The PSI Protein Production Platform (P4)The PSI Protein Production Platform (P4) is a research facility specialized in recombinant protein production, with state-of-the-art equipment and a team of highly skilled and dedicated professionals with extensive experience in protein expression and purification. We offer recombinant protein production in bacterial, yeast, protozoan, insect and mammalian cells.
The principal aim of P4 is to support research groups at LBR and to produce high-quality protein for high-resolution structure determination by X-ray crystallography with a particular focus on membrane proteins and cytoskeletal proteins. Furthermore, P4 collaborates with research groups in Switzerland and world-wide and also offers recombinant protein production on a fee-for-service basis.
Together with the PSI Crystallization Facility, P4 represents the “gene-to-structure” pipeline designed to cover all steps from cloning to rapid mutant generation, biophysical and functional studies, as well as X-ray data collection at the SLS and high-resolution structure determination. Access to facilities for European users with an interest in membrane protein expression and/or crystallization is funded by the BioStruct-X programme.