Laboratory of Nanoscale Biology: Technology Support and Related Research
Building on expertise in micro- and nanofabrication, biointerfaces, cellular engineering and light microscopy we are running and supporting projects in different fields including mechano-genomics and protein crystallography.
We are developing novel tools to monitor and quantify trafficking and signalling of receptor tyrosine kinases and G protein-coupled receptors (GPCRs).
In close collaboration with the macromolecular crystallography group at PSI and the Institute of Polymer Nanotechnology at FHNW, we are developing solid supports for serial protein crystallography at the SLS and at SwissFEL.
Surfaces for application in biomolecular research range from protein patterns on glass and polymers to micro- and nanostructures and templates for replication in biocompatible polymers.
We are developing tools for bio-reated research, including acoustic tweezers for non-invasive intracellular manipulation and an ultrasonic acoustic levitation diffractometer for protein crystallography.