Dr. Celestino Padeste

Senior Scientist
Celestino
Telefon
+41 56 310 21 41
Orc-ID
0000-0001-7577-5781
Paul Scherrer Institut PSI
Forschungsstrasse 111
5232 Villigen PSI
Schweiz
Digitale Visitenkarte

Main interest:
Functional Surfaces and Surface Functionalization

Research Focus:
Combination of advanced micro- and nanostructuring techniques with surface chemistry to obtain surfaces with specific properties.

2015-2019: Chemistry I in the Materials Science Bachelor Degree Course at ETHZ

Polymer Micro and Nanografting (Book)

Celestino Padeste und Sonja Neuhaus
Polymer Micro- and Nanografting
Based on own work and literature reports this book provides a summary of strategies for the formation of functional polymer patterns and structures on or in polymeric substrates using grafting processes.
Elsevier 2015; ISBN: 978-0-323-35322-9
Online Edition Elsevier Book Store

orcid.org/0000-0001-7577-5781

Papers (since 2004)

  • Czub MP, Uliana F, Grubić T, Padeste C, Rosowski KA, Lorenz C, et al.
    Phase separation of a microtubule plus-end tracking protein into a fluid fractal network
    Nature Communications. 2025; 16(1): 1165 (16 pp.). https://doi.org/10.1038/s41467-025-56468-8
    DORA PSI
  • Mortelmans T, Marty B, Kazazis D, Padeste C, Li X, Ekinci Y
    Three-dimensional microfluidic capillary device for rapid and multiplexed immunoassays in whole blood
    ACS Sensors. 2024; 9(5): 2455-2464. https://doi.org/10.1021/acssensors.4c00153
    DORA PSI
  • Gotthard G, Flores-Ibarra A, Carrillo M, Kepa MW, Mason TJ, Stegmann DP, et al.
    Fixed-target pump–probe SFX: eliminating the scourge of light contamination
    IUCrJ. 2024; 11(5): 1-13. https://doi.org/10.1107/S2052252524005591
    DORA PSI
  • Carrillo M, Mason TJ, Karpik A, Martiel I, Kepa MW, McAuley KE, et al.
    Micro-structured polymer fixed targets for serial crystallography at synchrotrons and XFELs
    IUCrJ. 2023; 10(6): 678-693. https://doi.org/10.1107/S2052252523007595
    DORA PSI
  • Moazeni M, Berger P, Padeste C
    Polymer brush structures functionalized with molecular beacon for point-of-care diagnostics
    Micro and Nano Engineering. 2023; 19: 100184 (9 pp.). https://doi.org/10.1016/j.mne.2023.100184
    DORA PSI
  • Mortelmans T, Kazazis D, Padeste C, Berger P, Li X, Ekinci Y
    Poly(methyl methacrylate)-based nanofluidic device for rapid and multiplexed serological antibody detection of SARS-CoV-2
    ACS Applied Nano Materials. 2022; 5(1): 517-526. https://doi.org/10.1021/acsanm.1c03309
    DORA PSI
  • Alpert PA, Boucly A, Yang S, Yang H, Kilchhofer K, Luo Z, et al.
    Ice nucleation imaged with X-ray spectro-microscopy
    Environmental Science: Atmospheres. 2022; 2(3): 335-351. https://doi.org/10.1039/D1EA00077B
    DORA PSI
  • Tran HT, Lucas MS, Ishikawa T, Shahmoradian SH, Padeste C
    A compartmentalized neuronal cell-culture platform compatible with cryo-fixation by high-pressure freezing for ultrastructural imaging
    Frontiers in Neuroscience. 2021; 15: 726763 (15 pp.). https://doi.org/10.3389/fnins.2021.726763
    DORA PSI
  • Martiel I, Beale JH, Karpik A, Huang C-Y, Vera L, Olieric N, et al.
    Versatile microporous polymer-based supports for serial macromolecular crystallography
    Acta Crystallographica Section D: Structural Biology. 2021; 77(9): 1153-1167. https://doi.org/10.1107/S2059798321007324
    DORA PSI
  • Martiel I, Mozzanica A, Opara NL, Panepucci E, Leonarski F, Redford S, et al.
    X-ray fluorescence detection for serial macromolecular crystallography using a JUNGFRAU pixel detector
    Journal of Synchrotron Radiation. 2020; 27: 329-339. https://doi.org/10.1107/S1600577519016758
    DORA PSI
  • Karpik A, Martiel I, Kristiansen PM, Padeste C
    Fabrication of ultrathin suspended polymer membranes as supports for serial protein crystallography
    Micro and Nano Engineering. 2020; 7: 100053 (6 pp.). https://doi.org/10.1016/j.mne.2020.100053
    DORA PSI
  • Mortelmans T, Kazazis D, Guzenko VA, Padeste C, Braun T, Li X, et al.
    Grayscale e-beam lithography: effects of a delayed development for well-controlled 3D patterning
    Microelectronic Engineering. 2020; 225: 111272 (5 pp.). https://doi.org/10.1016/j.mee.2020.111272
    DORA PSI
  • Górzny MŁ, Opara NL, Guzenko VA, Cadarso VJ, Schift H, Li XD, et al.
    Microfabricated silicon chip as lipid membrane sample holder for serial protein crystallography
    Micro and Nano Engineering. 2019; 3: 31-36. https://doi.org/10.1016/j.mne.2019.03.002
    DORA PSI
  • Makita M, Vartiainen I, Mohacsi I, Caleman C, Diaz A, Jönsson HO, et al.
    Femtosecond phase-transition in hard x-ray excited bismuth
    Scientific Reports. 2019; 9(1): 602 (7 pp.). https://doi.org/10.1038/s41598-018-36216-3
    DORA PSI
  • Casadei CM, Nass K, Barty A, Hunter MS, Padeste C, Tsai C-J, et al.
    Structure-factor amplitude reconstruction from serial femtosecond crystallography of two-dimensional membrane-protein crystals
    IUCrJ. 2019; 6: 34-45. https://doi.org/10.1107/S2052252518014641
    DORA PSI
  • Szmyt W, Calame M, Padeste C, Dransfeld C
    Nanoengineering of fibre surface for carbon fibre-carbon nanotube hierarchical composites
    In: Mouritz A, Wang C, Fox B, eds. Proceedings of the 2019 international conference on composite materials (ICCM 2019). Melbourne, Australia: RMIT University; 2019:(9 pp.). www.iccm-central.org/Proceedings/ICCM22proceedings/papers/ICCM22_Full_Paper_260.pdf.
    DORA PSI
  • Moradi M, Opara NL, Tulli LG, Wäckerlin C, Dalgarno SJ, Teat SJ, et al.
    Supramolecular architectures of molecularly thin yet robust free-standing layers
    Science Advances. 2019; 5(2): eaav4489 (7 pp.). https://doi.org/10.1126/sciadv.aav4489
    DORA PSI
  • Opara NL, Mohacsi I, Makita M, Castano-Diez D, Diaz A, Juranić P, et al.
    Demonstration of femtosecond X-ray pump X-ray probe diffraction on protein crystals
    Structural Dynamics. 2018; 5(5): 054303 (15 pp.). https://doi.org/10.1063/1.5050618
    DORA PSI
  • Szmyt W, Marot L, Calame M, Padeste C, Dransfeld C
    Carbon fibre-carbon nanotube multiscale composites - nanoengineering of the fibre surface for protection in extreme processing conditions
    In: 18th European conference on composite materials (ECCM-18). Patras: Applied Mechanics Laboratory; 2018:(9 pp.).
    DORA PSI
  • Casadei CM, Tsai C-J, Barty A, Hunter MS, Zatsepin NA, Padeste C, et al.
    Resolution extension by image summing in serial femtosecond crystallography of two-dimensional membrane-protein crystals
    IUCrJ. 2018; 5(1): 103-117. https://doi.org/10.1107/S2052252517017043
    DORA PSI
  • Seniutinas G, Weber A, Padeste C, Sakellari I, Farsari M, David C
    Beyond 100 nm resolution in 3D laser lithography — post processing solutions
    Microelectronic Engineering. 2018; 191: 25-31. https://doi.org/10.1016/j.mee.2018.01.018
    DORA PSI
  • Ranamukhaarachchi SA, Padeste C, Häfeli UO, Stoeber B, Cadarso VJ
    Design considerations of a hollow microneedle-optofluidic biosensing platform incorporating enzyme-linked assays
    Journal of Micromechanics and Microengineering. 2018; 28(2): 024002 (9 pp.). https://doi.org/10.1088/1361-6439/aa9c9c
    DORA PSI
  • Opara N, Martiel I, Arnold SA, Braun T, Stahlberg H, Makita M, et al.
    Direct protein crystallization on ultrathin membranes for diffraction measurements at X-ray free-electron lasers
    Journal of Applied Crystallography. 2017; 50(3): 909-918. https://doi.org/10.1107/S1600576717005799
    DORA PSI
  • Dübner M, Cadarso VJ, Gevrek TN, Sanyal A, Spencer ND, Padeste C
    Reversible light-switching of enzymatic activity on orthogonally functionalized polymer brushes
    ACS Applied Materials and Interfaces. 2017; 9(11): 9245-9249. https://doi.org/10.1021/acsami.7b01154
    DORA PSI
  • Dübner M, Naoum M-E, Spencer ND, Padeste C
    From pH- to light-response: postpolymerization modification of polymer brushes grafted onto microporous polymeric membranes
    ACS Omega. 2017; 2(2): 455-461. https://doi.org/10.1021/acsomega.6b00394
    DORA PSI
  • Duebner M, Cadarso VJ, Padeste C
    Photonic lab-on-a-chip device with UV light responsive smart surfaces
    In: International conference on solid-state sensors, actuators and microsystems. TRANSDUCERS 2017 - 19th international conference on solid-state sensors, actuators and microsystems. Piscataway, New Jersey: Institute of Electrical and Electronics Engineers; 2017:2199 (4 pp.)-2202. https://doi.org/10.1109/TRANSDUCERS.2017.7994513
    DORA PSI
  • Gajos K, Guzenko VA, Dübner M, Haberko J, Budkowski A, Padeste C
    Electron-beam lithographic grafting of functional polymer structures from fluoropolymer substrates
    Langmuir. 2016; 32(41): 10641-10650. https://doi.org/10.1021/acs.langmuir.6b02808
    DORA PSI
  • Arnold SA, Albiez S, Opara N, Chami M, Schmidli C, Bieri A, et al.
    Total sample conditioning and preparation of nanoliter volumes for electron microscopy
    ACS Nano. 2016; 10(5): 4981-4988. https://doi.org/10.1021/acsnano.6b01328
    DORA PSI
  • Panzarasa G, Dübner M, Pifferi V, Soliveri G, Padeste C
    ON/OFF switching of silicon wafer electrochemistry by pH-responsive polymer brushes
    Journal of Materials Chemistry C. 2016; 4(26): 6287-6294. https://doi.org/10.1039/c6tc01822j
    DORA PSI
  • Ranamukhaarachchi SA, Padeste C, Dübner M, Häfeli UO, Stoeber B, Cadarso VJ
    Integrated hollow microneedle-optofluidic biosensor for therapeutic drug monitoring in sub-nanoliter volumes
    Scientific Reports. 2016; 6: 29075 (10 pp.). https://doi.org/10.1038/srep29075
    DORA PSI
  • Dübner M, Gevrek TN, Sanyal A, Spencer ND, Padeste C
    Fabrication of thiol-ene "clickable" copolymer-brush nanostructures on polymeric substrates via extreme ultraviolet interference lithography
    ACS Applied Materials and Interfaces. 2015; 7(21): 11337-11345. https://doi.org/10.1021/acsami.5b01804
    DORA PSI
  • Huang J, Fan D, Ekinci Y, Padeste C
    Fabrication of ultrahigh resolution metal nanowires and nanodots through EUV interference lithography
    Microelectronic Engineering. 2015; 141: 32-36. https://doi.org/10.1016/j.mee.2015.01.016
    DORA PSI
  • Padeste C, Neuhaus S
    Polymer micro- and nanografting
    Waltham: Elsevier; 2015. https://doi.org/10.1016/C2014-0-00670-3
    DORA PSI
  • Panneels V, Wu W, Tsai C-J, Nogly P, Rheinberger J, Jaeger K, et al.
    Time-resolved structural studies with serial crystallography: a new light on retinal proteins
    Structural Dynamics. 2015; 2(4): 041718 (8 pp.). https://doi.org/10.1063/1.4922774
    DORA PSI
  • Dübner M, Spencer ND, Padeste C
    Light-responsive polymer surfaces via postpolymerization modification of grafted polymer-brush structures
    Langmuir. 2014; 30(49): 14971-14981. https://doi.org/10.1021/la503388j
    DORA PSI
  • Pedrini B, Tsai C-J, Capitani G, Padeste C, Hunter MS, Zatsepin NA, et al.
    7 Å resolution in protein two-dimensional-crystal X-ray diffraction at Linac Coherent Light Source
    Philosophical Transactions of the Royal Society B: Biological Sciences. 2014; 369(1647): 20130500 (5 pp.). https://doi.org/10.1098/rstb.2013.0500
    DORA PSI
  • Özçelik H, Padeste C, Hasirci V
    Systematically organized nanopillar arrays reveal differences in adhesion and alignment properties of BMSC and Saos-2 cells
    Colloids and Surfaces B: Biointerfaces. 2014; 119: 71-81. https://doi.org/10.1016/j.colsurfb.2014.03.019
    DORA PSI
  • Padeste C, Bellini S, Siewert D, Schift H
    Anti-sticking layers for nickel-based nanoreplication tools
    Microelectronic Engineering. 2014; 123: 23-27. https://doi.org/10.1016/j.mee.2014.03.039
    DORA PSI
  • Frank M, Carlson DB, Hunter MS, Williams GJ, Messerschmidt M, Zatsepin NA, et al.
    Femtosecond X-ray diffraction from two-dimensional protein crystals
    IUCrJ. 2014; 1: 95-100. https://doi.org/10.1107/S2052252514001444
    DORA PSI
  • Waser-Althaus J, Salamon A, Waser M, Padeste C, Kreutzer M, Pieles U, et al.
    Differentiation of human mesenchymal stem cells on plasma-treated polyetheretherketone
    Journal of Materials Science: Materials in Medicine. 2014; 25(2): 515-525. https://doi.org/10.1007/s10856-013-5072-5
    DORA PSI
  • Rath T, Padeste C, Vockenhuber M, Fradler C, Edler M, Reichmann A, et al.
    Direct extreme UV-lithographic conversion of metal xanthates into nanostructured metal sulfide layers for hybrid photovoltaics
    Journal of Materials Chemistry A. 2013; 1(37): 11135-11140. https://doi.org/10.1039/c3ta12592k
    DORA PSI
  • Althaus J, Padeste C, Köser J, Pieles U, Peters K, Müller B
    Nanostructuring polyetheretherketone for medical implants
    European Journal of Nanomedicine. 2012; 4(1): 7-15. https://doi.org/10.1515/ejnm-2011-0001
    DORA PSI
  • Althaus J, Urwyler P, Padeste C, Heuberger R, Deyhle H, Schift H, et al.
    Micro- and nanostructured polymer substrates for biomedical applications
    In: Lakhtakia A, Raúl J. M-P, eds. Bioinspiration, biomimetics, and bioreplication 2012. Vol. 8339. Proceedings of SPIE. Bellingham, WA, USA: SPIE; 2012:83390Q (16 pp.). https://doi.org/10.1117/12.915235
    DORA PSI
  • Neuhaus S, Spencer ND, Padeste C
    Anisotropic wetting of microstructured surfaces as a function of surface chemistry
    ACS Applied Materials and Interfaces. 2012; 4(1): 123-130. https://doi.org/10.1021/am201104q
    DORA PSI
  • Padeste C, Özelik H, Ziegler J, Schleunitz A, Bednarzik M, Yücel D, et al.
    Replication of high aspect ratio pillar array structures in biocompatible polymers for tissue engineering applications
    Microelectronic Engineering. 2011; 88(8): 1836-1839. https://doi.org/10.1016/j.mee.2010.11.051
    DORA PSI
  • Guzenko VA, Ziegler J, Savouchkina A, Padeste C, David C
    Fabrication of large scale arrays of metallic nanodots by means of high resolution e-beam lithography
    Microelectronic Engineering. 2011; 88(8): 1972 (3 pp.). https://doi.org/10.1016/j.mee.2011.02.042
    DORA PSI
  • Neuhaus S, Padeste C, Spencer ND
    Versatile wettability gradients prepared by chemical modification of polymer brushes on polymer foils
    Langmuir. 2011; 27(11): 6855-6861. https://doi.org/10.1021/la2005908
    DORA PSI
  • Neuhaus S, Padeste C, Spencer ND
    Functionalization of fluropolymers and polyolefins via grafting of polyelectrolyte brushes from atmospheric-pressure plasma activated surfacesa
    Plasma Processes and Polymers. 2011; 8(6): 512-522. https://doi.org/10.1002/ppap.201000175
    DORA PSI
  • Nygård K, Satapathy DK, Perret E, Padeste C, Bunk O, David C, et al.
    Surface-specific ordering of reverse micelles in confinement
    Soft Matter. 2010; 6(18): 4536-4539. https://doi.org/10.1039/c0sm00296h
    DORA PSI
  • Neuhaus S, Padeste C, Solak HH, Spencer ND
    Functionalization of fluoropolymer surfaces with nanopatterned polyelectrolyte brushes
    Polymer. 2010; 51(18): 4037-4043. https://doi.org/10.1016/j.polymer.2010.07.002
    DORA PSI
  • Savouchkina A, Foelske-Schmitz A, Kötz R, Wokaun A, Scherer GG, Padeste C, et al.
    Extreme ultraviolet interference lithography for generation of platinum nanoparticles on glassy carbon
    In: Bock C, Li J, Traversa E, eds. Vol. 25. ECS transactions. Pennington, NJ: The Electrochemical Society; 2010:175-184. https://doi.org/10.1149/1.3316124
    DORA PSI
  • Auzelyte V, Dais C, Farquet P, Grützmacher D, Heyderman LJ, Luo F, et al.
    Extreme ultraviolet interference lithography at the Paul Scherrer Institut
    Journal of Micro/Nanolithography, MEMS, and MOEMS. 2009; 8(2): 021204 (10 pp.). https://doi.org/10.1117/1.3116559
    DORA PSI
  • Trabadelo V, Retolaza A, Merino S, Cruz A, Heredia P, Foelske A, et al.
    Protein patterning by thermal nanoimprint lithography and NH3-plasma functionalization of polystyrene
    Journal of Vacuum Science and Technology B: Microelectronics and Nanometer Structures. 2009; 27(3): 1060-1062. https://doi.org/10.1116/1.3123304
    DORA PSI
  • Herzen J, Donath T, Pfeiffer F, Bunk O, Padeste C, Beckmann F, et al.
    Quantitative phase-contrast tomography of a liquid phantom using a conventional x-ray tube source
    Optics Express. 2009; 17(12): 10010-10018. https://doi.org/10.1364/OE.17.010010
    DORA PSI
  • Kappenberger P, Luo F, Heyderman LJ, Solak HH, Padeste C, Brombacher C, et al.
    Template-directed self-assembled magnetic nanostructures for probe recording
    Applied Physics Letters. 2009; 95(2): 023116 (3 pp.). https://doi.org/10.1063/1.3176937
    DORA PSI
  • Bunk O, Satapathy DK, Pfeiffer F, Diaz A, David C, Nygård K, et al.
    Concentration profiles of colloidal fluids in one-dimensional confinement
    Chimia. 2008; 62(10): 789-792. https://doi.org/10.2533/chimia.2008.789
    DORA PSI
  • Farquet P, Padeste C, Solak HH, Alkan Gürsel S, Scherer GG, Wokaun A
    Extreme UV radiation grafting of glycidyl methacrylate nanostructures onto fluoropolymer foils by RAFT-mediated polymerization
    Macromolecules. 2008; 41(17): 6309-6316. https://doi.org/10.1021/ma800202b
    DORA PSI
  • Zoller FA, Padeste C, Ekinci Y, Solak HH, Engel A
    Nanostructured substrates for high density protein arrays
    Microelectronic Engineering. 2008; 85(5-6): 1370-1374. https://doi.org/10.1016/j.mee.2007.12.061
    DORA PSI
  • Farquet P, Padeste C, Börner M, Ben youcef H, Alkan Gürsel S, Scherer GG, et al.
    Microstructured proton-conducting membranes by synchrotron-radiation-induced grafting
    Journal of Membrane Science. 2008; 325(2): 658-664. https://doi.org/10.1016/j.memsci.2008.08.040
    DORA PSI
  • Farquet P, Padeste C, Solak HH, Gürsel SA, Scherer GG, Wokaun A
    EUV lithographic radiation grafting of thermo-responsive hydrogel nanostructures
    Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms. 2007; 265(1): 187-192. https://doi.org/10.1016/j.nimb.2007.08.070
    DORA PSI
  • Farquet P, Kunze A, Padeste C, Solak HH, Gürsel SA, Scherer GG, et al.
    Influence of the solvent viscosity on surface graft-polymerization reactions
    Polymer. 2007; 48(17): 4936-4942. https://doi.org/10.1016/j.polymer.2007.06.052
    DORA PSI
  • Bunk O, Diaz A, Pfeiffer F, David C, Padeste C, Keymeulen H, et al.
    Confinement-induced liquid ordering investigated by x-ray phase retrieval
    Physical Review E. 2007; 75(2): 021501 (6 pp.). https://doi.org/10.1103/PhysRevE.75.021501
    DORA PSI
  • Ekinci Y, Solak HH, Padeste C, Gobrecht J, Stoykovich MP, Nealey PF
    20 nm line/space patterns in HSQ fabricated by EUV interference lithography
    Microelectronic Engineering. 2007; 84(5-8): 700-704. https://doi.org/10.1016/j.mee.2007.01.213
    DORA PSI
  • Padeste C, Farquet P, Solak HH
    Surface relief polymer structures grafted onto polymer films
    Microelectronic Engineering. 2006; 83(4-9): 1265-1268. https://doi.org/10.1016/j.mee.2006.01.152
    DORA PSI
  • Padeste C, Farquet P, Potzner C, Solak HH
    Nanostructured bio-functional polymer brushes
    Journal of Biomaterials Science, Polymer Edition. 2006; 17(11): 1285-1300. https://doi.org/10.1163/156856206778667505
    DORA PSI
  • Schift H, Saxer S, Park S, Padeste C, Pieles U, Gobrecht J
    Controlled co-evaporation of silanes for nanoimprint stamps
    Nanotechnology. 2005; 16(5): S171-S175. https://doi.org/10.1088/0957-4484/16/5/007
    DORA PSI
  • Park S, Padeste C, Schift H, Gobrecht J, Scharf T
    Chemical nanopatterns via nanoimprint lithography for simultaneous control over azimuthal and polar alignment of liquid crystals
    Advanced Materials. 2005; 17(11): 1398-1401. https://doi.org/10.1002/adma.200400989
    DORA PSI
  • Scharf T, Park S, Padeste C, Schift H, Basturk N, Grupp J
    Liquid crystal alignment on chemical nanopatterns: control over azimuthal and polar alignment
    Molecular Crystals and Liquid Crystals. 2005; 438: 55/[1619]-65/[1629]. https://doi.org/10.1080/15421400590956054
    DORA PSI
  • Gürsel SA, Padeste C, Solak HH, Scherer GG
    Microstructured polymer films by X-ray lithographic exposure and grafting
    Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms. 2005; 236(1-4): 449-455. https://doi.org/10.1016/j.nimb.2005.04.018
    DORA PSI
  • Park S, Saxer S, Padeste C, Solak HH, Gobrecht J, Schift H
    Chemical patterning of sub-50-nm half pitches via nanoimprint lithography
    Microelectronic Engineering. 2005; 78-79(1-4): 682-688. https://doi.org/10.1016/j.mee.2004.12.085
    DORA PSI
  • Stamou D, Musil C, Ulrich W-P, Leufgen K, Padeste C, David C, et al.
    Site-directed molecular assembly on templates structured with electron-beam lithography
    Langmuir. 2004; 20(9): 3495-3497. https://doi.org/10.1021/la049954j
    DORA PSI
  • Padeste C, Solak HH, Brack H-P, Slaski M, Alkan Gürsel S, Scherer GG
    Patterned grafting of polymer brushes onto flexible polymer substrates
    Journal of Vacuum Science and Technology B: Microelectronics and Nanometer Structures. 2004; 22(6): 3191-3195. https://doi.org/10.1116/1.1805542
    DORA PSI
  • Brack H-P, Padeste C, Slaski M, Alkan S, Solak HH
    Preparation of micro- and nanopatterns of polymer chains grafted onto flexible polymer substrates
    Journal of the American Chemical Society. 2004; 126(4): 1004-1005. https://doi.org/10.1021/ja0379870
    DORA PSI
  • Padeste C, Steiger B, Grubelnik A, Tiefenauer L
    Molecular assembly of redox-conductive ferrocene-streptavidin conjugates - towards bio-electrochemical devices
    Biosensors and Bioelectronics. 2004; 20(3): 545-552. https://doi.org/10.1016/j.bios.2004.03.004
    DORA PSI
  • Park S, Schift H, Padeste C, Schnyder B, Kötz Rüdiger, Gobrecht J
    Anti-adhesive layers on nickel stamps for nanoimprint lithography
    Microelectronic Engineering. 2004; 73-74: 196-201. https://doi.org/10.1016/S0167-9317(04)00098-X
    DORA PSI
  • Park S, Padeste C, Schift H, Gobrecht J
    Nanostructuring of anti-adhesive layers by hot embossing lithography
    Microelectronic Engineering. 2003; 67-68: 252-258. https://doi.org/10.1016/S0167-9317(03)00078-9
    DORA PSI
  • Padeste C, Steiger B, Grubelnik A, Tiefenauer L
    Redox labelled avidin for enzyme sensor architectures
    Biosensors and Bioelectronics. 2003; 19(3): 239-247. https://doi.org/10.1016/S0956-5663(03)00214-8
    DORA PSI
  • Steiger B, Padeste C, Grubelnik A, Tiefenauer L
    Charge transport effects in ferrocene-streptavidin multilayers immobilized on electrode surfaces
    Electrochimica Acta. 2003; 48(6): 761-769. https://doi.org/10.1016/S0013-4686(02)00746-6
    DORA PSI
  • Grubelnik A, Padeste C, Tiefenauer L
    Highly sensitive enzyme immunoassays for the detection of β-lactam antibiotics
    Food and Agricultural Immunology. 2001; 13(3): 161-169. https://doi.org/10.1080/09540100120075817
    DORA PSI
  • Sorribas H, Padeste C, Sonderegger P, Stricker C, Tiefenauer L
    Neurochips functionalized with adhesion proteins
    European Cells and Materials. 2001; 2(S1): 37-38.
    DORA PSI
  • Padeste C, Grubelnik A, Tiefenauer L
    Ferrocene-avidin conjugates for bioelectrochemical applications
    Biosensors and Bioelectronics. 2000; 15(9-10): 431-438. https://doi.org/10.1016/S0956-5663(00)00106-8
    DORA PSI
  • Tiefenauer L, Padeste C
    Micro-and nanotechnology in biosensor research
    Chimia. 1999; 53(3): 62-66. https://doi.org/10.2533/chimia.1999.62
    DORA PSI
  • Sorribas H, Padeste C, Mezzacasa T, Tiefenauer L, Leder L, Fitzli D, et al.
    Neurite outgrowth on microstructured surfaces functionalized by a neural adhesion protein
    Journal of Materials Science: Materials in Medicine. 1999; 10: 787-791. https://doi.org/10.1023/A:1008955101492
    DORA PSI
  • Padeste C, Grubelnik A, Tiefenauer L
    Amperometric immunosensing using microperoxidase MP-11 antibody conjugates
    Analytica Chimica Acta. 1998; 374(2-3): 167-176. https://doi.org/10.1016/S0003-2670(98)00466-8
    DORA PSI
  • Kossek S, Padeste C, Tiefenauer LX, Siegenthaler H
    Localization of individual biomolecules on sensor surfaces
    Biosensors and Bioelectronics. 1998; 13(1): 31-43. https://doi.org/10.1016/S0956-5663(97)00081-X
    DORA PSI
  • Tiefenauer LX, Kossek S, Padeste C, Thiébaud P
    Towards amperometric immunosensor devices
    Biosensors and Bioelectronics. 1997; 12(3): 213-223. https://doi.org/10.1016/S0956-5663(97)85339-0
    DORA PSI
  • Padeste C, Kossek S, Lehmann HW, Musil CR, Gobrecht J, Tiefenauer L
    Fabrication and characterization of nanostructured gold electrodes for electrochemical biosensors
    Journal of the Electrochemical Society. 1996; 143(12): 3890-3895. https://doi.org/10.1149/1.1837312
    DORA PSI
  • Kossek S, Padeste C, Tiefenauer L
    Immobilization of streptavidin for immunosensors on nanostructured surfaces
    Journal of Molecular Recognition. 1996; 9: 485-487. https://doi.org/10.1002/(SICI)1099-1352(199634/12)9:5/6<485::AID-JMR288>3.0.CO;2-R
    DORA PSI

Selected earlier Papers

Bio-functional Surfaces and Biosensors

C. Padeste, B. Steiger, A. Grubelnik and L. Tiefenauer, „Molecular Assembly of Redox-Conductive Ferrocene-Streptavidin Conjugates – Towards Bio-Electrochemical Devices”, Biosensors and Bioelectronics 20 (2004) 545-552.

C. Padeste, B. Steiger, A. Grubelnik and L. Tiefenauer, „Redox Labelled Avidin for Enzyme Sensor Architectures“, Biosensors and Bioelectronics, 19 (2003) 239-247.

B. Steiger, C. Padeste, A. Grubelnik and L. Tiefenauer, „Charge Transport Effects in Ferrocene-Streptavidin Multilayers Immobilised on Electrode Surfaces“, Electrochimica Acta, 48 (2003) 761-769.

H. Sorribas, C. Padeste and L. Tiefenauer, „Photolithographic Generation of Protein Micropatterns for Neuron Culture Applications“, Biomaterials 23, 3 (2002) 893-900.

A. Grubelnik, C. Padeste and L. Tiefenauer, „Highly Sensitive Immunoassays for the Detection of β-Lactam Antibiotics“, Food and Agricultural Immunology 13 (2001) 161-169.

C. Padeste, A. Grubelnik and L. Tiefenauer, „Ferrocene-Avidin Conjugates for Bioelectrochemical Applications“, Biosensors and Bioelectronics 15, 9-10 (2000) 431-438.

H. Sorribas, C. Padeste, T. Mezzacasa, L. Tiefenauer, L. Leder, D. Fitzli and P. Sonderegger, „Neurite outgrowth on microstructured surfaces functionalized by a neural adhesion protein“, J. Mat. Sci, Mat. in Medicine, 10 (1999) 787-791.

R. Ros, F. Schwesinger, C. Padeste, A. Plückthun, D. Anselmetti, H.-J. Güntherodt and L. Tiefenauer, „SPM for Functional Identification of Individual Biomolecules“, Proc. SPIE 3607 (1999) 84-89.

L. Tiefenauer and C. Padeste, „Micro- and Nanotechnology in Biosensor Research“, Chimia 53, 3 (1999) 62-65.

C. Padeste, A. Grubelnik and L. Tiefenauer, „Amperometric Immunosensing using Microperoxidase MP‑11 Antibody Conjugates“, Anal. Chim. Acta., 374 (1998) 167-176.

V. von Reding, C. Padeste, J. Spichiger, A. Grubelnik and L. Tiefenauer, „Testsystem für ampero­metrische Immunosensoren“, Bioworld 4/98 (1998) 30-32.

S. Kossek, C. Padeste, L.X. Tiefenauer and H. Siegenthaler, „Localization of Individual Biomolecules on Sensor Surfaces“, Biosensors & Bioelectronics, 13, 1 (1998) 31-43.

L.X. Tiefenauer, S. Kossek, C. Padeste and P. Thiébaud, „Towards Amperometric Immunosensor Devices“, Biosensors & Bioelectronics 12, 3 (1997) 213-223.

C. Padeste, S. Kossek, H.W. Lehmann, C.R. Musil, J. Gobrecht and L. Tiefenauer, „Fabrication and Characterization of Nanostructured Gold Electrodes for Electrochemical Biosensors“ J. Electrochemical Soc., 143, 12 (1996) 3890-3895.

S. Kossek, C. Padeste and L. Tiefenauer, „Immobilization of Streptavidin for Immunosensors on Nanostructured Surfaces“, J. Mol. Recogn. 9 (1996) 485-487.

C. Padeste, S. Kossek and L. Tiefenauer, „Modular Amperometric Immunosensor Devices“ Digest of Technical Papers of Transducers ‘95/Eurosensors IX, Stockholm, 1995, p.487-490.

(Nano)-Structuring and Surface Functionalization

S. Park, H. Schift, C. Padeste, B. Schnyder, R. Kötz and J. Gobrecht, „Anti-adhesive Layers on Nickel Stamps for Nanoimprint Lithography”, Microelectronic Engineering, 73-74 (2004) 196-201.

H. H. Solak, C. Padeste, J. Gobrecht, „Patterning of Surfaces with X-ray Interference Litho­graphy at Macromolecular Length Scales“, European Cells and Materials 6, Suppl. 1 (2003) 71.

S. Park, C. Padeste, H. Schift and Jens Gobrecht, „Nanostructuring of Anti-adhesive Layers by Hot Embossing Lithography“, Microelectronic Engineering, 67-68 (2003) 252-258.

H. Schift, L.J. Heyderman, C. Padeste and J. Gobrecht, „Chemical Nano-Patterning using Hot Embossing Lithography“, Microelectronic Engineering, 61-62 (2002) 423-428.

Surface Science and Catalysis

D.L. Trimm, C. Padeste, D.J. Pettigrew, B.Whittington and N.W. Cant, “Precious Metal-Ceria interactions in Car Exhaust Catalysts“, in R.J. MacDonald, E.C. Taglauer, K.R. Wandelt (Eds.), „Surface Science, Principles and Current Applications“, Springer, Heidelberg (1996) pp. 363-372.

C. Padeste, N.W. Cant and D.L. Trimm, „Reactions of Ceria Supported Rhodium with Hydrogen and Nitric Oxide Studied with TPR/TPO and XPS techniques“, Catal. Lett. 28 (1994) 301-311.

F. Mohammadi, P. Timbrell, S. Zhong, C. Padeste and M. Skyllas-Kazakos, „Overcharge in the Vanadium Redox Battery and Changes in Electrical Resistivity and Surface Functionality of Graphite-Felt Electrodes“ J. Power Sources, 52 (1994) 61-68.

C. Padeste, N.W. Cant and D.L. Trimm, „Thermal Decomposition of Pure and Rhodium Impregnated Cerium (III) Carbonate Hydrate in Different Atmospheres“, Catal. Lett. 24 (1994) 95-105.

S. Zhong, C. Padeste, M. Kazacos and M. Skyllas-Kazacos, „Comparison of the Physical, Chemical and Electrochemical Properties of Rayon- and Polyacrylonitrile-Based Graphite Felt Electrodes“, J. Power Sources, 45 (1993) 29-41.

C. Padeste, N.W. Cant and D. L. Trimm, „The Influence of Water on the Reduction and Reoxidation of Ceria“, Catal. Lett. 18 (1993) 305-316.

C. Padeste, D.L. Trimm and R.N. Lamb, „Characterization of Sn Doped Ni/Al2O2 Steam Reforming Catalysts by XPS“, Catal. Lett., 17 (1993) 333-339.

Solid State Chemistry

C. Padeste, H. Schmalle and H.R. Oswald, „Crystal Structure of Calcium Hydroxide Nitrate Hydrate and its Superstructure in Relation to Cadmium Hydroxide Nitrate Hydrate”, Z. Krist. 200 (1992) 35-96.

C. Padeste, A. Reller and H.R. Oswald, „The Thermal Behaviour of Pure and Nickel-Doped Hydromagnesite in Different Atmospheres“, Mat. Res. Bull. 26, 12 (1991) 1263-1268.

A. Reller, R. Emmenegger, C. Padeste and H.R. Oswald, „Thermo­chemical Reactivity of Metal Carbonates“, Chimia 45 (1991) 262-266.

C. Padeste, A. Reller and H.R. Oswald, „The Influence of Transition Metals on the Thermal Decomposition of Calcium Carbonate in Hydrogen“, Mat. Res. Bull. 25 (1990) 1299-1305.

A. Reller, H. Maurer and C. Padeste, „The Use of Solar Energy for the Generation of Organic Carbon Compounds from Natural Metal Carbonates and for the Thermochemical Reduction of Metal Oxides“, Proc. 4th Int. Symp. on Research, Development and Applications of Solar Thermal Technology, Hemisphere Publishing Corporation, New York, Washington, Philadelphia, London, 1990, p. 407.

A. Reller, C. Padeste and P. Hug, „Formation of Organic Compounds from Metal Carbonates“, Nature, 239 (1987) 527.
 

Education

  • Diploma in Chemistry and PhD in inorganic solid state chemistry, University of Zürich, Switzerland
  • Post-Doc in surface science of catalysts, University of New South Wales, Sydney, Australia


Employment At PSI / LMN since August 1993

1993-2003: Molecular Nanotechnology

  • surface design
  • surface modification
  • protein immobilization
  • electrochemical detection of labelled proteins

2003-2019: Nanofabrication Technologies / Polymer Nanotechnology

  • polymer micro- and nanografting
  • x-ray interference lithography (XIL)
  • creation of protein patterns and chemical nanopatterns
  • supports for serial crystallography

Since 2020: Member of the Mechanogenomics Group, Lab for Nanoscale Biology

  • supports for serial crystallography at XFELs and synchrotron beamlines 
  • micro and nanofabrication for bio applications