Dr. Christian Matthias Schlepütz

photo of Christian Schlepütz

Beamline Scientist

Paul Scherrer Institute
Forschungsstrasse 111
5232 Villigen PSI

My entire scientific career has been revolving around synchrotron-based structural investigations. Both my diploma in experimental physics and my doctoral thesis were carried out at the Materials Science beamline of the Swiss light source, investigating the atomic structure of thin films and crystal surfaces using Surface X-ray Diffraction, for which I obtained my PhD in experimental physics from the University of Zürich (Switzerland) in 2009. This lead to a postdoctoral research position at the University of Michigan (Ann Arbor, USA), continuing studies using X-ray diffraction and becoming a regular user of the diffraction beamlines at the Advanced Photon Source (APS). In 2011, I became a beamline scientist in the Surface Scattering and Microdiffraction group, Sector 33, of the Advanced Photon Source (APS) at Argonne National Laboratory (Chicago, USA), being involved in the user-operation of two beamlines and developing advanced methods for reciprocal space imaging using area detectors. In 2015, the focus of my research shifted from reciprocal space back to real space, when I returned to Switzerland to rejoin the Swiss Light Source as a new member of the TOMCAT group, devoting my time to exploring the wonders of the 3-dimensional microscopic world in motion.

Resolving dynamic phenomena at the microscale in space and time - that is, in a nutshell, what my current research is all about. The world around us is in constant motion, and most of the macroscopic phenomena we experience are goverened by dynamic processes happening at the microscale. To reveal and understand those complex mechanisms, I develop and use the unique tools and capabilities of the TOMCAT beamline that allow us to collect X-ray tomographic microscopy datasets at unprecendented temporal resolutions to create 4-dimensional microscopic movies. Applications range from geoscience via food-processing, materials testing and complex multiphase flows all the way to biomechanical investigations. The latest speed record at TOMCAT was set at 208 tomographic scans per second (Garcia-Moreno, 2019), while sub-second time-resolutions of up to 20 tomographies per second are routinely available to our user community. Currently, I focus on expanding the range of available sample environments to make these capabilities accessible for an even larger range of applications. In parallel, we are working on implementing real-time reconstruction algorithms to establish a true feedback loop of experiments that are controlled and driven by the observed microscopic response of the sample.

For an extensive overview of all PSI-related publications, we kindly refer you to our online publication repository DORA.

Complete publication list

An up-to-date and complete list of all of my publications can be found on my ResearcherID profile (http://www.researcherid.com/rid/C-4696-2008) or in my ORCID record (http://orcid.org/0000-0002-0485-2708).

List of PSI-related publications (last five years)

  • Blažek M, Žalud M, Kočí P, York A, Schlepütz CM, Stampanoni M, et al.
    Washcoating of catalytic particulate filters studied by time-resolved X–ray tomography
    Chemical Engineering Journal. 2021; 409: 128057 (14 pp.). https://doi.org/10.1016/j.cej.2020.128057
  • Borisova E, Lovric G, Miettinen A, Fardin L, Bayat S, Larsson A, et al.
    Micrometer-resolution X-ray tomographic full-volume reconstruction of an intact post-mortem juvenile rat lung
    Histochemistry and Cell Biology. 2021; 155: 215-226. https://doi.org/10.1007/s00418-020-01868-8
  • Börner S, Dittrich D, Mohlau P, Leyens C, García-Moreno F, Kamm PH, et al.
    In situ observation with x-ray for tentative exploration of laser beam welding processes for aluminum-based alloys
    Journal of Laser Applications. 2021; 33(1): 012026 (7 pp.). https://doi.org/10.2351/7.0000315
  • Hill-Casey F, Hotchkiss T, Hardstone KA, Hitchcock I, Novak V, Schlepütz CM, et al.
    Hyperpolarised xenon MRI and time-resolved X-ray computed tomography studies of structure-transport relationships in hierarchical porous media
    Chemical Engineering Journal. 2021; 405: 126750 (57 pp.). https://doi.org/10.1016/j.cej.2020.126750
  • Marti S, Fusseis F, Butler IB, Schlepütz C, Marone F, Gilgannon J, et al.
    Time-resolved grain-scale 3D imaging of hydrofracturing in halite layers induced by gypsum dehydration and pore fluid pressure buildup
    Earth and Planetary Sciences Letters. 2021; 554: 116679 (12 pp.). https://doi.org/10.1016/j.epsl.2020.116679
  • Saikia E, Läubli NF, Burri JT, Rüggeberg M, Schlepütz CM, Vogler H, et al.
    Kinematics governing mechanotransduction in the sensory hair of the Venus flytrap
    International Journal of Molecular Sciences. 2021; 22(1): 280 (21 pp.). https://doi.org/10.3390/ijms22010280
  • Spurin C, Bultreys T, Rücker M, Garfi G, Schlepütz CM, Novak V, et al.
    The development of intermittent multiphase fluid flow pathways through a porous rock
    Advances in Water Resources. 2021; 150: 103868 (7 pp.). https://doi.org/10.1016/j.advwatres.2021.103868
  • Brodrick EA, Roberts NW, Sumner-Rooney L, Schlepütz CM, How MJ
    Light adaptation mechanisms in the eye of the fiddler crab Afruca tangeri
    Journal of Comparative Neurology. 2020. https://doi.org/10.1002/cne.24973
  • Colombier M, Wadsworth FB, Scheu B, Vasseur J, Dobson KJ, Cáceres F, et al.
    In situ observation of the percolation threshold in multiphase magma analogues
    Bulletin of Volcanology. 2020; 82: 32 (15 pp.). https://doi.org/10.1007/s00445-020-1370-1
  • Cörek E, Rodgers G, Siegrist S, Einfalt T, Detampel P, Schlepütz CM, et al.
    Shedding light on metal-based nanoparticles in zebrafish by computed tomography with micrometer resolution
    Small. 2020; 16(31): 2000746 (10 pp.). https://doi.org/10.1002/smll.202000746
  • Dobson KJ, Allabar A, Bretagne E, Coumans J, Cassidy M, Cimarelli C, et al.
    Quantifying microstructural evolution in moving magma
    Frontiers in Earth Science. 2020; 8: 287 (22 pp.). https://doi.org/10.3389/feart.2020.00287
  • García-Moreno F, Radtke LA, Neu TR, Kamm PH, Klaus M, Schlepütz CM, et al.
    The influence of alloy composition and liquid phase on foaming of Al-Si-Mg alloys
    Metals. 2020; 10(2): 189 (18 pp.). https://doi.org/10.3390/met10020189
  • Guo H, Özparpucu M, Windeisen-Holzhauser E, Schlepütz CM, Quadranti E, Gaan S, et al.
    Struvite mineralized wood as sustainable building material: mechanical and combustion behavior
    ACS Sustainable Chemistry and Engineering. 2020; 8(28): 10402-10412. https://doi.org/10.1021/acssuschemeng.0c01769
  • Marone F, Schlepütz CM, Marti S, Fusseis F, Velásquez-Parra A, Griffa M, et al.
    Time resolved in situ X-ray tomographic microscopy unraveling dynamic processes in geologic systems
    Frontiers in Earth Science. 2020; 7: 346 (20 pp.). https://doi.org/10.3389/feart.2019.00346
  • Spurin C, Bultreys T, Rücker M, Garfi G, Schlepütz CM, Novak V, et al.
    Real-time imaging reveals distinct pore-scale dynamics during transient and equilibrium subsurface multiphase flow
    Water Resources Research. 2020; 56(12): e2020WR028287 (10 pp.). https://doi.org/10.1029/2020WR028287
  • Wagner-Hattler L, Québatte G, Keiser J, Schoelkopf J, Schlepütz CM, Huwyler J, et al.
    Study of drug particle distributions within mini-tablets using synchrotron X-ray microtomography and superpixel image clustering
    International Journal of Pharmaceutics. 2020; 573: 118827 (8 pp.). https://doi.org/10.1016/j.ijpharm.2019.118827
  • van Meer NMME, Cerkvenik U, Schlepütz CM, van Leeuwen JL, Gussekloo SWS
    The ovipositor actuation mechanism of a parasitic wasp and its functional implications
    Journal of Anatomy. 2020; 237(4): 689-703. https://doi.org/10.1111/joa.13216
  • Buurlage J-W, Marone F, Pelt DM, Palenstijn WJ, Stampanoni M, Batenburg KJ, et al.
    Real-time reconstruction and visualisation towards dynamic feedback control during time-resolved tomography experiments at TOMCAT
    Scientific Reports. 2019; 9(1): 18379 (11 pp.). https://doi.org/10.1038/s41598-019-54647-4
  • Chavez Panduro EA, Torsæter M, Gawel K, Bjørge R, Gibaud A, Bonnin A, et al.
    Computed X-ray tomography study of carbonate precipitation in large Portland cement pores
    Crystal Growth and Design. 2019; 19(10): 5850-5857. https://doi.org/10.1021/acs.cgd.9b00864
  • García-Moreno F, Kamm PH, Neu TR, Bülk F, Mokso R, Schlepütz CM, et al.
    Using X-ray tomoscopy to explore the dynamics of foaming metal
    Nature Communications. 2019; 10: 3762 (9 pp.). https://doi.org/10.1038/s41467-019-11521-1
  • Guo H, Luković M, Mendoza M, Schlepütz CM, Griffa M, Xu B, et al.
    Bioinspired struvite mineralization for fire-resistant wood
    ACS Applied Materials and Interfaces. 2019; 11(5): 5427-5434. https://doi.org/10.1021/acsami.8b19967
  • Hussein AE, Senabulya N, Ma Y, Streeter MJV, Kettle B, Dann SJD, et al.
    Laser-wakefield accelerators for high-resolution X-ray imaging of complex microstructures
    Scientific Reports. 2019; 9(1): 3249 (13 pp.). https://doi.org/10.1038/s41598-019-39845-4
  • Ito Parada MY, Schlepütz CM, Rossi RM, Derome D, Carmeliet J
    Two-stage wicking of yarns at the fiber scale investigated by synchrotron X-ray phase-contrast fast tomography
    Textile Research Journal. 2019; 89(23-24): 4967-4979. https://doi.org/10.1177/0040517519843461
  • Lacondemine T, Réthoré J, Maire É, Célarié F, Houizot P, Roux-Langlois C, et al.
    Direct observation of the displacement field and microcracking in a glass by means of X-ray tomography during in situ Vickers indentation experiment
    Acta Materialia. 2019; 179: 424-433. https://doi.org/10.1016/j.actamat.2019.07.053
  • Yokoyama R, Kimura G, Schlepütz CM, Huwyler J, Puchkov M
    Modeling of disintegration and dissolution behavior of mefenamic acid formulation using numeric solution of Noyes-Whitney equation with cellular automata on microtomographic and algorithmically generated surfaces
    Pharmaceutics. 2018; 10(4): 259 (17 pp.). https://doi.org/10.3390/pharmaceutics10040259
  • Zhao Y, Du W, Koe B, Connolley T, Irvine S, Allan PK, et al.
    3D characterisation of the Fe-rich intermetallic phases in recycled Al alloys by synchrotron X-ray microtomography and skeletonisation
    Scripta Materialia. 2018; 146: 321-326. https://doi.org/10.1016/j.scriptamat.2017.12.010
  • Davranoglou L-R, Baňař P, Schlepütz CM, Mortimer B, Taylor GK
    The pregenital abdomen of Enicocephalomorpha and morphological evidence for different modes of communication at the dawn of heteropteran evolution
    Arthropod Structure and Development. 2017; 46(6): 843-868. https://doi.org/10.1016/j.asd.2017.08.006
  • Mokso R, Schlepütz CM, Theidel G, Billich H, Schmid E, Celcer T, et al.
    GigaFRoST: the gigabit fast readout system for tomography
    Journal of Synchrotron Radiation. 2017; 24(6): 1250-1259. https://doi.org/10.1107/S1600577517013522