Prof. Dr. Manuel Guizar Sicairos

Group Leader "Computational X-ray Imaging"
Manuel Guizar-Sicairos
Institut Paul Scherrer PSI
Forschungsstrasse 111
5232 Villigen PSI

Manuel Guizar-Sicairos was appointed Associate Professor of Physics in the School of Basic Sciences (SB), Institute of Physics (IPHYS), EPF Lausanne and head of the newly formed Computational X-ray Imaging group in PSI in January 2023. His research is focused on developing methods and algorithms for computational imaging, in particular for large-scale synchrotron X-ray sources. For example for phase retrieval, X-ray coherent diffractive imaging, holography, ptychography, nanotomography, and scanning small angle X-ray scattering (sSAXS). His expertise encompasses experimental design, new imaging configurations or strategies, and devising novel reconstruction algorithms. In particular he has co-developed 3D nanoscale imaging using ptychography, magnetization vector nanotomography, small-angle scattering tensor tomography (SASTT), and leveraging sparsity for hyperspectral and dynamic nanotomography. Applications of these techniques range from imaging of the brain at synaptic resolution, bone, catalysts, and 3D operando batteries.

Manuel strongly believes in, and supports, diversity and inclusion in research. Since 2022 he is a confidential advisor for the Respect@PSI campaign.

Received his B.Sc. degree in Physics Engineering in 2002 and M.Sc. in Electronic Systems in 2005 from the Tecnológico de Monterrey, Mexico. Received a M.Sc. in Optics in 2008 and Ph.D. in Optics in 2010 from the Institute of Optics, University of Rochester in NY.

Early in 2003 joined the Photonics and Mathematical Optics Group (PMOG) and started working as a research assistant under Dr. Julio C. Gutierrez-Vega, where he was involved in research in mathematical optics, such as analysis of mode competition in unstable optical resonators (Master's dissertation), numerical methods for propagation, and non-diffracting beams. In 2005 started the Ph.D. program in optics at the Institute of Optics in Rochester NY and joined the Phase Retrieval and Imaging Science group (PRAISE), headed by Dr. James R. Fienup. My doctoral research was mainly focused on the development and advance of phase retrieval, in particular ptychography and holography, for application to high-resolution lensless imaging and wavefront measurement at X-ray wavelengths. In 2010 I joined the Coherent X-ray Scattering group, which manages and develops the cSAXS beamline, Swiss Light Source, Paul Scherrer Institut. First as a Postdoctoral Fellow in 2010, then as a tenure-track scientist in 2011. After obtaining tenure in 2014 was promoted to Senior Scientist in 2021. In 2023 Manuel was appointed head of the Computational X-ray Imaging group in a joint position with EPF Lausanne as Associate Professor of Physics.

PhD Thesis: Methods for coherent lensless imaging and x-ray wavefront measurement

Head of the Computational X-ray Imaging group. Development of a strong research program in advanced imaging, therewith supporting the research program at PSI’s large-scale facilities and EPFL. Confidential advisor for Respect@PSI.

An extensive list of publications and statistics can be found in Google Scholar Author Page or ResearcherID AAB-3793-2019. Complete list of publications and code implementations in my personal webpage. PSI affiliated publications can be found in DORA.

Selected publications (2015-2020)

  • Time-resolved imaging of three-dimensional nanoscale magnetization dynamics
    C. Donnelly, S. Finizio, S. Gliga, M. Holler, A. Hrabec, M. Odstrčil, S. Mayr, V. Scagnoli, L. J. Heyderman, M. Guizar-Sicairos, and J Raabe.
    Nature Nanotechnology (2020) [+] [SharedIt link]
  • Three-dimensional imaging of integrated circuits with macro- to nanoscale zoom
    M. Holler, M. Odstrcil, M. Guizar-Sicairos, M. Lebugle, E. Müller, S. Finizio, G. Tinti, C. David, J. Zusman, W. Unglaub, O. Bunk, J. Raabe, A. F. J. Levi, and G. Aeppli.
    Nature Electronics 2, 464-470 (2019) [DOI] [SharedIt link] [Data]
  • Three-dimensional magnetization structures revealed with X-ray vector nanotomography
    Claire Donnelly, Manuel Guizar-Sicairos, Valerio Scagnoli, Sebastian Gliga, Mirko Holler, Jörg Raabe, and Laura J. Heyderman.
    Nature 547, 328–331 (2017). [+] [SharedIt link]
  • High-resolution non-destructive three-dimensional imaging of integrated circuits
    Mirko Holler, Manuel Guizar-Sicairos, Esther H. R. Tsai, Roberto Dinapoli, Elisabeth Müller, Oliver Bunk, Jörg Raabe, and Gabriel Aeppli.
    Nature 543, 402–406 (2017). [+] [SharedIt link]
  • Nanostructure surveys of macroscopic specimens by small-angle scattering tensor tomography
    Marianne Liebi, Marios Georgiadis, Andreas Menzel, Philipp Schneider, Joachim Kohlbrecher, Oliver Bunk, and Manuel Guizar-Sicairos.
    Nature 527, 349-352 (2015). [+]