Eukaryotic ribosomes are among the most complex cellular machineries of the cell. These large macromolecular assemblies are responsible for the production of all proteins and are thus of pivotal importance to all forms of life. Two independent research groups at the ETH Zürich and the Institute of Genetics and Molecular and Cellular Biology in Strasbourg have obtained new insights into the atomic structure of the eukaryotic ribosome. The results have been published in the journal Science. All diffraction data were measured with synchrotron light at the Swiss Light Source macromolecular crystallography beamline X06SA at the Paul Scherrer Institute.
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Facility: SLS
Klinge S, Voigts-Hoffmann F, Leibundgut M, Arpagaus S, Ban N.
Science Vol. 334 (6058), 2011 / DOI: 10.1126/science.1211204
The Structure of the Eukaryotic Ribosome at 3.0 A Resolution
Ben-Shem A, Garreau de Loubresse N, Melnikov S, Jenner L, Yusupova G, Yusupov M.
Science 2011 Nov 17 Epub
Swiss Light Source at Paul Scherrer Institut
Phone: +41 56 310 5233
Email: vincent.olieric@psi.ch
Dr. Meitian Wang
Swiss Light Source at Paul Scherrer Institut
Phone: +41 56 310 4175
Email: meitian.wang@psi.ch
Reference
Crystal structure of the eukaryotic 60S ribosomal subunit in complex with initiation factor 6Klinge S, Voigts-Hoffmann F, Leibundgut M, Arpagaus S, Ban N.
Science Vol. 334 (6058), 2011 / DOI: 10.1126/science.1211204
The Structure of the Eukaryotic Ribosome at 3.0 A Resolution
Ben-Shem A, Garreau de Loubresse N, Melnikov S, Jenner L, Yusupova G, Yusupov M.
Science 2011 Nov 17 Epub
Contact
Dr. Vincent OliericSwiss Light Source at Paul Scherrer Institut
Phone: +41 56 310 5233
Email: vincent.olieric@psi.ch
Dr. Meitian Wang
Swiss Light Source at Paul Scherrer Institut
Phone: +41 56 310 4175
Email: meitian.wang@psi.ch