PXI

Publications

X06SA PDB Structure Gallery from BioSync

PDB structures measured at X06SA

PXI Publications

2012

  • Structural insights into the neutralization mechanism of a higher primate antibody against dengue virus Cockburn JJB, Sanchez MEN, Goncalvez AP, Zaitseva E, Stura EA, Kikuti CM, Duquerroy S, Dussart P, Chernomordik LV, Lai CJ, Rey FA
    EMBO JOURNAL 31, 767 (2012).
    DOI: 10.1038/emboj.2011.439
  • Mechanism of Dengue Virus Broad Cross-Neutralization by a Monoclonal Antibody Cockburn JJB, Sanchez MEN, Fretes N, Urvoas A, Staropoli I, Kikuti CM, Coffey LL, Seisdedos FA, Bedouelle H, Rey FA
    STRUCTURE 20, 303 (2012).
    DOI: 10.1016/j.str.2012.01.001
  • Contractile Tail Machines of Bacteriophages Leiman PG, Shneider MM
    VIRAL MOLECULAR MACHINES 726, 93 (2012).
    DOI: 10.1007/978-1-4614-0980-9_5
  • Phage Pierces the Host Cell Membrane with the Iron-Loaded Spike Browning C, Shneider MM, Bowman VD, Schwarzer D, Leiman PG
    STRUCTURE 20, 326 (2012).
    DOI: 10.1016/j.str.2011.12.009
  • Immuno- and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity Huber EM, Basler M, Schwab R, Heinemeyer W, Kirk CJ, Groettrup M, Groll M
    CELL 148, 727 (2012).
    DOI: 10.1016/j.cell.2011.12.030
  • Hydroxyureas as Noncovalent Proteasome Inhibitors Gallastegui N, Beck P, Arciniega M, Huber R, Hillebrand S, Groll M
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 51, 247 (2012).
    DOI: 10.1002/anie.201106010
  • A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency. Chodorge M, Zueger S, Stirnimann C, Briand C, Jermutus L, Gruetter MG, Minter RR
    CELL DEATH AND DIFFERENTIATION 1, 1-9 (2012).
    DOI: 10.1038/cdd.2011.208
  • Optimal fine ϕ-slicing for single-photon-counting pixel detectors. Mueller M, Wang M, Schulze-Briese C
    ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 68, 42 (2012).
  • Ethionamide Boosters. 2. Combining Bioisosteric Replacement and Structure-Based Drug Design To Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors Flipo M, Desroses M, Lecat-Guillet N, Villemagne B, Blondiaux N, Leroux F, Piveteau C, Mathys V, Flament MP, Siepmann J, Villeret V, Wohlkoenig A, Wintjens R, Soror SH, Christophe T, Jeon HK, Locht C, Brodin P, Deprez B, Baulard AR, Willand N
    JOURNAL OF MEDICINAL CHEMISTRY 55, 55 (2012).
    DOI: 10.1021/jm200825u
  • ATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complex Moeckel C, Lammens K, Schele A, Hopfner KP
    NUCLEIC ACIDS RESEARCH 40(2), 914-927 (2012).
  • Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II Deupi X, Edwards P, Singhal A, Nickle B, Oprian D, Schertler G, Standfuss J
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109, 119 (2012).
    DOI: 10.1073/pnas.1114089108
  • Molecular Insights into Human Monoamine Oxidase B Inhibition by the Glitazone Antidiabetes Drugs Binda C, Aldeco M, Geldenhuys WJ, Tortorici M, Mattevi A, Edmondson DE
    ACS MEDICINAL CHEMISTRY LETTERS 3, 39 (2012).
    DOI: 10.1021/ml200196p
  • Challenges of sulfur SAD phasing as a routine method in macromolecular crystallography Doutch J, Hough MA, Hasnain SS, Strange RW
    JOURNAL OF SYNCHROTRON RADIATION 19, 19 (2012).

2011

  • Development of a fast read-out system of a single photon counting detector for mammography with synchrotron radiation Lopez FC, Rigon L, Longo R, Arfelli F, Bergamaschi A, Chen RC, Dreossi D, Schmitt B, Vallazza E, Castelli E
    JOURNAL OF INSTRUMENTATION 6, C12031 (2011).
    DOI: 10.1088/1748-0221/6/12/C12031
  • Virtual screening for the discovery of authentic inhibitors against cytosolic 5 '-nucleotidase II: therapeutic use and benefit in cancer treatment Marton Z, Rhimi M, Lallemand P, Jordheim LP, Dumontet C, Aghajari N, Lionne C, Peyrottes S, Chaloin L
    EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 40, 41 (2011).
  • Supramolecular stabilization of acid tolerant L-arabinose isomerase from Lactobacillus sakei Jebors S, Tauran Y, Aghajari N, Boudebbouze S, Maguin E, Haser R, Coleman AW, Rhimi M
    CHEMICAL COMMUNICATIONS 47, 12307 (2011).
    DOI: 10.1039/c1cc14930j
  • The acid-tolerant L-arabinose isomerase from the mesophilic Shewanella sp ANA-3 is highly active at low temperatures Rhimi M, Bajic G, Ilhammami R, Boudebbouze S, Maguin E, Haser R, Aghajari N
    MICROBIAL CELL FACTORIES 10, 96 (2011).
    DOI: 10.1186/1475-2859-10-96
  • Structuring Detergents for Extracting and Stabilizing Functional Membrane Proteins Matar-Merheb R, Rhimi M, Leydier A, Huche F, Galian C, Desuzinges-Mandon E, Ficheux D, Flot D, Aghajari N, Kahn R, Di Pietro A, Jault JM, Coleman AW, Falson P
    PLOS ONE 6, e18036 (2011).
    DOI: 10.1371/journal.pone.0018036
  • A Crystal Structure of the Catalytic Core Domain of an Avian Sarcoma and Leukemia Virus Integrase Suggests an Alternate Dimeric Assembly Ballandras A, Moreau K, Robert X, Confort MP, Merceron R, Haser R, Ronfort C, Gouet P
    PLOS ONE 6, e23032 (2011).
    DOI: 10.1371/journal.pone.0023032
  • Functional analyses of mutants of the central core domain of an Avian Sarcoma/Leukemia Virus integrase Charmetant J, Moreau K, Gallay K, Ballandras A, Gouet P, Ronfort C
    VIROLOGY 421, 42 (2011).
    DOI: 10.1016/j.virol.2011.09.008
  • Mechanism of USP7/HAUSP Activation by Its C-Terminal Ubiquitin-like Domain and Allosteric Regulation by GMP-Synthetase Faesen AC, Dirac AMG, Shanmugham A, Ovaa H, Perrakis A, Sixma TK
    MOLECULAR CELL 44, 147 (2011).
    DOI: 10.1016/j.molcel.2011.06.034
  • Target highlights in CASP9: Experimental target structures for the critical assessment of techniques for protein structure prediction Kryshtafovych A, Moult J, Bartual SG, Bazan JF, Berman H, Casteel DE, Christodoulou E, Everett JK, Hausmann J, Heidebrecht T, Hills T, Hui R, Hunt JF, Seetharaman J, Joachimiak A, Kennedy MA, Kim C, Lingel A, Michalska K, Montelione GT, Otero JM, Perrakis A, Pizarro JC, van Raaij MJ, Ramelot TA, Rousseau F, Tong L, Wernimont AK, Young J, Schwede T
    PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 79, 6 (2011).
    DOI: 10.1002/prot.23196
  • PLP-dependent enzymes as entry and exit gates of sphingolipid metabolism Bourquin F, Capitani G, Grutter MG
    PROTEIN SCIENCE 20, 1492 (2011).
    DOI: 10.1002/pro.679
  • Crystal structure of 6-SST/6-SFT from Pachysandra terminalis, a plant fructan biosynthesizing enzyme in complex with its acceptor substrate 6-kestose Lammens W, Le Roy K, Yuan S, Vergauwen R, Rabijns A, Van Laere A, Strelkov SV, Van den Ende W
    PLANT JOURNAL 0, 0 (2011).
    DOI: 10.1111/j.1365-313X.2011.04858.x
  • Allosteric antibody inhibition of human Hepsin protease Koschubs T, Dengl S, Duerr H, Kaluza K, Georges G, Hartl C, Jennewein S, Lanzendoerfer M, Auer J, Stern A, Huang KS, Packman K, Gubler U, Kostrewa D, Ries S, Hansen S, Kohnert U, Cramer P, Mundigl O
    BIOCHEMICAL JOURNAL 0, 0 (2011).
    DOI: 10.1042/BJ20111317
  • Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor Koeberle SC, Romir J, Fischer S, Koeberle A, Schattel V, Albrecht W, Grutter C, Werz O, Rauh D, Stehle T, Laufer SA
    NATURE CHEMICAL BIOLOGY 8, 141 (2011).
    DOI: 10.1038/nchembio.761
  • Unraveling the Perplexing Structure of the Zeolite SSZ-57 Baerlocher C, Weber T, McCusker LB, Palatinus L, Zones SI
    SCIENCE 333, 1134 (2011).
    DOI: 10.1126/science.1207466
  • Crystal structure of the intraflagellar transport complex 25/27 Bhogaraju S, Taschner M, Morawetz M, Basquin C, Lorentzen E
    EMBO JOURNAL 30, 1907 (2011).
    DOI: 10.1038/emboj.2011.110
  • Substrate-induced remodeling of the active site regulates human HTRA1 activity Truebestein L, Tennstaedt A, Moonig T, Krojer T, Canellas F, Kaiser M, Clausen T, Ehrmann M
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 18, 386 (2011).
    DOI: 10.1038/nsmb.2013
  • Crystal Structure of Inulosucrase from Lactobacillus: Insights into the Substrate Specificity and Product Specificity of GH68 Fructansucrases Pijning T, Anwar MA, Boger M, Dobruchowska JM, Leemhuis H, Kralj S, Dijkhuizen L, Dijkstra BW
    JOURNAL OF MOLECULAR BIOLOGY 412, 80 (2011).
    DOI: 10.1016/j.jmb.2011.07.031
  • CH5424802, a Selective ALK Inhibitor Capable of Blocking the Resistant Gatekeeper Mutant Sakamoto H, Tsukaguchi T, Hiroshima S, Kodama T, Kobayashi T, Fukami TA, Oikawa N, Tsukuda T, Ishii N, Aoki Y
    CANCER CELL 19, 679 (2011).
    DOI: 10.1016/j.ccr.2011.04.004
  • Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit Belousoff MJ, Shapira T, Bashan A, Zimmerman E, Rozenberg H, Arakawa K, Kinashi H, Yonath A
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 108, 2717 (2011).
    DOI: 10.1073/pnas.1019406108
  • The Structure of CDK8/CycC Implicates Specificity in the CDK/Cyclin Family and Reveals Interaction with a Deep Pocket Binder Schneider EV, Bottcher J, Blaesse M, Neumann L, Huber R, Maskos K
    JOURNAL OF MOLECULAR BIOLOGY 412, 251 (2011).
    DOI: 10.1016/j.jmb.2011.07.020
  • Phthalazinone Pyrazoles as Potent, Selective, and Orally Bioavailable Inhibitors of Aurora-A Kinase Prime ME, Courtney SM, Brookfield FA, Marston RW, Walker V, Warne J, Boyd AE, Kairies NA, von der Saal W, Limberg A, Georges G, Engh RA, Goller B, Rueger P, Rueth M
    JOURNAL OF MEDICINAL CHEMISTRY 54, 312 (2011).
  • The Structure of the Kinesin-1 Motor-Tail Complex Reveals the Mechanism of Autoinhibition Kaan HYK, Hackney DD, Kozielski F
    SCIENCE 333, 883 (2011).
    DOI: 10.1126/science.1204824
  • Structural basis for the cyclophilin A binding affinity and immunosuppressive potency of E-ISA247 (voclosporin) Kuglstatter A, Mueller F, Kusznir E, Gsell B, Stihle M, Thoma R, Benz J, Aspeslet L, Freitag D, Hennig M
    ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 67, 119 (2011).
    DOI: 10.1107/S0907444910051905
  • Learning from Directed Evolution: Thermus aquaticus DNA Polymerase Mutants with Translesion Synthesis Activity Obeid S, Schnur A, Gloeckner C, Blatter N, Welte W, Diederichs K, Marx A
    CHEMBIOCHEM 12, 1574 (2011).
    DOI: 10.1002/cbic.201000783
  • Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers Gerritz SW, Cianci C, Kim S, Pearce BC, Deminie C, Discotto L, McAuliffe B, Minassian BF, Shi SH, Zhu SR, Zhai WX, Pendri A, Li G, Poss MA, Edavettal S, McDonnell PA, Lewis HA, Maskos K, Mortl M, Kiefersauer R, Steinbacher S, Baldwin ET, Metzler W, Bryson J, Healy MD, Philip T, Zoeckler M, Schartman R, Sinz M, Leyva-Grado VH, Hoffmann HH, Langley DR, Meanwell NA, Krystal M
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 108, 15366 (2011).
    DOI: 10.1073/pnas.1107906108
  • A Conformational Switch Underlies ClpP Protease Function Geiger SR, Bottcher T, Sieber SA, Cramer P
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 50, 5748 (2011).
    DOI: 10.1002/anie.201100666
  • Peptides Targeting the PDZ Domain of PTPN4 Are Efficient Inducers of Glioblastoma Cell Death Babault N, Cordier F, Lafage M, Cockburn J, Haouz A, Prehaud C, Rey FA, Delepierre M, Buc H, Lafon M, Wolff N
    STRUCTURE 19, 1518 (2011).
    DOI: 10.1016/j.str.2011.07.007
  • Ethionamide Boosters: Synthesis, Biological Activity, and Structure-Activity Relationships of a Series of 1,2,4-Oxadiazole EthR Inhibitors Flipo M, Desroses M, Lecat-Guillet N, Dirie B, Carette X, Leroux F, Piveteau C, Demirkaya F, Lens Z, Rucktooa P, Villeret V, Christophe T, Jeon HK, Locht C, Brodin P, Deprez B, Baulard AR, Willand N
    JOURNAL OF MEDICINAL CHEMISTRY 54, 2994 (2011).
    DOI: 10.1021/jm200076a
  • Carbon monoxide poisoning is prevented by the energy costs of conformational changes in gas-binding haemproteins Antonyuk SV, Rustage N, Petersen CA, Arnst JL, Heyes DJ, Sharma R, Berry NG, Scrutton NS, Eady RR, Andrew CR, Hasnain SS
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 108, 15780 (2011).
    DOI: 10.1073/pnas.1109051108
  • Optimization of a novel class of benzimidazole-based farnesoid X receptor (FXR) agonists to improve physicochemical and ADME properties Richter HGF, Benson GM, Bleicher KH, Blum D, Chaput E, Clemann N, Feng S, Gardes C, Grether U, Hartman P, Kuhn B, Martin RE, Plancher JM, Rudolph MG, Schuler F, Taylor S
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 21, 1134 (2011).
    DOI: 10.1016/j.bmcl.2010.12.123
  • Crystal structure of the EphA4 protein tyrosine kinase domain in the apo- and dasatinib-bound state Farenc C, Celie PHN, Tensen CP, de Esch IJP, Siegal G
    FEBS LETTERS 585, 3593 (2011).
    DOI: 10.1016/j.febslet.2011.10.028
  • An Old NSAID Revisited: Crystal Structure of Aldose Reductase in Complex with Sulindac at 1.0 angstrom Supports a Novel Mechanism for its Anticancer and Antiproliferative Effects Steuber H
    CHEMMEDCHEM 6, 2155 (2011).
    DOI: 10.1002/cmdc.201100374
  • Structural Basis for the Allosteric Regulation and Substrate Recognition of Human Cytosolic 5 '-Nucleotidase II Wallden K, Nordlund P
    JOURNAL OF MOLECULAR BIOLOGY 408, 684 (2011).
    DOI: 10.1016/j.jmb.2011.02.059
  • Atomic Structures Suggest Determinants of Transmission Barriers in Mammalian Prion Disease Apostol MI, Wiltzius JJW, Sawaya MR, Cascio D, Eisenberg D
    BIOCHEMISTRY 50, 2456 (2011).
    DOI: 10.1021/bi101803k
  • The Refined Structure of Functional Unit h of Keyhole Limpet Hemocyanin (KLH1-h) Reveals Disulfide Bridges Jaenicke E, Buchler K, Decker H, Markl J, Schroder GF
    IUBMB LIFE 63, 183 (2011).
    DOI: 10.1002/iub.435
  • Inhibitors of the Herbicidal Target IspD: Allosteric Site Binding Witschel MC, Hoffken HW, Seet M, Parra L, Mietzner T, Thater F, Niggeweg R, Rohl F, Illarionov B, Rohdich F, Kaiser J, Fischer M, Bacher A, Diederich F
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 50, 7931 (2011).
    DOI: 10.1002/anie.201102281
  • Dual Chaperone Role of the C-Terminal Propeptide in Folding and Oligomerization of the Pore-Forming Toxin Aerolysin Iacovache I, Degiacomi MT, Pernot L, Ho S, Schiltz M, Dal Peraro M, van der Goot FG
    PLOS PATHOGENS 7, e1002135 (2011).
    DOI: 10.1371/journal.ppat.1002135
  • Crystal Structures of T. b. rhodesiense Adenosine Kinase Complexed with Inhibitor and Activator: Implications for Catalysis and Hyperactivation Kuettel S, Greenwald J, Kostrewa D, Ahmed S, Scapozza L, Perozzo R
    PLOS NEGLECTED TROPICAL DISEASES 5, e1164 (2011).
    DOI: 10.1371/journal.pntd.0001164
  • Synthesis, Crystal Structure, and in Vitro Biological Evaluation of C-6 Pyrimidine Derivatives: New Lead Structures for Monitoring Gene Expression in Vivo Martic M, Pernot L, Westermaier Y, Perozzo R, Kraljevic TG, Kristafor S, Raic-Malic S, Scapozza L, Ametamey S
    NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS 30, 293 (2011).
    DOI: 10.1080/15257770.2011.581258
  • Simultaneous Formation of Right- and Left-handed Anti-parallel Coiled-coil Interfaces by a Coil2 Fragment of Human Lamin A Kapinos LE, Burkhard P, Herrmann H, Aebi U, Strelkov SV
    JOURNAL OF MOLECULAR BIOLOGY 408, 135 (2011).
    DOI: 10.1016/j.jmb.2011.02.037
  • In silico identification and crystal structure validation of caspase-3 inhibitors without a P1 aspartic acid moiety Ganesan R, Jelakovic S, Mittl PRE, Caflisch A, Grutter MG
    ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS 67, 842 (2011).
    DOI: 10.1107/S1744309111018604
  • Combining in-situ proteolysis and microseed matrix screening to promote crystallization of PrPc-nanobody complexes Abskharon RNN, Soror SH, Pardon E, El Hassan H, Legname G, Steyaert J, Wohlkonig A
    PROTEIN ENGINEERING DESIGN & SELECTION 24, 737 (2011).
    DOI: 10.1093/protein/gzr017
  • Structure-Based Redesign of Cofactor Binding in Putrescine Oxidase Kopacz MM, Rovida S, van Duijn E, Fraaije MW, Mattevi A
    BIOCHEMISTRY 50, 4209 (2011).
    DOI: 10.1021/bi200372u
  • Crystal Structure of Reovirus Attachment Protein sigma 1 in Complex with Sialylated Oligosaccharides Reiter DM, Frierson JM, Halvorson EE, Kobayashi T, Dermody TS, Stehle T
    PLOS PATHOGENS 7, e1002166 (2011).
    DOI: 10.1371/journal.ppat.1002166
  • Fragment Growing Induces Conformational Changes in Acetylcholine-Binding Protein: A Structural and Thermodynamic Analysis Edink E, Rucktooa P, Retra K, Akdemir A, Nahar T, Zuiderveld O, van Elk R, Janssen E, van Nierop P, van Muijlwijk-Koezen J, Smit AB, Sixma TK, Leurs R, de Esch IJP
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 133, 5363 (2011).
    DOI: 10.1021/ja110571r
  • Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures to identify structurally novel ligands for the nicotinic receptors Akdemir A, Rucktooa P, Jongejan A, van Elk R, Bertrand S, Sixma TK, Bertrand D, Smit AB, Leurs R, de Graaf C, de Esch IJP
    BIOORGANIC & MEDICINAL CHEMISTRY 19, 6107 (2011).
    DOI: 10.1016/j.bmc.2011.08.028
  • The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1 Heidebrecht T, Christodoulou E, Chalmers MJ, Jan S, Ter Riet B, Grover RK, Joosten RP, Littler D, van Luenen H, Griffin PR, Wentworth P, Borst P, Perrakis A
    NUCLEIC ACIDS RESEARCH 39, 5715 (2011).
    DOI: 10.1093/nar/gkr125
  • Molecular basis of substrate-induced permeation by an amino acid antiporter Kowalczyk L, Ratera M, Paladino A, Bartoccioni P, Errasti-Murugarren E, Valencia E, Portella G, Bial S, Zorzano A, Fita I, Orozco M, Carpena X, Vazquez-Ibar JL, Palacin M
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 108, 3935 (2011).
    DOI: 10.1073/pnas.1018081108
  • Crystal structure of the hybrid state of ribosome in complex with the guanosine triphosphatase release factor 3 Jin H, Kelley AC, Ramakrishnan V
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 108, 15798 (2011).
    DOI: 10.1073/pnas.1112185108
  • Membrane Remodeling by the Double-Barrel Scaffolding Protein of Poxvirus Hyun JK, Accurso C, Hijnen M, Schult P, Pettikiriarachchi A, Mitra AK, Coulibaly F
    PLOS PATHOGENS 7, e1002239 (2011).
    DOI: 10.1371/journal.ppat.1002239
  • Structure and mechanism of the chromatin remodelling factor ISW1a Yamada K, Frouws TD, Angst B, Fitzgerald DJ, DeLuca C, Schimmele K, Sargent DF, Richmond TJ
    NATURE 472, 448 (2011).
    DOI: 10.1038/nature09947
  • Proteasome structure, function, and lessons learned from beta-lactone inhibitors Potts B, Groll M
    CURRENT TOPICS IN MEDICINAL CHEMISTRY 11, 2850 (2011).
  • Marizomib, a Proteasome Inhibitor for All Seasons: Preclinical Profile and a Framework for Clinical Trials Potts BC, Albitar MX, Anderson KC, Baritaki S, Berkers C, Bonavida B, Chandra J, Chauhan D, Cusack JC, Fenical W, Ghobrial IM, Groll M, Jensen PR, Lam KS, Lloyd GK, McBride W, McConkey DJ, Miller CP, Neuteboom STC, Oki Y, Ovaa H, Pajonk F, Richardson PG, Roccaro AM, Sloss CM, Spear MA, Valashi E, Younes A, Palladino MA
    CURRENT CANCER DRUG TARGETS 11, 254 (2011).
  • Biochemistry of the non-mevalonate isoprenoid pathway Grawert T, Groll M, Rohdich F, Bacher A, Eisenreich W
    CELLULAR AND MOLECULAR LIFE SCIENCES 68, 3797 (2011).
    DOI: 10.1007/s00018-011-0753-z
  • Reverse Fosmidomycin Derivatives against the Antimalarial Drug Target IspC (Dxr) Behrendt CT, Kunfermann A, Illarionova V, Matheeussen A, Pein MK, Grawert T, Kaiser J, Bacher A, Eisenreich W, Illarionov B, Fischer M, Maes L, Groll M, Kurz T
    JOURNAL OF MEDICINAL CHEMISTRY 54, 6796 (2011).
    DOI: 10.1021/jm200694q
  • Structural basis of RNA polymerase II backtracking, arrest and reactivation Cheung ACM, Cramer P
    NATURE 471, 249 (2011).
    DOI: 10.1038/nature09785
  • Mediator head subcomplex Med11/22 contains a common helix bundle building block with a specific function in transcription initiation complex stabilization Seizl M, Lariviere L, Pfaffeneder T, Wenzeck L, Cramer P
    NUCLEIC ACIDS RESEARCH 39, 6291 (2011).
    DOI: 10.1093/nar/gkr229
  • Structural basis of initial RNA polymerase II transcription Cheung ACM, Sainsbury S, Cramer P
    EMBO JOURNAL 30, 4755 (2011).
    DOI: 10.1038/emboj.2011.396
  • Human DNA Polymerase beta Mutations Allowing Efficient Abasic Site Bypass Gieseking S, Bergen K, Di Pasquale F, Diederichs K, Welte W, Marx A
    JOURNAL OF BIOLOGICAL CHEMISTRY 286, 4011 (2011).
    DOI: 10.1074/jbc.M110.176826
  • Designed ankyrin repeat protein binders for the crystallization of AcrB: Plasticity of the dominant interface Monroe N, Sennhauser G, Seeger MA, Briand C, Grutter MG
    JOURNAL OF STRUCTURAL BIOLOGY 174, 269 (2011).
    DOI: 10.1016/j.jsb.2011.01.014
  • High-Resolution X-Ray Structure of the Trimeric Scar/WAVE-Complex Precursor Brk1 Linkner J, Witte G, Stradal T, Curth U, Faix J
    PLOS ONE 6, e21327 (2011).
    DOI: 10.1371/journal.pone.0021327
  • Bispecific digoxigenin-binding antibodies for targeted payload delivery Metz S, Haas AK, Daub K, Croasdale R, Stracke J, Lau WM, Georges G, Josel HP, Dziadek S, Hopfner KP, Lammens A, Scheuer W, Hoffmann E, Mundigl O, Brinkmann U
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 108, 8194 (2011).
    DOI: 10.1073/pnas.1018565108
  • Reversible bond formation enables the replication and amplification of a crosslinking salen complex as an orthogonal base pair Kaul C, Muller M, Wagner M, Schneider S, Carell T
    NATURE CHEMISTRY 3, 794 (2011).
    DOI: 10.1038/NCHEM.1117
  • X-ray structure of the arenavirus glycoprotein GP2 in its postfusion hairpin conformation Igonet S, Vaney MC, Vonhrein C, Bricogne G, Stura EA, Hengartner H, Eschli B, Rey FA
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 108, 19967 (2011).
    DOI: 10.1073/pnas.1108910108
  • Crystal Structure of the Eukaryotic 60S Ribosomal Subunit in Complex with Initiation Factor 6 Klinge S, Voigts-Hoffmann F, Leibundgut M, Arpagaus S, Ban N
    SCIENCE 334, 941 (2011).
    DOI: 10.1126/science.1211204
  • Chaperonins: two rings for folding Yebenes H, Mesa P, Munoz IG, Montoya G, Valpuesta JM
    TRENDS IN BIOCHEMICAL SCIENCES 36, 424 (2011).
    DOI: 10.1016/j.tibs.2011.05.003
  • Rational design and synthesis of aminopiperazinones as beta-secretase (BACE) inhibitors Tresadern G, Delgado F, Delgado O, Gijsen H, Macdonald GJ, Moechars D, Rombouts F, Alexander R, Spurlino J, Van Gool M, Vega JA, Trabanco AA
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 21, 7255 (2011).
    DOI: 10.1016/j.bmcl.2011.10.050
  • Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase Du J, Say RF, Lu W, Fuchs G, Einsle O
    NATURE 478, 534 (2011).
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  • The structural basis of agonist-induced activation in constitutively active rhodopsin Standfuss J, Edwards PC, D'Antona A, Fransen M, Xie GF, Oprian DD, Schertler GFX
    NATURE 471, 656 (2011).
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  • The crystal structures of human S100B in the zinc- and calcium-loaded state at three pH values reveal zinc ligand swapping Ostendorp T, Diez J, Heizmann CW, Fritz G
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1813, 1083 (2011).
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  • Distal-to-Proximal NO Conversion in Hemoproteins: The Role of the Proximal Pocket Hough MA, Antonyuk SV, Barbieri S, Rustage N, McKay AL, Servid AE, Eady RR, Andrew CR, Hasnain SS
    JOURNAL OF MOLECULAR BIOLOGY 405, 395 (2011).
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  • Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation Wu B, Davey GE, Nazarov AA, Dyson PJ, Davey CA
    NUCLEIC ACIDS RESEARCH 39, 8200 (2011).
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  • A Ruthenium Antimetastasis Agent Forms Specific Histone Protein Adducts in the Nucleosome Core Wu B, Ong MS, Groessl M, Adhireksan Z, Hartinger CG, Dyson PJ, Davey CA
    CHEMISTRY-A EUROPEAN JOURNAL 17, 3562 (2011).
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  • Nucleosome structural studies Tan S, Davey CA
    CURRENT OPINION IN STRUCTURAL BIOLOGY 21, 128 (2011).
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  • The Structure of the Eukaryotic Ribosome at 3.0 angstrom Resolution Ben-Shem A, de Loubresse NG, Melnikov S, Jenner L, Yusupova G, Yusupov M
    SCIENCE 334, 1524 (2011).
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  • Structure and DNA-binding activity of the Pyrococcus furiosus SMC protein hinge domain Griese JJ, Hopfner KP
    PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 79, 558 (2011).
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  • Processive RNA decay by the exosome Merits of a quantitative bayesian sampling approach Niederberger T, Hartung S, Hopfner KP, Tresch A
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  • Structural biochemistry of nuclear actin-related proteins 4 and 8 reveals their interaction with actin Fenn S, Breitsprecher D, Gerhold CB, Witte G, Faix J, Hopfner KP
    EMBO JOURNAL 30, 2153 (2011).
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  • Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for type I/II distinction of CD20 antibodies Niederfellner G, Lammens A, Mundigl O, Georges GJ, Schaefer W, Schwaiger M, Franke A, Wiechmann K, Jenewein S, Slootstra JW, Timmerman P, Brannstrom A, Lindstrom F, Mossner E, Umana P, Hopfner KP, Klein C
    BLOOD 118, 358 (2011).
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  • Structure and mechanism of the Swi2/Snf2 remodeller Mot1 in complex with its substrate TBP Wollmann P, Cui S, Viswanathan R, Berninghausen O, Wells MN, Moldt M, Witte G, Butryn A, Wendler P, Beckmann R, Auble DT, Hopfner KP
    NATURE 475, 403 (2011).
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  • The Mre11:Rad50 Structure Shows an ATP-Dependent Molecular Clamp in DNA Double-Strand Break Repair Lammens K, Bemeleit DJ, Mockel C, Clausing E, Schele A, Hartung S, Schiller CB, Lucas M, Angermuller C, Soding J, Strasser K, Hopfner KP
    CELL 145, 54 (2011).
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  • The RIG-I ATPase domain structure reveals insights into ATP-dependent antiviral signalling Civril F, Bennett M, Moldt M, Deimling T, Witte G, Schiesser S, Carell T, Hopfner KP
    EMBO REPORTS 12, 1127 (2011).
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  • Ligand Activation of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC Zimmermann I, Dutzler R
    PLOS BIOLOGY 9, e1001101 (2011).
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  • Automatic loop centring with a high-precision goniometer head at the SLS macromolecular crystallography beamlines Pauluhn A, Pradervand C, Rossetti D, Salathe M, Schulze-Briese C
    JOURNAL OF SYNCHROTRON RADIATION 18, 595 (2011).
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  • Radiation damage in room-temperature data acquisition with the PILATUS 6M pixel detector Rajendran C, Dworkowski FSN, Wang MT, Schulze-Briese C
    JOURNAL OF SYNCHROTRON RADIATION 18, 318 (2011).
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  • Crystal structure of the GlnZ-DraG complex reveals a different form of P-II-target interaction Rajendran C, Gerhardt ECM, Bjelic S, Gasperina A, Scarduelli M, Pedrosa FO, Chubatsu LS, Merrick M, Souza EM, Winkler FK, Huergo LF, Li XD
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 108, 18972 (2011).
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  • Structure-Based Design of Short Peptide Ligands Binding onto the E. coli Processivity Ring Wolff P, Olieric V, Briand JP, Chaoin O, Dejaegere A, Dumas P, Ennifar E, Guichard G, Wagner J, Burnouf DY
    JOURNAL OF MEDICINAL CHEMISTRY 54, 4627 (2011).
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  • Beyond single photon counting X-ray detectors Bergamaschi A, Dinapoli R, Henrich B, Johnson I, Mozzanica A, Shi X, Schmitt B
    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT 628, 238 (2011).
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  • EIGER: Next generation single photon counting detector for X-ray applications Dinapoli R, Bergamaschi A, Henrich B, Horisberger R, Johnson I, Mozzanica A, Schmid E, Schmitt B, Schreiber A, Shi XT, Theidel G
    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT 650, 79 (2011).
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  • Evolution of Two Modes of Intrinsic RNA Polymerase Transcript Cleavage Ruan WJ, Lehmann E, Thomm M, Kostrewa D, Cramer P
    JOURNAL OF BIOLOGICAL CHEMISTRY 286, 18701 (2011).
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  • Structure of human mitochondrial RNA polymerase Ringel R, Sologub M, Morozov YI, Litonin D, Cramer P, Temiakov D
    NATURE 478, 269 (2011).
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  • Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth Blattner C, Jennebach S, Herzog F, Mayer A, Cheung ACM, Witte G, Lorenzen K, Hopfner KP, Heck AJR, Aebersold R, Cramer P
    GENES & DEVELOPMENT 25, 2093 (2011).
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  • Architecture of the RNA polymerase-Spt4/5 complex and basis of universal transcription processivity Martinez-Rucobo FW, Sainsbury S, Cheung ACM, Cramer P
    EMBO JOURNAL 30, 1302 (2011).
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  • Structural insights into the extracellular assembly of the hematopoietic Flt3 signaling complex Verstraete K, Vandriessche G, Januar M, Elegheert J, Shkumatov AV, Desfosses A, Van Craenenbroeck K, Svergun DI, Gutsche I, Vergauwen B, Savvides SN
    BLOOD 118, 60 (2011).
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  • Crystal Structures and Repair Studies Reveal the Identity and the Base-Pairing Properties of the UV-Induced Spore Photoproduct DNA Lesion Heil K, Kneuttinger AC, Schneider S, Lischke U, Carell T
    CHEMISTRY-A EUROPEAN JOURNAL 17, 9651 (2011).
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  • A structural overview of the plasma membrane Na+, K+-ATPase and H+-ATPase ion pumps Morth JP, Pedersen BP, Buch-Pedersen MJ, Andersen JP, Vilsen B, Palmgren MG, Nissen P
    NATURE REVIEWS MOLECULAR CELL BIOLOGY 12, 60 (2011).
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  • Structural insights into the high affinity binding of cardiotonic steroids to the Na+,K+-ATPase Yatime L, Laursen M, Morth JP, Esmann M, Nissen P, Fedosova NU
    JOURNAL OF STRUCTURAL BIOLOGY 174, 296 (2011).
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  • Crystallization and preliminary structural analysis of the Listeria monocytogenes Ca2+-ATPase LMCA1 Andersen JL, Gourdon P, Moller JV, Morth JP, Nissen P
    ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS 67, 718 (2011).
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  • HiLiDe-Systematic Approach to Membrane Protein Crystallization in Lipid and Detergent Gourdon P, Andersen JL, Hein KL, Bublitz M, Pedersen BP, Liu XY, Yatime L, Nyblom M, Nielsen TT, Olesen C, Moller JV, Nissen P, Morth JP
    CRYSTAL GROWTH & DESIGN 11, 2098 (2011).
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  • Crystal structure of a copper-transporting PIB-type ATPase Gourdon P, Liu XY, Skjorringe T, Morth JP, Moller LB, Pedersen BP, Nissen P
    NATURE 475, 59 (2011).
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  • Crystal Structure of Plasminogen Activator Inhibitor-1 in an Active Conformation with Normal Thermodynamic Stability Jensen JK, Thompson LC, Bucci JC, Nissen P, Gettins PGW, Peterson CB, Andrease PA, Morth JP
    JOURNAL OF BIOLOGICAL CHEMISTRY 286, 29709 (2011).
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  • Structure of the RACK1 Dimer from Saccharomyces cerevisiae Yatime L, Hein KL, Nilsson J, Nissen P
    JOURNAL OF MOLECULAR BIOLOGY 411, 486 (2011).
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  • Mutual adaptation of a membrane protein and its lipid bilayer during conformational changes Sonntag Y, Musgaard M, Olesen C, Schiott B, Moller JV, Nissen P, Thogersen L
    NATURE COMMUNICATIONS 2, 304 (2011).
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  • The structural basis of modularity in ECF-type ABC transporters Erkens GB, Berntsson RPA, Fulyani F, Majsnerowska M, Vujicic-Zagar A, ter Beek J, Poolman B, Slotboom DJ
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 18, 755 (2011).
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  • N2O binding at a [4Cu:2S] copper-sulphur cluster in nitrous oxide reductase Pomowski A, Zumft WG, Kroneck PMH, Einsle O
    NATURE 477, 234 (2011).
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  • Novel approach to controlled protein crystallization through ligandation of yttrium cations Zhang FJ, Zocher G, Sauter A, Stehle T, Schreiber F
    JOURNAL OF APPLIED CRYSTALLOGRAPHY 44, 755 (2011).
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  • Three-Dimensional Structure of alpha-Crystallin Domain Dimers of Human Small Heat Shock Proteins HSPB1 and HSPB6 Baranova EV, Weeks SD, Beelen S, Bukach OV, Gusev NB, Strelkov SV
    JOURNAL OF MOLECULAR BIOLOGY 411, 110 (2011).
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  • Structure of the membrane domain of respiratory complex I Efremov RG, Sazanov LA
    NATURE 476, 414 (2011).
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  • Quaternary Structure of the Oxaloacetate Decarboxylase Membrane Complex and Mechanistic Relationships to Pyruvate Carboxylases Balsera M, Buey RM, Li XD
    JOURNAL OF BIOLOGICAL CHEMISTRY 286, 9457 (2011).
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  • Structures of the Major Capsid Proteins of the Human Karolinska Institutet and Washington University Polyomaviruses Neu U, Wang JB, Macejak D, Garcea RL, Stehle T
    JOURNAL OF VIROLOGY 85, 7384 (2011).
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  • The crystal structure of yeast CCT reveals intrinsic asymmetry of eukaryotic cytosolic chaperonins. Dekker C, Roe SM, Mccormack EA, Beuron F, Pearl LH, Willison KR
    EMBO JOURNAL 30(15), 3078 (2011).
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  • In Vitro Folding and Assembly of the Escherichia coli ATP-binding Cassette Transporter, BtuCD Di Bartolo ND, Hvorup RN, Locher KP, Booth PJ
    JOURNAL OF BIOLOGICAL CHEMISTRY 286, 18807 (2011).
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  • X-ray structure of a bacterial oligosaccharyltransferase Lizak C, Gerber S, Numao S, Aebi M, Locher KP
    NATURE 474, 350 (2011).
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  • SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase van der Vaart B, Manatschal C, Grigoriev I, Olieric V, Gouveia SM, Bjelic S, Demmers J, Vorobjev I, Hoogenraad CC, Steinmetz MO, Akhmanova A
    JOURNAL OF CELL BIOLOGY 193, 1083 (2011).
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  • Inducible production of recombinant human Flt3 ectodomain variants in mammalian cells and preliminary crystallographic analysis of Flt3 ligand-receptor complexes Verstraete K, Remmerie B, Elegheert J, Lintermans B, Haegeman G, Vanhoenacker P, Van Craenenbroeck K, Savvides SN
    ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS 67, 325 (2011).
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  • Structure of GlnK1, a signalling protein from Archaeoglobus fulgidus Litz C, Helfmann S, Gerhardt S, Andrade SLA
    ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS 67, 178 (2011).
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  • pH-Dependent Gating in a FocA Formate Channel Lu W, Du JA, Wacker T, Gerbig-Smentek E, Andrade SLA, Einsle O
    SCIENCE 332, 352 (2011).
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  • Meganucleases and Other Tools for Targeted Genome Engineering: Perspectives and Challenges for Gene Therapy Silva G, Poirot L, Galetto R, Smith J, Montoya G, Duchateau P, Paques F
    CURRENT GENE THERAPY 11, 11 (2011).
  • Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus Munoz IG, Prieto J, Subramanian S, Coloma J, Redondo P, Villate M, Merino N, Marenchino M, D'Abramo M, Gervasio FL, Grizot S, Daboussi F, Smith J, Chion-Sotinel I, Paques F, Duchateau P, Alibes A, Stricher F, Serrano L, Blanco FJ, Montoya G
    NUCLEIC ACIDS RESEARCH 39, 729 (2011).
    DOI: 10.1093/nar/gkq801
  • Transient DNA/RNA-protein interactions Blanco FJ, Montoya G
    FEBS JOURNAL 278, 1643 (2011).
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  • Structural Basis of the 9-Fold Symmetry of Centrioles Kitagawa D, Vakonakis I, Olieric N, Hilbert M, Keller D, Olieric V, Bortfeld M, Erat MC, Fluckiger I, Gonczy P, Steinmetz MO
    CELL 144, 364 (2011).
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  • Crystal Structure of the Eukaryotic 40S Ribosomal Subunit in Complex with Initiation Factor 1 Rabl J, Leibundgut M, Ataide SF, Haag A, Ban N
    SCIENCE 331, 730 (2011).
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  • Structural basis of substrate discrimination and integrin binding by autotaxin Hausmann J, Kamtekar S, Christodoulou E, Day JE, Wu T, Fulkerson Z, Albers HMHG, van Meeteren LA, Houben AJS, van Zeijl L, Jansen S, Andries M, Hall T, Pegg LE, Benson TE, Kasiem M, Harlos K, Kooi CWV, Smyth SS, Ovaa H, Bollen M, Morris AJ, Moolenaar WH, Perrakis A
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 18, 198 (2011).
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  • Structural determinants of vascular endothelial growth factor-D receptor binding and specificity Leppanen VM, Jeltsch M, Anisimov A, Tvorogov D, Aho K, Kalkkinen N, Toivanen P, Yla-Herttuala S, Ballmer-Hofer K, Alitalo K
    BLOOD 117, 1507 (2011).
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  • Discovery of isoindoline and tetrahydroisoquinoline derivatives as potent, selective PPAR delta agonists Luckhurst CA, Stein LA, Furber M, Webb N, Ratcliffe MJ, Allenby G, Botterell S, Tomlinson W, Martin B, Walding A
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 21, 492 (2011).
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  • Discovery of novel and orally active FXR agonists for the potential treatment of dyslipidemia & diabetes Richter HGF, Benson GM, Blum D, Chaput E, Feng S, Gardes C, Grether U, Hartman P, Kuhn B, Martin RE, Plancher JM, Rudolph MG, Schuler F, Taylor S, Bleicher KH
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 21, 191 (2011).
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  • Crystal structure of the open conformation of the mammalian chaperonin CCT in complex with tubulin Munoz IG, Yebenes H, Zhou M, Mesa P, Serna M, Park AY, Bragado-Nilsson E, Beloso A, de Carcer G, Malumbres M, Robinson CV, Valpuesta JM, Montoya G
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 18, 14 (2011).
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  • Selective irreversible inhibition of a protease by targeting a noncatalytic cysteine Hagel M, Niu DQ, St Martin T, Sheets MP, Qiao LX, Bernard H, Karp RM, Zhu ZD, Labenski MT, Chaturvedi P, Nacht M, Westlin WF, Petter RC, Singh J
    NATURE CHEMICAL BIOLOGY 7, 22 (2011).
    DOI: 10.1038/NCHEMBIO.492

2010

  • Enhancement of the thermostability and the catalytic efficiency of Bacillus pumilus CBS protease by site-directed mutagenesis Jaouadi B, Aghajari N, Haser R, Bejar S
    BIOCHIMIE 92, 360 (2010).
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  • The acid tolerant L-arabinose isomerase from the food grade Lactobacillus sakei 23K is an attractive D-tagatose producer Rhimi M, Ilhammami R, Bajic G, Boudebbouze S, Maguin E, Haser R, Aghajari N
    BIORESOURCE TECHNOLOGY 101, 9171 (2010).
    DOI: 10.1016/j.biortech.2010.07.036
  • Efficient bioconversion of lactose in milk and whey: immobilization and biochemical characterization of a beta-galactosidase from the dairy Streptococcus thermophilus LMD9 strain Rhimi M, Boisson A, Dejob M, Boudebouze S, Maguin E, Haser R, Aghajari N
    RESEARCH IN MICROBIOLOGY 161, 515 (2010).
    DOI: 10.1016/j.resmic.2010.04.011
  • UV and X-ray structural studies of a 101-residue long Tat protein from a HIV-1 primary isolate and of its mutated, detoxified, vaccine candidate Foucault M, Mayol K, Receveur-Brechot V, Bussat MC, Klinguer-Hamour C, Verrier B, Beck A, Haser R, Gouet P, Guillon C
    PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 78, 1441 (2010).
    DOI: 10.1002/prot.22661
  • The Extended Conformation of the 2.9-angstrom Crystal Structure of the Three-PASTA Domain of a Ser/Thr Kinase from the Human Pathogen Staphylococcus aureus Paracuellos P, Ballandras A, Robert X, Kahn R, Herve M, Mengin-Lecreulx D, Cozzone AJ, Duclos B, Gouet P
    JOURNAL OF MOLECULAR BIOLOGY 404, 847 (2010).
    DOI: 10.1016/j.jmb.2010.10.012
  • 20S Proteasome Inhibition: Designing Noncovalent Linear Peptide Mimics of the Natural Product TMC-95A Groll M, Gallastegui N, Marechal X, Le Ravalec V, Basse N, Richy N, Genin E, Huber R, Moroder L, Vidal J, Reboud-Ravaux M
    CHEMMEDCHEM 5, 1701 (2010).
    DOI: 10.1002/cmdc.201000293
  • Structural Basis for Apoptosis Inhibition by Epstein-Barr Virus BHRF1 Kvansakul M, Wei AH, Fletcher JI, Willis SN, Chen L, Roberts AW, Huang DCS, Colman PM
    PLOS PATHOGENS 6, e1001236 (2010).
    DOI: 10.1371/journal.ppat.1001236
  • Unique molecular recognition of CD20 by the type II CD20 antibody GA101 Niederfellner GJ, Lammens A, Georges GJ, Schwaiger M, Franke A, Wiechmann K, Moessner E, Umana P, Hopfner KP, Klein C
    EJC SUPPLEMENTS 8, 75 (2010).
  • Towards structural studies of the old yellow enzyme homologue SYE4 from Shewanella oneidensis and its complexes at atomic resolution Elegheert J, van den Hemel D, Dix I, Stout J, Van Beeumen J, Brige A, Savvides SN
    ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS 66, 85 (2010).
    DOI: 10.1107/S1744309109050386
  • Crystallographic analysis reveals a unique lidocaine binding site on human serum albumin Hein KL, Kragh-Hansen U, Morth JP, Jeppesen MD, Otzen D, Moller JV, Nissen P
    JOURNAL OF STRUCTURAL BIOLOGY 171, 353 (2010).
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  • Structural identification of cation binding pockets in the plasma membrane proton pump Ekberg K, Pedersen BP, Sorensen DM, Nielsen AK, Veierskov B, Nissen P, Palmgren MG, Buch-Pedersen MJ
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 107, 21400 (2010).
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  • Staphylococcus aureus elongation factor G - structure and analysis of a target for fusidic acid Chen Y, Koripella RK, Sanyal S, Selmer M
    FEBS JOURNAL 277, 3789 (2010).
    DOI: 10.1111/j.1742-4658.2010.07780.x
  • Molecular basis of coiled-coil oligomerization-state specificity Ciani B, Bjelic S, Honnappa S, Jawhari H, Jaussi R, Payapilly A, Jowitt T, Steinmetz MO, Kammerer RA
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 107, 19850 (2010).
    DOI: 10.1073/pnas.1008502107
  • Solution Structure of Human Growth Arrest and DNA Damage 45 alpha (Gadd45 alpha) and Its Interactions with Proliferating Cell Nuclear Antigen (PCNA) and Aurora A Kinase Sanchez R, Pantoja-Uceda D, Prieto J, Diercks T, Marcaida MJ, Montoya G, Campos-Olivas R, Blanco FJ
    JOURNAL OF BIOLOGICAL CHEMISTRY 285, 22196 (2010).
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  • The architecture of respiratory complex I Efremov RG, Baradaran R, Sazanov LA
    NATURE 465, 441 (2010).
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  • Gremlin is a novel agonist of the major proangiogenic receptor VEGFR2 Mitola S, Ravelli C, Moroni E, Salvi V, Leali D, Ballmer-Hofer K, Zammataro L, Presta M
    BLOOD 116, 3677 (2010).
    DOI: 10.1182/blood-2010-06-291930
  • Crystal structure of bacterial RNA polymerase bound with a transcription inhibitor protein Tagami S, Sekine S, Kumarevel T, Hino N, Murayama Y, Kamegamori S, Yamamoto M, Sakamoto K, Yokoyama S
    NATURE 468, 978 (2010).
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  • A Tandem SH2 Domain in Transcription Elongation Factor Spt6 Binds the Phosphorylated RNA Polymerase II C-terminal Repeat Domain (CTD) Sun M, Lariviere L, Dengl S, Mayer A, Cramer P
    JOURNAL OF BIOLOGICAL CHEMISTRY 285, 41597 (2010).
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  • Radical mechanism of cyanophage phycoerythrobilin synthase (PebS). Busch AWU, Reijerse EJ, Lubitz W, Hofmann E, Frankenberg-Dinkel N
    BIOCHEMICAL JOURNAL 433, 469 (2010).
  • Design and optimization of new piperidines as renin inhibitors Corminboeuf O, Bezencon O, Grisostomi C, Remen L, Richard-Bildstein S, Bur D, Prade L, Hess P, Strickner P, Fischli W, Steiner B, Treiber A
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 20, 6286 (2010).
    DOI: 10.1016/j.bmcl.2010.08.086
  • A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions Buttar D, Colclough N, Gerhardt S, MacFaul PA, Phillips SD, Plowright A, Whittamore P, Tam K, Maskos K, Steinbacher S, Steuber H
    BIOORGANIC & MEDICINAL CHEMISTRY 18, 7486 (2010).
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  • The structural basis for catalysis and substrate specificity of a rhomboid protease Vinothkumar KR, Strisovsky K, Andreeva A, Christova Y, Verhelst S, Freeman M
    EMBO JOURNAL 29, 3797 (2010).
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  • Of Bits and Bugs - On the Use of Bioinformatics and a Bacterial Crystal Structure to Solve a Eukaryotic Repeat-Protein Structure Graebsch A, Roche S, Kostrewa D, Soding J, Niessing D
    PLOS ONE 5, e13402 (2010).
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  • Four KH domains of the C. elegans Bicaudal-C ortholog GLD-3 form a globular structural platform Nakel K, Hartung SA, Bonneau F, Eckmann CR, Conti E
    RNA-A PUBLICATION OF THE RNA SOCIETY 16, 2058 (2010).
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    STRUCTURE 18, 528 (2010).
    DOI: 10.1016/j.str.2010.01.015
  • DNA stretching in the nucleosome facilitates alkylation by an intercalating antitumour agent Davey GE, Wu B, Dong YC, Surana U, Davey CA
    NUCLEIC ACIDS RESEARCH 38, 2081 (2010).
    DOI: 10.1093/nar/gkp1174
  • Macromolecular crystal data phased by negative-stained electron-microscopy reconstructions Trapani S, Schoehn G, Navaza J, Abergel C
    ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 66, 514 (2010).
  • The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5 Schiemann K, Finsinger D, Zenke F, Amendt C, Knochel T, Bruge D, Buchstaller HP, Emde U, Stahle W, Anzali S
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 20, 1491 (2010).
    DOI: 10.1016/j.bmcl.2010.01.110
  • X-ray structures of the peridinin-chlorophyll-protein reconstituted with different chlorophylls Schulte T, Hiller RG, Hofmann E
    FEBS LETTERS 584, 973 (2010).
    DOI: 10.1016/j.febslet.2010.01.041
  • Structural determinants of growth factor binding and specificity by VEGF receptor 2 Leppanen VM, Prota AE, Jeltsch M, Anisimov A, Kalkkinen N, Strandin T, Lankinen H, Goldman A, Ballmer-Hofer K, Alitalo K
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 107, 2425 (2010).
    DOI: 10.1073/pnas.0914318107
  • Structure of Adenovirus Type 21 Knob in Complex with CD46 Reveals Key Differences in Receptor Contacts among Species B Adenoviruses Cupelli K, Muller S, Persson BD, Jost M, Arnberg N, Stehle T
    JOURNAL OF VIROLOGY 84, 3189 (2010).
    DOI: 10.1128/JVI.01964-09
  • Crystal structure of the carnitine transporter and insights into the antiport mechanism Tang L, Bai L, Wang W-H, Jiang T
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 17, 492 (2010).
  • Crystal Structure of HIV-1 Reverse Transcriptase Bound to a Non-Nucleoside Inhibitor with a Novel Mechanism of Action Freisz S, Bec G, Radi M, Wolff P, Crespan E, Angeli L, Dumas P, Maga G, Botta M, Ennifar E
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 49, 1805 (2010).
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  • Structure of the HCMV UL16-MICB Complex Elucidates Select Binding of a Viral Immunoevasin to Diverse NKG2D Ligands Muller S, Zocher G, Steinle A, Stehle T
    PLOS PATHOGENS 6, e1000723 (2010).
    DOI: 10.1371/journal.ppat.1000723
  • Cupredoxin-like domains in haemocyanins Jaenicke E, Buchler K, Markl J, Decker H, Barends TRM
    BIOCHEMICAL JOURNAL 426, 373 (2010).
    DOI: 10.1042/BJ20091501
  • GGA Autoinhibition Revisited Cramer JF, Gustafsen C, Behrens MA, Oliveira CLP, Pedersen JS, Madsen P, Petersen CM, Thirup SS
    TRAFFIC 11, 259 (2010).
    DOI: 10.1111/j.1600-0854.2009.01017.x
  • Structure at 1.0 resolution of a high-potential iron-sulfur protein involved in the aerobic respiratory chain of Rhodothermus marinus Stelter M, Melo AMP, Hreggvidsson GO, Hjorleifsdottir S, Saraiva LM, Teixeira M, Archer M
    JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 15, 303 (2010).
    DOI: 10.1007/s00775-009-0603-8
  • Modulation of protein properties in living cells using nanobodies Kirchhofer A, Helma J, Schmidthals K, Frauer C, Cui S, Karcher A, Pellis M, Muyldermans S, Casas-Delucchi CS, Cardoso MC, Leonhardt H, Hopfner KP, Rothbauer U
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 17, 133 (2010).
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  • Absence of a catalytic water confers resistance to the neurotoxin gabaculine Orriss GL, Patel TR, Sorensen J, Stetefeld J
    FASEB JOURNAL 24, 404 (2010).
    DOI: 10.1096/fj.09-138297
  • Characterization of a Carbon-Carbon Hydrolase from Mycobacterium tuberculosis Involved in Cholesterol Metabolism Lack NA, Yam KC, Lowe ED, Horsman GP, Owen RL, Sim E, Eltis LD
    JOURNAL OF BIOLOGICAL CHEMISTRY 285, 434 (2010).
    DOI: 10.1074/jbc.M109.058081
  • Nuclear Import Mechanism of the EJC Component Mago-Y14 Revealed by Structural Studies of Importin 13 Bono F, Cook AG, Grunwald M, Ebert J, Conti E
    MOLECULAR CELL 37, 211 (2010).
    DOI: 10.1016/j.molcel.2010.01.007
  • Crystal Structure of a Cisplatin-1,3-GTG Cross-Link Inside DNA Polymerase Reissner T, Schneider S, Schorr S, Carell T
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 49, 3077 (2010).
  • Crystal Structure of an Aquabirnavirus Particle: Insights into Antigenic Diversity and Virulence Determinism Coulibaly F, Chevalier C, Delmas B, Rey FA
    JOURNAL OF VIROLOGY 84, 1792 (2010).
    DOI: 10.1128/JVI.01536-09
  • Crystallization and preliminary X-ray crystallographic analysis of Thermus thermophilus transcription elongation complex bound to Gfh1 Tagami S, Sekine S, Kumarevel T, Yamamoto M, Yokoyama S
    ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS 66, 64 (2010).
    DOI: 10.1107/S1744309109049215

2009

  • Pore Mutations in Ammonium Transporter AMT1 with Increased Electrogenic Ammonium Transport Activity Loque D, Mora SI, Andrade SLA, Pantoja O, Frommer WB
    JOURNAL OF BIOLOGICAL CHEMISTRY 284, 24988 (2009).
    DOI: 10.1074/jbc.M109.020842
  • Cytosolic Viral Sensor RIG-I Is a 5 '-Triphosphate-Dependent Translocase on Double-Stranded RNA Myong S, Cui S, Cornish PV, Kirchhofer A, Gack MU, Jung JU, Hopfner KP, Ha T
    SCIENCE 323, 1070 (2009).
    DOI: 10.1126/science.1168352
  • Crystal Structure Analysis Reveals That the Novel Type II Anti-CD20 Antibody GA101 Interacts with a Similar Epitope as Rituximab and Ocrelizumab but in a Fundamentally Different Way Niederfellner GJ, Lammens A, Schwaiger M, Georges G, Wiechmann K, Franke A, Schaefer W, Jenewein S, Slootstra J, Moessner E, Umana P, Hopfner KP, Klein C
    BLOOD 114, 1435 (2009).
  • Lessons from structural and biochemical studies on the archaeal exosome Hartung S, Hopfner KP
    BIOCHEMICAL SOCIETY TRANSACTIONS 37, 83 (2009).
    DOI: 10.1042/BST0370083
  • The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA Pippig DA, Hellmuth JC, Cui S, Kirchhofer A, Lammens K, Lammens A, Schmidt A, Rothenfusser S, Hopfner KP
    NUCLEIC ACIDS RESEARCH 37, 2014 (2009).
    DOI: 10.1093/nar/gkp059
  • Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation Quick M, Winther AML, Shi L, Nissen P, Weinstein H, Javitch JA
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106, 5563 (2009).
    DOI: 10.1073/pnas.0811322106
  • Plant Photosystem I Design in the Light of Evolution Amunts A, Nelson N
    STRUCTURE 17, 637 (2009).
    DOI: 10.1016/j.str.2009.03.006
  • Plant Photosystem I - The Most Efficient Nano-Photochemical Machine Nelson N
    JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 9, 1709 (2009).
    DOI: 10.1166/jnn.2009.SI01
  • Novel sample preparation technique for protein crystal X-ray crystallographic analysis combining microfluidics and acoustic manipulation Oberti S, Moller D, Gutmann S, Neild A, Dual J
    JOURNAL OF APPLIED CRYSTALLOGRAPHY 42, 636 (2009).
    DOI: 10.1107/S0021889809019177
  • New classes of potent and bioavailable human renin inhibitors Remen L, Bezencon O, Richard-Bildstein S, Prade DBL, Corminboeuf O, Boss C, Grisostomi C, Sifferlen T, Strickner P, Hess P, Delahaye S, Treiber A, Weller T, Binkert C, Steiner B, Fischli W
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 19, 6762 (2009).
    DOI: 10.1016/j.bmcl.2009.09.104
  • Structural basis of chemokine sequestration by a tick chemokine binding protein: the crystal structure of the complex between Evasin-1 and CCL3 Dias JM, Losberger C, Deruaz M, Power CA, Proudfoot AEI, Shaw JP
    PLOS ONE 4, 8514 (2009).
  • Activation of Anthranilate Phosphoribosyltransferase from Sulfolobus solfataricus by Removal of Magnesium Inhibition and Acceleration of Product Release Schlee S, Deuss M, Bruning M, Ivens A, Schwab T, Hellmann N, Mayans O, Sterner R
    BIOCHEMISTRY 48, 5199 (2009).
    DOI: 10.1021/bi802335s
  • Crystal Structure of a Nucleocapsid-Like Nucleoprotein-RNA Complex of Respiratory Syncytial Virus Tawar RG, Duquerroy S, Vonrhein C, Varela PF, Damier-Piolle L, Castagne N, MacLellan K, Bedouelle H, Bricogne G, Bhella D, Eleouet JF, Rey FA
    SCIENCE 326, 1279 (2009).
    DOI: 10.1126/science.1177634
  • The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational State Gao YG, Selmer M, Dunham CM, Weixlbaumer A, Kelley AC, Ramakrishnan V
    SCIENCE 326, 694 (2009).
    DOI: 10.1126/science.1179709
  • Bothnia dystrophy is caused by domino-like rearrangements in cellular retinaldehyde-binding protein mutant R234W He X, Lobsiger J, Stocker A
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106, 18545 (2009).
  • Lipidic Sponge Phase Crystal Structure of a Photosynthetic Reaction Center Reveals Lipids on the Protein Surface Wohri AB, Wahlgren WY, Malmerberg E, Johansson LC, Neutze R, Katona G
    BIOCHEMISTRY 48, 9831 (2009).
    DOI: 10.1021/bi90054
  • Design of selective Cathepsin inhibitors Bethel PA, Gerhardt S, Jones EV, Kenny PW, Karoutchi GI, Morley AD, Oldham K, Rankine N, Augustin M, Krapp S, Simader H, Steinbacher S
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 19, 4622 (2009).
    DOI: 10.1016/j.bmcl.2009.06.090
  • Improving potency and selectivity of a new class of non-Zn-chelating MMP-13 inhibitors Heim-Riether A, Taylor SJ, Liang S, Gao DA, Xiong ZM, August EM, Collins BK, Farmer BT, Haverty K, Hill-Drzewi M, Junker HD, Margarit SM, Moss N, Neumann T, Proudfoot JR, Keenan LS, Sekul R, Zhang Q, Li J, Farrow NA
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 19, 5321 (2009).
    DOI: 10.1016/j.bmcl.2009.07.151
  • Structural and Functional Studies of the Yeast Class II Hda1 Histone Deacetylase Complex Lee JH, Maskos K, Huber R
    JOURNAL OF MOLECULAR BIOLOGY 391, 744 (2009).
    DOI: 10.1016/j.jmb.2009.06.059
  • Crystal Structure of Dinitrogenase Reductase-activating Glycohydrolase (DRAG) Reveals Conservation in the ADP-Ribosylhydrolase Fold and Specific Features in the ADP-Ribose-binding Pocket Li XD, Huergo LF, Gasperina A, Pedrosa FO, Merrick M, Winkler FK
    JOURNAL OF MOLECULAR BIOLOGY 390, 737 (2009).
    DOI: 10.1016/j.jmb.2009.05.031
  • Design and Preparation of Potent, Nonpeptidic, Bioavailable Renin Inhibitors Bezencon O, Bur D, Weller T, Richard-Bildstein S, Remen L, Sifferlen T, Corminboeuf O, Grisostomi C, Boss C, Prade L, Delahaye S, Treiber A, Strickner P, Binkert C, Hess P, Steiner B, Fischli W
    JOURNAL OF MEDICINAL CHEMISTRY 52, 3689 (2009).
    DOI: 10.1021/jm900022f
  • McsB Is a Protein Arginine Kinase That Phosphorylates and Inhibits the Heat-Shock Regulator CtsR Fuhrmann J, Schmidt A, Spiess S, Lehner A, Turgay K, Mechtler K, Charpentier E, Clausen T
    SCIENCE 324, 1323 (2009).
    DOI: 10.1126/science.1170088
  • The Three-dimensional Structure of a Mycobacterial DapD Provides Insights into DapD Diversity and Reveals Unexpected Particulars about the Enzymatic Mechanism Schuldt L, Weyand S, Kefala G, Weiss MS
    JOURNAL OF MOLECULAR BIOLOGY 389, 863 (2009).
    DOI: 10.1016/j.jmb.2009.04.046
  • Structural basis for the erythro-stereospecificity of the L-arginine oxygenase VioC in viomycin biosynthesis Helmetag V, Samel SA, Thomas MG, Marahiel MA, Essen LO
    FEBS JOURNAL 276, 3669 (2009).
    DOI: 10.1111/j.1742-4658.2009.07085.x
  • Dipeptidyl nitrile inhibitors of Cathepsin L Asaad N, Bethel PA, Coulson MD, Dawson JE, Ford SJ, Gerhardt S, Grist M, Hamlin GA, James MJ, Jones EV, Karoutchi GI, Kenny PW, Morley AD, Oldham K, Rankine N, Ryan D, Wells SL, Wood L, Augustin M, Krapp S, Simader H, Steinbacher S
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 19, 4280 (2009).
    DOI: 10.1016/j.bmcl.2009.05.071
  • Discovery of 4-azaindoles as novel inhibitors of c-Met kinase Porter J, Lumb S, Franklin RJ, Gascon-Simorte JM, Calmiano M, Le Riche K, Lallemand B, Keyaerts J, Edwards H, Maloney A, Delgado J, King L, Foley A, Lecomte F, Reuberson J, Meier C, Batchelor M
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 19, 2780 (2009).
    DOI: 10.1016/j.bmcl.2009.03.110
  • Identification of an N-oxide pyridine GW4064 analog as a potent FXR agonist Feng S, Yang M, Zhang Z, Wang Z, Hong D, Richter H, Benson GM, Bleicher K, Grether U, Martin RE, Plancher J-M, Kuhn B, Rudolph MG, Chen L
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 19, 2595 (2009).
  • Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome Voorhees RM, Weixlbaumer A, Loakes D, Kelley AC, Ramakrishnan V
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 16, 528 (2009).
    DOI: 10.1038/nsmb.1577
  • Design and Biological Evaluation of Novel, Balanced Dual PPAR alpha/gamma Agonists Grether U, Benardeau A, Benz J, Binggeli A, Blum D, Hilpert H, Kuhn B, Marki HP, Meyer M, Mohr P, Puntener K, Raab S, Ruf A, Schlatter D
    CHEMMEDCHEM 4, 951 (2009).
    DOI: 10.1002/cmdc.200800425
  • Design of novel aminopyrrolidine factor Xa inhibitors from a screening hit Zbinden KG, Anselm L, Banner DW, Benz J, Blasco F, Decoret G, Himber J, Kuhn B, Panday N, Ricklin F, Risch P, Schlatter D, Stahl M, Thomi S, Unger R, Haap W
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 44, 2787 (2009).
    DOI: 10.1016/j.ejmech.2008.12.025
  • BI 6727, A Polo-like Kinase Inhibitor with Improved Pharmacokinetic Profile and Broad Antitumor Activity Rudolph D, Steegmaier M, Hoffmann M, Grauert M, Baum A, Quant J, Haslinger C, Garin-Chesa P, Adolf GR
    CLINICAL CANCER RESEARCH 15, 3094 (2009).
    DOI: 10.1158/1078-0432.CCR-08-2445
  • Cyclopiazonic Acid Is Complexed to a Divalent Metal Ion When Bound to the Sarcoplasmic Reticulum Ca2+-ATPase Laursen M, Bublitz M, Moncoq K, Olesen C, Moller JV, Young HS, Nissen P, Morth JP
    JOURNAL OF BIOLOGICAL CHEMISTRY 284, 13513 (2009).
    DOI: 10.1074/jbc.C900031200
  • Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5-type I receptor specificity Kotzsch A, Nickel J, Seher A, Sebald W, Muller TD
    EMBO JOURNAL 28, 937 (2009).
    DOI: 10.1038/emboj.2009.37
  • Structural Base for Enzymatic Cyclodextrin Hydrolysis Buedenbender S, Schulz GE
    JOURNAL OF MOLECULAR BIOLOGY 385, 606 (2009).
    DOI: 10.1016/j.jmb.2008.10.085
  • Structure and Action of the Myxobacterial Chondrochloren Halogenase CndH: A New Variant of FAD-dependent Halogenases Buedenbender S, Rachid S, Muller R, Schulz GE
    JOURNAL OF MOLECULAR BIOLOGY 385, 520 (2009).
    DOI: 10.1016/j.jmb.2008.10.057
  • Macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors with activity in vivo Machauer R, Laumen K, Veenstra S, Rondeau JM, Tintelnot-Blomley M, Betschart C, Jaton AL, Desrayaud S, Staufenbiel M, Rabe S, Paganetti P, Neumann U
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 19, 1366 (2009).
    DOI: 10.1016/j.bmcl.2009.01.055
  • Ligands bind to Sortilin in the tunnel of a ten-bladed beta-propeller domain Quistgaard EM, Madsen P, Groftehauge MK, Nissen P, Petersen CM, Thirup SS
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 16, 96 (2009).
    DOI: 10.1038/nsmb.1543
  • Discovery of a novel series of quinoxalines as inhibitors of c-Met kinase Porter J, Lumb S, Lecomte F, Reuberson J, Foley A, Calmiano M, le Riche K, Edwards H, Delgado J, Franklin RJ, Gascon-Simorte JM, Maloney A, Meier C, Batchelor M
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 19, 397 (2009).
    DOI: 10.1016/j.bmcl.2008.11.062
  • Dimerization and Protein Binding Specificity of the U2AF Homology Motif of the Splicing Factor Puf60 Corsini L, Hothorn M, Stier G, Rybin V, Scheffzek K, Gibson TJ, Sattler M
    JOURNAL OF BIOLOGICAL CHEMISTRY 284, 630 (2009).
    DOI: 10.1074/jbc.M805395200
  • Large, larger, largest - a family of cluster-based tantalum copper aluminides with giant unit cells. II. The cluster structure Conrad M, Harbrecht B, Weber T, Jung DY, Steurer W
    ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE 65, 318 (2009).
    DOI: 10.1107/S0108768109014013
  • Large, larger, largest - a family of cluster-based tantalum copper aluminides with giant unit cells. I. Structure solution and refinement Weber T, Dshemuchadse J, Kobas M, Conrad M, Harbrecht B, Steurer W
    ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE 65, 308 (2009).
  • The Picobirnavirus Crystal Structure Provides Functional Insights Into Virion Assembly and Cell Entry Duquerroy S, Da Costa B, Henry C, Vigouroux A, Libersou S, Lepault J, Navaza J, Delmas B, Rey FA
    EMBO JOURNAL 28, 1655 (2009).
  • Metzincin's canonical methionine is responsible for the structural integrity of the zinc-binding site Oberholzer AE, Bumann M, Hege T, Russo S, Baumann U
    BIOLOGICAL CHEMISTRY 390, 875 (2009).
    DOI: 10.1515/BC.2009.100
  • Crystal Structure of Enzyme I of the Phosphoenolpyruvate Sugar Phosphotransferase System in the Dephosphorylated State Oberholzer AE, Schneider P, Siebold C, Baumann U, Erni B
    JOURNAL OF BIOLOGICAL CHEMISTRY 284, 33169 (2009).
    DOI: 10.1074/jbc.M109.057612
  • Simulation of X-ray frames from macromolecular crystals using a ray-tracing approach Diederichs K
    ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 65, 535 (2009).
    DOI: 10.1107/S0907444909010282
  • Trinity revealed: Stoichiometric complex assembly of a bacterial multidrug efflux pump Pos KM
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106, 6893 (2009).
    DOI: 10.1073/pnas.0902837106
  • Drug transport mechanism of the AcrB efflux pump Pos KM
    BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS 1794, 782 (2009).
    DOI: 10.1016/j.bbapap.2008.12.015
  • Trinity revealed: Stoichiometric complex assembly of a bacterial multidrug efflux pump (vol 106, pg 6893, 2009) Pos KM
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106, 9534 (2009).
    DOI: 10.1073/pnas.0904722106
  • The mechanism of vault opening from the high resolution structure of the N-terminal repeats of MVP Querol-Audi J, Casanas A, Uson I, Luque D, Caston JR, Fita I, Verdaguer N
    EMBO JOURNAL 28(21), 3450 (2009).
  • Crucial Role of Asp408 in the Proton Translocation Pathway of Multidrug Transporter AcrB: Evidence from Site-Directed Mutagenesis and Carbodiimide Labeling Seeger MA, von Ballmoos C, Verrey F, Pos KM
    BIOCHEMISTRY 48, 5801 (2009).
    DOI: 10.1021/bi900446j
  • Structural and functional aspects of the multidrug efflux pump AcrB Eicher T, Brandstatter L, Pos KM
    BIOLOGICAL CHEMISTRY 390, 693 (2009).
    DOI: 10.1515/BC.2009.090
  • The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE Neubauer C, Gao YG, Andersen KR, Dunham CM, Kelley AC, Hentschel J, Gerdes K, Ramakrishnan V, Brodersen DE
    CELL 139(6), 1084 (2009).
  • Cyanobacteria contain a structural homologue of the Hfq protein with altered RNA-binding properties Boeggild A, Overgaard M, Valentin-Hansen P, Brodersen DE
    FEBS JOURNAL 276(14), 3904 (2009).
  • Insights into the DNA cleavage mechanism of human LINE-1 retrotransposon endonuclease Repanas K, Fuentes G, Cohen SX, Bonvin AMJJ, Perrakis A
    PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 74, 917 (2009).
    DOI: 10.1002/prot.22201
  • Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing De Marco V, Gillespie PJ, Li A, Karantzelis N, Christodoulou E, Klompmaker R, van Gerwen S, Fish A, Petoukhov MV, Iliou MS, Lygerou Z, Medema RH, Blow JJ, Svergun DI, Taraviras S, Perrakis A
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106, 19807 (2009).
    DOI: 10.1073/pnas.0905281106
  • Molecular basis for insulin fibril assembly Ivanova MI, Sievers SA, Sawaya MR, Wall JS, Eisenberg D
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106(45), 18990 (2009).
  • Mammalian end binding proteins control persistent microtubule growth Komarova Y, De Groot CO, Grigoriev I, Gouveia SM, Munteanu EL, Schober JM, Honnappa S, Buey RM, Hoogenraad CC, Dogterom M, Borisy GG, Steinmetz MO, Akhmanova A
    JOURNAL OF CELL BIOLOGY 184, 691 (2009).
    DOI: 10.1083/jcb.200807179
  • An EB1-Binding Motif Acts as a Microtubule Tip Localization Signal Honnappa S, Gouveia SM, Weisbrich A, Damberger FF, Bhavesh NS, Jawhari H, Grigoriev I, van Rijssel FJA, Buey RM, Lawera A, Jelesarov I, Winkler FK, Wuthrich K, Akhmanova A, Steinmetz MO
    CELL 138, 366 (2009).
    DOI: 10.1016/j.cell.2009.04.065
  • The Structure of Rat Liver Vault at 3.5 Angstrom Resolution Tanaka H, Kato K, Yamashita E, Sumizawa T, Zhou Y, Yao M, Iwasaki K, Yoshimura M, Tsukihara T
    SCIENCE 323, 384 (2009).
    DOI: 10.1126/science.1164975
  • The mRNA export protein DBP5 binds RNA and the cytoplasmic nucleoporin NUP214 in a mutually exclusive manner von Moeller H, Basquin C, Conti E
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 16, 247 (2009).
    DOI: 10.1038/nsmb.1561
  • Structures of the tRNA export factor in the nuclear and cytosolic states Cook AG, Fukuhara N, Jinek M, Conti E
    NATURE 461, 60 (2009).
    DOI: 10.1038/nature08394
  • A description of the structural determination procedures of a gap junction channel at 3.5A resolution Suga M, Maeda S, Nakagawa S, Yamashita E, Tsukihara T
    ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 65, 758 (2009).
  • Structural Basis and Enzymatic Mechanism of the Biosynthesis of C9- from C10-Monoterpenoid Indole Alkaloids Yang L, Hill M, Wang M, Panjikar S, Stoeckigt J
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 48, 5211 (2009).
  • How ATPases Unravel a Mystery Gallastegui N, Groll M
    STRUCTURE 17, 1279 (2009).
    DOI: 10.1016/j.str.2009.09.003
  • Interpreting a Low Resolution Map of Human U1 snRNP Using Anomalous Scatterers Oubridge C, Krummel DAP, Leung AKW, Li J, Nagai K
    STRUCTURE 17, 930 (2009).
    DOI: 10.1016/j.str.2009.05.009
  • Crystal structure of human spliceosomal U1 snRNP at 5.5 angstrom resolution Krummel DAP, Oubridge C, Leung AKW, Li J, Nagai K
    NATURE 458, 475 (2009).
    DOI: 10.1038/nature07851
  • Molecular and Mechanistic Properties of the Membrane-Bound Mitochondrial Monoamine Oxidases Edmondson DE, Binda C, Wang J, Upadhyay AK, Mattevi A
    BIOCHEMISTRY 48, 4220 (2009).
    DOI: 10.1021/bi900413g
  • Multiple pathways guide oxygen diffusion into flavoenzyme active sites Baron R, Riley C, Chenprakhon P, Thotsaporn K, Winter RT, Alfieri A, Forneris F, van Berkel WJH, Chaiyen P, Fraaije MW, Mattevi A, McCammon JA
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106, 10603 (2009).
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  • Structure of the connexin 26 gap junction channel at 3.5 angstrom resolution Maeda S, Nakagawa S, Suga M, Yamashita E, Oshima A, Fujiyoshi Y, Tsukihara T
    NATURE 458, 597 (2009).
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  • Crystal structure of Ultralente-A microcrystalline insulin suspension Wagner A, Diez J, Schulze-Briese C, Schluckebier G
    PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 74, 1018 (2009).
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  • Comments on Determination of X-ray flux using silicon pin diodes by R. L. Owen et al. (2009). J. Synchrotron Rad. 16, 143-151 Response Owen RL, Holton JM, Schulze-Briese C, Garman EF
    JOURNAL OF SYNCHROTRON RADIATION 16, 691 (2009).
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  • Determination of X-ray flux using silicon pin diodes Owen RL, Holton JM, Schulze-Briese C, Garman EF
    JOURNAL OF SYNCHROTRON RADIATION 16, 143 (2009).
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  • 3D Imaging of the Fermi Surface by Thermal Diffuse Scattering Bosak A, Hoesch M, Krisch M, Chernyshov D, Pattison P, Schulze-Briese C, Winkler B, Milman V, Refson K, Antonangeli D, Farber D
    PHYSICAL REVIEW LETTERS 103, 076403 (2009).
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  • The atomic structure of baculovirus polyhedra reveals the independent emergence of infectious crystals in DNA and RNA viruses Coulibaly F, Chiu E, Gutmann S, Rajendran C, Haebel PW, Ikeda K, Mori H, Ward VK, Schulze-Briese C, Metcalf P
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106, 22205 (2009).
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  • Structure-function studies of the RNA polymerase II elongation complex Brueckner F, Armache KJ, Cheung A, Damsma GE, Kettenberger H, Lehmann E, Sydow J, Cramer P
    ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 65, 112 (2009).
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  • RNA polymerase fidelity and transcriptional proofreading Sydow JF, Cramer P
    CURRENT OPINION IN STRUCTURAL BIOLOGY 19, 732 (2009).
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  • Proteins: how RNA polymerases work Editorial overview Cramer P, Arnold E
    CURRENT OPINION IN STRUCTURAL BIOLOGY 19, 680 (2009).
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  • The Crystal Structure of Human Pyrin B30.2 Domain: Implications for Mutations Associated with Familial Mediterranean Fever Weinert C, Grutter C, Roschitzki-Voser H, Mittl PRE, Grutter MG
    JOURNAL OF MOLECULAR BIOLOGY 394, 226 (2009).
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  • Crystal Structure of the Multidrug Exporter MexB from Pseudomonas aeruginosa Sennhauser G, Bukowska MA, Briand C, Grutter MG
    JOURNAL OF MOLECULAR BIOLOGY 389, 134 (2009).
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  • A Common Structural Basis for pH- and Calmodulin-mediated Regulation in Plant Glutamate Decarboxylase Gut H, Dominici P, Pilati S, Astegno A, Petoukhov MV, Svergun DI, Grutter MG, Capitani G
    JOURNAL OF MOLECULAR BIOLOGY 392, 334 (2009).
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  • Synthetic and structural studies on syringolin A and B reveal critical determinants of selectivity and potency of proteasome inhibition Clerc J, Groll M, Illich DJ, Bachmann AS, Huber R, Schellenberg B, Dudler R, Kaiser M
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106, 6507 (2009).
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  • Structure of Active IspH Enzyme from Escherichia coli Provides Mechanistic Insights into Substrate Reduction Grawert T, Rohdich F, Span I, Bacher A, Eisenreich W, Eppinger J, Groll M
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 48, 5756 (2009).
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  • Snapshots of the Fluorosalinosporamide/20S Complex Offer Mechanistic Insights for Fine Tuning Proteasome Inhibition Groll M, McArthur KA, Macherla VR, Manam RR, Potts BC
    JOURNAL OF MEDICINAL CHEMISTRY 52, 5420 (2009).
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  • A movie of the RNA polymerase nucleotide addition cycle Brueckner F, Ortiz J, Cramer P
    CURRENT OPINION IN STRUCTURAL BIOLOGY 19, 294 (2009).
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  • Torpedo Nuclease Rat1 Is Insufficient to Terminate RNA Polymerase II in Vitro Dengl S, Cramer P
    JOURNAL OF BIOLOGICAL CHEMISTRY 284, 21270 (2009).
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  • Structure and in Vivo Requirement of the Yeast Spt6 SH2 Domain Dengl S, Mayer A, Sun M, Cramer P
    JOURNAL OF MOLECULAR BIOLOGY 389, 211 (2009).
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  • Structural Basis of Transcription: Mismatch-Specific Fidelity Mechanisms and Paused RNA Polymerase II with Frayed RNA Sydow JF, Brueckner F, Cheung ACM, Damsma GE, Dengl S, Lehmann E, Vassylyev D, Cramer P
    MOLECULAR CELL 34, 710 (2009).
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  • Molecular Basis of Transcriptional Mutagenesis at 8-Oxoguanine Damsma GE, Cramer P
    JOURNAL OF BIOLOGICAL CHEMISTRY 284, 31658 (2009).
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  • RNA polymerase II-TFIIB structure and mechanism of transcription initiation Kostrewa D, Zeller ME, Armache KJ, Seizl M, Leike K, Thomm M, Cramer P
    NATURE 462, 323 (2009).
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  • Structure and mechanism of ATP-binding cassette transporters Locher KP
    PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES 364, 239 (2009).
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  • Distinct gate conformations of the ABC transporter BtuCD revealed by electron spin resonance spectroscopy and chemical cross-linking Goetz BA, Perozo E, Locher KP
    FEBS LETTERS 583, 266 (2009).
    DOI: 10.1016/j.febslet.2008.12.020
  • Distorted octahedral coordination of tungstate in a subfamily of specific binding proteins Hollenstein K, Comellas-Bigler M, Bevers LE, Feiters MC, Meyer-Klaucke W, Hagedoorn PL, Locher KP
    JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 14, 663 (2009).
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  • Crystal Structure of the T(6-4)C Lesion in Complex with a (6-4) DNA Photolyase and Repair of UV-Induced (6-4) and Dewar Photolesions Glas AF, Schneider S, Maul MJ, Hennecke U, Carell T
    CHEMISTRY-A EUROPEAN JOURNAL 15, 10387 (2009).
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  • A fast selenium derivatization strategy for crystallization and phasing of RNA structures Olieric V, Rieder U, Lang K, Serganov A, Schulze-Briese C, Micura R, Dumas P, Ennifar E
    RNA-A PUBLICATION OF THE RNA SOCIETY 15, 707 (2009).
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  • Imperfect pseudo-merohedral twinning in crystals of fungal fatty acid synthase Jenni S, Ban N
    ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 65, 101 (2009).
    DOI: 10.1107/S0907444909000778
  • An Arginine Switch in the Species B Adenovirus Knob Determines High-Affinity Engagement of Cellular Receptor CD46 Persson BD, Muller S, Reiter DM, Schmitt BBT, Marttila M, Sumowski CV, Schweizer S, Scheu U, Ochsenfeld C, Arnberg N, Stehle T
    JOURNAL OF VIROLOGY 83, 673 (2009).
    DOI: 10.1128/JVI.01967-08
  • The structure of dimethylallyl tryptophan synthase reveals a common architecture of aromatic prenyltransferases in fungi and bacteria Metzger U, Schall C, Zocher G, Unsold I, Stec E, Li SM, Heide L, Stehle T
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106, 14309 (2009).
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  • A novel dimerization motif in the C-terminal domain of the Thermus thermophilus DEAD box helicase Hera confers substantial flexibility Klostermeier D, Rudolph MG
    NUCLEIC ACIDS RESEARCH 37, 421 (2009).
    DOI: 10.1093/nar/gkn947
  • Use of Acetylcholine Binding Protein in the Search for Novel alpha 7 Nicotinic Receptor Ligands. In Silico Docking, Pharmacological Screening, and X-ray Analysis Ulens C, Akdemir A, Jongejan A, van Elk R, Bertrand S, Perrakis A, Leurs R, Smit AB, Sixma TK, Bertrand D, de Esch IJP
    JOURNAL OF MEDICINAL CHEMISTRY 52, 2372 (2009).
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  • Class I Major Histocompatibility Complexes Loaded by a Periodate Trigger Rodenko B, Toebes M, Celie PHN, Perrakis A, Schumacher TNM, Ovaa H
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 131, 12305 (2009).
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  • UV-Induced Ligand Exchange in MHC Class I Protein Crystals Celie PHN, Toebes M, Rodenko B, Ovaa H, Perrakis A, Schumacher TNM
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 131, 12298 (2009).
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  • Oxidoreductase activity of oligosaccharyltransferase subunits Ost3p and Ost6p defines site-specific glycosylation efficiency Schulz BL, Stirnimann CU, Grimshaw JPA, Brozzo MS, Fritsch F, Mohorko E, Capitani G, Glockshuber R, Grutter MG, Aebi M
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106, 11061 (2009).
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  • Crystallization and preliminary characterization of the Thermus thermophilus RNA helicase Hera C-terminal domain Rudolph MG, Wittmann JG, Klostermeier D
    ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS 65, 248 (2009).
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  • The structure of a cytolytic alpha-helical toxin pore reveals its assembly mechanism Mueller M, Grauschopf U, Maier T, Glockshuber R, Ban N
    NATURE 459, 726 (2009).
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  • High-Affinity IgE Recognition of a Conformational Epitope of the Major Respiratory Allergen Phl p 2 As Revealed by X-Ray Crystallography Padavattan S, Flicker S, Schirmer T, Madritsch C, Randow S, Reese G, Vieths S, Lupinek C, Ebner C, Valenta R, Markovic-Housley Z
    JOURNAL OF IMMUNOLOGY 182, 2141 (2009).
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  • Crystal Structures of YkuI and Its Complex with Second Messenger Cyclic Di-GMP Suggest Catalytic Mechanism of Phosphodiester Bond Cleavage by EAL Domains Minasov G, Padavattan S, Shuvalova L, Brunzelle JS, Miller DJ, Basle A, Massa C, Collart FR, Schirmer T, Anderson WF
    JOURNAL OF BIOLOGICAL CHEMISTRY 284, 13174 (2009).
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  • X-ray Structure of the C-Terminal Domain of a Prokaryotic Cation-Chloride Cotransporter Warmuth S, Zimmermann I, Dutzler R
    STRUCTURE 17, 538 (2009).
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  • Crystal Structure of the Caseinolytic Protease Gene Regulator, a Transcriptional Activator in Actinomycetes Russo S, Schweitzer JE, Polen T, Bott M, Pohl E
    JOURNAL OF BIOLOGICAL CHEMISTRY 284, 5208 (2009).
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  • Heme uptake across the outer membrane as revealed by crystal structures of the receptor-hemophore complex Krieg S, Huche F, Diederichs K, Izadi-Pruneyre N, Lecroisey A, Wandersman C, Delepelaire P, Welte W
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106, 1045 (2009).
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  • A structural view of translation initiation in bacteria Simonetti A, Marzi S, Jenner L, Myasnikov A, Romby P, Yusupova G, Klaholz BP, Yusupov M
    CELLULAR AND MOLECULAR LIFE SCIENCES 66, 423 (2009).
  • Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel Hilf RJC, Dutzler R
    NATURE 457, 115 (2009).
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  • Identification, structure, and functional requirement of the Mediator submodule Med7N/31 Koschubs T, Seizl M, Lariviere L, Kurth F, Baumli S, Martin DE, Cramer P
    EMBO JOURNAL 28, 69 (2009).
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  • X-Ray structure of a pentameric ligand-gated ion channel in an apparently open conformation Bocquet N, Nury H, Baaden M, Le Poupon C, Changeux JP, Delarue M, Corringer PJ
    NATURE 457, 111 (2009).

2008

  • Identification and function of a cytoplasmic K+ site of the Na+,K+-ATPase Schack VR, Morth JP, Toustrup-Jensen MS, Anthonisen AN, Nissen P, Andersen JP, Vilsen B
    JOURNAL OF BIOLOGICAL CHEMISTRY 283, 27982 (2008).
    DOI: 10.1074/jbc.M803506200
  • BIBF 1120: Triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy Hilberg F, Roth GJ, Krssak M, Kautschitsch S, Sommergruber W, Tontsch-Grunt U, Garin-Chesa P, Bader G, Zoephel A, Quant J, Heckel A, Rettig WJ
    CANCER RESEARCH 68, 4774 (2008).
    DOI: 10.1158/0008-5472.CAN-07-6307
  • A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions Grutter C, Wilkinson T, Turner R, Podichetty S, Finch D, McCourt M, Loning S, Jermutus L, Grutter MG
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 105, 20251 (2008).
    DOI: 10.1073/pnas.0807200106
  • Structural explanation for the role of Mn2+ in the activity of phi 6 RNA-dependent RNA polymerase Poranen MM, Salgado PS, Koivunen MRL, Wright S, Bamford DH, Stuart DI, Grimes JM
    NUCLEIC ACIDS RESEARCH 36, 6633 (2008).
    DOI: 10.1093/nar/gkn632
  • Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter Weyand S, Shimamura T, Yajima S, Suzuki S, Mirza O, Krusong K, Carpenter EP, Rutherford NG, Hadden JM, O'Reilly J, Ma P, Saidijam M, Patching SG, Hope RJ, Norbertczak HT, Roach PCJ, Iwata S, Henderson PJF, Cameron AD
    SCIENCE 322, 709 (2008).
    DOI: 10.1126/science.1164440
  • Structural analysis of B-box 2 from MuRF1: Identification of a novel self-association pattern in a RING-like fold Mrosek M, Meier S, Ucurum-Fotiadis Z, von Castelmur E, Hedbom E, Lustig A, Grzesiek S, Labeit D, Labeit S, Mayans O
    BIOCHEMISTRY 47, 10722 (2008).
    DOI: 10.1021/bi800733z
  • Trans-cis isomerization is responsible for the red-shifted fluorescence in variants of the red fluorescent protein eqFP611 Nienhaus K, Nar H, Heilker R, Wiedenmann J, Nienhaus GU
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 130, 12578 (2008).
    DOI: 10.1021/ja8046443
  • The C-terminal region of Ge-1 presents conserved structural features required for P-body localization Jinek M, Eulalio A, Lingel A, Helms S, Conti E, Izaurralde E
    RNA-A PUBLICATION OF THE RNA SOCIETY 14, 1991 (2008).
    DOI: 10.1261/rna.1222908
  • Residues in the HIV-1 Capsid Assembly Inhibitor Binding Site Are Essential for Maintaining the Assembly-competent Quaternary Structure of the Capsid Protein Bartonova V, Igonet S, Sticht J, Glass B, Habermann A, Vaney MC, Sehr P, Lewis J, Rey FA, Krausslich HG
    JOURNAL OF BIOLOGICAL CHEMISTRY 283, 32024 (2008).
    DOI: 10.1074/jbc.M804230200
  • Crystal structure of the termination module of a nonribosomal peptide synthetase Tanovic A, Samel SA, Essen LO, Marahiel MA
    SCIENCE 321, 659 (2008).
    DOI: 10.1126/science.1159850
  • Crystal structure of the cell wall anchor domain of MotB, a stator component of the bacterial flagellar motor: implications for peptidoglycan recognition ROUJEINIKOVA, A
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 15, 10348 (2008).
  • Atomic structure of the cross-beta spine of islet amyloid polypeptide (amylin) Wiltzius JJ, Sievers SA, Sawaya MR, Cascio D, Popov D, Riekel C, Eisenberg D
    PROTEIN SCIENCE 17, 1467 (2008).
  • Inhibition of the glucosyltransferase activity of clostridial Rho/Ras-glucosylating toxins by castanospermine Jank T, Ziegler MOP, Schulz GE, Aktories K
    FEBS LETTERS 582, 2277 (2008).
    DOI: 10.1016/j.febslet.2008.05.025
  • The FACT Spt16 "peptidase" domain is a histone H3-H4 binding module Stuwe T, Hothorn M, Lejeune E, Rybin V, Bortfeld M, Scheffzek K, Ladurner AG
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 105, 8884 (2008).
    DOI: 10.1073/pnas.0712293105
  • Thermodynamic characterization of allosteric glycogen phosphorylase inhibitors Anderka O, Loenze P, Klabunde T, Dreyer MK, Defossa E, Wendt KU, Schmoll D
    BIOCHEMISTRY 47, 4683 (2008).
    DOI: 10.1021/bi702397d
  • Modified uridines with c5-methylene substituents at the first position of the tRNA anticodon stabilize U center dot G wobble pairing during decoding Kurata S, Weixlbaumer A, Ohtsuki T, Shimazaki T, Wada T, Kirino Y, Takai K, Watanabe K, Ramakrishnan V, Suzuki T
    JOURNAL OF BIOLOGICAL CHEMISTRY 283, 18801 (2008).
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  • Matuzumab binding to EGFR prevents the conformational rearrangement required for dimerization Schmiedel J, Blaukat A, Li S, Knochel T, Ferguson KM
    CANCER CELL 13, 365 (2008).
  • Substrate binding, deprotonation, and selectivity at the periplasmic entrance of the Escherichia coli ammonia channel AmtB Javelle A, Lupo D, Ripoche P, Fulford T, Merrick M, Winkler FK
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 105, 5040 (2008).
  • Conformational Changes and Reaction of Clostridial Glycosylating Toxins Ziegler MOP, Jank T, Aktories K, Schulz GE
    JOURNAL OF MOLECULAR BIOLOGY 377, 1346 (2008).
  • Crystal structure of Ca2+ -free S100A2 at 1.6-A resolution Koch M, Diez J, Fritz G
    JOURNAL OF MOLECULAR BIOLOGY 378, 931 (2008).
  • Structural Basis for the Decarboxylation of Orotidine 5'-Monophosphate (OMP) by Plasmodium Falciparum OMP Decarboxylase Tokuoka K, Kusakari Y, Krungkrai SR, Matsumura H, Kai Y, Krungkrai J, Horii T, Inoue T
    JOURNAL OF BIOLOGICAL CHEMISTRY 143, 69 (2008).
  • Crystal structure of the yeast eIF4A-eIF4G complex: An RNA-helicase controlled by protein-protein interactions Schutz P, Bumann M, Oberholzer AE, Bieniossek C, Trachsel H, Altmann M, Baumann U
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 105, 9564 (2008).
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  • X-ray Structures of the Three Lactococcus lactis Dihydroxyacetone Kinase Subunits and of a Transient Intersubunit Complex Zurbriggen A, Jeckelmann JM, Christen S, Bieniossek C, Baumann U, Erni B
    JOURNAL OF BIOLOGICAL CHEMISTRY 283, 35789 (2008).
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  • Leaving Groups Prolong the Duration of 20S Proteasome Inhibition and Enhance the Potency of Salinosporamides Manam RR, McArthur KA, Chao TH, Weiss J, Ali JA, Palonibella VJ, Groll M, Lloyd GK, Palladino MA, Neuteboom STC, Macherla VR, Potts BCM
    JOURNAL OF MEDICINAL CHEMISTRY 51, 6711 (2008).
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  • Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction Schreiner P, Chen X, Husnjak K, Randles L, Zhang NX, Elsasser S, Finley D, Dikic I, Walters KJ, Groll M
    NATURE 453, 548 (2008).
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  • Proteasome inhibition by fellutamide B induces nerve growth factor synthesis Hines J, Groll M, Fahnestock M, Crews CM
    CHEMISTRY & BIOLOGY 15, 501 (2008).
    DOI: 10.1016/j.chembiol.2008.03.020
  • Structural Analysis of Spiro beta-Lactone Proteasome Inhibitors Groll M, Balskus EP, Jacobsen EN
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 130, 14981 (2008).
    DOI: 10.1021/ja806059t
  • Leaving groups prolong the duration of 20S proteasome inhibition and enhance the inhibition profile of salinosporamides Potts B, Manam R, Macherla V, Chao T, Weiss J, Groll M, McArthur K, Neuteboom S, Palladino M, Lloyd GK
    EJC SUPPLEMENTS 6, 74 (2008).
  • The multienzyme architecture of eukaryotic fatty acid synthases Leibundgut M, Maier T, Jenni S, Ban N
    CURRENT OPINION IN STRUCTURAL BIOLOGY 18, 714 (2008).
    DOI: 10.1016/j.sbi.2008.09.008
  • Structure of Reovirus sigma 1 in Complex with Its Receptor Junctional Adhesion Molecule-A Kirchner E, Guglielmi KM, Strauss HM, Dermody TS, Stehle T
    PLOS PATHOGENS 4, e1000235 (2008).
    DOI: 10.1371/journal.ppat.1000235
  • Structural basis of GM1 ganglioside recognition by simian virus 40 Neu U, Woellner K, Gauglitz G, Stehle T
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 105, 5219 (2008).
    DOI: 10.1073/pnas.0710301105
  • Structural basis for the regulated protease and chaperone function of DegP Krojer T, Sawa J, Schafer E, Saibil HR, Ehrmann M, Clausen T
    NATURE 453, 885 (2008).
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  • Structural biochemistry of a bacterial checkpoint protein reveals diadenylate cyclase activity regulated by DNA recombination intermediates Witte G, Hartung S, Buttner K, Hopfner KP
    MOLECULAR CELL 30, 167 (2008).
    DOI: 10.1016/j.molcel.2008.02.020
  • An Unusual RNA Recognition Motif Acts as a Scaffold for Multiple Proteins in the Pre-mRNA Retention and Splicing Complex Trowitzsch S, Weber G, Luhrmann R, Wahl MC
    JOURNAL OF BIOLOGICAL CHEMISTRY 283, 32317 (2008).
    DOI: 10.1074/jbc.M804977200
  • Structural and Functional Analysis of the E. coli NusB-S10 Transcription Antitermination Complex Luo X, Hsiao HH, Bubunenko M, Weber G, Court DL, Gottesman ME, Urlaub H, Wahl MC
    MOLECULAR CELL 32, 791 (2008).
    DOI: 10.1016/j.molcel.2008.10.028
  • Crystallization and preliminary X-ray analysis of the Thermoplasma acidophilum 20S proteasome in complex with protein substrates Felderer K, Groves M, Diez J, Pohl E, Witt S
    ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS 64, 899 (2008).
    DOI: 10.1107/S1744309108026791
  • X-Ray structure of HIV-1 protease in situ product complex Bihani S, Das A, Prashar V, Ferrer JL, Hosur MV
    PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 74, 594 (2008).
  • A putative alpha-helical porin from Corynebacterium glutamicum Ziegler K, Benz R, Schulz GE
    JOURNAL OF MOLECULAR BIOLOGY 379, 482 (2008).
    DOI: 10.1016/j.jmb.2008.04.017
  • Crystal structure of D351A and P312A mutant forms of the mammalian sarcoplasmic reticulum Ca2+-ATPase reveals key events in phosphorylation and Ca2+ release Marchand A, Winther AML, Holm PJ, Olesen C, Montigny C, Arnou B, Champeil P, Clausen JD, Vilsen B, Andersen JP, Nissen P, Jaxel C, Moller JV, Le Maire M
    JOURNAL OF BIOLOGICAL CHEMISTRY 283, 14867 (2008).
    DOI: 10.1074/jbc.M710165200
  • Structure of Reovirus σ1 in Complex with Its Receptor Junctional Adhesion Molecule-A Kirchner E, Guglielmi KM, Strauss HM, Dermody TS, Stehle T
    PLOS PATHOGENS 4, 1000235 (2008).
  • Generation and analysis of mesophilic variants of the thermostable archaeal I-DmoI homing endonuclease Prieto J, Epinat JC, Redondo P, Ramos E, Padro D, Cedrone F, Montoya G, Paques F, Blanco FJ
    JOURNAL OF BIOLOGICAL CHEMISTRY 283, 4364 (2008).
    DOI: 10.1074/jbc.M706323200
  • Molecular basis of histone H3K4me3 recognition by ING4 Palacios A, Munoz IG, Pantoja-Uceda D, Marcaida MJ, Torres D, Martin-Garcia JM, Luque I, Montoya G, Blanco FJ
    JOURNAL OF BIOLOGICAL CHEMISTRY 283, 15956 (2008).
    DOI: 10.1074/jbc.M710020200
  • Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases Redondo P, Prieto J, Munoz IG, Alibes A, Stricher F, Serrano L, Cabaniols JP, Daboussi F, Arnould S, Perez C, Duchateau P, Paques F, Blanco FJ, Montoya G
    NATURE 456, 107 (2008).
    DOI: 10.1038/nature07343
  • Crystal structure of I-Dmol in complex with its target DNA provides new insights into meganuclease engineering Marciada MJ, Prieto J, Redondo P, Nadra AD, Alibes A, Serrano L, Grizot S, Duchateau P, Paques F, Blanco FJ, Montoya G
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 105, 16888 (2008).
    DOI: 10.1073/pnas.0804795105
  • A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism Groll M, Schellenberg B, Bachmann AS, Archer CR, Huber R, Powell TK, Lindow S, Kaiser M, Dudler R
    NATURE 452, 755 (2008).
    DOI: 10.1038/nature06782
  • Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(Biol) ACP complex Cryle MJ, Schlichting I
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 105, 15696 (2008).
    DOI: 10.1073/pnas.0805983105
  • Activation of the life-span regulator p66(Shc) through reversible disulfide bond formation Gertz M, Fischer F, Wolters D, Steegborn C
    FEBS JOURNAL 275, 79 (2008).
  • A structural and biochemical basis for PAPS-independent sulfuryl transfer by aryl sulfotransferase from uropathogenic Escherichia coli Malojcic G, Owen RL, Grimshaw JP, Brozzo MS, Dreher-Teo H, Glockshuber R
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 105, 19217 (2008).
  • Infinite kinetic stability against dissociation of supramolecular protein complexes through donor strand complementation Puorger C, Eidam O, Capitani G, Erilov D, Grutter MG, Glockshuber R
    STRUCTURE 16, 631 (2008).
    DOI: 10.1016/j.str.2008.01.013
  • Helix swapping leads to dimerization of the N-terminal domain of the c-type cytochrome maturation protein CcmH from Escherichia coli Ahuja U, Rozhkova A, Glockshuber R, Thony-Meyer L, Einsle O
    FEBS LETTERS 582, 2779 (2008).
    DOI: 10.1016/j.febslet.2008.07.007
  • Preparation and structure of the charge-transfer intermediate of the transmembrane redox catalyst DsbB Malojcic G, Owen RL, Grimshaw JPA, Glockshuber R
    FEBS LETTERS 582, 3301 (2008).
    DOI: 10.1016/j.febslet.2008.07.063
  • Stabilizing ionic interactions in a full-consensus ankyrin repeat protein Merz T, Wetzel SK, Firbank S, Pluckthun A, Grutter MG, Mittl PRE
    JOURNAL OF MOLECULAR BIOLOGY 376, 232 (2008).
    DOI: 10.1016/j.jmb.2007.11.047
  • Structure of the recombinant antibody Fab fragment f3p4 Frey D, Huber T, Pluckthun A, Grutter MG
    ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 64, 636 (2008).
    DOI: 10.1107/S0907444908007282
  • Crystal structure of the ternary FimC-FimF(t)-FimD(N) complex indicates conserved pilus chaperone-subunit complex recognition by the usher FimD Eidam O, Dworkowski FSN, Glockshuber R, Grutter MG, Capitani G
    FEBS LETTERS 582, 651 (2008).
    DOI: 10.1016/j.febslet.2008.01.030
  • Structural basis of trans-inhibition in a molybdate/tungstate ABC transporter Gerber S, Comellas-Bigler M, Goetz BA, Locher KP
    SCIENCE 321, 246 (2008).
    DOI: 10.1126/science.1156213
  • Structural basis of enzyme encapsulation into a bacterial nanocompartment Sutter M, Boehringer D, Gutmann S, Guenther S, Prangishvili D, Loessner MJ, Stetter KO, Weber-Ban E, Ban N
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 15, 939 (2008).
    DOI: 10.1038/nsmb.1473
  • Atomic models of de novo designed cc beta-met amyloid-like fibrils Steinmetz MO, Gattin Z, Verel R, Ciani B, Stromer T, Green JM, Tittmann P, Schulze-Bdese C, Gross H, van Gunsteren WF, Meier BH, Serpell LC, Muller SA, Kammerer RA
    JOURNAL OF MOLECULAR BIOLOGY 376, 898 (2008).
    DOI: 10.1016/j.jmb.2007.11.100
  • Site-Directed Mutagenesis reveals Putative Substrate Binding Residues in the Escherichia coli RND Efflux Pump AcrB Bohnert JA, Schuster S, Seeger MA, Faehnrich E, Pos KM, Kern WV
    JOURNAL OF BACTERIOLOGY 190, 8225 (2008).
  • Crystal structure of the NADH-oxidizing FAD domain from the Na+-translocating NADH : quinone oxidoreductase (Na+-NQR) Tao M, Casutt M, Diez J, Fritz G, Steuber J
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 1777, S39 (2008).
    DOI: 10.1016/j.bbabio.2008.05.159
  • Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrB Seeger MA, von Ballmoos C, Eicher T, Brandstatter L, Verrey F, Diederichs K, Pos KM
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 15, 199 (2008).
    DOI: 10.1038/nsmb.1379
  • Arginine-induced conformational change in the c-ring/a-subunit interface of ATP synthase Vorburger T, Ebneter JZ, Wiedenmann A, Morger D, Weber G, Diederichs K, Dimroth P, von Ballmoos C
    FEBS JOURNAL 275, 2137 (2008).
    DOI: 10.1111/j.1742-4658.2008.06368.x
  • Expression, crystallization and preliminary X-ray analysis of an outer membrane protein from Thermus thermophilus HB27 Brosig A, Nesper J, Welte W, Diederichs K
    ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS 64, 533 (2008).
    DOI: 10.1107/S1744309108013602
  • Structure of the dissimilatory sulfite reductase from the hyperthermophilic archaeon Archaeoglobus fulgidus Schiffer A, Parey K, Warkentin E, Diederichs K, Huber H, Stetter KO, Kroneck PMH, Ermler U
    JOURNAL OF MOLECULAR BIOLOGY 379, 1063 (2008).
    DOI: 10.1016/j.jmb.2008.04.027
  • Omp85(Tt) from Thennus thermophilus HB27: an ancestral type of the omp85 protein family Nesper J, Brosig A, Ringler P, Patel GJ, Muller SA, Kleinschmidt JH, Boos W, Diederichs K, Welte W
    JOURNAL OF BACTERIOLOGY 190, 4568 (2008).
    DOI: 10.1128/JB.00369-08
  • The AcrB Efflux Pump: Conformational Cycling and Peristalsis Lead to Multidrug Resistance Seeger MA, Diederichs K, Eicher T, Brandstatter L, Schiefner A, Verrey F, Pos KM
    CURRENT DRUG TARGETS 9, 729 (2008).
  • Structural basis for chitotetraose coordination by CGL3, a novel galectin-related protein from Coprinopsis cinerea Walti MA, Walser PJ, Thore S, Grunler A, Bednar M, Kunzler M, Aebi M
    JOURNAL OF MOLECULAR BIOLOGY 379, 146 (2008).
    DOI: 10.1016/j.jmb.2008.03.062
  • An arginine switch in the species B adenovirus knob determines high-affinity engagement of the cellular receptor CD46 Persson BD, Mueller S, Reiter DM, Schmitt BBT, Marttila M, Sumowski CV, Schweizer S, Scheu U, Ochsenfeld C, Arnberg N, Stehle T
    JOURNAL OF VIROLOGY not known, not known (2008).
  • Structural basis of thiamine pyrophosphate analogues binding to the eukaryotic riboswitch Thore S, Frick C, Ban N
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 130, 8116 (2008).
  • Crystal Structure of the Major Allergen from Fire Ant Venom, Sol i 3 Padavattan S, Schmidt M, Hoffman DR, Markovic-Housley Z
    JOURNAL OF MOLECULAR BIOLOGY 383, 178 (2008).
    DOI: 10.1016/j.jmb.2008.08.023
  • Analysis of xenon binding to photosystem II by X-ray crystallography Murray JW, Maghlaoui K, Kargul J, Sugiura M, Barber J
    PHOTOSYNTHESIS RESEARCH 94, 1 (2008).
  • X-ray crystallography identifies two chloride binding sites in the oxygen evolving centre of Photosystem II Murray JW, Maghlaoui K, Kargul J, Ishida N, Lai TL, Rutherford AW, Sugiura M, Boussac A, Barber J
    ENERGY AND ENVIRONMENTAL SCIENCE 1, 161 (2008).
  • Structure of 2,6-dihydroxypyridine 3-hydroxylase from a nicotine-degrading pathway Treiber N, Schulz GE
    JOURNAL OF MOLECULAR BIOLOGY 379, 94 (2008).
  • Structure and mode of action of a mosquitocidal holotoxin Treiber N, Reinert DJ, Carpusca I, Aktories K, Schulz GE
    JOURNAL OF MOLECULAR BIOLOGY 381, 150 (2008).
  • The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning Wilson DN, Schluenzen F, Harms JM, Starosta AL, Connell SR, Fucini P
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 105, 13339 (2008).
    DOI: 10.1073/pnas.0804276105
  • A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation Connell SR, Topf M, Qin Y, Wilson DN, Mielke T, Fucini P, Nierhaus KH, Spahn CMT
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 15, 910 (2008).
    DOI: 10.1038/nsmb.1469
  • Ultralow-resolution ab initio phasing of filamentous proteins: crystals from a six-Ig fragment of titin as a case study Urzhumtsev A, von Castelmur E, Mayans O
    ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 64, 478 (2008).
    DOI: 10.1107/S0907444908003442
  • The crystal structure of a mammalian fatty acid synthase Maier T, Leibundgut M, Ban N
    SCIENCE 321, 1315 (2008).
    DOI: 10.1126/science.1161269
  • Structure-system correlation identifies a gene regulatory Mediator submodule Lariviere L, Seizl M, van Wageningen S, Rother S, van de Pasch L, Feldmann H, Strasser K, Hahn S, Holstege FCP, Cramer P
    GENES & DEVELOPMENT 22, 872 (2008).
    DOI: 10.1101/gad.465108
  • Crystallization of RNA polymerase I subcomplex A14/A43 by iterative prediction, probing and removal of flexible regions Geiger SR, Kuhn CD, Leidig C, Renkawitz J, Cramer P
    ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS 64, 413 (2008).
    DOI: 10.1107/S174430910800972X
  • Structure of eukaryotic RNA polymerases Cramer P, Armache KJ, Baumli S, Benkert S, Brueckner E, Buchen C, Damsma GE, Dengl S, Geiger SR, Jaslak AJ, Jawhari A, Jennebach S, Kamenski T, Kettenberger H, Kuhn CD, Lehmann E, Leike K, Sydow JE, Vannini A
    ANNUAL REVIEW OF BIOPHYSICS 37, 337 (2008).
    DOI: 10.1146/annurev.biophys.37.032807.130008
  • Structural basis of transcription inhibition by alpha-amanitin and implications for RNA polymerase II translocation Brueckner F, Cramer P
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 15, 811 (2008).
    DOI: 10.1038/nsmb.1458
  • DsbL and DsbI form a specific dithiol oxidase system for periplasmic arylsulfate sulfotransferase in uropathogenic Escherichia coli Grimshaw JPA, Stirnimann CU, Brozzo MS, Malojcic G, Gruetter MG, Capitani G, Glockshuber R
    JOURNAL OF MOLECULAR BIOLOGY 380, 667 (2008).
    DOI: 10.1016/j.jmb.2008.05.031
  • Crystal structure of Ca2+-free S100A2 at 1.6-angstrom resolution Koch M, Diez J, Fritz G
    JOURNAL OF MOLECULAR BIOLOGY 378, 933 (2008).
    DOI: 10.1016/j.jmb.2008.03.019
  • Vacuolar protein sorting: Two different functional states of the AAA-ATPase Vps4p Hartmann C, Chami M, Zachariae U, de Groot BL, Engel A, Grutter MG
    JOURNAL OF MOLECULAR BIOLOGY 377, 352 (2008).
    DOI: 10.1016/j.jmb.2008.01.010
  • Translational regulation via L11: Molecular switches on the ribosome turned on and off by thiostrepton and micrococcin Harms JM, Wilson DN, Schluenzen F, Connell SR, Stachelhaus T, Zaborowska Z, Spahn CMT, Fucini P
    MOLECULAR CELL 30, 26 (2008).
    DOI: 10.1016/j.molcel.2008.01.009
  • Auto-induction and purification of a Bacillus subtilis transglutaminase (Tgl) and its preliminary crystallographic characterization Placido D, Fernandes CG, Isidro A, Carrondo MA, Henriques AO, Archer M
    PROTEIN EXPRESSION AND PURIFICATION 59, 1 (2008).
    DOI: 10.1016/j.pep.2007.12.004
  • Conformational changes of a Swi2/Snf2 ATPase during its mechano-chemical cycle Lewis R, Durr H, Hopfner KP, Michaelis J
    NUCLEIC ACIDS RESEARCH 36, 1881 (2008).
    DOI: 10.1093/nar/gkn040
  • X-ray structure of the complete ABC enzyme ABCE1 from Pyrococcus abyssi Karcher A, Schele A, Hopfner KP
    JOURNAL OF BIOLOGICAL CHEMISTRY 283, 7962 (2008).
    DOI: 10.1074/jbc.M707347200
  • X-ray structure of a prokaryotic pentameric ligand-gated ion channel Hilf RJC, Dutzler R
    NATURE 452, 375 (2008).
    DOI: 10.1038/nature06717
  • A peptide deformylase-ribosome complex reveals mechanism of nascent chain processing Bingel-Erlenmeyer R, Kohler R, Kramer G, Sandikci A, Antolic S, Maier T, Schaffitzel C, Wiedmann B, Bukau B, Ban N
    NATURE 452, 108 (2008).
    DOI: 10.1038/nature06683
  • The C-terminal regulatory domain is the RNA 5 '-triphosphate sensor of RIG-I Cui S, Eisenacher K, Kirchhofer A, Brzozka K, Lammens A, Lammens K, Fujita T, Conzelmann KK, Krug A, Hopfner KP
    MOLECULAR CELL 29, 169 (2008).
    DOI: 10.1016/j.molcel.2007.10.032
  • Designed protein-protein association Grueninger D, Treiber N, Ziegler MO, Koetter JW, Schulze MS, Schulz GE
    SCIENCE 319, 206 (2008).
  • A regular pattern of Ig super-motifs defines segmental flexibility as the elastic mechanism of the titin chain. Von castelmur E, Marino M, Svergun DI, Kreplak L, Ucurum Z, Urthumzshev A, Konarev PV, Labeit D, Labeit S, Mayans O
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 105, 1186 (2008).
  • A rationally designed monomeric variant of anthranilate phosphoribosyltransferase from Sulfolobus solfataricus is as active as the dimeric wild-type enzyme but less thermostable Schwab T, Skegro D, Mayans O, Sterner R
    JOURNAL OF MOLECULAR BIOLOGY 376, 506 (2008).
  • Research Highlight: Platinum Result Wu B, Droege P, Davey C
    NATURE 451, 111 (2008).
  • Site Selectivity of Platinum Anticancer Therapeutics Wu B, Droege P, Davey C
    NATURE CHEMICAL BIOLOGY 4, 110 (2008).
  • Cloning, purification and preliminary X-ray analysis of the C-terminal domain of Helicobacter pylori MotB Roujeinikova A
    ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS n/a, n/a (2008).

2007

  • The structure of the cytoplasmic domain of the chloride channel CIC-Ka reveals a conserved interaction interface Markovic S, Dutzler R
    STRUCTURE 15, 715 (2007).
    DOI: 10.1016/j.str.2007.04.013
  • Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand Saremba S, Nickel J, Seher A, Kotzsch A, Sebald W, Mueller TD
    FEBS JOURNAL 275, 172 (2007).
  • Structure-Assisted Discovery of an Aminothiazole Derivative as a Lead Molecule for Inhibition of Bacterial Fatty-Acid Synthesis Pappenberger G, Schulz-Gasch T, Kusznir E, Mueller F, Hennig M
    ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 63, 1208 (2007).
  • The crystal structure of the ligand-binding module of human TAG-1 suggests a new mode of homophilic interaction Mortl M, Sonderegger P, Diederichs K, Welte W
    PROTEIN SCIENCE 16, 2174 (2007).
  • The 1.3-A resolution structure of Nitrosomonas europaea Rh50 and mechanistic implications for NH3 transport by Rhesus family proteins Lupo D, Li XD, Durand A, Tomizaki T, Cherif-Zahar B, Matassi G, Merrick M, Winkler FK
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 104, 19303 (2007).
  • An Hfq-like protein in archaea: Crystal structure and functional characterization of the Sm protein from Methanococcus jannaschii Nielsen JS, Boggild A, Andersen CB, Nielsen G, Boysen A, Brodersen DE, Valentin-Hansen P
    RNA-A PUBLICATION OF THE RNA SOCIETY 13, 2213 (2007).
  • 8-(3-(R)-Aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a Highly Potent, Selective, Long-Acting, and Orally Bioavailable DPP-4 Inhibitor for the Treatment of Type 2 Diabetes Eckhardt M, Langkopf E, Mark M, Tadayyon M, Thomas L, Nar H, Pfrengle W, Gut B, Lotz R, Sieger P, Fuchs H, Himmelsbach F
    JOURNAL OF MEDICINAL CHEMISTRY 50, 6450 (2007).
  • High Resolution Structure and Catalysis of O-Acetylserine Sulfhydrylase Isozyme B from Escherichia Coli Zocher G, Wiesand U, Schulz GE
    FEBS JOURNAL 274, 5382 (2007).
  • Critical Role of Desolvation in the Binding of 20-Hydroxyecdysone to the Ecdysone Receptor Browning C, Martin E, Loch C, Wurtz JM, Moras D, Stote RH, Dejaegere AP, Billas IML
    JOURNAL OF BIOLOGICAL CHEMISTRY 282, 32924 (2007).
  • The Structural Basis for Unidirectional Rotation of Thermoalkaliphilic F(1)-ATPase. Stocker A, Keis S, Vonck J, Cook GM, Dimroth P
    STRUCTURE 15, 904 (2007).
  • Engineering the substrate and inhibitor specificities of human coagulation Factor VIIa Larsen KS, Ostergaard H, Bjelke JR, Olsen OH, Rasmussen HB, Christensen L, Kragelund BB, Stennicke HR
    BIOCHEMICAL JOURNAL 405, 429 (2007).
  • Molecular and structural bases for the antigenicity of VP2 of infectious bursal disease virus Letzel T, Coulibaly F, Rey FA, Delmas B, Jagt E, van Loon AAMW, Mundt E
    JOURNAL OF VIROLOGY 81, 12827 (2007).
    DOI: 10.1128/JVI.01501-07
  • Structural Characterization of the Ribosome Maturation Protein, RimM Ssuzuki S, Tatsuguchi A, Matsumoto E, Kawazoe M, Kaminishi T, Shirouzu M, Muto Y, Takemoto C, Yokoyama S
    JOURNAL OF BACTERIOLOGY 189, 6397 (2007).
  • Crystallization and preliminary X-ray diffraction analysis on the homing endonuclease I-Dmo-I in complex with its target DNA Redondo P, Prieto J, Ramos E, Blanco FJ, Montoya G
    ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS 63, 1017 (2007).
    DOI: 10.1107/S1744309107049706
  • Functional architecture of RNA polymerase I Kuhn CD, Geiger SR, Baumli S, Gartmann M, Gerber J, Jennebach S, Mielke T, Tschochner H, Beckmann R, Cramer P
    CELL 131, 1260 (2007).
    DOI: 10.1016/j.cell.2007.10.051
  • Structural biology of RNA polymerase III: subcomplex C17/25 X-ray structure and 11 subunit enzyme model Jasiak AJ, Armache KJ, Martens B, Jansen RP, Cramer P
    FEBS JOURNAL 274, 92 (2007).
  • Structural aspects of RbfA action during small ribosomal subunit Datta PP, Wilson DN, Kawazoe M, Swami NK, Kaminishi T, Sharma MR, Booth TM, Takemoto C, Fucini P, Yokoyama S, Agrawal RK
    MOLECULAR CELL 28, 434 (2007).
    DOI: 10.1016/j.molcel.2007.08.026
  • Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors Connell SR, Takemoto C, Wilson DN, Wang HF, Murayama K, Terada T, Shirouzu M, Rost M, Schuler M, Giesebrecht J, Dabrowski M, Mielke T, Fucini P, Yokoyama S, Spahn CMT
    MOLECULAR CELL 25, 751 (2007).
    DOI: 10.1016/j.molcel.2007.01.027
  • AChBP-targeted alpha-conotoxin correlates distinct binding orientations with nAChR subtype selectivity Dutertre S, Ulens C, Buttner R, Fish A, van Elk R, Kendel Y, Hopping G, Alewood PF, Schroeder C, Nicke A, Smit AB, Sixma TK, Lewis RJ
    EMBO JOURNAL 26, 3858 (2007).
    DOI: 10.1038/sj.emboj.7601785
  • Inhibition of caspase-2 by a designed ankyrin repeat protein: Specificity, structure, and inhibition mechanism Schweizer A, Roschitzki-Voser H, Amstutz P, Briand C, Gulotti-Georgieva M, Prenosil E, Binz HK, Capitani G, Baici A, Pluckthun A, Grutter MG
    STRUCTURE 15, 625 (2007).
    DOI: 10.1016/j.str.2007.03.014
  • Drug export pathway of multidrug exporter AcrB revealed by DARPin inhibitors Sennhauser G, Amstutz P, Briand C, Storchenegger O, Grutter MG
    PLOS BIOLOGY 5, 106 (2007).
    DOI: 10.1371/journal.pbio.0050007
  • Stuctural basis for synthesis of inflammatory mediators by human leukotriene C4 synthase Martinez molina D, Wetterholm A, Kohl A, Mccarthy AA, Niegowski D, Ohlson E, Hammarberg T, Eshaghi S, Haeggstroem JZ, Nordlund P
    NATURE 448, 613 (2007).
  • Substrate spectrum of L-rhamnulose kinase related to models derived from two ternary complex structures Grueninger D, Schulz GE
    FEBS LETTERS 581, 3127 (2007).
  • Structure and action of the C-C bond-forming glycosyltransferase UrdGT2 involved in the biosynthesis of the antibiotic urdamycin Mittler M, Bechthold A, Schulz GE
    JOURNAL OF MOLECULAR BIOLOGY 372, 67 (2007).
  • Molecular Recognition and Interfacial Catalysis by the Essential Phosphatidylinositol Mannosyltransferase PimA from Mycobacteria Guerin ME, Kordulakova J, Schaeffer F, Svetlikova Z, Buschiazzo A, Giganti D, Gicquel B, Mikusova K, Jackson M, Alzari PM
    JOURNAL OF BIOLOGICAL CHEMISTRY 282, 20705 (2007).
  • Structural characterization of insulin NPH formulations Norrman M, Hubalek F, Schluckebier G
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 30, 414 (2007).
    DOI: 10.1016/j.ejps.2007.01.003
  • Structures of Human Monoamine Oxidase B Complexes with Selective Noncovalent Inhibitors: Safinamide and Coumarin Analogs Binda C, Wang J, Pisani L, Caccia C, Carotti A, Salvati P, Edmondson DE, Mattevi A
    JOURNAL OF MEDICINAL CHEMISTRY 50, 5848 (2007).
  • Structural Basis of LSD1-CoREST Selectivity in Histone H3 Recognition Forneris F, Binda C, Adamo A, Battaglioli E, Mattevi A
    JOURNAL OF BIOLOGICAL CHEMISTRY 282, 20070 (2007).
  • The crucial step in ether phospholipid biosynthesis: structural basis of a non-canonical reaction associated to a peroxisomal disorder Razeto A, Mattiroli F, Carpanelli E, Aliverti A, Pandini V, Coda A, Mattevi A
    STRUCTURE 15, 683 (2007).
  • Structure of a two-component monooxygenase Alfieri A, Ferini F, Ruangchan N, Prongjit M, Chaiyen P, Mattevi A
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 104, 1177 (2007).
  • Secondary and tertiary structure elasticity of titin Z1Z2 and a titin chain model Lee EH, Hsin J, Mayans O, Schulten K
    BIOPHYSICAL JOURNAL 93, 1719 (2007).
  • Generation and analysis of mesophilic variants of the thermostable I-DmoI homing endonuclease Prieto J, Epinat JC, Redondo P, Ramos E, Padro D, Montoya G, Paques F, Blanco F
    JOURNAL OF BIOLOGICAL CHEMISTRY Epub ahead of print, Epub ahead of print (2007).
  • Molecular architecture of the human GINS complex Boskovic J, Coloma J, Aparicio T, Zhou M, Robinson CV, Mendez J, Montoya G
    EMBO JOURNAL 8, 678 (2007).
  • The C-terminal loop of I-CreI is essential for DNA binding and cleavage. Identification of a novel site for specificity engineering in the I-CreI scaffold Prieto J, Redondo P, Padro D, Arnould S, Epinat J, Paques F, Blanco J, Montoya G
    NUCLEIC ACIDS RESEARCH 35, 3262 (2007).
  • Expression, purification, and crystallization of human CD5 domain III, a nanoscale crystallization example Rodamilans B, Ibanez S, Bragado-nilsson E, Sarrias R, Lozano M, Montoya G
    JOURNAL OF STRUCTURAL BIOLOGY 159, 144 (2007).
  • Proton uptake in the reaction center mutant L210DN from Rhodobacter sphaeroides via protonated water molecules Stachnik J, Hermes S, Onidas D, Hofmann E, Gerwert K
    PHOTOSYNTHESIS RESEARCH 91, 147 (2007).
  • Molecular determinants for the recruitment of the ubiquitin-ligase MuRF-1 onto M-line titin Mrosek M, Labeit D, Witt S, Heerklotz H, von Castelmur E, Labeit S, Mayans O
    FASEB JOURNAL 21, 1383 (2007).
    DOI: 10.1096/fj.06-7644com
  • Structural basis for reversible photoswitching in Dronpa Andresen M, Stiel AC, Trowitzsch S, Weber G, Eggeling C, Wahl MC, Hell SW, Jakobs S
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 104, 13005 (2007).
    DOI: 10.1073/pnas.0700629104
  • Early endosomal SNAREs form a structurally conserved SNARE complex and fuse liposomes with multiple topologies Zwilling D, Cypionka A, Pohl WH, Fasshauer D, Walla PJ, Wahl MC, Jahn R
    EMBO JOURNAL 26, 9 (2007).
    DOI: 10.1038/sj.emboj.7601467
  • Crystal structure of the plasma membrane proton pump Pedersen BP, Buch-Pedersen MJ, Morth JP, Palmgren MG, Nissen P
    NATURE 450, 1111 (2007).
    DOI: 10.1038/nature06417
  • Crystal structure of the sodium-potassium pump Morth JP, Pedersen BP, Toustrup-Jensen MS, Sorensen TLM, Petersen J, Andersen JP, Vilsen B, Nissen P
    NATURE 450, 1043 (2007).
    DOI: 10.1038/nature06419
  • The structural basis of calcium transport by the calcium pump Olesen C, Picard M, Winther AML, Gyrup C, Morth JP, Oxvig C, Moller JV, Nissen P
    NATURE 450, 1036 (2007).
    DOI: 10.1038/nature06418
  • Structural basis for a high affinity inhibitor bound to protein kinase MK2 Hillig RC, Eberspaecher U, Monteclaro F, Huber M, Nguyen D, Mengel A, Muller-Tiemann B, Egner U
    JOURNAL OF MOLECULAR BIOLOGY 369, 735 (2007).
    DOI: 10.1016/j.jmb.2007.03.004
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    ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS F63, 998 (2007).
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    PHOTOSYNTHESIS RESEARCH 91, 178 (2007).
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    RNA-A PUBLICATION OF THE RNA SOCIETY 13, 817 (2007).
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    NATURE STRUCTURAL & MOLECULAR BIOLOGY 14, 647 (2007).
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    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 50, 577 (2007).
  • Structure-function relationship of CAP-Gly domains Weisbrich A, Honnappa S, Jaussi R, Okhrimenko O, Frey D, Jelesarov I, Akhmanova A, Steinmetz MO
    NATURE STRUCTURAL & MOLECULAR BIOLOGY 14, 959 (2007).
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    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 104, 1213 (2007).
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  • Structure and quantum chemical characterization of chloroperoxidase compound 0, a common reaction intermediate of diverse heme enzymes Kuhnel K, Derat E, Terner J, Shaik S, Schlichting I
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 104, 99 (2007).
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  • Molecular and structural characterization of the PezAT chromosomal toxin-antitoxin system of the human pathogen Streptococcus pneumoniae Khoo SK, Loll B, Chan WT, Shoeman RL, Ngoo L, Yeo CC, Meinhart A
    JOURNAL OF BIOLOGICAL CHEMISTRY 282, 19606 (2007).
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  • Crystal structure of human estrogen-related receptor alpha in complex with a synthetic inverse agonist reveals its novel molecular mechanism Kallen J, Lattmann R, Beerli R, Blechschmidt A, Blommers MJJ, Geiser M, Ottl J, Schlaeppi JM, Strauss A, Fournier B
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  • Towards biological supramolecular chemistry: A variety of pocket-templated, individual metal oxide cluster nucleations in the cavity of a Mo/W-storage protein (vol 46, pg 2408, 2007) Schemberg J, Schneider K, Demmer U, Warkentin E, Muller A, Ermler U
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 46, 2970 (2007).
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  • A calcium-gated lid and a large beta-roll sandwich are revealed by the crystal structure of extracellular lipase from Serratia marcescens Meier R, Drepper T, Svensson V, Jaeger KE, Baumann U
    JOURNAL OF BIOLOGICAL CHEMISTRY 282, 31477 (2007).
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    NATURE STRUCTURAL & MOLECULAR BIOLOGY 14, 60 (2007).
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  • Structure of the prefusion form of the vesicular stomatitis virus glycoprotein G Roche S, Rey FA, Gaudin Y, Bressanelli S
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    JOURNAL OF SYNCHROTRON RADIATION 14, 11 (2007).
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    ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 63, 759 (2007).
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    BIOCHEMISTRY 46, 66 (2007).
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    JOURNAL OF MOLECULAR BIOLOGY 370(2), 331 (2007).
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    BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 1767, 404 (2007).
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    SCIENCE 317, 1387 (2007).
  • Structure of BeF(3)(-)-Modified Response Regulator PleD: Implications for Diguanylate Cyclase Activation, Catalysis, and Feedback Inhibition. Wassmann P, Chan C, Paul R, Beck A, Heerklotz H, Jenal U, Schirmer T
    STRUCTURE 15 (8), 915 (2007).
  • Uptake or extrusion: crystal structures of full ABC transporters suggest a common mechanism. Dawson RJ, Hollenstein K, Locher KP
    MOLECULAR MICROBIOLOGY 65, 250 (2007).
  • Structure of the multidrug ABC transporter Sav1866 from Staphylococcus aureus in complex with AMP-PNP. Dawson RJ, Locher KP
    FEBS LETTERS 581, 935 (2007).
  • Identification of a B-cell Epitope of Hyaluronidase, a Major Bee Venom Allergen, from its Crystal Structure in Complex with a Specific Fab Padavattan S, Schirmer T, Schmidt M, Aktis C, Valenta R, Mittermann I, Soldatova L, Slater J, Mueller U, Markovic Z
    JOURNAL OF MOLECULAR BIOLOGY 368, 742 (2007).
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    JOURNAL OF STRUCTURAL BIOLOGY 158, 455 (2007).
  • The reovirus sigma1 aspartic acid sandwich: a trimerization motif poised for conformational change. Schelling P, Guglielmi KM, Kirchner E, Paetzold B, Dermody TS, Stehle T
    JOURNAL OF BIOLOGICAL CHEMISTRY 282, 11582 (2007).
  • Human OLA1 defines an ATPase subfamily in the OBG family of GTP-binding proteins Koller-eichhorn R, Marquardt T, Gail R, Wittinghofer A, Kostrewa D, Kutay U, Kambach C
    JOURNAL OF BIOLOGICAL CHEMISTRY /doi/10.1074, /jbc.M700541200 (2007).
  • Crystal structure of the carboxyltransferase domain of the oxaloacetate decarboxylase Na+ pump from Vibrio cholerae Studer R, Dahinden P, Wang WW, Auchli Y, Li XD, Dimroth P
    JOURNAL OF MOLECULAR BIOLOGY 367, 547 (2007).
  • Expression, purification, crystallization and preliminary X-ray diffraction analysis of the DDX3 RNA helicase domain. Rodamilans B, Montoya G
    ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS 63, 283 (2007).
  • The C-terminal loop of the homing endonuclease I-CreI is essential for site recognition, DNA binding and cleavage Montoya G
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  • Crystal Structure of the Third Extracellular Domain of CD5 Reveals the Fold of a Group B Scavenger Cysteine-rich Receptor Domain Rodamilans B, Munoz I, Montoya G
    JOURNAL OF BIOLOGICAL CHEMISTRY 282, 12669 (2007).
  • Molecular and structural basis of polo-like kinase 1 substrate recognition: Implications in centrosomal localization. Garcia-Alvarez B, Carcer GD, Ibanez S, Bragado-nilsson E, Montoya G
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 104, 3107 (2007).
  • Adenovirus type 11 binding alters the conformation of its receptor CD46. Persson BD, Reiter DM, Marttila M, Mei YF, Casasnovas JM, Arnberg N, Stehle T
    NATURE STRUCTURAL AND MOLECULAR BIOLOGY 14(2), 164 (2007).
  • Cross-reactivity and 1.4-A crystal structure of Malassezia sympodialis thioredoxin (Mala s 13), a member of a new pan-allergen family Limacher A, Glaser AG, Meier C, Schmid-grendelmeier P, Zeller S, Scapozza L, Crameri R
    JOURNAL OF IMMUNOLOGY 178, 389 (2007).

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