Lab News & Scientific Highlights
Biased signalling for better drugs
A dream drug would provide a targeted therapeutic effect without side effects. Biased signalling could make this a reality. Publishing in PNAS, PSI researchers present a platform for biased signalling-based drug discovery.
Fingerprint of Copper in Peptides Linked to Alzheimer's Disease
In an interdisciplinary project, researchers from the Laboratory of Nanoscale Biology in BIO and the Laboratory for Condensed Matter in PSD have revealed the reaction between the nitrogen atoms of the amyloid-beta peptide and copper/zinc ions by using soft X-ray absorption spectroscopy.
Effective combination cancer treatment
Combining two chemotherapeutic drugs inhibits tumour growth.
EANM Marie-Curie Award 2021 went to VIVIANE TSCHAN
Viviane Tschan received this year’s Marie-Curie Award for a new concept of radioligand therapy of prostate cancer.
Protein distancing
PSI researchers have developed a new method to attach proteins to the surface of virus-like particles.
A strong commitment for science communication
PSI is engaging in public outreach at a major event in Zürich, the "Scientifica" Science Days September 4 and 5.
Prof. Dr. Roger Schibli has been elected a Council Member 2020-2022 of the European Society for Molecular Imaging - ESMI
European Society for Molecular Imaging - ESMI
The ESMI represents and advocates IMAGING SCIENCE
The ESMI is providing an international, interdisciplinary platform for knowledge exchange in the field covering basic sciences, translational aspects as well as clinical applications.
Catching Alzheimer's Toxin
Single-particle cryo-electron microscopy of a functional Aβ42 pore equivalent, created by fusing Aβ42 to the oligomerizing, soluble domain of the α-hemolysin toxin, offers new insights into structure and function of proteins forming amyloid aggregates in Alzheimer’s disease.
Cell cytoskeleton as target for new active agents
Using a combination of computer simulations and laboratory experiments, PSI researchers have identified new binding sites for active agents on the vital protein tubulin.