Lab News & Scientific Highlights

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"Ultimately, we aim to understand how diseases start in single cells"

Biology Health Innovation Medical Science Proton Therapy

Imaging and sequencing techniques combined with machine learning offer researchers countless opportunities to look inside cells with greater precision than ever before. G.V. Shivashankar, lab head at PSI, describes how such information can be used to find answers to pressing questions.

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Teaser ERC Grant

A new generation of optogenetic tools for research and medicine

Media Releases Biology

The European Research Council (ERC) is funding an interdisciplinary collaborative project with 10 million euros for the structural and biophysical analysis of selected photoreceptors and their development into "OptoGPCRs", light-controlled molecular switches with a wide range of applications in biology and medicine.

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Petr Skopintsev (links), Jörg Standfuss (Mitte) und Christopher Milne (rechts) an der Experimentierstation Alvra am Freie-Elektronen-Röntgenlaser SwissFEL

Elucidating the mechanism of a light-driven sodium pump

Media Releases SwissFEL Biology

Researchers at the Paul Scherrer Institute PSI have succeeded for the first time in recording a light-driven sodium pump from bacterial cells in action. The findings promise progress in developing new methods in neurobiology. The researchers used the new X-ray free-electron laser SwissFEL for their investigations.

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Teaser Krebsmedikament aus der Neutronenquelle

Cancer medicine using PSI’s neutron source

Health Innovation Research Using Neutrons

At the neutron source SINQ, PSI researchers are producing special radionuclides that aid in the development of new and more effectively targeted cancer therapies. In this they collaborate closely with the clinics in the surrounding area.

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teaser adenylate cyclase

Bringing information into the cell

Media Releases Biology Health Innovation Medical Science

Researchers at the Paul Scherrer Institute PSI have elucidated an important part of a siganalling pathway that transmits information through the cell membrane into the interior of a cell. This exists in all mammals and plays an important role, among other things, in the regulation of the heartbeat. The new findings could lead to new therapies.

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teaser picture

Biological light sensor filmed in action

Media Releases SwissFEL Biology

Using X-ray laser technology, a team led by researchers of the Paul Scherrer Institute PSI has recorded one of the fastest processes in biology. In doing so, they produced a molecular movie that reveals how the light sensor retinal is activated in a protein molecule. Such reactions occur in numerous organisms. The movie shows for the first time how a protein efficiently controls the reaction of the embedded light sensor.

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Dies ist ein Text aus dem PSI-Medien-Archiv. Die Inhalte sind möglicherweise veraltet.

Hollywood in the Würenlingen woods

SwissFEL Biology Large Research Facilities

With the X-ray laser SwissFEL, researchers at PSI want to produce movies of biomolecules in action. This can reveal how our eyes function or how new drugs work.

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Dies ist ein Text aus dem PSI-Medien-Archiv. Die Inhalte sind möglicherweise veraltet.

A new bio-robot

Media Releases Biology Health Innovation Industrial co-operation Radiopharmacy

With a new method for modifying antibodies, Philipp Spycher, winner of a Founder Fellowship at the Paul Scherrer Institute PSI, wants to develop drugs that are more stable and, thus, have fewer side-effects.

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Dies ist ein Text aus dem PSI-Medien-Archiv. Die Inhalte sind möglicherweise veraltet.