Biointerfaces: Enabling Technology for Bio-Research
Integrated microneedle-optofluidic biosensor In an international collaboration between the University of the British Columbia (UBC) and the Paul Scherrer Institut (PSI), a promising system for painless and minimally-invasive therapeutic drug monitoring has been demonstrated. The proposed device is based on the combination of an optofluidic system with hollow microneedles to extract extremely small volumes (< 1 nL) of interstitial fluid (ISF) to measure drug concentrations. >>read more
VEGF-Patterns Based on photolithograpghy or on microfluidics we were producing patterns of proteins of the VEGF-Family. Studies of porcine aortic endothelial cells (PAE cells) cultured on the substrates enable new insights into the mechanisms deteriming blood vessel formation which are highly dependent on the presence and distribution of VEGF-proteins. In collaboration with Kurt Ballmer, molecular cell biology at PSI.