of UNCG loops upon crowding
    RNA. 2019; 25(11): 1522-1531. https://doi.org/10.1261/rna.072694.119
    DORA PSI
  • Nass K
    Radiation damage in protein crystallography at X-ray free-electron lasers
    Acta Crystallographica Section D: Structural Biology. 2019; 75(2): 211-218. https://doi.org/10.1107/S2059798319000317
    DORA PSI
  • Tomizaki T, Shinoda A, Tsujino S
    Single crystal time-lapse measurement using ultrasonic acoustic levitation
    In: Gwo S, Huang D-J, Wei D-H, eds. Proceedings of the 13th international conference on synchrotron radiation instrumentation – SRI2018. Vol. 2054. AIP conference proceedings. Melville, New York: AIP Publishing; 2019:060072 (4 pp.). https://doi.org/10.1063/1.5084703
    DORA PSI
  • Tsujino S, Shinoda A, Tomizaki T
    On-demand droplet loading of ultrasonic acoustic levitator and its application for protein crystallography experiments
    Applied Physics Letters. 2019; 114(21): 213702 (5 pp.). https://doi.org/10.1063/1.5095574
    DORA PSI
  • Tsujino S, Sato Y, Takeda Y, Tomizaki T
    Oscillation resonances and anisotropic damping of the motion of acoustically levitated droplets in single-axis acoustic levitators
    Applied Physics Letters. 2019; 115: 053702 (5 pp.). https://doi.org/10.1063/1.5112109
    DORA PSI
  • Ung KL, Alsarraf HMAB, Olieric V, Kremer L, Blaise M
    Crystal structure of the aminoglycosides N‐acetyltransferase Eis2 from Mycobacterium abscessus
    FEBS Journal. 2019; 286(21): 4342-4355. https://doi.org/10.1111/febs.14975
    DORA PSI
  • Wang W, Yu L-J, Xu C, Tomizaki T, Zhao S, Umena Y, et al.
    Structural basis for blue-green light harvesting and energy dissipation in diatoms
    Science. 2019; 363(6427): eaav0365 (8 pp.). https://doi.org/10.1126/science.aav0365
    DORA PSI
  • Wang N, Bosc C, Ryul Choi S, Boulan B, Peris L, Olieric N, et al.
    Structural basis of tubulin detyrosination by the vasohibin–SVBP enzyme complex
    Nature Structural and Molecular Biology. 2019; 26(7): 571-582. https://doi.org/10.1038/s41594-019-0241-y
    DORA PSI
  • Weinert T, Skopintsev P, James D, Dworkowski F, Panepucci E, Kekilli D, et al.
    Proton uptake mechanism in bacteriorhodopsin captured by serial synchrotron crystallography
    Science. 2019; 365(6448): 61-65. https://doi.org/10.1126/science.aaw8634
    DORA PSI
  • de Wijn R, Hennig O, Roche J, Engilberge S, Rollet K, Fernandez-Millan P, et al.
    A simple and versatile microfluidic device for efficient biomacromolecule crystallization and structural analysis by serial crystallography
    IUCrJ. 2019; 6(3): 454-464. https://doi.org/10.1107/S2052252519003622
    DORA PSI
  • Aher A, Kok M, Sharma A, Rai A, Olieric N, Rodriguez-Garcia R, et al.
    CLASP suppresses microtubule catastrophes through a single TOG domain
    Developmental Cell. 2018; 46(1): 40-58.e8. https://doi.org/10.1016/j.devcel.2018.05.032
    DORA PSI
  • El Ghachi M, Howe N, Huang C-Y, Olieric V, Warshamanage R, Touzé T, et al.
    Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis
    Nature Communications. 2018; 9(1): 1078 (13 pp.). https://doi.org/10.1038/s41467-018-03477-5
    DORA PSI
  • Galuskin EV, Krüger B, Galuskina IO, Krüger H, Vapnik Y, Wojdyla JA, et al.
    New mineral with modular structure derived from hatruritefrom the pyrometamorphic rocks of the hatrurim complex: ariegilatite, BaCa12(SiO4)4(PO4)2F2O, from Negev Desert, Israel
    Minerals. 2018; 8(3): 109 (14 pp.). https://doi.org/10.3390/min8030109
    DORA PSI
  • Galuskin EV, Krüger B, Galuskina IO, Krüger H, Vapnik Y, Pauluhn A, et al.
    Stracherite, BaCa6(SiO4)2[(PO4)(CO3)]F, the first CO3-bearing intercalated hexagonal antiperovskite from Negev Desert, Israel
    American Mineralogist. 2018; 103(10): 1699-1706. https://doi.org/10.2138/am-2018-6493
    DORA PSI
  • Gao X, Mu Z, Yu X, Qin B, Wojdyla J, Wang M, et al.
    Structural insight into conformational changes induced by ATP binding in a type III secretion-associated ATPase from Shigella flexneri
    Frontiers in Microbiology. 2018; 9: 1468 (15 pp.). https://doi.org/10.3389/fmicb.2018.01468
    DORA PSI
  • Horrell S, Kekilli D, Sen K, Owen RL, Dworkowski FSN, Antonyuk SV, et al.
    Enzyme catalysis captured using multiple structures from one crystal at varying temperatures
    IUCrJ. 2018; 5(3): 283-292. https://doi.org/10.1107/S205225251800386X
    DORA PSI
  • Huang C-Y, Olieric V, Howe N, Warshamanage R, Weinert T, Panepucci E, et al.
    In situ serial crystallography for rapid de novo membrane protein structure determination.
    Communications Biology. 2018; 1: 124 (8 pp.). https://doi.org/10.1038/S42003-018-0123-6
    DORA PSI
  • Juroszek R, Krüger H, Galuskina I, Krüger B, Jeżak L, Ternes B, et al.
    Sharyginite, Ca3TiFe2O8a new mineral from the Bellerberg volcano, Germany
    Minerals. 2018; 8(7): 308. https://doi.org/10.3390/min8070308
    DORA PSI
  • Krüger B, Krüger H, Galuskin EV, Galuskina IO, Vapnik Y, Olieric V, et al.
    Aravaite, Ba2Ca18(SiO4)6(PO4)3(CO3)F3O: modular structure and disorder of a new mineral with single and triple antiperovskite layers
    Acta Crystallographica Section B: Structural Science, Crystal Engineering and Materials. 2018; 74(6): 492-501. https://doi.org/10.1107/S2052520618012271
    DORA PSI
  • Küssau T, Flipo M, Van Wyk N, Viljoen A, Olieric V, Kremer L, et al.
    Structural rearrangements occurring upon cofactor binding in the Mycobacterium smegmatis β-ketoacyl-acyl carrier protein reductase MabA
    Acta Crystallographica Section D: Structural Biology. 2018; D74(Part 5): 383-393. https://doi.org/10.1107/S2059798318002917
    DORA PSI
  • Lebugle M, Dworkowski F, Pauluhn A, Guzenko VA, Romano L, Meier N, et al.
    High-intensity x-ray microbeam for macromolecular crystallography using silicon kinoform diffractive lenses
    Applied Optics. 2018; 57(30): 9032-9039. https://doi.org/10.1364/AO.57.009032
    DORA PSI
  • Leonarski F, Redford S, Mozzanica A, Lopez-Cuenca C, Panepucci E, Nass K, et al.
    Fast and accurate data collection for macromolecular crystallography using the JUNGFRAU detector
    Nature Methods. 2018; 15(10): 799-804. https://doi.org/10.1038/s41592-018-0143-7
    DORA PSI
  • Martiel I, Olieric V, Caffrey M, Wang M
    Practical approaches for in situ X-ray crystallography: from high-throughput screening to serial data collection
    In: Beis K, Evans G, eds. Protein crystallography: challenges and practical solutions. Chemical biology. Cambridge: Royal Society of Chemistry; 2018:1-27. https://doi.org/10.1039/9781788010504-00001
    DORA PSI
  • Mozzanica A, Andrä M, Barten R, Bergamaschi A, Chiriotti S, Brückner M, et al.
    The JUNGFRAU detector for applications at synchrotron light sources and XFELs
    Synchrotron Radiation News. 2018; 31(6): 16-20. https://doi.org/10.1080/08940886.2018.1528429
    DORA PSI
  • Nogly P, Weinert T, James D, Carbajo S, Ozerov D, Furrer A, et al.
    Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser
    Science. 2018; 361(6398): eaat0094 (7 pp.). https://doi.org/10.1126/science.aat0094
    DORA PSI
  • Nuti E, Cuffaro D, Bernardini E, Camodeca C, Panelli L, Chaves S, et al.
    Development of thioaryl-based matrix metalloproteinase-12 inhibitors with alternative zinc-binding groups: synthesis, potentiometric, NMR, and crystallographic studies
    Journal of Medicinal Chemistry. 2018; 61(10): 4421-4435. https://doi.org/10.1021/acs.jmedchem.8b00096
    DORA PSI
  • Opara NL, Mohacsi I, Makita M, Castano-Diez D, Diaz A, Juranić P, et al.
    Demonstration of femtosecond X-ray pump X-ray probe diffraction on protein crystals
    Structural Dynamics. 2018; 5(5): 054303 (15 pp.). https://doi.org/10.1063/1.5050618
    DORA PSI
  • Pande K, Donatelli JJ, Malmerberg E, Foucar L, Poon BK, Sutter M, et al.
    Free-electron laser data for multiple-particle fluctuation scattering analysis
    Scientific Data. 2018; 5: 180201. https://doi.org/10.1038/sdata.2018.201
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  • Feng S, Chen Y, Kamada K, Wang H, Tang K, Wang M, et al.
    YoeB-ribosome structure: a canonical RNase that requires the ribosome for its specific activity
    Nucleic Acids Research. 2013; 41(20): 9549-9556. https://doi.org/10.1093/nar/gkt742
    DORA PSI
  • Gao Y, Ran T, Marsh M, Zhu W, Wang M, Mao X, et al.
    Crystal structures of Cg1458 reveal a catalytic lid domain and a common catalytic mechanism for the FAH family
    Biochemical Journal. 2013; 449(1): 51-60. https://doi.org/10.1042/BJ20120913
    DORA PSI
  • Gao X, Zou T, Mu Z, Qin B, Yang J, Waltersperger S, et al.
    Structural insights into VirB-DNA complexes reveal mechanism of transcriptional activation of virulence genes
    Nucleic Acids Research. 2013; 41(22): 10529-10541. https://doi.org/10.1093/nar/gkt748
    DORA PSI
  • Merlino A, Fuchs MR, Pica A, Balsamo A, Dworkowski FSN, Pompidor G, et al.
    Selective X-ray-induced NO photodissociation in haemoglobin crystals: evidence from a Raman-assisted crystallographic study
    Acta Crystallographica Section D: Structural Biology. 2013; 69(1): 137-140. https://doi.org/10.1107/S0907444912042229
    DORA PSI
  • Pinker F, Brun M, Morin P, Deman A-L, Chateaux J-F, Oliéric V, et al.
    ChipX: a novel microfluidic chip for counter-diffusion crystallization of biomolecules and in situ crystal analysis at room temperature
    Crystal Growth and Design. 2013; 13(8): 3333-3340. https://doi.org/10.1021/CG301757G
    DORA PSI
  • Pompidor G, Dworkowski FSN, Thominet V, Schulze-Briese C, Fuchs MR
    A new on-axis micro-spectrophotometer for combining Raman, fluorescence and UV/Vis absorption spectroscopy with macromolecular crystallography at the Swiss Light Source
    Journal of Synchrotron Radiation. 2013; 20(5): 765-776. https://doi.org/10.1107/S0909049513016063
    DORA PSI
  • Schacherl M, Waltersperger S, Baumann U
    Structural characterization of the ribonuclease H-like type ASKHA superfamily kinase MK0840 from Methanopyrus kandleri
    Acta Crystallographica Section D: Structural Biology. 2013; 69(12): 2440-2450. https://doi.org/10.1107/S0907444913022683
    DORA PSI
  • Truan D, Vasil A, Stonehouse M, Vasil ML, Pohl E
    High-level over-expression, purification, and crystallization of a novel phospholipase C/sphingomyelinase from Pseudomonas aeruginosa
    Protein Expression and Purification. 2013; 90(1): 40-46. https://doi.org/10.1016/j.pep.2012.11.005
    DORA PSI
  • Wu M, Tong S, Waltersperger S, Diederichs K, Wang M, Zheng L
    Crystal structure of Ca2+/H+ antiporter protein YfkE reveals the mechanisms of Ca2+ efflux and its pH regulation
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2013; 110(28): 11367-11372. https://doi.org/10.1073/pnas.1302515110
    DORA PSI
  • Xia L, Rajendran C, Ruppert M, Panjikar S, Wang M, Stoeckigt J
    High speed X-ray analysis of plant enzymes at room temperature
    Phytochemistry. 2013; 91: 88-92. https://doi.org/10.1016/j.phytochem.2012.05.009
    DORA PSI
  • Bosak A, Krisch M, Chernyshov D, Winkler B, Milman V, Refson K, et al.
    New insights into the lattice dynamics of α-quartz
    Zeitschrift für Kristallographie. 2012; 227(2): 84-91. https://doi.org/10.1524/zkri.2012.1432
    DORA PSI
  • Chong H, Yao X, Qiu Z, Qin B, Han R, Waltersperger S, et al.
    Discovery of critical residues for viral entry and inhibition through structural insight of HIV-1 fusion inhibitor CP621-652
    Journal of Biological Chemistry. 2012; 287(24): 20281-20289. https://doi.org/10.1074/jbc.M112.354126
    DORA PSI
  • Chong H, Yao X, Sun J, Qiu Z, Zhang M, Waltersperger S, et al.
    The M-T hook structure is critical for design of HIV-1 fusion inhibitors
    Journal of Biological Chemistry. 2012; 287(41): 34558-34568. https://doi.org/10.1074/jbc.M112.390393
    DORA PSI
  • Cousido-Siah A, Ayoub D, Berberián G, Bollo M, Van Dorsselaer A, Debaene F, et al.
    Structural and functional studies of ReP1-NCXSQ, a protein regulating the squid nerve Na+/Ca2+ exchanger
    Acta Crystallographica Section D: Structural Biology. 2012; 68(9): 1098-1107. https://doi.org/10.1107/S090744491202094X
    DORA PSI
  • Graef C, Schacherl M, Waltersperger S, Baumann U
    Crystal structures of archaemetzincin reveal a moldable substrate-binding site
    PLoS One. 2012; 7(8): e43863 (8 pp.). https://doi.org/10.1371/journal.pone.0043863
    DORA PSI
  • He C, Fuchs MR, Ogata H, Knipp M
    Guanidine-ferroheme coordination in the mutant protein nitrophorin 4(L130R)
    Angewandte Chemie International Edition. 2012; 51(18): 4470-4473. https://doi.org/10.1002/anie.201108691
    DORA PSI
  • Lerch P, Quaroni L, Wambach J, Schneider J, Armstrong DB, Rossetti D, et al.
    IR beamline at the Swiss Light Source
    In: Vol. 359. Journal of physics: conference series. Institute of Physics Publishing; 2012:12003. https://doi.org/10.1088/1742-6596/359/1/012003
    DORA PSI
  • Mueller U, Darowski N, Fuchs MR, Förster R, Hellmig M, Paithankar KS, et al.
    Facilities for macromolecular crystallography at the Helmholtz-Zentrum Berlin
    Journal of Synchrotron Radiation. 2012; 19(3): 442-449. https://doi.org/10.1107/S0909049512006395
    DORA PSI
  • Mueller M, Wang M, Schulze-Briese C
    Optimal fine φ-slicing for single-photon-counting pixel detectors
    Acta Crystallographica Section D: Structural Biology. 2012; 68(1): 42-56. https://doi.org/10.1107/S0907444911049833
    DORA PSI
  • Pham SQ, Pompidor G, Liu J, Li X-D, Li Z
    Evolving P450pyr hydroxylase for highly enantioselective hydroxylation at non-activated carbon atom
    Chemical Communications. 2012; 48(38): 4618-4620. https://doi.org/10.1039/c2cc30779k
    DORA PSI
  • Pradervand C, Bednarzik M, Schmitt B, Mozzanica A, Schulze-Briese C
    A CVD diamond based X-ray beam profile sensor combined with the Gotthard charge integrating readout
    Presented at: 11th International conference on synchrotron radiation instrumentation (SRI2012); July 9-13, 2012; Lyon, France.
    DORA PSI
  • Sun L, Chen Y, Rajendran C, Mueller U, Panjikar S, Wang M, et al.
    Crystal structure of perakine reductase, founding member of a novel Aldo-Keto Reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding
    Journal of Biological Chemistry. 2012; 287(14): 11213-11221. https://doi.org/10.1074/jbc.M111.335521
    DORA PSI
  • Wang N, Wang M, Gao Y, Ran T, Lan Y, Wang J, et al.
    Crystallization and preliminary X-ray crystallographic analysis of a blue-light-absorbing proteorhodopsin
    Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 2012; 68(3): 281-283. https://doi.org/10.1107/S1744309111043612
    DORA PSI
  • Wu F, Zhu H, Sun L, Rajendran C, Wang M, Ren X, et al.
    Scaffold tailoring by a newly detected pictet-spenglerase activity of strictosidine synthase: From the common tryptoline skeleton to the rare piperazino-indole framework
    Journal of the American Chemical Society. 2012; 134(3): 1498-1500. https://doi.org/10.1021/ja211524d
    DORA PSI
  • Xia L, Ruppert M, Wang M, Panjikar S, Lin H, Rajendran C, et al.
    Structures of alkaloid biosynthetic glucosidases decode substrate specificity
    ACS Chemical Biology. 2012; 7(1): 226-234. https://doi.org/10.1021/cb200267w
    DORA PSI
  • Yao X, Chong H, Zhang C, Waltersperger S, Wang M, Cui S, et al.
    Broad antiviral activity and crystal structure of HIV-1 fusion inhibitor sifuvirtide
    Journal of Biological Chemistry. 2012; 287(9): 6788-6796. https://doi.org/10.1074/jbc.M111.317883
    DORA PSI
  • Yao X, Chong H, Zhang C, Qiu Z, Qin B, Han R, et al.
    Structural basis of potent and broad HIV-1 fusion inhibitor CP32M
    Journal of Biological Chemistry. 2012; 287(32): 26618-26629. https://doi.org/10.1074/jbc.M112.381079
    DORA PSI
  • Zarrine-Afsar A, Barends TRM, Müller C, Fuchs MR, Lomb L, Schlichting I, et al.
    Crystallography on a chip
    Acta Crystallographica Section D: Structural Biology. 2012; 68(3): 321-323. https://doi.org/10.1107/S0907444911055296
    DORA PSI
  • Zou T, Yao X, Qin B, Zhang M, Cai L, Shang W, et al.
    Crystal structure of Pseudomonas aeruginosa Tsi2 reveals a stably folded superhelical antitoxin
    Journal of Molecular Biology. 2012; 417(4): 351-361. https://doi.org/10.1016/j.jmb.2012.01.040
    DORA PSI
  • Bingel-Erlenmeyer R, Olieric V, Grimshaw JPA, Gabadinho J, Wang X, Ebner SG, et al.
    SLS crystallization platform at beamline X06DA-A fully automated pipeline enabling in situ X-ray diffraction screening
    Crystal Growth and Design. 2011; 11(4): 916-923. https://doi.org/10.1021/cg101375j
    DORA PSI
  • Blaise M, Fréchin M, Oliéric V, Charron C, Sauter C, Lorber B, et al.
    Crystal structure of the archaeal asparagine synthetase: Interrelation with aspartyl-tRNA and asparaginyl-tRNA synthetases
    Journal of Molecular Biology. 2011; 412(3): 437-452. https://doi.org/10.1016/j.jmb.2011.07.050
    DORA PSI
  • Carroll L, Friedli P, Lerch P, Schneider J, Treyer D, Hunziker S, et al.
    Ultra-broadband infrared pump-probe spectroscopy using synchrotron radiation and a tuneable pump
    Review of Scientific Instruments. 2011; 82(6): 63101 (9 pp.). https://doi.org/10.1063/1.3592332
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  • Cui S, Wang J, Fan T, Qin B, Guo L, Lei X, et al.
    Crystal structure of human enterovirus 71 3C protease
    Journal of Molecular Biology. 2011; 408(3): 449-461. https://doi.org/10.1016/j.jmb.2011.03.007
    DORA PSI
  • Kitagawa D, Vakonakis I, Olieric N, Hilbert M, Keller D, Olieric V, et al.
    Structural basis of the 9-fold symmetry of centrioles
    Cell. 2011; 144(3): 364 (12 pp.)-375. https://doi.org/10.1016/j.cell.2011.01.008
    DORA PSI
  • Ostendorp T, Diez J, Heizmann CW, Fritz G
    The crystal structures of human S100B in the zinc- and calcium-loaded state at three pH values reveal zinc ligand swapping
    Biochimica et Biophysica Acta: Molecular Cell Research. 2011; 1813(5): 1083-1091. https://doi.org/10.1016/j.bbamcr.2010.10.006
    DORA PSI
  • Pauluhn A, Pradervand C, Rossetti D, Salathe M, Schulze-Briese C
    Automatic loop centring with a high-precision goniometer head at the SLS macromolecular crystallography beamlines
    Journal of Synchrotron Radiation. 2011; 18(4): 595-600. https://doi.org/10.1107/S0909049511011848
    DORA PSI
  • Rajendran C, Gerhardt ECM, Bjelic S, Gasperina A, Scarduelli M, Pedrosa FO, et al.
    Crystal structure of the GlnZ-DraG complex reveals a different form of P II-target interaction
    Proceedings of the National Academy of Sciences of the United States of America PNAS. 2011; 108(47): 18972-18976. https://doi.org/10.1073/pnas.1108038108
    DORA PSI
  • Rajendran C, Dworkowski FSN, Wang M, Schulze-Briese C
    Radiation damage in room-temperature data acquisition with the PILATUS 6M pixel detector
    Journal of Synchrotron Radiation. 2011; 18(3): 318-328. https://doi.org/10.1107/S090904951100968X
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  • Regis Faro A, Carpentier P, Jonasson G, Pompidor G, Arcizet D, Demachy I, et al.
    Low-temperature chromophore isomerization reveals the photoswitching mechanism of the fluorescent protein Padron
    Journal of the American Chemical Society. 2011; 133(41): 16362-16365. https://doi.org/10.1021/ja207001y
    DORA PSI
  • Schellenberger P, Demangeat G, Lemaire O, Ritzenthaler C, Bergdoll M, Oliéric V, et al.
    Strategies for the crystallization of viruses: Using phase diagrams and gels to produce 3D crystals of Grapevine fanleaf virus
    Journal of Structural Biology. 2011; 174(2): 344-351. https://doi.org/10.1016/j.jsb.2011.02.007
    DORA PSI

Associated Beamlines

Contact

Head of MX
and Group Leader (i.p.) MX Applications
Dr. Meitian Wang
Telephone:
+41 56 310 4175
E-mail:
meitian.wang@psi.ch

Group Leader MX Instrumentation
Wayne Glettig
Telephone:
+41 56 310 5823
E-mail:
wayne.glettig@psi.ch

Group Leader MX Samples
Dr. May Sharpe née Marsh
Telephone:
+41 56 310 5437
E-mail:
may.sharpe@psi.ch

Group Leader MX Data
Dr. Justyna Aleksandra Wojdyla
Telephone:
+41 56 310 5428
E-mail:
justyna.wojdyla@psi.ch