New insights into the workings of important drug receptorsMany medical drugs operate on specific receptors located in the outer walls of our body’s cells. One of these is called the beta-1 adrenergic receptor. Among other things, it is responsible for palpitation, the racing pulse that we feel with stage fright or infatuation. How it transmits signals to the cellular interior can now be revealed in detail. These findings could help scientists better understand many drugs' mode of action.
Interview with Stefan Janssen, Head of the User OfficeStefan Janssen is Head of the User Office at Paul Scherrer Institute PSI. In an interview, he explains why the PSI’s large research facilities are popular with researchers coming from other institutions, how he handles the many applications and how he supports users who come here to conduct experiments.
Computers and other electronic devices account for a substantial portion of worldwide energy use. With today’s technologies, it is not possible to reduce this energy consumption significantly any further; chips in the energy-saving electronics of the future will hence have to be made from novel materials. Researchers at the Paul Scherrer Institute PSI have now found important clues in the search for such materials.
On application of the ETH Board, the Federal Council reappointed the Director of the Paul Scherrer Institute PSI, Joël Mesot, and the Director of the Swiss Federal Institute for Forest, Snow and Landscape Research WSL, Konrad Steffen, for another four years on 20 January 2016. Joël Mesot’s third term of office will start on 1 August 2016, Konrad Steffen’s second term of office on 1 July 2016.
There are tumours where nothing seems to help: not chemotherapy, not external radiation therapy, not an operation. Often, they have already metastasised and can no longer be destroyed using conventional methods. The only option left here is internal radiotherapy with targeted radioactive drugs that strike directly at the heart of the disease. In order to make this possible, twenty specialists have been conducting research at the Centre for Radiopharmaceutical Sciences at the Paul Scherrer Institute PSI, a joint facility of PSI, ETH Zurich and the University Hospital Zurich.
Usually, superconductors expel magnetic fields. In type II superconductors, however, thin channels – so-called flux tubes – are formed. The magnetic field is guided through these tubes while the rest of the material remains field-free and superconducting. In the metal niobium, the flux tubes bunch together into small islands that create complex patterns similar to those found in other fields of nature. A team of researchers from PSI and TU München were the first to conduct neutron experiments to study these patterns in niobium and determine the distribution of the islands in detail.
Since the autumn of 2015, the SwissFEL beam tunnel has been filling up with the machine components for the new PSI large research facility. Piece by piece, the pre-assembled components are being brought to their final destination.
What does a physicist do when his experiment needs an extremely precise time measurement? So precise that existing electronics cannot help him? A scientist from the Paul Scherrer Institute PSI simply decided to develop his own solution. The result is called DRS4, a high-precision electronic chip that could unlock the physics of our entire universe. As an additional benefit, the chip is already helping doctors to localise brain tumours with great accuracy.
Allen Warnungen vor den Folgen des Klimawandels zum Trotz und unbeeindruckt von politischen Absichtserklärungen: Die weltweiten Kohlendioxidemissionen steigen und steigen. Hauptverantwortlich dafür sind Kohle- und Gaskraftwerke, die den zunehmenden Strombedarf decken. Könnte man deren Kohlendioxidemissionen dauerhaft im Boden speichern, anstatt damit Atmosphäre und Klima zu belasten? Und wäre das auch für die Schweiz interessant? Diese Fragen beleuchtet der neueste Energie-Spiegel des PSI.This news release is only available in German.
Bones are made up of tiny fibres that are roughly a thousand times finer than a human hair. Researchers at the Paul Scherrer Institute PSI have developed a new computer-based algorithm with which they were able to visualize the localised order and alignment of these nanostructures inside an entire piece of bone for the first time.
In a series of experiments at the Swiss Light Source SLS, physicists from the Paul Scherrer Institute PSI have discovered a particle, the existence of which was predicted eighty-six years ago. It is a member of the particle family that also includes the electron, the carrier of electrical currents. The particle now discovered is massless and can exist only within a special class of materials known as Weyl semi-metals.
When bridges, dam walls and other structures made of concrete are streaked with dark cracks after a few decades, the culprit is the so-called the concrete disease. Researchers from the Paul Scherrer Institute PSI and Empa have now solved the structure of the material produced in these cracks at atomic level - and have thereby discovered a previously unknown crystalline arrangement of the atoms.
At first glance, the Swiss Light Source SLS stands out as a striking building. The inside reveals a setting of cutting-edge research. A journey through a world where electrons race a slalom course and X-rays help decode proteins.
Researchers from the Paul Scherrer Institute PSI have succeeded in using commercially available camera technology to visualise terahertz light. In doing so, they are enabling a low-cost alternative to the procedure available to date, whilst simultaneously increasing the comparative image resolution by a factor of 25. The special properties of terahertz light make it potentially advantageous for many applications. At PSI, it will be used for the experiments on the X-ray free-electron laser SwissFEL.
The Paul Scherrer Institute PSI is involved in a project conducted by several research institutes (spearheaded by EPFL) to devise an X-ray machine especially for developing countries. The device should be able to cope with tropical climes and be easy and cheap to repair. PSI researchers are focusing on producing a cost-effective detector that is necessary for the imaging. The detector registers the X-ray light much like a chip in a digital camera.
Microscopic deviations from the ideal structure render uranium dioxide, the fuel commonly used in nuclear power plants, more resistant to radiation damage.
Our universe consists of significantly more matter than existing theories are able to explain. This is one of the great puzzles of modern science. One way to clarify this discrepancy is via the neutron’s so-called electric dipole moment. In an international collaboration, researchers at PSI have now devised a new method which will help determine this dipole moment more accurately than ever before.
Interview with Luc PattheyLuc Patthey is in charge of designing and implementing the beamlines for the X-ray free-electron laser SwissFEL. In this Interview, he explains the requirements the beamlines need to meet for the X-ray light pulses generated by SwissFEL to reach the experiments in an optimal form and what role collaborations play in the development of beamlines.
Researchers from the Paul Scherrer Institute (PSI) have developed a coating technique in the laboratory conditions that could raise the efficiency of fuel cells. The PSI scientists have already applied to patent the technique, which is suitable for mass production.
Researchers at the Paul Scherrer Institute (PSI) created a synthetic material out of 1 billion tiny magnets. Astonishingly, it now appears that the magnetic properties of this so-called metamaterial change with the temperature, so that it can take on different states; just like water has a gaseous, liquid and a solid state.