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Center for Radiopharmaceutical Sciences (CRS)

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Publications

2021

2020

2019

2018

  • Visualisation of interstitial lung disease by molecular imaging of integrin αvβ3 and somatostatin receptor 2 Schniering J, Benešová M, Brunner M, Haller S, Cohrs S, Frauenfelder T, Vrugt B, Feghali-Bostwick CA, Schibli R, Distler O, Mueller C, Maurer B
    ANNALS OF THE RHEUMATIC DISEASES , (2018).
    DOI: annrheumdis-2018-214322
  • Design and Preclinical Evaluation of an Albumin-Binding PSMA Ligand for 64Cu-Based PET Imaging Umbricht CA, Benešová M, Hasler R, Schibli R, van der Meulen NP, Müller C
    MOLECULAR PHARMACEUTICS , (2018).
    DOI: acs.molpharmaceut.8b00712
  • Metabotropic glutamate receptor subtype 5 is altered in LPS-induced murine neuroinflammation model and in the brains of AD and ALS patients Müller Herde A, Schibli R, Weber M, Ametamey SM
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING , (2018).
    DOI: s00259-018-4179-9
  • In Vivo Labeling of Plasma Proteins for Imaging of Enhanced Vascular Permeability in the Lungs Schniering J, Borgna F, Siwowska K, Benešová M, Cohrs S, Hasler R, van der Meulen NP, Maurer B, Schibli R, Müller C
    MOLECULAR PHARMACEUTICS 15, 4995 (2018).
    DOI: acs.molpharmaceut.8b00606
  • Combination of lutetium-177 labelled anti-L1CAM antibody chCE7 with the clinically relevant protein kinase inhibitor MK1775: a novel combination against human ovarian carcinoma Lindenblatt D, Terraneo N, Pellegrini G, Cohrs S, Spycher PR, Vukovic D, Béhé M, Schibli R, Grünberg J
    BMC CANCER 18, 922 (2018).
    DOI: s12885-018-4836-1
  • Ketamine and Ceftriaxone-Induced Alterations in Glutamate Levels Do Not Impact the Specific Binding of Metabotropic Glutamate Receptor Subtype 5 Radioligand [18F]PSS232 in the Rat Brain Müller Herde A, Boss SD, He Y, Schibli R, Mu L, Ametamey SM
    PHARMACEUTICASL (BASEL) E83, (2018).
    DOI: ph11030083
  • Evaluation of 99mTc-rhAnnexin V-128 SPECT/CT as a diagnostic tool for early stages of interstitial lung disease associated with systemic sclerosis Schniering J, Guo L, Brunner M, Schibli R, Ye S, Distler O, Béhé M, Maurer B
    ATHRITIS RESEARCH AND THERAPY 20, 183 (2018).
    DOI: s13075-018-1681-1
  • Identification and Preclinical Evaluation of a Radiofluorinated Benzazepine Derivative for Imaging the GluN2B Subunit of the Ionotropic NMDA Receptor Haider A, Iten I, Ahmed H, Müller Herder A, Gruber S, Krämer SD, Keller C, Schibli R, Wünsch B, Mu L, Ametamey SM
    JOURNAL OF NUCLEAR MEDICINE , (2018).
    DOI: jnumed.118.212134
  • Physiologically Based Pharmacokinetic Modelling with Dynamic PET Data to Study the In Vivo Effects of Transporter Inhibition on Hepatobiliary Clearance in Mice Taddio MF, Mu L, Keller C, Schibli R, Krämer SD
    CONTRAST MEDIA AND MOLECULAR IMAGING 5849047, (2018).
    DOI: 5849047
  • Unexpected reactivity of cyclic perfluorinated iodanes with electrophiles Gruber S, Ametamey SM , Schibli R
    CHEMICAL COMMUNICATIONS 54, 8999 (2018).
    DOI: c8cc04558e
  • Diastereomerically Pure 6R- and 6S-3'-aza-2'-18F-Fluoro-5-Methyltetrahydrofolates Show Unprecedented High Uptake in Folate Receptor-positive KB Tumors Boss SD, Müller C, Siwowska K, Schmid RM, Groehn V, Schibli R, Ametamey SM
    JOURNAL OF NUCLEAR MEDICINE , (2018).
    DOI: jnumed.118.213314
  • Pharmacological upregulation of prostate-specific membrane antigen (PSMA) expression in prostate cancer cells Kranzbühler B, Salemi S, Umbricht CA, Müller C, Burger IA, Sulser T, Eberli D
    PROSTATE 78, 758 (2018).
    DOI: pros.23522
  • Combining Albumin-Binding Properties and Interaction with Pemetrexed to Improve the Tissue Distribution of Radiofolates Müller C, Guzik P, Siwowska K, Cohrs S, Schmid RM, Schibli R
    MOLECULES 23, E1465 (2018).
    DOI: molecules23061465
  • Scandium and terbium radionuclides for radiotheranostics: current state of development towards clinical application Müller C, Domnanich KA, Umbricht CA, van der Meulen NP
    BRITISH JOURNAL OF RADIOLOGY , (2018).
    DOI: bjr.20180074
  • Preclinical Development of Novel PSMA-Targeting Radioligands: Modulation of Albumin-Binding Properties To Improve Prostate Cancer Therapy Umbricht CA, Benešová M, Schibli R, Müller C
    MOLECULAR PHARMACEUTICALS , (2018).
    DOI: acs.molpharmaceut.8b00152
  • Injected Human Muscle Precursor Cells Overexpressing PGC-1α Enhance Functional Muscle Regeneration after Trauma Haralampieva D, Salemi S, Betzel T, Dinulovic I, Krämer SD, Schibli R, Sulser T, Handschin C, Ametamey SM, Eberli D
    STEM CELL INTERNATIONAL 2018, 465850 (2018).
    DOI: 4658503
  • Radiosynthesis and evaluation of an 18F-labeled silicon containing exendin-4 peptide as a PET probe for imaging insulinoma Dialer LO, Jodal A, Schibli R, Ametamey SM, Béhé M
    EJNMMI RADIOPHARMACY AND CHEMISTRY 3, 1 (2018).
    DOI: s41181-017-0036-6
  • Improved Syntheses of the Mglu₅ Antagonists MMPEP and MTEP Using Sonogashira Cross-Coupling Mu B, Mu L, Schibli R, Ametamey SM, Milicevic Sephton S
    PHARMACEUTICALS (BASEL) 11, E24 (2018).
    DOI: ph11010024
  • Evaluation of 4-oxo-quinoline-based CB2 PET radioligands in R6/2 chorea huntington mouse model and human ALS spinal cord tissue Haider A, Spinelli F, Herde AM, Mu B, Keller C, Margelisch M, Weber M, Schibli R, Mu L, Ametamey SM
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 145, 746 (2018).
    DOI: j.ejmech.2017.12.097
  • Evaluation of 11C-Me-NB1 as a Potential PET Radioligand for Measuring GluN2B-Containing NMDA Receptors, Drug Occupancy, and Receptor Cross Talk Krämer SD, Betzel T, Mu L, Haider A, Herde AM, Boninsegni AK, Keller C, Szermerski M, Schibli R, Wünsch B, Ametamey SM
    JOURNAL OF NUCLEAR MEDICINE 59, 698 (2018).
    DOI: jnumed.117.200451
  • A first-in-man PET study of [18F]PSS232, a fluorinated ABP688 derivative for imaging metabotropic glutamate receptor subtype 5 Warnock G, Sommerauer M, Mu L, Pla Gonzalez G, Geistlich S, Treyer V, Schibli R, Buck A, Krämer SD, Ametamey SM
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 45, 1041 (2018).
    DOI: s00259-017-3879-x
  • Imaging of Folate Receptor Expressing Macrophages in the Rat Groove Model of Osteoarthritis: Using a New DOTA-Folate Conjugate de Visser HM, Korthagen NM, Müller C, Ramakers RM, Krijger GC, Lafeber FPJG, Beekman FJ, Mastbergen SC, Weinans H
    CARTILAGE 9, 183 (2018).
    DOI: 1947603517738073
  • Albumin-Binding PSMA Ligands: Optimization of the Tissue Distribution Profile Benešová M, Umbricht CA, Schibli R, Müller C
    MOLECULAR PHARMACEUTICS 15, 934 (2018).
    DOI: acs.molpharmaceut.7b00877
  • Reduced 18F-Folate Conjugates as a New Class of PET Tracers for Folate Receptor Imaging Boss SD, Müller C, Siwowska K, Büchel JI, Schmid RM, Groehn V, Schibli R, Ametamey SM
    BIOCONJUGATE CHEMISTRY 29, 1119 (2018).
    DOI: acs.bioconjchem.7b00775

2017

  • Metabotropic glutamate receptor 5 binding in male patients with alcohol use disorder Akkus F, Mihov Y, Treyer V, Ametamey SM, Johayem A, Senn S, Rösner S, Buck A, Hasler G
    TRANSLATIONAL PSYCHIATRY 8, 17 (2017).
    DOI: s41398-017-0066-6
  • Imaging the glutamate receptor subtypes-Much achieved, and still much to do Gruber S, Ametamey SM
    DRUG DISCOVERY TODAY: TECHNOLOGIES 25, 27 (2017).
    DOI: j.ddtec.2017.10.006
  • Radioligands for positron emission tomography imaging of cannabinoid type 2 receptor Spinelli F, Mu L, Ametamey SM
    JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS , (2017).
    DOI: jlcr.3579
  • Cerebral mGluR5 availability contributes to elevated sleep need and behavioral adjustment after sleep deprivation Holst SC, Sousek A, Hefti K, Saberi-Moghadam S, Buck A, Ametamey SM, Scheidegger M, Franken P, Henning A, Seifritz E, Tafti M, Landolt HP
    eLIFE , e28751 (2017).
    DOI: eLife.28751
  • Novel peptide probes to assess the tensional state of fibronectin fibers in cancer Arnoldini S, Moscaroli A, Chabria M, Hilbert M, Hertig S, Schibli R, Béhé M, Vogel V
    NATURE COMMUNICATIONS 8, 1793 (2017).
    DOI: s41467-017-01846-0
  • Towards Translational ImmunoPET/MR Imaging of Invasive Pulmonary Aspergillosis: The Humanised Monoclonal Antibody JF5 Detects Aspergillus Lung Infections In Vivo Davies G, Rolle AM, Maurer A, Spycher PR, Schillinger C, Solouk-Saran D, Hasenberg M, Weski J, Fonslet J, Dubois A, Boschetti F, Denat F, Gunzer M, Eichner M, Ryder LS, Jensen M, Schibli R, Pichler BJ, Wiehr S, Thornton CR
    THERANOSTICS 7, 3398 (2017).
    DOI: thno.20919
  • Synthesis, Radiolabeling, and Characterization of Plasma Protein-Binding Ligands: Potential Tools for Modulation of the Pharmacokinetic Properties of (Radio)Pharmaceuticals Müller C, Farkas R, Borgna F, Schmid RM, Benešová M, Schibli R
    BIOCONJUGATE CHEMISTRY 28, 2372 (2017).
    DOI: acs.bioconjchem.7b00378
  • Therapeutic Radiometals Beyond 177Lu and 90Y: Production and Application of Promising α-Particle, β--Particle, and Auger Electron Emitters Müller C, van der Meulen NP, Benešová M, Schibli R
    JOURNAL OF NUCLEAR MEDICINE 58 (Suppl 2), 91S (2017).
    DOI: jnumed.116.186825
  • Clinical evaluation of the radiolanthanide terbium-152: first-in-human PET/CT with 152Tb-DOTATOC Baum RP, Singh A, Benešová M, Vermeulen C, Gnesin S, Köster U, Johnston K, Müller D, Senftleben S, Kulkarni HR, Türler A, Schibli R, Prior JO, van der Meulen NP, Müller C
    DALTON TRANSACTION 46, 14638 (2017).
    DOI: c7dt01936j
  • Folate Receptor-Positive Gynecological Cancer Cells: In Vitro and In Vivo Characterization Siwowska K, Schmid RM, Cohrs S, Schibli R, Müller C
    PHARMACEUTICALS (BASEL) 10, E72 (2017).
    DOI: ph10030072
  • Dual, Site-Specific Modification of Antibodies by Using Solid-Phase Immobilized Microbial Transglutaminase Spycher PR, Amann CA, Wehrmüller JE, Hurwitz DR, Kreis O, Messmer D, Ritler A,3, Küchler A, Blanc A, Béhé M, Walde P, Schibli R
    CHEMBIOCHEM 18, 1923 (2017).
    DOI: cbic.201700188
  • A Short-Term Biological Indicator for Long-Term Kidney Damage after Radionuclide Therapy in Mice Pellegrini G, Siwowska K, Haller S, Antoine DJ, Schibli R, Kipar A, Müller C
    PHARMACEUTICALS (BASEL) 10, E57 (2017).
    DOI: ph10020057
  • First-in-Human PET/CT Imaging of Metastatic Neuroendocrine Neoplasms with Cyclotron-Produced 44Sc-DOTATOC: A Proof-of-Concept Study Singh A,van der Meulen NP, Müller C, Klette I, Kulkarni HR, Türler A, Schibli R, Baum RP
    CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS 32, 124 (2017).
    DOI: cbr.2016.2173
  • Radiolabeled 111In-FGF-2 Is Suitable for In Vitro/Ex Vivo Evaluations and In Vivo Imaging Moscaroli A, Jones G, Lühmann T, Meinel L, Wälti S, Blanc A, Fischer E, Hilbert M, Schibli R, Béhé M
    MOLECULAR PHARMACEUTICS 14, 639 (2017).
    DOI: acs.molpharmaceut.6b0091
  • Automated cGMP-compliant radiosynthesis of [18 F]-(E)-PSS232 for brain PET imaging of metabotropic glutamate receptor subtype 5 Park JY, Son J, Yun M, Ametamey SM, Chun JH
    JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS , (2017).
    DOI: jlcr.3566
  • Human Muscle Precursor Cells Overexpressing PGC-1α Enhance Early Skeletal Muscle Tissue Formation Haralampieva D, Salemi S, Dinulovic I, Sulser T, Ametamey SM, Handschin C, Eberli D
    CELL TRANSPLANTATION 26, 1103 (2017).
    DOI: 096368917X694868
  • Kinetics of lipid bilayer permeation of a series of ionisable drugs and their correlation with human transporter-independent intestinal permeability Hermann KF, Neuhaus CS, Micallef V, Wagner B, Hatibovic M, Aschmann HE, Paech F, Alvarez-Sanchez R, Krämer SD, Belli S
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 104, 150 (2017).
    DOI: j.ejps.2017.03.040
  • GABAA receptor subtypes in the mouse brain: Regional mapping and diazepam receptor occupancy by in vivo [18F]flumazenil PET Müller Herde A, Benke D, Ralvenius WT, Mu L, Schibli R, Zeilhofer HU, Krämer SD
    NEUROIMAGE 15, 279 (2017).
    DOI: j.neuroimage.2017.02.022
  • Cannabinoid receptor type 2 (CB2) as one of the candidate genes in human carotid plaque imaging: Evaluation of the novel radiotracer [11C]RS-016 targeting CB2 in atherosclerosis Meletta R, Slavik R, Mu L, Rancic Z, Borel N, Schibli R, Ametamey SM, Krämer SD, Müller Herde A
    NUCLEAR MEDICINE AND BIOLOGY 47, 31 (2017).
    DOI: j.nucmedbio.2017.01.001
  • 44Sc-PSMA-617 for radiotheragnostics in tandem with 177Lu-PSMA-617-preclinical investigations in comparison with 68Ga-PSMA-11 and 68Ga-PSMA-617 Umbricht CA, Benešová M, Schmid RM, Türler A, Schibli R, van der Meulen NP, Müller C
    EJNMMI RESEARCH 7, 9 (2017).
    DOI: s13550-017-0257-4
  • Metabotropic glutamate receptor 5 neuroimaging in schizophrenia Akkus F, Treyer V, Ametamey SM, Johayem A, Buck A, Hasler G
    SCHIZOPHRENIA RESEARCH 183, 95 (2017).
    DOI: j.schres.2016.11.008
  • Preclinical Comparison of Albumin-Binding Radiofolates: Impact of Linker Entities on the in Vitro and in Vivo Properties Siwowska K, Haller S, Bortoli F, Benešová M, Groehn V, Bernhardt P, Schibli R, Müller C
    MOLECULAR PHARMACEUTICS 14, 523 (2017).
    DOI: acs.molpharmaceut.6b01010
  • Methoxinine - an alternative stable amino acid substitute for oxidation-sensitive methionine in radiolabelled peptide conjugates Grob NM, Behe M, von Guggenberg E, Schibli R, Mindt TL
    JOURNAL OF PEPTIDE SCIENCE 23, 38 (2017).
    DOI: psc.2948
  • Targets and probes for non-invasive imaging of β-cells Jodal A, Schibli R, Béhé M
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 44, 712 (2017).
    DOI: s00259-016-3592-1

2016

  • 44Sc for labeling of DOTA- and NODAGA functionalized peptides: preclinical in vitro and in vivo investigations Domnanich KA, Müller C, Farkas R, Schmid RM, Ponsard B, Schibli S, Türler A, van der Meulen NP
    EJNMMI RADIOPHARMACY AND CHEMISTRY 1, 5 (2016).
    DOI: s41181-016-0013-5
  • Alpha-PET with terbium-149: evidence and perspectives for radiotheragnostics Müller C, Vermeulen C, Köster U, Johnston K, Türler A, Schibli R, van der Meulen NP
    EJNMMI RADIOPHARMACY AND CHEMISTRY 1, 5 (2016).
    DOI: s41181-016-0008-2
  • Preclinical in vivo application of (152)Tb-DOTANOC: a radiolanthanide for PET imaging Müller C, Vermeulen C, Johnston K, Köster U, Schmid R, Türler A, van der Meulen NP
    EJNMMI RESEARCH 6, 35 (2016).
    DOI: s13550-016-0189-4
  • Evaluation of the first 44Sc-labeled Affibody molecule for imaging of HER2-expressing tumors Honarvar H, Müller C, Cohrs S, Haller S, Westerlund K, Karlström AE, van der Meulen NP, Schibli R, Tolmachev V
    NUCLEAR MEDICINE AND BIOLOGY 45, 15 (2016).
    DOI: j.nucmedbio.2016.10.004
  • Production of (28)Mg by bombardment of (nat)Cl with 200MeV protons: Proof-of-concept study for a stacked LiCl target van der Meulen NP, Steyn GF, Vermeulen C, van Rooyen TJ
    APPLIED RADIATION AND ISOTOPES 115, 125 (2016).
    DOI: j.apradiso.2016.04.026
  • Enhanced sensitivity to drugs of abuse and palatable foods following maternal overnutrition Peleg-Raibstein D, Sarker G, Litwan K, Krämer SD, Ametamey SM, Schibli R, Wolfrum C
    TRANSLATIONAL PSYCHIATRY 6, e911 (2016).
    DOI: tp.2016.176
  • Synthesis and Pharmacological Evaluation of [11C]Granisetron and [18F]Fluoropalonosetron as PET Probes for 5-HT3 Receptor Imaging Mu L, Müller Herde A, Rüefli PM, Sladojevich F, Milicevic Sephton S, Krämer SD, Thompson AJ, Schibli R, Ametamey SM, Lochner M
    ACS CHEMICAL NEUROSCIENCE 7, 1552 (2016).
    DOI: acschemneuro.6b00192
  • Synthesis and Biological Evaluation of Thiophene-Based Cannabinoid Receptor Type 2 Radiotracers for PET Imaging Haider A, Müller Herde A, Slavik R, Weber M, Mugnaini C, Ligresti A, Schibli R, Mu L, Mensah Ametamey S
    FRONTIERS IN NEUROSCIENCE 10, 350 (2016).
    DOI: fnins.2016.00350
  • CD80 Is Upregulated in a Mouse Model with Shear Stress-Induced Atherosclerosis and Allows for Evaluating CD80-Targeting PET Tracers Meletta R, Steier L, Borel N, Mu L, Keller C, Chiotellis A, Russo E, Halin C, Ametamey SM, Schibli R, Krämer SD, Müller Herde A
    MOLUCULAR IMAGING and BIOLOGY Epub ahead of print, (2016).
    DOI: s11307-016-0987-0
  • Discovery of a Fluorinated 4-Oxo-Quinoline Derivative as a Potential PET Radiotracer for Imaging CB2 Receptor Slavik R, Müller Herde A, Haider A, Krämer SD, Weber M, Schibli R, Ametamey SM, Mu L
    JOURNAL OF NEUROCHEMISTRY 138, 874 (2016).
    DOI: jnc.13716
  • Inhibition of MNK pathways enhances cancer cell response to chemotherapy with temozolomide and targeted radionuclide therapy Grzmil M, Seebacher J, Hess D, Behe M, Schibli R, Moncayo G, Frank S, Hemmings BA
    CELLULAR SIGNALLING 28, 1412 (2016).
    DOI: j.cellsig.2016.06.005
  • Non-invasive Imaging and Tracking of Engineered Human Muscle Precursor Cells for Skeletal Muscle Tissue Engineering Using Positron Emission Tomography Haralampieva D, Betzel T, Dinulovic I, Salemi S, Stoelting M, Krämer S, Schibli R, Sulser T, Handschin C, Eberli D, Ametamey SM
    JOURNAL OF NUCLEAR MEDICINE Epub ahead of print, (2016).
    DOI:
  • Synthesis, Radiolabeling, and Biological Evaluation of 5-Hydroxy-2-[(18)F]fluoroalkyl-tryptophan Analogues as Potential PET Radiotracers for Tumor Imaging Chiotellis A, Müller Herde A, Rössler SL, Brekalo A1, Gedeonova E, Mu L, Keller C, Schibli R, Krämer SD, Ametamey SM
    JOURNAL OF MEDICINAL CHEMISTRY 59, 5324 (2016).
    DOI: acs.jmedchem.6b00057
  • (64)Cu- and (68)Ga-Based PET Imaging of Folate Receptor-Positive Tumors: Development and Evaluation of an Albumin-Binding NODAGA-Folate Farkas R, Siwowska K, Ametamey SM, Schibli R, van der Meulen NP, Müller C
    MOLECULAR PHARMACEUTICS 13, 1979 (2016).
    DOI: acs.molpharmaceut.6b00143
  • Novel chemoselective (18)F-radiolabeling of thiol-containing biomolecules under mild aqueous conditions Chiotellis A, Sladojevich F, Mu L, Müller Herde A, Valverde IE, Tolmachev V, Schibli R, Ametamey SM, Mindt TL
    CHEMICAL COMMUNICATION 52, 6083 (2016).
    DOI: c6cc01982j
  • Contribution of Auger/conversion electrons to renal side effects after radionuclide therapy: preclinical comparison of (161)Tb-folate and (177)Lu-folate Haller S, Pellegrini G, Vermeulen C, van der Meulen NP, Köster U, Bernhardt P, Schibli R, Müller C
    EJNMMI RESEARCH 1, 13 (2016).
    DOI: s13550-016-0171-1
  • ImmunoPET/MR imaging allows specific detection of Aspergillus fumigatus lung infection in vivo Rolle AM, Hasenberg M, Thornton CR, Solouk-Saran D, Männ L, Weski J, Maurer A, Fischer E, Spycher PR, Schibli R, Boschetti F, Stegemann-Koniszewski S, Bruder D, Severin GW, Autenrieth SE, Krappmann S, Davies G, Pichler BJ, Gunzer M, Wiehr S
    PNAS 113, E1026 (2016).
    DOI: pnas.1518836113
  • Imaging quality of (44)Sc in comparison with five other PET radionuclides using Derenzo phantoms and preclinical PET Bunka M, Müller C, Vermeulen C, Haller S, Türler A, Schibli R, van der Meulen NP
    APPLIED RADIATION AND ISOTOPES 110, 129 (2016).
    DOI: j.apradiso.2016.01.006
  • Preclinical imaging of the co-stimulatory molecules CD80 and CD86 with indium-111-labeled belatacept in atherosclerosis Meletta R, Müller Herde A, Dennler P, Fischer E, Schibli R, Krämer SD
    EJNMMI RESEARCH 6, 1 (2016).
    DOI: s13550-015-0157-4
  • Comparative Studies of Three Pairs of α- and γ-Conjugated Folic Acid Derivatives Labeled with Fluorine-18 Boss SD, Betzel T, Müller C, Fischer CR, Haller S, Reber J, Groehn V, Schibli R, Ametamey SM
    BIOCONJUGATE CHEMISTRY 27, 74 (2016).
    DOI: acs.bioconjchem.5b00644

2015

  • Ex vivo differential phase contrast and magnetic resonance imaging for characterization of human carotid atherosclerotic plaque Meletta R, Borel N, Stolzmann P, Astolfo A, Klohs J, Stampanoni M, Rudin M, Schibli R, Krämer SD, Müller Herde A
    THE INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING 31, 1425 (2015).
    DOI: s10554-015-0706-y
  • Folate receptor-targeted radionuclide therapy: preclinical investigation of anti-tumor effects and potential radionephropathy Haller S, Reber J, Brandt S, Bernhardt P, Groehn V, Schibli R, Müller C
    NUCLEAR MEDICINE AND BIOLOGY 42, 770 (2015).
    DOI: j.nucmedbio.2015.06.006
  • Cyclotron production of (44)Sc: From bench to bedside van der Meulen NP, Bunka M, Domnanich KA, Müller C, Haller S, Vermeulen C, Türler A, Schibli R
    NUCLEAR MEDICINE AND BIOLOGY 42, 745 (2015).
    DOI: j.nucmedbio.2015.05.00
  • Longitudinal in vivo evaluation of bone regeneration by combined measurement of multi-pinhole SPECT and micro-CT for tissue engineering Lienemann PS, Metzger S, Kiveliö AS, Blanc A, Papageorgiou P, Astolfo A, Pinzer BR, Cinelli P, Weber FE, Schibli R, Béhé M, Ehrbar M
    SCIENTIFIC REPORTS 5, 10238 (2015).
    DOI: srep10238 Erratum DOI: srep12391
  • Discovery of a high affinity and selective pyridine analog as a potential positron emission tomography imaging agent for cannabinoid type 2 receptor Slavik R, Grether U, Müller Herde A, Gobbi L, Fingerle J, Ullmer C, Krämer SD, Schibli R, Mu L, Ametamey SM
    JOURNAL OF MEDICINAL CHEMISTRY 58, 4266 (2015).
    DOI: acs.jmedchem.5b00283
  • Evaluation of a Novel Tc-99m Labelled Vitamin B12 Derivative for Targeting Escherichia coli and Staphylococcus aureus In Vitro and in an Experimental Foreign-Body Infection Model Baldoni D, Waibel R, Bläuenstein P, Galli F, Iodice V, Signore A, Schibli R, Trampuz A
    MOLECULAR IMAGING AND BIOLOGY 10, e0123443 (2015).
    DOI: s11307-015-0832-x
  • Evaluation of ¹¹¹in-labelled exendin-4 derivatives containing different meprin β-specific cleavable linkers Jodal A, Pape F, Becker-Pauly C, Maas O, Schibli R, Béhé M
    PLOS ONE 10, e0123443 (2015).
    DOI: journal.pone.0123443
  • Regional cerebral blood flow estimated by early PiB uptake is reduced in mild cognitive impairment and associated with age in an amyloid-dependent manner Gietl AF, Warnock G, Riese F, Kälin AM, Saake A, Gruber E, Leh SE, Unschuld PG, Kuhn FP, Burger C, Mu L, Seifert B, Nitsch RM, Schibli R, Ametamey SM, Buck A, Hock C
    NEUROBIOLOGY OF AGING 36, 1619 (2015).
    DOI: j.neurobiolaging.2014.12.036
  • Microbial transglutaminase and c-myc-tag: a strong couple for the functionalization of antibody-like protein scaffolds from discovery platforms Dennler P, Bailey LK, Spycher PR, Schibli R, Fischer E
    CHEMBIOCHEM 16, 861 (2015).
    DOI: cbic.201500009
  • Dosimetry and first clinical evaluation of the new 18F-radiolabeled bombesin analogue BAY 864367 in patients with prostate cancer Sah BR, Burger IA, Schibli R, Friebe M, Dinkelborg L, Graham K, Borkowski S, Bacher-Stier C, Valencia R, Srinivasan A, Hany TF, Mu L, Wild PJ, Schaefer NG
    JOURNAL OF NUCLEAR MEDICINE 56, 372 (2015).
    DOI: jnumed.114.147116
  • Synthesis and pharmacological evaluation of ¹¹C-labeled piperazine derivative as a PET probe for sigma-2 receptor imaging Selivanova SV, Toscano A, Abate C, Berardi F, Müller A, Krämer SD, Schibli R, Ametamey SM
    NUCLEAR MEDICINE AND BIOLOGY 42, 399 (2015).
    DOI: j.nucmedbio.2014.12.018
  • Evaluation of the radiolabeled boronic acid-based FAP inhibitor MIP-1232 for atherosclerotic plaque imaging Meletta R, Müller Herde A, Chiotellis A, Isa M, Rancic Z, Borel N, Ametamey SM, Krämer SD, Schibli R
    MOLUCULES 20, 2081 (2015).
    DOI: molecules20022081
  • Investigation of the chick embryo as a potential alternative to the mouse for evaluation of radiopharmaceuticals Haller S, Ametamey SM, Schibli R, Müller C
    NUCLEAR MEDICINE AND BIOLOGY 42, 226 (2015).
    DOI: j.nucmedbio.2014.10.010
  • Quantitative positron emission tomography of mGluR5 in rat brain with [(18) F]PSS232 at minimal invasiveness and reduced model complexity Müller Herde A, Keller C, Milicevic Sephton S, Mu L, Schibli R, Ametamey SM, Krämer SD
    JOURNAL OF NEUROCHEMISTRY 133, 330 (2015).
    DOI: jnc.13001
  • Site-Specific Conjugation of Monomethyl Auristatin E to Anti-CD30 Antibodies Improves Their Pharmacokinetics and Therapeutic Index in Rodent Models Lhospice F, Delphine B, Belmant C, Patrick D, Aristeidis C, Fischer E, Laurent G, Bonnafous C, Viaud N, Represa A, Boëdec A, Rispaud Blanc H, Sapet M, Delcambre C, Ingoure S, Savard Chambard S, Schneider N, Paturel C, Schibli R, Romagne F
    MOLECULAR PHARMACEUTICS 12, 1863 (2015).
    DOI: mp500666j
  • Association of Long-Term Nicotine Abstinence with Normal Metabotropic Glutamate Receptor-5 Binding Akkus F, Treyer V, Johayem A, Ametamey SM, Mancilla BG, Sovago J, Buck A, Hasler G
    BIOLOGYCAL PSYCHATRY , (2015).
    DOI: 10.1016/j.biopsych.2015.02.027
  • Synthesis, radiolabeling and evaluation of novel 4-oxo-quinoline derivatives as PET tracers for imaging cannabinoid type 2 receptor Slavik R, Herde AM1, Bieri D, Weber M, Schibli R, Krämer SD, Ametamey SM, Mu L
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 92, 554 (2015).
    DOI: j.ejmech.2015.01.028
  • Folate Receptor-Targeted Multimodality Imaging of Ovarian Cancer in a Novel Syngeneic Mouse Model Ocak M, Gillman AG, Bresee J, Zhang L, Vlad AM, Müller C, Schibli R, Edwards WB, Anderson CJ, Gach HM
    MOLECULAR PHARMACEUTICS 12, 542 (2015).
    DOI: mp500628g
  • Self-assembled gold coating enhances X-ray imaging of alginate microcapsules Qie F, Astolfo A, Wickramaratna M, Behe M, Evans MD, Hughes TC, Hao X, Tan T
    NANOSCALE 7, 2480 (2015).
    DOI: c4nr06692h
  • Excitation functions of natZr + p nuclear processes up to 70 MeV: New measurements and compilation Szelecsényi F, Steyn GF, Kovács Z, Vermeulen C, Nagatsu K, Zhang MR, Suzuki K
    NUCLEAR INSTRUMENTS AND METHODS IN PHYSICS RESEARCH B 343, 173 (2015).
    DOI: j.nimb.2014.11.081
  • Preclinical evaluation and test-retest studies of [(18)F]PSS232, a novel radioligand for targeting metabotropic glutamate receptor 5 (mGlu5) Sephton SM, Herde AM, Mu L, Keller C, Rüdisühli S, Auberson Y, Schibli R, Krämer SD, Ametamey SM
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 42, 128 (2015).
    DOI: s00259-014-2883-7

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Center for Radiopharmaceutical Sciences
Paul Scherrer Institut
OIPA/103
5232 Villigen PSI
Switzerland

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E-mail Office: sandha.keller@psi.ch

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ETH
Prof. Dr. Roger Schibli
Swiss Federal Institute of Technology Zurich
Radiopharmaceutical Sciences
ETH Zurich

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Radiopharmacy
USZ

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