Publications
2021
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Aime S, Al-Qahtani M, Behe M, Bormans G, Carlucci G, DaSilva JN, et al.
Highlight selection of radiochemistry and radiopharmacy developments by editorial board
EJNMMI Radiopharmacy and Chemistry. 2021; 6(1): 13 (19 pp.). https://doi.org/10.1186/s41181-021-00128-x
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Al-Qahtani M, Behe M, Bormans G, Carlucci G, Dasilva J, Decristoforo C, et al.
Highlight selection of radiochemistry and radiopharmacy developments by editorial board (January-June 2020)
EJNMMI Radiopharmacy and Chemistry. 2021; 6(1): 5 (13 pp.). https://doi.org/10.1186/s41181-020-00118-5
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Baum RP, Singh A, Kulkarni HR, Bernhardt P, Rydén T, Schuchardt C, et al.
First-in-human application of terbium-161: a feasibility study using 161Tb-DOTATOC
Journal of Nuclear Medicine. 2021; 62(10): 1391-1397. https://doi.org/10.2967/jnumed.120.258376
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Bernhardt P, Svensson J, Hemmingsson J, van der Meulen NP, Zeevaart JR, Konijnenberg MW, et al.
Dosimetric analysis of the short-ranged particle emitter 161Tb for radionuclide therapy of metastatic prostate cancer
Cancers. 2021; 13(9): 2011 (13 pp.). https://doi.org/10.3390/cancers13092011
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Borgna F, Haller S, Monné Rodriguez JM, Ginj M, Grundler PV, Zeevaart JR, et al.
Combination of terbium-161 with somatostatin receptor antagonists - a potential paradigm shift for the treatment of neuroendocrine neoplasms
European Journal of Nuclear Medicine and Molecular Imaging. 2021. https://doi.org/10.1007/s00259-021-05564-0
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Borgna F, Barritt P, Grundler PV, Talip Z, Cohrs S, Zeevaart JR, et al.
Simultaneous visualization of 161Tb-and 177Lu-labeled somatostatin analogues using dual-isotope SPECT imaging
Pharmaceutics. 2021; 13(4): 536 (13 pp.). https://doi.org/10.3390/pharmaceutics13040536
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Deberle LM, Benešová M, Becker AE, Ratz M, Guzik P, Schibli R, et al.
Novel synthetic strategies enable the efficient development of folate conjugates for cancer radiotheranostics
Bioconjugate Chemistry. 2021; 32(8): 1617-1628. https://doi.org/10.1021/acs.bioconjchem.1c00198
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Duchemin C, Ramos JP, Stora T, Ahmed E, Aubert E, Audouin N, et al.
CERN-MEDICIS: a review since commissioning in 2017
Frontiers in Medicine. 2021; 8: 693682 (11 pp.). https://doi.org/10.3389/fmed.2021.693682
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Durán MT, Juget F, Nedjadi Y, Bochud F, Talip Z, van der Meulen NP, et al.
Ytterbium-175 half-life determination
Applied Radiation and Isotopes. 2021; 176: 109893 (8 pp.). https://doi.org/10.1016/j.apradiso.2021.109893
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Favaretto C, Talip Z, Borgna F, Grundler PV, Dellepiane G, Sommerhalder A, et al.
Cyclotron production and radiochemical purification of terbium-155 for SPECT imaging
EJNMMI Radiopharmacy and Chemistry. 2021; 6: 37 (17 pp.). https://doi.org/10.1186/s41181-021-00153-w
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Früh SM, Matti U, Spycher PR, Rubini M, Lickert S, Schlichthaerle T, et al.
Site-specifically-labeled antibodies for super-resolution microscopy reveal in situ linkage errors
ACS Nano. 2021; 15(7): 12161-12170. https://doi.org/10.1021/acsnano.1c03677
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Gillings N, Hjelstuen O, Ballinger J, Behe M, Decristoforo C, Elsinga P, et al.
Guideline on current good radiopharmacy practice (cGRPP) for the small-scale preparation of radiopharmaceuticals
EJNMMI Radiopharmacy and Chemistry. 2021; 6(1): 8 (22 pp.). https://doi.org/10.1186/s41181-021-00123-2
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Grob NM, Schibli R, Béhé M, Valverde IE, Mindt TL
1,5-Disubstituted 1,2,3-triazoles as amide bond isosteres yield novel tumor-targeting minigastrin analogs
ACS Medicinal Chemistry Letters. 2021; 12(4): 585-592. https://doi.org/10.1021/acsmedchemlett.0c00636
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Grob NM, Schibli R, Béhé M, Mindt TL
Improved tumor-targeting with peptidomimetic analogs of minigastrin177Lu-PP-F11N
Cancers. 2021; 13(11): 2629 (12 pp.). https://doi.org/10.3390/cancers13112629
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Grzmil M, Imobersteg S, Blanc A, Frank S, Schibli R, Béhé MP
Therapeutic response of CCKBR-positive tumors to combinatory treatment with everolimus and the radiolabeled minigastrin analogue [177Lu]Lu-PP-F11N
Pharmaceutics. 2021; 13(12): 2156 (8 pp.). https://doi.org/10.3390/pharmaceutics13122156
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Guzik P, Fang H-Y, Deberle LM, Benešová M, Cohrs S, Boss SD, et al.
Identification of a PET radiotracer for imaging of the folate receptor-α: a potential tool to select patients for targeted tumor therapy
Journal of Nuclear Medicine. 2021; 62(10): 1475-1481. https://doi.org/10.2967/jnumed.120.255760
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Guzik P, Benešová M, Ratz M, Monné Rodríguez JM, Deberle LM, Schibli R, et al.
Preclinical evaluation of 5-methyltetrahydrofolate-based radioconjugates - new perspectives for folate receptor-targeted radionuclide therapy
European Journal of Nuclear Medicine and Molecular Imaging. 2021; 48: 972-983. https://doi.org/10.1007/s00259-020-04980-y
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Guzik P, Siwowska K, Fang H-Y, Cohrs S, Bernhardt P, Schibli R, et al.
Promising potential of [177Lu]Lu-DOTA-folate to enhance tumor response to immunotherapy - a preclinical study using a syngeneic breast cancer model
European Journal of Nuclear Medicine and Molecular Imaging. 2021; 48: 984-994. https://doi.org/10.1007/s00259-020-05054-9
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Heinke R, Chevallay E, Chrysalidis K, Cocolios TE, Duchemin C, Fedosseev VN, et al.
Efficient production of high specific activity thulium-167 at Paul Scherrer Institute and CERN-MEDICIS
Frontiers in Medicine. 2021; 8: 712374 (17 pp.). https://doi.org/10.3389/fmed.2021.712374
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Juget F, Talip Z, Buchillier T, Durán MT, Nedjadi Y, Desorgher L, et al.
Determination of the gamma and X-ray emission intensities of terbium-161
Applied Radiation and Isotopes. 2021; 174: 109770 (6 pp.). https://doi.org/10.1016/j.apradiso.2021.109770
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Kramer V, Fernández R, Lehnert W, Jiménez-Franco LD, Soza-Ried C, Eppard E, et al.
Biodistribution and dosimetry of a single dose of albumin-binding ligand [177Lu]Lu-PSMA-ALB-56 in patients with mCRPC
European Journal of Nuclear Medicine and Molecular Imaging. 2021; 48: 893-903. https://doi.org/10.1007/s00259-020-05022-3
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Lima TVM, Gnesin S, Strobel K, del Sol Pérez M, Roos JE, Müller C, et al.
Fifty shades of scandium: comparative study of PET capabilities using Sc-43 and Sc-44 with respect to conventional clinical radionuclides
Diagnostics. 2021; 11(10): 1826 (11 pp.). https://doi.org/10.3390/diagnostics11101826
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Romantini N, Alam S, Dobitz S, Spillmann M, De Foresta M, Schibli R, et al.
Exploring the signaling space of a GPCR using bivalent ligands with a rigid oligoproline backbone
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2021; 118(48): e2108776118 (8 pp.). https://doi.org/10.1073/pnas.2108776118
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Taddio MF, Castro Jaramillo CA, Runge P, Blanc A, Keller C, Talip Z, et al.
In vivo imaging of local inflammation: monitoring LPS-induced CD80/CD86 upregulation by PET
Molecular Imaging and Biology. 2021; 23: 196-207. https://doi.org/10.1007/s11307-020-01543-3
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Talip Z, Juget F, Ulrich J, Nedjadi Y, Buchillier T, Durán MT, et al.
Determination of the gamma and X-ray emission intensities of erbium-169
Applied Radiation and Isotopes. 2021; 176: 109823 (9 pp.). https://doi.org/10.1016/j.apradiso.2021.109823
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Talip Z, Borgna F, Müller C, Ulrich J, Duchemin C, Ramos JP, et al.
Production of mass-separated erbium-169 towards the first preclinical in vitro investigations
Frontiers in Medicine. 2021; 8: 643175 (11 pp.). https://doi.org/10.3389/fmed.2021.643175
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Talip Z, Dressler R, Schacherl B, David J-C, Vockenhuber C, Schumann D
Radiochemical determination of long-lived radionuclides in proton-irradiated heavy metal targets: part II tungsten
Analytical Chemistry. 2021; 93(31): 10798-10806. https://doi.org/10.1021/acs.analchem.1c00640
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Tschan VJ, Borgna F, Schibli R, Müller C
Impact of the mouse model and molar amount of injected ligand on the tissue distribution profile of PSMA radioligands
European Journal of Nuclear Medicine and Molecular Imaging. 2021. https://doi.org/10.1007/s00259-021-05446-5
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Wang H, Lallemang M, Hermann B, Wallin C, Loch R, Blanc A, et al.
ATP impedes the inhibitory effect of Hsp90 on Aβ40 fibrillation
Journal of Molecular Biology. 2021; 433(2): 166717 (16 pp.). https://doi.org/10.1016/j.jmb.2020.11.016
DORA PSI
2020
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Alcayne V, Mendoza E, Cano-Ott D, Kimura A, Aberle O, Amaducci S, et al.
Measurement of the 244Cm capture cross sections at both CERN n_TOF experimental areas
In: Ge Z, Shu N, Chen Y, Wang W, Zhang H, eds. ND 2019: international conference on nuclear data for science and technology. Vol. 239. EPJ web of conferences. Sine loco: EDP Science; 2020:01034 (5 pp.). https://doi.org/10.1051/epjconf/202023901034
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Bierig T, Collu G, Blanc A, Poghosyan E, Benoit RM
Design, expression, purification, and characterization of a YFP-tagged 2019-n CoV spike receptor-binding domain construct
Frontiers in Bioengineering and Biotechnology. 2020; 8: 618615 (10 pp.). https://doi.org/10.3389/fbioe.2020.618615
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Borgna F, Deberle LM, Cohrs S, Schibli R, Müller C
Combined application of albumin-binding [177Lu]Lu-PSMA-ALB-56 and fast-cleared PSMA inhibitors: optimization of the pharmacokinetics
Molecular Pharmaceutics. 2020; 17(6): 2044-2053. https://doi.org/10.1021/acs.molpharmaceut.0c00199
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Chiera NM, Talip Z, Fankhauser A, Schumann D
Separation and recovery of exotic radiolanthanides from irradiated tantalum targets for half-life measurements
PLoS One. 2020; 15(7): e0235711 (19 pp.). https://doi.org/10.1371/journal.pone.0235711
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Deberle LM, Tschan VJ, Borgna F, Sozzi-Guo F, Bernhardt P, Schibli R, et al.
Albumin-binding PSMA radioligands: impact of minimal structural changes on the tissue distribution profile
Molecules. 2020; 25(11): 2542 (16 pp.). https://doi.org/10.3390/molecules25112542
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Deberle LM, Benešová M, Umbricht CA, Borgna F, Büchler M, Zhernosekov K, et al.
Development of a new class of PSMA radioligands comprising ibuprofen as an albumin-binding entity
Theranostics. 2020; 10(4): 1678-1693. https://doi.org/10.7150/thno.40482
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Dobitz S, Wilhelm P, Romantini N, De Foresta M, Walther C, Ritler A, et al.
Distance-dependent cellular uptake of oligoproline-based homobivalent ligands targeting GPCRs - an experimental and computational analysis
Bioconjugate Chemistry. 2020; 31(10): 2431-2438. https://doi.org/10.1021/acs.bioconjchem.0c00484
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Dodich A, Mendes A, Assal F, Chicherio C, Rakotomiaramanana B, Andryszak P, et al.
The A/T/N model applied through imaging biomarkers in a memory clinic
European Journal of Nuclear Medicine and Molecular Imaging. 2020; 47(2): 247-255. https://doi.org/10.1007/s00259-019-04536-9
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Durán MT, Juget F, Nedjadi Y, Bochud F, Grundler PV, Gracheva N, et al.
Determination of 161Tb half-life by three measurement methods
Applied Radiation and Isotopes. 2020; 159: 109085 (9 pp.). https://doi.org/10.1016/j.apradiso.2020.109085
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Fonta CM, Arnoldini S, Jaramillo D, Moscaroli A, Oxenius A, Behe M, et al.
Fibronectin fibers are highly tensed in healthy organs in contrast to tumors and virus-infected lymph nodes
Matrix Biology Plus. 2020; 8: 100046 (15 pp.). https://doi.org/10.1016/j.mbplus.2020.100046
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Gnesin S, Müller J, Burger IA, Meisel A, Siano M, Früh M, et al.
Radiation dosimetry of 18F-AzaFol: a first in-human use of a folate receptor PET tracer
EJNMMI Research. 2020; 10(1): 32 (12 pp.). https://doi.org/10.1186/s13550-020-00624-2
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Gracheva N, Carzaniga TS, Schibli R, Braccini S, van der Meulen NP
165Er: a new candidate for Auger electron therapy and its possible cyclotron production from natural holmium targets
Applied Radiation and Isotopes. 2020; 159: 109079 (8 pp.). https://doi.org/10.1016/j.apradiso.2020.109079
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Grob NM, Schmid S, Schibli R, Behe M, Mindt TL
Design of radiolabeled analogs of minigastrin by multiple amide-to-triazole substitutions
Journal of Medicinal Chemistry. 2020; 63(9): 4496-4505. https://doi.org/10.1021/acs.jmedchem.9b01937
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Grob NM, Häussinger D, Deupi X, Schibli R, Behe M, Mindt TL
Triazolo-peptidomimetics: novel radiolabeled minigastrin analogs for improved tumor targeting
Journal of Medicinal Chemistry. 2020; 63(9): 4484-4495. https://doi.org/10.1021/acs.jmedchem.9b01936
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Grundler PV, Eichler R, Talip Z, Schubiger PA, Schibli R, van der Meulen NP
The metamorphosis of radionuclide production and development at Paul Scherrer Institute
Chimia. 2020; 74(12): 968-975. https://doi.org/10.2533/CHIMIA.2020.968
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Grzmil M, Qin Y, Schleuniger C, Frank S, Imobersteg S, Blanc A, et al.
Pharmacological inhibition of mTORC1 increases CCKBR-specific tumor uptake of radiolabeled minigastrin analogue [177Lu]Lu-PP-F11N
Theranostics. 2020; 10(24): 10861-10873. https://doi.org/10.7150/thno.45440
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Lima TVM, Gnesin S, Nitzsche E, Ortega PG, Müller C, van der Meulen NP
First phantom-based quantitative assessment of scandium-44 using a commercial PET device
Frontiers in Physics. 2020; 8: 241 (10 pp.). https://doi.org/10.3389/fphy.2020.00241
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Lühmann T, Gutmann M, Moscaroli A, Raschig M, Béhé M, Meinel L
Biodistribution of site-specific PEGylated fibroblast growth factor-2
ACS Biomaterials Science & Engineering. 2020; 6(1): 425-432. https://doi.org/10.1021/acsbiomaterials.9b01248
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Marin I, Rydèn T, Van Essen M, Svensson J, Gracheva N, Köster U, et al.
Establishment of a clinical SPECT/CT protocol for imaging of 161Tb
EJNMMI Physics. 2020; 7(1): 45 (16 pp.). https://doi.org/10.1186/s40658-020-00314-x
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Mazzone A, Cristallo S, Aberle O, Alaerts G, Alcayne V, Amaducci S, et al.
Measurement of the 154Gd(n,γ) cross section and its astrophysical implications
Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics. 2020; 804: 135405 (6 pp.). https://doi.org/10.1016/j.physletb.2020.135405
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Müller C, Schibli R, Maurer B
Can nuclear imaging of activated macrophages with folic acid-based radiotracers serve as a prognostic means to identify COVID-19 patients at risk?
Pharmaceuticals. 2020; 13(9): 238 (8 pp.). https://doi.org/10.3390/ph13090238
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Müller C, Béhé M, Geistlich S, van der Meulen NP, Schibli R
Targeted radiotherapeutics from 'bench-to-bedside'
Chimia. 2020; 74(12): 939-945. https://doi.org/10.2533/CHIMIA.2020.939
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Nedjadi Y, Juget F, Desorgher L, Durán MT, Bochud F, Müller C, et al.
Activity standardisation of 161Tb
Applied Radiation and Isotopes. 2020; 166: 109411 (13 pp.). https://doi.org/10.1016/j.apradiso.2020.109411
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Nizou G, Favaretto C, Borgna F, Grundler PV, Saffon-Merceron N, Platas-Iglesias C, et al.
Expanding the scope of pyclen-picolinate lanthanide chelates to potential theranostic applications
Inorganic Chemistry. 2020; 59(16): 11736-11748. https://doi.org/10.1021/acs.inorgchem.0c01664
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Oprea A, Gunsing F, Schillebeeckx P, Aberle O, Bacak M, Berthoumieux E, et al.
Neutron capture cross section measurements of 241Am at the n_TOF facility
In: Ge Z, Shu N, Chen Y, Wang W, Zhang H, eds. ND 2019: international conference on nuclear data for science and technology. Vol. 239. EPJ web of conferences. Les Ulis Cedex A: EDP Sciences; 2020:01009 (5 pp.). https://doi.org/10.1051/epjconf/202023901009
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Pamula F, Mühle J, Blanc A, Nehmé R, Edwards PC, Tate CG, et al.
Strategic screening and characterization of the visual GPCR-mini-G protein signaling complex for successful crystallization
Journal of Visualized Experiments. 2020;(157): e60747 (10 pp.). https://doi.org/10.3791/60747
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Pietzsch H-J, Mamat C, Müller C, Schibli R
Single photon emission computed tomography tracer
In: Schober O, Kiessling F, Debus J, eds. Molecular imaging in oncology. Recent results in cancer research. Cham: Springer; 2020:227-282. https://doi.org/10.1007/978-3-030-42618-7_7
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Qin Y, Imobersteg S, Blanc A, Frank S, Schibli R, Béhé MP, et al.
Evaluation of actinium-225 labeled minigastrin analogue [225Ac]Ac-DOTA-PP-F11N for targeted alpha particle therapy
Pharmaceutics. 2020; 12(11): 1088 (12 pp.). https://doi.org/10.3390/pharmaceutics12111088
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Rottenburger C, Nicolas GP, McDougall L, Kaul F, Cachovan M, Vija AH, et al.
Cholecystokinin-2 receptor agonist 177Lu-PP-F11N for radionuclide therapy of medullary thyroid carcinoma - results of the lumed phase 0a study
Journal of Nuclear Medicine. 2020; 61(4): 520-526. https://doi.org/10.2967/jnumed.119.233031
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Rowthu S, Grundler PV, Müller E, Ritter S
Pt catalytic effects on the corrosion and hydrogen chemisorption properties of Zircaloy-2
Journal of Nuclear Materials. 2020; 544: 152716 (15 pp.). https://doi.org/10.1016/j.jnucmat.2020.152716
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Spillmann M, Thurner L, Romantini N, Zimmermann M, Meger B, Behe M, et al.
New insights into arrestin recruitment to GPCRs
International Journal of Molecular Sciences. 2020; 21(14): 4949 (14 pp.). https://doi.org/10.3390/ijms21144949
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Talip Z, Favaretto C, Geistlich S, van der Meulen NP
A step-by-step guide for the novel radiometal production for medical applications: case studies with 68Ga, 44Sc, 177Lu and 161Tb
Molecules. 2020; 25(4): 966 (29 pp.). https://doi.org/10.3390/molecules25040966
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Terraneo N, Jacob F, Peitzsch C, Dubrovska A, Krudewig C, Huang Y-L, et al.
L1 cell adhesion molecule confers radioresistance to ovarian cancer and defines a new cancer stem cell population
Cancers. 2020; 12(1): 217 (17 pp.). https://doi.org/10.3390/cancers12010217
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Terraneo N, Jacob F, Dubrovska A, Grünberg J
Novel therapeutic strategies for ovarian cancer stem cells
Frontiers in Oncology. 2020; 10: 319 (17 pp.). https://doi.org/10.3389/fonc.2020.00319
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Zhang H, Eichler R, Grillenberger J, Hirzel W, Joray S, Kiselev DC, et al.
BDSIM simulation of the complete radionuclide production beam line from beam splitter to target station at the PSI cyclotron facility
In: Conradie L, Garrett De Villiers J, Schaa VRW, eds. CYC2019. 22nd international conference on cyclotrons and their applications. Vol. 22. International conference on cyclotrons and their applications. Geneva: JACoW Publishing; 2020:275-278. https://doi.org/10.18429/JACoW-Cyclotrons2019-WEB04
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van der Meulen NP, Hasler R, Talip Z, Grundler PV, Favaretto C, Umbricht CA, et al.
Developments toward the implementation of 44Sc production at a medical cyclotron
Molecules. 2020; 25(20): 4706 (16 pp.). https://doi.org/10.3390/molecules25204706
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van der Meulen NP, Eichler R, Grundler PV, Hasler R, Hirzel W, Joray S, et al.
The use of PSI's IP2 beam line towards exotic radionuclide development and its application towards proof-of-preclnical and clinical studies
In: Conradie L, Garrett De Villiers J, Schaa VRW, eds. CYC2019. 22nd international conference on cyclotrons and their applications. Vol. 22. International conference on cyclotrons and their applications. Geneva: JACoW Publishing; 2020:132-135. https://doi.org/10.18429/JACoW-Cyclotrons2019-TUA03
DORA PSI
2019
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Alcayne V, Kimura A, Mendoza E, Cano-Ott D, Aberle O, Amaducci S, et al.
Measurement of the 244Cm and 246Cm neutron-induced cross sections at the n_TOF facility
In: García-Ramos J-E, Andrés MV, Pérez-Bernal F, Valera JA, Moro AM, eds. Basic concepts in nuclear physics: theory, experiments and applications. 2018 La Rábida international scientific meeting on nuclear physics. Vol. 225. Springer proceedings in physics. Cham: Springer; 2019:117-122. https://doi.org/10.1007/978-3-030-22204-8_4
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Alcayne V, Kimura A, Mendoza E, Cano-Ott D, Martínez T, Aberle O, et al.
Measurement of the 244Cm and 246Cm neutron-induced capture cross sections at the n_TOF facility
In: Serot O, Chebboubi A, eds. WONDER-2018 - 5th international workshop on nuclear data evaluation for reactor applications. Vol. 211. EPJ web of conferences. sine loco: EDP Sciences; 2019:03008 (8 pp.). https://doi.org/10.1051/epjconf/201921103008
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Babiano-Suarez V, Caballero L, Domingo-Pardo C, Ladarescu I, Aberle O, Alcayne V, et al.
Characterization and first test of an i-TED prototype at CERN n_TOF
In: García-Ramos J-E, Andrés MV, Pérez-Bernal F, Valera JA, Moro AM, eds. Basic concepts in nuclear physics: theory, experiments and applications. 2018 La Rábida international scientific meeting on nuclear physics. Vol. 225. Springer proceedings in physics. Cham: Springer; 2019:169-173. https://doi.org/10.1007/978-3-030-22204-8_18
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Boss SD, Müller C, Siwowska K, Schmid RM, Groehn V, Schibli R, et al.
Diastereomerically pure 6R- and 6S-3'-aza-2'-18F-fluoro-5-methyltetrahydrofolates show unprecedentedly high uptake in folate receptor-positive KB tumors
Journal of Nuclear Medicine. 2019; 60(1): 135-141. https://doi.org/10.2967/jnumed.118.213314
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Brandl F, Merten H, Zimmermann M, Béhé M, Zangemeister-Wittke U, Plückthun A
Influence of size and charge of unstructured polypeptides on pharmacokinetics and biodistribution of targeted fusion proteins
Journal of Controlled Release. 2019; 307: 379-392. https://doi.org/10.1016/j.jconrel.2019.06.030
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Buitinga M, Jansen T, van der Kroon I, Woliner-van der Weg W, Boss M, Janssen M, et al.
Succinylated gelatin improves the theranostic potential of radiolabeled exendin-4 in insulinoma patients
Journal of Nuclear Medicine. 2019; 60(6): 812-816. https://doi.org/10.2967/jnumed.118.219980
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Carzaniga TS, van der Meulen NP, Hasler R, Kottler C, Peier P, Türler A, et al.
Measurement of the 43Sc production cross-section with a deuteron beam
Applied Radiation and Isotopes. 2019; 145: 205-208. https://doi.org/10.1016/j.apradiso.2018.12.031
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Cicone F, Gnesin S, Denoël T, Stora T, van der Meulen NP, Müller C, et al.
Internal radiation dosimetry of a 152Tb-labeled antibody in tumor-bearing mice
EJNMMI Research. 2019; 9: 53 (10 pp.). https://doi.org/10.1186/s13550-019-0524-7
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Gracheva N, Müller C, Talip Z, Heinitz S, Köster U, Zeevaart JR, et al.
Production and characterization of no-carrier-added 161Tb as an alternative to the clinically-applied 177Lu for radionuclide therapy
EJNMMI Radiopharmacy and Chemistry. 2019; 4: 12 (16 pp.). https://doi.org/10.1186/s41181-019-0063-6
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Grünberg J, Terraneo N
L1CAM. Ein vielversprechendes Zellmembranprotein für therapeutische Interventionen
Lead. Opin. Hämatol. Onkolog. 2019:6-8.
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He Y, Mu L, Ametamey SM, Schibli R
Recent progress in allosteric modulators for GluN2A subunit and development of GluN2A-selective nuclear imaging probes
Journal of Labelled Compounds and Radiopharmaceuticals. 2019; 62(8): 552-560. https://doi.org/10.1002/jlcr.3744
DORA PSI -
Iacovacci V, Blanc A, Huang H, Ricotti L, Schibli R, Menciassi A, et al.
High‐resolution SPECT imaging of stimuli‐responsive soft microrobots
Small. 2019; 15(34): 1900709 (7 pp.). https://doi.org/10.1002/smll.201900709
DORA PSI -
Jansen TJP, van Lith SAM, Boss M, Brom M, Joosten L, Béhé M, et al.
Exendin-4 analogs in insulinoma theranostics
Journal of Labelled Compounds and Radiopharmaceuticals. 2019; 62(10): 656-672. https://doi.org/10.1002/jlcr.3750
DORA PSI -
Kaeppeli SAM, Schibli R, Mindt TL, Behe M
Comparison of desferrioxamine and NODAGA for the gallium-68 labeling of exendin-4
EJNMMI Radiopharmacy and Chemistry. 2019; 4(1): 9 (11 pp.). https://doi.org/10.1186/s41181-019-0060-9
DORA PSI -
Kaeppeli SAM, Jodal A, Gotthardt M, Schibli R, Behe M
Exendin-4 derivatives with an albumin-binding moiety show decreased renal retention and improved GLP-1 receptor targeting
Molecular Pharmaceutics. 2019; 16(9): 3760-3769. https://doi.org/10.1021/acs.molpharmaceut.9b00271
DORA PSI -
Kranzbühler B, Salemi S, Umbricht CA, Deberle LM, Müller C, Burger IA, et al.
Concentration‐dependent effects of dutasteride on prostate‐specific membrane antigen (PSMA) expression and uptake of 177Lu‐PSMA‐617 in LNCaP cells
Prostate. 2019; 79(12): 1477-1483. https://doi.org/10.1002/pros.23868
DORA PSI -
Müller C, De Prado Leal M, Dominietto MD, Umbricht CA, Safai S, Perrin RL, et al.
Combination of proton therapy and radionuclide therapy in mice: preclinical pilot sudy at the Paul Scherrer Institute
Pharmaceutics. 2019; 11(9): 450 (13 pp.). https://doi.org/10.3390/pharmaceutics11090450
DORA PSI -
Müller C, Singh A, Umbricht CA, Kulkarni HR, Johnston K, Benešová M, et al.
Preclinical investigations and first-in-human application of 152Tb-PSMA-617 for PET/CT imaging of prostate cancer
EJNMMI Research. 2019; 9(1): 68 (10 pp.). https://doi.org/10.1186/s13550-019-0538-1
DORA PSI -
Müller C, Umbricht CA, Gracheva N, Tschan VJ, Pellegrini G, Bernhardt P, et al.
Terbium-161 for PSMA-targeted radionuclide therapy of prostate cancer
European Journal of Nuclear Medicine and Molecular Imaging. 2019; 46(9): 1919-1930. https://doi.org/10.1007/s00259-019-04345-0
DORA PSI -
Müller Herde A, Schibli R, Weber M, Ametamey SM
Metabotropic glutamate receptor subtype 5 is altered in LPS-induced murine neuroinflammation model and in the brains of AD and ALS patients
European Journal of Nuclear Medicine and Molecular Imaging. 2019; 46(2): 407-420. https://doi.org/10.1007/s00259-018-4179-9
DORA PSI -
Pretze M, van der Meulen N P, Wängler C, Schibli R, Wängler B
Targeted 64Cu-labeled gold nanoparticles for dual imaging with positron emission tomography and optical imaging
Journal of Labelled Compounds and Radiopharmaceuticals. 2019; 62(8): 471-482. https://doi.org/10.1002/jlcr.3736
DORA PSI -
Radford LL, Fernandez S, Beacham R, Sayed RE, Farkas R, Benešová M, et al.
New 55Co-labeled albumin-binding folate derivatives as potential PET agents for folate receptor imaging
Pharmaceuticals. 2019; 12(4): 166 (12 pp.). https://doi.org/10.3390/ph12040166
DORA PSI -
Ritler A, Shoshan MS, Deupi X, Wilhelm P, Schibli R, Wennemers H, et al.
Elucidating the structure−activity relationship of the pentaglutamic acid sequence of minigastrin with cholecystokinin receptor subtype 2
Bioconjugate Chemistry. 2019; 30(3): 657-666. https://doi.org/10.1021/acs.bioconjchem.8b00849
DORA PSI -
Ritter S, Grundler PV, Rowthu S
Assessment of the SCC mitigation capabilities of the NobleChemTM technology in simulated BWR environment
Presented at: ICG-EAC Annual Meeting 2019; May 12-17, 2019; Tainan, Taiwan.
DORA PSI -
Rowthu S, Yeh Y-W, Grundler PV, Holmes R, Ritter S
Assessment of the Pt nanoparticle distribution on oxidized stainless steel surfaces by electrochemical techniques
Presented at: EUROCORR 2019; September 9-13, 2019; Seville, Spain.
DORA PSI -
Rupp NJ, Umbricht CA, Pizzuto DA, Lenggenhager D, Töpfer A, Müller J, et al.
First clinico-pathological evidence of a non PSMA-related uptake mechanism for 68Ga-PSMA-11 in salivary glands
Journal of Nuclear Medicine. 2019; 60(9): 1270-1276. https://doi.org/10.2967/jnumed.118.222307
DORA PSI -
Schniering J, Benešová M, Brunner M, Haller S, Cohrs S, Frauenfelder T, et al.
18F-AzaFol for detection of folate receptor-β positive macrophages in experimental interstitial lung disease - a proof-of-concept study
Frontiers in Immunology. 2019; 10: 2724 (15 pp.). https://doi.org/10.3389/fimmu.2019.02724
DORA PSI -
Siwowska K, Guzik P, Domnanich KA, Monné Rodríguez JM, Bernhardt P, Ponsard B, et al.
Therapeutic potential of 47Sc in comparison to 177Lu and 90Y: preclinical investigations
Pharmaceutics. 2019; 11(8): 424 (13 pp.). https://doi.org/10.3390/pharmaceutics11080424
DORA PSI -
Umbricht CA, Köster U, Bernhardt P, Gracheva N, Johnston K, Schibli R, et al.
Alpha-PET for prostate cancer: preclinical investigation using 149Tb-PSMA-617
Scientific Reports. 2019; 9: 17800 (10 pp.). https://doi.org/10.1038/s41598-019-54150-w
DORA PSI -
Zhang J, Singh A, Kulkarni HR, Schuchardt C, Müller D, Wester H-J, et al.
From bench to bedside—the Bad Berka experience with first-in-human studies
Seminars in Nuclear Medicine. 2019; 49(5): 422-437. https://doi.org/10.1053/j.semnuclmed.2019.06.002
DORA PSI -
van der Meulen NP, Hasler R, Blanc A, Farkas R, Benešová M, Talip Z, et al.
Implementation of a new separation method to produce qualitatively improved 64Cu
Journal of Labelled Compounds and Radiopharmaceuticals. 2019; 62(8): 460-470. https://doi.org/10.1002/jlcr.3730
DORA PSI
2018
- Visualisation of interstitial lung disease by molecular imaging of integrin αvβ3 and somatostatin receptor 2
ANNALS OF THE RHEUMATIC DISEASES , (2018).DOI: annrheumdis-2018-214322
- Design and Preclinical Evaluation of an Albumin-Binding PSMA Ligand for 64Cu-Based PET Imaging
MOLECULAR PHARMACEUTICS , (2018).DOI: acs.molpharmaceut.8b00712
- Metabotropic glutamate receptor subtype 5 is altered in LPS-induced murine neuroinflammation model and in the brains of AD and ALS patients
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING , (2018).DOI: s00259-018-4179-9
- In Vivo Labeling of Plasma Proteins for Imaging of Enhanced Vascular Permeability in the Lungs
MOLECULAR PHARMACEUTICS 15, 4995 (2018).DOI: acs.molpharmaceut.8b00606
- Combination of lutetium-177 labelled anti-L1CAM antibody chCE7 with the clinically relevant protein kinase inhibitor MK1775: a novel combination against human ovarian carcinoma
BMC CANCER 18, 922 (2018).DOI: s12885-018-4836-1
- Ketamine and Ceftriaxone-Induced Alterations in Glutamate Levels Do Not Impact the Specific Binding of Metabotropic Glutamate Receptor Subtype 5 Radioligand [18F]PSS232 in the Rat Brain
PHARMACEUTICASL (BASEL) E83, (2018).DOI: ph11030083
- Evaluation of 99mTc-rhAnnexin V-128 SPECT/CT as a diagnostic tool for early stages of interstitial lung disease associated with systemic sclerosis
ATHRITIS RESEARCH AND THERAPY 20, 183 (2018).DOI: s13075-018-1681-1
- Identification and Preclinical Evaluation of a Radiofluorinated Benzazepine Derivative for Imaging the GluN2B Subunit of the Ionotropic NMDA Receptor
JOURNAL OF NUCLEAR MEDICINE , (2018).DOI: jnumed.118.212134
- Physiologically Based Pharmacokinetic Modelling with Dynamic PET Data to Study the In Vivo Effects of Transporter Inhibition on Hepatobiliary Clearance in Mice
CONTRAST MEDIA AND MOLECULAR IMAGING 5849047, (2018).DOI: 5849047
- Unexpected reactivity of cyclic perfluorinated iodanes with electrophiles
CHEMICAL COMMUNICATIONS 54, 8999 (2018).DOI: c8cc04558e
- Diastereomerically Pure 6R- and 6S-3'-aza-2'-18F-Fluoro-5-Methyltetrahydrofolates Show Unprecedented High Uptake in Folate Receptor-positive KB Tumors
JOURNAL OF NUCLEAR MEDICINE , (2018).DOI: jnumed.118.213314
- Pharmacological upregulation of prostate-specific membrane antigen (PSMA) expression in prostate cancer cells
PROSTATE 78, 758 (2018).DOI: pros.23522
- Combining Albumin-Binding Properties and Interaction with Pemetrexed to Improve the Tissue Distribution of Radiofolates
MOLECULES 23, E1465 (2018).DOI: molecules23061465
- Scandium and terbium radionuclides for radiotheranostics: current state of development towards clinical application
BRITISH JOURNAL OF RADIOLOGY , (2018).DOI: bjr.20180074
- Preclinical Development of Novel PSMA-Targeting Radioligands: Modulation of Albumin-Binding Properties To Improve Prostate Cancer Therapy
MOLECULAR PHARMACEUTICALS , (2018).DOI: acs.molpharmaceut.8b00152
- Injected Human Muscle Precursor Cells Overexpressing PGC-1α Enhance Functional Muscle Regeneration after Trauma
STEM CELL INTERNATIONAL 2018, 465850 (2018).DOI: 4658503
- Radiosynthesis and evaluation of an 18F-labeled silicon containing exendin-4 peptide as a PET probe for imaging insulinoma
EJNMMI RADIOPHARMACY AND CHEMISTRY 3, 1 (2018).DOI: s41181-017-0036-6
- Improved Syntheses of the Mglu₅ Antagonists MMPEP and MTEP Using Sonogashira Cross-Coupling
PHARMACEUTICALS (BASEL) 11, E24 (2018).DOI: ph11010024
- Evaluation of 4-oxo-quinoline-based CB2 PET radioligands in R6/2 chorea huntington mouse model and human ALS spinal cord tissue
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 145, 746 (2018).DOI: j.ejmech.2017.12.097
- Evaluation of 11C-Me-NB1 as a Potential PET Radioligand for Measuring GluN2B-Containing NMDA Receptors, Drug Occupancy, and Receptor Cross Talk
JOURNAL OF NUCLEAR MEDICINE 59, 698 (2018).DOI: jnumed.117.200451
- A first-in-man PET study of [18F]PSS232, a fluorinated ABP688 derivative for imaging metabotropic glutamate receptor subtype 5
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 45, 1041 (2018).DOI: s00259-017-3879-x
- Imaging of Folate Receptor Expressing Macrophages in the Rat Groove Model of Osteoarthritis: Using a New DOTA-Folate Conjugate
CARTILAGE 9, 183 (2018).DOI: 1947603517738073
- Albumin-Binding PSMA Ligands: Optimization of the Tissue Distribution Profile
MOLECULAR PHARMACEUTICS 15, 934 (2018).DOI: acs.molpharmaceut.7b00877
- Reduced 18F-Folate Conjugates as a New Class of PET Tracers for Folate Receptor Imaging
BIOCONJUGATE CHEMISTRY 29, 1119 (2018).DOI: acs.bioconjchem.7b00775
2017
- Metabotropic glutamate receptor 5 binding in male patients with alcohol use disorder
TRANSLATIONAL PSYCHIATRY 8, 17 (2017).DOI: s41398-017-0066-6
- Imaging the glutamate receptor subtypes-Much achieved, and still much to do
DRUG DISCOVERY TODAY: TECHNOLOGIES 25, 27 (2017).DOI: j.ddtec.2017.10.006
- Radioligands for positron emission tomography imaging of cannabinoid type 2 receptor
JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS , (2017).DOI: jlcr.3579
- Cerebral mGluR5 availability contributes to elevated sleep need and behavioral adjustment after sleep deprivation
eLIFE , e28751 (2017).DOI: eLife.28751
- Novel peptide probes to assess the tensional state of fibronectin fibers in cancer
NATURE COMMUNICATIONS 8, 1793 (2017).DOI: s41467-017-01846-0
- Towards Translational ImmunoPET/MR Imaging of Invasive Pulmonary Aspergillosis: The Humanised Monoclonal Antibody JF5 Detects Aspergillus Lung Infections In Vivo
THERANOSTICS 7, 3398 (2017).DOI: thno.20919
- Synthesis, Radiolabeling, and Characterization of Plasma Protein-Binding Ligands: Potential Tools for Modulation of the Pharmacokinetic Properties of (Radio)Pharmaceuticals
BIOCONJUGATE CHEMISTRY 28, 2372 (2017).DOI: acs.bioconjchem.7b00378
- Therapeutic Radiometals Beyond 177Lu and 90Y: Production and Application of Promising α-Particle, β--Particle, and Auger Electron Emitters
JOURNAL OF NUCLEAR MEDICINE 58 (Suppl 2), 91S (2017).DOI: jnumed.116.186825
- Clinical evaluation of the radiolanthanide terbium-152: first-in-human PET/CT with 152Tb-DOTATOC
DALTON TRANSACTION 46, 14638 (2017).DOI: c7dt01936j
- Folate Receptor-Positive Gynecological Cancer Cells: In Vitro and In Vivo Characterization
PHARMACEUTICALS (BASEL) 10, E72 (2017).DOI: ph10030072
- Dual, Site-Specific Modification of Antibodies by Using Solid-Phase Immobilized Microbial Transglutaminase
CHEMBIOCHEM 18, 1923 (2017).DOI: cbic.201700188
- A Short-Term Biological Indicator for Long-Term Kidney Damage after Radionuclide Therapy in Mice
PHARMACEUTICALS (BASEL) 10, E57 (2017).DOI: ph10020057
- First-in-Human PET/CT Imaging of Metastatic Neuroendocrine Neoplasms with Cyclotron-Produced 44Sc-DOTATOC: A Proof-of-Concept Study
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS 32, 124 (2017).DOI: cbr.2016.2173
- Radiolabeled 111In-FGF-2 Is Suitable for In Vitro/Ex Vivo Evaluations and In Vivo Imaging
MOLECULAR PHARMACEUTICS 14, 639 (2017).DOI: acs.molpharmaceut.6b0091
- Automated cGMP-compliant radiosynthesis of [18 F]-(E)-PSS232 for brain PET imaging of metabotropic glutamate receptor subtype 5
JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS , (2017).DOI: jlcr.3566
- Human Muscle Precursor Cells Overexpressing PGC-1α Enhance Early Skeletal Muscle Tissue Formation
CELL TRANSPLANTATION 26, 1103 (2017).DOI: 096368917X694868
- Kinetics of lipid bilayer permeation of a series of ionisable drugs and their correlation with human transporter-independent intestinal permeability
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 104, 150 (2017).DOI: j.ejps.2017.03.040
- GABAA receptor subtypes in the mouse brain: Regional mapping and diazepam receptor occupancy by in vivo [18F]flumazenil PET
NEUROIMAGE 15, 279 (2017).DOI: j.neuroimage.2017.02.022
- Cannabinoid receptor type 2 (CB2) as one of the candidate genes in human carotid plaque imaging: Evaluation of the novel radiotracer [11C]RS-016 targeting CB2 in atherosclerosis
NUCLEAR MEDICINE AND BIOLOGY 47, 31 (2017).DOI: j.nucmedbio.2017.01.001
- 44Sc-PSMA-617 for radiotheragnostics in tandem with 177Lu-PSMA-617-preclinical investigations in comparison with 68Ga-PSMA-11 and 68Ga-PSMA-617
EJNMMI RESEARCH 7, 9 (2017).DOI: s13550-017-0257-4
- Metabotropic glutamate receptor 5 neuroimaging in schizophrenia
SCHIZOPHRENIA RESEARCH 183, 95 (2017).DOI: j.schres.2016.11.008
- Preclinical Comparison of Albumin-Binding Radiofolates: Impact of Linker Entities on the in Vitro and in Vivo Properties
MOLECULAR PHARMACEUTICS 14, 523 (2017).DOI: acs.molpharmaceut.6b01010
- Methoxinine - an alternative stable amino acid substitute for oxidation-sensitive methionine in radiolabelled peptide conjugates
JOURNAL OF PEPTIDE SCIENCE 23, 38 (2017).DOI: psc.2948
- Targets and probes for non-invasive imaging of β-cells
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 44, 712 (2017).DOI: s00259-016-3592-1
2016
- 44Sc for labeling of DOTA- and NODAGA functionalized peptides: preclinical in vitro and in vivo investigations
EJNMMI RADIOPHARMACY AND CHEMISTRY 1, 5 (2016).DOI: s41181-016-0013-5
- Alpha-PET with terbium-149: evidence and perspectives for radiotheragnostics
EJNMMI RADIOPHARMACY AND CHEMISTRY 1, 5 (2016).DOI: s41181-016-0008-2
- Preclinical in vivo application of (152)Tb-DOTANOC: a radiolanthanide for PET imaging
EJNMMI RESEARCH 6, 35 (2016).DOI: s13550-016-0189-4
- Evaluation of the first 44Sc-labeled Affibody molecule for imaging of HER2-expressing tumors
NUCLEAR MEDICINE AND BIOLOGY 45, 15 (2016).DOI: j.nucmedbio.2016.10.004
- Production of (28)Mg by bombardment of (nat)Cl with 200MeV protons: Proof-of-concept study for a stacked LiCl target
APPLIED RADIATION AND ISOTOPES 115, 125 (2016).DOI: j.apradiso.2016.04.026
- Enhanced sensitivity to drugs of abuse and palatable foods following maternal overnutrition
TRANSLATIONAL PSYCHIATRY 6, e911 (2016).DOI: tp.2016.176
- Synthesis and Pharmacological Evaluation of [11C]Granisetron and [18F]Fluoropalonosetron as PET Probes for 5-HT3 Receptor Imaging
ACS CHEMICAL NEUROSCIENCE 7, 1552 (2016).DOI: acschemneuro.6b00192
- Synthesis and Biological Evaluation of Thiophene-Based Cannabinoid Receptor Type 2 Radiotracers for PET Imaging
FRONTIERS IN NEUROSCIENCE 10, 350 (2016).DOI: fnins.2016.00350
- CD80 Is Upregulated in a Mouse Model with Shear Stress-Induced Atherosclerosis and Allows for Evaluating CD80-Targeting PET Tracers
MOLUCULAR IMAGING and BIOLOGY Epub ahead of print, (2016).DOI: s11307-016-0987-0
- Discovery of a Fluorinated 4-Oxo-Quinoline Derivative as a Potential PET Radiotracer for Imaging CB2 Receptor
JOURNAL OF NEUROCHEMISTRY 138, 874 (2016).DOI: jnc.13716
- Inhibition of MNK pathways enhances cancer cell response to chemotherapy with temozolomide and targeted radionuclide therapy
CELLULAR SIGNALLING 28, 1412 (2016).DOI: j.cellsig.2016.06.005
- Non-invasive Imaging and Tracking of Engineered Human Muscle Precursor Cells for Skeletal Muscle Tissue Engineering Using Positron Emission Tomography
JOURNAL OF NUCLEAR MEDICINE Epub ahead of print, (2016).DOI:
- Synthesis, Radiolabeling, and Biological Evaluation of 5-Hydroxy-2-[(18)F]fluoroalkyl-tryptophan Analogues as Potential PET Radiotracers for Tumor Imaging
JOURNAL OF MEDICINAL CHEMISTRY 59, 5324 (2016).DOI: acs.jmedchem.6b00057
- (64)Cu- and (68)Ga-Based PET Imaging of Folate Receptor-Positive Tumors: Development and Evaluation of an Albumin-Binding NODAGA-Folate
MOLECULAR PHARMACEUTICS 13, 1979 (2016).DOI: acs.molpharmaceut.6b00143
- Novel chemoselective (18)F-radiolabeling of thiol-containing biomolecules under mild aqueous conditions
CHEMICAL COMMUNICATION 52, 6083 (2016).DOI: c6cc01982j
- Contribution of Auger/conversion electrons to renal side effects after radionuclide therapy: preclinical comparison of (161)Tb-folate and (177)Lu-folate
EJNMMI RESEARCH 1, 13 (2016).DOI: s13550-016-0171-1
- ImmunoPET/MR imaging allows specific detection of Aspergillus fumigatus lung infection in vivo
PNAS 113, E1026 (2016).DOI: pnas.1518836113
- Imaging quality of (44)Sc in comparison with five other PET radionuclides using Derenzo phantoms and preclinical PET
APPLIED RADIATION AND ISOTOPES 110, 129 (2016).DOI: j.apradiso.2016.01.006
- Preclinical imaging of the co-stimulatory molecules CD80 and CD86 with indium-111-labeled belatacept in atherosclerosis
EJNMMI RESEARCH 6, 1 (2016).DOI: s13550-015-0157-4
- Comparative Studies of Three Pairs of α- and γ-Conjugated Folic Acid Derivatives Labeled with Fluorine-18
BIOCONJUGATE CHEMISTRY 27, 74 (2016).DOI: acs.bioconjchem.5b00644
2015
- Ex vivo differential phase contrast and magnetic resonance imaging for characterization of human carotid atherosclerotic plaque
THE INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING 31, 1425 (2015).DOI: s10554-015-0706-y
- Folate receptor-targeted radionuclide therapy: preclinical investigation of anti-tumor effects and potential radionephropathy
NUCLEAR MEDICINE AND BIOLOGY 42, 770 (2015).DOI: j.nucmedbio.2015.06.006
- Cyclotron production of (44)Sc: From bench to bedside
NUCLEAR MEDICINE AND BIOLOGY 42, 745 (2015).DOI: j.nucmedbio.2015.05.00
- Longitudinal in vivo evaluation of bone regeneration by combined measurement of multi-pinhole SPECT and micro-CT for tissue engineering
SCIENTIFIC REPORTS 5, 10238 (2015).DOI: srep10238 Erratum DOI: srep12391
- Discovery of a high affinity and selective pyridine analog as a potential positron emission tomography imaging agent for cannabinoid type 2 receptor
JOURNAL OF MEDICINAL CHEMISTRY 58, 4266 (2015).DOI: acs.jmedchem.5b00283
- Evaluation of a Novel Tc-99m Labelled Vitamin B12 Derivative for Targeting Escherichia coli and Staphylococcus aureus In Vitro and in an Experimental Foreign-Body Infection Model
MOLECULAR IMAGING AND BIOLOGY 10, e0123443 (2015).DOI: s11307-015-0832-x
- Evaluation of ¹¹¹in-labelled exendin-4 derivatives containing different meprin β-specific cleavable linkers
PLOS ONE 10, e0123443 (2015).DOI: journal.pone.0123443
- Regional cerebral blood flow estimated by early PiB uptake is reduced in mild cognitive impairment and associated with age in an amyloid-dependent manner
NEUROBIOLOGY OF AGING 36, 1619 (2015).DOI: j.neurobiolaging.2014.12.036
- Microbial transglutaminase and c-myc-tag: a strong couple for the functionalization of antibody-like protein scaffolds from discovery platforms
CHEMBIOCHEM 16, 861 (2015).DOI: cbic.201500009
- Dosimetry and first clinical evaluation of the new 18F-radiolabeled bombesin analogue BAY 864367 in patients with prostate cancer
JOURNAL OF NUCLEAR MEDICINE 56, 372 (2015).DOI: jnumed.114.147116
- Synthesis and pharmacological evaluation of ¹¹C-labeled piperazine derivative as a PET probe for sigma-2 receptor imaging
NUCLEAR MEDICINE AND BIOLOGY 42, 399 (2015).DOI: j.nucmedbio.2014.12.018
- Evaluation of the radiolabeled boronic acid-based FAP inhibitor MIP-1232 for atherosclerotic plaque imaging
MOLUCULES 20, 2081 (2015).DOI: molecules20022081
- Investigation of the chick embryo as a potential alternative to the mouse for evaluation of radiopharmaceuticals
NUCLEAR MEDICINE AND BIOLOGY 42, 226 (2015).DOI: j.nucmedbio.2014.10.010
- Quantitative positron emission tomography of mGluR5 in rat brain with [(18) F]PSS232 at minimal invasiveness and reduced model complexity
JOURNAL OF NEUROCHEMISTRY 133, 330 (2015).DOI: jnc.13001
- Site-Specific Conjugation of Monomethyl Auristatin E to Anti-CD30 Antibodies Improves Their Pharmacokinetics and Therapeutic Index in Rodent Models
MOLECULAR PHARMACEUTICS 12, 1863 (2015).DOI: mp500666j
- Association of Long-Term Nicotine Abstinence with Normal Metabotropic Glutamate Receptor-5 Binding
BIOLOGYCAL PSYCHATRY , (2015).DOI: 10.1016/j.biopsych.2015.02.027
- Synthesis, radiolabeling and evaluation of novel 4-oxo-quinoline derivatives as PET tracers for imaging cannabinoid type 2 receptor
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 92, 554 (2015).DOI: j.ejmech.2015.01.028
- Folate Receptor-Targeted Multimodality Imaging of Ovarian Cancer in a Novel Syngeneic Mouse Model
MOLECULAR PHARMACEUTICS 12, 542 (2015).DOI: mp500628g
- Self-assembled gold coating enhances X-ray imaging of alginate microcapsules
NANOSCALE 7, 2480 (2015).DOI: c4nr06692h
- Excitation functions of natZr + p nuclear processes up to 70 MeV: New measurements and compilation
NUCLEAR INSTRUMENTS AND METHODS IN PHYSICS RESEARCH B 343, 173 (2015).DOI: j.nimb.2014.11.081
- Preclinical evaluation and test-retest studies of [(18)F]PSS232, a novel radioligand for targeting metabotropic glutamate receptor 5 (mGlu5)
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 42, 128 (2015).DOI: s00259-014-2883-7