News & Scientific Highlights
Fast scanning coherent X-ray imaging using Eiger
The smaller pixel size, high frame rate, and high dynamic range of next-generation photon counting pixel detectors expedites measurements based on coherent diffractive imaging (CDI). The latter comprises methods that exploit the coherence of X-ray synchrotron sources to replace imaging optics by reconstruction algorithms. Researchers from the Paul Scherrer Institut have recently demonstrated fast CDI image acquisition above 25,000 resolution elements per second using an in-house developed Eiger detector. This rate is state of the art for diffractive imaging and even on a par with the fastest scanning X-ray transmission instruments. High image throughput is of crucial importance for both materials and biological sciences for studies with representative population sampling.
X-ray tomography reaches 16 nm isotropic 3D resolution
Researchers at PSI reported a demonstration of X-ray tomography with an unmatched isotropic 3D resolution of 16 nm in Scientific Reports. The measurement was performed at the cSAXS beamline at the Swiss Light Source using a prototype instrument of the OMNY (tOMography Nano crYo) project. Whereas this prototype measures at room temperature and atmospheric pressure, the OMNY system, to be commissioned later this year, will provide a cryogenic sample environment in ultra-high vacuum without compromising imaging capabilities. The researchers believe that such a combination of advanced imaging with state-of-the-art instrumentation is a promising path to fill the resolution gap between electron microscopy and X-ray imaging, also in case of radiation-sensitive materials such as polymer structures and biological systems.
Unique insight into carbon fibers on the nanoscale
The investigation of the mechanical properties of carbon fibers benefits from highly resolved three-dimensional density maps within representative volumes, but such images are not easily obtained with standard methods. Scientists from the Paul Scherrer Institut in collaboration with Honda R&D in Germany have recently visualized density distributions on the sub-micrometer scale within entire carbon fiber sections, revealing surprising graphite distributions within the fibers. This capability will prove useful for the systematic characterization of fibers, contributing to the development of light and robust materials at lower costs.
X-ray Laser: A novel tool for structural studies of nano-particles
Prominent among the planned applications of X-ray free electron laser facilities, such as the future SwissFEL at the Paul Scherrer Institute, PSI, are structural studies of complex nano-particles, down to the scale of individual bio-molecules. A major challenge for such investigations is the mathematical reconstruction of the particle form from the measured scattering data. Researchers at PSI have now demonstrated an optimized mathematical procedure for treating such data, which yields a dramatically improved single-particle structural resolution. The procedure was successfully tested at the Swiss Light Source synchrotron at PSI.
Imaging fluctuations with X-ray microscopy
X-rays are used to investigate nanoscale structures of objects as varied as single cells or magnetic storage media. Yet, high-resolution images impose extreme constraints on both the X ray microscope and the samples under investigation. Researchers at the Technische Universität München the PSI now showed how to relax these conditions without loss of image quality. They further showed how to image objects featuring fast fluctuations, such as the rapid switching events that determine the life time of data storage in magnetic materials.
Nanoforscher untersuchen Karies
Forscher der Universität Basel und des Paul Scherrer Instituts konnten im Nanomassstab zeigen, wie sich Karies auf die menschlichen Zähne auswirkt. Ihre Studie eröffnet neue Perspektiven für die Behandlung von Zahnschäden, bei denen heute nur der Griff zum Bohrer bleibt. Die Forschungsergebnisse wurden in der Fachzeitschrift «Nanomedicine» veröffentlicht.This news release is only available in German.
X-ray methods help to understand brain disorders better
An international team of researchers has developed a new method for making detailed X-ray images of brain tissue, which has been used to make the myelin sheaths of nerve fibres visible. Damage to these protective sheaths can lead to various disorders, such as multiple sclerosis. The facility for creating these images of the protective sheaths of nerve cells is being operated at the Swiss Light Source (SLS), at the Paul Scherrer Institute.
High-resolution method for computed nano-tomography developed
High-resolution method for computed nano-tomography developedA novel nano-tomography method developed by a team of researchers from the Technische Universität München, the Paul Scherrer Institute and the ETH Zurich opens the door to computed tomography examinations of minute structures at nanometer resolutions. The new method makes possible, for example, three-dimensional internal imaging of fragile bone structures.