News and Highlights
Poster Prize for Marcin Gorzny at the Swiss Nanoconvention 2017
Dr. Marcin Gorzny, Post-Doc at LMN in the PSI career return program recieved a poster prize at the Swiss Nanoconvention 2017 for his contribution entitled: "Silicon chip as lipid membrane holder for serial crystallography experiments".
A new method of material modification using 172 nm UV photons enables to fabricate ultra-smooth and self-optimized polymer surfaces. The method, published in Advanced Materials Technologies, was used in the production of high quality micro-optics to remove typical process flaws after a 2-photon-lithography process.
Light-switching of enzymatic activity in functionalized polymer brushes
UV- and visible light-induced switching of enzymatic activity has been demonstrated using surface-grafted polymer brushes functionalized with microperoxidase MP-11 and spiropyran mojeties. Integration into an optofluidic device allowed reversible switching of the enzymatic activity under flow.
Technology award for microneedle-optofluidic sensor System
Sahan Ranamukhaarachchi, PhD student from UBC in Vancouver, won the 2016 "Brian L. Barge Award for Excellence in Microsystems Integration" for his work on a biosensing platform with integrated hollow microneedles carried out at PSI in 2015 in collaboration with Dr. Victor Cadarso and Dr. Celestino Padeste.
Therapeutic drug monitoring in sub-nanoliter volumes
A promising system for painless and minimally-invasive therapeutic drug monitoring has been demonstrated. The proposed device combines biofunctionalized hollow microneedles with an optofluidic system to measure drug concentrations in volumes as small as 0.6 nL.
- Nanoimprint Lithography (NIL)
- Stamps and molds with high resolution and 3D surface topographies
- Antisticking layers for molds and patterning with chemical contrast
Applied Projects (in Collaboration with Partners)
- Nanoimprint Lithography process development (also known as Hot Embossing Lithography), within the framework of Emerging Nanopatterning Methods development in the EU integrated program NaPa (2004-2008) and the EU large program NaPANIL (2008-2012).
- Nanomanufacturing processes for arbitrary 3-dimensional surfaces in the fields of optical components and life sciences
- Injection molded polymeric micro cantilevers for biosensing
- Antiadhesive coatings for silicon, hybrid organic-inorganic polymers and Nickel
- Nanoporous chips for investigation of bio-membrane transport
- Surface patterning of polymers and antiadhesive coatings
- Variotheral injection molding, roll embossing and thermoforming
- Joint European projects with partners in the EU-FP6 Integrated Project “NaPa” Emerging Nanopatterning Methods (2004-2008) and “NaPANIL” (2008-2012)
- Collaborations in the CNMM programme with partners in Korea (2008-2012)
- Applied projects with industrial partners in the framework of CTI, NCCR and NanoArgovia
- Center for Cellular Imaging and NanoAnalytics Biozentrum, University of Basel
- Laboratory for Surface Science and Technology (LSST), Department of Materials, ETH Zürich
- BIOMAT - Biomaterials and Tissue Engineering Research Laboratory, METU, Ankara
- Partners in PSI
Competencies for Partnership in Research Projects
- Thermal nanoimprint lithography up to 180 mm wafer size, UV up to 150 mm wafer size with experience in process development, polymer rheology and applications
- Stamp manufacturing using e-beam lithography
- Antiadhesive coatings for imprint and injection molding using silane chemistry
- Fabrication of micro- and nanostructures for microfluidics, optics and surface topography