Dr. Emiliya Poghosyan

Senior scientist
Photo of Emiliya Poghosyan
Telephone
+41 56 310 40 35
Paul Scherrer Institute PSI
Forschungsstrasse 111
5232 Villigen PSI
Switzerland
Digitale Visitenkarte
Education    
Bachelor of Science (with honours) Yerevan State University Physics
Master Degree Technical University of Dresden Nano-biophysics
PhD ETH Zurich Cryo-electron microscopy of motile cilia and flagella
PostDoc University of Basel Single particle cryo-electron microscopy of membrane proteins

 

 

Employment     

2018 - present

PSI

Scientist at the Electron Microscopy Facility:

- user support and education/trainings in basic TEM and cryo-electron microscopy

- managing the facility, equipment troubleshooting

- methods development and implementation for biological electron microscopy
  • Skoupy R, Müller E, Pennycook TJ, Guizar-Sicairos M, Fabbri E, Poghosyan E
    Ptychoscopy: a user friendly experimental design tool for ptychography
    Scientific Reports. 2025; 15(1): 24959 (15 pp.). https://doi.org/10.1038/s41598-025-09871-6
    DORA PSI
  • Aidukas T, Phillips NW, Diaz A, Poghosyan E, Müller E, Levi AFJ, et al.
    High-performance 4-nm-resolution X-ray tomography using burst ptychography
    Nature. 2024; 632(8023): 81-88. https://doi.org/10.1038/s41586-024-07615-6
    DORA PSI
  • Alvarez N, Bruggmann R, Buchmann N, Dessimoz C, Faso C, Hofmann S, et al.
    Biology community roadmap 2024. Update of Swiss community needs for research infrastructures 2029-2032
    Bern: Swiss Academy of Sciences (SCNAT); 2024. Swiss Academies reports: 19/6. https://doi.org/10.5281/zenodo.14264965
    DORA PSI
  • Skoupy R, Grando Stroppa D, Guizar-Sicairos M, Mueller E, Fabbri E, Poghosyan E
    Newcomer's guide into optimal data acquisition for electron ptychography
    In: Celio G, LeBeau J, Evans J, Spurgeon S, Guy N, eds. 2024 proceedings microcospy and microanalysis. Vol. 30. Microscopy and Microanalysis. Oxford University Press; 2024:1846-1847. https://doi.org/10.1093/mam/ozae044.913
    DORA PSI
  • Xie X, Barba Flores L, Bejar Haro B, Bergamaschi A, Fröjdh E, Müller E, et al.
    Enhancing spatial resolution in MÖNCH for electron microscopy via deep learning
    Journal of Instrumentation. 2024; 19(01): C01020 (11 pp.). https://doi.org/10.1088/1748-0221/19/01/C01020
    DORA PSI
  • Collu G, Bierig T, Krebs A-S, Engilberge S, Varma N, Guixà-González R, et al.
    Chimeric single α-helical domains as rigid fusion protein connections for protein nanotechnology and structural biology
    Structure. 2022; 30(1): 95-106. https://doi.org/10.1016/j.str.2021.09.002
    DORA PSI
  • Cvjetinović Đ, Janković D, Milanović Z, Mirković M, Petrović J, Prijović Ž, et al.
    177Lu–labeled micro liposomes as a potential radiosynoviorthesis therapeutic agent
    International Journal of Pharmaceutics. 2021; 608: 121106 (10 pp.). https://doi.org/10.1016/j.ijpharm.2021.121106
    DORA PSI
  • Marelli E, Gazquez J, Poghosyan E, Müller E, Gawryluk DJ, Pomjakushina E, et al.
    Correlation between oxygen vacancies and oxygen evolution reaction activity for a model electrode: PrBaCo2O5+δ
    Angewandte Chemie International Edition. 2021; 60(26): 14609-14619. https://doi.org/10.1002/anie.202103151
    DORA PSI
  • Bierig T, Collu G, Blanc A, Poghosyan E, Benoit RM
    Design, expression, purification, and characterization of a YFP-tagged 2019-n CoV spike receptor-binding domain construct
    Frontiers in Bioengineering and Biotechnology. 2020; 8: 618615 (10 pp.). https://doi.org/10.3389/fbioe.2020.618615
    DORA PSI
  • Poghosyan E, Iacovache I, Faltova L, Leitner A, Yang P, Diener DR, et al.
    The structure and symmetry of the radial spoke protein complex in Chlamydomonas flagella
    Journal of Cell Science. 2020; 133(16): jcs245233 (9 pp.). https://doi.org/10.1242/jcs.245233
    DORA PSI
  • Zhu X, Poghosyan E, Rezabkova L, Mehall B, Sakakibara H, Hirono M, et al.
    The roles of a flagellar HSP40 ensuring rhythmic beating
    Molecular Biology of the Cell. 2019; 30(2): 228-241. https://doi.org/10.1091/mbc.E18-01-0047
    DORA PSI
  • Zhu X, Poghosyan E, Gopal R, Liu Y, Ciruelas KS, Maizy Y, et al.
    General and specific promotion of flagellar assembly by a flagellar nucleoside diphosphate kinase
    Molecular Biology of the Cell. 2017; 28(22): 3029-3042. https://doi.org/10.1091/mbc.E17-03-0156
    DORA PSI

Teaching

2014 - Course instructor at "CIMST summer school on single particle cryo-EM", PSI, Switzerland

2015 - Course instructor at "X-ray crystallography structure determination and biophysics", PSI Switzerland

2016 - Invited instructor and co-organiser at the "7th Brazil School in Single particle cryo-EM", Sao Paulo, Brazil 

2018 - Invited instructor and co-organiser at the "8th Brazil School in Single particle cryo-EM", Sao Paulo, Brazil 

2018 - present - hands on trainings in transmission electron microscopy, cryo-electron tomography and single particle cryo-electron microscopy

2019 - 2021 - Electron Microscopy lectures at PSI and UZH (PHY 427)

Research grants and awards      
DAAD long term fellowship DAAD, Germany 2010 - 2012 Main applicant
PSI research grant PSI (BIO/ENE) 2021 Main applicant 
SDSC collaborative data science project SDSC - PSI 2021  Co-applicant

Member of Swiss Society for Optics and Microscopy (SSOM)