Research
Topics
Research at the SLS MX group is focused around beamline development, as well as on the development and study of methods and techniques related to X-ray diffraction.Highlights
Mueller, M., Wang, M., Schulze-Briese, C. (2012) Optimal fine ϕ-slicing for single-photon-counting pixel detectors. Acta Crystallogr D Biol Crystallogr. Jan;68(Pt 1):42-56. Epub 2011 Dec 9. http://www.ncbi.nlm.nih.gov/pubmed/22194332. link to paper.Publications of the MX Group
2012
Graef C., Schacherl M., Waltersperger S., Baumann U., Crystal structures of archaemetzincin reveal a moldable substrate-binding site. PLOS One. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0043863Chong H., Yao X., Sun J., Qiu Z., Zhang M., Waltersperger S., Wang M., Cui S., He Y., The M-T hook structure is critical for design of HIV-1 fusion inhibitors. J Biol Chem. http://www.jbc.org/content/early/2012/08/09/jbc.M112.390393.long
Yao X., Chong H., Zhang C., Qiu Z., Qin B., Han R., Waltersperger S., Wang M., He Y., Cui S., Structural Basis of Potent and Broad HIV-1 Fusion Inhibitor CP32M. J Biol Chem. http://www.jbc.org/content/287/32/26618
Pham SQ., Pompidor G., Liu J., Li XD., Li Z. (2012) Evolving P450pyr hydroxylase for highly enantioselective hydroxylation at non-activated carbon atom. Chem Commun May 14;48(38):4618-20. http://www.ncbi.nlm.nih.gov/pubmed/22430002
Mueller U., Darowski N., Fuchs MR., Förster R., Hellmig M., Paithankar KS., Pühringer S., Steffien M., Zocher G., Weiss MS. (2012) Facilities for macromolecular crystallography at the Helmholtz-Zentrum Berlin. J Synchrotron Radiat. May;19(Pt 3):442-9. http://www.ncbi.nlm.nih.gov/pubmed/22514183
Zarrine-Afsar A., Barends TR., Müller C., Fuchs MR., Lomb L., Schlichting I., Miller RJ. (2012) Crystallography on a chip. Acta D Mar;68(Pt 3):321-3. http://www.ncbi.nlm.nih.gov/pubmed/22349234
He C., Fuchs MR., Ogata H, Knipp M. (2012) Guanidine-ferroheme coordination in the mutant protein nitrophorin 4(AUTHOR_WWW/SLS/PXI.L130R). Angew Chem Int Ed Engl. Apr 27;51(18):4470-3. http://www.ncbi.nlm.nih.gov/pubmed/22334402
Cousido-Siah A., Ayoub D., Berberián G., Bollo M., Van Dorsselaer A., Debaene F., Dipolo R., Petrova T., Schulze-Briese C., Olieric V., Esteves A., Mitschler A., Sanglier-Cianférani S., Beaugé L., Podjarny A. (2012) Structural and functional studies of ReP1-NCXSQ, a protein regulating the squid nerve Na(+)/Ca(2+) exchanger. Acta D Sep;68(Pt 9):1098-107. http://www.ncbi.nlm.nih.gov/pubmed/22948910
Chong H., Yao X., Qiu Z., Qin B., Han R., Waltersperger S., Wang M., Cui S., He Y., Discovery of Critical Residues for Viral Entry and Inhibition through Structural Insight of HIV-1 Fusion Inhibitor CP621–652 J Biol Chem. http://www.jbc.org/content/287/24/20281
Wang N., Wang M., Gao Y., Ran T., Lan Y., Wang J., Xu L., Wang W., (2012) Crystallization and preliminary X-ray crystallographic analysis of a blue-light-absorbing proteorhodopsin. ActaF 2012 Mar 1;68(Pt 3):281-3.
Sun L., Chen Y., Rajendran C., Mueller U., Panjikar S., Wang M., Mindnich R., Rosenthal C., Penning T.M., Stoeckigt J. Crystal structure of perakine reductase, a founding member of a novel Aldo-Keto reductase (AKR) subfamily which undergoes unique conformational changes during NADPH binding. J Biol Chem. http://www.ncbi.nlm.nih.gov/pubmed/22334702
Zou T.T., Yao X., Qin B., Zhang M., Cai L.F., Shang W., Svergun D.I., Wang M., Cui S., Jin Q., (2012) Crystal Structure of Pseudomonas aeruginosa Tsi2 Reveals a Stably Folded Superhelical Antitoxin. J Mol Biol. http://www.ncbi.nlm.nih.gov/pubmed/22310046.
Wu, F., Zhu, H., Sun, L., Rajendran, C., Wang, M., Ren, X., Panjikar, S., Cherkasov, A., Zou, H., Stöckigt, J. (2012) Scaffold Tailoring by a Newly Detected Pictet-Spenglerase Activity of Strictosidine Synthase: From the Common Tryptoline Skeleton to the Rare Piperazino-indole Framework. J Am Chem Soc. http://www.ncbi.nlm.nih.gov/pubmed/22229634.
Yao, X., Chong, H., Zhang, C., Waltersperger, S., Wang, M.,, Cui, S., He, Y. (2012) Broad antiviral activity and crystal structure of HIV-1 fusion inhibitor Sifuvirtide. J Biol Chem.. http://www.ncbi.nlm.nih.gov/pubmed/22228771.
Mueller, M., Wang, M., Schulze-Briese, C. (2012) Optimal fine ϕ-slicing for single-photon-counting pixel detectors. Acta Crystallogr D Biol Crystallogr. Jan;68(Pt 1):42-56. Epub 2011 Dec 9. http://www.ncbi.nlm.nih.gov/pubmed/22194332. link to paper.
Xia, L., Ruppert, M., Wang, M., Santosh, P., Lin, H., Rajendran, C., Barleben, L., and Stöckigt, J. (2012) Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity. ACS Chem Biol.. PMID: 22004291. http://www.ncbi.nlm.nih.gov/pubmed/22004291.
2011
Faro AR., Carpentier P., Jonasson G., Pompidor G., Arcizet D., Demachy I., Bourgeois D. (2011) Low-temperature chromophore isomerization reveals the photoswitching mechanism of the fluorescent protein Padron. J Am Chem Soc. http://www.ncbi.nlm.nih.gov/pubmed/21923132Blaise, M., Fréchin, M., Olieric, V., Charron, C., Sauter, C., Lorber, B., Roy, H., and Kern, D. (2011) Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases. Journal of Molecular Biology. http://www.ncbi.nlm.nih.gov/pubmed/21820443.
Wang, J., Fan, T., Yao, X., Wu, Z., Guo, L., Lei, X., Wang, J., Wang, M., Jin, Q., Cui, S. (2011) Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of the Catalytically Important Residues. Journal of Virology. 85(19):10021-30, http://www.ncbi.nlm.nih.gov/pubmed/21813612.
Cui, S., Wang, J., Fan, T., Qin, B., Guo, L., Lei, X., Wang, J., Wang, M., and Jin, Q. (2011) Crystal structure of human enterovirus 71 3C protease. Journal of Molecular Biology 408, 449-461. http://www.ncbi.nlm.nih.gov/pubmed/21396941.
Glettig, W., Vitins, M., Schwarb, A., Maag, S., and Schulze-Briese, C. (2011) First Results from PRIGO III, the Parallel Robotics Inspired Goniometer for Protein Crystallography. Proceedings of the 11th Euspen International Conference.
Kitagawa, D., Vakonakis, I., Olieric, N., Hilbert, M., Keller, D., Olieric, V., Bortfeld, M., Erat, M. C., Flückiger, I., Gönczy, P., and Steinmetz, Michel O (2011) Structural Basis of the 9-Fold Symmetry of Centrioles. Cell 144, 1-12. http://www.ncbi.nlm.nih.gov/pubmed/21277013.
Navdaeva, V., Zurbriggen, A., Waltersperger, S., Schneider, P., Oberholzer, A. E., Bähler, P., Bächler, C., Grieder, A., Baumann, U., and Erni, B. (2011) Phosphoenolpyruvate: sugar phosphotransferase system from the hyperthermophilic Thermoanaerobacter tengcongensis. Biochemistry 50, 1184-1193. http://www.ncbi.nlm.nih.gov/pubmed/21250658.
Pauluhn, A., Pradervand, C., Rossetti, D., Salathe, M., and Schulze-Briese, C. (2011) Automatic loop centring with a high-precision goniometer head at the SLS macromolecular crystallography beamlines. Journal of Synchrotron Radiation 18, 595–600. http://scripts.iucr.org/cgi-bin/paper?S0909049511011848.
Rajendran, C., Dworkowski, F. S. N., Wang, M., and Schulze-Briese, C. (2011) Radiation damage in room-temperature data acquisition with the PILATUS 6M pixel detector. Journal of Synchrotron Radiation 18, 318-328. http://www.ncbi.nlm.nih.gov/pubmed/21525639.
Schellenberger, P., Demangeat, G., Lemaire, O., Ritzenthaler, C., Bergdoll, M., Oliéric, V., Sauter, C., and Lorber, B. (2011) Strategies for the crystallization of viruses: using phase diagrams and gels to produce 3D crystals of Grapevine fanleaf virus. Journal of Structural Biology 174, 344-51. http://www.ncbi.nlm.nih.gov/pubmed/21352920.
Vaart, B. van der, Manatschal, C., Grigoriev, I., Olieric, V., Gouveia, S. M., Bjelic, S., Demmers, J., Vorobjev, I., Hoogenraad, C. C., Steinmetz, M. O., and Akhmanova, a (2011) SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase. The Journal of Cell Biology. http://www.jcb.org/cgi/doi/10.1083/jcb.201012179.
Wolff, P., Olieric, V., Briand, J. P., Chaloin, O., Dejaegere, A., Dumas, P., Ennifar, E., Guichard, G., Wagner, J., and Burnouf, D. Y. (2011) Structure-based design of short peptide ligands binding onto the E.coli processivity ring. Journal of Medicinal Chemistry. http://www.ncbi.nlm.nih.gov/pubmed/21619076.
2010
Butschi, A., Titz, A., Wälti, M. A., Olieric, V., Paschinger, K., Nöbauer, K., Guo, X., Seeberger, P. H., Wilson, I. B. H., Aebi, M., Hengartner, M. O., and Künzler, M. (2010) Caenorhabditis elegans N-glycan core beta-galactoside confers sensitivity towards nematotoxic fungal galectin CGL2. PLoS Pathogens 6, e1000717. http://www.ncbi.nlm.nih.gov/pubmed/20062796.Koch, M., Diez, J., Wagner, A., and Fritz, G. (2010) Crystallization and calcium/sulfur SAD phasing of the human EF-hand protein S100A2. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications 66, 1032-1036. http://www.ncbi.nlm.nih.gov/pubmed/20823519.
Meents, A., Gutmann, S., Wagner, A., and Schulze-Briese, C. (2010) Origin and temperature dependence of radiation damage in biological samples at cryogenic temperatures. Proceedings of the National Academy of Sciences of the United States of America 107, 1094-1099. http://www.ncbi.nlm.nih.gov/pubmed/20080548.
Rajendran, C., Ermler, U., Ludwig, B., and Michel, H. (2010) Structure at 1.5 A resolution of cytochrome c(552) with its flexible linker segment, a membrane-anchored protein from Paracoccus denitrificans. Acta Crystallographica. Section D, Biological Crystallography 66, 850-854. http://www.ncbi.nlm.nih.gov/pubmed/20606266.
Truan, D., Huergo, L. F., Chubatsu, L. S., Merrick, M., Li, X.-D., and Winkler, F. K. (2010) A new P(II) protein structure identifies the 2-oxoglutarate binding site. Journal of Molecular Biology 400, 531-539. http://www.ncbi.nlm.nih.gov/pubmed/20493877.
Waltersperger, S., Widmer, C., Wang, M., and Baumann, U. (2010) Crystal structure of archaemetzincin AUTHOR_WWW/SLS/PXI.AmzA from Methanopyrus kandleri at 1.5 A resolution._ Proteins_ 78, 2720-2723. http://www.ncbi.nlm.nih.gov/pubmed/20597090.
Wu, M., Le, H. D., Wang, M., Yurkov, V., Omelchenko, A., Hnatowich, M., Nix, J., Hryshko, L. V., and Zheng, L. (2010) Crystal structures of progressive Ca2+ binding states of the Ca2+ sensor Ca2+ binding domain 1 (CBD1) from the CALX Na+/Ca2+ exchanger reveal incremental conformational transitions. The Journal of Biological Chemistry 285, 2554-2561. http://www.ncbi.nlm.nih.gov/pubmed/19815561.
Yeh, J. I., Pohl, E., Truan, D., He, W., Sheldrick, G. M., Du, S., and Achim, C. (2010) The crystal structure of non-modified and bipyridine-modified PNA duplexes. Chemistry 16, 11867-11875. http://www.ncbi.nlm.nih.gov/pubmed/20859960.
2009
Bosak, A., Hoesch, M., Krisch, M., Chernyshov, D., Pattison, P., Schulze-Briese, C., Winkler, B., Milman, V., Refson, K., Antonangeli, D., and Farber, D. (2009) 3D imaging of the Fermi surface by thermal diffuse scattering. Physical Review Letters 103, 076403. http://www.ncbi.nlm.nih.gov/pubmed/19792668.Bullock, A. N., Russo, S., Amos, A., Pagano, N., Bregman, H., Debreczeni, J. E., Lee, W. H., Delft, F. von, Meggers, E., and Knapp, S. (2009) Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor. PloS One 4, e7112. http://www.ncbi.nlm.nih.gov/pubmed/19841674.
Coulibaly, F., Chiu, E., Gutmann, S., Rajendran, C., Haebel, P. W., Ikeda, K., Mori, H., Ward, V. K., Schulze-Briese, C., and Metcalf, P. (2009) The atomic structure of baculovirus polyhedra reveals the independent emergence of infectious crystals in DNA and RNA viruses. Proceedings of the National Academy of Sciences of the United States of America 106, 22205-22210. http://www.ncbi.nlm.nih.gov/pubmed/20007786.
Glettig, W., Henein, S., Breguet, J.-M., and Schulze-Briese, C. (2009) PRIGO: Parallel Robotics Inspired Goniometer for Protein Crystallography. Proceedings of the 9th Euspen International Conference 1, 192.
Oberholzer, A. E., Bumann, M., Hege, T., Russo, S., and Baumann, U. (2009) Metzincinʼs canonical methionine is responsible for the structural integrity of the zinc-binding site. Biological Chemistry 390, 875-881. http://www.ncbi.nlm.nih.gov/pubmed/19558324.
Olieric, V., Rieder, U., Lang, K., Serganov, A., Schulze-Briese, C., Micura, R., Dumas, P., and Ennifar, E. (2009) A fast selenium derivatization strategy for crystallization and phasing of RNA structures. Rna New York Ny 15, 707-715. http://www.ncbi.nlm.nih.gov/pubmed/19228585.
Oliéric, V., Wolff, P., Takeuchi, A., Bec, G., Birck, C., Vitorino, M., Kieffer, B., Beniaminov, A., Cavigiolio, G., Theil, E., Allmang, C., Krol, A., and Dumas, P. (2009) SECIS-binding protein 2, a key player in selenoprotein synthesis, is an intrinsically disordered protein. Biochimie 91, 1003-9. http://www.ncbi.nlm.nih.gov/pubmed/19467292.
Owen, R. L., Holton, J. M., Schulze-Briese, C., and Garman, E. F. (2009) Determination of X-ray flux using silicon pin diodes. Journal of Synchrotron Radiation 16, 143-151. http://www.ncbi.nlm.nih.gov/pubmed/19240326.
Owen, R. L., Pearson, A. R., Meents, A., Boehler, P., Thominet, V., and Schulze-Briese, C. (2009) A new on-axis multimode spectrometer for the macromolecular crystallography beamlines of the Swiss Light Source. Journal of Synchrotron Radiation 16, 173-182. http://www.ncbi.nlm.nih.gov/pubmed/19240329.
Russo, S., Schweitzer, J.-E., Polen, T., Bott, M., and Pohl, E. (2009) Crystal structure of the caseinolytic protease gene regulator, a transcriptional activator in actinomycetes. The Journal of Biological Chemistry 284, 5208-5216. http://www.ncbi.nlm.nih.gov/pubmed/19019826.
Wagner, A., Diez, J., Schulze-Briese, C., and Schluckebier, G. (2009) Crystal structure of ultralente--a microcrystalline insulin suspension. Proteins 74, 1018-1027. http://www.ncbi.nlm.nih.gov/pubmed/18767151.
Wu, M., Wang, M., Nix, J., Hryshko, L. V., and Zheng, L. (2009) Crystal structure of CBD2 from the Drosophila Na(+)/Ca(2+) exchanger: diversity of Ca(2+) regulation and its alternative splicing modification. Journal of Molecular Biology 387, 104-112. http://www.ncbi.nlm.nih.gov/pubmed/19361442.
Yang, L., Hill, M., Wang, M., Panjikar, S., and Stöckigt, J. (2009) Structural basis and enzymatic mechanism of the biosynthesis of C9- from C10-monoterpenoid indole alkaloids. Angewandte Chemie 48, 5211-3. http://www.ncbi.nlm.nih.gov/pubmed/19496101.
2008
Blaise, M., Olieric, V., Sauter, C., Lorber, B., Roy, B., Karmakar, S., Banerjee, R., Becker, H. D., and Kern, D. (2008) Crystal structure of glutamyl-queuosine tRNAAsp synthetase complexed with L-glutamate: structural elements mediating tRNA-independent activation of glutamate and glutamylation of tRNAAsp anticodon. Journal of Molecular Biology 381, 1224-1237. http://www.ncbi.nlm.nih.gov/pubmed/18602926.Felderer, K., Groves, M., Diez, J., Pohl, E., and Witt, S. (2008) Crystallization and preliminary X-ray analysis of the Thermoplasma acidophilum 20S proteasome in complex with protein substrates. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications 64, 899-902. http://www.ncbi.nlm.nih.gov/pubmed/18931431.
Koch, M., Diez, J., and Fritz, G. (2008) Crystal structure of Ca2+ -free AUTHOR_WWW/SLS/PXI.S100A2 at 1.6-A resolution. Journal of Molecular Biology 378, 933-942. http://www.ncbi.nlm.nih.gov/pubmed/18394645.
Lucarelli, D., Vasil, M. L., Meyer-Klaucke, W., and Pohl, E. (2008) The Metal-Dependent Regulators AUTHOR_WWW/SLS/PXI.FurA and AUTHOR_WWW/SLS/PXI.FurB from Mycobacterium Tuberculosis. International Journal of Molecular Sciences 9, 1548-1560. http://www.ncbi.nlm.nih.gov/pubmed/19169435.
Malo, G. D., Wang, M., Wu, D., Stelling, A. L., Tonge, P. J., and Wachter, R. M. (2008) Crystal structure and Raman studies of dsFP483, a cyan fluorescent protein from Discosoma striata. Journal of Molecular Biology 378, 871-886. http://www.ncbi.nlm.nih.gov/pubmed/18395223.
Pauluhn, A., Ahmed, H., Lorentzen, E., Buchinger, S., Schomburg, D., Siebers, B., and Pohl, E. (2008) Crystal structure and stereochemical studies of KD(P)G aldolase from Thermoproteus tenax. Proteins 72, 35-43. http://www.ncbi.nlm.nih.gov/pubmed/18186475.
Steinmetz, M. O., Gattin, Z., Verel, R., Ciani, B., Stromer, T., Green, J. M., Tittmann, P., Schulze-Briese, C., Gross, H., Gunsteren, W. F. van, Meier, B. H., Serpell, L. C., Müller, S. A., and Kammerer, R. A. (2008) Atomic models of de novo designed cc beta-Met amyloid-like fibrils. Journal of Molecular Biology 376, 898-912. http://www.ncbi.nlm.nih.gov/pubmed/18178219.
Varco-Merth, B., Fromme, R., Wang, M., and Fromme, P. (2008) Crystallization of the c14-rotor of the chloroplast ATP synthase reveals that it contains pigments. Biochimica Et Biophysica Acta 1777, 605-612. http://www.ncbi.nlm.nih.gov/pubmed/18515064.
2007
Beitlich, T., Kühnel, K., Schulze-Briese, C., Shoeman, R. L., and Schlichting, I. (2007) Cryoradiolytic reduction of crystalline heme proteins: analysis by UV-Vis spectroscopy and X-ray crystallography. Journal of Synchrotron Radiation 14, 11-23. http://www.ncbi.nlm.nih.gov/pubmed/17211068.Coulibaly, F., Chiu, E., Ikeda, K., Gutmann, S., Haebel, P. W., Schulze-Briese, C., Mori, H., and Metcalf, P. (2007) The molecular organization of cypovirus polyhedra. Nature 446, 97-101. http://www.ncbi.nlm.nih.gov/pubmed/17330045.
Dhagat, U., Carbone, V., Chung, R. P.-T., Schulze-Briese, C., Endo, S., Hara, A., and El-Kabbani, O. (2007) Structure of 3(17)alpha-hydroxysteroid dehydrogenase (AUTHOR_WWW/SLS/PXI.AKR1C21) holoenzyme from an orthorhombic crystal form: an insight into the bifunctionality of the enzyme. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications 63, 825-830. http://www.ncbi.nlm.nih.gov/pubmed/17909281.
Diez, J., Wang, M., Pohl, E., Tomizaki, T., Bertrand, A., Chen, Q., Dietrich, P., Ingold, G., Knecht, M., Meents, A., Olieric, V., Panepucci, E., Pauluhn, A., Pradervand, C., Roccamante, M., Schneider, R., Walthert, I., Zimoch, E., Schulze-Briese, C. (2007). Industrial use of the SLS-PX MX beamlines, Synchrotron Radiation News, 20, Issue 4, 19-22.
Lucarelli, D., Russo, S, Garman, E., Milano, A., Meyer-Klaucke, W., and Pohl, E. (2007) Crystal structure and function of the zinc uptake regulator AUTHOR_WWW/SLS/PXI.FurB from Mycobacterium tuberculosis. The Journal of Biological Chemistry 282, 9914-22. http://www.ncbi.nlm.nih.gov/pubmed/17213192.
Lupo, D., Li, X.-D., Durand, A., Tomizaki, T., Cherif-Zahar, B., Matassi, G., Merrick, M., and Winkler, F. K. (2007) The 1.3-A resolution structure of Nitrosomonas europaea Rh50 and mechanistic implications for NH3 transport by Rhesus family proteins. Proceedings of the National Academy of Sciences of the United States of America 104, 19303-19308. http://www.ncbi.nlm.nih.gov/pubmed/18032606.
Malo, G. D., Pouwels, L. J., Wang, M., Weichsel, A., Montfort, W. R., Rizzo, M. A., Piston, D. W., and Wachter, R. M. (2007) X-ray structure of Cerulean GFP: a tryptophan-based chromophore useful for fluorescence lifetime imaging. Biochemistry 46, 9865-9873. http://www.ncbi.nlm.nih.gov/pubmed/17685554.
Meents, A., Wagner, A., Schneider, R., Pradervand, C., Pohl, E., and Schulze-Briese, C. (2007) Reduction of X-ray-induced radiation damage of macromolecular crystals by data collection at 15 K: a systematic study. Acta crystallographica. Section D, Biological crystallography 63, 302-9. http://www.ncbi.nlm.nih.gov/pubmed/17327667.
Oliéric, V., Ennifar, E., Meents, A., Fleurant, M., Besnard, C., Pattison, P., Schiltz, M., Schulze-Briese, C., and Dumas, P. (2007) Using X-ray absorption spectra to monitor specific radiation damage to anomalously scattering atoms in macromolecular crystallography. Acta Crystallographica. Section D, Biological crystallography 63, 759-68. http://www.ncbi.nlm.nih.gov/pubmed/17582167.
Smith, M. D., Rosenow, M. A.,* Wang, M.*, Allen, J. P., Szostak, J. W., and Chaput, J. C. (2007) Structural insights into the evolution of a non-biological protein: importance of surface residues in protein fold optimization. PloS One 2, e467. http://www.ncbi.nlm.nih.gov/pubmed/17520026.
2006
Broennimann, C., Eikenberry, E. F., Henrich, B., Horisberger, R., Huelsen, G., Pohl, E., Schmitt, B., Schulze-Briese, C., Suzuki, M., Tomizaki, T., Toyokawa, H., and Wagner, A. (2006) The PILATUS 1M detector. Journal of Synchrotron Radiation 13, 120-130. http://www.ncbi.nlm.nih.gov/pubmed/16495612.Koch, M., Diez, J., and Fritz, G. (2006) Purification and crystallization of the human EF-hand tumour suppressor protein S100A2. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications 62, 1120-1123. http://www.ncbi.nlm.nih.gov/pubmed/17077493.
Salom, D., Le Trong, I., Pohl, E., Ballesteros, J. A., Stenkamp, R. E., Palczewski, K., and Lodowski, D. T. (2006) Improvements in G protein-coupled receptor purification yield light stable rhodopsin crystals. Journal of Structural Biology 156, 497-504. http://www.ncbi.nlm.nih.gov/pubmed/16837211.
Tao, M., Türk, K., Diez, J., Grütter, M. G., Fritz, G., and Steuber, J. (2006) Crystallization of the NADH-oxidizing domain of the Na+-translocating NADH:ubiquinone oxidoreductase from Vibrio cholerae. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications 62, 110-112. http://www.ncbi.nlm.nih.gov/pubmed/16511277.
Wagner, A., Pieren, M., Schulze-Briese, C., Ballmer-Hofer, K., and Prota, A. E. (2006) Structure determination of VEGF-E by sulfur SAD. Acta Crystallographica. Section D, Biological crystallography 62, 1430-4. http://www.ncbi.nlm.nih.gov/pubmed/17057349.
2005
Bunk, O., Pfeiffer, Franz, Stampanoni, M., Patterson, B. D., Schulze-Briese, C., and David, Christian (2005) X-ray beam-position monitoring in the sub-micrometre and sub-second regime. Journal of Synchrotron Radiation 12, 795-799. http://www.ncbi.nlm.nih.gov/pubmed/16239750.El-Kabbani, O., Carbone, V., Darmanin, C., Oka, M., Mitschler, A., Podjarny, A., Schulze-Briese, C., and Chung, R. P.-T. (2005) Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity. Journal of Medicinal Chemistry 48, 5536-5542. http://www.ncbi.nlm.nih.gov/pubmed/16107153.
El-Kabbani, O., Ishikura, S., Wagner, A., Schulze-Briese, C., and Hara, A. (2005) Crystallization and preliminary X-ray diffraction analysis of mouse 3(17)alpha-hydroxysteroid dehydrogenase. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications 61, 688-690. http://www.ncbi.nlm.nih.gov/pubmed/16511129.
Jenner, L., Romby, P., Rees, B., Schulze-Briese, C., Springer, M., Ehresmann, C., Ehresmann, B., Moras, D., and Yusupova, G. (2005) Translational Operator of mRNA on the Ribosome : How Repressor Proteins Exclude Ribosome Binding. Science, 120-123.
Pfeiffer, F., Bunk, O., Schulze-Briese, C., Diaz, A., Weitkamp, T., David, C., van der Veen, J. F., Vartanyants, I., and Robinson, I. K. (2005) Shearing interferometer for quantifying the coherence of hard x-ray beams. Physical Review Letters 94, 164801. http://www.ncbi.nlm.nih.gov/pubmed/15904233.
Wagner, A., Tomizaki, T., and Oetiker, M. (2005) Beam-size effects in radiation damage in insulin and thaumatin crystals. Insulin, 261-267.
2004
Birck, C., Cha, J. Y., Cross, J., Schulze-Briese, C., Meroueh, S. O., Schlegel, H. B., Mobashery, S., and Samama, J.-P. (2004) X-ray crystal structure of the acylated beta-lactam sensor domain of AUTHOR_WWW/SLS/PXI.BlaR1 from Staphylococcus aureus and the mechanism of receptor activation for signal transduction. Journal of the American Chemical Society 126, 13945-13947. http://www.ncbi.nlm.nih.gov/pubmed/15506754.Birck, C., Damian, L., Marty-Detraves, C., Lougarre, A., Schulze-Briese, C., Koehl, P., Fournier, D., Paquereau, L., and Samama, J.-P. (2004) A new lectin family with structure similarity to actinoporins revealed by the crystal structure of Xerocomus chrysenteron lectin XCL. Journal of Molecular Biology 344, 1409-1420. http://www.ncbi.nlm.nih.gov/pubmed/15561152.
Burnouf, D. Y., Olieric, V., Wagner, J., Fujii, S., Reinbolt, J., Fuchs, R. P. P., and Dumas, P. (2004) Structural and biochemical analysis of sliding clamp/ligand interactions suggest a competition between replicative and translesion DNA polymerases. Journal of Molecular Biology 335, 1187-1197. http://linkinghub.elsevier.com/retrieve/pii/S0022283603014736.
El-Kabbani, O., Darmanin, C., Oka, M., Schulze-Briese, C., Tomizaki, T., Hazemann, I., Mitschler, A., and Podjarny, A. (2004) High-resolution structures of human aldose reductase holoenzyme in complex with stereoisomers of the potent inhibitor Fidarestat: stereospecific interaction between the enzyme and a cyclic imide type inhibitor. Journal of Medicinal Chemistry 47, 4530-4537. http://www.ncbi.nlm.nih.gov/pubmed/15317464.
El-Kabbani, O., Darmanin, C., Schneider, T. R., Hazemann, I., Ruiz, F., Oka, M., Joachimiak, A., Schulze-Briese, C., Tomizaki, T., Mitschler, A., and Podjarny, A. (2004) Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with Fidarestat and Minalrestat: implications for the binding of cyclic imide inhibitors. Proteins 55, 805-813. http://www.ncbi.nlm.nih.gov/pubmed/15146479.
2003
Meier, R., Tomizaki, T., Schulze-Briese, C., Baumann, U., and Stocker, A. (2003) The molecular basis of vitamin E retention: structure of human alpha-tocopherol transfer protein. Journal of Molecular Biology 331, 725-734. http://www.ncbi.nlm.nih.gov/pubmed/12899840.2002
Stocker, A., Tomizaki, T., Schulze-Briese, C., and Baumann, U. (2002) Crystal structure of the human supernatant protein factor. Structure (London, England: 1993) 10, 1533-1540. http://www.ncbi.nlm.nih.gov/pubmed/12429094.2000
Brönnimann, C., Florin, S., Lindner, M., Schmitt, B., and Schulze-Briese, C. (2000) Synchrotron beam test with a photon-counting pixel detector. Journal of Synchrotron Radiation 7, 301-306. http://www.ncbi.nlm.nih.gov/pubmed/16609212.Suortti, P., Fiedler, S., Bravin, A., Brochard, T., Mattenet, M., Renier, M., Spanne, P., Thomlinson, W., Charvet, A. M., Elleaume, H., Schulze-Briese, C., and Thompson, A. C. (2000) Fixed-exit monochromator for computed tomography with synchrotron radiation at energies 18-90 keV. Journal of Synchrotron Radiation 7, 340-347. http://www.ncbi.nlm.nih.gov/pubmed/16609218.