Publications
2021
2020
2019
2018
- Visualisation of interstitial lung disease by molecular imaging of integrin αvβ3 and somatostatin receptor 2
ANNALS OF THE RHEUMATIC DISEASES , (2018).DOI: annrheumdis-2018-214322
- Design and Preclinical Evaluation of an Albumin-Binding PSMA Ligand for 64Cu-Based PET Imaging
MOLECULAR PHARMACEUTICS , (2018).DOI: acs.molpharmaceut.8b00712
- Metabotropic glutamate receptor subtype 5 is altered in LPS-induced murine neuroinflammation model and in the brains of AD and ALS patients
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING , (2018).DOI: s00259-018-4179-9
- In Vivo Labeling of Plasma Proteins for Imaging of Enhanced Vascular Permeability in the Lungs
MOLECULAR PHARMACEUTICS 15, 4995 (2018).DOI: acs.molpharmaceut.8b00606
- Combination of lutetium-177 labelled anti-L1CAM antibody chCE7 with the clinically relevant protein kinase inhibitor MK1775: a novel combination against human ovarian carcinoma
BMC CANCER 18, 922 (2018).DOI: s12885-018-4836-1
- Ketamine and Ceftriaxone-Induced Alterations in Glutamate Levels Do Not Impact the Specific Binding of Metabotropic Glutamate Receptor Subtype 5 Radioligand [18F]PSS232 in the Rat Brain
PHARMACEUTICASL (BASEL) E83, (2018).DOI: ph11030083
- Evaluation of 99mTc-rhAnnexin V-128 SPECT/CT as a diagnostic tool for early stages of interstitial lung disease associated with systemic sclerosis
ATHRITIS RESEARCH AND THERAPY 20, 183 (2018).DOI: s13075-018-1681-1
- Identification and Preclinical Evaluation of a Radiofluorinated Benzazepine Derivative for Imaging the GluN2B Subunit of the Ionotropic NMDA Receptor
JOURNAL OF NUCLEAR MEDICINE , (2018).DOI: jnumed.118.212134
- Physiologically Based Pharmacokinetic Modelling with Dynamic PET Data to Study the In Vivo Effects of Transporter Inhibition on Hepatobiliary Clearance in Mice
CONTRAST MEDIA AND MOLECULAR IMAGING 5849047, (2018).DOI: 5849047
- Unexpected reactivity of cyclic perfluorinated iodanes with electrophiles
CHEMICAL COMMUNICATIONS 54, 8999 (2018).DOI: c8cc04558e
- Diastereomerically Pure 6R- and 6S-3'-aza-2'-18F-Fluoro-5-Methyltetrahydrofolates Show Unprecedented High Uptake in Folate Receptor-positive KB Tumors
JOURNAL OF NUCLEAR MEDICINE , (2018).DOI: jnumed.118.213314
- Pharmacological upregulation of prostate-specific membrane antigen (PSMA) expression in prostate cancer cells
PROSTATE 78, 758 (2018).DOI: pros.23522
- Combining Albumin-Binding Properties and Interaction with Pemetrexed to Improve the Tissue Distribution of Radiofolates
MOLECULES 23, E1465 (2018).DOI: molecules23061465
- Scandium and terbium radionuclides for radiotheranostics: current state of development towards clinical application
BRITISH JOURNAL OF RADIOLOGY , (2018).DOI: bjr.20180074
- Preclinical Development of Novel PSMA-Targeting Radioligands: Modulation of Albumin-Binding Properties To Improve Prostate Cancer Therapy
MOLECULAR PHARMACEUTICALS , (2018).DOI: acs.molpharmaceut.8b00152
- Injected Human Muscle Precursor Cells Overexpressing PGC-1α Enhance Functional Muscle Regeneration after Trauma
STEM CELL INTERNATIONAL 2018, 465850 (2018).DOI: 4658503
- Radiosynthesis and evaluation of an 18F-labeled silicon containing exendin-4 peptide as a PET probe for imaging insulinoma
EJNMMI RADIOPHARMACY AND CHEMISTRY 3, 1 (2018).DOI: s41181-017-0036-6
- Improved Syntheses of the Mglu₅ Antagonists MMPEP and MTEP Using Sonogashira Cross-Coupling
PHARMACEUTICALS (BASEL) 11, E24 (2018).DOI: ph11010024
- Evaluation of 4-oxo-quinoline-based CB2 PET radioligands in R6/2 chorea huntington mouse model and human ALS spinal cord tissue
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 145, 746 (2018).DOI: j.ejmech.2017.12.097
- Evaluation of 11C-Me-NB1 as a Potential PET Radioligand for Measuring GluN2B-Containing NMDA Receptors, Drug Occupancy, and Receptor Cross Talk
JOURNAL OF NUCLEAR MEDICINE 59, 698 (2018).DOI: jnumed.117.200451
- A first-in-man PET study of [18F]PSS232, a fluorinated ABP688 derivative for imaging metabotropic glutamate receptor subtype 5
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 45, 1041 (2018).DOI: s00259-017-3879-x
- Imaging of Folate Receptor Expressing Macrophages in the Rat Groove Model of Osteoarthritis: Using a New DOTA-Folate Conjugate
CARTILAGE 9, 183 (2018).DOI: 1947603517738073
- Albumin-Binding PSMA Ligands: Optimization of the Tissue Distribution Profile
MOLECULAR PHARMACEUTICS 15, 934 (2018).DOI: acs.molpharmaceut.7b00877
- Reduced 18F-Folate Conjugates as a New Class of PET Tracers for Folate Receptor Imaging
BIOCONJUGATE CHEMISTRY 29, 1119 (2018).DOI: acs.bioconjchem.7b00775
2017
- Metabotropic glutamate receptor 5 binding in male patients with alcohol use disorder
TRANSLATIONAL PSYCHIATRY 8, 17 (2017).DOI: s41398-017-0066-6
- Imaging the glutamate receptor subtypes-Much achieved, and still much to do
DRUG DISCOVERY TODAY: TECHNOLOGIES 25, 27 (2017).DOI: j.ddtec.2017.10.006
- Radioligands for positron emission tomography imaging of cannabinoid type 2 receptor
JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS , (2017).DOI: jlcr.3579
- Cerebral mGluR5 availability contributes to elevated sleep need and behavioral adjustment after sleep deprivation
eLIFE , e28751 (2017).DOI: eLife.28751
- Novel peptide probes to assess the tensional state of fibronectin fibers in cancer
NATURE COMMUNICATIONS 8, 1793 (2017).DOI: s41467-017-01846-0
- Towards Translational ImmunoPET/MR Imaging of Invasive Pulmonary Aspergillosis: The Humanised Monoclonal Antibody JF5 Detects Aspergillus Lung Infections In Vivo
THERANOSTICS 7, 3398 (2017).DOI: thno.20919
- Synthesis, Radiolabeling, and Characterization of Plasma Protein-Binding Ligands: Potential Tools for Modulation of the Pharmacokinetic Properties of (Radio)Pharmaceuticals
BIOCONJUGATE CHEMISTRY 28, 2372 (2017).DOI: acs.bioconjchem.7b00378
- Therapeutic Radiometals Beyond 177Lu and 90Y: Production and Application of Promising α-Particle, β--Particle, and Auger Electron Emitters
JOURNAL OF NUCLEAR MEDICINE 58 (Suppl 2), 91S (2017).DOI: jnumed.116.186825
- Clinical evaluation of the radiolanthanide terbium-152: first-in-human PET/CT with 152Tb-DOTATOC
DALTON TRANSACTION 46, 14638 (2017).DOI: c7dt01936j
- Folate Receptor-Positive Gynecological Cancer Cells: In Vitro and In Vivo Characterization
PHARMACEUTICALS (BASEL) 10, E72 (2017).DOI: ph10030072
- Dual, Site-Specific Modification of Antibodies by Using Solid-Phase Immobilized Microbial Transglutaminase
CHEMBIOCHEM 18, 1923 (2017).DOI: cbic.201700188
- A Short-Term Biological Indicator for Long-Term Kidney Damage after Radionuclide Therapy in Mice
PHARMACEUTICALS (BASEL) 10, E57 (2017).DOI: ph10020057
- First-in-Human PET/CT Imaging of Metastatic Neuroendocrine Neoplasms with Cyclotron-Produced 44Sc-DOTATOC: A Proof-of-Concept Study
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS 32, 124 (2017).DOI: cbr.2016.2173
- Radiolabeled 111In-FGF-2 Is Suitable for In Vitro/Ex Vivo Evaluations and In Vivo Imaging
MOLECULAR PHARMACEUTICS 14, 639 (2017).DOI: acs.molpharmaceut.6b0091
- Automated cGMP-compliant radiosynthesis of [18 F]-(E)-PSS232 for brain PET imaging of metabotropic glutamate receptor subtype 5
JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS , (2017).DOI: jlcr.3566
- Human Muscle Precursor Cells Overexpressing PGC-1α Enhance Early Skeletal Muscle Tissue Formation
CELL TRANSPLANTATION 26, 1103 (2017).DOI: 096368917X694868
- Kinetics of lipid bilayer permeation of a series of ionisable drugs and their correlation with human transporter-independent intestinal permeability
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 104, 150 (2017).DOI: j.ejps.2017.03.040
- GABAA receptor subtypes in the mouse brain: Regional mapping and diazepam receptor occupancy by in vivo [18F]flumazenil PET
NEUROIMAGE 15, 279 (2017).DOI: j.neuroimage.2017.02.022
- Cannabinoid receptor type 2 (CB2) as one of the candidate genes in human carotid plaque imaging: Evaluation of the novel radiotracer [11C]RS-016 targeting CB2 in atherosclerosis
NUCLEAR MEDICINE AND BIOLOGY 47, 31 (2017).DOI: j.nucmedbio.2017.01.001
- 44Sc-PSMA-617 for radiotheragnostics in tandem with 177Lu-PSMA-617-preclinical investigations in comparison with 68Ga-PSMA-11 and 68Ga-PSMA-617
EJNMMI RESEARCH 7, 9 (2017).DOI: s13550-017-0257-4
- Metabotropic glutamate receptor 5 neuroimaging in schizophrenia
SCHIZOPHRENIA RESEARCH 183, 95 (2017).DOI: j.schres.2016.11.008
- Preclinical Comparison of Albumin-Binding Radiofolates: Impact of Linker Entities on the in Vitro and in Vivo Properties
MOLECULAR PHARMACEUTICS 14, 523 (2017).DOI: acs.molpharmaceut.6b01010
- Methoxinine - an alternative stable amino acid substitute for oxidation-sensitive methionine in radiolabelled peptide conjugates
JOURNAL OF PEPTIDE SCIENCE 23, 38 (2017).DOI: psc.2948
- Targets and probes for non-invasive imaging of β-cells
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 44, 712 (2017).DOI: s00259-016-3592-1
2016
- 44Sc for labeling of DOTA- and NODAGA functionalized peptides: preclinical in vitro and in vivo investigations
EJNMMI RADIOPHARMACY AND CHEMISTRY 1, 5 (2016).DOI: s41181-016-0013-5
- Alpha-PET with terbium-149: evidence and perspectives for radiotheragnostics
EJNMMI RADIOPHARMACY AND CHEMISTRY 1, 5 (2016).DOI: s41181-016-0008-2
- Preclinical in vivo application of (152)Tb-DOTANOC: a radiolanthanide for PET imaging
EJNMMI RESEARCH 6, 35 (2016).DOI: s13550-016-0189-4
- Evaluation of the first 44Sc-labeled Affibody molecule for imaging of HER2-expressing tumors
NUCLEAR MEDICINE AND BIOLOGY 45, 15 (2016).DOI: j.nucmedbio.2016.10.004
- Production of (28)Mg by bombardment of (nat)Cl with 200MeV protons: Proof-of-concept study for a stacked LiCl target
APPLIED RADIATION AND ISOTOPES 115, 125 (2016).DOI: j.apradiso.2016.04.026
- Enhanced sensitivity to drugs of abuse and palatable foods following maternal overnutrition
TRANSLATIONAL PSYCHIATRY 6, e911 (2016).DOI: tp.2016.176
- Synthesis and Pharmacological Evaluation of [11C]Granisetron and [18F]Fluoropalonosetron as PET Probes for 5-HT3 Receptor Imaging
ACS CHEMICAL NEUROSCIENCE 7, 1552 (2016).DOI: acschemneuro.6b00192
- Synthesis and Biological Evaluation of Thiophene-Based Cannabinoid Receptor Type 2 Radiotracers for PET Imaging
FRONTIERS IN NEUROSCIENCE 10, 350 (2016).DOI: fnins.2016.00350
- CD80 Is Upregulated in a Mouse Model with Shear Stress-Induced Atherosclerosis and Allows for Evaluating CD80-Targeting PET Tracers
MOLUCULAR IMAGING and BIOLOGY Epub ahead of print, (2016).DOI: s11307-016-0987-0
- Discovery of a Fluorinated 4-Oxo-Quinoline Derivative as a Potential PET Radiotracer for Imaging CB2 Receptor
JOURNAL OF NEUROCHEMISTRY 138, 874 (2016).DOI: jnc.13716
- Inhibition of MNK pathways enhances cancer cell response to chemotherapy with temozolomide and targeted radionuclide therapy
CELLULAR SIGNALLING 28, 1412 (2016).DOI: j.cellsig.2016.06.005
- Non-invasive Imaging and Tracking of Engineered Human Muscle Precursor Cells for Skeletal Muscle Tissue Engineering Using Positron Emission Tomography
JOURNAL OF NUCLEAR MEDICINE Epub ahead of print, (2016).DOI:
- Synthesis, Radiolabeling, and Biological Evaluation of 5-Hydroxy-2-[(18)F]fluoroalkyl-tryptophan Analogues as Potential PET Radiotracers for Tumor Imaging
JOURNAL OF MEDICINAL CHEMISTRY 59, 5324 (2016).DOI: acs.jmedchem.6b00057
- (64)Cu- and (68)Ga-Based PET Imaging of Folate Receptor-Positive Tumors: Development and Evaluation of an Albumin-Binding NODAGA-Folate
MOLECULAR PHARMACEUTICS 13, 1979 (2016).DOI: acs.molpharmaceut.6b00143
- Novel chemoselective (18)F-radiolabeling of thiol-containing biomolecules under mild aqueous conditions
CHEMICAL COMMUNICATION 52, 6083 (2016).DOI: c6cc01982j
- Contribution of Auger/conversion electrons to renal side effects after radionuclide therapy: preclinical comparison of (161)Tb-folate and (177)Lu-folate
EJNMMI RESEARCH 1, 13 (2016).DOI: s13550-016-0171-1
- ImmunoPET/MR imaging allows specific detection of Aspergillus fumigatus lung infection in vivo
PNAS 113, E1026 (2016).DOI: pnas.1518836113
- Imaging quality of (44)Sc in comparison with five other PET radionuclides using Derenzo phantoms and preclinical PET
APPLIED RADIATION AND ISOTOPES 110, 129 (2016).DOI: j.apradiso.2016.01.006
- Preclinical imaging of the co-stimulatory molecules CD80 and CD86 with indium-111-labeled belatacept in atherosclerosis
EJNMMI RESEARCH 6, 1 (2016).DOI: s13550-015-0157-4
- Comparative Studies of Three Pairs of α- and γ-Conjugated Folic Acid Derivatives Labeled with Fluorine-18
BIOCONJUGATE CHEMISTRY 27, 74 (2016).DOI: acs.bioconjchem.5b00644
2015
- Ex vivo differential phase contrast and magnetic resonance imaging for characterization of human carotid atherosclerotic plaque
THE INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING 31, 1425 (2015).DOI: s10554-015-0706-y
- Folate receptor-targeted radionuclide therapy: preclinical investigation of anti-tumor effects and potential radionephropathy
NUCLEAR MEDICINE AND BIOLOGY 42, 770 (2015).DOI: j.nucmedbio.2015.06.006
- Cyclotron production of (44)Sc: From bench to bedside
NUCLEAR MEDICINE AND BIOLOGY 42, 745 (2015).DOI: j.nucmedbio.2015.05.00
- Longitudinal in vivo evaluation of bone regeneration by combined measurement of multi-pinhole SPECT and micro-CT for tissue engineering
SCIENTIFIC REPORTS 5, 10238 (2015).DOI: srep10238 Erratum DOI: srep12391
- Discovery of a high affinity and selective pyridine analog as a potential positron emission tomography imaging agent for cannabinoid type 2 receptor
JOURNAL OF MEDICINAL CHEMISTRY 58, 4266 (2015).DOI: acs.jmedchem.5b00283
- Evaluation of a Novel Tc-99m Labelled Vitamin B12 Derivative for Targeting Escherichia coli and Staphylococcus aureus In Vitro and in an Experimental Foreign-Body Infection Model
MOLECULAR IMAGING AND BIOLOGY 10, e0123443 (2015).DOI: s11307-015-0832-x
- Evaluation of ¹¹¹in-labelled exendin-4 derivatives containing different meprin β-specific cleavable linkers
PLOS ONE 10, e0123443 (2015).DOI: journal.pone.0123443
- Regional cerebral blood flow estimated by early PiB uptake is reduced in mild cognitive impairment and associated with age in an amyloid-dependent manner
NEUROBIOLOGY OF AGING 36, 1619 (2015).DOI: j.neurobiolaging.2014.12.036
- Microbial transglutaminase and c-myc-tag: a strong couple for the functionalization of antibody-like protein scaffolds from discovery platforms
CHEMBIOCHEM 16, 861 (2015).DOI: cbic.201500009
- Dosimetry and first clinical evaluation of the new 18F-radiolabeled bombesin analogue BAY 864367 in patients with prostate cancer
JOURNAL OF NUCLEAR MEDICINE 56, 372 (2015).DOI: jnumed.114.147116
- Synthesis and pharmacological evaluation of ¹¹C-labeled piperazine derivative as a PET probe for sigma-2 receptor imaging
NUCLEAR MEDICINE AND BIOLOGY 42, 399 (2015).DOI: j.nucmedbio.2014.12.018
- Evaluation of the radiolabeled boronic acid-based FAP inhibitor MIP-1232 for atherosclerotic plaque imaging
MOLUCULES 20, 2081 (2015).DOI: molecules20022081
- Investigation of the chick embryo as a potential alternative to the mouse for evaluation of radiopharmaceuticals
NUCLEAR MEDICINE AND BIOLOGY 42, 226 (2015).DOI: j.nucmedbio.2014.10.010
- Quantitative positron emission tomography of mGluR5 in rat brain with [(18) F]PSS232 at minimal invasiveness and reduced model complexity
JOURNAL OF NEUROCHEMISTRY 133, 330 (2015).DOI: jnc.13001
- Site-Specific Conjugation of Monomethyl Auristatin E to Anti-CD30 Antibodies Improves Their Pharmacokinetics and Therapeutic Index in Rodent Models
MOLECULAR PHARMACEUTICS 12, 1863 (2015).DOI: mp500666j
- Association of Long-Term Nicotine Abstinence with Normal Metabotropic Glutamate Receptor-5 Binding
BIOLOGYCAL PSYCHATRY , (2015).DOI: 10.1016/j.biopsych.2015.02.027
- Synthesis, radiolabeling and evaluation of novel 4-oxo-quinoline derivatives as PET tracers for imaging cannabinoid type 2 receptor
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 92, 554 (2015).DOI: j.ejmech.2015.01.028
- Folate Receptor-Targeted Multimodality Imaging of Ovarian Cancer in a Novel Syngeneic Mouse Model
MOLECULAR PHARMACEUTICS 12, 542 (2015).DOI: mp500628g
- Self-assembled gold coating enhances X-ray imaging of alginate microcapsules
NANOSCALE 7, 2480 (2015).DOI: c4nr06692h
- Excitation functions of natZr + p nuclear processes up to 70 MeV: New measurements and compilation
NUCLEAR INSTRUMENTS AND METHODS IN PHYSICS RESEARCH B 343, 173 (2015).DOI: j.nimb.2014.11.081
- Preclinical evaluation and test-retest studies of [(18)F]PSS232, a novel radioligand for targeting metabotropic glutamate receptor 5 (mGlu5)
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 42, 128 (2015).DOI: s00259-014-2883-7