Publications

2017

  • Evaluation of [11C]Me-NB1 as a potential PET radioligand for measuring GluN2B-containing NMDA receptors, drug occupancy and receptor crosstalk Krämer SD, Betzel T, Mu L, Haider A, Herde Müller A, Boninsegni AK, Keller C1, Szermerski M, Schibli R, Wünsch B, Ametamey SM
    JOURNAL OF NUCLEAR MEDICINE , (2017).
    DOI: jnumed.117.200451
  • Metabotropic glutamate receptor 5 binding in male patients with alcohol use disorder Akkus F, Mihov Y, Treyer V, Ametamey SM, Johayem A, Senn S, Rösner S, Buck A, Hasler G
    TRANSLATIONAL PSYCHIATRY 8, 17 (2017).
    DOI: s41398-017-0066-6
  • Imaging the glutamate receptor subtypes-Much achieved, and still much to do Gruber S, Ametamey SM
    DRUG DISCOVERY TODAY: TECHNOLOGIES 25, 27 (2017).
    DOI: j.ddtec.2017.10.006
  • A first-in-man PET study of [18F]PSS232, a fluorinated ABP688 derivative for imaging metabotropic glutamate receptor subtype 5 Warnock G, Sommerauer M, Mu L, Pla Gonzalez G, Geistlich S, Treyer V, Schibli R, Buck A, Krämer SD, Ametamey SM
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING , (2017).
    DOI: s00259-017-3879-x
  • Radioligands for positron emission tomography imaging of cannabinoid type 2 receptor Spinelli F, Mu L, Ametamey SM
    JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS , (2017).
    DOI: jlcr.3579
  • Cerebral mGluR5 availability contributes to elevated sleep need and behavioral adjustment after sleep deprivation Holst SC, Sousek A, Hefti K, Saberi-Moghadam S, Buck A, Ametamey SM, Scheidegger M, Franken P, Henning A, Seifritz E, Tafti M, Landolt HP
    eLIFE , e28751 (2017).
    DOI: eLife.28751
  • Novel peptide probes to assess the tensional state of fibronectin fibers in cancer Arnoldini S, Moscaroli A, Chabria M, Hilbert M, Hertig S, Schibli R, Béhé M, Vogel V
    NATURE COMMUNICATIONS 8, 1793 (2017).
    DOI: s41467-017-01846-0
  • Towards Translational ImmunoPET/MR Imaging of Invasive Pulmonary Aspergillosis: The Humanised Monoclonal Antibody JF5 Detects Aspergillus Lung Infections In Vivo Davies G, Rolle AM, Maurer A, Spycher PR, Schillinger C, Solouk-Saran D, Hasenberg M, Weski J, Fonslet J, Dubois A, Boschetti F, Denat F, Gunzer M, Eichner M, Ryder LS, Jensen M, Schibli R, Pichler BJ, Wiehr S, Thornton CR
    THERANOSTICS 7, 3398 (2017).
    DOI: thno.20919
  • Synthesis, Radiolabeling, and Characterization of Plasma Protein-Binding Ligands: Potential Tools for Modulation of the Pharmacokinetic Properties of (Radio)Pharmaceuticals Müller C, Farkas R, Borgna F, Schmid RM, Benešová M, Schibli R
    BIOCONJUGATE CHEMISTRY 28, 2372 (2017).
    DOI: acs.bioconjchem.7b00378
  • Therapeutic Radiometals Beyond 177Lu and 90Y: Production and Application of Promising α-Particle, β--Particle, and Auger Electron Emitters Müller C, van der Meulen NP, Benešová M, Schibli R
    JOURNAL OF NUCLEAR MEDICINE 58 (Suppl 2), 91S (2017).
    DOI: jnumed.116.186825
  • Clinical evaluation of the radiolanthanide terbium-152: first-in-human PET/CT with 152Tb-DOTATOC Baum RP, Singh A, Benešová M, Vermeulen C, Gnesin S, Köster U, Johnston K, Müller D, Senftleben S, Kulkarni HR, Türler A, Schibli R, Prior JO, van der Meulen NP, Müller C
    DALTON TRANSACTION 46, 14638 (2017).
    DOI: c7dt01936j
  • Folate Receptor-Positive Gynecological Cancer Cells: In Vitro and In Vivo Characterization Siwowska K, Schmid RM, Cohrs S, Schibli R, Müller C
    PHARMACEUTICALS (BASEL) 10, E72 (2017).
    DOI: ph10030072
  • Dual, Site-Specific Modification of Antibodies by Using Solid-Phase Immobilized Microbial Transglutaminase Spycher PR, Amann CA, Wehrmüller JE, Hurwitz DR, Kreis O, Messmer D, Ritler A,3, Küchler A, Blanc A, Béhé M, Walde P, Schibli R
    CHEMBIOCHEM 18, 1923 (2017).
    DOI: cbic.201700188
  • A Short-Term Biological Indicator for Long-Term Kidney Damage after Radionuclide Therapy in Mice Pellegrini G, Siwowska K, Haller S, Antoine DJ, Schibli R, Kipar A, Müller C
    PHARMACEUTICALS (BASEL) 10, E57 (2017).
    DOI: ph10020057
  • First-in-Human PET/CT Imaging of Metastatic Neuroendocrine Neoplasms with Cyclotron-Produced 44Sc-DOTATOC: A Proof-of-Concept Study Singh A,van der Meulen NP, Müller C, Klette I, Kulkarni HR, Türler A, Schibli R, Baum RP
    CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS 32, 124 (2017).
    DOI: cbr.2016.2173
  • Radiolabeled 111In-FGF-2 Is Suitable for In Vitro/Ex Vivo Evaluations and In Vivo Imaging Moscaroli A, Jones G, Lühmann T, Meinel L, Wälti S, Blanc A, Fischer E, Hilbert M, Schibli R, Béhé M
    MOLECULAR PHARMACEUTICS 14, 639 (2017).
    DOI: acs.molpharmaceut.6b0091
  • Automated cGMP-compliant radiosynthesis of [18 F]-(E)-PSS232 for brain PET imaging of metabotropic glutamate receptor subtype 5 Park JY, Son J, Yun M, Ametamey SM, Chun JH
    JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS , (2017).
    DOI: jlcr.3566
  • Human Muscle Precursor Cells Overexpressing PGC-1α Enhance Early Skeletal Muscle Tissue Formation Haralampieva D, Salemi S, Dinulovic I, Sulser T, Ametamey SM, Handschin C, Eberli D
    CELL TRANSPLANTATION 26, 1103 (2017).
    DOI: 096368917X694868
  • Kinetics of lipid bilayer permeation of a series of ionisable drugs and their correlation with human transporter-independent intestinal permeability Hermann KF, Neuhaus CS, Micallef V, Wagner B, Hatibovic M, Aschmann HE, Paech F, Alvarez-Sanchez R, Krämer SD, Belli S
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 104, 150 (2017).
    DOI: j.ejps.2017.03.040
  • GABAA receptor subtypes in the mouse brain: Regional mapping and diazepam receptor occupancy by in vivo [18F]flumazenil PET Müller Herde A, Benke D, Ralvenius WT, Mu L, Schibli R, Zeilhofer HU, Krämer SD
    NEUROIMAGE 15, 279 (2017).
    DOI: j.neuroimage.2017.02.022
  • Cannabinoid receptor type 2 (CB2) as one of the candidate genes in human carotid plaque imaging: Evaluation of the novel radiotracer [11C]RS-016 targeting CB2 in atherosclerosis Meletta R, Slavik R, Mu L, Rancic Z, Borel N, Schibli R, Ametamey SM, Krämer SD, Müller Herde A
    NUCLEAR MEDICINE AND BIOLOGY 47, 31 (2017).
    DOI: j.nucmedbio.2017.01.001
  • 44Sc-PSMA-617 for radiotheragnostics in tandem with 177Lu-PSMA-617-preclinical investigations in comparison with 68Ga-PSMA-11 and 68Ga-PSMA-617 Umbricht CA, Benešová M, Schmid RM, Türler A, Schibli R, van der Meulen NP, Müller C
    EJNMMI RESEARCH 7, 9 (2017).
    DOI: s13550-017-0257-4
  • Metabotropic glutamate receptor 5 neuroimaging in schizophrenia Akkus F, Treyer V, Ametamey SM, Johayem A, Buck A, Hasler G
    SCHIZOPHRENIA RESEARCH 183, 95 (2017).
    DOI: j.schres.2016.11.008
  • Preclinical Comparison of Albumin-Binding Radiofolates: Impact of Linker Entities on the in Vitro and in Vivo Properties Siwowska K, Haller S, Bortoli F, Benešová M, Groehn V, Bernhardt P, Schibli R, Müller C
    MOLECULAR PHARMACEUTICS 14, 523 (2017).
    DOI: acs.molpharmaceut.6b01010
  • Methoxinine - an alternative stable amino acid substitute for oxidation-sensitive methionine in radiolabelled peptide conjugates Grob NM, Behe M, von Guggenberg E, Schibli R, Mindt TL
    JOURNAL OF PEPTIDE SCIENCE 23, 38 (2017).
    DOI: psc.2948
  • Targets and probes for non-invasive imaging of β-cells Jodal A, Schibli R, Béhé M
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 44, 712 (2017).
    DOI: s00259-016-3592-1

2016

  • 44Sc for labeling of DOTA- and NODAGA functionalized peptides: preclinical in vitro and in vivo investigations Domnanich KA, Müller C, Farkas R, Schmid RM, Ponsard B, Schibli S, Türler A, van der Meulen NP
    EJNMMI RADIOPHARMACY AND CHEMISTRY 1, 5 (2016).
    DOI: s41181-016-0013-5
  • Alpha-PET with terbium-149: evidence and perspectives for radiotheragnostics Müller C, Vermeulen C, Köster U, Johnston K, Türler A, Schibli R, van der Meulen NP
    EJNMMI RADIOPHARMACY AND CHEMISTRY 1, 5 (2016).
    DOI: s41181-016-0008-2
  • Preclinical in vivo application of (152)Tb-DOTANOC: a radiolanthanide for PET imaging Müller C, Vermeulen C, Johnston K, Köster U, Schmid R, Türler A, van der Meulen NP
    EJNMMI RESEARCH 6, 35 (2016).
    DOI: s13550-016-0189-4
  • Evaluation of the first 44Sc-labeled Affibody molecule for imaging of HER2-expressing tumors Honarvar H, Müller C, Cohrs S, Haller S, Westerlund K, Karlström AE, van der Meulen NP, Schibli R, Tolmachev V
    NUCLEAR MEDICINE AND BIOLOGY 45, 15 (2016).
    DOI: j.nucmedbio.2016.10.004
  • Production of (28)Mg by bombardment of (nat)Cl with 200MeV protons: Proof-of-concept study for a stacked LiCl target van der Meulen NP, Steyn GF, Vermeulen C, van Rooyen TJ
    APPLIED RADIATION AND ISOTOPES 115, 125 (2016).
    DOI: j.apradiso.2016.04.026
  • Enhanced sensitivity to drugs of abuse and palatable foods following maternal overnutrition Peleg-Raibstein D, Sarker G, Litwan K, Krämer SD, Ametamey SM, Schibli R, Wolfrum C
    TRANSLATIONAL PSYCHIATRY 6, e911 (2016).
    DOI: tp.2016.176
  • Synthesis and Pharmacological Evaluation of [11C]Granisetron and [18F]Fluoropalonosetron as PET Probes for 5-HT3 Receptor Imaging Mu L, Müller Herde A, Rüefli PM, Sladojevich F, Milicevic Sephton S, Krämer SD, Thompson AJ, Schibli R, Ametamey SM, Lochner M
    ACS CHEMICAL NEUROSCIENCE 7, 1552 (2016).
    DOI: acschemneuro.6b00192
  • Synthesis and Biological Evaluation of Thiophene-Based Cannabinoid Receptor Type 2 Radiotracers for PET Imaging Haider A, Müller Herde A, Slavik R, Weber M, Mugnaini C, Ligresti A, Schibli R, Mu L, Mensah Ametamey S
    FRONTIERS IN NEUROSCIENCE 10, 350 (2016).
    DOI: fnins.2016.00350
  • CD80 Is Upregulated in a Mouse Model with Shear Stress-Induced Atherosclerosis and Allows for Evaluating CD80-Targeting PET Tracers Meletta R, Steier L, Borel N, Mu L, Keller C, Chiotellis A, Russo E, Halin C, Ametamey SM, Schibli R, Krämer SD, Müller Herde A
    MOLUCULAR IMAGING and BIOLOGY Epub ahead of print, (2016).
    DOI: s11307-016-0987-0
  • Discovery of a Fluorinated 4-Oxo-Quinoline Derivative as a Potential PET Radiotracer for Imaging CB2 Receptor Slavik R, Müller Herde A, Haider A, Krämer SD, Weber M, Schibli R, Ametamey SM, Mu L
    JOURNAL OF NEUROCHEMISTRY 138, 874 (2016).
    DOI: jnc.13716
  • Inhibition of MNK pathways enhances cancer cell response to chemotherapy with temozolomide and targeted radionuclide therapy Grzmil M, Seebacher J, Hess D, Behe M, Schibli R, Moncayo G, Frank S, Hemmings BA
    CELLULAR SIGNALLING 28, 1412 (2016).
    DOI: j.cellsig.2016.06.005
  • Non-invasive Imaging and Tracking of Engineered Human Muscle Precursor Cells for Skeletal Muscle Tissue Engineering Using Positron Emission Tomography Haralampieva D, Betzel T, Dinulovic I, Salemi S, Stoelting M, Krämer S, Schibli R, Sulser T, Handschin C, Eberli D, Ametamey SM
    JOURNAL OF NUCLEAR MEDICINE Epub ahead of print, (2016).
    DOI:
  • Synthesis, Radiolabeling, and Biological Evaluation of 5-Hydroxy-2-[(18)F]fluoroalkyl-tryptophan Analogues as Potential PET Radiotracers for Tumor Imaging Chiotellis A, Müller Herde A, Rössler SL, Brekalo A1, Gedeonova E, Mu L, Keller C, Schibli R, Krämer SD, Ametamey SM
    JOURNAL OF MEDICINAL CHEMISTRY 59, 5324 (2016).
    DOI: acs.jmedchem.6b00057
  • (64)Cu- and (68)Ga-Based PET Imaging of Folate Receptor-Positive Tumors: Development and Evaluation of an Albumin-Binding NODAGA-Folate Farkas R, Siwowska K, Ametamey SM, Schibli R, van der Meulen NP, Müller C
    MOLECULAR PHARMACEUTICS 13, 1979 (2016).
    DOI: acs.molpharmaceut.6b00143
  • Novel chemoselective (18)F-radiolabeling of thiol-containing biomolecules under mild aqueous conditions Chiotellis A, Sladojevich F, Mu L, Müller Herde A, Valverde IE, Tolmachev V, Schibli R, Ametamey SM, Mindt TL
    CHEMICAL COMMUNICATION 52, 6083 (2016).
    DOI: c6cc01982j
  • Contribution of Auger/conversion electrons to renal side effects after radionuclide therapy: preclinical comparison of (161)Tb-folate and (177)Lu-folate Haller S, Pellegrini G, Vermeulen C, van der Meulen NP, Köster U, Bernhardt P, Schibli R, Müller C
    EJNMMI RESEARCH 1, 13 (2016).
    DOI: s13550-016-0171-1
  • ImmunoPET/MR imaging allows specific detection of Aspergillus fumigatus lung infection in vivo Rolle AM, Hasenberg M, Thornton CR, Solouk-Saran D, Männ L, Weski J, Maurer A, Fischer E, Spycher PR, Schibli R, Boschetti F, Stegemann-Koniszewski S, Bruder D, Severin GW, Autenrieth SE, Krappmann S, Davies G, Pichler BJ, Gunzer M, Wiehr S
    PNAS 113, E1026 (2016).
    DOI: pnas.1518836113
  • Imaging quality of (44)Sc in comparison with five other PET radionuclides using Derenzo phantoms and preclinical PET Bunka M, Müller C, Vermeulen C, Haller S, Türler A, Schibli R, van der Meulen NP
    APPLIED RADIATION AND ISOTOPES 110, 129 (2016).
    DOI: j.apradiso.2016.01.006
  • Preclinical imaging of the co-stimulatory molecules CD80 and CD86 with indium-111-labeled belatacept in atherosclerosis Meletta R, Müller Herde A, Dennler P, Fischer E, Schibli R, Krämer SD
    EJNMMI RESEARCH 6, 1 (2016).
    DOI: s13550-015-0157-4
  • Comparative Studies of Three Pairs of α- and γ-Conjugated Folic Acid Derivatives Labeled with Fluorine-18 Boss SD, Betzel T, Müller C, Fischer CR, Haller S, Reber J, Groehn V, Schibli R, Ametamey SM
    BIOCONJUGATE CHEMISTRY 27, 74 (2016).
    DOI: acs.bioconjchem.5b00644

2015

  • Ex vivo differential phase contrast and magnetic resonance imaging for characterization of human carotid atherosclerotic plaque Meletta R, Borel N, Stolzmann P, Astolfo A, Klohs J, Stampanoni M, Rudin M, Schibli R, Krämer SD, Müller Herde A
    THE INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING 31, 1425 (2015).
    DOI: s10554-015-0706-y
  • Folate receptor-targeted radionuclide therapy: preclinical investigation of anti-tumor effects and potential radionephropathy Haller S, Reber J, Brandt S, Bernhardt P, Groehn V, Schibli R, Müller C
    NUCLEAR MEDICINE AND BIOLOGY 42, 770 (2015).
    DOI: j.nucmedbio.2015.06.006
  • Cyclotron production of (44)Sc: From bench to bedside van der Meulen NP, Bunka M, Domnanich KA, Müller C, Haller S, Vermeulen C, Türler A, Schibli R
    NUCLEAR MEDICINE AND BIOLOGY 42, 745 (2015).
    DOI: j.nucmedbio.2015.05.00
  • Longitudinal in vivo evaluation of bone regeneration by combined measurement of multi-pinhole SPECT and micro-CT for tissue engineering Lienemann PS, Metzger S, Kiveliö AS, Blanc A, Papageorgiou P, Astolfo A, Pinzer BR, Cinelli P, Weber FE, Schibli R, Béhé M, Ehrbar M
    SCIENTIFIC REPORTS 5, 10238 (2015).
    DOI: srep10238 Erratum DOI: srep12391
  • Discovery of a high affinity and selective pyridine analog as a potential positron emission tomography imaging agent for cannabinoid type 2 receptor Slavik R, Grether U, Müller Herde A, Gobbi L, Fingerle J, Ullmer C, Krämer SD, Schibli R, Mu L, Ametamey SM
    JOURNAL OF MEDICINAL CHEMISTRY 58, 4266 (2015).
    DOI: acs.jmedchem.5b00283
  • Evaluation of a Novel Tc-99m Labelled Vitamin B12 Derivative for Targeting Escherichia coli and Staphylococcus aureus In Vitro and in an Experimental Foreign-Body Infection Model Baldoni D, Waibel R, Bläuenstein P, Galli F, Iodice V, Signore A, Schibli R, Trampuz A
    MOLECULAR IMAGING AND BIOLOGY 10, e0123443 (2015).
    DOI: s11307-015-0832-x
  • Evaluation of ¹¹¹in-labelled exendin-4 derivatives containing different meprin β-specific cleavable linkers Jodal A, Pape F, Becker-Pauly C, Maas O, Schibli R, Béhé M
    PLOS ONE 10, e0123443 (2015).
    DOI: journal.pone.0123443
  • Regional cerebral blood flow estimated by early PiB uptake is reduced in mild cognitive impairment and associated with age in an amyloid-dependent manner Gietl AF, Warnock G, Riese F, Kälin AM, Saake A, Gruber E, Leh SE, Unschuld PG, Kuhn FP, Burger C, Mu L, Seifert B, Nitsch RM, Schibli R, Ametamey SM, Buck A, Hock C
    NEUROBIOLOGY OF AGING 36, 1619 (2015).
    DOI: j.neurobiolaging.2014.12.036
  • Microbial transglutaminase and c-myc-tag: a strong couple for the functionalization of antibody-like protein scaffolds from discovery platforms Dennler P, Bailey LK, Spycher PR, Schibli R, Fischer E
    CHEMBIOCHEM 16, 861 (2015).
    DOI: cbic.201500009
  • Dosimetry and first clinical evaluation of the new 18F-radiolabeled bombesin analogue BAY 864367 in patients with prostate cancer Sah BR, Burger IA, Schibli R, Friebe M, Dinkelborg L, Graham K, Borkowski S, Bacher-Stier C, Valencia R, Srinivasan A, Hany TF, Mu L, Wild PJ, Schaefer NG
    JOURNAL OF NUCLEAR MEDICINE 56, 372 (2015).
    DOI: jnumed.114.147116
  • Synthesis and pharmacological evaluation of ¹¹C-labeled piperazine derivative as a PET probe for sigma-2 receptor imaging Selivanova SV, Toscano A, Abate C, Berardi F, Müller A, Krämer SD, Schibli R, Ametamey SM
    NUCLEAR MEDICINE AND BIOLOGY 42, 399 (2015).
    DOI: j.nucmedbio.2014.12.018
  • Evaluation of the radiolabeled boronic acid-based FAP inhibitor MIP-1232 for atherosclerotic plaque imaging Meletta R, Müller Herde A, Chiotellis A, Isa M, Rancic Z, Borel N, Ametamey SM, Krämer SD, Schibli R
    MOLUCULES 20, 2081 (2015).
    DOI: molecules20022081
  • Investigation of the chick embryo as a potential alternative to the mouse for evaluation of radiopharmaceuticals Haller S, Ametamey SM, Schibli R, Müller C
    NUCLEAR MEDICINE AND BIOLOGY 42, 226 (2015).
    DOI: j.nucmedbio.2014.10.010
  • Quantitative positron emission tomography of mGluR5 in rat brain with [(18) F]PSS232 at minimal invasiveness and reduced model complexity Müller Herde A, Keller C, Milicevic Sephton S, Mu L, Schibli R, Ametamey SM, Krämer SD
    JOURNAL OF NEUROCHEMISTRY 133, 330 (2015).
    DOI: jnc.13001
  • Site-Specific Conjugation of Monomethyl Auristatin E to Anti-CD30 Antibodies Improves Their Pharmacokinetics and Therapeutic Index in Rodent Models Lhospice F, Delphine B, Belmant C, Patrick D, Aristeidis C, Fischer E, Laurent G, Bonnafous C, Viaud N, Represa A, Boëdec A, Rispaud Blanc H, Sapet M, Delcambre C, Ingoure S, Savard Chambard S, Schneider N, Paturel C, Schibli R, Romagne F
    MOLECULAR PHARMACEUTICS 12, 1863 (2015).
    DOI: mp500666j
  • Association of Long-Term Nicotine Abstinence with Normal Metabotropic Glutamate Receptor-5 Binding Akkus F, Treyer V, Johayem A, Ametamey SM, Mancilla BG, Sovago J, Buck A, Hasler G
    BIOLOGYCAL PSYCHATRY , (2015).
    DOI: 10.1016/j.biopsych.2015.02.027
  • Synthesis, radiolabeling and evaluation of novel 4-oxo-quinoline derivatives as PET tracers for imaging cannabinoid type 2 receptor Slavik R, Herde AM1, Bieri D, Weber M, Schibli R, Krämer SD, Ametamey SM, Mu L
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 92, 554 (2015).
    DOI: j.ejmech.2015.01.028
  • Folate Receptor-Targeted Multimodality Imaging of Ovarian Cancer in a Novel Syngeneic Mouse Model Ocak M, Gillman AG, Bresee J, Zhang L, Vlad AM, Müller C, Schibli R, Edwards WB, Anderson CJ, Gach HM
    MOLECULAR PHARMACEUTICS 12, 542 (2015).
    DOI: mp500628g
  • Self-assembled gold coating enhances X-ray imaging of alginate microcapsules Qie F, Astolfo A, Wickramaratna M, Behe M, Evans MD, Hughes TC, Hao X, Tan T
    NANOSCALE 7, 2480 (2015).
    DOI: c4nr06692h
  • Excitation functions of natZr + p nuclear processes up to 70 MeV: New measurements and compilation Szelecsényi F, Steyn GF, Kovács Z, Vermeulen C, Nagatsu K, Zhang MR, Suzuki K
    NUCLEAR INSTRUMENTS AND METHODS IN PHYSICS RESEARCH B 343, 173 (2015).
    DOI: j.nimb.2014.11.081
  • Preclinical evaluation and test-retest studies of [(18)F]PSS232, a novel radioligand for targeting metabotropic glutamate receptor 5 (mGlu5) Sephton SM, Herde AM, Mu L, Keller C, Rüdisühli S, Auberson Y, Schibli R, Krämer SD, Ametamey SM
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 42, 128 (2015).
    DOI: s00259-014-2883-7

2014

  • EANM guideline for the preparation of an Investigational Medicinal Product Dossier (IMPD) Todde S, Windhorst AD, Behe M, Bormans G, Decristoforo C, Faivre-Chauvet A, Ferrari V, Gee AD, Gulyas B, Halldin C, Peitl PK, Koziorowski J, Mindt TL, Sollini M, Vercouillie J, Ballinger JR, Elsinga PH
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 41, 2175 (2014).
    DOI: s00259-014-2866-8
  • Guidance on current good radiopharmacy practice for the small-scale preparation of radiopharmaceuticals using automated modules: a European perspective Aerts J, Ballinger JR, Behe M, Decristoforo C, Elsinga PH, Faivre-Chauvet A, Mindt TL, Kolenc Peitl P, Todde SC, Koziorowski J
    JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS 57, 615 (2014).
    DOI: jlcr.3227
  • Investigation of the chick embryo as a potential alternative to the mouse for evaluation of radiopharmaceuticals Haller S, Ametamey SM, Schibli R, Müller C
    NUCLEAR MEDICINE AND BIOLOGY , (2014).
    DOI: j.nucmedbio.2014.10.010
  • Quantitative positron emission tomography (PET) of mGluR5 in rat brain with [18 F]PSS232 at minimal invasiveness and reduced model complexity Müller Herde A, Keller C, Milicevic Sephton S, Mu L, Schibli R, Ametamey SM, Krämer SD
    JOURNAL OF NEUROCHEMISTRY , (2014).
    DOI: jnc.13001
  • Metabotropic glutamate receptor 5 binding in patients with obsessive-compulsive disorder Akkus F, Terbeck S, Ametamey SM, Rufer M, Treyer V, Burger C, Johayem A, Mancilla BG, Sovago J, Buck A, Hasler G
    THE INTERNATIONAL JOURNAL OF NEUROPHARMACOLOGY 17, 1915 (2014).
    DOI: S1461145714000716
  • Cell-Free Microfluidic Determination of P-glycoprotein Interactions with Substrates and Inhibitors Eyer K, Herger M, Krämer SD, Dittrich PS
    PHARMACEUTICAL RESEARCH 31, 3415 (2014).
    DOI: s11095-014-1431-2
  • Paclitaxel improved anti-L1CAM lutetium-177 radioimmunotherapy in an ovarian cancer xenograft model Lindenblatt D, Fischer E, Cohrs S, Schibli R, Grünberg J
    EJNMMI RESEARCH 4;1, 54 (2014).
    DOI: s13550-014-0054-2
  • In vitro and in vivo evaluation of N-{2-[4-(3-Cyanopyridin-2-yl)piperazin-1-yl]ethyl}-3-[(11) C]methoxybenz-amide, a positron emission tomography (PET) radioligand for dopamine D4 receptors, in rodents Leopoldo M, Selivanova SV, Müller A, Lacivita E, Schetz JA, Ametamey SM
    CHEMISTRY & BIODIVERSITY 11, 1298 (2014).
    DOI: cbdv.201400178
  • First Clinical Results of (d)-18F-Fluoromethyltyrosine (BAY 86-9596) PET/CT in Patients with Non-Small Cell Lung Cancer and Head and Neck Squamous Cell Carcinoma Burger IA, Zitzmann-Kolbe S, Pruim J, Friebe M, Graham K, Stephens A, Dinkelborg L, Kowal K, Schibli R, Luurtsema G, Maas B, Horn-Tutic M, Haerle SK, Wiegers J, Schaefer NG, Hany TF, von Schulthess GK
    JOURNAL OF NUCLEAR MEDICINE 55, 330 (2014).
    DOI: jnumed.114.140699
  • Promising Prospects for 44Sc-/47Sc-Based Theragnostics: Application of 47Sc for Radionuclide Tumor Therapy in Mice Müller C, Bunka M, Haller S, Köster U, Groehn V, Bernhardt P, van der Meulen N, Türler A, Schibli R
    JOURNAL OF NUCLEAR MEDICINE 55, 1658 (2014).
    DOI: jnumed.114.141614
  • A comparison of three (67/68)Ga-labelled exendin-4 derivatives for β-cell imaging on the GLP-1 receptor: the influence of the conjugation site of NODAGA as chelator Jodal A, Lankat-Buttgereit B, Brom M, Schibli R, Béhé M
    EJNMMI RESEARCH 22;4, 31 (2014).
    DOI: s13550-014-0031-9
  • Synthesis and Biological Evaluation of 18F-Labeled Fluoroethoxy Tryptophan Analogues as Potential PET Tumor Imaging Agents Chiotellis A, Müller A, Mu L, Keller C, Schibli R, Krämer SD, Ametamey SM
    MOLECULAR PHARMACEUTICS , (2014).
    DOI: mp500312t
  • Development and evaluation of novel PET tracers for imaging cannabinoid receptor type 2 in brain Slavik R, Bieri D, Cermak S, Müller A, Krämer SD, Weber M, Schibli R, Ametamey SM, Mu L
    CHIMIA (AARAU) 68, 208 (2014).
    DOI: chimia.2014.208
  • Anti-L1CAM radioimmunotherapy is more effective with the radiolanthanide terbium-161 compared to lutetium-177 in an ovarian cancer model Grünberg J, Lindenblatt D, Dorrer H, Cohrs S, Zhernosekov K, Köster U, Türler A, Fischer E, Schibli R
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 41, 1907 (2014).
    DOI: s00259-014-2798-3
  • Gene expression levels of matrix metalloproteinases in human atherosclerotic plaques and evaluation of radiolabeled inhibitors as imaging agents for plaque vulnerability Müller A, Krämer SD, Meletta R, Beck K, Selivanova SV, Rancic Z, Kaufmann PA, Vos B, Meding J, Stellfeld T, Heinrich TK, Bauser M, Hütter J, Dinkelborg LM, Schibli R, Ametamey SM
    NUCLEAR MEDICINE AND BIOLOGY 41, 562 (2014).
    DOI: j.nucmedbio.2014.04.085
  • Towards non-invasive imaging of vulnerable atherosclerotic plaques by targeting co-stimulatory molecules Müller A, Mu L, Meletta R, Beck K, Rancic Z, Drandarov K, Kaufmann PA, Ametamey SM, Schibli R, Borel N, Krämer SD
    INTERNATIONAL JOURNAL OF CARDIOLOGY 174, 503 (2014).
    DOI: j.ijcard.2014.04.071
  • Synthesis and preliminary biological evaluation of O-2((2-[(18)F]fluoroethyl)methylamino)ethyltyrosine ([ (18)F]FEMAET) as a potential cationic amino acid PET tracer for tumor imaging Chiotellis A, Müller A, Weyermann K, Leutwiler DS, Schibli R, Ametamey SM, Krämer SD, Mu L
    AMINO ACIDS 46, 1947 (2014).
    DOI: s00726-014-1754-7
  • Delivery of BMP-2 by two clinically available apatite materials: In vitro and in vivo comparison Hänseler P, Ehrbar M, Kruse A, Fischer E, Schibli R, Ghayor C, Weber FE
    JOURNAL OF BIOMEDICAL MATERIAL RESEARCH , (2014).
    DOI: jbm.a.35211
  • Synthesis and Preliminary Evaluation of a 2-Oxoquinoline Carboxylic Acid Derivative for PET Imaging the Cannabinoid Type 2 Receptor Mu L, Slavik R, Müller A, Popaj K, Cermak S, Weber M, Schibli R, Krämer SD, Ametamey SM
    PHARMACEUTICALS (BASEL) 7, 339 (2014).
    DOI: ph7030339
  • Folate receptor targeted alpha-therapy using terbium-149 Müller C, Reber J, Haller S, Dorrer H, Köster U, Johnston K, Zhernosekov K, Türler A, Schibli R
    PHARMACEUTICALS (BASEL) 7, 353 (2014).
    DOI: ph7030353
  • Imaging Atherosclerotic Plaque Inflammation via Folate Receptor Targeting Using a Novel 18F-Folate Radiotracer Müller A, Beck K, Rancic Z, Müller C, Fischer CR, Betzel T, Kaufmann PA, Schibli R, Krämer SD, Ametamey SM
    MOLECULAR IMAGING 13, 1 (2014).
    DOI:
  • Noninvasive positron emission tomography and fluorescence imaging of CD133+ tumor stem cells Gaedicke S, Braun F, Prasad S, Machein M, Firat E, Hettich M, Gudihal R, Zhu X, Klingner K, Schüler J, Herold-Mende CC, Grosu AL, Behe M, Weber W, Mäcke H, Niedermann G
    PNAS 111, E692 (2014).
    DOI: pnas.1314189111
  • Transglutaminase-Based Chemo-Enzymatic Conjugation Approach Yields Homogeneous Antibody-Drug Conjugates Dennler P, Chiotellis A, Fischer E, Brégeon D, Belmant C, Gauthier L, Lhospice F, Romagne F, Schibli R
    BIOCONJUGATE CHEMISTRY 25, 569 (2014).
    DOI: bc400574z
  • Tumor Imaging in Patients with Advanced Tumors Using a New 99mTc-Radiolabeled Vitamin B12 Derivative Sah BR, Schibli R, Waibel R, von Boehmer L, Bläuenstein P, Nexo E, Johayem A, Fischer E, Müller E, Soyka JD, Knuth AK, Haerle SK, Schubiger PA, Schaefer NG, Burger IA
    THE JOURNAL OF NUCLEAR MEDICINE 55, 43 (2014).
    DOI: jnumed.113.122499
  • MRS glucose mapping and PET joining forces: Re-evaluation of the lumped constant in the rat brain under isoflurane anaesthesia Alf MF, Duarte JM, Lei H, Krämer SD, Mlynarik V, Schibli R, Gruetter R
    THE JOURNAL OF NEURUCHEMISTRY , (2014).
    DOI: jnc.12667
  • Future prospects for SPECT imaging using the radiolanthanide terbium-155 - production and preclinical evaluation in tumor-bearing mice Müller C, Fischer E, Behe M, Köster U, Dorrer H, Reber J, Haller S, Cohrs S, Blanc A, Grünberg J, Bunka M, Zhernosekov K, van der Meulen N, Johnston K, Türler A, Schibli R
    NUCLEAR MEDICINE AND BIOLOGY 41, Suppl:e58 (2014).
    DOI: j.nucmedbio.2013.11.002