The Laboratory of Biomolecular Research (LBR) works on three broad, overlapping research topics:
membrane protein structure and function,
structure-function relationships of macromolecular assemblies of the cell and
new methods for bio-structural analysis.
The Principal Investigators at the LBR have academic freedom in achieving the scientific goals of their projects. The LBR is responsible for key research facilities at PSI: electron microscopy, biophysics and light microscopy, protein production; with SLS, the LBR shares responsibility for the protein crystallisation facility . The LBR Young Researchers Network (LYRN) organises scientific and social activities to complement LBR’s excellent research infrastructure, providing an attractive environment for young scientists in structural biology.
FreeNovation Grants 2017
LBR received three FreeNovation grants. These Novartis grants support unconventional ideas with a strong potential for a high impact in medicine.
Topics / PI's:
Scaffolds for the structure elucidation of GPCR-drug complexes from single particles by cryo-EM - Roger Benoit
Deep signaling - Bridging the gap between drug discovery and clinic - Tilman Flock, Xavier Deupi, Dmitry Veprintsev
Towards the structure based design of broad-spectrum antiapicomplexan drugs - Michel Steinmetz, Natacha Olieric, Aswani Sharma