Scientific Highlights

5 novembre 2020
Teaser ERC Grant

A new generation of optogenetic tools for research and medicine

Media Releases Biology

The European Research Council (ERC) is funding an interdisciplinary collaborative project with 10 million euros for the structural and biophysical analysis of selected photoreceptors and their development into "OptoGPCRs", light-controlled molecular switches with a wide range of applications in biology and medicine.

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21 novembre 2019
Teaser Krebsmedikament aus der Neutronenquelle

Cancer medicine using PSI’s neutron source

Human Health Research Using Neutrons

At the neutron source SINQ, PSI researchers are producing special radionuclides that aid in the development of new and more effectively targeted cancer therapies. In this they collaborate closely with the clinics in the surrounding area.

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26 avril 2019
teaser adenylate cyclase

Bringing information into the cell

Media Releases Biology Human Health Medical Science

Researchers at the Paul Scherrer Institute PSI have elucidated an important part of a siganalling pathway that transmits information through the cell membrane into the interior of a cell. This exists in all mammals and plays an important role, among other things, in the regulation of the heartbeat. The new findings could lead to new therapies.

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22 août 2018

A biotechnological revolution

Biology Medical Science Human Health Radiopharmacy

Gebhard Schertler is head of the research division Biology and Chemistry at the Paul Scherrer Institute PSI and professor for Structural Biology at ETH Zurich. In this interview he talks about biological research at PSI and the future of drug development.

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14 juin 2018
teaser picture

Biological light sensor filmed in action

Media Releases Biology SwissFEL

Using X-ray laser technology, a team led by researchers of the Paul Scherrer Institute PSI has recorded one of the fastest processes in biology. In doing so, they produced a molecular movie that reveals how the light sensor retinal is activated in a protein molecule. Such reactions occur in numerous organisms. The movie shows for the first time how a protein efficiently controls the reaction of the embedded light sensor.

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30 mai 2018

Hollywood in the Würenlingen woods

SwissFEL Biology Large Research Facilities

With the X-ray laser SwissFEL, researchers at PSI want to produce movies of biomolecules in action. This can reveal how our eyes function or how new drugs work.

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8 novembre 2017

A new bio-robot

Media Releases Biology Human Health Industrial co-operation Radiopharmacy

With a new method for modifying antibodies, Philipp Spycher, winner of a Founder Fellowship at the Paul Scherrer Institute PSI, wants to develop drugs that are more stable and, thus, have fewer side-effects.

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4 octobre 2017

Highlighting the significance of structural analysis of biomolecules


The Nobel Prize in Chemistry 2017 has been awarded to Jacques Dubochet of Switzerland, U.S.-based German scientist Joachim Frank, and Richard Henderson of the United Kingdom for the development of structural analysis of single biological molecules by means of cryo-electron microscopy. The awarding of the prize underscores the fundamental significance of structural analysis of biomolecules for modern biology – a research area where the Paul Scherrer Institute PSI plays a leading role in Switzerland.

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23 février 2017

In start-up companies, getting it done is a matter of survival

Biology Medical Science Human Health

A pharmaceuticals manager at Roche for a long time, now he is the founder of a biotech firm on the campus of the Paul Scherrer Institute PSI: Michael Hennig knows the trends in the medical sector. In this interview he explains why the medicine of the future needs the innovation power of publicly funded research, and why he chose to locate his start-up leadXpro so close to PSI.

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