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Laboratory of Radiochemistry

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Development of radionuclides for innovative radiopharmaceuticals

grup photo

An important component of innovative radiopharmaceuticals, especially in oncology is the availability of alternative radionuclides with optimal decay properties, which allow to improve diagnostic or therapeutic efficiency. Currently a variety of accelerator, reactor (or Spallation Neutron Source) and generator produced radionuclides are developed and produced at PSI. Medical radionuclide must be available with high specific activity and purity. Here the choice of the nuclear reaction and subsequent radiochemical isolation strategy play a key role.

Localization and tracking of radio pharmaceuticals in vivo is performed by single photon emission computed tomography (SPECT) as well as by positron emission tomography (PET). The therapeutic radionuclides are particle emitters that are able to deposit a high quantity of energy in small volumes via a high "linear energy transfer" (LET). Here β-, α and also Auger electron emitters are used or considered to be useful for the therapeutic treatment.

The research group Radionuclide Development is a joint research group of the Laboratory of Radiochemistry and of the Center of Radiopharmaceutical Sciences at PSI. 

 

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  • Head: Nick van der Meulen

Contact

Paul Scherrer Institut
Laboratory of Radiochemistry
Secretariate
OFLB/108

Forschungsstrasse 111
5232 Villigen PSI
Switzerland

Mrs. A. Blattmann
+41 56 310 2401
angela.blattmann@psi.ch

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LRC Annual Reports

The Annual Reports of the LRC contain accounts of ongoing scientific research and provide an overview of the variety of topics investigated in our laboratory. Until 2015, they comprise results achieved within the former Laboratory for Radio- and Environmental Chemistry (LCH).

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Paul Scherrer Institut

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