Publications

2019

  • Nuclear Pore Membrane Proteins Self-Assemble into Nanopores Panatala R, Barbato S, Kozai T, Luo J, Kapinos Larisa E, Lim Roderick YH
    BIOCHEMISTRY 58, 484 (2019).
    DOI: 10.1021/acs.biochem.8b01179

2018

  • Botulinum Neurotoxin Diversity from a Gene-Centered View Benoit R
    Toxins 10, 310 (2018).
    DOI: 10.3390/toxins10080310
  • Cerebral Corpora amylacea are dense membranous labyrinths containing structurally preserved cell organelles Navarro Paula P, Genoud C, Castaño-Díez D, Graff-Meyer A, Lewis Amanda J, de Gier Y, Lauer Matthias E, Britschgi M, Bohrmann B, Frank S, Hench J, Schweighauser G, Rozemuller Annemieke JM, van de Berg Wilma DJ, Stahlberg H, Shahmoradian Sarah H
    Scientific Reports 8, 18046 (2018).
    DOI: 10.1038/s41598-018-36223-4
  • Development of Smart Optical Gels with Highly Magnetically Responsive Bicelles Isabettini S, Stucki S, Massabni S, Baumgartner ME, Reckey PQ, Kohlbrecher J, Ishikawa T, Windhab Erich J, Fischer P, Kuster S
    ACS APPLIED MATERIALS & INTERFACES 10, 8926 (2018).
    DOI: 10.1021/acsami.7b17134
  • Electron crystallography with the EIGER detector Tinti G, Fröjdh E, van Genderen E, Gruene T, Schmitt B, de Winter MDA, Weckhuysen BM, Abrahams J
    IUCRJ 5, 190 (2018).
    DOI: 10.1107/S2052252518000945
  • Frontispiece: Characterization at the Level of Individual Crystals: Single-Crystal MFI Type Zeolite Grains Gruene T, Li T, van Genderen E, Pinar Ana B, van Bokhoven JA
    CHEMISTRY - A EUROPEAN JOURNAL 24, 2384 (2018).
    DOI: 10.1002/chem.201881065

2017

  • Baculovirus-based genome editing in primary cells Mansouri M, Ehsaei Z, Taylor V, Berger P
    PLASMID 90, 5 (2017).
    DOI: 10.1016/j.plasmid.2017.01.003
  • Characterization at the level of individual crystals: single crystal MFI type zeolite grains Gruene T, Li T, van Genderen E, Pinar AB, van Bokhoven JA
    CHEMISTRY - A EUROPEAN JOURNAL 24, 2384 (2017).
    DOI: 10.1002/chem.201704213
  • Comprehensive Analysis of the Role of Arrestin Residues in Receptor Binding Haider Raphael S, Rizk A, Schertler G, Ostermaier M
    Springer International Publishing -, 83 (2017).
    DOI: 10.1007/978-3-319-57553-7_7
  • Crystal structure of the BoNT/A2 receptor-binding domain in complex with the luminal domain of its neuronal receptor SV2C Benoit RM, Schaerer MA, Wieser MM, Li X, Frey D, Kammerer RA
    Scientific Reports 7, 43588 (2017).
    DOI: 10.1038/srep43588
  • Mastering the magnetic susceptibility of magnetically responsive bicelles with 3?-amino-5-cholestene and complexed lanthanide ions Isabettini S, Liebi M, Kohlbrecher J, Ishikawa T, Fischer P, Windhab Erich J, Walde P, Kuster S
    PHYSICAL CHEMISTRY CHEMICAL PHYSICS 19, 10820 (2017).
    DOI: 10.1039/C7CP01025G
  • Methods for Generating Highly Magnetically Responsive Lanthanide-Chelating Phospholipid Polymolecular Assemblies Isabettini S, Baumgartner Mirjam E, Reckey Pernille Q, Kohlbrecher J, Ishikawa T, Fischer P, Windhab Erich J, Kuster S
    LANGMUIR 33, 6363 (2017).
    DOI: 10.1021/acs.langmuir.7b00725
  • Molecular engineering of lanthanide ion chelating phospholipids generating assemblies with a switched magnetic susceptibility Isabettini S, Massabni S, Hodzic A, Durovic D, Kohlbrecher J, Ishikawa T, Fischer P, Windhab Erich J, Walde P, Kuster S
    Phys. Chem. Chem. Phys. 19, 20991 (2017).
    DOI: 10.1039/C7CP03994H
  • OMNY PIN - A versatile sample holder for tomographic measurements at room and cryogenic temperatures Holler M, Raabe J, Wepf R, Shahmoradian SH, Diaz A, Sarafimov B, Lachat T, Walther H, Vitins M
    REVIEW OF SCIENTIFIC INSTRUMENTS 88, 113701 (2017).
    DOI: 10.1063/1.4996092
  • Protein structure determination by electron diffraction using a single three-dimensional nanocrystal Clabbers MTB, van Genderen E, Wan W, Wiegers EL, Gruene T, Abrahams JP
    Acta Crystallographica Section D Structural Biology 73, 738 (2017).
    DOI: 10.1107/S2059798317010348
  • Three-Dimensional Imaging of Biological Tissue by Cryo X-Ray Ptychography Shahmoradian SH, Tsai EHR, Diaz A, Guizar-Sicairos M, Raabe J, Spycher L, Britschgi M, Ruf A, Stahlberg H, Holler M
    Scientific Reports 7, 6291 (2017).
    DOI: 10.1038/s41598-017-05587-4

2016

  • A simple and fast approach for missing-wedge invariant classification of subtomograms extracted from filamentous structures Obbineni J, Yamamoto R, Ishikawa T
    JOURNAL OF STRUCTURAL BIOLOGY , (2016).
    DOI: 10.1016/j.jsb.2016.08.003
  • Ab initio structure determination of nanocrystals of organic pharmaceutical compounds by electron diffraction at room temperature using a Timepix quantum area direct electron detector van Genderen E, Clabbers MTB, Das PP, Stewart A, Nederlof I, Barentsen KC, Portillo Q, Pannu NS, Nicolopoulos S, Gruene T, Abrahams JP
    Acta Crystallographica Section A Foundations and Advances 72, 236 (2016).
    DOI: 10.1107/S2053273315022500
  • Addendum to Three-dimensional mass density mapping of cellular ultrastructure by ptychographic X-ray nanotomography [J. Struct. Biol. 192 (2015) 461-469] Diaz A, Malkova B, Holler M, Guizar-Sicairos M, Lima E, Panneels V, Pigino G, Bittermann A, Wettstein L, Tomizaki T, Bunk O, Schertler G, Ishikawa T, Wepf R, Menzel A
    JOURNAL OF STRUCTURAL BIOLOGY 193, 83 (2016).
    DOI: 10.1016/j.jsb.2015.12.003
  • Biochemie und Molekularbiologie Christen P, Jaussi R, Benoit R
    Springer Verlag Berlin Heidelberg , (2016).
    DOI: 10.1007/978-3-662-46430-4_1
  • Characterization of Mn(II) ion binding to the amyloid-? peptide in Alzheimer?s disease Wallin C, Kulkarni Yashraj S, Abelein A, Jarvet J, Liao Q, Strodel B, Olsson L, Luo J, Abrahams J, Sholts Sabrina B, Roos Per M, Kamerlin Shina CL, Gräslund A, Wärmländer Sebastian KTS
    JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY , (2016).
    DOI: 10.1016/j.jtemb.2016.03.009
  • Control of the structural landscape and neuronal proteotoxicity of mutant Huntingtin by domains flanking the polyQ tract Shen K, Calamini B, Fauerbach J, Ma B, Shahmoradian S, Serrano Lachapel I, Chiu W, Lo D, Frydman J
    ELIFE 5, (2016).
    DOI: 10.7554/eLife.18065
  • Cross-interactions between the Alzheimer Disease Amyloid-? Peptide and Other Amyloid Proteins: A Further Aspect of the Amyloid Cascade Hypothesis Luo J, Wärmländer Sebastian KTS, Gräslund A, Abrahams J
    JOURNAL OF BIOLOGICAL CHEMISTRY 291, 16485 (2016).
    DOI: 10.1074/jbc.R116.714576
  • Functional map of arrestin binding to phosphorylated opsin, with and without agonist Peterhans C, Lally Ciara CM, Ostermaier Martin K, Sommer Martha E, Standfuss J
    Scientific Reports 6, 28686 (2016).
    DOI: 10.1038/srep28686
  • Functional map of arrestin binding to phosphorylated opsin, with and without agonist (vol 6, 28686, 2016) Peterhans Christian, Lally Ciara C M, Ostermaier Martin K, Sommer Martha E, Standfuss Jorg
    Scientific Reports 6, 30224 (2016).
    DOI: 10.1038/srep30224
  • Highly efficient baculovirus-mediated multigene delivery in primary cells Mansouri M, Bellon-Echeverria I, Rizk A, Ehsaei Z, Cianciolo Cosentino C, Silva Catarina S, Xie Y, Boyce Frederick M, Davis MWayne, Neuhauss Stephan CF, Taylor V, Ballmer-Hofer K, Berger I, Berger P
    NATURE COMMUNICATIONS 7, 11529 (2016).
    DOI: 10.1038/ncomms11529
  • Lattice filter for processing image data of three-dimensional protein nanocrystals van Genderen E, Li YW, Nederlof I, Abrahams JP
    ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY 72, 34 (2016).
    DOI: 10.1107/S205979831502149X
  • Modern X-ray analysis on single crystals - a practical guide Gruene T
    Crystallography Reviews 22, 287 (2016).
    DOI: 10.1080/0889311X.2016.1237508
  • Reciprocal Molecular Interactions between the A? Peptide Linked to Alzheimer?s Disease and Insulin Linked to Diabetes Mellitus Type II Luo J, Wärmländer Sebastian KTS, Gräslund A, Abrahams J
    ACS Chemical Neuroscience 7, 269 (2016).
    DOI: 10.1021/acschemneuro.5b00325
  • Seamless Insert-Plasmid Assembly at High Efficiency and Low Cost Benoit RM, Ostermeier C, Geiser M, Li JSZ, Widmer H, Auer M
    PLOS ONE 11, e0153158 (2016).
    DOI: 10.1371/journal.pone.0153158
  • Structural basis for misregulation of kinesin KIF21A autoinhibition by CFEOM1 disease mutations Bianchi S, van Riel Wilhelmina E, Kraatz Sebastian HW, Olieric N, Frey D, Katrukha Eugene A, Jaussi R, Missimer J, Grigoriev I, Olieric V, Benoit Roger M, Steinmetz Michel O, Akhmanova A, Kammerer Richard A
    Scientific Reports 6, 30668 (2016).
    DOI: 10.1038/srep30668
  • TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington?s disease Zhao X, Chen X, Han E, Hu Y, Paik P, Ding Z, Overman J, Lau Alice L, Shahmoradian SH, Chiu W, Thompson Leslie M, Wu C, Mobley William C
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 113, E5655 (2016).
    DOI: 10.1073/pnas.1603020113
  • Tailoring Bicelle Morphology and Thermal Stability with Lanthanide-Chelating Cholesterol Conjugates Isabettini S, Liebi M, Kohlbrecher J, Ishikawa T, Windhab Erich J, Fischer P, Walde P, Kuster S
    LANGMUIR 32 (35), 9005 (2016).
    DOI: 10.1021/acs.langmuir.6b01968

2015

  • A posteriori correction of camera characteristics from large image data sets Afanasyev P, Ravelli Raimond BG, Matadeen R, De Carlo S, van Duinen G, Alewijnse B, Peters Peter J, Abrahams J, Portugal Rodrigo V, Schatz M, van Heel M
    Scientific Reports 5, 10317 (2015).
    DOI: 10.1038/srep10317
  • Bilayer Properties of 1,3-Diamidophospholipids Weinberger A, Tanasescu R, Stefaniu C, Fedotenko lllya A, Favarger F, Ishikawa T, Brezesinski G, Marques Carlos M, Zumbuehl A
    LANGMUIR 31, 1879 (2015).
    DOI: 10.1021/la5041745
  • Cryo-electron tomography of motile cilia and flagella Ishikawa T
    Cilia 4, 3 (2015).
    DOI: 10.1186/s13630-014-0012-7
  • Electron crystallography of 3D nano-crystals Clabbers Max TB, van Genderen E, Nederlof I, Li Y, Abrahams J
    Acta Crystallographica Section A Foundations and Advances 71, s405 (2015).
    DOI: 10.1107/S2053273315093985
  • Electron diffraction and imaging of 3D nanocrystals of pharmaceuticals, peptides and proteins Abrahams J, van Genderen E, Nederlof I, Clabbers M, Li Y
    Acta Crystallographica Section A Foundations and Advances 71, s103 (2015).
    DOI: 10.1107/S2053273315098496
  • RAFT synthesis of poly(vinylpyrrolidone) amine and preparation of a water-soluble C 60 -PVP conjugate Aroua S, Tiu Elisha Gabrielle V, Ayer M, Ishikawa T, Yamakoshi Y
    Polym. Chem. 6, 2616 (2015).
    DOI: 10.1039/C4PY01333F
  • Structure of the BoNT/A1 - receptor complex Benoit Roger M, Frey D, Wieser Mara M, Thieltges Katherine M, Jaussi R, Capitani G, Kammerer Richard A
    TOXICON 107, 25 (2015).
    DOI: 10.1016/j.toxicon.2015.08.002
  • Subcellular object quantification with Squassh3C and SquasshAnalyst Rizk A, Mansouri M, Ballmer-Hofer K, Berger P
    BIOTECHNIQUES 59, (2015).
    DOI: 10.2144/000114352
  • Synthesis of Single Crystal Nanoreactor Materials with Multiple Catalytic Functions by Incipient Wetness Impregnation and Ion Exchange Fodor D, Ishikawa T, Krumeich F, van Bokhoven Jeroen A
    ADVANCED MATERIALS 27, 1919 (2015).
    DOI: 10.1002/adma.201404628
  • Three-dimensional mass density mapping of cellular ultrastructure by ptychographic X-ray nanotomography Diaz A, Malkova B, Holler M, Guizar-Sicairos M, Lima E, Panneels V, Pigino G, Bittermann A, Wettstein L, Tomizaki T, Bunk O, Schertler G, Ishikawa T, Wepf R, Menzel A
    JOURNAL OF STRUCTURAL BIOLOGY 192, 461 (2015).
    DOI: 10.1016/j.jsb.2015.10.008
  • alpha- and beta-Tubulin Lattice of the Axonemal Microtubule Doublet and Binding Proteins Revealed by Single Particle Cryo-Electron Microscopy and Tomography Maheshwari A, Obbineni J, Bui K, Shibata K, Toyoshima Yoko Y, Ishikawa T
    STRUCTURE 23, 1584 (2015).
    DOI: 10.1016/j.str.2015.06.017

2014

  • Alzheimer Peptides Aggregate into Transient Nanoglobules That Nucleate Fibrils Luo J, Wärmländer Sebastian KTS, Gräslund A, Abrahams J
    BIOCHEMISTRY 53, 6302 (2014).
    DOI: 10.1021/bi5003579
  • ChemInform Abstract: Cyclic Peptides as Inhibitors of Amyloid Fibrillation Luo J, Abrahams J
    ChemInform 45, no (2014).
    DOI: 10.1002/chin.201422265
  • Cyclic Peptides as Inhibitors of Amyloid Fibrillation Luo J, Abrahams J
    CHEMISTRY - A EUROPEAN JOURNAL 20, 2410 (2014).
    DOI: 10.1002/chem.201304253
  • Endogenous Polyamines Reduce the Toxicity of Soluble A? Peptide Aggregates Associated with Alzheimer?s Disease Luo J, Mohammed I, Wärmländer Sebastian KTS, Hiruma Y, Gräslund A, Abrahams J
    BIOMACROMOLECULES 15, 1985 (2014).
    DOI: 10.1021/bm401874j
  • Functional map of arrestin-1 at single amino acid resolution Ostermaier Martin K, Peterhans Christian, Jaussi Rolf, Deupi Xavier, Standfuss Joerg
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111, 1825-1830 (2014).
    DOI: 10.1073/pnas.1319402111
  • Magnetically Enhanced Bicelles Delivering Switchable Anisotropy in Optical Gels Liebi M, Kuster S, Kohlbrecher J, Ishikawa T, Fischer P, Walde P, Windhab EJ
    ACS APPLIED MATERIALS & INTERFACES 6, 1100-1105 (2014).
    DOI: 10.1021/am4046469
  • Molecular mechanism of phosphorylation-dependent arrestin activation Ostermaier M, Schertler G, Standfuss J
    CURRENT OPINION IN STRUCTURAL BIOLOGY 29, 143 (2014).
    DOI: 10.1016/j.sbi.2014.07.006
  • NRP1 Presented in trans to the Endothelium Arrests VEGFR2 Endocytosis, Preventing Angiogenic Signaling and Tumor Initiation Koch S, van Meeteren Laurens A, Morin E, Testini C, Weström S, Björkelund H, Le Jan S, Adler J, Berger P, Claesson-Welsh L
    DEVELOPMENTAL CELL 28, 633 (2014).
    DOI: 10.1016/j.devcel.2014.02.010
  • Non-chaperone Proteins Can Inhibit Aggregation and Cytotoxicity of Alzheimer Amyloid ? Peptide Luo J, Wärmländer Sebastian KTS, Gräslund A, Abrahams J
    JOURNAL OF BIOLOGICAL CHEMISTRY 289, 27766 (2014).
    DOI: 10.1074/jbc.M114.574947
  • Preparation of Primary Neurons for Visualizing Neurites in a Frozen-hydrated State Using Cryo-Electron Tomography Shahmoradian SH, Galiano Mauricio R, Wu C, Chen S, Rasband Matthew N, Mobley William C, Chiu W
    Journal of Visualized Experiments -, - (2014).
    DOI: 10.3791/50783
  • Protein tagging reveals new insights into signaling in flagella Ishikawa T
    The Journal of Cell Biology 204, 631 (2014).
    DOI: 10.1083/jcb.201401142
  • Segmentation and quantification of subcellular structures in fluorescence microscopy images using Squassh Rizk A, Paul G, Incardona P, Bugarski M, Mansouri M, Niemann A, Ziegler U, Berger P, Sbalzarini I
    NATURE PROTOCOLS 9, 586 (2014).
    DOI: 10.1038/nprot.2014.037
  • Strategies for multigene expression in eukaryotic cells Mansouri M, Berger P
    PLASMID 75, 12 (2014).
    DOI: 10.1016/j.plasmid.2014.07.001
  • Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A Benoit Roger M, Frey Daniel, Hilbert Manuel, Kevenaar Josta T, Wieser Mara M, Stirnimann Christian U, McMillan David, Ceska Tom, Lebon Florence, Jaussi Rolf, Steinmetz Michel O, Schertler Gebhard F X, Hoogenraad Casper C, Capitani Guido, Kammerer Richard A
    NATURE 505, 108-+ (2014).
    DOI: 10.1038/nature12732
  • Structure of dimeric axonemal dynein in cilia suggests an alternative mechanism of force generation Ueno H, Bui K, Ishikawa T, Imai Y, Yamaguchi T, Ishikawa T
    Cytoskeleton 71, 412 (2014).
    DOI: 10.1002/cm.21180
  • The A- peptide forms non-amyloid fibrils in the presence of carbon nanotubes Luo J, Waermlaender Sebastian KTS, Yu C, Muhammad K, Graeslund A, Abrahams JP
    NANOSCALE 6, 6720 (2014).
    DOI: 10.1039/c4nr00291a
  • The hairpin conformation of the amyloid ? peptide is an important structural motif along the aggregation pathway Abelein A, Abrahams J, Danielsson J, Gräslund A, Jarvet J, Luo J, Tiiman A, Wärmländer Sebastian KTS
    JBIC JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 19, 623 (2014).
    DOI: 10.1007/s00775-014-1131-8

2013

  • A Medipix quantum area detector allows rotation electron diffraction data collection from submicrometre three-dimensional protein crystals Nederlof I, van Genderen E, Li Y, Abrahams J
    ACTA CRYSTALLOGRAPHICA SECTION D - BIOLOGICAL CRYSTALLOGRAPHY 69, 1223 (2013).
    DOI: 10.1107/S0907444913009700
  • AAscan, PCRdesign and MutantChecker: A Suite of Programs for Primer Design and Sequence Analysis for High-Throughput Scanning Mutagenesis Sun D, Ostermaier Martin K, Heydenreich Franziska M, Mayer D, Jaussi R, Standfuss J, Veprintsev Dmitry B
    PLOS ONE 8, e78878 (2013).
    DOI: 10.1371/journal.pone.0078878
  • An efficient nanolitre-volume multi-channel device for highly viscous materials used in membrane protein crystallization Luo J, Zwier R, Abrahams J
    JOURNAL OF APPLIED CRYSTALLOGRAPHY 46, 829 (2013).
    DOI: 10.1107/S0021889813006742
  • Anomalous signal from S atoms in protein crystallographic data from an X-ray free-electron laser Barends Thomas R M, Foucar Lutz, Shoeman Robert L, Bari Sadia, Epp Sascha W, Hartmann Robert, Hauser Gunter, Huth Martin, Kieser Christian, Lomb Lukas, Motomura Koji, Nagaya Kiyonobu, Schmidt Carlo, Strecker Rafael, Anielski Denis, Boll Rebecca, Erk Benjamin, Fukuzawa Hironobu, Hartmann Elisabeth, Hatsui Takaki, Holl Peter, Inubushi Yuichi, Ishikawa Tetsuya, Kassemeyer Stephan, Kaiser Christian, Koeck Frank, Kunishima Naoki, Kurka Moritz, Rolles Daniel, Rudek Benedikt, Rudenko Artem, Sato Takahiro, Schroeter Claus-Dieter, Soltau Heike, Strueder Lothar, Tanaka Tomoyuki, Togashi Tadashi, Tono Kensuke, Ullrich Joachim, Yase Satoshi, Wada Shin-ichi, Yao Makoto, Yabashi Makina, Ueda Kiyoshi, Schlichting Ilme
    ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 69, 838-842 (2013).
    DOI: 10.1107/S0907444913002448
  • Biophysical Studies of the Amyloid ?-Peptide: Interactions with Metal Ions and Small Molecules Wärmländer S, Tiiman A, Abelein A, Luo J, Jarvet J, Söderberg Kajsa L, Danielsson J, Gräslund A
    CHEMBIOCHEM 14, 1692 (2013).
    DOI: 10.1002/cbic.201300262
  • Capture of unstable protein complex on the streptavidin-coated single-walled carbon nanotubes Liu Z, Voskamp P, Zhang Y, Chu F, Abrahams J
    JOURNAL OF NANOPARTICLE RESEARCH 15, (2013).
    DOI: 10.1007/s11051-013-1582-9
  • Cellular Polyamines Promote Amyloid-Beta (A?) Peptide Fibrillation and Modulate the Aggregation Pathways Luo J, Yu C, Yu H, Borstnar R, Kamerlin Shina CL, Gräslund A, Abrahams J, Wärmländer Sebastian KTS
    ACS Chemical Neuroscience 4, 454 (2013).
    DOI: 10.1021/cn300170x
  • Cholesterol-Diethylenetriaminepentaacetate Complexed with Thulium Ions Integrated into Bicelles To Increase Their Magnetic Alignability Liebi M, Kuster S, Kohlbrecher J, Ishikawa T, Fischer P, Walde P, Windhab Erich J
    JOURNAL OF PHYSICAL CHEMISTRY B 117, 14743 (2013).
    DOI: 10.1021/jp406599c
  • Constitutively active rhodopsin mutants causing night blindness are effectively phosphorylated by GRKs but differ in arrestin-1 binding Vishnivetskiy SergeyA, Ostermaier Martin K, Singhal A, Panneels V, Homan Kristoff T, Glukhova A, Sligar Stephen G, Tesmer John JG, Schertler Gebhard FX, Standfuss J, Gurevich Vsevolod V
    CELLULAR SIGNALLING 25, 2155 (2013).
    DOI: 10.1016/j.cellsig.2013.07.009
  • Coordination of VEGF receptor trafficking and signaling by coreceptors Nakayama M, Berger P
    EXPERIMENTAL CELL RESEARCH 319, 1340 (2013).
    DOI: 10.1016/j.yexcr.2013.03.008
  • Human lysozyme inhibits the in vitro aggregation of A? peptides, which in vivo are associated with Alzheimer's disease Luo J, Wärmländer Sebastian KTS, Gräslund A, Abrahams J
    CHEMICAL COMMUNICATIONS 49, 6507 (2013).
    DOI: 10.1039/c3cc42325e
  • Imaging protein three-dimensional nanocrystals with cryo-EM Nederlof I, Li Y, van Heel M, Abrahams J
    ACTA CRYSTALLOGRAPHICA SECTION D - BIOLOGICAL CRYSTALLOGRAPHY 69, 852 (2013).
    DOI: 10.1107/S0907444913002734
  • Insights into congenital stationary night blindness based on the structure of G90D rhodopsin Singhal Ankita, Ostermaier Martin K, Vishnivetskiy Sergey A, Panneels Valerie, Homan Kristoff T, Tesmer John J G, Veprintsev Dmitry, Deupi Xavier, Gurevich Vsevolod V, Schertler Gebhard F X, Standfuss Joerg
    EMBO REPORTS 14, 520-526 (2013).
    DOI: 10.1038/embor.2013.44
  • TRiC?s tricks inhibit huntingtin aggregation Shahmoradian S, Galaz-Montoya J, Schmid M, Cong Y, Ma B, Spiess C, Frydman J, Ludtke S, Chiu W
    ELIFE 2, - (2013).
    DOI: 10.7554/eLife.00710
  • Visualizing the localization of transfection complexes during graphene nanoparticle-based transfection Bruggencate F, Laroche F, Zhang Y, Song G, Yin S, Abrahams J, Liu Z
    JOURNAL OF MATERIALS CHEMISTRY B 1, 6353 (2013).
    DOI: 10.1039/C3TB21349H

2012

  • Characterisation of a counting imaging detector for electron detection in the energy range 10?20keV Moldovan G, Sikharulidze I, Matheson J, Derbyshire G, Kirkland AI, Abrahams JP
    Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Dectectors and Associated Equipment 681, 21 (2012).
    DOI: 10.1016/j.nima.2012.03.033
  • Comparative structural analysis of eukaryotic flagella and cilia from Chlamydomonas, Tetrahymena, and sea urchins Pigino G, Maheshwari A, Bui K, Shingyoji C, Kamimura S, Ishikawa T
    JOURNAL OF STRUCTURAL BIOLOGY 178, 199 (2012).
    DOI: 10.1016/j.jsb.2012.02.012
  • Conformation Effects of CpG Methylation on Single-Stranded DNA Oligonucleotides: Analysis of the Opioid Peptide Dynorphin-Coding Sequences Taqi M, Wärmländer Sebastian KTS, Yamskova O, Madani F, Bazov I, Luo J, Zubarev R, Verbeek D, Gräslund A, Bakalkin G
    PLOS ONE 7, e39605 (2012).
    DOI: 10.1371/journal.pone.0039605
  • Examining the promiscuous phosphatase activity of Pseudomonas aeruginosa arylsulfatase: A comparison to analogous phosphatases Luo J, van Loo B, Kamerlin SCL
    PROTEINS: STRUCTURE, FUNCTION, AND BIOINFORMATICS 80, 1211 (2012).
    DOI: 10.1002/prot.24020
  • Functionalized Low-Density Lipoprotein Nanoparticles for in Vivo Enhancement of Atherosclerosis on Magnetic Resonance Images Lowell Andrew N, Qiao H, Liu T, Ishikawa T, Zhang H, Oriana S, Wang M, Ricciotti E, FitzGerald Garret A, Zhou R, Yamakoshi Y
    BIOCONJUGATE CHEMISTRY 23, 2313 (2012).
    DOI: 10.1021/bc300561e
  • Mouse respiratory cilia with the asymmetric axonemal structure on sparsely distributed ciliary cells can generate overall directional flow Ueno H, Ishikawa T, Bui K, Gonda K, Ishikawa T, Yamaguchi T
    Nanomedicine: Nanotechnology, Biology and Medicine 8, 1081 (2012).
    DOI: 10.1016/j.nano.2012.01.004
  • Polarity and asymmetry in the arrangement of dynein and related structures in the Chlamydomonas axoneme Bui K, Yagi T, Yamamoto R, Kamiya R, Ishikawa T
    The Journal of Cell Biology 198, 913 (2012).
    DOI: 10.1083/jcb.201201120
  • Revisiting the Supramolecular Organization of Photosystem II in Chlamydomonas reinhardtii Tokutsu R, Kato N, Bui KH, Ishikawa T, Minagawa J
    JOURNAL OF BIOLOGICAL CHEMISTRY 287, 31574 (2012).
    DOI: 10.1074/jbc.M111.331991
  • Single-Walled Carbon Nanotubes as Scaffolds to Concentrate DNA for the Study of DNA-Protein Interactions Liu Z, Galli F, Waterreus W, Meulenbroek E, Koning Roman I, Lamers Gerda EM, Olsthoorn René CL, Pannu N, Oosterkamp TjerkH, Koster Abraham J, Dame Remus T, Abrahams J
    CHEMPHYSCHEM 13, 1569 (2012).
    DOI: 10.1002/cphc.201100896
  • Structure of a post-translationally processed heterodimeric double-headed Kunitz-type serine protease inhibitor from potato Meulenbroek Elisabeth M, Thomassen Ellen AJ, Pouvreau L, Abrahams J, Gruppen H, Pannu Navraj S
    ACTA CRYSTALLOGRAPHICA SECTION D - BIOLOGICAL CRYSTALLOGRAPHY 68, 794 (2012).
    DOI: 10.1107/S090744491201222X
  • Supramolecular Non-Amyloid Intermediates in the Early Stages of ?-Synuclein Aggregation Fauerbach Jonathan A, Yushchenko Dmytro A, Shahmoradian Sarah H, Chiu W, Jovin Thomas M, Jares-Erijman Elizabeth A
    BIOPHYSICAL JOURNAL 102, 1127 (2012).
    DOI: 10.1016/j.bpj.2012.01.051
  • Ultra-small graphene oxide functionalized with polyethylenimine (PEI) for very efficient gene delivery in cell and zebrafish embryos Zhou X, Laroche F, Lamers Gerda EM, Torraca V, Voskamp P, Lu T, Chu F, Spaink Herman P, Abrahams J, Liu Z
    Nano Research 5, 703 (2012).
    DOI: 10.1007/s12274-012-0254-x

2011

  • A Straightforward and Robust Method for Introducing Human Hair as a Nucleant into High Throughput Crystallization Trials Nederlof I, Hosseini R, Georgieva D, Luo J, Li D, Abrahams J
    CRYSTAL GROWTH & DESIGN 11, 1170 (2011).
    DOI: 10.1021/cg101374r
  • A direct way of redox sensing Benoit Roger M, Auer Manfred
    RNA BIOLOGY 8, 18-23 (2011).
    DOI: 10.4161/rna.8.1.13555
  • Advances in the CRANK software suite for automated crystal structure solution Waterreus WJ, Skubák P, Sikharulidze I, Abrahams JP, de Graaff RAG, Pannu NS
    Acta Crystallographica Section A Foundations of Crystallography 67, C659 (2011).
    DOI: 10.1107/S0108767311083346
  • Cholesterol attenuates and prevents bilayer damage and breakdown in lipoperoxidized model membranes. A spin labeling EPR study Megli Francesco M, Conte E, Ishikawa T
    Biochimica et Biophysica Acta (BBA) - Biomembranes 1808, 2267 (2011).
    DOI: 10.1016/j.bbamem.2011.04.016
  • Cryoelectron tomography of radial spokes in cilia and flagella Pigino G, Bui K, Maheshwari A, Lupetti P, Diener D, Ishikawa T
    The Journal of Cell Biology 195, 673 (2011).
    DOI: 10.1083/jcb.201106125
  • EDIFF : a program for automated unit-cell determination and indexing of electron diffraction data Jiang L, Georgieva D, Abrahams J
    JOURNAL OF APPLIED CRYSTALLOGRAPHY 44, 1132 (2011).
    DOI: 10.1107/S0021889811030731
  • Electron diffraction of submicron three-dimensional protein crystals Nederlof I, Georgieva D, Abrahams JP
    Acta Crystallographica Section A Foundations of Crystallography 67, C228 (2011).
    DOI: 10.1107/S010876731109430X
  • Evaluation of Medipix2 detector for recording electron diffraction data in low dose conditions Georgieva D, Jansen J, Sikharulidze I, Jiang L, Zandbergen H, Abrahams J
    JOURNAL OF INSTRUMENTATION 6, C01033 (2011).
    DOI: 10.1088/1748-0221/6/01/C01033
  • IMPROVED IMAGING IN LOW ENERGY ELECTRON MICROSCOPY AND PHOTO EMISSION ELECTRON MICROSCOPY USING MEDIPIX2 PIXEL DETECTOR SIKHARULIDZE I, van GASTEL R, SCHRAMM S, ABRAHAMS JP, POELSEMA B, TROM RM, van der MOLEN SJ
    Astroparticle, Particle and Space Physics, Detectors and Medical Physics Applications , (2011).
    DOI: 10.1142/9789814307529_0023
  • Image Processing and Lattice Determination for Three-Dimensional Nanocrystals Jiang L, Georgieva D, Nederlof I, Liu Z, Abrahams J
    MICROSCOPY AND MICROANALYSIS 17, 879 (2011).
    DOI: 10.1017/S1431927611012244
  • Integration of multiple expression cassettes into mammalian genomes in a single step Kriz A, Schmid K, Ballmer K, Berger P
    Protocol Exchange , (2011).
    DOI: 10.1038/protex.2011.249
  • Low energy electron microscopy imaging using Medipix2 detector Sikharulidze I, van Gastel R, Schramm S, Abrahams JP, Poelsema B, Tromp RM, van der Molen SJ
    Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Dectectors and Associated Equipment 633, S239 (2011).
    DOI: 10.1016/j.nima.2010.06.177
  • Low-resolution electron crystallography challenges in organic and inorganic crystals with transmission electron microscope (TEM) Nicolopoulos S, Rauch E, Georgieva D, Abrahams JP
    Acta Crystallographica Section A Foundations of Crystallography 67, C188 (2011).
    DOI: 10.1107/S0108767311095304
  • Neuropilin-1 promotes VEGFR-2 trafficking through Rab11 vesicles thereby specifying signal output Ballmer-Hofer K, Andersson AE, Ratcliffe LE, Berger P
    BLOOD 118, 816 (2011).
    DOI: 10.1182/blood-2011-01-328773
  • RNA polymerase I?specific subunits promote polymerase clustering to enhance the rRNA gene transcription cycle Albert B, Léger-Silvestre I, Normand C, Ostermaier M, Pérez-Fernández J, Panov Kostya I, Zomerdijk Joost CBM, Schultz P, Gadal O
    The Journal of Cell Biology 192, 277 (2011).
    DOI: 10.1083/jcb.201006040
  • Recent advances in the CRANK software suite for experimental phasing Pannu Navraj S, Waterreus W, Skubák P, Sikharulidze I, Abrahams J, de Graaff Rudolf AG
    ACTA CRYSTALLOGRAPHICA SECTION D - BIOLOGICAL CRYSTALLOGRAPHY 67, 331 (2011).
    DOI: 10.1107/S0907444910052224
  • Ribonucleotide reductase inhibition by metal complexes of Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone): A combined experimental and theoretical study Popovic-Bijelic A, Kowol CR, Lind Maria ES, Luo J, Himo F, Enyedy EA, Arion VB, Graeslund A
    JOURNAL OF INORGANIC BIOCHEMISTRY 105, 1422 (2011).
    DOI: 10.1016/j.jinorgbio.2011.07.003
  • The CMT4B disease-causing proteins MTMR2 and MTMR13/SBF2 regulate AKT signalling Berger P, Tersar K, Ballmer-Hofer K, Suter U
    JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 15, 307 (2011).
    DOI: 10.1111/j.1582-4934.2009.00967.x

2010

  • A Graphene Oxide?Streptavidin Complex for Biorecognition - Towards Affinity Purification Liu Z, Jiang L, Galli F, Nederlof I, Olsthoorn René CL, Lamers Gerda EM, Oosterkamp TjerkH, Abrahams J
    ADVANCED FUNCTIONAL MATERIALS 20, 2857 (2010).
    DOI: 10.1002/adfm.201000761
  • A novel approximation method of CTF amplitude correction for 3D single particle reconstruction Jiang L, Liu Z, Georgieva D, Kuil Maxim E, Abrahams J
    ULTRAMICROSCOPY 110, 350 (2010).
    DOI: 10.1016/j.ultramic.2010.01.011
  • A plasmid-based multigene expression system for mammalian cells Kriz A, Schmid K, Baumgartner N, Ziegler U, Berger I, Ballmer-Hofer K, Berger P
    NATURE COMMUNICATIONS 1, 120 (2010).
    DOI: 10.1038/ncomms1120
  • In Silico Analysis of the Apolipoprotein E and the Amyloid ? Peptide Interaction: Misfolding Induced by Frustration of the Salt Bridge Network Luo J, Maréchal J, Wärmländer S, Gräslund A, Perálvarez-Marín A
    PLOS COMPUTATIONAL BIOLOGY 6, e1000663 (2010).
    DOI: 10.1371/journal.pcbi.1000663
  • Nucleotide-induced global conformational changes of flagellar dynein arms revealed by in situ analysis Movassagh T, Bui K, Sakakibara H, Oiwa K, Ishikawa T
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 17, 761 (2010).
    DOI: 10.1038/nsmb.1832
  • Stable Single-Walled Carbon Nanotube-Streptavidin Complex for Biorecognition Liu Z, Galli F, Janssen Kjeld GH, Jiang L, van der Linden Heiko J, de Geus Daniel C, Voskamp P, Kuil Maxim E, Olsthoorn Rene CL, Oosterkamp TjerkH, Hankemeier T, Abrahams J
    JOURNAL OF PHYSICAL CHEMISTRY C 114, 4345 (2010).
    DOI: 10.1021/jp911441d
  • The strong phase object approximation may allow extending crystallographic phases of dynamical electron diffraction patterns of 3D protein nano-crystals Abrahams J
    ZEITSCHRIFT FUR KRISTALLOGRAPHIE 225, (2010).
    DOI: 10.1524/zkri.2010.1216
  • Three-dimensional structural analysis of eukaryotic flagella/cilia by electron cryo-tomography Bui K, Pigino G, Ishikawa T
    JOURNAL OF SYNCHROTRON RADIATION 18, 2 (2010).
    DOI: 10.1107/s0909049510036812

2009

  • An Intelligent Peak Search Program for Digital Electron Diffraction Images of 3D Nano-Crystals Jiang L, Georgieva D, IJspeert K, Abrahams J
    2009 2nd International Congress on Image and Signal Processing , (2009).
    DOI: 10.1109/CISP.2009.5301421
  • Asymmetry of inner dynein arms and inter-doublet links in Chlamydomonas flagella Bui K, Sakakibara H, Movassagh T, Oiwa K, Ishikawa T
    The Journal of Cell Biology 186, 437 (2009).
    DOI: 10.1083/jcb.200903082
  • Automated unrestricted multigene recombineering for multiprotein complex production Bieniossek C, Nie Y, Frey D, Olieric N, Schaffitzel C, Collinson I, Romier C, Berger P, Richmond T, Steinmetz M, Berger I
    NATURE METHODS 6, 447 (2009).
    DOI: 10.1038/nmeth.1326
  • Characterization of a diagnostic Fab fragment binding trimeric Lewis X de Geus Daniël C, van Roon AnneMarie M, Thomassen Ellen AJ, Hokke Cornelis H, Deelder André M, Abrahams J
    PROTEINS: STRUCTURE, FUNCTION, AND BIOINFORMATICS 76, 439 (2009).
    DOI: 10.1002/prot.22356
  • Crystal Structure of Chlorite Dismutase, a Detoxifying Enzyme Producing Molecular Oxygen de Geus Daniël C, Thomassen Ellen AJ, Hagedoorn P, Pannu Navraj S, van Duijn E, Abrahams J
    JOURNAL OF MOLECULAR BIOLOGY 387, 192 (2009).
    DOI: 10.1016/j.jmb.2009.01.036
  • Identification of the variant Ala335Val of MED25 as responsible for CMT2B2: molecular data, functional studies of the SH3 recognition motif and correlation between wild-type MED25 and PMP22 RNA levels in CMT1A animal models Leal A, Huehne K, Bauer F, Sticht H, Berger P, Suter U, Morera B, Del Valle G, Lupski James R, Ekici A, Pasutto F, Endele S, Barrantes R, Berghoff C, Berghoff M, Neundörfer B, Heuss D, Dorn T, Young P, Santolin L, Uhlmann T, Meisterernst M, Sereda M, zu Horste G, Nave K, Reis A, Rautenstrauss B
    NEUROGENETICS 10, 275 (2009).
    DOI: 10.1007/s10048-009-0183-3
  • Involvement of a carboxylated lysine in UV damage endonuclease Meulenbroek Elisabeth M, Paspaleva K, Thomassen Ellen AJ, Abrahams J, Goosen N, Pannu Navraj S
    PROTEIN SCIENCE 18, 549 (2009).
    DOI: 10.1002/pro.54
  • Macromolecular electron crystallography Abrahams J, Jiang L, Sikhuralidze I, Nederloff I, Zandbergen H, Georgieva D
    Acta Crystallographica Section A Foundations of Crystallography 65, s7 (2009).
    DOI: 10.1107/S0108767309099875
  • Mammalian Navigators are microtubule plus-end tracking proteins that can reorganize the cytoskeleton to induce neurite-like extensions van Haren J, Draegestein K, Keijzer N, Abrahams J, Grosveld F, Peeters P, Moechars D, Galjart N
    Cell Motility and the Cytoskeleton 66, 824 (2009).
    DOI: 10.1002/cm.20370
  • Medipix 2 detector applied to low energy electron microscopy van Gastel R, Sikharulidze I, Schramm S, Abrahams JP, Poelsema B, Tromp RM, van der Molen SJ
    ULTRAMICROSCOPY 110, 33 (2009).
    DOI: 10.1016/j.ultramic.2009.09.002
  • Recent advances in CRANK Waterreus W, Pannu N, Skubák P, Sikharulidze I, Abrahams J, de Graaff RAG
    Acta Crystallographica Section A Foundations of Crystallography 65, s160 (2009).
    DOI: 10.1107/S0108767309096743
  • Recycling of Aborted Ribosomal 50S Subunit-Nascent Chain-tRNA Complexes by the Heat Shock Protein Hsp15 Jiang L, Schaffitzel C, Bingel-Erlenmeyer R, Ban N, Korber P, Koning Roman I, de Geus Daniël C, Plaisier Jasper R, Abrahams J
    JOURNAL OF MOLECULAR BIOLOGY 386, 1357 (2009).
    DOI: 10.1016/j.jmb.2008.10.079
  • Terminal Adenosyl Transferase Activity of Posttranscriptional Regulator HuR Revealed by Confocal On-Bead Screening Meisner N, Hintersteiner M, Seifert J, Bauer R, Benoit R, Widmer A, Schindler T, Uhl V, Lang M, Gstach H, Auer M
    JOURNAL OF MOLECULAR BIOLOGY 386, 435 (2009).
    DOI: 10.1016/j.jmb.2008.12.020
  • The Max-Inf2/Lorentz Center workshop on New algorithms in macromolecular crystallography and electron microscopy Pannu Navraj S, Ravelli Raimond BG, Abrahams J
    ACTA CRYSTALLOGRAPHICA SECTION D - BIOLOGICAL CRYSTALLOGRAPHY 65, 623 (2009).
    DOI: 10.1107/S0907444909020861
  • Unit-cell determination from randomly oriented electron-diffraction patterns Jiang L, Georgieva D, Zandbergen Henny W, Abrahams J
    ACTA CRYSTALLOGRAPHICA SECTION D - BIOLOGICAL CRYSTALLOGRAPHY 65, 625 (2009).
    DOI: 10.1107/S0907444909003163

2008

  • Anti-Mullerian-hormone-dependent regulation of the brain serine-protease inhibitor neuroserpin Lebeurrier N, Launay S, Macrez R, Maubert E, Legros H, Leclerc A, Jamin SP, Picard JY, Marret S, Laudenbach V, Berger P, Sonderegger P, Ali C, di Clemente N, Vivien D
    JOURNAL OF CELL SCIENCE 121, 3357 (2008).
    DOI: 10.1242/jcs.031872
  • Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of chlorite dismutase: a detoxifying enzyme producing molecular oxygen de Geus Daniël C, Thomassen Ellen AJ, van der Feltz Clarisse L, Abrahams J
    Acta Crystallographica Section F Structural Biology and Crystallization Communications 64, 730 (2008).
    DOI: 10.1107/S1744309108020551
  • Microtubule Plus-End Conformations and Dynamics in the Periphery of Interphase Mouse Fibroblasts Zovko S, Abrahams JP, Koster AJ, Galjart N, Mommaas AM
    MOLECULAR BIOLOGY OF THE CELL 19, 3138 (2008).
    DOI: 10.1091/mbc.E07-07-0681
  • Molecular architecture of inner dynein arms in situ in Chlamydomonas reinhardtii flagella Bui K, Sakakibara H, Movassagh T, Oiwa K, Ishikawa T
    The Journal of Cell Biology 183, 923 (2008).
    DOI: 10.1083/jcb.200808050
  • Prospects for structure solution by electron diffraction of three-dimensional protein crystals Abrahams JP, Georgieva D, Jiang L, Zandbergen HW
    Acta Crystallographica Section A Foundations of Crystallography 64, C75 (2008).
    DOI: 10.1107/S0108767308097584

2007

  • Crystal Structure of the DNA Repair Enzyme Ultraviolet Damage Endonuclease Paspaleva K, Thomassen E, Pannu Navraj S, Iwai S, Moolenaar Geri F, Goosen N, Abrahams J
    STRUCTURE 15, 1316 (2007).
    DOI: 10.1016/j.str.2007.05.010
  • Cyclops: New modular software suite for cryo-EM Plaisier JR, Jiang L, Abrahams JP
    JOURNAL OF STRUCTURAL BIOLOGY 157, 19 (2007).
    DOI: 10.1016/j.jsb.2006.07.002
  • Early segregation of layered projections from the lateral superior olivary nucleus to the central nucleus of the inferior colliculus in the neonatal cat Gabriele Mark L, Shahmoradian SH, French Christopher C, Henkel Craig K, McHaffie John G
    BRAIN RESEARCH 1173, 66 (2007).
    DOI: 10.1016/j.brainres.2007.07.055
  • Heterogeneous nucleation of three-dimensional protein nanocrystals Georgieva Dilyana G, Kuil Maxim E, Oosterkamp Tjerk H, Zandbergen Henny W, Abrahams J
    ACTA CRYSTALLOGRAPHICA SECTION D - BIOLOGICAL CRYSTALLOGRAPHY 63, 564 (2007).
    DOI: 10.1107/S0907444907007810
  • Mtmr13/Sbf2-deficient mice: an animal model for CMT4B2 Tersar K, Boentert M, Berger P, Bonneick S, Wessig C, Toyka KV, Young P, Suter U
    HUMAN MOLECULAR GENETICS 16, 2991 (2007).
    DOI: 10.1093/hmg/ddm257
  • Multiprotein Expression Strategy for Structural Biology of Eukaryotic Complexes Fitzgerald Daniel J, Schaffitzel C, Berger P, Wellinger R, Bieniossek C, Richmond Timothy J, Berger I
    STRUCTURE 15, 275 (2007).
    DOI: 10.1016/j.str.2007.01.016
  • Recent advances in the CRANK automated structure solution suite Pannu NS, Skubak P, Sikharulidze I, Abrahams JP, de Graaff RAG
    Acta Crystallographica Section A Foundations of Crystallography 63, s116 (2007).
    DOI: 10.1107/S0108767307097516
  • Solving Ab-initio Protein and Nanostructures with Precession Electron Diffraction Georgieva D, Abrahams J, Zandbergen H, Nikolopoulos S, Boulahya K
    MICROSCOPY AND MICROANALYSIS 13, (2007).
    DOI: 10.1017/S1431927607072698
  • Structure of the E. coli signal recognition particle bound to a translating ribosome Schaffitzel C, Oswald M, Berger I, Ishikawa T, Abrahams J, Koerten Henk K, Koning Roman I, Ban N
    NATURE 448, 1076 (2007).
    DOI: 10.1038/nature06169

2006

  • An improved method for fast, robust, and seamless integration of DNA fragments into multiple plasmids Benoit RM, Wilhelm RN, Scherer-Becker D, Ostermeier C
    PROTEIN EXPRESSION AND PURIFICATION 45, 66-71 (2006).
    DOI: 10.1016/j.pep.2005.09.022
  • Multi-level regulation of myotubularin-related protein-2 phosphatase activity by myotubularin-related protein-13/set-binding factor-2 Berger P, Berger I, Schaffitzel C, Tersar K, Volkmer B, Suter U
    HUMAN MOLECULAR GENETICS 15, 569 (2006).
    DOI: 10.1093/hmg/ddi473
  • Nano-dispensing by electrospray for biotechnology Kuil Maxim E, Abrahams J, Marijnissen Jan CM
    Biotechnology Journal 1, 969 (2006).
    DOI: 10.1002/biot.200600062
  • Pathomechanisms of mutant proteins in Charcot-Marie-Tooth disease Niemann A, Berger P, Suter U
    NEUROMOLECULAR MEDICINE 8, 217 (2006).
    DOI: 10.1385/NMM:8:1:217
  • Protein complex expression by using multigene baculoviral vectors Fitzgerald D, Berger P, Schaffitzel C, Yamada K, Richmond T, Berger I
    NATURE METHODS 3, 1021 (2006).
    DOI: 10.1038/nmeth983
  • Schwann cells and the pathogenesis of inherited motor and sensory neuropathies (Charcot-Marie-Tooth disease) Berger P, Niemann A, Suter U
    GLIA 54, 243 (2006).
    DOI: 10.1002/glia.20386
  • Structure of the E. coli signal recognition particle bound to a translating ribosome Schaffitzel C, Oswald M, Berger I, Ishikawa T, Abrahams J, Koerten Henk K, Koning Roman I, Ban N
    NATURE 444, 503 (2006).
    DOI: 10.1038/nature05182
  • The Impact of Single Amino Acid Substitutions in CD3? on the CD3?? Interaction and T-Cell Receptor?CD3 Complex Formation Thomassen EAJ, Dekking EHA, Thompson A, Franken KL, Sanal Ö, Abrahams JP, van Tol MJD, Koning F
    HUMAN IMMUNOLOGY 67, 579 (2006).
    DOI: 10.1016/j.humimm.2006.04.015

2005

  • The protein structure of recombinant human lactoferrin produced in the milk of transgenic cows closely matches the structure of human milk-derived lactoferrin Thomassen Ellen AJ, Veen Harrie Avan, Berkel Patrick HCvan, Nuijens Jan H, Abrahams J
    TRANSGENIC RESEARCH 14, 397 (2005).
    DOI: 10.1007/s11248-005-3233-0

2004

  • CRANK - new methods for automated structure solution Ness S, de Graaff RAG, Abrahams JP, Pannu NS
    Acta Crystallographica Section A Foundations of Crystallography 60, s16 (2004).
    DOI: 10.1107/S0108767304099702
  • Crystal Structure of an Empty Capsid of Turnip Yellow Mosaic Virus van Roon AnneMarie M, Bink Hugo HJ, Plaisier Jasper R, Pleij Cornelis WA, Abrahams J, Pannu Navraj S
    JOURNAL OF MOLECULAR BIOLOGY 341, 1205 (2004).
    DOI: 10.1016/j.jmb.2004.06.085
  • Crystallization and preliminary X-ray crystallographic studies on a Kunitz-type potato serine protease inhibitor Thomassen Ellen AJ, Pouvreau L, Gruppen H, Abrahams J
    ACTA CRYSTALLOGRAPHICA SECTION D - BIOLOGICAL CRYSTALLOGRAPHY 60, 1464 (2004).
    DOI: 10.1107/S0907444904013484
  • Effect of reactive site loop elongation on the inhibitory activity of C1-inhibitor Bos IGA, Lubbers YTP, Eldering E, Abrahams JP, Hack CE
    Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics 1699, 139 (2004).
    DOI: 10.1016/j.bbapap.2004.02.006
  • Relevance of Apoptin's Integrity for Its Functional Behavior Rohn JL, Zhang YH, Leliveld SR, Danen-van Oorschot AAAM, Henriquez NV, Abrahams JP, Noteborn MHM
    JOURNAL OF VIROLOGY 79, 1337 (2004).
    DOI: 10.1128/JVI.79.2.1337-1338.2005
  • Structure of an Anti-Lewis X Fab Fragment in Complex with Its Lewis X Antigen van Roon A, Pannu N, de Vrind Johannes PM, van der Marel G, van Boom J, Hokke C, Deelder A, Abrahams J
    STRUCTURE 12, 1227 (2004).
    DOI: 10.1016/j.str.2004.05.008
  • TYSON: Robust searching, sorting, and selecting of single particles in electron micrographs Plaisier J, Leliveld SR, Kooistraa K, Molenaarc C, Rohan JL, Tanker HJ, Abrahams JP, Noteborn MHM
    JOURNAL OF STRUCTURAL BIOLOGY 145, 76 (2004).
    DOI: 10.1016/j.jsb.2003.09.030

2003

  • ATP-induced conformational changes of the nucleotide-binding domain of Na,K-ATPase Hilge M, Siegal G, Vuister G, Güntert P, Gloor S, Abrahams J
    Nature Structural Biology 10, 468 (2003).
    DOI: 10.1038/nsb924
  • Apoptin protein multimers form distinct higher-order nucleoprotein complexes with DNA Leliveld SR, Dame RT, Kommas MA, Koerten HK, Wyman C, Danen-van Oorschot AAAM, Rohn JL, Noteborn MHM, Abrahams JP
    NUCLEIC ACIDS RESEARCH 31, 4805 (2003).
    DOI: 10.1093/nar/gkg661
  • Apoptin's functional N- and C-termini independently bind DNA Leliveld SR, Dame RT, Rohn JL, Noteborn MHM, Abrahams JP
    FEBS LETTERS 557, 155 (2003).
    DOI: 10.1016/S0014-5793(03)01465-0
  • Area detectors in structural biology Plaisier JR, Koning RI, Koerten HK, Roon AMvan, Thomassen EAJ, Kuil ME, Hendrix J, Broennimann C, Pannu NS, Abrahams JP
    Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Dectectors and Associated Equipment 509, 274 (2003).
    DOI: 10.1016/S0168-9002(03)01638-3
  • Crystallization and preliminary X-ray analysis of an anti-LewisX Fab fragment with and without its LewisX antigen van Roon AnneMarie M, Pannu Navraj S, Hokke Cornelis H, Deelder Andre M, Abrahams J
    ACTA CRYSTALLOGRAPHICA SECTION D - BIOLOGICAL CRYSTALLOGRAPHY 59, 1306 (2003).
    DOI: 10.1107/S0907444903010096
  • Importance of Nuclear Localization of Apoptin for Tumor-specific Induction of Apoptosis Danen-van Oorschot AAAM, Zhang YH, Leliveld SR, Rohn JL, Seelen MCMJ, Bolk MW, van Zon A, Erkeland SJ, Abrahams JP, Mumberg D, Noteborn MHM
    JOURNAL OF BIOLOGICAL CHEMISTRY 278, 27729 (2003).
    DOI: 10.1074/jbc.M303114200
  • Mechanism of Thrombin's Enigmatic Sodium Switch Revealed Abrahams J, Thomassen Ellen AJ
    STRUCTURE 11, 363 (2003).
    DOI: 10.1016/S0969-2126(03)00056-X
  • Prevalent conformations and subunit exchange in the biologically active apoptin protein multimer Leliveld Sirik R, Noteborn Mathieu HM, Abrahams J
    EUROPEAN JOURNAL OF BIOCHEMISTRY 270, 3619 (2003).
    DOI: 10.1046/j.1432-1033.2003.03750.x
  • Recombinant apoptin multimers kill tumor cells but are nontoxic and epitope-shielded in a normal-cell-specific fashion Zhang YH, Leliveld SR, Kooistraa K, Molenaarc C, Rohan JL, Tanker HJ, Abrahams JP, Noteborn MHM
    EXPERIMENTAL CELL RESEARCH 289, 36 (2003).
    DOI: 10.1016/S0014-4827(03)00188-5
  • Structure of ?-Antithrombin and the Effect of Glycosylation on Antithrombin's Heparin Affinity and Activity McCoy Airlie J, Pei X, Skinner R, Abrahams J, Carrell Robin W
    JOURNAL OF MOLECULAR BIOLOGY 326, 823 (2003).
    DOI: 10.1016/S0022-2836(02)01382-7
  • The Functional Integrity of the Serpin Domain of C1-inhibitor Depends on the Unique N-terminal Domain, as Revealed by a Pathological Mutant Bos IGA, Lubbers YTP, Roem D, Abrahams JP, Hack CE, Eldering E
    JOURNAL OF BIOLOGICAL CHEMISTRY 278, 29463 (2003).
    DOI: 10.1074/jbc.M302977200
  • The Structure of the Receptor-binding Domain of the Bacteriophage T4 Short Tail Fibre Reveals a Knitted Trimeric Metal-binding Fold Thomassen E, Gielen G, Schütz M, Schoehn G, Abrahams J, Miller S, van Raaij Mark J
    JOURNAL OF MOLECULAR BIOLOGY 331, 361 (2003).
    DOI: 10.1016/S0022-2836(03)00755-1
  • Visualization by Cryo-electron Microscopy of Genomic RNA that Binds to the Protein Capsid Inside Bacteriophage MS2 Koning R, van den Worm S, Plaisier Jasper R, van Duin J, Abrahams JP, Koerten H
    JOURNAL OF MOLECULAR BIOLOGY 332, 415 (2003).
    DOI: 10.1016/S0022-2836(03)00846-5

2002

  • A novel pH-dependent dimerization motif in ?-lactoglobulin from pig ( Sus scrofa ) Hoedemaeker Flip J, Visschers Ronald W, Alting Arno C, de Kruif Kees G, Kuil Maxim E, Abrahams J
    ACTA CRYSTALLOGRAPHICA SECTION D - BIOLOGICAL CRYSTALLOGRAPHY 58, 480 (2002).
    DOI: 10.1107/S0907444902000616
  • Apoptin Induces Tumor-specific Apoptosis as a Globular Multimer Leliveld SR, Zhang YH, Sohn JL, Noteborn MHM, Abrahams JP
    JOURNAL OF BIOLOGICAL CHEMISTRY 278, 9042 (2002).
    DOI: 10.1074/jbc.M210803200
  • Protein nano-crystallogenesis Kuil M, Bodenstaff ERené, Hoedemaeker F, Abrahams J
    ENZYME AND MICROBIAL TECHNOLOGY 30, 262 (2002).
    DOI: 10.1016/S0141-0229(01)00496-3
  • Screening crystallisation conditions using fluorescence correlation spectroscopy Schmauder R, Schmidt T, Abrahams J, Kuil Maxim E
    ACTA CRYSTALLOGRAPHICA SECTION D - BIOLOGICAL CRYSTALLOGRAPHY 58, 1536 (2002).
    DOI: 10.1107/S0907444902014373
  • Structural and Functional Aspects of C1-Inhibitor Bos I, Hack CE, Abrahams JP
    IMMUNOBIOLOGY 205, 518 (2002).
    DOI: 10.1078/0171-2985-00151
  • The prospects of protein nanocrystallography Bodenstaff ERene, Hoedemaeker Flip J, Kuil Maxim E, de Vrind Hans PM, Abrahams J
    ACTA CRYSTALLOGRAPHICA SECTION D - BIOLOGICAL CRYSTALLOGRAPHY 58, 1901 (2002).
    DOI: 10.1107/S0907444902016608

2001

  • Matrix methods for solving protein substructures of chlorine and sulfur from anomalous data de Graaff Rudolf AG, Hilge M, van der Plas Jaco L, Abrahams J
    ACTA CRYSTALLOGRAPHICA SECTION D - BIOLOGICAL CRYSTALLOGRAPHY 57, 1857 (2001).
    DOI: 10.1107/S0907444901016535
  • Structure elucidation of ?-mannanase: from the electron-density map to the DNA sequence Hilge M, Perrakis A, Abrahams J, Winterhalter K, Piontek K, Gloor Sergio M
    ACTA CRYSTALLOGRAPHICA SECTION D - BIOLOGICAL CRYSTALLOGRAPHY 57, 37 (2001).
    DOI: 10.1107/S0907444900015547

1999

  • Crystal structure of the C-terminal SH2 domain of the p85? regulatory subunit of phosphoinositide 3-kinase: an SH2 domain mimicking its own substrate Hoedemaeker F, Siegal G, Roe SMark, Driscoll P, Abrahams J
    JOURNAL OF MOLECULAR BIOLOGY 292, 763 (1999).
    DOI: 10.1006/jmbi.1999.3111

1998

  • Implications for function and therapy of a 2.9 å structure of binary-complexed antithrombin Skinner R, Chang W, Jin L, Pei X, Huntington J, Abrahams J, Carrell R, Lomas D
    JOURNAL OF MOLECULAR BIOLOGY 283, 9 (1998).
    DOI: 10.1006/jmbi.1998.2083
  • New developments in phase refinement Abrahams J, De Graaff R
    CURRENT OPINION IN STRUCTURAL BIOLOGY 8, 601 (1998).
    DOI: 10.1016/S0959-440X(98)80151-6
  • Wild-type ?1-antitrypsin is in the canonical inhibitory conformation Elliott P, Abrahams J, Lomas D
    JOURNAL OF MOLECULAR BIOLOGY 275, 419 (1998).
    DOI: 10.1006/jmbi.1997.1458

Laboratory of Nanoscale Biology

Secretariat

Anita Strittmatter
Secretary

Paul Scherrer Institut
Department of Biology and Chemistry
OFLC/108
Forschungsstrasse 111
CH-5232 Villigen PSI
Switzerland

Phone: +41 56 310 20 35
Fax: +41 56 310 21 99
anita.strittmatter@psi.ch

BIO Open positions

current opening at Research Division Biology and Chemistry

Directions to PSI

How to get to the Paul Scherrer Institute (description and map)