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Laboratory of Biomolecular Research (LBR)

The Laboratory of Biomolecular Research (LBR) works on three broad, overlapping research topics:
  1. membrane protein structure and function,
  2. structure-function relationships of macromolecular assemblies of the cell and
  3. new methods for bio-structural analysis.
The Principal Investigators at the LBR have academic freedom in achieving the scientific goals of their projects. The LBR is responsible for key research facilities at PSI: electron microscopy, biophysics and light microscopy, protein production; with SLS, the LBR shares responsibility for the protein crystallisation facility . The LBR Young Researchers Network (LYRN) organises scientific and social activities to complement LBR’s excellent research infrastructure, providing an attractive environment for young scientists in structural biology.

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News



FreeNovation Grants 2017

LBR received three FreeNovation grants. These Novartis grants support unconventional ideas with a strong potential for a high impact in medicine.

Topics / PI's:

Scaffolds for the structure elucidation of GPCR-drug complexes from single particles by cryo-EM - Roger Benoit

Deep signaling - Bridging the gap between drug discovery and clinic - Tilman Flock, Xavier Deupi, Dmitry Veprintsev

Towards the structure based design of broad-spectrum antiapicomplexan drugs - Michel Steinmetz, Natacha Olieric, Aswani Sharma